135 results match your criteria Imaging in Spine Hemangioblastoma


Dumbbell-Shaped Extramedullary Hemangioblastoma of the Thoracic Spine as a Diagnostic Dilemma of Solitary Fibrous Tumor.

Int Med Case Rep J 2021 12;14:77-81. Epub 2021 Feb 12.

Department of Pathology, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala, Uganda.

Introduction: Extramedullary hemangioblastoma is a very rare entity that has been rarely reported in the literature.

Case Presentation: A 17-year-old female presented with limping that rapidly progressed to paraparesis and urine incontinence over a one-month duration. Clinically, she had a small swelling on her spine. Read More

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February 2021

Microsurgical Resection of an Intramedullary Spinal Cord Hemangioblastoma Through an Anterior Cervical Approach: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 01;20(2):E133

Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, New York.

This video demonstrates the microsurgical removal of an intramedullary spinal cord hemangioblastoma through an anterior cervical approach. While most spinal hemangioblastomas arise from the dorsal or dorsolateral pial surface and can be safely resected through a posterior approach,1,2 ventral tumors can present a significant challenge to safe surgical removal.3-5 This patient presented with a progressively symptomatic ventral pial based hemangioblastoma at the C5-6 level with large polar cysts extending from C3 to T1. Read More

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January 2021

Spinal hemangioblastoma arising from cervical nerve root.

Neurology 2020 10 15;95(17):791-792. Epub 2020 Sep 15.

From the Departments of Neurosurgery (J.L., J.H., X.H., H.C.) and Pathology (S.L.), West China Hospital of Sichuan University, Chengdu.

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October 2020

Von Hippel-Lindau Syndrome: Multi-Organ Involvement Highlighting Its Diverse Clinical Spectrum in Two Adult Cases.

Cureus 2020 Jul 26;12(7):e9402. Epub 2020 Jul 26.

Neurology, University of New Mexico School of Medicine, Albuquerque, USA.

There is an assortment of disorders that have multisystem involvement. Von Hippel-Lindau (VHL) syndrome, a rare autosomal dominant disease, falls in that category. VHL syndrome is associated with the formation of benign and malignant tumors in the central nervous system (CNS), adrenal gland, kidney, and eyes. Read More

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Cerebellar Hemangioblastoma: Diagnostic Yield of Contrast-Enhanced Abdominal CT and Whole-Spine MRI as Initial Screening Imaging.

AJR Am J Roentgenol 2020 09 22;215(3):706-712. Epub 2020 Jul 22.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Olympic-ro 33, Seoul, 05505, Republic of Korea.

The existing literature lacks research into the benefits of initial screening imaging for patients with cerebellar hemangioblastoma. We aimed to evaluate the diagnostic yield of initial screening imaging using abdominal CT and whole-spine MRI in patients with cerebellar hemangioblastoma. This retrospective study included 117 consecutive patients with histopathologically confirmed, newly diagnosed cerebellar hemangioblastomas at a single tertiary hospital between January 2006 and October 2018. Read More

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September 2020

Spinal paraganglioma as unusual finding in von Hippel-Lindau disease.

J Clin Neurosci 2020 Jul 7;77:217-221. Epub 2020 May 7.

Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

A 20-year-old patient with a history of von Hippel-Lindau disease reported on thoracic back pain radiating to the left shoulder for 10 weeks. Magnetic resonance imaging revealed a progressive contrast-enhancing tumor (14 × 21 × 28 mm) compressing the spinal cord and extending into the left neural foramen at T5/6. After embolization of supplying vessels, the tumor was completely resected via hemilaminectomy of T5. Read More

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Surgical Management of Intramedullary Spinal Cord Tumors.

Neurosurg Clin N Am 2020 Apr 31;31(2):237-249. Epub 2020 Jan 31.

Department of Neurological Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Department of Neurological Surgery, Weill Cornell Medical College, 525 E. 68th St, New York, NY 10065, USA.

Intramedullary spinal cord tumors (IMSCT) comprise a rare subset of CNS tumors that have distinct management strategies based on histopathology. These tumors often present challenges in regards to optimal timing for surgery, invasiveness, and recurrence. Advances in microsurgical techniques and technological adjuncts have improved extent of resection and outcomes with IMSCT. Read More

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Microsurgical treatment of cervical spinal hemangioblastoma.

Neurochirurgie 2020 Feb 14;66(1):56-60. Epub 2020 Jan 14.

Department of Neurosurgery, Wuxi Second Hospital Affiliated to Nanjing Medical University, 68 Zhongshan Road, Wuxi 214002, Jiangsu, China. Electronic address:

Background: Hemangioblastoma is a rare intracranial vascular tumor, mostly found in the cerebellum. Cervical spinal hemangioblastoma (CSHB) has rarely been reported, and microsurgical treatment even less.

Objective: To present our experience with CSHB and conduct a literature review, in order to provide a systematic approach to diagnosis and microsurgical treatment. Read More

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February 2020

Microsurgical Resection of Intraspinal Benign Tumors Using Non-Expansile Tubular Access.

World Neurosurg 2020 Jan 7;133:e97-e104. Epub 2019 Sep 7.

Spine Clinic, The American-British Cowdray Medical Center I.A.P. Campus Santa Fe, Mexico City, Mexico; National Autonomous University of Mexico, Mexico City, Mexico; Regional General Hospital #25 of the National Institute of Social Security, Mexico City, Mexico; Department of Neurology, Medicine School, University of Sonora, Obregon City, Mexico. Electronic address:

Background: Intraspinal tumors are 10 to 15 times less common than brain tumors. The midline approach with extensive laminectomies represents the current gold-standard for resection, causing instability, muscle damage, and kyphosis among other well-known complications. Minimally invasive series reported their results using retractor-based systems. Read More

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January 2020

Minimally invasive resection of spinal hemangioblastoma: feasibility and clinical results in a series of 18 patients.

J Neurosurg Spine 2019 Aug 9:1-10. Epub 2019 Aug 9.

1Department of Neurosurgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Objective: Hemangioblastomas are benign, highly vascularized tumors that can occur sporadically or as part of von Hippel-Lindau (VHL) disease. Traditionally, spinal hemangioblastomas have been surgically treated via an open approach. In recent years, however, minimally invasive techniques using tubular retractors have been increasingly applied in spine surgery. Read More

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Navigated 3-Dimensional Intraoperative Ultrasound for Spine Surgery.

World Neurosurg 2019 Nov 31;131:e155-e169. Epub 2019 Jul 31.

Department of Neurosurgery, University Marburg, Marburg, Germany.

Objective: To integrate 3-dimensional (3D) intraoperative ultrasound (iUS) data in spinal navigation.

Methods: In 11 patients with intradural spinal tumors, 3D-iUS was performed before and after tumor resection. Intraoperative computed tomography (iCT) was used for automatic patient registration for spinal navigation; fiducial-based registration was performed in 1 case. Read More

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November 2019

Augmented reality in intradural spinal tumor surgery.

Acta Neurochir (Wien) 2019 10 12;161(10):2181-2193. Epub 2019 Jul 12.

Department of Neurosurgery, University Marburg, Baldingerstrasse, 35033, Marburg, Germany.

Background: Microscope-based augmented reality (AR) is commonly used in cranial surgery; however, until recently, this technique was not implemented for spinal surgery. We prospectively investigated, how AR can be applied for intradural spinal tumor surgery.

Methods: For ten patients with intradural spinal tumors (ependymoma, glioma, hemangioblastoma, meningioma, and metastasis), AR was provided by head-up displays (HUDs) of operating microscopes. Read More

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October 2019

Use of Intraoperative Indocyanine Green Angiography for Feeder Vessel Ligation and En Bloc Resection of Intramedullary Hemangioblastoma.

Oper Neurosurg (Hagerstown) 2019 12;17(6):573-579

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background: As vascular tumors, intramedullary hemangioblastomas are associated with significant intraoperative blood loss, making them particularly challenging clinical entities. The use of intraoperative indocyanine green or other fluorescent dyes has previously been described to avoid breaching the tumor capsule, but improved surgical outcomes may result from identifying and ligating the feeder arteries and arterialized draining veins.

Objective: To describe the use of combined preoperative angiography and intraoperative indocyanine green use for the identification of feeder arteries and arterialized draining veins to decrease blood loss in the resection of intramedullary hemangioblastomas. Read More

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December 2019

Surgical management of a cervical intramedullary hemangioblastoma presenting with intracystic hemorrhage by hemi-semi-laminectomy via a posterior approach.

J Int Med Res 2019 Jul 30;47(7):3458-3464. Epub 2019 May 30.

1 Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

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68Ga DOTATATE PET/CT Versus 18F-FDG PET/CT for Detecting Intramedullary Hemangioblastoma in a Patient With Von Hippel-Lindau Disease.

Clin Nucl Med 2019 Jun;44(6):e385-e387

Nuclear Medicine & Molecular Imaging Department, Imam Reza International University, Mashhad, Iran.

Von Hippel-Lindau disease is an inherited syndrome associated with several benign and malignant tumors such as central nervous system (CNS) hemangioblastoma. Herein, we report a known case of A Von Hippel-Lindau patient with a cerebral hemangioblastoma who was referred for further evaluation because of recent paraparesis. F-FDG PET/CT showed no focal uptake in the thoracic spine, which demonstrated increased Ga DOTATATE activity, owing to overexpression of somatostatin receptors, suggesting spinal cord hemangioblastoma. Read More

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Cauda Equina Syndrome as First Manifestation of von Hippel-Lindau Disease.

World Neurosurg 2019 05 16;125:316-319. Epub 2019 Feb 16.

Department of Orthopedics, Zhejiang Provincial People's Hospital, Hangzhou, China; Hangzhou Medical College People's Hospital, Hangzhou, China. Electronic address:

Background: Von-Hippel Lindau (VHL) disease is rare neurocutaneous disorder arising from an inactivating mutation of the VHL gene on chromosome 3p35. The disease is inherited in an autosomal dominant fashion and predominantly involves tissues originating from the ectodermal germ layer. Although hemangioblastomas of retina and cerebellum are the most common clinical features, multiple-organ involvement in the form of renal cell carcinomas, spinal hemangioblastomas, renal cysts, and pancreatic cysts have also been reported. Read More

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Imaging of Vascular Disorders of the Spine.

Radiol Clin North Am 2019 Mar 15;57(2):307-318. Epub 2018 Nov 15.

Neuroradiology Division, Department of Radiology and Imaging Sciences, University of Utah Health Sciences Center, 30 North, 1900 East, #1A071, Salt Lake City, UT 84132-2140, USA.

Vascular disorders of the spine are more rare than cerebral vascular entities but can result in significant morbidity. These lesions frequently demonstrate distinguishing characteristics by imaging that are imperative for the radiologist to recognize to properly guide diagnosis and treatment. We review distinguishing imaging characteristics for spinal vascular malformations, spinal emergencies, and spinal vascular masses. Read More

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Intramedullary and intratumoral hemorrhage in spinal hemangioblastoma: Case report and review of literature.

Surg Neurol Int 2018 4;9:250. Epub 2018 Dec 4.

Department of Neurosurgery, Tokyo Metropolitan Police Hospital, Tokyo, Japan.

Background: Intramedullary hemorrhages involving spinal hemangioblastomas are rare. They are frequently associated with devastating neurologic outcomes, despite with emergent surgical intervention. Here, we presented an example of an intramedullary hemorrhage occurring in a spinal hemangioblastoma, where the patient markedly improved with surgery. Read More

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December 2018

Man With Left-Sided Neck Pain.

Ann Emerg Med 2018 12;72(6):e119-e120

Department of Emergency Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

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December 2018

The Application of FLOW 800 ICG Videoangiography Color Maps for Neurovascular Surgery and Intraoperative Decision Making.

World Neurosurg 2019 Feb 5;122:e186-e197. Epub 2018 Oct 5.

Department of Neurological Surgery, Goodman Campbell Brain and Spine and Indiana University, Indianapolis, Indiana, USA. Electronic address:

Background: Indocyanine green (ICG) videoangiography can assess cerebral blood flow, but results are primarily qualitative. FLOW 800 software measures fluorescence dynamics and creates a semiquantitative color delay map for assessment of relative sequence of blood flow within the vasculature.

Methods: We retrospectively reviewed 23 consecutive patients for whom FLOW 800 ICG videoangiography was used. Read More

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February 2019

Teaching NeuroImages: CNS hemangioblastomas in von Hippel-Lindau disease with exon 3 deletion.

Neurology 2018 08;91(6):e601-e602

From the Departments of Diagnostic Radiology (C.-C.C., Y.-S.T.) and Pediatrics (L.-W.C.), National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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Microsurgical Resection of Spinal Cord Hemangioblastoma: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Dec;15(6):E88-E89

Semmes Murphey Neurologic & Spine Institute, Memphis, Tennessee.

This video demonstrates microsurgical resection of spinal cord hemangioblastoma. Hemangioblastomas are rare, benign, highly vascularized tumors classified as grade I according to World Health Organization classification systems. About 3% of all intramedullary tumors are hemangioblastomas. Read More

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December 2018

Microsurgical Resection of Medulla Oblongata Hemangioblastoma: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Nov;15(5):E64-E65

Semmes Murphey Neurologic & Spine Institute, Memphis, Tennessee.

This video demonstrates the microsurgical resection of brainstem hemangioblastoma. The patient is a 32-yr-old woman with Von Hippel Lindau syndrome who presented with quadriparesis and inability to swallow. Magnetic resonance imaging (MRI) of the neuroaxis revealed a brainstem cystic lesion with contrast-enhancing tumor nodule right along the posterior aspect of the lower part of medulla oblongata. Read More

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November 2018

Embolization through the thyrocervical trunk: vascular anatomy, variants, and a case series.

J Neurointerv Surg 2018 Oct 29;10(10):1012-1018. Epub 2018 Mar 29.

Department of Interventional Neuroradiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Background And Purpose: The thyrocervical trunk (TCT) is the second ascending branch of the subclavian artery. It is considered a 'border territory' between interventional vascular radiology and interventional neuroradiology because it gives rise to branches both cervical and to the upper limbs. We describe the TCT branches anatomy, the most frequent variants, and expose eight endovascular procedures performed through the thyrocervical trunk. Read More

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October 2018

Benefits and Limitations of Indocyanine Green Fluorescent Image-Guided Surgery for Spinal Intramedullary Tumors.

Oper Neurosurg (Hagerstown) 2017 12;13(6):746-754

Department of Neurosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan.

Background: Intraoperative image guidance using near-infrared indocyanine green videoangiography (ICG-VA) has been used to provide real-time angiographic images during vascular or brain tumor surgery, and it is also being used for spine surgery.

Objective: To further investigate the benefits and limitations of ICG-VA image-guided surgery for spinal intramedullary tumors through retrospective study.

Methods: ICG-VA was used in 48 cases that were treated surgically over the past 5 yr. Read More

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December 2017

Sporadic Intradural Extramedullary Hemangioblastoma of the Cauda Equina: Case Report and Literature Review.

World Neurosurg 2018 Jan 28;109:436-441. Epub 2017 Oct 28.

Department of Neurosurgery, Good Samaritan Regional Medical Center, Corvallis, Oregon, USA.

Background: Spinal hemangioblastomas account for 1%-5% of all spinal cord tumors. Although spinal hemangioblastomas are rare, it is exceedingly rare to have a case of intradural extramedullary hemangioblastoma of the spine, especially in isolation without von Hippel-Lindau syndrome. The purpose of this report is to present a rare case of intradural extramedullary hemangioblastoma of the cauda equina and a literature review. Read More

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January 2018

Microsurgical Treatment of Sporadic and von Hippel-Lindau Disease Associated Spinal Hemangioblastomas: A Single-Institution Experience.

Asian Spine J 2017 Aug 7;11(4):548-555. Epub 2017 Aug 7.

Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India.

Study Design: Retrospective cohort study.

Purpose: To examine the clinical profile and surgical complications in patients with spinal hemangioblastomas and to evaluate the long-term outcome in them.

Overview Of Literature: Although considered to be histologically benign, hemangioblastomas may cause significant neurological deficits. Read More

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Surgery for spinal intramedullary tumors: technique, outcome and factors affecting resectability.

Neurosurg Rev 2018 Apr 17;41(2):503-511. Epub 2017 Jul 17.

Department of Neurosurgery, Alexandria University, 20 Amin Fikry Str. Raml Station, Alexandria, 21131, Egypt.

Intramedullary spinal cord tumors (IMSCTs) are relatively infrequent lesions with ependymomas and astrocytomas representing the most common types. Microsurgical resection is established as the treatment of choice for these challenging lesions. We reviewed the surgical outcome of 29 cases operated for IMSCTs by the same surgeon between 2009 and 2015. Read More

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Intraosseous hemangioblastoma of the cervical spine: case report.

J Neurosurg Spine 2017 Sep 30;27(3):312-315. Epub 2017 Jun 30.

Pathology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.

A 69-year-old woman presented with bilateral upper-extremity radiculopathy and neck pain after a mechanical fall. Admission CT and MRI of the cervical spine demonstrated a pathological C-4 fracture. Subsequent malignancy workup was negative. Read More

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September 2017