Search Our Scientific Publications & Authors

J Alzheimers Dis 2021 Jun 1. Epub 2021 Jun 1.

The Framingham Heart Study, Framingham, MA, USA.

Background: Adherence to the Mediterranean-DASH for Neurodegenerative Delay (MIND) diet has previously been associated with cognitive decline and dementia. To our knowledge, no prior study has investigated the association between the MIND diet and measures of brain volume, silent brain infarcts (SBIs), or brain atrophy.

Objective: We evaluated whether adherence to the MIND diet associated with superior cognitive function, larger brain volumes, fewer SBIs, and less cognitive decline in the community-based Framingham Heart Study. Read More

Clin Neurol Neurosurg 2021 May 29;207:106712. Epub 2021 May 29.

Department of Neurosurgery, University Hospital of Wales, Cardiff, UK. Electronic address:

Introduction: Surgical evacuation of acute subdural haematoma (ASDH) in the elderly remains a point of contention due to the significant associated mortality. Therefore, there is a dire need for alternative treatment options. Endoscope-assisted techniques (EAT) have been increasingly reported over the last decade with variable outcomes. Read More

J Clin Neurosci 2021 Jul 2;89:365-374. Epub 2021 Jun 2.

Department of Radiology, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, South Korea.

An understanding of the common MRI findings observed after decompression surgery is important. However, to date, no study addressing this has been published. The aim of this study was to analyze and describe the immediate postoperative MRI findings after lumbar decompression surgery. Read More

Exp Ther Med 2021 Jul 13;22(1):757. Epub 2021 May 13.

Department of Neurosurgery, Faculty of Medicine, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

In the present study, we aimed to assess and analyze the predictive factors of 30-day mortality in patients with acute subdural hematoma (ASDH) who underwent surgical intervention after traumatic brain injury (TBI). We conducted a retrospective study, which included a cohort of 135 consecutive patients diagnosed with ASDH who required surgical evacuation. We assessed the demographic and clinical data, the imaging data of the hematoma described by preoperative computed tomography (CT) and the type of neurosurgical intervention for hematoma evacuation via either craniectomy or craniotomy. Read More

Hum Genome Var 2021 May 24;8(1):20. Epub 2021 May 24.

Department of human genetics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.

We describe two patients with NSD1 deletion, who presented with early-onset, or recurrent cerebrovascular diseases (CVDs). A 39-year-old female showed developmental delay and abnormal gait in infancy, and developed slowly-progressive intellectual disability and movement disorders. Brain imaging suggested recurrent parenchymal hemorrhages. Read More

J Neurosurg 2021 May 21:1-9. Epub 2021 May 21.

Objective: Chronic subdural hematoma (cSDH) is a common and challenging pathology to treat due to both the historically high recurrence rate following surgical evacuation and the medical comorbidities inherent in the aging patient population that it primarily affects. Middle meningeal artery (MMA) embolization has shown promise in the treatment of cSDHs, most convincingly to avoid surgical evacuation in relatively asymptomatic patients. Symptomatic patients requiring surgical evacuation may also benefit from perioperative MMA embolization to prevent cSDH recurrence. Read More

Brain Inj 2021 May 16:1-5. Epub 2021 May 16.

Department of Neurosurgery, University of Florida College of Medicine, Gainesville, Florida, USA.

The purpose of this study was to determine the utility of CT imaging in patients with non-operative mild-moderate TBI with respect to changes in management. We conducted a retrospective analysis for 191 patients over a 5-year interval to examine whether follow-up CT initiated a change in management. We created a logistic regression model to incorporate different variables contributing to change in management. Read More

Korean J Neurotrauma 2021 Apr 18;17(1):61-66. Epub 2021 Mar 18.

Department of Rehabilitation Medicine, Kwangju Christian Hospital, Gwangju, Korea.

Ipsilateral hemiparesis is a rare and challenging sign in clinical neurological practice. Although the etiology of this manifestation is poorly understood, recent studies have attempted to probe the pathomechanism of this sign with advanced radiological techniques. Additional knowledge about the lesion and unraveling the pathomechanisms causing neurological impairments are important to predict the prognosis and clinical course and to aid in rehabilitation. Read More

Korean J Neurotrauma 2021 Apr 20;17(1):34-40. Epub 2021 Apr 20.

Department of Neurosurgery, VHS Medical Center, Seoul, Korea.

Objective: Subdural hematoma (SDH) primarily occurs in elderly patients. While most patients have good prognosis, some do not. Hematoma recurrence is one of the factors influencing prognosis. Read More

Acta Paediatr 2021 May 8. Epub 2021 May 8.

Department of Clinical Medicine K1, University of Bergen, Bergen, Norway.

Aim: Thrombosis of bridging veins has been suggested to be a marker of bridging vein rupture, and thus AHT, in infants with subdural haematoma.

Methods: This is a non-systematic review based on Pubmed search, secondary reference tracking and authors' own article collections.

Results: Radiological studies asserting that imaging signs of cortical vein thrombosis were indicative of traumatic bridging vein rupture were unreliable as they lacked pathological verification of either thrombosis or rupture, and paid little regard to medical conditions other than trauma. Read More

BMJ Case Rep 2021 May 7;14(5). Epub 2021 May 7.

Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK.

Both acute and chronic subdural haematomas typically occur following trauma. Non-traumatic causes are less common, but aetiologies include arteriovenous malformation, intracranial aneurysm rupture, tumour-associated haemorrhage and coagulopathies. May-Hegglin anomaly is an example of a coagulopathy, which is caused by a mutation in the gene encoding non-muscle myosin heavy chain 9 (MYH9) and therefore falls into a group of diseases referred to as MYH9-related diseases (MYH9-RD). Read More

Cureus 2021 Mar 31;13(3):e14212. Epub 2021 Mar 31.

Radiology, St Barnabas Hospital Health System, Bronx, USA.

Intracranial hemorrhage (ICH) as a unique image finding, is a rare presentation of glioblastoma (GBM), and can pose a diagnostic challenge. Hypertensive vascular changes are responsible for the majority of the ICH cases, where hemorrhage from brain tumors account only for 5.1% to 7. Read More

World Neurosurg 2021 May 1. Epub 2021 May 1.

Department of Neurosurgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania; Neurosciences Institute, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Background: Epidural hematoma causing brain herniation is a major cause of mortality and morbidity after severe traumatic brain injury, even if surgical treatment is performed quickly. Decompression may be effective in decreasing intracranial pressure, but its effect on outcomes remains unclear.

Methods: A retrospective analysis of deeply comatose patients (Glasgow Coma Scale score 3-5) who underwent surgical treatment during a 12-year period, either via osteoplastic craniotomy (OC) or decompressive craniectomy, was carried out. Read More

World Neurosurg 2021 Apr 30. Epub 2021 Apr 30.

Division of Neurosurgery, Southern Illinois University School of Medicine, Springfield, Illinois, USA.

Background: Neurosurgeons are frequently consulted for traumatic brain injuries (TBIs) resulting in intracranial hemorrhage (ICH). After inpatient confirmation of hemorrhage stability, outpatient head computed tomography (CT) is often performed to assess for hemorrhage resolution. Our objective was to assess the practice patterns and clinical utility of routine outpatient head CT scans for patients with mild TBI (mTBI). Read More

Radiol Case Rep 2021 Jun 13;16(6):1454-1458. Epub 2021 Apr 13.

Department of Radiology Orthopedic surgery, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.

Spinal subdural hematoma is a rare condition presenting with symptoms of back pain and neurologic deficits. The etiology is largely idiopathic, followed by anti-coagulant use and vascular malformation. Traumatic subdural hematomas associated with compression fractures are rare, with only a few old case reports. Read More

J Neurointerv Surg 2021 Apr 28. Epub 2021 Apr 28.

Neurosurgery, Wake Forest University, Winston-Salem, North Carolina, USA.

Background: Venous sinus stenting (VSS) is a safe, effective, and increasingly popular treatment option for selected patients with idiopathic intracranial hypertension (IIH). Serious complications associated with VSS are rarely reported.

Methods: Serious complications after VSS were identified retrospectively from multicenter databases. Read More

BMJ Case Rep 2021 Apr 26;14(4). Epub 2021 Apr 26.

Department of Neurosurgery, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, Arizona, USA

A man in his 50s presented 1 month after an automobile accident with worsening headaches and an enlarging chronic left subdural haematoma (SDH). He underwent left middle meningeal artery (MMA) embolisation. Due to tortuosity at its origin, we were unable to catheterise the MMA distally. Read More

BMC Surg 2021 Apr 27;21(1):219. Epub 2021 Apr 27.

Department of Emergency and Critical Care Medicine, Kansai Medical University Hospital, 2-3-1 Shinmachi, Hirakata, Osaka, 573-1191, Japan.

Background: A novel trauma workflow system called the hybrid emergency room (Hybrid ER), which combines a sliding CT scanner system with interventional radiology features (IVR-CT), was initially instituted in our emergency department in 2011. Use of the Hybrid ER enables CT diagnosis and emergency therapeutic interventions without transferring the patient to another room. We describe an illustrative case of severe multiple blunt trauma that included injuries to the brain and torso to highlight the ability to perform multiple procedures in the Hybrid ER. Read More

Radiol Technol 2021 May;92(5):459-466

Lecturer for the department of Medical Imaging and Therapeutic Sciences and is a faculty member of Health and Wellness Sciences for the Cape Peninsula University of Technology, South Africa.

Purpose: To assess the type and degree of neurological complications in patients with traumatic brain injury (TBI) who presented with an initial typical baseline computed tomography (CT) brain scan and to assess the time in which neurological complications developed.

Methods: A retrospective cross-sectional quantitative research design was conducted in whichCT radiology reports of 85 adult patients with TBI and typical baseline CT scans were analyzed during a 2-year period. The evolution of different types of neurological pathology diagnosed on follow-up CT brain imaging in these patients was recorded and analyzed. Read More

BMC Neurol 2021 Apr 27;21(1):178. Epub 2021 Apr 27.

Department of Neurosurgery, University of California San Diego, La Jolla, 1335 Sunset Cliffs Boulevard, San Diego, CA, 92107, USA.

Background: Top of the basilar syndrome is a rare, heterogeneous disorder that has previously only been described in the setting of acute ischemic stroke in predominantly elderly patients. We present the first reported case of traumatic brain injury (TBI) causing ischemia in a top of the basilar distribution.

Case Presentation: A 19-year-old woman suffered an acute subdural hematoma and sustained hypoxemia after being struck by a motor vehicle. Read More

BMC Anesthesiol 2021 Apr 26;21(1):130. Epub 2021 Apr 26.

Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Sichuan Province, Chengdu, China.

Background: Subdural anesthesia and spinal subdural hematoma are rare complications of combined spinal-epidural anesthesia. We present a patient who developed both after multiple attempts to achieve combined spinal-epidural anesthesia.

Case Presentation: A 21-year-old parturient, gravida 1, para 1, with twin pregnancy at gestational age 34 weeks underwent cesarean delivery. Read More

Pediatr Neurol 2021 06 9;119:48-49. Epub 2021 Mar 9.

Pediatric Neuroradiologist, Department of Radiology, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana. Electronic address:

J Neurol Sci 2021 06 19;425:117467. Epub 2021 Apr 19.

Anesthesiology and Intensive Care Department, AOR San Carlo, Potenza (IT), Italy.

Background: The occurrence of cerebral venous thrombosis (CVT) in patients with spontaneous intracranial hypotension (SIH) raises difficult practical questions regarding the management of the two conditions. The first-line therapy for CVT is anticoagulation (AC); however, its potential benefit in SIH/CVT patients, especially if complicated by subdural haematoma, must be carefully evaluated taking account of the intracranial haemorrhage risk. Venous system recanalization and good prognosis in SIH/CVT patients treated with epidural blood patch (EBP), the main treatment option for SIH, have been already described. Read More

Pan Afr Med J 2021 25;38:80. Epub 2021 Jan 25.

Department of Internal Medicine, Faculty of Clinical Sciences, College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.

Introduction: chronic subdural hematoma (cSDH) is not uncommon in sub-Saharan Africa and has a striking morbidity and mortality if not managed adequately. With the limited number of neurosurgeons in resource poor countries, general surgeons should be trained in the skills of craniotomy and burr-hole craniostomy.

Methods: we conducted a retrospective review of all medical records of patients with cSDH, who underwent flap craniotomy at the Choithrams Memorial Hospital, Sierra Leone, between January 2016 and March 2018. Read More

Pediatr Radiol 2021 May 21;51(6):918-926. Epub 2021 Apr 21.

Department of Radiology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Slot 556, Little Rock, AR, 72205, USA.

Abusive head trauma (AHT) is the leading cause of fatal head injuries in children younger than 2 years. An intracranial pathology can exist even in the setting of a normal physical exam. A delay in the diagnosis of AHT can have serious life-threatening consequences for the child and increases the potential the child will be abused again. Read More

Childs Nerv Syst 2021 Apr 14. Epub 2021 Apr 14.

School of Medicine& School of Clinical Medicine, Tsinghua University, Beijing, China.

Introduction: Dural sinus malformation is a rare congenital malformation characterized by a remarkable dilated dural sinus pouch. We described the development of bilateral subdural hematoma after endovascular embolization of a dural sinus malformation in an infant.

Case Description: A 32-day male infant was observed to have a fever and enlarged head circumference. Read More

Neuroradiol J 2021 Apr 12:19714009211009112. Epub 2021 Apr 12.

Department of Radiology, Neuroradiology and Nuclear Medicine, Ruhr-University Bochum, Germany.

Background: Data on outcome of endovascular treatment in patients with acute ischaemic stroke due to large vessel occlusion suffering from intravenous thrombolysis-associated intracranial haemorrhage prior to mechanical thrombectomy remain scarce. Addressing this subject, we report our multicentre experience.

Methods: A retrospective analysis of consecutive acute ischaemic stroke patients treated with mechanical thrombectomy due to large vessel occlusion despite the pre-interventional occurrence of intravenous thrombolysis-associated intracranial haemorrhage was performed at five tertiary care centres between January 2010-September 2020. Read More

Acta Neurochir Suppl 2021 ;131:51-54

Lovelace Biomedical Research Institute, Albuquerque, NM, USA.

Introduction: The knowledge of conservative treatment modalities for a chronic subdural hematoma (CSDH) is still based on low-grade evidence. The purpose of this study was to evaluate the condition of the microcirculation and autoregulation in the perifocal CSDH zone for understanding of the mechanism of CSDH development.

Methods: Cerebral microcirculation was evaluated in patients with the aid of brain perfusion computed tomography (PCT) within the first day. Read More

J Spine Surg 2021 Mar;7(1):118-123

Department of Neurosurgery, Chungdam Wooridul Spine Hospital, Seoul, South Korea.

The use of full-endoscopic decompression for lumbar spinal stenosis has been increasing recently. It is a minimally invasive surgical procedure that has few complications. Spinal subdural hematoma (SSH) following endoscopic surgery has never been reported. Read More

Pediatr Radiol 2021 May 8;51(6):939-946. Epub 2021 Apr 8.

Department of Radiology, University of Arkansas for Medical Sciences (UAMS), Little Rock, AR, USA.

Background: Birth trauma accounts for 1-2% of the mortality in newborns with significant intracranial injuries presenting in the immediate postnatal period. However, a significant number of asymptomatic neonates harbor birth-related intracranial hemorrhage (ICH), with birth-related subdural hemorrhage (SDH) being a common occurrence on infant brain CT and MRI studies performed as a standard of care for a variety of reasons. Although clinically insignificant, birth-related SDH is frequently brought up in courts as an alternative explanation for SDH in suspected abusive head trauma. Read More