823 results match your criteria Imaging in Twin-to-Twin Transfusion Syndrome


Reversible parenchymal ischemic injury on fetal brain MRI following fetoscopic laser coagulation-Implication on parental counseling.

Radiol Case Rep 2020 Aug 27;15(8):1369-1372. Epub 2020 Jun 27.

Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

We present a case of reversible extensive ischemic injury seen on fetal-brain MRI in a fetus following laser coagulation performed for treatment of severe twin-twin transfusion syndrome twin-twin transfusion syndrome. A 32-year-old pregnant mother presented with twin-twin transfusion syndrome. Following fetoscopic laser coagulation, intrauterine fetal death of the donor fetus was diagnosed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radcr.2020.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327126PMC

Non-invasive dynamic observation of placental vascular anastomoses in monochorionic twins: Assessment using three-dimensional sonography combined with tomographic ultrasound imaging.

Placenta 2020 Jun 4;95:84-90. Epub 2020 May 4.

Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China. Electronic address:

Introduction: Three-dimensional (3D) sonography combined with tomographic ultrasound imaging (TUI) to observe placental vascular anastomoses in monochorionic diamniotic (MCDA) twin pregnancies was evaluated.

Methods: Women with MCDA twin pregnancies at a gestational age of 16-32 weeks were enrolled in this retrospective study. Placental anastomoses were detected using two-dimensional (2D) and 3D sonography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.placenta.2020.04.015DOI Listing

Neurodevelopmental impairment at 3 years of age after fetoscopic laser surgery for twin-to-twin transfusion syndrome.

Prenat Diagn 2020 Jul 13;40(8):1013-1019. Epub 2020 May 13.

Division of Fetal Medicine, Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.

Background: Data on neurodevelopmental outcomes of children surviving after fetoscopic laser surgery (FLS) for twin-to-twin transfusion syndrome (TTTS) are scarce.

Methods: We retrospectively investigated children surviving after FLS for TTTS at 16 to 26 weeks' gestation between 2003 and 2014. Children were evaluated by standardized neurologic examinations using the Kyoto Scale 2001 at a corrected age of 3 years ± 6 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pd.5726DOI Listing

Magnetic resonance imaging of the fetal brain in monochorionic diamniotic twin gestation: correlation of cerebral injury with ultrasound staging and survival outcomes.

Pediatr Radiol 2020 Jul 2;50(8):1131-1138. Epub 2020 May 2.

Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA.

Background: The current staging system of twin-twin transfusion syndrome (TTTS) is based on the ultrasound criteria and does not consider the cerebral injury.

Objective: To assess the incidence of cerebral damage on fetal MRI and correlate abnormal cerebral diffusion-weighted imaging (DWI) findings with survival outcome and the ultrasound staging of TTTS.

Materials And Methods: We conducted a retrospective review of MRI/DWI of fetal brains and the electronic medical records in monochorionic diamniotic twin gestations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00247-020-04661-wDOI Listing

Deep learning-based monocular placental pose estimation: towards collaborative robotics in fetoscopy.

Int J Comput Assist Radiol Surg 2020 Apr 30. Epub 2020 Apr 30.

Department of Mechanical Engineering, KU Leuven, Leuven, Belgium.

Purpose: Twin-to-twin transfusion syndrome (TTTS) is a placental defect occurring in monochorionic twin pregnancies. It is associated with high risks of fetal loss and perinatal death. Fetoscopic elective laser ablation (ELA) of placental anastomoses has been established as the most effective therapy for TTTS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11548-020-02166-3DOI Listing

FetNet: a recurrent convolutional network for occlusion identification in fetoscopic videos.

Int J Comput Assist Radiol Surg 2020 May 29;15(5):791-801. Epub 2020 Apr 29.

Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) and Department of Computer Science, University College London, London, UK.

Purpose: Fetoscopic laser photocoagulation is a minimally invasive surgery for the treatment of twin-to-twin transfusion syndrome (TTTS). By using a lens/fibre-optic scope, inserted into the amniotic cavity, the abnormal placental vascular anastomoses are identified and ablated to regulate blood flow to both fetuses. Limited field-of-view, occlusions due to fetus presence and low visibility make it difficult to identify all vascular anastomoses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11548-020-02169-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261278PMC

Deep Q-CapsNet Reinforcement Learning Framework for Intrauterine Cavity Segmentation in TTTS Fetal Surgery Planning.

IEEE Trans Med Imaging 2020 Apr 14. Epub 2020 Apr 14.

Fetoscopic laser photocoagulation is the most effective treatment for Twin-to-Twin Transfusion Syndrome, a condition affecting twin pregnancies in which there is a deregulation of blood circulation through the placenta, that can be fatal to both babies. For the purposes of surgical planning, we design the first automatic approach to detect and segment the intrauterine cavity from axial, sagittal and coronal MRI stacks. Our methodology relies on the ability of capsule networks to successfully capture the part-whole interdependency of objects in the scene, particularly for unique class instances (i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TMI.2020.2987981DOI Listing

Fetal therapies as standard prenatal care in Japan.

Obstet Gynecol Sci 2020 Mar 18;63(2):108-116. Epub 2020 Feb 18.

Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.

With recent advances in fetal medicine, various attempts have been made to save fetuses facing perinatal death or devastating consequences despite optimal management after birth. The concept of the fetus as a patient has been established through the application of treatments. This paper reviews fetal therapies in order to highlight the role of perinatal medicine as standard prenatal care. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5468/ogs.2020.63.2.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073354PMC

Twin Anemia Polycythemia Sequence.

N Engl J Med 2020 Feb;382(6):e9

Unidade Local de Saude do Alto Minho, Viana do Castelo, Portugal

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMicm1905895DOI Listing
February 2020

The body's integrated repair kit: Studying mesenchymal stem cells for better ligament repair.

Biomed J 2019 12;42(6):365-370

University of Copenhagen, BRIC Biotech Research & Innovation Centre, Anders Lund Group, Copenhagen, Denmark. Electronic address:

In this issue of the Biomedical Journal, we learn that the sport injury-prone knee ligaments might harbour their own repair kit in the form of mesenchymal stem cells, and that TERT transformation helps to keep these cells longer in culture for more extensive studies. In addition, we get a demonstration that diffusion tensor imaging can reliably show the activity of specific neural circuits, that rheumatoid arthritis patients are more prone to insulin resistance, and that platelet-enriched plasma gels significantly improve wound healing after pilonidal sinus surgery. Furthermore, two procreation-related articles inform us that growth hormone treatment improves endometrial receptivity in older women, and that elevated maternal liver enzymes do not impact on the outcome of laser therapy for twin-twin transfusion syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bj.2019.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962754PMC
December 2019

Early postnatal cardiac manifestations are associated with perinatal brain injury in preterm infants with twin to twin transfusion syndrome.

Sci Rep 2019 12 6;9(1):18505. Epub 2019 Dec 6.

Seoul National University College of Medicine, Department of Pediatrics, Seoul, 110-769, Republic of Korea.

Altered hemodynamics associated with twin to twin transfusion syndrome (TTTS) can be manifested in the fetal and neonatal heart. This study evaluated the association between cardiac manifestations immediately after birth and brain injury in preterm infants with TTTS. Medical records of preterm infants who were born at <35 weeks of gestation with TTTS and admitted to the neonatal intensive care unit at Seoul National University Children's Hospital between January 2011 and January 2018 were reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-54951-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898644PMC
December 2019

US Evaluation of Twin Pregnancies: Importance of Chorionicity and Amnionicity.

Radiographics 2019 Nov-Dec;39(7):2146-2166

From the Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628 (P.J., T.A.M.); and Department of Radiology and Imaging Sciences, University of Utah Medical Center, Salt Lake City, Utah (A.K.).

The twin birth rate is increasing in the United States. Twin pregnancies can be dichorionic or monochorionic (MC). MC twins account for 20% of twin pregnancies but 30% of all-cause pregnancy-related complications. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/rg.2019190042DOI Listing
November 2019
1 Read

Dichorionic pregnancy complicated by a twin-to-twin transfusion syndrome.

BMJ Case Rep 2019 Oct 30;12(10). Epub 2019 Oct 30.

Pathology, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Portugal.

Twin-to-twin transfusion syndrome (TTTS) is a serious complication typical of monochorionic pregnancies. Cases in dichorionic pregnancies have been described. The authors present a case report of a presumed TTTS in a dichorionic pregnancy followed at our institution in which the patient presented to the emergency department at 31 4/7 weeks' gestation complaining of lack of fetal movements. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2019-231614DOI Listing
October 2019

Photoacoustic imaging of the human placental vasculature.

J Biophotonics 2020 Apr 25;13(4):e201900167. Epub 2019 Nov 25.

Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.

Minimally invasive fetal interventions require accurate imaging from inside the uterine cavity. Twin-to-twin transfusion syndrome (TTTS), a condition considered in this study, occurs from abnormal vascular anastomoses in the placenta that allow blood to flow unevenly between the fetuses. Currently, TTTS is treated fetoscopically by identifying the anastomosing vessels, and then performing laser photocoagulation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbio.201900167DOI Listing

Prevalence of right ventricular outflow tract abnormalities among recipients in twin-twin transfusion syndrome after fetoscopic laser surgery in 90 consecutive cases.

J Med Ultrason (2001) 2020 Jan 22;47(1):117-121. Epub 2019 Oct 22.

Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube City, Yamaguchi, 755-8505, Japan.

Purpose: Right ventricular outflow tract obstruction (RVOTO) is a severe complication in recipients in twin-twin transfusion syndrome (TTTS). This study investigated the prevalence of RVOTO in TTTS after laser surgery and examined the risk factors for RVOTO.

Methods: This retrospective study evaluated 90 patients who had undergone laser surgery and been followed for 6 months after birth. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10396-019-00982-yDOI Listing
January 2020
1 Read

Asymmetrical Hemodynamic Influence of Twin-Twin Transfusion Syndrome on Fetal E/e' by the Dual Gate Doppler Method in Recipient Twins.

Fetal Diagn Ther 2020 1;47(4):261-267. Epub 2019 Oct 1.

Department of Obstetrics and Gynecology, Toho University Graduate School of Medicine, Tokyo, Japan.

Objectives: To assess the hemodynamic influence of twin-twin transfusion syndrome (TTTS) on diastolic function, using left ventricle (LV) and right ventricle (RV) E/e' measured in the same cardiac cycle using the dual-gate Doppler (DD) method.

Methods: This study included 56 monochorionic twin pregnancies that underwent fetoscopic laser surgery (FLS) for TTTS in 2015-2018. E/e' by the DD method was measured 24 h before and 4-7 days after FLS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000501773DOI Listing
October 2019
1 Read

Fetal and Neonatal Circulatory Disorders in Twin to Twin Transfusion Syndrome (The Secondary Publication).

Authors:
Hitoshi Yoda

J Nippon Med Sch 2019 ;86(4):192-200

Department of Neonatology, Toho University, Faculty of Medicine.

Twin to twin transfusion syndrome (TTTS) is a major complication of monochorionic diamniotic (MD) twins, and its onset is known to be associated with placental vascular anastomoses and blood flow imbalance. In a typical case of TTTS, the recipient develops polyhydramnios, weight gain, cardiomegaly and hydrops fetalis in the uterus. In contrast, the donor develops oligohydramnios and intrauterine growth restriction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1272/jnms.JNMS.2019_86-301DOI Listing
February 2020
2 Reads

The assessment of placental sharing using X-ray angiogram versus digital photograph: A prospective study.

Placenta 2019 08 7;83:1-4. Epub 2019 Jun 7.

Department of Obstetrics and Gynaecology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium; Department of Development and Regeneration, KULeuven, Herestraat 49, 3000, Leuven, Belgium. Electronic address:

Introduction: We aim to compare two different methods for the assessment of placental sharing in monochorionic diamniotic twins: X-ray-angiogram and digital photograph of the placenta.

Method: We included the placentas of a prospective series of twins that were followed from the first trimester onward and resulted in a double live birth or double stillbirth between April 2016 and February 2019. Injection was performed after delivery and an X-ray angiogram was made, as well as a digital photograph. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.placenta.2019.06.002DOI Listing
August 2019
1 Read

Multicystic encephalomalacia and gastrointestinal injury following single fetal death in first trimester and subsequent fetofetal transfusion syndrome in a monochorionic triplet pregnancy: a case report.

BMC Pregnancy Childbirth 2019 Aug 27;19(1):311. Epub 2019 Aug 27.

Department of Obstetrics and Gynecology, Tuen Mun Hospital, 23 Tsing Chung Koon Road, Tuen Mun, Hong Kong, Special Administrative Region of China.

Background: Monochorionic multifetal pregnancies are at increased risk of adverse perinatal outcome because of placental vascular anastomoses. We present a case of multicystic encephalomalacia and gastrointestinal injury in two surviving fetuses following single fetal death in first trimester and subsequent fetofetal transfusion syndrome in a monochorionic triplet pregnancy.

Case Presentation: A 31-year-old nulliparous woman had a spontaneous monochorionic triamniotic triplet pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12884-019-2459-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712839PMC
August 2019
3 Reads

Discrepancy in Doppler waveforms between two umbilical arteries in fetuses with absent or reversed end-diastolic flow: A prospective observational study.

J Clin Ultrasound 2019 Nov 24;47(9):526-530. Epub 2019 Aug 24.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Purpose: To asses the occurrence of discrepancies between the Doppler waveforms of the left and right umbilical arteries in their paravesical part in fetuses with absent or reversed end-diastolic flow in the free-floating umbilical cord.

Methods: This prospective observational study included pregnant women with fetal growth restriction or twin-to-twin transfusion syndrome. Umbilical arterial Doppler waveforms were obtained from both umbilical arteries in their intra-abdominal paravesical part. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcu.22770DOI Listing
November 2019
2 Reads

TTTS-GPS: Patient-specific preoperative planning and simulation platform for twin-to-twin transfusion syndrome fetal surgery.

Comput Methods Programs Biomed 2019 Oct 24;179:104993. Epub 2019 Jul 24.

BCN MedTech, Dept. of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain; ICREA, Barcelona, Spain.

Twin-to-twin transfusion syndrome (TTTS) is a serious condition that may occur in pregnancies when two or more fetuses share the same placenta. It is characterized by abnormal vascular connections in the placenta that cause blood to flow unevenly between the babies. If left untreated, perinatal mortality occurs in 90% of cases, whilst neurological injuries are still present in TTTS survivors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmpb.2019.104993DOI Listing
October 2019
1 Read

Pruning strategies for efficient online globally consistent mosaicking in fetoscopy.

J Med Imaging (Bellingham) 2019 Jul 7;6(3):035001. Epub 2019 Aug 7.

King's College London, School of Biomedical Engineering and Imaging Sciences, London, United Kingdom.

Twin-to-twin transfusion syndrome is a condition in which identical twins share a certain pattern of vascular connections in the placenta. This leads to an imbalance in the blood flow that, if not treated, may result in a fatal outcome for both twins. To treat this condition, a surgeon explores the placenta with a fetoscope to find and photocoagulate all intertwin vascular connections. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1117/1.JMI.6.3.035001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684965PMC
July 2019
4 Reads

The utility of MRI for measuring hematocrit in fetal anemia.

Am J Obstet Gynecol 2020 01 12;222(1):81.e1-81.e13. Epub 2019 Jul 12.

University of Toronto, Divisions of Cardiology, Toronto, Ontario, Canada. Electronic address:

Background: Doppler ultrasound measurements of the peak systolic velocity of the middle cerebral artery can be used to noninvasively diagnose fetal anemia but are less precise following fetal blood transfusion and in late gestation. We have previously demonstrated the feasibility of estimating fetal hematocrit in vitro using magnetic resonance imaging relaxation times. Here we report the use of magnetic resonance imaging as a noninvasive tool to accurately detect fetal anemia in vivo. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2019.07.016DOI Listing
January 2020
1 Read

The roles of superficial anastomoses in twin-twin transfusion syndrome.

Placenta 2019 07 9;82:5-9. Epub 2019 May 9.

Division of Obstetrics and Perinatology, Maternal and Perinatal Care Center, Seirei Hamamatsu General Hospital, Japan.

Objective: We aimed to evaluate whether types of vascular anastomoses affect fetal demise (FD) in twin-twin transfusion syndrome (TTTS) after fetoscopic laser photocoagulation (FLP).

Methods: All TTTS patients who underwent FLP in our institution from 2005 to 2017 were included. We described vascular anastomoses during FLP as either arterio-arterial (AA), veno-venous (VV), or arterial-venous (AV), and abnormal fetal Doppler waveforms before FLP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.placenta.2019.05.003DOI Listing
July 2019
16 Reads

Live born recipient of twin-twin transfusion syndrome with anomalous mitral arcade.

BMJ Case Rep 2019 May 29;12(5). Epub 2019 May 29.

Department of Pediatrics, St. Olavs University Hospital, Trondheim, Norway.

We present a case report of anomalous mitral arcade in a live born former recipient of twin-twin transfusion syndrome. At 33+0 week of gestation fetal ultrasound demonstrated that she had a large mitral insufficiency, decreased movement of the lateral cusp of the mitral valve and dilated left atrium. The twins were delivered by caesarean section at week 33+1 due to fetal distress. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2019-229237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557421PMC
May 2019
22 Reads

Real-time computerized video enhancement for minimally invasive fetoscopic surgery.

Laparosc Endosc Robot Surg 2018 Sep 22;1(2):27-32. Epub 2018 Jun 22.

Department of Radiology and Biomedical Imaging, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.

Background: The only definitive treatment for twin-to-twin transfusion syndrome is minimally invasive fetoscopic surgery for the selective coagulation of placental blood vessels. Fetoscopic surgery is a technically challenging operation, mainly due to the poor visibility conditions in the uterine environment. We present the design of an algorithm for the computerized enhancement of fetoscopic video and show that the enhanced video increases the ability of human users to identify blood vessels within fetoscopic video rapidly and accurately. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S24689009183000
Publisher Site
http://dx.doi.org/10.1016/j.lers.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508886PMC
September 2018
9 Reads

Successful use of fetoscopic laser surgery as treatment for a monochorionic-triamniotic triplet pregnancy complicated by twin-reversed arterial perfusion sequence and severe selective fetal growth restriction: A case report.

J Obstet Gynaecol Res 2019 Aug 7;45(8):1584-1587. Epub 2019 May 7.

Department of Obstetrics and Gynecology, Toho University Graduate School of Medicine, Tokyo, Japan.

Monochorionic triplet pregnancy is a rare condition, and twin-reversed arterial perfusion (TRAP) sequence and severe selective fetal growth restriction (FGR) are associated with high perinatal morbidity and mortality rates. We report a case of TRAP sequence and selective FGR typeIIconcurrently complicating a monochorionic triplet pregnancy. Fetoscopic laser surgery (FLS) was performed at 16 + 1 weeks of gestation and was technically successful. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.13994DOI Listing
August 2019
4 Reads

Assessment of cardiac function in donor and recipient fetuses during a 7-day follow-up after selective laser photocoagulation of communicating vessels due to TTTS.

Ginekol Pol 2019 ;90(4):189-194

Medical University of Gdansk, Department of Obstetrics, Gdansk, Poland.

Objectives: The aim of the study was to analyze the changes in cardiac function and myocardial contractility of donor and recipient fetuses with twin-to-twin transfusion syndrome (TTTS) subjected to selective laser photocoagulation of the communicating vessels (SLPCV), between and after the procedure. Finally, we verified if fetuses with Quintero's stage I TTTS presented with early impairment of myocardial contractility.

Material And Methods: We selected 77 consecutive women with twin pregnancies, whose both fetuses survived at least seven days post-SLPCV. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5603/GP.2019.0034DOI Listing
February 2020
9 Reads

Maternal and fetal cardiometabolic recovery following ultrasound-guided high-intensity focused ultrasound placental vascular occlusion.

J R Soc Interface 2019 05;16(154):20190013

2 Institute of Reproductive and Developmental Biology, Imperial College London , London W12 0HS , UK.

High-intensity focused ultrasound (HIFU) is a non-invasive method of selective placental vascular occlusion, providing a potential therapy for conditions such as twin-twin transfusion syndrome. In order to translate this technique into human studies, evidence of prolonged fetal recovery and maintenance of a healthy fetal physiology following exposure to HIFU is essential. At 116 ± 2 days gestation, 12 pregnant ewes were assigned to control ( n = 6) or HIFU vascular occlusion ( n = 6) groups and anaesthetized. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1098/rsif.2019.0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544891PMC
May 2019
7 Reads

Discordance of umbilical coiling index between recipients and donors in twin-twin transfusion syndrome.

Placenta 2019 01 18;76:19-22. Epub 2019 Jan 18.

Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Introduction: To compare the intertwin umbilical cord coiling in twin-twin transfusion syndrome (TTTS) before fetoscopic laser treatment and to correlate these with Doppler findings in both twins.

Methods: We performed a prospective study using three-dimensional (3D) ultrasound with color Doppler imaging of the umbilical cord in TTTS. Coiling index was measured as a reciprocal value of one complete vascular coil. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.placenta.2019.01.013DOI Listing
January 2019
10 Reads

Effect of intra-amniotic fluid pressure from polyhydramnios on cervical length in patients with twin-twin transfusion syndrome undergoing fetoscopic laser surgery.

Ultrasound Obstet Gynecol 2019 Dec;54(6):774-779

The Texas Fetal Center, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Medical School, Houston, TX, USA.

Objectives: To determine the relationship between intra-amniotic pressure and cervical length (CL) in patients with twin-twin transfusion syndrome (TTTS) undergoing fetoscopic laser photocoagulation (FLP), and to identify pre- or intraoperative factors associated with increased intra-amniotic pressure in this population.

Methods: This was a prospective cohort study of patients undergoing FLP for TTTS. Exclusion criteria were triplet or higher-order gestation and prior cervical cerclage, amnioreduction or FLP procedure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.20228DOI Listing
December 2019
14 Reads

An ultrasonographic estimated fetal weight reference for Japanese twin pregnancies.

J Med Ultrason (2001) 2019 Apr 27;46(2):209-215. Epub 2018 Dec 27.

Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.

Purpose: The purpose was to establish an estimated fetal weight (EFW) reference for twin pregnancies in Japan and to compare the growth of twins with singletons.

Methods: We retrospectively investigated Japanese women who delivered live-born twins at our center during the period from 2010 to 2016. The main exclusion criteria were monoamniotic twins, fetal reduction, maternal complications, twin-twin transfusion syndrome, fetal congenital anomalies, and patients with their first visit after 16 weeks' gestation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10396-018-0921-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438934PMC
April 2019
10 Reads

Bronchopulmonary Sequestration with Fetal Hydrops in a Monochorionic Twin Successfully Treated with Multiple Courses of Betamethasone.

AJP Rep 2018 Oct 3;8(4):e359-e361. Epub 2018 Dec 3.

Department of Gynaecology and Obstetrics, Third Faculty of Medicine, Charles University, Prague, Czech Republic.

 We present a case of severe bronchopulmonary sequestration (BPS) and fetal hydrops in one of the monochorionic twin successfully treated with multiple courses of betamethasone.  A 21-year-old gravida 2 para 1 was referred to our hospital for suspected twin-to-twin transfusion syndrome (TTTS) at 28 weeks of gestational age. However, prenatal ultrasound of the larger twin revealed a chest lesion that was associated with significant ascites, massive hydrothorax, scant hepatomegaly, subcutaneous edema, and severe polyhydramnios. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0038-1676339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277237PMC
October 2018
14 Reads

Isolated Ascites in a Monochorionic Twin after Fetoscopic Laser Ablation Is Not Necessarily Secondary to Recurrence or Anaemia: Bowel Complications in Twin-to-Twin Transfusion Syndrome after Fetoscopic Laser Ablation.

Fetal Diagn Ther 2019 14;45(5):285-294. Epub 2018 Dec 14.

Fetal Medicine Centre, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, United Kingdom.

Background/purpose: We report a case study of jejunal atresia and the results of a systematic literature review of all reported cases of bowel complications occurring after fetoscopic laser ablation (FLA) for the treatment of twin-to-twin transfusion syndrome (TTTS).

Methods: A systematic literature review was performed of bowel complications after FLA for TTTS according to PRISMA guidelines.

Results: There are 11 published cases of small bowel atresia, 5 cases of necrotising enterocolitis (NEC), and 2 cases with foetal bowel perforations. Read More

View Article

Download full-text PDF

Source
https://www.karger.com/Article/FullText/494616
Publisher Site
http://dx.doi.org/10.1159/000494616DOI Listing
December 2019
32 Reads

Twin-twin transfusion syndrome in dichorionic twin pregnancy: rare but not impossible.

Ultrasound Obstet Gynecol 2019 09 31;54(3):417-418. Epub 2019 Jul 31.

Fetal therapy Unit "U. Nicolini", Vittore Buzzi Children's Hospital, Università di Milano, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.20195DOI Listing
September 2019
5 Reads

A Comparison of Spinal Anesthesia Versus Monitored Anesthesia Care With Local Anesthesia in Minimally Invasive Fetal Surgery.

Anesth Analg 2020 02;130(2):409-415

Department of Anesthesiology, University of Utah, Salt Lake City, Utah.

Background: Minimally invasive fetal surgery is commonly performed to treat twin-to-twin transfusion syndrome with selective fetoscopic laser photocoagulation and twin-reversed arterial perfusion sequence using radiofrequency ablation. Although an increasing number of centers worldwide are performing these procedures, anesthetic management varies. Both neuraxial anesthesia and monitored anesthesia care with local anesthesia are used at different institutions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0000000000003947DOI Listing
February 2020
7 Reads

Deep-learned placental vessel segmentation for intraoperative video enhancement in fetoscopic surgery.

Int J Comput Assist Radiol Surg 2019 Feb 27;14(2):227-235. Epub 2018 Nov 27.

Yale University School of Medicine, New Haven, USA.

Introduction: Twin-to-twin transfusion syndrome (TTTS) is a potentially lethal condition that affects pregnancies in which twins share a single placenta. The definitive treatment for TTTS is fetoscopic laser photocoagulation, a procedure in which placental blood vessels are selectively cauterized. Challenges in this procedure include difficulty in quickly identifying placental blood vessels due to the many artifacts in the endoscopic video that the surgeon uses for navigation. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11548-018-1886-4
Publisher Site
http://dx.doi.org/10.1007/s11548-018-1886-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438174PMC
February 2019
11 Reads

Fetal stroke and cerebrovascular disease: Advances in understanding from lenticulostriate and venous imaging, alloimmune thrombocytopaenia and monochorionic twins.

Eur J Paediatr Neurol 2018 Nov 11;22(6):989-1005. Epub 2018 Sep 11.

Departments of Child Health, Obstetrics and Gynaecology and Radiology, University Hospital Southampton, United Kingdom; Clinical and Experimental Sciences, University of Southampton, United Kingdom.

Fetal stroke is an important cause of cerebral palsy but is difficult to diagnose unless imaging is undertaken in pregnancies at risk because of known maternal or fetal disorders. Fetal ultrasound or magnetic resonance imaging may show haemorrhage or ischaemic lesions including multicystic encephalomalacia and focal porencephaly. Serial imaging has shown the development of malformations including schizencephaly and polymicrogyra after ischaemic and haemorrhagic stroke. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejpn.2018.08.008DOI Listing
November 2018
42 Reads

Prognosis of the co-twin following spontaneous single intrauterine fetal death in twin pregnancies: a systematic review and meta-analysis.

BJOG 2019 Apr 26;126(5):569-578. Epub 2018 Nov 26.

Centre for Women's and Children Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.

Background: Single intrauterine fetal death affects approximately 6% of twin pregnancies and can have serious sequelae for the surviving co-twin.

Objectives: Determine the prognosis of the surviving co-twin following spontaneous single intrauterine fetal death to aid counselling patients and highlight future research areas.

Search Strategy: Medline, Embase, Web of Science, and Cochrane Library, from 1980 to June 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1471-0528.15530DOI Listing
April 2019
9 Reads

Segmentation and classification in MRI and US fetal imaging: Recent trends and future prospects.

Med Image Anal 2019 01 19;51:61-88. Epub 2018 Oct 19.

BCN MedTech, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain; ICREA, Barcelona, Spain.

Fetal imaging is a burgeoning topic. New advancements in both magnetic resonance imaging and (3D) ultrasound currently allow doctors to diagnose fetal structural abnormalities such as those involved in twin-to-twin transfusion syndrome, gestational diabetes mellitus, pulmonary sequestration and hypoplasia, congenital heart disease, diaphragmatic hernia, ventriculomegaly, etc. Considering the continued breakthroughs in utero image analysis and (3D) reconstruction models, it is now possible to gain more insight into the ongoing development of the fetus. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13618415183084
Publisher Site
http://dx.doi.org/10.1016/j.media.2018.10.003DOI Listing
January 2019
44 Reads

Acquired right ventricular outflow tract obstruction in twin-to-twin transfusion syndrome; a prospective longitudinal study.

Prenat Diagn 2018 12 28;38(13):1013-1019. Epub 2018 Nov 28.

Department of Obstetrics, Division of Fetal Medicine, Leiden University Medical Center, Leiden, Netherlands.

Objective: The pathophysiology of right ventricular outflow tract obstruction (RVOTO) in twin-to-twin transfusion syndrome (TTTS) recipients is incompletely understood. We aimed to investigate the development and spectrum of RVOTO in TTTS recipients.

Methods: A prospective longitudinal cohort study was conducted between 2015 and 2017. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/pd.5378
Publisher Site
http://dx.doi.org/10.1002/pd.5378DOI Listing
December 2018
14 Reads

Measurement of cardiac function by cardiac time intervals, applicability in normal pregnancy and twin-to-twin transfusion syndrome.

J Echocardiogr 2019 09 20;17(3):129-137. Epub 2018 Oct 20.

Division of Fetal Medicine, Department of Obstetrics, Leiden University Medical Center, B3-089, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

Background: To detect early cardiac deterioration, a simple and stable tool is needed. Measurement of time intervals in a simple 4-chamber view using color-coded tissue Doppler imaging is a relatively new approach to assess fetal cardiac function. The aim of this study was to evaluate the applicability of this modality and to construct reference ranges for cardiac time intervals. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12574-018-0401-9
Publisher Site
http://dx.doi.org/10.1007/s12574-018-0401-9DOI Listing
September 2019
12 Reads

The incidence of unexpected critical complications in monochorionic diamniotic twin pregnancies according to the interval period between ultrasonographic evaluations.

J Obstet Gynaecol Res 2019 Feb 10;45(2):318-324. Epub 2018 Oct 10.

Department of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, Japan.

Aim: This study aimed to evaluate the incidence of unexpected critical complications (UCC) in monochorionic diamniotic (MCDA) twin pregnancies according to ultrasonographic scan interval.

Methods: This retrospective single-center cohort study, conducted between January 2005 and April 2015, investigated the incidence of UCC in patients with MCDA twin pregnancies undergoing weekly ultrasound (Group A) and those undergoing biweekly ultrasound (Group B). We also examined the incidence of predictable critical complications according to ultrasound interval. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/jog.13827
Publisher Site
http://dx.doi.org/10.1111/jog.13827DOI Listing
February 2019
11 Reads

Bisphosphonate therapy in an infant with generalized arterial calcification with an ABCC6 mutation.

Osteoporos Int 2018 Nov 11;29(11):2575-2579. Epub 2018 Sep 11.

Center For Endocrinology, Diabetes and Metabolism, Children's Hospital Los Angeles and Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.

Generalized arterial calcification of infancy (GACI) is a rare genetic disorder with high infantile mortality, described to be due to ENPP1, and less commonly ABCC6 mutations. Bisphosphonate treatment has been described to improve survival in ENPP1-positive GACI patients, but few studies have described bisphosphonate treatment in ABCC6-positive patients. Without therapy, patients will die before 6 months of age. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00198-018-4639-xDOI Listing
November 2018
4 Reads

Twin Reversed Arterial Perfusion Sequence: Assessing the Role of the Correct Imaging Modality in a Rare Clinical Entity.

Cureus 2018 Jul 2;10(7):e2910. Epub 2018 Jul 2.

Department of Pathology, Aga Khan University Hospital, Karachi, PAK.

Acardiac twin formation is a rare anomaly. It is one of the most extreme complications of monozygotic twin pregnancies. Such occurrences are brought about when a normal twin donates blood to an abnormal twin through its umbilical arteries via vascular anastomoses at the level of the placenta, which is termed as twin reversed arterial perfusion sequence (TRAPS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.2910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122656PMC
July 2018
30 Reads

Monochorionic-diamniotic twin pregnancy complicated by twin reversed arterial perfusion sequence and retroplacental hematoma - a case report.

Med Ultrason 2018 Aug;20(3):396-398

2nd Obstetrics and Gynecology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Twin reversed arterial perfusion (TRAP) sequence is a rare and severe complication specific to monochorionic twin pregnancies, involving the presence of an acardiac twin and a structurally normal co-twin (pump twin). We report on the case of a33-year-old female with a biamniotic monochorionic twin pregnancy complicated with TRAP sequence and polyhydramnios. The patient underwent fetoscopic termination of the acardiac twin and at 34 gestational weeks (GW) was readmitted with aretroplacental hematoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11152/mu-1486DOI Listing
August 2018
8 Reads

Treatment of twin-reversed arterial perfusion sequence using high-intensity focused ultrasound.

Ultrasound Obstet Gynecol 2019 Jul;54(1):128-134

Showa University, School of Medicine, Department of Obstetrics and Gynecology, Tokyo, Japan.

We describe our experience of high-intensity focused ultrasound (HIFU) for fetal therapy in twin-reversed arterial perfusion (TRAP) sequence. Six pregnant women underwent HIFU therapy, five before 16 weeks and one at 26 weeks. Two types of HIFU system were used: the first-generation system, which comprised a biaxial transducer and continuous exposure pattern, and the second-generation system, which comprised a coaxial transducer and sequential exposure pattern. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.20101DOI Listing
July 2019
43 Reads

Improved prediction of twin anemia-polycythemia sequence by delta middle cerebral artery peak systolic velocity: new antenatal classification system.

Ultrasound Obstet Gynecol 2019 Jun 6;53(6):788-793. Epub 2019 May 6.

Division of Fetal Medicine, Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.

Objectives: To investigate the diagnostic accuracy of delta middle cerebral artery peak systolic velocity (MCA-PSV) > 0.5 multiples of the median (MoM) and compare its predictive value with that of the current MCA-PSV cut-off values of > 1.5 MoM in the donor and < 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.20096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593803PMC
June 2019
13 Reads

Variation in outcome reporting across studies evaluating interventions for selective fetal growth restriction.

Ultrasound Obstet Gynecol 2019 Jul;54(1):10-15

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.19192DOI Listing
July 2019
9 Reads

A mixed-reality surgical trainer with comprehensive sensing for fetal laser minimally invasive surgery.

Int J Comput Assist Radiol Surg 2018 Dec 27;13(12):1949-1957. Epub 2018 Jul 27.

Department of Mechanical Engineering, KU Leuven, Leuven, Belgium.

Purpose: Smaller incisions and reduced surgical trauma made minimally invasive surgery (MIS) grow in popularity even though long training is required to master the instrument manipulation constraints. While numerous training systems have been developed in the past, very few of them tackled fetal surgery and more specifically the treatment of twin-twin transfusion syndrome (TTTS). To address this lack of training resources, this paper presents a novel mixed-reality surgical trainer equipped with comprehensive sensing for TTTS procedures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11548-018-1822-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223750PMC
December 2018
30 Reads
1.660 Impact Factor