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Insights Imaging 2019 Mar 4;10(1):29. Epub 2019 Mar 4.

University of Rochester Medical Center, Rochester, USA.

Paragangliomas arise from paraganglion cells which serve varied regulatory tasks in the body. When these cells demonstrate neoplasia within the head and neck, they typically present in characteristic locations including the carotid space, the jugular foramen, the middle ear, and along the course of the vagus nerve. The goal of this article is to review the relevant anatomy related to head and neck paragangliomas, as well as their typical imaging characteristics on cross-sectional imaging including CT, MR, ultrasound, and nuclear medicine studies. Read More

Laryngoscope 2019 Jan 8;129(1):67-75. Epub 2018 Sep 8.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.

Objectives/hypothesis: Pathologic involvement of the inferior cochlear vein is a mechanism of sensorineural hearing loss in patients with jugular foramen paraganglioma.

Study Design: Retrospective case-control study.

Methods: The presenting audiograms, magnetic resonance imaging, and computed tomography were reviewed in 46 subjects with jugular foramen paragangliomas. Read More

Orv Hetil 2018 Sep;159(36):1487-1492

Fül-Orr-Gégészeti és Fej-Nyaksebészeti Osztály, Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház Miskolc, Szentpéteri kapu 72-76., 3526.

Our goal was to report a 44-year-old woman with carotid body tumor, and to give a brief and comprehensive presentation about the disease and summarize its complex management. Carotid body tumor is a rare, mostly sporadic, benign head and neck mass originating from the glomus caroticum. It occurs mostly in middle-aged women as a slowly growing, semifix, painless neck mass. Read More

Otol Neurotol 2018 Oct;39(9):1079-1087

West Virginia University Department of Otolaryngology - Head and Neck Surgery, Morgantown, West Virginia.

Objective: 1) Determine tumor control, symptomatic control, and complication rates of primary radiosurgery (PRS) for treatment of glomus jugulare tumors (GJTs) via systematic review and meta-analysis. 2) Identify risk factors for these outcomes.

Data Sources: 1) Search of English articles in PubMed, Web of Science, Cochrane, and EBSCOhost databases from January 1950 to August 2017. Read More

BMJ Case Rep 2018 Jul 3;2018. Epub 2018 Jul 3.

Oral and Maxillofacial Surgery, Royal United Hospital Bath NHS Trust, Bath, UK.

The glomus tumour is a rare neoplasm derived from the glomus apparatus. Subungual sites are most common with only three published cases involving the dorsal tongue. To our knowledge, this is the first case of an intraoral malignant glomus tumour (glomangiosarcoma) to be published in English literature. Read More

Laryngoscope Investig Otolaryngol 2017 12 11;2(6):380-389. Epub 2017 Nov 11.

Department of Otolaryngology-Head and Neck Surgery Kresge Hearing Research Institute Ann Arbor Michigan U.S.A.

Objectives: Paragangliomas of the head and neck and cranial base are typically benign, slow-growing tumors arising within the jugular foramen, middle ear, carotid bifurcation, or vagus nerve proper. The objective of this study was to provide a comprehensive characterization of our institutional experience with clinical management of these tumors and posit an algorithm for diagnostic evaluation and treatment.

Methods: This was a retrospective cohort study of patients undergoing treatment for paragangliomas of the head and neck and cranial base at our institution from 2000-2017. Read More

Clin Nucl Med 2017 Oct;42(10):758-760

From the *Clinical Department of Nuclear Medicine, and †Clinical Department of Radiology, Clinical Hospital Centre Rijeka, Krešimirova 42, Rijeka, Croatia.

A 54-year-old woman was referred to thyroid evaluation because of a lump on the left side of the neck. Ultrasound exam did not show any thyroid abnormality, but highly perfused nodule at the left common carotid artery bifurcation was found. Because of the specific location, somatostatin receptor scintigraphy with Tc EDDA HYNIC-TOC was performed, starting with perfusion images and followed with SPECT/CT imaging at 2 and 4 hours. Read More

Pan Afr Med J 2017;26:241. Epub 2017 Apr 27.

Department of Otorhinolaryngology-Head and Neck Surgery, Military Hospital Meknes, Morocco.

Ann Otol Rhinol Laryngol 2017 Aug 1;126(8):615-618. Epub 2017 Jul 1.

3 Department of Head and Neck Surgery, Florida Hospital Celebration Health, Celebration, Florida, USA.

Objective: The entity of primary mandibular paraganglioma (PGL) is not well accepted within the head and neck. Mandibular PGLs hitherto reported in literature are malignant metastatic lesions, mostly from a pheochromocytoma.

Methods: We report a case of mandibular lytic lesion in a young female with multifocal PGLs but no family history of PGLs. Read More

Ann Otol Rhinol Laryngol 2017 Aug 10;126(8):606-610. Epub 2017 Jun 10.

1 Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Utah, Salt Lake City, Utah, USA.

Objectives: To describe a case of metastatic renal cell carcinoma (RCC) masquerading as a jugular foramen paraganglioma (JP). To compare imaging findings between skull base metastatic RCC and histologically proven paraganglioma.

Methods: A case of unexpected metastatic skull base RCC is reviewed. Read More

Case Rep Neurol 2017 Jan-Apr;9(1):54-61. Epub 2017 Apr 3.

Department of Medicine, Bronx Lebanon Hospital Center, Bronx, NY, USA.

Cranial nerve palsy could be one of the presenting features of underlying benign or malignant tumors of the head and neck. The tumor can involve the cranial nerves by local compression, direct infiltration or by paraneoplastic process. Cranial nerve involvement depends on the anatomical course of the cranial nerve and the site of the tumor. Read More

Asia Pac J Clin Oncol 2018 Apr 24;14(2):e3-e7. Epub 2017 May 24.

Department of Radiation Oncology, Acibadem University, Istanbul, Turkey.

Aim: CyberKnife is a robotic stereotactic radiotherapy system. The aim of this study is to evaluate the effectiveness and the safety of CyberKnife on treating head and neck paragangliomas and to report our results.

Methods: Between March 2009 and June 2014, 12 patients with head and neck paragangliomas have been referred to our clinic: in three cases had jugular paragangliomas, five cases had carotid body paragangliomas and three cases had tympanic paragangliomas. Read More

World Neurosurg 2017 Aug 9;104:14-23. Epub 2017 May 9.

Department of Neurosurgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Objective: Dumbbell-shaped jugular foramen tumors (DSJFTs) extending to the neck present diagnostic and management difficulties because of their rarity, various pathologies, and multidisciplinary involvement. Accurate imaging findings are of great importance for surgical planning and clinical outcomes. However, few articles have discussed this issue to date. Read More

J Craniofac Surg 2017 May;28(3):e271-e273

*Department of Otorhinolaryngology, Head and Neck Surgery, Istanbul Medical Faculty, University of Istanbul †Department of Pathology, Istanbul Medical Faculty, University of Istanbul, Istanbul, Turkey.

Cervical metastases from breast carcinoma are extremely rare after several years of disease-free survival. In this article, a metastatic tumor of the neck originating from a breast carcinoma, which has been treated 14 years ago, is discussed. A case is presented of a 48-year-old female patient with a history of breast carcinoma, which was surgically treated approximately 14 years ago. Read More

J Ultrasound 2017 Mar 13;20(1):73-79. Epub 2017 Jan 13.

Department of Pathology, University College of Medical Sciences (University of Delhi) and GTB Hospital, Dilshad Garden, Delhi, 110095 India.

Vagal paragangliomas are rare benign tumors accounting for only 3% of head and neck paragangliomas and arise from vagal ganglions, predominately the nodose ganglion in the carotid sheath. Imaging plays an important role in their diagnosis, differentiation from more common lesions presenting in the carotid space, and management. MRI is the method of choice for investigation when paragangliomas are clinically suspected. Read More

Laryngoscope 2017 12 14;127(12):2873-2882. Epub 2017 Mar 14.

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, U.S.A.

Objectives/hypothesis: To describe our current multidisciplinary approach to pediatric malignant glomus tumors of the head and neck and review the current literature.

Study Design: Retrospective chart review at a tertiary referral children's hospital and a comprehensive literature review.

Methods: A comprehensive literature search of PubMed, Embase, Web of Science, Google Scholar, and EBSCO with respect to malignant glomus tumors of the head and neck was conducted. Read More

World Neurosurg 2017 May 27;101:559-567. Epub 2017 Feb 27.

Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA; Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA. Electronic address:

Background: Carotid body paragangliomas are rare, usually benign, tumors arising from glomus cells of the carotid body. Bilateral involvement is present in ∼5% of sporadic cases and up to one third of familial cases. In most patients undergoing bilateral resection of carotid body tumors, a condition known as baroreflex failure syndrome (BFS) develops after resection of the second tumor characterized by headache, anxiety, emotional lability, orthostatic lightheadedness, hypertension, and tachycardia. Read More

Am J Otolaryngol 2017 Jan - Feb;38(1):100-102. Epub 2016 Sep 28.

Otolaryngology-Head and Neck Surgery, Eastern Virginia Medical School, 600 Gresham Drive Suite 1100, VA, Norfolk, VA, United States.

Cholesterol granuloma (CG) is the most common benign lesion of the petrous apex, however, it can grow significantly large and become destructive causing a diagnostic dilemma. This case presents a 25-year-old female with 2-year history of left-sided progressive and profound hearing loss, a transient left-sided facial paralysis and cranial nerve 10 palsy who presented with a blue middle ear mass. Her diagnosis did not become apparent until direct visualization intraoperatively. Read More

Clin Nucl Med 2017 Feb;42(2):135-137

From the Departments of *Nuclear Medicine, †Clinical Radiology-Neuroradiology, and ‡Otorhinolaryngology, Head and Neck Surgery, University Hospital Münster, Münster, Germany.

A 60-year-old woman was referred to contrast-enhanced CT for evaluation of jugular vein thrombosis incidentally detected by ultrasound. Contrast-enhanced CT showed an enhanced tumor of the right skull base highly suspicious of jugulotympanic paraganglioma. However, the jugular veins showed a nearly symmetric contrast enhancement without clear evidence of thrombosis. Read More

Eur Arch Otorhinolaryngol 2017 Jan 5;274(1):389-397. Epub 2016 Jul 5.

Head and Neck Centre, Otorhinolaryngology, Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 4, 00029, Helsinki, HUS, Finland.

Treatment of jugulotympanic paragangliomas (JTPGLs) remains challenging with no clear guidelines for management or follow-up. The aim of this retrospective case-note study was to assess long-term results of operatively and conservatively managed JTPGLs between years 1974-2013. A total of 36 patients with JTPGLs were identified. Read More

JAMA Otolaryngol Head Neck Surg 2017 01;143(1):87-88

Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, California.

Ann Emerg Med 2016 Jul;68(1):e9-e10

Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Am J Otolaryngol 2016 May-Jun;37(3):255-8. Epub 2016 Feb 2.

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN. Electronic address:

Objective: To evaluate radiographic tumor control and treatment-related toxicity in glomus jugulare tumors treated with stereotactic radiosurgery (SRS).

Study Design: Retrospective chart review.

Setting: Tertiary academic referral center. Read More

Am J Clin Oncol 2018 03;41(3):223-226

Neurosurgery, University of Florida College of Medicine, Gainesville, FL.

Objectives: To determine the long-term outcome after stereotactic radiosurgery (SRS) for temporal bone paragangliomas.

Materials And Methods: We retrospectively reviewed the medical records of 11 patients with temporal bone paragangliomas (10 patients with a glomus jugulare tumor and 1 patient with a glomus tympanicum tumor) treated between January 1997 and July 2012 at the University of Florida with SRS to a median dose of 15 Gy in 1 fraction. Ten previously unirradiated patients received SRS as did 1 patient who received prior fractionated radiotherapy (FRT) and then received salvage SRS for a local recurrence. Read More

Clin Nucl Med 2016 Feb;41(2):150-2

From the Departments of *Nuclear Medicine and PET, and †ENT, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Metastatic jugular paraganglioma are rare tumors and account for less than 1% of the cases of head and neck tumors. We report a 40-year-old woman of jugular paraganglioma, presenting with right-sided neck swelling, hearing loss, and pulsatile tinnitus. Contrast-enhanced CT temporal bone revealed a mass in the right jugular foramina and extending inferiorly to internal jugular vein. Read More

Head Neck 2016 06 28;38(6):899-905. Epub 2015 Nov 28.

Department of Otology and Skull Base Surgery, Gruppo Otologico, Piacenza-Rome, Italy.

Background: Management of the cervical and petrous internal carotid artery (ICA) is frequently required in Fisch class C tympanojugular paragangliomas (TJPs). The purpose of this study was to discuss the perioperative intervention of the ICA in patients who underwent surgical resection of a TJP.

Methods: A retrospective study of 237 patients surgically treated for Fisch class C TJPs was done to identify cases that required ICA management. Read More

Head Neck 2016 06 7;38(6):871-85. Epub 2015 Sep 7.

Department of Otology and Skull Base Surgery, Gruppo Otologico, Piacenza, Rome, Italy.

Background: The purpose of this study was to share our review of surgical strategies and long-term outcomes in the management of tympanojugular paragangliomas.

Methods: This was a retrospective study with a literature review. The records of 184 patients with 185 tympanojugular paragangliomas were analyzed for tumor class, surgical procedure, preoperative vascular management, and perioperative sequelae. Read More

J Neurol Surg B Skull Base 2015 Aug 12;76(4):249-51. Epub 2015 Mar 12.

Section of Neuroradiology, Department of Radiology, University of California Davis Medical Center, Sacramento, California, United States.

Objectives To evaluate angiographic patterns that may predict the success or failure of carotid artery balloon test occlusion (BTO) and single-photon emission computed tomography (SPECT) analysis for carotid sacrifice. Study Design This is a retrospective nonrandomized study. Study Setting Conducted at the University of California Davis Medical Center, Sacramento, California. Read More

Kulak Burun Bogaz Ihtis Derg 2015 ;25(4):232-6

Department of Otolaryngology, Anadolu Medical Center, 41400 Gebze, Kocaeli, Turkey.

Paragangliomas of the head and neck are usually benign tumors. Malignant form is quite rare and criteria for malignancy are not clear. Clinical, biochemical and histological features of malignant forms are not sufficient to reliably distinguish them from benign tumors and malignancy is established only in the presence of distant metastasis. Read More

Head Neck 2016 Feb 15;38(2):267-76. Epub 2015 Jun 15.

Ear, Nose, and Throat Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Background: The purpose of this study was to reflect our experience in the management of multicentric head and neck paragangliomas, including genetic study and counseling, diagnostic tools, types of treatment, and the need for monitoring.

Methods: A retrospective review of 24 patients with multicentric paraganglioma, including a total of 60 paragangliomas: 37 carotid body tumors, 13 jugulotympanic paragangliomas, and 10 vagal paragangliomas.

Results: A total of 26 surgical procedures were performed, including the resection of 36 paragangliomas. Read More

Rofo 2015 Jun 27;187(6):409-14. Epub 2015 May 27.

Otolaryngol Clin North Am 2015 Jun 11;48(3):515-26. Epub 2015 Apr 11.

Department of Neurologic Surgery, Mayo Clinic School of Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA; Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address:

Gamma Knife stereotactic radiosurgery (GKS) has become an important management strategy for an increasing number of patients with skull base tumors. For select patients with lateral skull base disorders, given the proximity to sensitive critical structures such as the brainstem, cranial nerves, and cochlea, this technology has emerged as a first-line treatment to achieve the paramount goals of long-term tumor control and maintenance of existing neurologic function. This article reviews the indications, technique, and results of GKS for the treatment of vestibular schwannoma and glomus jugulare tumors, and highlights our experience in treating these tumors at the Mayo Clinic. Read More

Rev Esp Med Nucl Imagen Mol 2015 Sep-Oct;34(5):321-4. Epub 2015 Apr 6.

Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.

Head and neck paragangliomas are rare neuroendocrine tumors expressing somatostatin receptors on their cell surface, particularly subtype 2. Due to this distinctive feature, images can be obtained in Nuclear Medicine using synthetic analogues of somatostatin, mainly octreotide, which allow selective display by planar scintigraphy, SPECT-CT or PET-CT imaging after radiolabeling with (111)In or (68)Ga. Three cases have been selected and presented from a series of patients that illustrate the utility of SPECT-CT studies with (111)In-octreotide in the diagnosis and monitoring of this type of tumor. Read More

Eur J Nucl Med Mol Imaging 2015 Jul 31;42(8):1223-30. Epub 2015 Mar 31.

THERANOSTICS Centre for Molecular Radiotherapy and Molecular Imaging, ENETS Center of Excellence, Zentralklinik Bad Berka, Robert Koch Allee, Bad Berka, 99437, Germany.

Purpose: Head and neck paragangliomas (HNPGLs) are rare tumours arising from autonomic nervous system ganglia. Although surgery offers the best chance of complete cure, there is associated morbidity due to the crucial location of these tumours. Radiotherapy arrests tumour growth and provides symptomatic improvement, but has long-term consequences. Read More

Otolaryngol Clin North Am 2015 Apr;48(2):331-41

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA.

Jugular paragangliomas are generally benign slow-growing tumors that can cause pulsatile tinnitus, hearing loss, and cranial nerves neuropathy. Progressive growth can also lead to intracranial extension. Historically, the treatment of choice for these lesions has been gross total resection. Read More

Otolaryngol Clin North Am 2015 Apr 4;48(2):293-304. Epub 2015 Feb 4.

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Nashville, TN 37232, USA.

Glomus tympanicum (GT) tumors are benign arising from paraganglion cells of the tympanic plexus in the middle ear. Although surgical resection remains the best option for definitive treatment of these tumors, the diagnostic and management algorithms have evolved considerably with the introduction of high-resolution computed tomography, MRI, and genetic testing. Read More

Turk Neurosurg 2015 ;25(1):162-7

Umraniye Teaching and Research Hospital, Department of Neurosurgery, Istanbul, Turkey.

Paraganglioma (PG) is a rare tumor of the dispersed neuroendocrine system. PG derives from the embryonic sympathetic and parasympathetic nervous system. Paraganglioma is a neoplasm of the dispersed neuroendocrine system that affects a variety of anatomic sites, mainly the head and neck. Read More

Radiol Clin North Am 2015 Jan 5;53(1):197-213. Epub 2014 Oct 5.

Department of Radiology, University of Michigan Health System, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address:

The diagnosis of vascular lesions of the head and neck should be directed by classifying the lesions as tumors or malformations and by determining their flow characteristics. Location of the lesion is key when differentiating between vascular neoplasms. Ultrasonography is an appropriate screening tool; MRI is often used to confirm the diagnosis. Read More

Otolaryngol Head Neck Surg 2015 Jan 31;152(1):98-105. Epub 2014 Oct 31.

The Otology Group of Vanderbilt, Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Objective: To characterize clinical disease progression and radiologic growth in a series of observed, previously untreated, glomus jugulare tumors (GJT).

Study Design: Retrospective review.

Setting: Tertiary neurotologic referral center. Read More

Otolaryngol Head Neck Surg 2014 Dec 26;151(6):991-5. Epub 2014 Sep 26.

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Objectives: To evaluate tumor control following subtotal resection of advanced jugular paragangliomas in patients with functional lower cranial nerves and to investigate the utility of salvage radiotherapy for residual progressive disease.

Study Design: Case series with planned chart review.

Setting: Tertiary academic referral center. Read More

Rev Esp Med Nucl Imagen Mol 2014 Nov-Dec;33(6):374-7. Epub 2014 Jul 17.

Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

Paragangliomas, or glomus tumors, are neoplasms arising from extra-adrenal chromaffin tissue. They frequently cause symptoms by over-production of catecholamines with known predilection to multicentricity. We describe the case of a patient with bilateral carotid body tumor who underwent a preoperative ⁶⁸Gallium labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-Octreotide (⁶⁸Ga-DOTANOC) positron emission tomography/computed tomography (PET/CT) imaging for staging. Read More

Clin Imaging 2014 Sep-Oct;38(5):655-8. Epub 2014 Jun 19.

Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, 600 N. Wolfe Street, Baltimore, MD 21287.

The aim of this retrospective study is to assess the rate at which glomus jugulare tumors invade the hypoglossal canal (HC) and to correlate computed tomography (CT) and magnetic resonance imaging (MRI) findings with the clinical evidence of cranial nerve (CN) XII dysfunction. CT and MRI imaging modalities of 31 patients were blindly reviewed by an attending neuroradiologist. Imaging studies identified involvement in 22 tumors (22/31, 71. Read More

Diagn Interv Radiol 2014 Sep-Oct;20(5):432-7

Department of Radiology, Salihli State Hospital, Manisa, Turkey.

Vascular lesions of the head and neck include vascular neoplasms, vascular malformations, and hypervascular lesions, derived from nonvascular soft-tissue elements. We retrospectively evaluated magnetic resonance imaging and computed tomography images of vascular lesions located in the head and neck. Twelve patients (seven males, five females) aged 1-68 years (mean age, 35. Read More

Eur Arch Otorhinolaryngol 2015 Aug 12;272(8):1991-9. Epub 2014 Jun 12.

Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland.

Paragangliomas (PGs) are slowly growing, usually benign neoplasms. The aim of the study was to analyze the incidence, diagnostic and therapeutic management of patients with multiple paragangliomas of the head and neck. A retrospective review of the records of 84 patients with head and neck PGs, diagnosed and treated in our institution was performed for the years 1983-2013 to identify patients with multiple tumors. Read More

Clin Imaging 2014 Nov-Dec;38(6):815-20. Epub 2014 May 6.

The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, Baltimore, MD, USA. Electronic address:

Purpose: To assess the rate of jugular vein (JV) invasion by paragangliomas and imaging's ability to predict invasion.

Methods: Imaging studies of patients with paragangliomas were evaluated for JV invasion. Rates of invasion by different paragangliomas and each modality's accuracy were determined. Read More

Ear Nose Throat J 2013 Sep;92(9):430-4

Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, MMC 396, 420 Delaware Ave., SE, Minneapolis, MN 55455, USA.

We report the unique finding of a petrous apex cholesterol granuloma associated with a paraganglioma, also known as a glomus jugulare tumor, in a 52-year-old woman who presented to our department with pulsatile tinnitus, hearing loss, aural fullness, and disequilibrium. She had been treated for a petrous apex cholesterol granuloma 20 years earlier, at which time she had undergone drainage of the granuloma via subtotal petrous apicectomy. When she came to our facility approximately 20 years later, she had signs and symptoms consistent with a jugular paraganglioma, which was likely to have been present at the time of her initial presentation for the cholesterol granuloma. Read More

Head Neck 2014 Nov 18;36(11):1581-8. Epub 2013 Nov 18.

Gruppo Otologico Piacenza-Rome and University of Chieti, Italy.

Background: The classic infratemporal fossa type A approach (IFTA-A) permits superior and anterior exposure of the jugular foramen. The transcondylar-transtubercular extension facilitates posteroinferior and medial access to the jugular foramen. The purpose of this study was to present the IFTA-A with transcondylar-transtubercular extension and to assess its surgical results. Read More

J Neuropathol Exp Neurol 2013 Jul;72(7):600-13

Department of Pathology, The University of Colorado Health Sciences Center, Aurora, Colorado, USA.

Skull and dura serve as effective barriers to penetration by most tumors, often preventing masses originating intracranially from extending into the contiguous bone and soft tissues, or those arising in head and neck regions from extending into the dura and brain tissue. We review our 15-year experience with extracranial tumors that had sufficiently invaded adjacent skull, dura, or brain from the "outside-in" to require a neurosurgeon to participate in the surgical resection and discuss our 40 cases in context with the literature. Sinonasal-origin tumors (n = 17) and cutaneous tumors (n = 10) were the most frequent skull-invaders. Read More

J Nucl Med 2013 Jun 21;54(6):841-7. Epub 2013 Mar 21.

Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

Unlabelled: The purpose of this study was to evaluate the role of (68)Ga-labeled DOTANOC PET/CT for baseline evaluation of patients with head and neck paragangliomas (HNPs).

Methods: The data for 26 patients (mean age ± SD, 34.3 ± 10. Read More

Ear Nose Throat J 2012 Aug;91(8):366-75

ENT Department, Pugliese-Ciaccio Hospital, Catanzaro, Italy.

We conducted a retrospective study of the long-term functional results of surgery for head and neck paragangliomas. Our study population was made up of 9 patients--4 men and 5 women, aged 22 to 59 years (mean: 46.6; median: 51)--who had undergone surgical excision of a head and neck paraganglioma from January 2002 through December 2006 in the ENT Department at Pugliese-Ciaccio Hospital in Catanzaro, Italy. Read More