1,975 results match your criteria Impetigo


Hydrochlorothizide-induced acute generalised exanthematous pustulosis presenting with bilateral periorbital impetigo.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Ascension Providence Hospital, Southfield, Michigan, USA.

Acute generalised exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction characterised by the appearance of erythematous plaques and papules with overlying non-follicular pinpoint pustules. Drugs are the cause of AGEP in approximately 90% of cases. The most common causes include anti-infective agents (aminopenicillins, quinolones, antibacterial sulfonamides and terbinafine), antimalarials and diltiazem. Read More

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http://dx.doi.org/10.1136/bcr-2017-223528DOI Listing
February 2019

Unraveling the Molecular Mechanism of Selective Antimicrobial Activity of 2(5)-Furanone Derivative against .

Int J Mol Sci 2019 Feb 6;20(3). Epub 2019 Feb 6.

Laboratory of Molecular Genetics of Microorganisms, Institute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlyovskaya street, Kazan 420008, Republic of Tatarstan, Russia.

causes various infectious diseases, from skin impetigo to life-threatening bacteremia and sepsis, thus appearing an important target for antimicrobial therapeutics. In turn, the rapid development of antibiotic resistance and biofilm formation makes it extremely robust against treatment. Here, we unravel the molecular mechanism of the antimicrobial activity of the recently unveiled consisting of three pharmacophores: chlorinated 2(5)-furanone, sulfone, and -menthol moieties. Read More

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http://dx.doi.org/10.3390/ijms20030694DOI Listing
February 2019

Reliability and accuracy of smartphones for paediatric infectious disease consultations for children with rash in the paediatric emergency department.

BMC Pediatr 2019 Jan 31;19(1):40. Epub 2019 Jan 31.

Department of Pediatric Emergency Department, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Objective: Smartphones and associated messaging applications have become the most common means of communication among health care workers and the general population. The aim of this study was to evaluate the reliability and accuracy of smartphones for the diagnosis of rash in children admitted to emergency departments during the night shift.

Methods: The images of the children who were admitted to the paediatric emergency department with rash were included in this study, and at least two images taken with smartphones by residents or paediatric infectious disease fellows were re-directed to the chief consultant of the Paediatric-Infectious Department via smartphone. Read More

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http://dx.doi.org/10.1186/s12887-019-1416-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354364PMC
January 2019
1 Read

Treatment resistant impetigo herpetiformis treated with infliximab.

Dermatol Ther 2019 Jan 28:e12839. Epub 2019 Jan 28.

Department of Pathology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.

Impetigo herpetiformis is a rare disease of pregnancy with the onset being in the second half of pregnancy and resolution after delivery. It is associated with a high rate of perinatal mortality and fetal abnormalities. Clinical and histological features of the disease are consistent with pustuler psoriasis. Read More

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http://doi.wiley.com/10.1111/dth.12839
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http://dx.doi.org/10.1111/dth.12839DOI Listing
January 2019
3 Reads

Ozenoxacin: a review of preclinical and clinical efficacy.

Expert Rev Anti Infect Ther 2019 Jan 28:1-10. Epub 2019 Jan 28.

a Red Española de Investigación en Patología Infecciosa (REIPI) , Madrid , Spain.

Introduction: Impetigo is the most common bacterial skin infection in children. Treatment is becoming complicated due to the development of antimicrobial resistance, especially in the main pathogen, Staphylococcus aureus. Ozenoxacin, a novel non-fluorinated topical quinolone antimicrobial, has demonstrated efficacy in impetigo. Read More

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http://dx.doi.org/10.1080/14787210.2019.1573671DOI Listing
January 2019

The effect of antimicrobial photodynamic therapy on the expression of biofilm associated genes in Staphylococcus aureus strains isolated from wound infections in burn patients.

Photodiagnosis Photodyn Ther 2019 Jan 23. Epub 2019 Jan 23.

Oral Microbiology Laboratory, Department of Microbiology, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Purpose: Burn patients are particularly susceptible to microbial infection. Staphylococcus aureus causes burn wound, impetigo and cellulitis. Although sub-lethal antimicrobial photodynamic therapy (aPDT) would not result in microorganism killing, it can considerably influence microbial virulence factor. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2019.01.028DOI Listing
January 2019
2 Reads

Erosio interdigitalis blastomycetica: A review of interdigital candidiasis.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Veterans Affairs Medical Center Brooklyn, New York SUNY Downstate, Department of Dermatology, Brooklyn, New York.

Erosio interdigitalis blastomycetica (EIB) is a Candida infection affecting the third web space, between the third and fourth fingers. In 1915, Gougerot and Goncea first described saccharomycetic organisms isolated from the hands and feet. Johannes Fabry later named it in 1917, well before the genus Candida was introduced in 1923. Read More

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August 2018
1 Read

Impetigo herpetiformis: a rare dermotosis of pregnancy.

Pan Afr Med J 2018 10;30:273. Epub 2018 Aug 10.

Dermatology Department, UHC Ibn Rochd, University of Medicine Hassan II, Casablanca, Morocco.

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http://dx.doi.org/10.11604/pamj.2018.30.273.16424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317388PMC

Exploration of a simplified clinical examination for scabies to support public health decision-making.

PLoS Negl Trop Dis 2018 12 27;12(12):e0006996. Epub 2018 Dec 27.

The Kirby Institute, University of New South Wales, Sydney, Australia.

Introduction: In most settings, the diagnosis of scabies is reliant on time-consuming and potentially intrusive clinical examination of all accesible regions of skin. With the recent recognition of scabies as a neglected tropical disease by the World Health Organization there is a need for standardised approaches to disease mapping to define populations likely to benefit from intervention, and to measure the impact of interventions. Development and validation of simplified approaches to diagnose scabies would facilitate these efforts. Read More

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http://dx.doi.org/10.1371/journal.pntd.0006996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307692PMC
December 2018
2 Reads

Treatment, prevention and public health management of impetigo, scabies, crusted scabies and fungal skin infections in endemic populations: a systematic review.

Trop Med Int Health 2018 Dec 24. Epub 2018 Dec 24.

Menzies School of Health Research, Charles Darwin University, Casuarina, Australia.

We conducted a systematic review of the treatment, prevention and public health control of skin infections including impetigo, scabies, crusted scabies and tinea in resource-limited settings where skin infections are endemic. The aim is to inform strategies, guidelines and research to improve skin health in populations that are inequitably affected by infections of the skin and the downstream consequences of these. The systematic review is reported according to the PRISMA statement. Read More

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http://doi.wiley.com/10.1111/tmi.13198
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http://dx.doi.org/10.1111/tmi.13198DOI Listing
December 2018
14 Reads

Sweet Syndrome in Pediatrics. A case report.

Rev Chil Pediatr 2018 Aug;89(4):511-515

Servicio de Anatomía Patológica, Hospital Roberto del Río, Chile.

Introduction: Sweet's syndrome is a very rare dermatosis in pediatrics, of unknown pathogenesis, clinically characterized by fever, neutrophilia, raised and painful plaques on the skin of the face, neck, and limbs, and histologically by dermal infiltration of neutrophils.

Objective: To present a clinical case of Sweet Syndrome in a pediatric patient.

Clinical Case: 3-years-old female child, with history of complex chromosomopathy 46XX add(8), with a 7-day history of plaques and blisters on the back and later also on the limbs, associated with high fever, without response to antibiotic treatment pres cribed due to suspicion of bullous impetigo. Read More

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http://dx.doi.org/10.4067/S0370-41062018005000603DOI Listing
August 2018
7 Reads

[Pemphigus vulgaris in pediatrics: A case report].

Rev Chil Pediatr 2018 Oct;89(5):650-654

Asociación Española, Montevideo, Uruguay.

Introduction: pemphigus vulgaris is a serious and infrequent disease in children. Its timely diagnosis and treatment allows modifying its prognosis. The objective is to describe its clinical characteristics, and the diagnostic and therapeutic approach of this uncommon autoimmune blistering disease in children. Read More

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http://dx.doi.org/10.4067/S0370-41062018005000708DOI Listing
October 2018
1 Read

Efficacy of Dalbavancin and Telavancin in the Treatment of Acute Bacterial Skin and Skin Structure Infections.

Maedica (Buchar) 2018 Sep;13(3):208-212

Assistant Professor, Department of Anatomy, Maheshwara Medical College and Hospital, Patancheru, Sangareddy District, Telangana, India.

Objectives: Two glycopeptide analogues, such as dalbavancin and telavancin, with improved pharmacokinetic/pharmacodynamic parameters have been developed. These two glycopeptide analogues are approved by Food and Drug Administration (FDA) for treatment of various Gram-positive bacterial skin infections.

Materials And Methods: We have conducted an open labelled prospective randomized study to compare the efficacy of these two drugs. Read More

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http://dx.doi.org/10.26574/maedica.2018.13.3.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290182PMC
September 2018

Diffuse facial rash in a former collegiate wrestler.

J Fam Pract 2018 Dec;67(12):783-785

San Antonio Uniformed Services Health Education Consortium, San Antonio, Texas, USA.

The patient described a history of "recurrent impetigo," which led to an uncommon diagnosis. Read More

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December 2018
5 Reads

Emergence of staphylococcal scalded skin syndrome associated with a new toxinogenic, methicillin-susceptible Staphylococcus aureus clone.

J Med Microbiol 2019 Jan 12;68(1):48-51. Epub 2018 Nov 12.

4​2nd Department of Paediatrics, School of Medicine, National and Kapodistrian University of Athens, Greece.

A sharp increase in staphylococcal scalded skin syndrome (SSSS) cases has been recorded in our settings since 2015, with 31 cases having been documented during the period 2014-2017. The molecular investigation of strains from the above period showed the emergence of a methicillin-susceptible, mupirocin- and fusidic acid-resistant Staphyloccocus aureus clone that belongs to the ST121 complex and carries both epidermolysin (eta/etb) genes. We concluded that the SSSS caused by the newly emerged, highly virulent community-associated-methicillin sensitive S. Read More

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http://dx.doi.org/10.1099/jmm.0.000871DOI Listing
January 2019
1 Read

Group A Streptococcus disease in Hong Kong children: an overview.

Hong Kong Med J 2018 Dec 9;24(6):593-601. Epub 2018 Nov 9.

Department of Paediatrics, Alberta Children's Hospital, The University of Calgary, Calgary, Alberta, Canada.

Group A β-haemolytic or is a gram-positive coccus that tends to grow in chains. is the cause of many important human diseases, ranging from pharyngitis and mild superficial skin infections to life-threatening systemic diseases. Infections typically begin in the throat or skin. Read More

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http://dx.doi.org/10.12809/hkmj187275DOI Listing
December 2018
4 Reads

Investigation of group A Streptococcus immune responses in an endemic setting, with a particular focus on J8.

Vaccine 2018 Nov 3;36(50):7618-7624. Epub 2018 Nov 3.

Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia; Centre for International Child Health, University of Melbourne, Australia; Department of Paediatrics, University of Melbourne, Royal Children's Hospital Melbourne, Parkville, Australia.

Sustained control of group A Streptococcus (GAS) infections in settings of poverty has proven to be challenging, and an effective vaccine may be the most practical long-term strategy to reduce GAS-related disease burden. Candidate GAS vaccines based on the J8 peptide have demonstrated promising immunogenicity in mice, however, less is known about the role of J8 antibodies in the human immune response to GAS infection. We analysed the stimulation of J8 antibodies in response to infection, and the role of existing J8 antibodies in protection against subsequent infection, using data collected in the Fijian population: (1) cross sectional population serosurvey; (2) paired serum collection for assessment of M-specific and J8 antibody responses; and (3) longitudinal assessment of GAS infection and immunity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X183148
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http://dx.doi.org/10.1016/j.vaccine.2018.10.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296486PMC
November 2018
8 Reads

Topical Antibacterial Agent for Treatment of Adult and Pediatric Patients With Impetigo: Pooled Analysis of Phase 3 Clinical Trials.

J Drugs Dermatol 2018 Oct;17(10):1051-1057

Ozenoxacin is a novel topical antibacterial agent with potent bactericidal activity against Gram-positive bacteria that has been developed as a 1% cream for treatment of impetigo. This article presents pooled results of pivotal clinical trials of ozenoxacin with the objective of evaluating the efficacy, safety, and tolerability of ozenoxacin 1% cream after twice-daily topical treatment for 5 days in patients with impetigo. A pooled analysis was performed of individual patient data from two multicenter, randomized, double-blind, vehicle-controlled phase 3 registration studies conducted in patients with impetigo. Read More

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October 2018
19 Reads

Impetigo incidence and treatment: a retrospective study of Dutch routine primary care data.

Fam Pract 2018 Oct 19. Epub 2018 Oct 19.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

Background: There is a lack of recently published data on impetigo presentation incidence and treatment practices in the routine Western European primary care setting.

Objectives: To investigate impetigo incidence, treatments and recurrence in primary care in the Netherlands.

Methods: A retrospective, observational study. Read More

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https://academic.oup.com/fampra/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/fampra/cmy104DOI Listing
October 2018
7 Reads

Skin and Soft Tissue Infections in the Emergency Department.

Emerg Med Clin North Am 2018 Nov;36(4):723-750

Department of Emergency Medicine, Highland Hospital, 1411 East 31st Street, Oakland, CA 94602, USA. Electronic address:

This article covers the diagnosis and treatment of skin and soft tissue infections commonly encountered in the emergency department: impetigo, cutaneous abscesses, purulent cellulitis, nonpurulent cellulitis, and necrotizing skin and soft tissue infections. Most purulent infections in the United States are caused by methicillin-resistant Staphylococcus aureus. For abscesses, we emphasize the importance of incision and drainage. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338627183005
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http://dx.doi.org/10.1016/j.emc.2018.06.005DOI Listing
November 2018
5 Reads

Comparative analysis of methicillin-resistant Staphylococcus aureus isolated from outpatients of dermatology unit in hospitals and clinics.

J Infect Chemother 2019 Mar 29;25(3):233-237. Epub 2018 Sep 29.

Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.

Community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) is a causative agent of intractable skin infections. In general, clinical symptoms of hospital outpatients with skin infections are severer than those of clinic patients. Hence, molecular epidemiological features of the CO-MRSA strains from hospital outpatients are predicted to be different from those of clinic patients. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.09.002DOI Listing
March 2019
3 Reads

Control Strategies for Scabies.

Trop Med Infect Dis 2018 Sep 5;3(3). Epub 2018 Sep 5.

Tropical Diseases, Murdoch Children's Research Institute, Parkville VIC 3052, Australia.

Scabies is a neglected tropical disease of the skin, causing severe itching and stigmatizing skin lesions. Further, scabies leads to impetigo, severe bacterial infections, and post-infectious complications. Around 200 million people are affected, particularly among disadvantaged populations living in crowded conditions in tropical areas. Read More

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http://www.mdpi.com/2414-6366/3/3/98
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http://dx.doi.org/10.3390/tropicalmed3030098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160909PMC
September 2018
15 Reads

A C126R Mutation in Leads to X-linked Chronic Granulomatous Disease With Recurrent Pneumonia and BCGitis.

Front Pediatr 2018 11;6:248. Epub 2018 Sep 11.

Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

Chronic granulomatous disease (CGD) is an innate immune deficiency of phagocytic cells caused by mutations that affect components of the NADPH oxidase system, with resulting impairment in reactive oxygen species production. Patients with CGD are susceptible to recurrent infections and hyperinflammatory responses. Mutations in lead to the X-linked form of CGD and are responsible for ~ 70% of cases. Read More

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https://www.frontiersin.org/article/10.3389/fped.2018.00248/
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http://dx.doi.org/10.3389/fped.2018.00248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141742PMC
September 2018
6 Reads

Infectious skin disorders encountered in a pediatric emergency department of a tertiary care hospital in Argentina: a descriptive study.

Int J Dermatol 2019 Mar 24;58(3):288-295. Epub 2018 Sep 24.

Head of the Pediatrics Department, Hospital Interzonal General de Agudos Presidente Perón, Sarandí, Avellaneda, Buenos Aires, Argentina.

Background: Infectious skin disorders (ISDs) are commonly seen in pediatric emergency departments (PED), however the exact frequency is unknown. We provide an accurate evaluation of the incidence and characteristics of ISDs diagnosed in a PED from Buenos Aires, Argentina, over a 1-year period.

Methods: Prospectively, descriptive study of children evaluated in the PED with ISDs during 2016. Read More

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http://dx.doi.org/10.1111/ijd.14234DOI Listing
March 2019
6 Reads

Anetodermic lesions following pityriasis rosea and impetigo.

G Ital Dermatol Venereol 2018 Sep 18. Epub 2018 Sep 18.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, I.R.C.C.S. Foundation, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.23736/S0392-0488.18.06115-1DOI Listing
September 2018
2 Reads

Skin diseases associated with atopic dermatitis.

Clin Dermatol 2018 Sep - Oct;36(5):631-640. Epub 2018 Jun 1.

Department of Dermatology, Mt Sinai West, Icahn School of Medicine at Mt Sinai, New York, NY. Electronic address:

Atopic dermatitis is a common chronic pruritic inflammatory skin disorder, characterized by an abnormal skin barrier, immune dysfunction, and an altered skin microbiome. Atopic dermatitis may be seen in conjunction with a variety of other skin disorders due to the complex pathogenesis of atopic dermatitis, involving genetic and environmental factors that are associated with immune dysfunction, barrier defects, and altered skin microbiomes. Skin disorders associated with atopic dermatitis include diseases sharing similar genetic origins like ichthyosis vulgaris, infectious diseases such as impetigo, and eczema herpeticum, in addition to the cutaneous autoimmune diseases, alopecia areata, and vitiligo. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2018.05.004DOI Listing
January 2019
8 Reads

Atypical case of mucous membrane pemphigoid in a 26-year-old man.

BMJ Case Rep 2018 Sep 12;2018. Epub 2018 Sep 12.

Department of Ophthalmology, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.

A 26-year-old Caucasian man with no previous history of chemical injury presenting with an inability to open his right eye was investigated for mucous membrane pemphigoid and treated. Examination was notable for symblepharon of the right eye and impetigo-like lesions on the face and neck. A biopsy with immunohistochemical analysis was significant for linear deposits of C3 and immunoglobulin G at the level of the epithelial basement membrane, confirming the diagnosis of mucous membrane pemphigoid. Read More

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http://dx.doi.org/10.1136/bcr-2018-225872DOI Listing
September 2018
3 Reads

Is impetigo a missed opportunity for scabies treatment?

N Z Med J 2018 Aug 31;131(1481):78-81. Epub 2018 Aug 31.

Medical Officer, Auckland Regional Public Health Service, Greenlane Clinical Centre, Greenlane West, Auckland.

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August 2018
14 Reads

[Investigation of Streptococcus pyogenes virulence factors and typing by multiple locus variable number tandem repeat fingerprinting (MLVF) method].

Mikrobiyol Bul 2018 Jul;52(3):233-246

Selçuk University Faculty of Medicine, Department of Medical Microbiology, Konya, Turkey.

Streptococcus pyogenes is an important bacterial pathogen that colonizes the throat and skin of human beings and causes a wide variety of diseases ranging from mild infections like pharyngitis, tonsillitis and impetigo to severe invasive infections such streptococcal toxic shock syndrome, septicemia, and necrotizing fasciitis, and produces a wide variety of virulence factors. The aim of this study was to investigate the antibiotic resistance, virulence genes; [pyrogenic exotoxin genes (speA, C, G, H, I, J, K, L, M, smeZ and ssa), deoxyribonuclease genes (sdaB, spd3, sdc ve sdaD), protease genes (speB, spyCEP ve scpA) and inhibitor genes (mac and sic)] of S.pyogenes strains isolated from throat cultures of patients with symptomatic tonsillo-pharyngitis and typing by multiple locus variable number tandem repeat fingerprinting (MLVF) method. Read More

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http://www.mikrobiyolbul.org/linkout.aspx?pmid=30156510
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http://dx.doi.org/10.5578/mb.66841DOI Listing
July 2018
17 Reads

Skin Infections.

Prim Care 2018 Sep;45(3):433-454

Department of Family Medicine, Tidelands Health MUSC Family Medicine Residency Program, 4320 Holmestown Road, Myrtle Beach, SC 29588, USA.

The primary care provider will commonly see skin and soft tissue infections in the outpatient setting. Skin and soft tissue infections range from the uncomplicated impetigo to the potentially lethal necrotizing fasciitis. This article reviews these infections based on their underlying etiology: bacterial, fungal, and viral causes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00954543183004
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http://dx.doi.org/10.1016/j.pop.2018.05.004DOI Listing
September 2018
29 Reads

Secondary syphilis presented with impetigo-like lesions: a rare case report.

Int J Dermatol 2018 11 10;57(11):e141-e142. Epub 2018 Aug 10.

Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1111/ijd.14134DOI Listing
November 2018
10 Reads

Structure of ScpC, a virulence protease from , reveals the functional domains and maturation mechanism.

Biochem J 2018 Sep 11;475(17):2847-2860. Epub 2018 Sep 11.

Department of Biological Sciences, 14 Science Drive 4, National University of Singapore, Singapore 117543

Group A Streptococcus (GAS; ) causes a wide range of infections, including pharyngitis, impetigo, and necrotizing fasciitis, and results in over half a million deaths annually. GAS ScpC (SpyCEP), a 180-kDa surface-exposed, subtilisin-like serine protease, acts as an essential virulence factor that helps evade the innate immune response by cleaving and inactivating C-X-C chemokines. ScpC is thus a key candidate for the development of a vaccine against GAS and other pathogenic streptococcal species. Read More

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http://biochemj.org/lookup/doi/10.1042/BCJ20180145
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http://dx.doi.org/10.1042/BCJ20180145DOI Listing
September 2018
15 Reads
4.400 Impact Factor

Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study.

PLoS Negl Trop Dis 2018 07 25;12(7):e0006668. Epub 2018 Jul 25.

Victorian Infectious Disease Reference Laboratory, The Royal Melbourne Hospital and The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.

Background: Skin sores caused by Group A streptococcus (GAS) infection are a major public health problem in remote Aboriginal communities. Skin sores are often associated with scabies, which is evident in scabies intervention programs where a significant reduction of skin sores is seen after focusing solely on scabies control. Our study quantifies the strength of association between skin sores and scabies among Aboriginal children from the East Arnhem region in the Northern Territory. Read More

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http://dx.doi.org/10.1371/journal.pntd.0006668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078322PMC
July 2018
4 Reads

An effective and promising treatment with adalimumab for impetigo herpetiformis with postpartum flare-up.

Int J Dermatol 2019 Mar 20;58(3):350-353. Epub 2018 Jul 20.

Department of Dermatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.

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http://dx.doi.org/10.1111/ijd.14141DOI Listing
March 2019
3 Reads

Randomised trial of community treatment with azithromycin and ivermectin mass drug administration for control of scabies and impetigo.

Clin Infect Dis 2018 Jul 7. Epub 2018 Jul 7.

Group A Streptococcal Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

Background: Scabies is a public health problem in many countries, with impetigo and its complications important consequences. Ivermectin based mass drug administration (MDA) reduces the prevalence of scabies and, to a lesser extent, impetigo. We studied the impact of co-administering azithromycin on the prevalence of impetigo and antimicrobial resistance. Read More

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http://dx.doi.org/10.1093/cid/ciy574DOI Listing
July 2018
10 Reads
1 Citation
8.890 Impact Factor

Ozenoxacin: A Novel Topical Quinolone for Impetigo.

Ann Pharmacother 2018 Dec 2;52(12):1233-1237. Epub 2018 Jul 2.

1 Auburn University Harrison School of Pharmacy, Auburn, AL, USA.

Objective: To review the data supporting Food and Drug Administration (FDA) labeling of ozenoxacin and evaluate its place in therapy for impetigo.

Data Sources: A literature search was conducted using PubMed (1966 to May 2018) and Google Scholar (2000 to May 2018) with the search terms ozenoxacin, T-3912, and GF-001001-00. Other resources included clinicaltrials. Read More

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http://dx.doi.org/10.1177/1060028018786510DOI Listing
December 2018
6 Reads

Scabies Itch.

Dermatol Clin 2018 Jul 1;36(3):301-308. Epub 2018 May 1.

Dermatology Department, AP-HP, Hôpital Henri Mondor, 51 avenue du Maréchal de Lattre de Tassigny, 94010 Créteil, France; EpiDermE, Epidé miologie en Dermatologie et Evaluation des Thé rapeutiques, Université Paris-Est Créteil, EA 7379, 9400 Créteil, France.

Itch is the cardinal symptom of scabies, present in more than 90% of the cases, generalized and intense, worsening at night, and often sparing the head. The primary complications of the itch in scabies are secondary bacterial infections and psychosocial issues leading to impairment on life quality. Currently, there are no specific data analyzing mechanisms of the itch in scabies, but the latest progress made in the understanding of host-mite interactions may help to improve understanding. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338635183002
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http://dx.doi.org/10.1016/j.det.2018.02.009DOI Listing
July 2018
7 Reads

Efficacy and Safety of Ozenoxacin Cream for Treatment of Adult and Pediatric Patients With Impetigo: A Randomized Clinical Trial.

JAMA Dermatol 2018 Jul;154(7):806-813

John P. and Katherine G. McGovern Medical School, Houston, Texas.

Importance: Ozenoxacin, a novel topical antibacterial agent with potent bactericidal activity against gram-positive bacteria, has been developed as a cream with 1% active drug for the treatment of impetigo, a highly contagious bacterial skin infection.

Objectives: To evaluate the efficacy, safety, and tolerability of ozenoxacin cream, 1%, after 5-day twice-daily topical treatment in patients with impetigo.

Design, Setting, And Participants: This randomized, double-blind, vehicle-controlled clinical trial included patients 2 months or older with impetigo who were enrolled at centers in 6 countries from June 2, 2014, through May 30, 2015. Read More

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http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamadermatol.2018.1103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128489PMC
July 2018
54 Reads

Clinical and microbiological properties of Staphylococcus lugdunensis skin infections.

J Dermatol 2018 Aug 13;45(8):994-999. Epub 2018 Jun 13.

Department of Dermatology, Rambam Health Care Campus, Technion, Haifa, Israel.

Staphylococcus lugdunensis is an emerging pathogen in skin and soft tissue infections that was previously considered a commensal. The aim of this study was to elucidate the characteristics of skin infections by S. lugdunensis and its appropriate management, in a tertiary referral medical center. Read More

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http://dx.doi.org/10.1111/1346-8138.14496DOI Listing
August 2018
25 Reads

Interleukin (IL)-8 and IL-36γ but not IL-36Ra are related to acrosyringia in pustule formation associated with palmoplantar pustulosis.

Clin Exp Dermatol 2019 Jan 12;44(1):52-57. Epub 2018 Jun 12.

Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.

Background: Palmoplantar pustulosis (PPP) is a refractory, nonbacterial impetigo confined to the palms and soles. Its pathogenesis is still obscure, but it may be associated with the large eccrine sweat glands and pores of palmoplantar skin. PPP is considered to be a localized pustular psoriasis. Read More

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http://dx.doi.org/10.1111/ced.13689DOI Listing
January 2019
4 Reads

Scabies and impetigo in Timor-Leste: A school screening study in two districts.

PLoS Negl Trop Dis 2018 05 31;12(5):e0006400. Epub 2018 May 31.

Paediatric Department, Royal Darwin Hospital, Darwin, Australia.

Introduction: Scabies and impetigo are common and important skin conditions which are often neglected in developing countries. Limited data have been published on the prevalence of scabies and impetigo in Timor-Leste. Sequelae including cellulitis, bacteraemia, nephritis, acute rheumatic fever and rheumatic heart disease contribute significantly to the burden of disease. Read More

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http://dx.doi.org/10.1371/journal.pntd.0006400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997349PMC
May 2018
5 Reads

Impetigo Herpetiformis: Review of Pathogenesis, Complication, and Treatment.

Dermatol Res Pract 2018 4;2018:5801280. Epub 2018 Apr 4.

Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Impetigo herpetiformis (IH) is among rare dermatosis of pregnancy, which is currently considered as a form of generalized pustular psoriasis. It is diagnosed by characteristic lesions of erythematous patches and grouped pustules mostly in the third trimester of pregnancy and may have systemic associations. A variety of complications have been reported in the course of IH. Read More

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http://dx.doi.org/10.1155/2018/5801280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904797PMC
April 2018
5 Reads

Current State of Nanomedicines in the Treatment of Topical Infectious Disorders.

Recent Pat Antiinfect Drug Discov 2018 ;13(2):127-150

University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Studies, Panjab University, Chandigarh 160 014, India.

Background: Topical infections, involving a number of diseases such as impetigo, eczema, pustular acne, psoriasis and infected seborrheic dermatitis are one among the many challenges to health which stand out for their profound impact on human species. The treatment of topical infections has always been a difficult proposition because of the lack of efficacy of existing anti-infectives, longer period of treatment and yet incomplete recovery. The increasing emergence of antibiotic resistant bacterial strains like Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa undermines the need for the development of new delivery systems to enhance the therapeutic efficacy of existing topical anti-infectives. Read More

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http://dx.doi.org/10.2174/1574891X13666180529103804DOI Listing
January 2019
4 Reads

Bilateral Periorbital Impetigo Inducing Significant Dermatitis and Cicatricial Eyelid Changes in an Adult.

Ophthalmology 2018 Jun;125(6):798

Massachusetts Eye and Ear Infirmary, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ophtha.2018.02.021DOI Listing

Atopic dermatitis complicated by severe impetigo in a Syrian refugee infant.

BMJ Case Rep 2018 May 14;2018. Epub 2018 May 14.

Department of Medicine, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

We present the case of a 3-month-old infant with atopic dermatitis who developed severe impetigo. The child was born to Syrian refugees shortly after they arrived in Canada. The case demonstrates the rapid and nearly complete resolution of dramatic skin findings after a course of hydrocortisone ointment and oral antibiotics with adjuvant measures. Read More

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http://dx.doi.org/10.1136/bcr-2017-223149DOI Listing
May 2018
3 Reads

A case of pustular psoriasis of pregnancy with positive maternal-fetal outcomes.

Cutis 2018 Apr;101(4):278-280

Department of Dermatology, University of Rochester, New York, USA.

Pustular psoriasis of pregnancy (PPP), also known as impetigo herpetiformis, is a rare condition that affects women in the third trimester of pregnancy through the postpartum period. The relative infrequency of PPP presents both clinical and pathologic challenges in the diagnosis and management of this condition. We report a case of a woman who presented at 32 weeks' gestation with a generalized rash demonstrating clinicopathologic features consistent with PPP. Read More

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April 2018
3 Reads

Comparative in vitro antibacterial activity of ozenoxacin against Gram-positive clinical isolates.

Future Microbiol 2018 05;13:3-19

Medical Department, Ferrer Internacional, Barcelona, Spain.

Aim: To compare the in vitro activity of the anti-impetigo agent, ozenoxacin, and other antimicrobial agents against Gram-positive clinical isolates from skin and soft tissue infections.

Materials & Methods: Isolates were collected in two studies: 1097 isolates from 49 centers during 2009-2010 and 1031 isolates from ten centers during 2014. Minimum inhibitory concentrations were determined for 18 and 11 antimicrobials in these studies, respectively, using standard broth microdilution methods. Read More

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https://www.futuremedicine.com/doi/10.2217/fmb-2017-0289
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http://dx.doi.org/10.2217/fmb-2017-0289DOI Listing
May 2018
11 Reads

A review of the antibacterial activity of ozenoxacin.

Future Microbiol 2018 05;13:1-2

Spherium Biomed, Barcelona, Spain.

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https://www.futuremedicine.com/doi/10.2217/fmb-2018-0069
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http://dx.doi.org/10.2217/fmb-2018-0069DOI Listing
May 2018
5 Reads

Therapeutic efficacy of ozenoxacin in animal models of dermal infection with Staphylococcus aureus.

Future Microbiol 2018 05;13:21-30

Medical Department, Ferrer Internacional, Barcelona, Spain.

Aim: To assess different concentrations and formulations of topical ozenoxacin using a mouse model of Staphylococcus aureus dermal infection for identification of the best formulation for treating patients with impetigo.

Materials & Methods: The efficacy of ozenoxacin formulations was compared with vehicle control, mupirocin and retapamulin ointments in a mouse model.

Results: The most effective concentrations of ozenoxacin for reducing S. Read More

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http://dx.doi.org/10.2217/fmb-2017-0290DOI Listing
May 2018
6 Reads