3,752 results match your criteria Imaging in Pulmonic Stenosis


Models and Techniques to Study Aortic Valve Calcification , and . An Overview.

Front Pharmacol 2022 2;13:835825. Epub 2022 Jun 2.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve interstitial cells. To develop non-surgical treatments, the molecular and cellular mechanisms of pathological calcification must be revealed. Read More

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Prevalence and Natural History of Mitral Annulus Calcification and Related Valve Dysfunction.

Mayo Clin Proc 2022 Jun;97(6):1094-1107

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. Electronic address:

Objective: To evaluate the prevalence and natural history of mitral annulus calcification (MAC) and associated mitral valve dysfunction (MVD) in patients undergoing clinically indicated echocardiography.

Methods: A retrospective review was conducted of all adults who underwent echocardiography in 2015. Mitral valve dysfunction was defined as mitral regurgitation or mitral stenosis (MS) of moderate or greater severity. Read More

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Prognostic value of systemic inflammatory response syndrome after transcatheter aortic valve implantation.

J Cardiovasc Med (Hagerstown) 2022 Jun;23(6):394-398

Department of Clinical, Internal, Anaesthesiology and Cardiovascular Sciences, 'Sapienza' University of Rome, Policlinico Umberto I, Rome, Italy.

Aims: Systemic inflammatory response syndrome (SIRS) could affect mortality after transcatheter aortic valve implantation (TAVI) up to 12 months of follow-up. The aim of this study was to evaluate the prevalence of SIRS after TAVI and its impact on all-cause mortality up to 24 months follow-up.

Methods: We retrospectively enrolled 132 patients with symptomatic severe aortic stenosis undergoing TAVI. Read More

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Multiparametric MRI identifies subtle adaptations for demarcation of disease transition in murine aortic valve stenosis.

Basic Res Cardiol 2022 05 29;117(1):29. Epub 2022 May 29.

Cardiovascular Research Laboratory, Division of Cardiology, Pulmonary Diseases and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

Aortic valve stenosis (AS) is the most frequent valve disease with relevant prognostic impact. Experimental model systems for AS are scarce and comprehensive imaging techniques to simultaneously quantify function and morphology in disease progression are lacking. Therefore, we refined an acute murine AS model to closely mimic human disease characteristics and developed a high-resolution magnetic resonance imaging (MRI) approach for simultaneous in-depth analysis of valvular, myocardial as well as aortic morphology/pathophysiology to identify early changes in tissue texture and critical transition points in the adaptive process to AS. Read More

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An Unusual Cause of Shortness of Breath: Pulmonary Vein Stenosis After Surgical Mitral Valve Replacement.

JACC Case Rep 2022 May 4;4(9):533-537. Epub 2022 May 4.

Division of Cardiology, Columbia University Irving Medical Center, New York, New York, USA.

A 79-year-old man with prior bioprosthetic mitral valve replacement presented with progressive shortness of breath and was found to have right upper pulmonary vein stenosis and paravalvular leak diagnosed with the use of multimodal imaging. The patient underwent balloon angioplasty, stenting of the pulmonary vein, and paravalvular leak closure with ultimate resolution of symptoms. (). Read More

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Transcatheter Aortic Valve Replacement for Mixed Aortic Valve Disease: A Propensity Score-Adjusted Analysis From the RISPEVA Registry.

J Invasive Cardiol 2022 Jun 6;34(6):E419-E427. Epub 2022 May 6.

Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari Piazza G. Cesare 11, Bari, Italy.

Background: The differential outcomes between pure/predominant aortic stenosis (AS) and mixed aortic valve disease (MAVD) in patients undergoing transcatheter aortic valve implantation (TAVI) are still debated.

Objective: To evaluate the comparative clinical outcomes of patients with MAVD and AS undergoing TAVI using data from the RISPEVA registry.

Methods: A total of 3263 patients were included. Read More

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Novel echocardiographic score to predict duct-dependency after percutaneous relief of critical pulmonary valve stenosis/atresia.

Echocardiography 2022 May 24;39(5):724-731. Epub 2022 Apr 24.

Paediatric Cardiology Unit, University of Campania "Luigi Vanvitelli", A.O.R.N. "Ospedali dei Colli", Naples, Italy.

Objectives: This study aimed to identify clinical, hemodynamic, or echocardiographic predictive features of persistent duct-dependency of pulmonary circulation (PDDPC) after effective percutaneous relief of pulmonary atresia with the intact ventricular septum (PA-IVS) or critical pulmonary stenosis (CPS).

Methods: From 2010 to 2021, 55 neonates with PA-IVS or CPS underwent percutaneous right ventricle (RV) decompression at our Institution. After successfully relief of critical obstruction, 27 patients (group I) showed PDDPC, whereas RV was able to support the pulmonary circulation in the remaining 28 patients (group II). Read More

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Severe Aortic Valve Stenosis and Pulmonary Hypertension: A Systematic Review of Non-Invasive Ways of Risk Stratification, Especially in Patients Undergoing Transcatheter Aortic Valve Replacement.

J Pers Med 2022 Apr 8;12(4). Epub 2022 Apr 8.

Department of Internal Medicine II, Division of Cardiology, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria.

Patients with severe aortic valve stenosis and concomitant pulmonary hypertension show a significantly reduced survival prognosis. Right heart catheterization as a preoperative diagnostic tool to determine pulmonary hypertension has been largely abandoned in recent years in favor of echocardiographic criteria. Clinically, determination of echocardiographically estimated systolic pulmonary artery pressure falls far short of invasive right heart catheterization data in terms of accuracy. Read More

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Paravalvular Leak.

Methodist Debakey Cardiovasc J 2022 1;18(1):7-9. Epub 2022 Apr 1.

Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, US.

Despite improvements and advancements in surgical technique, paravalvular leaks (PVL) continue to present a challenge when caring for patients with prosthetic valve disease. Paravalvular leaks result from dehiscence of the surgical ring from the mitral annulus. Some theories suggest that uneven distribution of collagen fibers in the mitral annulus leaves the posterior mitral annulus without a well-formed fibrous structure, which may predispose it to recurrent mechanical injury that leads to PVL. Read More

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Long-term performance of untreated fresh autologous pericardium as a valve substitute in pulmonary position.

Ann Card Anaesth 2022 Apr-Jun;25(2):164-170

Department of Radiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Background: Pulmonary regurgitation is imminent after transannular patch (TAP). We analyze the long-term performance of untreated autologous pericardium (UAP) as valve substitute at pulmonary position in patients requiring TAP.

Material And Methods: This cross-sectional study include patients operated between 2007 and 2012 (n = 92). Read More

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Pulmonary valve perforation with multiple cardiac anomalies: a case report.

BMC Cardiovasc Disord 2022 04 9;22(1):159. Epub 2022 Apr 9.

Echocardiography and Vascular Ultrasound Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, No.79, Qing-Chun Road, Hangzhou, 310003, China.

Background: Large pulmonary valve perforation, which is rarely seen with infective endocarditis, general atrophy, or congenital fenestration, often leads to potentially fatal outcomes, including heart failure.

Case Presentation: Transthoracic and transesophageal echocardiographic evaluation of a 69-year-old woman revealed a severely eccentric pulmonary regurgitation with concomitant pulmonary valve stenosis, patent ductus arteriosus, patent foramen ovale, and pulmonary artery aneurysm. In the operation, a large perforation was found in the pulmonary valve leaflet. Read More

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Transcatheter aortic valve implantation in patients with age ≤70 years: experience from two leading structural heart disease centers.

Minerva Cardiol Angiol 2022 Mar 25. Epub 2022 Mar 25.

Department of Cardiac Surgery and Heart Transplantation, San Camillo Forlanini Hospital, Rome, Italy.

Background: Transcatheter aortic valve implantation (TAVI) is emerging a an appealing management strategy for patients with severe aortic stenosis at intermediate, high or exceedingly high risk, but its risk-benefit profile in younger patients is less certain. We aimed at exploring the outlook of patients aged 70 years or less and undergoing TAVI at 2 high-volume Italian institituions.

Methods: We retrospectively collected baseline, imaging, procedural and outcome features of patients with age ≤70 years in whom TAVI was attempted at participating centers between 2012 and 2021. Read More

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New-Onset Atrial Fibrillation After Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.

JACC Cardiovasc Interv 2022 03;15(6):603-613

Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. Electronic address:

Objectives: The authors aimed to identify risk factors and outcomes associated with new-onset atrial fibrillation (NOAF) after transcatheter aortic valve replacement (TAVR).

Background: NOAF is a common complication after TAVR, although estimates of the precise occurrence are variable. This study sought to quantify the occurrence of NOAF after TAVR and to explore the outcomes and predictors associated with this complication. Read More

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Quadricuspid pulmonary valve -Case report and the comparison with quadricuspid aortic valve.

Curr Cardiol Rev 2022 Mar 22. Epub 2022 Mar 22.

Department of Pediatrics, Kindai University Nara Hospital 1248-1, Otoda, Ikoma, Nara, 630-0293, Japan.

Background Quadricuspid pulmonary valve (QPV) is a rare congenital anomaly. Simple QPV had been mainly diagnosed at the time of autopsy before 2000 and the frequency rates of QPV are approximately 0.02%-0. Read More

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Impact of Right Ventricular Pressure Load After Repair of Tetralogy of Fallot.

J Am Heart Assoc 2022 04 18;11(7):e022694. Epub 2022 Mar 18.

Department of Heart, Thoracic, Transplantation and Vascular Surgery Hannover Medical School Hannover Germany.

Background Right ventricular outflow tract (RVOT) stenosis after repair of tetralogy of Fallot has been linked with favorable right ventricular remodeling but adverse outcomes. The aim of our study was to assess the hemodynamic impact and prognostic relevance of right ventricular pressure load in this population. Methods and Results A total of 296 patients with repaired tetralogy of Fallot (mean age, 17. Read More

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Imaging characteristics and associations of left atrioventricular valve atresia and patent aortic root with lateralized atrial chambers on multidetector CT.

J Card Surg 2022 Jun 17;37(6):1574-1584. Epub 2022 Mar 17.

Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, India.

Aim: To study the imaging characteristics and the associations of left atrioventricular valve atresia with patent aortic root and lateralized atrial chambers on multidetector computed tomography (CT) angiography.

Materials And Methods: We retrospectively evaluated all the CT angiography studies performed for the evaluation of various congenital heart diseases at our center from January 2014 to December 2021. Cases with left atrioventricular valve atresia and patent aortic root with lateralized atrial chambers were identified. Read More

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Supravalvular pulmonary stenosis: A risk factor for reintervention in Noonan syndrome with pulmonary valve stenosis.

Catheter Cardiovasc Interv 2022 04 9;99(5):1538-1544. Epub 2022 Mar 9.

Department of Paediatric Cardiology, The Heart Unit, Birmingham Women's and Children's Hospital NHS Foundation Trust, Birmingham, UK.

Objectives: To assess the short- and long-term outcomes of balloon pulmonary valvuloplasty (BPV) in children with Noonan syndrome (NS).

Background: Pulmonary stenosis (PS) is the most common congenital heart lesion in NS. BPV is the accepted first line treatment in PS. Read More

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Neurological features of Noonan syndrome and related RASopathies: Pain and nerve enlargement characterized by nerve ultrasound.

Am J Med Genet A 2022 06 8;188(6):1801-1807. Epub 2022 Mar 8.

Department of Neurology and Clinical Neurophysiology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.

This study aimed to assess the nature of peripheral nervous system (PNS) involvement in three patients with Noonan syndrome (NS) or NS with multiple lentigines (NSML) as a related RASopathy, presenting primary with intractable neuropathic pain. We studied three unrelated adult patients with severe neuropathic pain and muscle weakness of the limbs. Nerve conduction studies and needle electromyography (EMG) were performed and PNS involvement was assessed by nerve ultrasound imaging, complemented with spinal magnetic resonance imaging (MRI) for the evaluation of proximal nerve segments. Read More

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Transcatheter closure of tubular patent ductus arteriosus using muscular ventricular septal defect devices in infants and small children with congestive heart failure.

Arch Cardiovasc Dis 2022 Mar 24;115(3):134-141. Epub 2022 Feb 24.

Paediatric Cardiology Services, Royal Brompton Hospital and Harefield NHS Foundation Trust, London SW3 6NP, UK; National Heart and Lung Institute, Guy Scadding Building, London SW3 6LY, UK. Electronic address:

Background: Transcatheter closure of a patent ductus arteriosus in children is widely performed to reduce symptoms and decrease the risk of endocarditis. Most arterial ducts are closed successfully with dedicated devices. However, in a tubular or "type C" patent ductus arteriosus with congestive heart failure, the occlusion is more challenging with these devices, with a higher risk of complications, such as aortic or left pulmonary stenosis and device embolization. Read More

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Physical activity and exercise recommendations for patients with valvular heart disease.

Heart 2022 Mar 2. Epub 2022 Mar 2.

Cardiovascular Clinical Academic Group, St George's University of London, London, UK

There is a paucity of studies looking at the natural history of valvular heart disease (VHD) in exercising individuals, and exercise recommendations are largely based on expert consensus. All individuals with VHD should be encouraged to avoid sedentary behaviour by engaging in at least 150 min of physical activity every week, including strength training. There are generally no exercise restrictions to individuals with mild VHD. Read More

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Timing of pulmonary valve replacement: can we use the same volumetric thresholds in repaired tetralogy of Fallot and pulmonary stenosis?

Cardiol Young 2022 Mar 2:1-6. Epub 2022 Mar 2.

Schneeweiss Adult Congenital Heart Center, Columbia University Irving Medical Center, New York, NY, USA.

The timing of pulmonary valve replacement in patients with pulmonary regurgitation following treatment of pulmonary stenosis is undefined. Although cardiac magnetic resonance-based right ventricular volumes in tetralogy of Fallot patients have been used as a guide in pulmonary stenosis patients, anatomic differences between tetralogy of Fallot and pulmonary stenosis patients complicate their application to pulmonary stenosis patients and could result in late referral for pulmonary valve replacement. We sought to determine if pulmonary stenosis patients referred for pulmonary valve replacement were at greater risk for morbidity or need for tricuspid valve intervention at the time of pulmonary valve replacement. Read More

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Computed tomographic assessment of right ventricular long axis strain for prognosis after transcatheter aortic valve replacement.

Eur J Radiol 2022 Apr 14;149:110212. Epub 2022 Feb 14.

Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA.

Objectives: To investigate the predictive value of right ventricular long axis strain (RV-LAS) derived by cardiac computed tomography angiography (CCTA) for mortality in patients with aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR).

Methods: We retrospectively included patients with severe AS undergoing TAVR (n = 168, median 79 years). Parameters of RV function including RV-LAS and RV ejection fraction (RVEF) were assessed using pre-procedural systolic and diastolic CCTA series. Read More

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Percutaneous closure of an iatrogenic ventricular septal defect associated with transcatheter aortic valve implantation.

Turk Kardiyol Dern Ars 2022 Jan;50(1):70-78

Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.

An 81-year-old man who had dyspnea was admitted to our hospital with a diagnosis of severe aortic stenosis. A transcatheter aortic valve implantation was successfully performed with a 29 mm Edwards Sapien XT valve using a transfemoral access. After the procedure, the echocardiography showed a restrictive ventricular septal defect (VSD) in the membranous septum. Read More

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January 2022

A new association of Oculoauriculovertebral spectrum and persistent fifth aortic arch -double lumen aorta: a case report.

BMC Pediatr 2022 02 21;22(1):102. Epub 2022 Feb 21.

Department of Pediatric Cardiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.

Background: Oculo-auriculo-vertebral spectrum is a heterogeneous group of genetic disorder, also known as Goldenhar Syndrome, which has several phenotypic features including craniofacial anomalies, cardiac, vertebral and central nervous system defects. Cardiovascular anomalies include ventricular septal defects, atrial septal defects, patent ductus arteriosus, Tetralogy of Fallot, double outlet right ventricle, aberrant right subclavian artery, coarctation of aorta, transposition of the great arteries, double inlet left ventricle, cor triatriatum, pulmonary artery stenosis, aortic stenosis, persistent left superior vena cava, partially or totally abnormal pulmonary venous return and bicuspid aortic valve. Persistent fifth aortic arch, also named as double lumen aortic arch, is a very rare cardivascular anomaly and usually associate other cardiac defects. Read More

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February 2022

Transcatheter aortic valve implantation in patients with chronic obstructive pulmonary disease.

Clin Cardiol 2022 02;45(2):149

Section of Interventional Cardiology, Baylor College of Medicine, Houston, Texas, USA.

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February 2022

Norwood procedure for hypoplastic left heart syndrome associated with valvular pulmonary stenosis.

Interact Cardiovasc Thorac Surg 2022 05;34(5):930-932

Department of Cardiovascular Surgery, Osaka Women's and Children's Hospital, Osaka, Japan.

Association between hypoplastic left heart syndrome and valvular pulmonary stenosis is very rare. Severity of valvular pulmonary stenosis in this setting limits management options. Consequently, patients with this condition are considered poor candidates for Norwood stage one reconstruction. Read More

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Juxtaposition of the Atrial Appendages: A Large Echocardiographic Series.

Pediatr Cardiol 2022 Jun 2;43(5):1094-1103. Epub 2022 Feb 2.

Mount Sinai Hospital, 1 Gustave L Levy Place, New York, NY, 10029, USA.

Juxtaposition of the atrial appendages is known to occur in specific congenital heart lesions. Recognition of these variants is critical in balloon atrial septostomy and atrial switch operations. There remains little clinical data on the prevalence and associations of these lesions. Read More

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Handheld Echocardiography in a Clinical Practice Scenario: Concordances Compared to Standard Echocardiographic Reports.

J Cardiovasc Imaging 2022 Jan;30(1):25-34

Division of Cardiovascular Diseases, University of British Columbia, Vancouver, Canada.

Background: The purpose of this study was to assess the utility of a handheld device (HH) used during common daily practice and its agreement with the results of a standard echocardiography study (STD) performed by experienced sonographers and echocardiographer.

Methods: A prospective follow-up was conducted in an adult outpatient echocardiography clinic. Experienced sonographers performed the STD and an experienced echocardiographer performed the HH. Read More

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January 2022