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Surg Neurol Int 2018 23;9:211. Epub 2018 Oct 23.

Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, Illinois, USA.

Background: Ependymomas represent 50-60% of all brain and central nervous system tumors. Previous lumbar spine surgery for resection of an ependymoma should not be considered a relative contraindication for the administration of epidural/subarachnoid anesthesia to patients in labor.

Case Description: A 34-year-old G1P0, who underwent resection of an L1-L3 intramedullary ependymoma 8 years previously, presented in active labor with residual left leg numbness and tingling. Read More

J Neurosurg Spine 2018 Oct 1:1-7. Epub 2018 Oct 1.

OBJECTIVEThe intraoperative differentiation of ependymomas from astrocytomas is important because neurosurgical strategies differ between these two tumor groups. Previous studies have reported that the diagnostic accuracy of intraoperative frozen sections of intracranial central nervous system (CNS) tumors is higher than 83%-97%, whereas that for spinal intramedullary tumors remains unknown. Herein, authors tested the hypothesis that intraoperative frozen-section diagnosis is the gold standard for a differential diagnosis of intramedullary spinal cord tumors. Read More

Med J Armed Forces India 2018 Oct 5;74(4):407-409. Epub 2017 Oct 5.

Classified Specialist (ENT), Command Hospital (Central Command), Lucknow, India.

Neurofibromatosis is a neurocutaneous, tumor predisposing, inheritable disorder characterized by tumors of the brain and spine and the presence of skin lesions. The most important tumors associated with neurofibromatosis are vestibular nerve schwannomas, with others being meningiomas and ependymomas. The cord is also affected by tumors, ependymoma being the commonest, besides meningiomas and schwannomas. Read More

Spinal Cord Ser Cases 2018 6;4:99. Epub 2018 Nov 6.

3Department of Radiology, Institute of Human Behaviour and Allied Sciences, Delhi, India.

Introduction: Schwannomas at an intramedullary location constitute only 0.3% of primary spinal tumors. Those in the conus are extremely rare, especially in the absence of neurofibromatosis, with only 12 cases reported in the literature so far, excluding the present case. Read More

Asian Spine J 2019 Feb 24;13(1):119-125. Epub 2018 Oct 24.

Department of Neurosurgery, University Hospital Complex of Badajoz, Badajoz, Spain.

Study Design: A retrospective study.

Purpose: We report our experience with 5-aminolevulinic acid (5-ALA)-assisted resection of spinal cord ependymomas in adults.

Overview Of Literature: Ependymoma is the most frequent primary spinal cord tumor in adults. Read More

World Neurosurg 2019 Jan 12;121:239-242. Epub 2018 Oct 12.

Craniospinal Surgery Center, Ankara, Turkey.

Background: Spinal cord ependymomas are the most frequent primary intramedullary tumors of the cord in middle age (40-60 years of age). Myxopapillary ependymomas are low-incidence tumors and occur in the cauda equina and conus medullaris. They are typically described as fleshy, sausage-shaped, vascular lesions. Read More

Mymensingh Med J 2018 Jul;27(3):665-668

Dr Kohinoor Jahan Shyamaly, Resident Phase-B, Department of General Paediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Primitive neuroectodermal tumors are malignant tumor of pluripotent cells of neural crest. It has diverse clinical presentation and aggressive clinical behaviour. Clinical features may provide some clue but imaging studies such as MRI of brain; tissue histopathology, immune histochemistry and cytogenetic are essential to confirm the diagnosis. Read More

Clin Nucl Med 2018 Sep;43(9):e319-e321

A 49-year-old woman presented to the emergency room with subacute paraparesis associated with bilateral cervicobrachial neuralgia. Brain and spine MRI revealed a heterogeneous hypervascular pineal tumor and a multifocal thoracolumbar intradural-extramedullary infiltrate with signs of medullary compression. C7-T2 laminectomy was performed on the same day for medullary decompression, allowing for partial lesion excision. Read More

J Neurosci Rural Pract 2018 Jul-Sep;9(3):354-358

Department of Neurosurgery, University Hospital Center Zagreb, Zagreb, Croatia.

Aim: Spinal ependymomas are among the most common intramedullary neoplasms in both adults and children. While surgical resection is the golden treatment standard, the role chemotherapy and radiotherapy have in patients with spinal ependymomas remains unclear. The aim of this study is to determine the predictors of functional outcome following spinal ependymoma resection to single out patients that may require adjuvant therapy. Read More

Praxis (Bern 1994) 2018 Feb;107(5):277-280

1 Hausarztpraxis, Zürich.

Eur Spine J 2018 07 30;27(Suppl 3):436-439. Epub 2018 Jan 30.

Department of Neurosurgery, Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou, 310009, China.

Background: Standard fluoroscopic guidance (C-arm fluoroscopy) has been routinely used for intraoperative localization of spinal level for surgical removal of intraspinal tumour, while it is not suitable for selected patients, e.g. pregnant women, who need to avoid radiation exposure. Read More

J Spine Surg 2017 Dec;3(4):727-731

Department of Neurosurgery, St Vincent's Hospital, Sydney, Australia.

Ependymomas are neuroectodermal tumours arising from the ependymal lining of the ventricles and central canal of the spinal cord. Intradural extramedullary (IDEM) ependymomas which are multifocal, and/or anaplastic (WHO grade III) at presentation are exceedingly rare. We present the second case of multifocal anaplastic IDEM ependymoma in the literature. Read More

J Spine Surg 2017 Dec;3(4):697-701

Department of Neurosurgery, University Hospital of Nice, Hôpital Pasteur, Nice, France.

Myxopapillary ependymoma is a rare tumour of the central nervous system (CNS); this subtype of ependymoma occurs most frequently in cauda equina, conus medullaris or filum terminale. The treatment consists of complete removal of the tumour including its capsule when possible since it is usually a solitary lesion. Non-Hodgkin lymphoma of the CNS is found in only 1. Read More

World Neurosurg 2018 Mar 5;111:e703-e709. Epub 2018 Jan 5.

Department of Neurosurgery, Hannover Medical School, Hannover, Germany; Department of Neurosurgery, Cologne Merheim Hospital, University of Witten/Herdecke, Cologne, Germany.

Background: Ependymomas are rare central nervous system tumors. Local tumor distribution in the central nervous system depends on age: among adults, ependymomas occur mostly in the spinal cord, whereas among children, intracranial manifestations are more common. To date, there are no prospective studies about treatment strategies for ependymomas. Read More

Spine (Phila Pa 1976) 2018 05;43(9):E525-E530

Department of Orthopaedic Surgery, Nagoya University, Nagoya, Aichi, Japan.

Study Design: Retrospective multicenter study.

Objective: The goal of this study is to determine the characteristic imaging features of spinal ependymoma in a review of magnetic resonance imaging (MRI) data for a large series of surgically proven cases.

Summary Of Background Data: Common spinal intramedullary neoplasms are mostly ependymomas and comprise 50% to 60% of spinal neuroepithelial tumors in adults. Read More

Aerosp Med Hum Perform 2017 Oct;88(10):970-973

McCoy RP. You're the flight surgeon: myxopapillary ependymoma. Aersop Med Hum Perform. Read More

J Neurosurg Spine 2017 Nov 8;27(5):518-527. Epub 2017 Sep 8.

Departments of 1 Orthopedic Surgery and.

OBJECTIVE A number of studies have reported that surgery for cervical intramedullary tumors via the posterior approach can result in postoperative sagittal malalignment of the cervical spine; however, the risk factors remain unclear. The purpose of this study was to investigate the changes in cervical spinal alignment after surgery for cervical intramedullary tumors in adults and to elucidate the risk factors for cervical spinal sagittal misalignment. METHODS Data for the period from April 2001 to December 2011 for all adults who had undergone surgery for cervical intramedullary spinal cord tumors at a single institution were retrospectively analyzed to determine the postoperative changes in cervical spine alignment. Read More

Neurosurg Rev 2018 Apr 17;41(2):503-511. Epub 2017 Jul 17.

Department of Neurosurgery, Alexandria University, 20 Amin Fikry Str. Raml Station, Alexandria, 21131, Egypt.

Intramedullary spinal cord tumors (IMSCTs) are relatively infrequent lesions with ependymomas and astrocytomas representing the most common types. Microsurgical resection is established as the treatment of choice for these challenging lesions. We reviewed the surgical outcome of 29 cases operated for IMSCTs by the same surgeon between 2009 and 2015. Read More

NMC Case Rep J 2016 Oct 7;3(4):111-114. Epub 2016 Sep 7.

Department of Neurosurgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, 565-0871, Osaka, Japan.

Spinal intradural extramedullary inflammatory pseudotumor (IPT) is an extremely rare entity. Spontaneous shrinking of a spinal IPT has never been reported. A case of an IPT of the cauda equina that regressed spontaneously is presented. Read More

NMC Case Rep J 2016 Jul 16;3(3):91-95. Epub 2016 May 16.

Department of Neurosurgery, The Jikei University School of Medicine, Tokyo, Japan.

We present a rare case of spontaneous hemorrhage of a spinal ependymoma in the filum terminale presenting with acute cauda equina syndrome. A 16-year-old male presented with a sudden onset of severe back pain that began 10 days before hospitalization. This symptom progressed, followed by development of decreased sensation in the lower extremities, bladder dysfunction, and motor weakness that advanced to an inability to walk. Read More

Intractable Rare Dis Res 2017 May;6(2):128-131

Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA, USA.

A 7-month-old boy presented with gastrointestinal disturbance, mild neurologic deficit of the left lower extremity and levo-scoliosis of the thoracic spine. Magnetic resonance imaging demonstrated a large intramedullary lesion involving the thoracic spine, from level T1 to T11. Histologic analysis showed a glial tumor with fibrillary processes arranged in radial pattern around mucoid fibrovascular cores with a high proliferative index (focally up to 80%) and prominent vascular endothelial hyperplasia. Read More

Int J Surg Pathol 2017 Oct 29;25(7):644-647. Epub 2017 May 29.

1 National Institute of Mental Health and Neurosciences, Bangalore, India.

Ependymomas are glial neoplasms with rare cases exhibiting neuronal differentiation. We describe a case of spinal anaplastic ependymoma with ganglionic differentiation in a 28-year-old woman. The ganglionic component was labeled by synaptophysin, whereas the rest of the tumor showed features of an anaplastic ependymoma. Read More

Cureus 2017 Mar 6;9(3):e1082. Epub 2017 Mar 6.

Department of Nephrology, Shifa International Hospital, Islamabad, Pakistan.

Patients with spinal abnormalities infrequently present with intradural intramedullary bleeding. The more common causes include spinal trauma, arteriovenous malformations and saccular aneurysms of spinal arteries. On occasion, spinal cord tumors either primary or metastatic may cause intramedullary bleed with ependymoma of the conus medullaris. Read More

Clin Imaging 2017 Jul - Aug;44:12-15. Epub 2017 Mar 30.

Hematology-Oncology Division, Schneider Children's Medical Center of Israel, Petach Tikva, Israel, 14 Kaplan Street, PO Box 559, Petach Tikvah 49202, Israel.

Objective: Relapse of ependymoma in childhood portends a grave prognosis. While the detection of local recurrence is usually simple, spotting leptomeningeal metastasis might be challenging. We aimed to evaluate possible "hotspots" where metastasis tend to appear. Read More

Eur Spine J 2017 05 30;26(Suppl 1):222-224. Epub 2017 Mar 30.

Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.

Introduction: We report a rare case with multiple intradural-extramedullary spinal ependymomas with different histological features.

Case Report: A 26-year-old female presented to our hospital because of difficulty in walking due to progressive paresis. Magnetic resonance imaging of the thoracic spinal cord showed multiple spinal cord tumors. Read More

Clin Spine Surg 2017 04;30(3):102-111

Department of Neurosurgery, Oncology Education and Research Hospital, Ankara, Turkey.

Ependymomas are the most common gliomas of the conus and lower cord, with the cervical cord being the second most common location. These tumors can extend upward 3-4 vertebra, and some ependymomas can extend up over 15 segments. Depending on many factors, such as tumor size, lateralization, kyphotic deformity, and lordosis state, there are several posterior surgical options, including laminectomy, laminectomy and lateral mass screw-plate, and laminoplasty. Read More

Neurocirugia (Astur) 2017 Jul - Aug;28(4):190-196. Epub 2017 Feb 23.

Servicio de Neurocirugía, Hospital Universitari de Girona Dr. Josep Trueta, Girona, España.

A dark pigmented intramedullary mass is very rarely encountered in daily practice, and poses a diagnostic challenge. Several entities have to be considered, including melanin-containing tumours (melanotic ependymoma and melanotic schwannoma) and melanocyte-containing tumours (melanocytoma, primary melanoma and melanoma metastases). The case is presented of a 47 year-old male with a pigmented intramedullary tumour located at T7-T8 level. Read More

World Neurosurg 2017 Apr 13;100:710.e1-710.e5. Epub 2017 Feb 13.

Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.

Spontaneous acute subarachnoid hemorrhage (SAH) from lumbar ependymoma in children is rare. We report a case of a 14-year-old boy who developed sudden radicular low back pain while playing baseball. He was initially managed conservatively in a local hospital for suspected lumbar disc herniation, but he later developed meningeal symptoms and fever before being referred to our hospital. Read More

Radiother Oncol 2017 03 12;122(3):362-367. Epub 2017 Jan 12.

Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, France; Department of Radiation Oncology, Institut Claudius Regaud, Institut Universitaire du Cancer de Toulouse - Oncopole, France.

Purpose: To investigate the patterns of failure after radiotherapy for pediatric intracranial ependymoma and their correlation with dose parameters.

Methods: Between 2000 and 2013, 206 patients were treated in France. MRI scans at relapse were registered to the original planning CTs for topographic analysis of failure patterns. Read More

Neurosurg Focus 2017 Jan;42(1):E11

Departments of 1 Neurological Surgery and.

OBJECTIVE Cone-beam CT (CBCT) image guidance technology has been widely adopted for spine radiosurgery delivery. There is relatively little experience with spine radiosurgery for intradural tumors using CBCT image guidance. This study prospectively evaluated a series of intradural spine tumors treated with radiosurgery. Read More

World Neurosurg 2017 Mar 29;99:812.e21-812.e26. Epub 2016 Dec 29.

Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA; Semmes-Murphey Neurologic & Spine Institute, Memphis, Tennessee, USA. Electronic address:

Myxopapillary ependymoma (MPE) is a slow-growing tumor, occurring most often in adults. It originates from the filum terminale in the area of the conus medullaris and cauda equina and is considered a benign lesion. Despite this classification, however, recurrence after both partial and gross total resection is well known. Read More

J Neurosurg Spine 2017 Apr 16;26(4):474-482. Epub 2016 Dec 16.

OBJECTIVE People with neurofibromatosis Type 2 (NF2) have a genetic predisposition to nervous system tumors. NF2-associated schwannomas stabilize or decrease in size in over half of the patients while they are receiving bevacizumab. NF2 patients treated with bevacizumab for rapidly growing schwannoma were retrospectively reviewed with regard to ependymoma prevalence and response to treatment. Read More

J Neurooncol 2016 10 16;130(1):229-236. Epub 2016 Aug 16.

Department of Radiology, Spine and Spinal Cord Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 135-720, South Korea.

Cavernous angiomas of the spinal cord exhibit imaging characteristics that may overlap with those of hemorrhagic ependymoma. In the present study, we aimed to identify specific magnetic resonance imaging (MRI) findings that could be used to differentiate cavernous angioma from hemorrhagic ependymoma, and to evaluate serial MRI changes in cases of cavernous angioma. We retrospectively evaluated MR images of spinal cord tumors collected at our hospital from 2007 to 2015. Read More

Magn Reson Imaging Clin N Am 2016 Nov;24(4):811-821

Department of Neurosurgery, University of Tennessee Health Science Center, 847 Monroe Avenue, Memphis, TN 38163, USA; Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital, 848 Adams Avenue, Memphis, TN 38103, USA; Division of Neurosurgery, St. Jude's Children's Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Semmes Murphey Neurologic & Spine Institute, 6325 Humphreys Boulevard, Memphis, TN 38120, USA.

Cerebellar tumors are the most common group of solid tumors in children. MR imaging provides an important role in characterization of these lesions, surgical planning, and postsurgical surveillance. Preoperative imaging can help predict the histologic subtype of tumors, which can provide guidance for surgical planning. Read More

Turk Neurosurg 2018 ;28(1):158-163

Ministry of Health, Kayseri Training and Research Hospital, Department of Neurosurgery, Kayseri, Turkey.

The surgical approaches for spinal tumors, to a great extent, have been developed in accordance with the developments in medical technology. Today, many surgical techniques are implemented as anterior, anterolateral, posterior, posterolateral and combined approaches. Due to its low morbidity, the posterior approach is the more preferred one. Read More

Neurosurg Focus 2016 Aug;41(2):E8

Institute of Medical Sciences, Faculty of Medicine, University of Toronto;

OBJECTIVE The objective of this study was to identify clinically relevant predictors of progression-free survival and functional outcomes in patients who underwent surgery for intramedullary spinal cord tumors (ISCTs). METHODS An institutional spinal tumor registry and billing records were reviewed to identify adult patients who underwent resection of ISCTs between 1993 and 2014. Extensive data were collected from patient charts and operative notes, including demographic information, extent of resection, tumor pathology, and functional and oncological outcomes. Read More

BMJ Case Rep 2016 Jul 28;2016. Epub 2016 Jul 28.

Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India.

An 8-year-old boy presented with a 1-year history of low backache, followed by paraparesis and urinary incontinence. MRI of the thoracic spine revealed an intramedullary, intensely contrast-enhancing lesion extending from T11 to L1 vertebral level, consistent with astrocytoma, ependymoma or haemangioblastoma. A diagnosis of intramedullary chordoma was made on tissue biopsy and immunohistochemical study. Read More

Handb Clin Neurol 2016 ;136:689-706

Dent Neurologic Institute, Amherst, NY, USA. Electronic address:

Intramedullary, intradural/extramedullary, and extradural spine tumors comprise a wide range of neoplasms with an even wider range of clinical symptoms and prognostic features. Magnetic resonance imaging (MRI), commonly used to evaluate the spine in patients presenting with pain, can further characterize lesions that may be encountered on other imaging studies, such as bone scintigraphy or computed tomography (CT). The advantage of the MRI is its multiplane capabilities, superior contrast agent resolution, and flexible protocols that play an important role in assessing tumor location, extent in directing biopsy, in planning proper therapy, and in evaluating therapeutic results. Read More

Neuroimaging Clin N Am 2016 Aug;26(3):459-69

Department of Neurosurgery, University of Tennessee Health Science Center, 847 Monroe Avenue, Memphis, TN 38163, USA; Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital, 848 Adams Avenue, Memphis, TN 38103, USA; Division of Neurosurgery, St. Jude's Children's Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Semmes Murphey Neurologic & Spine Institute, 6325 Humphreys Boulevard, Memphis, TN 38120, USA.

Cerebellar tumors are the most common group of solid tumors in children. MR imaging provides an important role in characterization of these lesions, surgical planning, and postsurgical surveillance. Preoperative imaging can help predict the histologic subtype of tumors, which can provide guidance for surgical planning. Read More

Korean J Spine 2016 Mar 31;13(1):33-6. Epub 2016 Mar 31.

Department of Neurosurgery, Acıbadem University Faculty of Medicine, Istanbul, Turkey.

A 32-year-old man presented with gradually increasing bilateral buttock pain. He had intermittent claudication. Multiple, homogenously enhanced intradural extramedullary lesions at L2-L3 and L5-S1 levels were observed on magnetic resonance imaging. Read More

Childs Nerv Syst 2016 Aug 27;32(8):1441-7. Epub 2016 Apr 27.

Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 262 Danny Thomas Place (MS 220), Memphis, TN, 38105, USA.

Purpose: Imaging descriptions of posterior fossa ependymoma in children have focused on magnetic resonance imaging (MRI) signal and local anatomic relationships with imaging location only recently used to classify these neoplasms. We developed a quantitative method for analyzing the location of ependymoma in the posterior fossa, tested its effectiveness in distinguishing groups of tumors, and examined potential associations of distinct tumor groups with treatment and prognostic factors.

Methods: Pre-operative MRI examinations of the brain for 38 children with histopathologically proven posterior fossa ependymoma were analyzed. Read More

J Clin Neurosci 2016 Aug 4;30:160-162. Epub 2016 Apr 4.

University of Arizona, Department of Surgery, Division of Neurosurgery, 1501 N. Campbell Avenue, Tucson, AZ 85724-5070, USA.

Osteoradionecrosis is a known complication following radiation therapy, presenting most commonly in the cervical spine as a delayed consequence of radiation that is often necessary in the management of head and neck cancers. In contrast, osteoradionecrosis has rarely been described in the lumbar spine. Here we describe, to our knowledge, the first reported case of lumbar spine osteoradionecrosis, after adjuvant radiation for a primary spinal cord tumor, leading to progressive degenerative scoliosis which required subsequent operative management. Read More

Eur Spine J 2016 05 25;25 Suppl 1:239-44. Epub 2016 Mar 25.

Department of Neurological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

Purpose: Symptoms of cauda equina syndrome due to ependymoma in the conus medullaris or filum terminale develop slowly. However, hemorrhagic change inside spinal tumors can induce acute neurologic decline. Here, we report a case of posttraumatic hemorrhage inside a filum terminale myxopapillary ependymoma presenting as acute neurologic decline, which had a positive prognosis after surgical resection. Read More

J Pediatr Neurosci 2015 Oct-Dec;10(4):396-8

Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.

The authors present a case of a 15-year-old male patient who presented with gradually progressive quadriparesis for 3 years. Magnetic resonance imaging of the spine was suggestive of heterogeneously enhancing mass lesion extending from cervicomedullary junction to conus. This holocord spinal tumor was excised in a single stage with standard microsurgical technique. Read More

Clin Radiol 2016 May 2;71(5):499.e9-15. Epub 2016 Mar 2.

Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China. Electronic address:

Aim: To characterize the magnetic resonance imaging (MRI) findings in a series of five patients with cervical and cervicothoracic intraspinal subependymomas and to increase awareness of this neoplasm.

Materials And Methods: The clinical and radiological profiles of five patients who were diagnosed with subependymoma based on histopathological findings were retrospectively studied and compared with previously reported cases. All patients underwent enhanced MRI. Read More

Neuroradiol J 2016 Feb 11;29(1):61-5. Epub 2016 Jan 11.

Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, UK.

Tanycytic ependymoma is an unusual morphological variant of WHO grade II ependymoma, typically arising from the cervical or thoracic spinal cord. Although the literature deals extensively with pathological features of this tumour entity, imaging features have not been well characterised. The purpose of this study was to review magnetic resonance imaging (MRI) features of spinal tanycytic ependymomas reported in the literature to date, exemplified by a case of a patient with tanycytic ependymoma of the conus medullaris presenting to our hospital. Read More

J Clin Neurosci 2015 Dec 23;22(12):1871-6. Epub 2015 Oct 23.

We present a rare extramedullary ependymoma with diffuse spinal metastatic disease, and review the previous reports of extramedullary spinal ependymomas. Ependymomas are the most common intramedullary spinal cord tumor in adults. These tumors rarely present as extramedullary masses. Read More

J Neurooncol 2016 Jan;126(1):165-74

Myxopapillary ependymomas (MPEs) are rare spinal tumors in children. The natural history and clinical course of pediatric MPEs are largely unknown and the indication for adjuvant therapy remains to be clarified. We performed an IRB-approved, retrospective review of children with MPEs treated at the Dana-Farber/Boston Children's Cancer and Blood Disorder Center between 1982 and 2013. Read More

Spine J 2016 Feb 30;16(2):e47. Epub 2015 Sep 30.

Ondokuz Mayis University Faculty of Medicine, Department of Radiology, Samsun, Turkey.

Global Spine J 2015 Oct 31;5(5):425-35. Epub 2015 Mar 31.

Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois, United States.

Study Design Broad narrative review. Objectives Intramedullary spinal cord tumors (IMSCT) are rare neoplasms that can potentially lead to severe neurologic deterioration, decreased function, poor quality of life, or death. As such, a better understanding of these lesions is needed. Read More