542 results match your criteria Impairment Rating and Disability Determination


Poor self-perceived health is associated with frailty and prefrailty in urban living older adults: A cross-sectional analysis.

Geriatr Nurs 2020 Jun 3. Epub 2020 Jun 3.

Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Geriatrics, No. 45 Changchun Street, Beijing 100053, China; National Clinical Research Center for Geriatric Disorders, Beijing, China; Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Key Laboratory for Parkinson's Disease, Parkinson Disease Center of Beijing Institute for Brain Disorders, Beijing, China; Clinical Center for Parkinson's Disease, Capital Medical University, Beijing, China; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China. Electronic address:

In this study, we investigated the cross-sectional association of Self-perceived health (SPH) with frailty phenotype. A total of 4632 participants of the Beijing Longitudinal Study of Aging II (mean age 75.4 ± 6. Read More

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http://dx.doi.org/10.1016/j.gerinurse.2020.05.003DOI Listing

Psychometric assessment and validation of the dysphagia severity rating scale in stroke patients.

Sci Rep 2020 Apr 29;10(1):7268. Epub 2020 Apr 29.

GI Sciences, Division of Diabetes, Endocrinology and Gastroenterology, School of Medicine Sciences, University of Manchester and the Manchester Academic Health Sciences Centre, Manchester, UK.

Post stroke dysphagia (PSD) is common and associated with poor outcome. The Dysphagia Severity Rating Scale (DSRS), which grades how severe dysphagia is based on fluid and diet modification and supervision requirements for feeding, is used for clinical research but has limited published validation information. Multiple approaches were taken to validate the DSRS, including concurrent- and predictive criterion validity, internal consistency, inter- and intra-rater reliability and sensitivity to change. Read More

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http://dx.doi.org/10.1038/s41598-020-64208-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190822PMC

Cross-cultural translation, adaptation and validation of a Japanese version of the functional index for hand osteoarthritis (J-FIHOA).

BMC Musculoskelet Disord 2020 Mar 16;21(1):173. Epub 2020 Mar 16.

Department of Hand Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Background: Hand osteoarthritis (OA) has a wide spectrum of clinical presentations and physical function is one of the core domains where patients suffer. The Functional Index for Hand Osteoarthritis (FIHOA) is a leading assessment tool for hand OA-related functional impairment. Our objective was to make a Japanese version of FIHOA (J-FIHOA) and validate it among Japanese hand OA patients. Read More

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http://dx.doi.org/10.1186/s12891-020-03193-6DOI Listing

Depression and Functional Outcomes in Patients Presenting to the Emergency Department With Low Back Pain.

Acad Emerg Med 2020 Mar 9. Epub 2020 Mar 9.

From the, Division of Emergency Medicine, Department of Surgery, Duke University, Durham, NC.

Objectives: Low back pain (LBP) is a common reason for patients to present to emergency departments (EDs). Our objective was to describe the associations between depressive symptoms, pain severity, and functional impairment up to 3 months after initial ED presentation for LBP.

Methods: We performed a secondary analysis on an observational cohort of adult patients from a high-volume, urban ED. Read More

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http://dx.doi.org/10.1111/acem.13957DOI Listing

Long-term effects of bilateral pallidal deep brain stimulation in dystonia: a follow-up between 8 and 16 years.

J Neurol 2020 Jun 13;267(6):1622-1631. Epub 2020 Feb 13.

Movement Disorder and Neuromodulation Unit, Department of Neurology, Charité, University Medicine Berlin, Campus Mitte, Charitéplatz 1, 10117, Berlin, Germany.

Objective: Observational study to evaluate the long-term motor and non-motor effects of deep brain stimulation (DBS) of the globus pallidus internus (GPi) on medically refractory dystonia.

Background: Dystonia is a chronic disease affecting mainly young patients with a regular life expectancy and lifelong need for therapy. Pallidal DBS is an established treatment for severe isolated dystonia but long-term data are sparse. Read More

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http://dx.doi.org/10.1007/s00415-020-09745-zDOI Listing

Gender differences in the surgical management of lumbar degenerative disease: a scoping review.

J Neurosurg Spine 2020 Jan 31:1-18. Epub 2020 Jan 31.

1Division of Neurosurgery, Dalhousie University QEII Health Sciences Centre, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada; and.

Objective: Despite efforts toward achieving gender equality in clinical trial enrollment, females are often underrepresented, and gender-specific data analysis is often unavailable. Identifying and reducing gender bias in medical decision-making and outcome reporting may facilitate equitable healthcare delivery. Gender disparity in the utilization of surgical therapy has been exemplified in the orthopedic literature through studies of total joint arthroplasty. Read More

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http://dx.doi.org/10.3171/2019.11.SPINE19896DOI Listing
January 2020

Effects of desvenlafaxine versus placebo on MDD symptom clusters: A pooled analysis.

J Psychopharmacol 2020 Mar 8;34(3):280-292. Epub 2020 Jan 8.

Pfizer Canada, Inc., Kirkland, QC, Canada.

Background: Major depressive disorder is characterized by the presence of at least five of nine specific symptoms that contribute to clinically significant functional impairment. This analysis examined the effect of desvenlafaxine (50 or 100 mg) versus placebo on symptom cluster scores and the association between early improvement in symptom clusters and symptomatic or functional remission at week 8.

Methods: Using data from nine double-blind, placebo-controlled studies of desvenlafaxine for the treatment of major depressive disorder (=4317), the effect of desvenlafaxine 50 or 100 mg versus placebo on scores for symptom clusters based on 17-item Hamilton Rating Scale for Depression items was assessed using analysis of covariance. Read More

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http://dx.doi.org/10.1177/0269881119896066DOI Listing

Depression Severity, but Not Cognitive Impairment or Frailty, is Associated with Disability in Late-Life Depression.

Clin Gerontol 2020 Jul-Sep;43(4):411-419. Epub 2019 Dec 21.

Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center , San Francisco, California, USA.

Objectives: Assess the relationship of cognitive impairment to disability, accounting for depression severity and frailty, among older adults with late-life depression (LLD).

Methods: Data were analyzed from 78 community-dwelling older adults with LLD and without dementia (age = 71.9; = 6. Read More

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http://dx.doi.org/10.1080/07317115.2019.1699882DOI Listing
December 2019

Cell-based therapies for amyotrophic lateral sclerosis/motor neuron disease.

Cochrane Database Syst Rev 2019 12 19;12:CD011742. Epub 2019 Dec 19.

Taylor's University, School of Medicine, Subang Jaya, Malaysia.

Background: Amyotrophic lateral sclerosis (ALS), which is also known as motor neuron disease (MND), is a fatal disease associated with rapidly progressive disability, for which no definitive treatment exists. Current treatment approaches largely focus on relieving symptoms to improve the quality of life of those affected. The therapeutic potential of cell-based therapies in ALS/MND has not been fully evaluated, given the paucity of high-quality clinical trials. Read More

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http://dx.doi.org/10.1002/14651858.CD011742.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920743PMC
December 2019

Comparative Analysis of Visual System Disability Evaluation Criteria between China and the United States.

Authors:
R J Liu W T Xia

Fa Yi Xue Za Zhi 2019 Oct 25;35(5):607-612. Epub 2019 Oct 25.

Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China.

Abstract: Gradation of Disability in Human Body Injuries (hereinafter referred to as Gradation) has been released and used since January 2017, and has become the most widely used standard in forensic science practice. This paper calculates and rates the visual system evaluation provisions of the current domestic disability evaluation criteria represented by the Gradation which used the methods of Guides to the Evaluation of Permanent Impairment (hereinafter referred to as GEPI) issued by American Medical Association (AMA). Through comparing, a good correlation between the provisions in Gradation and whole person impairment rating index in GEPI was shown. Read More

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http://dx.doi.org/10.12116/j.issn.1004-5619.2019.05.018DOI Listing
October 2019

Assessor- and participant-blinded, randomized controlled trial of dense cranial electroacupuncture stimulation plus body acupuncture for neuropsychiatric sequelae of stroke.

Psychiatry Clin Neurosci 2020 Mar 20;74(3):183-190. Epub 2019 Dec 20.

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China.

Aim: Acupuncture has benefits in the rehabilitation of neuropsychiatric sequelae of stroke. This study was aimed to evaluate the effectiveness of dense cranial electroacupuncture stimulation plus body acupuncture (DCEAS+BA) in treating poststroke depression (PSD), functional disability, and cognitive deterioration.

Methods: In this assessor- and participant-blinded, randomized controlled trial, 91 stroke patients who initially had PSD were randomly assigned to either DCEAS+BA (n = 45) or minimum acupuncture stimulation as controls (n = 46) for three sessions per week over 8 consecutive weeks. Read More

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http://dx.doi.org/10.1111/pcn.12959DOI Listing
March 2020
1.620 Impact Factor

Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?

J Gerontol A Biol Sci Med Sci 2020 Apr;75(5):987-994

Department of Age-Related Healthcare, Tallaght University Hospital, Dublin.

Background: Use of anticholinergic medication is associated with an increased risk of cognitive impairment and/or dementia. Despite this, the impact of continuing medication with anticholinergic properties in those diagnosed with Alzheimer's Disease (AD) is not clear.

Methods: Analysis of data from NILVAD, an 18-month randomized controlled trial of Nilvadipine in AD. Read More

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http://dx.doi.org/10.1093/gerona/glz244DOI Listing
April 2020
1 Read

Examining the validity of the multiple-sclerosis walking scale-12 with Rasch analysis: Results from an Italian study.

Mult Scler Relat Disord 2019 Nov 19;36:101400. Epub 2019 Sep 19.

Department of Rehabilitation, "Mons. L. Novarese" Hospital, Moncrivello (VC), Italy.

Background: The Multiple Sclerosis Walking Scale (MSWS-12) has showed good psychometric properties in reports exploring its validity using Classical Test Theory methods. Findings from recent studies using Item Response Theory methods advance the idea that some aspects of the MSWS-12 does not fully comply with some requirements of sound measurement.

Research Question: The present study investigated whether the measurement properties of the Italian version of the MSWS-12 met the assumptions of the Rasch model. Read More

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http://dx.doi.org/10.1016/j.msard.2019.101400DOI Listing
November 2019
1 Read

Retrograde intramedullary nail fixation compared with fixed-angle plate fixation for fracture of the distal femur: the TrAFFix feasibility RCT.

Health Technol Assess 2019 09;23(51):1-132

Medical Research Council Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton, UK.

Background: Fractures of the distal femur are an increasingly common injury; the optimal management of these injuries remains controversial. The two interventions used in UK practice are intramedullary fixation, with a locked retrograde nail, and extramedullary fixation, with a fixed angle plate.

Objectives: This study assessed the feasibility of a definitive trial and included a process evaluation to understand the generalisability and likely success of a future trial. Read More

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http://dx.doi.org/10.3310/hta23510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778843PMC
September 2019
3 Reads

Effectiveness of the International Symbol of Access and inclusivity of other disability groups.

Disabil Health J 2020 01 5;13(1):100836. Epub 2019 Sep 5.

The University of Alabama at Birmingham, 1720 2nd Avenue South, Birmingham, AL, 35294-1212, United States. Electronic address:

Background: The International Symbol of Access (ISA) is recognized world-wide for designating and identifying areas which are wheelchair accessible, however its meaning has evolved to include both restricted use and universal accessibility.

Objective: This study seeks to investigate the effectiveness of the ISA in representing individuals of all impairment types.

Methods: A mixed-method survey was disseminated in the U. Read More

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http://dx.doi.org/10.1016/j.dhjo.2019.100836DOI Listing
January 2020
1 Read

Development and validation of the Hypersomnia Severity Index (HSI): A measure to assess hypersomnia severity and impairment in psychiatric disorders.

Psychiatry Res 2019 11 31;281:112547. Epub 2019 Aug 31.

Department of Psychology, University of California, Berkeley, CA, United States.

Hypersomnia is common in psychiatric disorders, yet there are few self-report measures that adequately characterize this sleep disturbance. The objective of this study was to validate the Hypersomnia Severity Index (HSI), a tool designed to measure severity, distress and impairment of hypersomnia in psychiatric populations. Psychometric properties were evaluated in an undergraduate Scale Development sample (N = 381) and two psychiatric Scale Validation samples: euthymic bipolar participants with a range of sleep complaints (N = 89), and unmedicated unipolar depressed participants (N = 21) meeting operational criteria for hypersomnolence disorder. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.112547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961815PMC
November 2019
1 Read

The walking estimated limitation stated by history (WELSH): a visual tool to self-reported walking impairment in a predominantly illiterate population.

Cardiovasc J Afr 2019 Aug 30;30:1-6. Epub 2019 Aug 30.

Vascular Medicine, University Hospital Centre of Angers, Angers Cedex Angers, France; UMR CNRS 6214, INSERM 1083, Mitovasc Institute, Angers, France. Email:

Background: The prevalence of cardiovascular diseases is increasing in low-income countries. Various questionnaires to estimate walking capacity in patients are available in multiple languages but they are not suitable for illiterate patients.

Objective: The walking estimated limitation stated by history (WELSH) tool aims at rating individual walking disability using only drawings and four items. Read More

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http://dx.doi.org/10.5830/CVJA-2019-032DOI Listing
August 2019
16 Reads

Effect of Rehabilitation Treatments on Disability in Persons With Disorders of Consciousness: A Propensity Score Study.

Arch Phys Med Rehabil 2020 01 26;101(1):95-105. Epub 2019 Aug 26.

Neurology, Public Health, Disability Unit Scientific Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Objective: To evaluate the effects of rehabilitation (physical and cognitive) treatments on the diagnosis severity and Disability Rating Scale (DRS) scores, adjusted for a number of potential confounders measured at baseline, in a large cohort of patients with disorders of consciousness across time.

Design And Setting: An observational, longitudinal (2 evaluations), multicenter project was made in 90 Italian centers.

Participants: Patients (N=364) with a diagnosis of disorders of consciousness. Read More

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http://dx.doi.org/10.1016/j.apmr.2019.07.010DOI Listing
January 2020
2 Reads

Relationship of cognitive impairment with depressive symptoms and psychosocial function in patients with major depressive disorder: Cross-sectional analysis of baseline data from PERFORM-J.

J Affect Disord 2019 11 30;258:172-178. Epub 2019 Jul 30.

Japan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, Japan.

Background: Evidence is accumulating for the presence of cognitive impairment in patients with major depressive disorder (MDD). The Prospective Epidemiological Research on Functioning Outcomes Related to Major Depressive Disorder in Japan (PERFORM-J) study is a 6-month, non-interventional, prospective, multicenter, epidemiological study. Using baseline data, the relationship between cognitive symptoms and psychosocial function was analyzed in Japanese patients with MDD. Read More

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http://dx.doi.org/10.1016/j.jad.2019.07.064DOI Listing
November 2019
2 Reads

Dual-task interference during hand dexterity is a predictor for activities of daily living performance in Parkinson's disease.

Parkinsonism Relat Disord 2019 09 13;66:100-104. Epub 2019 Jul 13.

Department of Neurology, Faculty of Medicine, Ordu University, Turkey.

Introduction: Dual-task interference (DTI) leads to impairment of hand dexterity in Parkinson's disease (PD). The performance of activities of daily living (ADL) is negatively affected by dexterity in PD. However, the contribution of DTI to dexterity-related ADL disability remains unclear. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2019.07.017DOI Listing
September 2019
3 Reads

Healthcare Provider Issues and Perspective: Impairment Ratings and Disability Determinations.

Phys Med Rehabil Clin N Am 2019 08 29;30(3):511-522. Epub 2019 May 29.

SpineCare & Forensic Medicine, PLLC, 5610 East Grant Road, Tucson, AZ 85712, USA.

Approximately 1 in 4 adults in the United States have a disability that affects major life activities. This article provides a brief historical perspective of disability determination, and revisits the conceptual foundation for understanding the current models of disablement and their general application to the major US disability systems and nuances thereof. The expectations placed on the physician-expert examiner and why the physiatrist is ideally equipped to function in this role are discussed. Read More

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http://dx.doi.org/10.1016/j.pmr.2019.04.001DOI Listing
August 2019
8 Reads

Perception of Stigma and Its Associated Factors Among Patients With Major Depressive Disorder: A Multicenter Survey From an Asian Population.

Front Psychiatry 2019 15;10:321. Epub 2019 May 15.

Institute of Mental Health, Peking University Sixth Hospital, Beijing, China.

Stigma of major depressive disorder (MDD) is an important public health problem. This study aimed to examine the level of perceived stigma and its associated factors in MDD patients in five Asian countries, including China, Korea, Malaysia, Singapore, and Thailand. A total of 547 outpatients with MDD were included from Asian countries. Read More

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http://dx.doi.org/10.3389/fpsyt.2019.00321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529583PMC
May 2019
14 Reads

Cognitive Syndromes and C9orf72 Mutation Are Not Related to Cerebellar Degeneration in Amyotrophic Lateral Sclerosis.

Front Neurosci 2019 10;13:440. Epub 2019 May 10.

Neuroradiology Department, Fondazione IRCCS Istituto Neurologico "Carlo Besta," Milan, Italy.

Objective: The notion that cerebellar pathology may contribute to cognitive impairment in ALS, especially in patients with C9orf72 repeated expansion, has been inconsistently reported. This study aimed exploring the relationship between cerebellar involvement, cognitive impairment and C9orf72 repeated expansion of patients with ALS.

Methods: Quantitative assessment of cerebellar lobules has been investigated in 66 non-demented patients with ALS and 28 healthy controls (HCs). Read More

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http://dx.doi.org/10.3389/fnins.2019.00440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524613PMC
May 2019
10 Reads

Disability as a determinant of fatigue in MS patients.

Arq Neuropsiquiatr 2019 05;77(4):248-253

Universidade Federal de Minas Gerais, Programa de Pós-graduação em Neurociências, Belo Horizonte MG, Brasil.

Introduction: Fatigue is one of the most frequent and disabling symptoms in multiple sclerosis (MS). Central, psychological, and peripheral factors may contribute to the occurrence of fatigue.

Objectives: The current study aimed to evaluate potential fatigue determinants in patients with relapsing-remitting MS with a low functional impairment. Read More

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http://dx.doi.org/10.1590/0004-282X20190035DOI Listing
May 2019
3 Reads

Cognitive Complaints in Nondemented Parkinson's Disease Patients and Their Close Contacts do not Predict Worse Cognitive Outcome.

Alzheimer Dis Assoc Disord 2019 Apr-Jun;33(2):147-153

Division of Neurology, Morton and Gloria Shulman Movement Disorders Center and the Edmond J Safra Program in Parkinson's disease, Toronto Western Hospital, University of Toronto.

Objectives: The main purpose of this study was to investigate 4 methods of eliciting subjective cognitive complaints (SCCs) in Parkinson's disease (PD) patients without dementia and determine the relationship between their SCC and cognitive performance.

Design: This study was a retrospective analysis of a prospective cohort study.

Setting: Six North American movement disorder clinics. Read More

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http://dx.doi.org/10.1097/WAD.0000000000000301DOI Listing
April 2020
10 Reads

Treatment monitoring as a component of psychologically informed physical therapy: A case series of patients at high risk for persistent low back pain related disability.

Musculoskelet Sci Pract 2019 06 19;41:36-42. Epub 2019 Mar 19.

Duke Clinical Research Institute and Department of Orthopaedic Surgery, Duke University, 200 Morris Street, Durham NC 27701, USA. Electronic address:

Background: Psychologically Informed Physical Therapy (PIPT) aims to identify individuals at high risk for transitioning to chronicity and merge impairment-focused physical therapy with cognitive behavioral therapy principles. Treatment monitoring is an important part of PIPT and involves identifying changes in clinical measures to inform clinical decision making.

Objectives: The purpose of this case series is to describe treatment monitoring using psychological and physical impairment measures for patients identified as 'high-risk' for persistent low back pain (LBP) related disability. Read More

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http://dx.doi.org/10.1016/j.msksp.2019.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528824PMC
June 2019
5 Reads

LSVT BIG in late stroke rehabilitation: A single-case experimental design study.

Can J Occup Ther 2019 Apr 12;86(2):87-94. Epub 2019 Mar 12.

Background.: Late stroke rehabilitation interventions often target impairment with limited carryover to daily occupation.

Purpose. Read More

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http://dx.doi.org/10.1177/0008417419832951DOI Listing
April 2019
3 Reads

Exploring the association between Cerebral small-vessel diseases and motor symptoms in Parkinson's disease.

Brain Behav 2019 04 27;9(4):e01219. Epub 2019 Feb 27.

Department of Neurology, Xinhua Hospital, Affiliated to Shanghai JiaoTong University, School of Medicine, Shanghai, China.

Objectives: to explore the association between cerebral small-vessel diseases (CSVDs) and motor symptoms in Parkinson's disease (PD).

Methods: 137 PD patients were recruited into the study. Detailed motor symptoms, including tremor, rigidity, bradykinesia, and axial impairment, were evaluated using Unified Parkinson's disease Rating Scale (UPDRS). Read More

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http://dx.doi.org/10.1002/brb3.1219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456802PMC
April 2019
9 Reads

[Multimodal rheumatologic complex treatment of rheumatoid arthritis-a monocentric retrospective analysis].

Z Rheumatol 2019 Mar;78(2):136-142

Abt. für Rheumatologie, Klinische Immunologie, Osteologie und Physikalische Medizin, Kerckhoff-Klinik GmbH Bad Nauheim, Benekestr. 2-8, 61231, Bad Nauheim, Deutschland.

Background: Multimodal rheumatologic complex treatment (MRCT, operation and procedures classification system, OPS code 8‑983) is a specific concept of acute inpatient care (DRG I97Z) for treatment of patients with rheumatic diseases, degenerative diseases and/or chronic pain syndromes suffering from exacerbated pain and functional impairment.

Objective: A monocentric retrospective analysis of the effects of MRCT on pain and functional status in patients with rheumatoid arthritis (RA) was conducted.

Methods: A total of 103 treatment episodes in 75 patients with proven RA who received MRCT between 2014 and 2017 were included in the analysis. Read More

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http://dx.doi.org/10.1007/s00393-019-0593-zDOI Listing
March 2019
2 Reads

Predictors of pain intensity and Oswestry Disability Index in prolonged standing service workers with nonspecific chronic low back pain subclassified as active extension pattern.

Musculoskelet Sci Pract 2019 04 28;40:58-64. Epub 2019 Jan 28.

234 Maeji-ri, Heungeop-Myeon, Wonju, Kangwon-Do, 220-710, Department of Physical Therapy, Graduate School, Yonsei University, Wonju, South Korea. Electronic address:

Background: Because patients with nonspecific chronic low back pain (NSCLBP) are heterogeneous, subgrouping patients with NSCLBP might clarify the research findings. NSCLBP in the direction of extension movement, namely active extension pattern (AEP), is common during prolonged standing.

Objective: Predictors of pain intensity and dysfunction were determined in prolonged standing service workers (PSSWs) with NSCLBP subclassified as AEP in the motor impairment subgroup. Read More

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http://dx.doi.org/10.1016/j.msksp.2019.01.014DOI Listing
April 2019
27 Reads

Impact of Nutritional Status on Caregiver Burden of Elderly Outpatients. A Cross-Sectional Study.

Nutrients 2019 Jan 28;11(2). Epub 2019 Jan 28.

Geriatric Clinic Unit, Geriatric-Rehabilitation Department, Azienda Ospedaliero-Universitaria di Parma, 43126 Parma, Italy.

The assistance to older community-dwellers provided by family caregivers is crucial for the maintenance of an acceptable quality of life, especially when dementia is present. The caregiver burden may be extremely high, but few data are available on what patient domains mainly affect the caregiver. The aim of this cross-sectional study, performed in older outpatients, was to examine the impact of cognitive, physical and nutritional status of elderly community-dwellers on the caregiver burden, as evaluated by the Caregiver Burden Inventory (CBI). Read More

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http://dx.doi.org/10.3390/nu11020281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412930PMC
January 2019
11 Reads

Efficacy and Safety of Deep Brain Stimulation in the Treatment of Parkinson's Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Cureus 2018 Oct 22;10(10):e3474. Epub 2018 Oct 22.

Pharmacology, Imperial College London, London, GBR.

Deep brain stimulation (DBS) is a neurosurgical procedure indicated for patients with advanced Parkinson's disease (PD). Whether similar benefits may be realized by patients with early PD, however, is currently unclear, especially given the potential risks of the procedure. This systematic review and meta-analysis aimed to investigate the relative efficacy and safety of DBS in comparison to best medical therapy (BMT) in the treatment of PD. Read More

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http://dx.doi.org/10.7759/cureus.3474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318091PMC
October 2018
40 Reads

Sex-Differences in the Pattern of Comorbidities, Functional Independence, and Mortality in Elderly Inpatients: Evidence from the RePoSI Register.

J Clin Med 2019 Jan 12;8(1). Epub 2019 Jan 12.

Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro 88100, Italy.

Background: The RePoSi study has provided data on comorbidities, polypharmacy, and sex dimorphism in hospitalised elderly patients.

Methods: We retrospectively analysed data collected from the 2010, 2012, 2014, and 2016 data sets of the RePoSi register. The aim of this study was to explore the sex-differences and to validate the multivariate model in the entire dataset with an expanded follow-up at 1 year. Read More

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http://dx.doi.org/10.3390/jcm8010081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352226PMC
January 2019
11 Reads

Distribution of depression, somatization and pain-related impairment in patients with chronic temporomandibular disorders.

J Appl Oral Sci 2019 Jan 7;27:e20180210. Epub 2019 Jan 7.

Università di Siena, Scuola di Odontoiatria, Siena, Italia.

Objective: the aim of this study was to describe the frequency of psychosocial diagnoses in a large sample of patients attending a tertiary clinic for treatment of temporomandibular disorders (TMD).

Material And Methods: six hundred and ninety-one patients who sought treatment for pain-related TMD were selected. Chronic pain-related disability (Graded Chronic Pain Scale, GCPS), depression [Symptoms Checklist-90 (SCL-90) scale for depression, DEP] and somatization levels (SCL-90 scale for non-specific physical symptoms, SOM) were evaluated through the Research Diagnostic Criteria for TMD (RDC/TMD) Axis II psychosocial assessment; TMD diagnoses were based on the Axis I criteria. Read More

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http://dx.doi.org/10.1590/1678-7757-2018-0210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322638PMC
January 2019
25 Reads

Trait Anxiety as a Mediator of the Association between Attention Deficit Hyperactivity Disorder Symptom Severity and Functional Impairment.

Clin Psychopharmacol Neurosci 2018 Nov;16(4):407-414

Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Objective: Anxiety has been shown to influence functional impairment in patients with attention deficit hyperactivity disorder (ADHD). This study aimed to compare functional impairment in subjects with and without adult ADHD and to investigate the associations among trait anxiety, functional impairment, and ADHD symptom severity. Moreover, the effects of ADHD symptom subtypes on trait anxiety and functional impairment were also examined. Read More

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http://dx.doi.org/10.9758/cpn.2018.16.4.407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245288PMC
November 2018
20 Reads

Electrical dry needling as an adjunct to exercise, manual therapy and ultrasound for plantar fasciitis: A multi-center randomized clinical trial.

PLoS One 2018 31;13(10):e0205405. Epub 2018 Oct 31.

Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, Spain.

Study Design: Randomized, single-blinded, multi-center, parallel-group trial.

Objectives: To compare the effects of adding electrical dry needling into a program of manual therapy, exercise and ultrasound on pain, function and related-disability in individuals with plantar fasciitis (PF).

Background: The isolated application of electrical dry needling, manual therapy, exercise, and ultrasound has been found to be effective for PF. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205405PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209187PMC
March 2019
61 Reads

Clinical characteristics and quality of life in Chinese patients with multiple system atrophy.

Brain Behav 2018 12 30;8(12):e01135. Epub 2018 Oct 30.

Department of Neurology & The Collaborative Innovation Center for Brain Science, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Objectives: Multiple system atrophy (MSA) is a progressive neurodegenerative disorder that causes early sustained disability and poor health-related quality of life (HrQoL). The clinical features and their effects on the HrQoL of patients in China have received little attention in the research literature. We evaluated the clinical characteristics and HrQoL of Chinese patients with MSA. Read More

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http://dx.doi.org/10.1002/brb3.1135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305933PMC
December 2018
16 Reads

A randomised controlled trial of long-chain omega-3 polyunsaturated fatty acids in the management of rotator cuff related shoulder pain.

BMJ Open Sport Exerc Med 2018 19;4(1):e000414. Epub 2018 Oct 19.

School of Health and Social Work, University of Hertfordshire, Hatfield, UK.

Study Design: Multicentre, double-blind, placebo-controlled randomised clinical trial.

Objectives: To compare the effectiveness of long chain omega-3 polyunsaturated fatty acids (PUFAs) as part of the management for people diagnosed with rotator cuff related shoulder pain (RCRSP).

Summary Of Background: Although there is no robust evidence to support their use, omega-3 PUFAs have been recommended for those with tendinopathy due to their potential to moderate inflammation. Read More

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http://bmjopensem.bmj.com/lookup/doi/10.1136/bmjsem-2018-000
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http://dx.doi.org/10.1136/bmjsem-2018-000414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196970PMC
October 2018
19 Reads

Long-term outcomes of adolescents with juvenile-onset fibromyalgia into adulthood and impact of depressive symptoms on functioning over time.

Pain 2019 Feb;160(2):433-441

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.

Juvenile-onset fibromyalgia (JFM) is typically diagnosed in adolescence and characterized by widespread pain and marked functional impairment. The long-term impact of JFM into adulthood is poorly understood. The objectives of this study were to describe physical and psychosocial outcomes of youth diagnosed with JFM in early adulthood (∼8-year follow-up), examine longitudinal trajectories of pain and depressive symptoms from adolescence to young adulthood, and examine the impact of pain and depressive symptoms on physical functioning over time. Read More

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http://Insights.ovid.com/crossref?an=00006396-900000000-9883
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http://dx.doi.org/10.1097/j.pain.0000000000001415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344278PMC
February 2019
10 Reads

Validation of a performance-based assessment of cognitive functional ability in Parkinson's disease.

Mov Disord 2018 11 10;33(11):1760-1768. Epub 2018 Oct 10.

Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Background: Outcome measures that capture functional abilities related to cognition offer the potential to demonstrate real-world effectiveness of cognitive-enhancing treatments. However, distinguishing functional disability related to cognition from that attributed to motor symptoms can be difficult in PD. A performance-based functional assessment allows for direct observation of activity of daily living skills and separation of cognitive from motoric disabilities. Read More

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http://dx.doi.org/10.1002/mds.27487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261681PMC
November 2018
39 Reads

Meaningful Change Estimates for the Late-Life Function and Disability Instrument in Older Adults.

J Gerontol A Biol Sci Med Sci 2019 03;74(4):556-559

New England Geriatric Research Education and Clinical Center, Veterans Administration Boston Health System, Massachusetts.

Background: The Late-Life Function and Disability Instrument (LLFDI) is a well-validated and frequently used patient-reported outcome for older adults. The aim of this study was to estimate the minimal clinically important difference (MCID) of the LLFDI-Function Component (LLFDI-FC) and its subscales among community-dwelling older adults with mobility limitations.

Methods: We performed a secondary analysis of the Boston Rehabilitative Impairment Study of the Elderly, a longitudinal cohort study of older adults with mobility limitations residing in the community. Read More

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/gly230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417450PMC
March 2019
13 Reads

Use of F-sodium fluoride bone PET for disability evaluation in ankle trauma: a pilot study.

BMC Med Imaging 2018 09 20;18(1):34. Epub 2018 Sep 20.

Division of PM&R, Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, 94063, USA.

Background: There are no objective and accurate rating tools for permanent impairment of traumatized ankles. The purpose of this study is to assess the role of 18F-Sodium fluoride (18F-NaF) positron emission tomography-computed tomography (PET/CT) bone scans in evaluating patients with limited ankle range of motion (ROM) after trauma.

Methods: 18F-NaF PET/CT was performed in 121 patients (75 men, 46 women; mean age: 45. Read More

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http://dx.doi.org/10.1186/s12880-018-0277-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149075PMC
September 2018
12 Reads

Measuring the Impact of Tinnitus on Aided Listening Effort Using Pupillary Response.

Trends Hear 2018 Jan-Dec;22:2331216518795340

5 Eriksholm Research Centre, Snekkersten, Denmark.

Tinnitus can have serious impact on a person's life and is a common auditory symptom that is especially comorbid with hearing loss. This study investigated processing effort required for speech recognition in a group of hearing-impaired people with tinnitus and a control group (CG) of hearing-impaired people without tinnitus by means of pupillary response. Furthermore, the relationship between the pupillary response, self-rating measures of tinnitus severity, and fatigue was examined. Read More

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http://dx.doi.org/10.1177/2331216518795340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136111PMC
February 2019
32 Reads

Invariance of parent ratings of attention deficit hyperactivity disorder symptoms for children with and without intellectual disability.

J Appl Res Intellect Disabil 2019 Mar 29;32(2):288-299. Epub 2018 Aug 29.

Department of Psychology & Research Institute on Health Sciences, University of Balearic Islands, Palma de Mallorca, Spain.

Background: Although attention deficit hyperactivity disorder (ADHD) is considered a valid diagnosis for children with intellectual disability, no studies have evaluated the invariance of ADHD symptom ratings across children with and without intellectual disability.

Method: Parents completed ratings on the ADHD symptoms for 189 children with intellectual disability and for 474 children without intellectual disability. Differential item functioning analysis was used to determine the equivalence of the ADHD symptoms across the two groups. Read More

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http://dx.doi.org/10.1111/jar.12525DOI Listing
March 2019
7 Reads

The impact of urinary incontinence on the quality of life and on the sexuality of patients with HAM/TSP.

Braz J Infect Dis 2018 Jul - Aug;22(4):288-293. Epub 2018 Aug 24.

Instituto de Infectologia Emilio Ribas, Coordenação de Neurologia, São Paulo, SP, Brazil.

This study evaluated the impact of urinary incontinence (UI) on sexuality, body image, mood, and quality of life of patients with myyelopathy associated with HTLV-1/tropical spastic paraparesis (HAM/TSP). The sample consisted of 31 HAM/TSP outpatients, of both sexes, followed-up at the Emílio Ribas Infectology Institute. The following instruments were used: sociodemographic questionnaire, Hospital Anxiety and Depression Scale (HAD), Body Image Assessment Scale, Sexual Quotient Female (QS-F) and Male (QS-M) Versions, King's Health Questionnaire (KHQ), and Revised OSAME Motor Disability Score. Read More

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http://dx.doi.org/10.1016/j.bjid.2018.07.003DOI Listing
October 2018
22 Reads

Osteoarthritis of knee joint in metabolic syndrome.

Clin Rheumatol 2018 Oct 23;37(10):2855-2861. Epub 2018 Jul 23.

Faculty of Medicine, Department of clinical pathology, Mansoura University, Mansoura, Egypt.

Pathogenesis of osteoarthritis may have a systemic metabolic component. This study was undertaken to assess the prevalence of primary knee osteoarthritis (OA) in a sample of Egyptian patients with metabolic syndrome (MetS) and to examine the relationship of metabolic syndrome and its components with clinical, functional, and radiographic findings of knee OA. A total of 60 patients (55 females, 5 males) diagnosed as having MetS according to the National Cholesterol Education Program Adult Treatment Panel III (ATP III) criteria and 30 obese subjects without MetS (24 females, 6 males), serving as a control group, were included in this study. Read More

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http://dx.doi.org/10.1007/s10067-018-4201-4DOI Listing
October 2018
31 Reads

Sense of autonomy and daily and scholastic functioning among children with cerebral palsy.

Res Dev Disabil 2018 Sep 18;80:161-169. Epub 2018 Jul 18.

The Edmond and Lily Safra Children's Hospital, The Chaim Sheba Medical Center, Ramat Gan, Israel.

Background: There is growing evidence that children's sense of autonomy is an important psychological need closely linked with the development of self-esteem and motivation. Among children with physical disabilities, motor or cognitive limitations may negatively affect child's sense of autonomy (CSA) and competency.

Purpose: To examine how sense of autonomy among children with cerebral palsy (CP) directly and indirectly relates to their activity of daily living (ADL) and scholastic performance. Read More

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http://dx.doi.org/10.1016/j.ridd.2018.06.006DOI Listing
September 2018
60 Reads

Extrapyramidal deficits in ALS: a combined biomechanical and neuroimaging study.

J Neurol 2018 Sep 11;265(9):2125-2136. Epub 2018 Jul 11.

Laboratoire CeRSM - EA 2931 Paris Ouest, Nanterre, France.

Introduction: Extrapyramidal deficits are poorly characterised in amyotrophic lateral sclerosis (ALS) despite their contribution to functional disability, increased fall risk and their quality-of-life implications. Given the concomitant pyramidal and cerebellar degeneration in ALS, the clinical assessment of extrapyramidal features is particularly challenging.

Objective: The comprehensive characterisation of postural instability in ALS using standardised clinical assessments, gait analyses and computational neuroimaging tools in a prospective study design. Read More

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http://dx.doi.org/10.1007/s00415-018-8964-yDOI Listing
September 2018
19 Reads

An Evaluation of the World Health Organization and American Medical Association Ratings of Hearing Impairment and Simulated Single-Sided Deafness.

J Am Acad Audiol 2018 Jul/Aug;29(7):634-647

Department of Biostatistics, East Carolina University, Greenville, NC.

Background: According to the World Health Organization (WHO), a pure-tone threshold average (PTA) ≤25 dB HL for the better ear represents "no impairment." This implies that patients with single-sided deafness (SSD) would have "no or very slight hearing problems." According to the American Medical Association (AMA), a patient with SSD would receive a binaural hearing impairment rating of 16. Read More

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http://dx.doi.org/10.3766/jaaa.17034DOI Listing
October 2019
2 Reads

Beyond 35 years of Parkinson's disease: a comprehensive clinical and instrumental assessment.

J Neurol 2018 Sep 26;265(9):1989-1997. Epub 2018 Jun 26.

Department of Neuroscience "Rita Levi Montalcini", University of Turin, Via Cherasco 15, 10124, Turin, Italy.

Background: We sought to characterize the clinical, neuropsychological, electrophysiological, and neuroimaging features of Parkinson's disease (PD) after over 35 years since the onset of motor symptoms.

Methods: Five consecutively consenting PD patients treated with subthalamic nucleus deep brain stimulation (STN-DBS) were recruited in a cross-sectional study of motor (Unified PD Rating Scale section-III), non-motor (Non-Motor Symptoms Scale), autonomic (Scale for Outcome in PD-Autonomic), and neuropsychological features associated with the very advanced phase of PD. In addition, patients underwent neurophysiological (autonomic tests and nerve conduction studies) and neuroimaging (brain MRI, I-FP-CIT SPECT, and I-MIBG myocardial scintigraphy) studies, as well as a genetic analysis of 34 genes and single nucleotide polymorphisms associated with PD. Read More

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http://dx.doi.org/10.1007/s00415-018-8955-zDOI Listing
September 2018
13 Reads