798 results match your criteria Imaging in Mucinous Cystic Neoplasms of the Pancreas


[Quality of indications in cystic lesions of the pancreas].

Chirurg 2020 Jul 8. Epub 2020 Jul 8.

Klinik für Allgemein, Viszeral- und Transplantationschirurgie, Klinikum der Universität München, Standort Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

Cystic tumors of the pancreas (PCN) have increasingly gained importance in the clinical routine as they are frequently diagnosed as an incidental finding due to the continuous improvement in cross-sectional imaging. A differentiation is made between non-neoplastic and neoplastic cysts, whereby the latter has a tendency to malignant transformation to a varying extent. Therefore, they can be considered as precursor lesions of pancreatic cancer (PDAC). Read More

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http://dx.doi.org/10.1007/s00104-020-01217-4DOI Listing

Multimodal radiomics and cyst fluid inflammatory markers model to predict preoperative risk in intraductal papillary mucinous neoplasms.

J Med Imaging (Bellingham) 2020 May 25;7(3):031507. Epub 2020 Jun 25.

Queen's University, School of Computing, Kingston, Ontario, Canada.

Our paper contributes to the burgeoning field of surgical data science. Specifically, multimodal integration of relevant patient data is used to determine who should undergo a complex pancreatic resection. Intraductal papillary mucinous neoplasms (IPMNs) represent cystic precursor lesions of pancreatic cancer with varying risk for malignancy. Read More

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http://dx.doi.org/10.1117/1.JMI.7.3.031507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315109PMC

[Clinical diagnosis and treatment characteristics of pancreatic cystic neoplasms in pediatric patients: a report of 13 cases].

Zhonghua Wai Ke Za Zhi 2020 Jul;58(7):525-529

Department of General Surgery, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430014, China.

To investigate the clinical characteristics of pancreatic cystic neoplasms in pediatric patients. The clinical data of 13 patients with pancreatic cystic neoplasm at Wuhan Children's Hospital from July 2007 to November 2019 were collected.There were 5 males and 8 females, with a mean age of 133 months(range: 9 to 170 months). Read More

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http://dx.doi.org/10.3760/cma.j.cn112139-20191122-00574DOI Listing

Giant pancreatic mucinous cystadenoma masquerading as renal hydatid disease.

Urol Ann 2020 Apr-Jun;12(2):184-186. Epub 2020 Apr 14.

Department of Urology, MIOT International, Chennai, Tamil Nadu, India.

Mucinous cystic neoplasms of the pancreas are the most common pancreatic cystic neoplasms. A 54-year-old female presented with an abdominal mass and was diagnosed to have a multilocular hydatid cyst from the left kidney by imaging. During surgery, a large thick-walled cyst with multiple loculi was seen arising from the upper pole of the left kidney and adherent to the distal pancreas and splenic vessels. Read More

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http://dx.doi.org/10.4103/UA.UA_51_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292442PMC

Nondiagnostic fine needle aspirates of the pancreas: A root cause analysis.

Cancer Cytopathol 2020 Jun 11. Epub 2020 Jun 11.

Department of Pathology, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

Background: Fine needle aspiration (FNA) of the pancreas is considered the primary and least invasive diagnostic method in the evaluation of pancreatic lesions. A nondiagnostic sample may trigger repeat FNA or a more invasive diagnostic procedure. The goal of this study was to identify the root causes of nondiagnostic samples. Read More

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http://dx.doi.org/10.1002/cncy.22301DOI Listing

Role of Cross-sectional Imaging (CT/MRI) in Characterization and Distinguishing Benign from Malignant/Potentially Malignant Cystic Lesions of Pancreas.

J Clin Imaging Sci 2020 16;10:28. Epub 2020 May 16.

Biostatistics, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

Objectives: The aim of the study was to evaluate the accuracy of computed tomography/magnetic resonance imaging (CT/MRI) in characterizing cystic lesions of the pancreas and in differentiating between benign and malignant/potentially malignant lesions.

Material And Methods: A retrospective study was performed on patients with pancreatic cystic lesions who underwent pre-operative imaging and surgery between October 2004 and April 2017 at a tertiary care teaching hospital. The images were reviewed for specific characteristics and diagnoses recorded independently by two radiologists who were blinded to the histopathological examination (HPE) report. Read More

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http://dx.doi.org/10.25259/JCIS_15_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265468PMC

[Ovarian metastases of pancreatic ductal adenocarcinomas: the clinicopathological characteristics and outcomes of 10 cases].

Zhonghua Zhong Liu Za Zhi 2020 Apr;42(4):331-335

Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.

To investigate the clinicopathological characteristics and outcomes of a series of ovarian metastases of pancreatic ductal adenocarcinoma. Data of clinical manifestation, pathological characteristic, treatment and follow-up result from ten patients with ovarian metastases of pancreatic ductal adenocarcinoma confirmed by pathology were retrospectively analyzed. The median age of onset was 46 years (38~79 years). Read More

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http://dx.doi.org/10.3760/cma.j.cn112152-20190220-00100DOI Listing

Total Pancreatectomy for Malignant Intraductal Papillary Mucinous Neoplasm (IPMN) Complicated by Gastropancreatic Fistulae.

Case Rep Surg 2020 24;2020:8547526. Epub 2020 Mar 24.

Department of Surgery, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

Background: Intraductal papillary mucinous neoplasms (IPMN) of the pancreas complicated by fistula formation to adjacent organs are an uncommon phenomenon. We present an IPMN of the pancreas with malignant transformation and multiple fistulae to the stomach and duodenum. . Read More

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http://dx.doi.org/10.1155/2020/8547526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132345PMC

The Role of Positron Emission Tomography in Clinical Management of Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Cancers (Basel) 2020 Mar 27;12(4). Epub 2020 Mar 27.

Department of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, 35122 Padua, Italy.

Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas represent a heterogeneous group of tumors, increasingly diagnosed in clinical practice. An early differential diagnosis between malignant and benign lesions is crucial to patient management and the choice of surgery or observation. The therapeutic approach is currently based on a patient's clinical, biochemical, and morphological characteristics. Read More

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http://dx.doi.org/10.3390/cancers12040807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226258PMC

[Clinical analysis and prognosis factors of malignancy in the patients with mucinous cystic neoplasms of the pancreas].

Zhonghua Wai Ke Za Zhi 2020 Mar;58(3):225-229

Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

To examine clinic pathological features of mucinous cystic neoplasms (MCN) of the pancreas and explore the prognosis factors associated with malignant transformation of MCN of the pancreas. This multicenter retrospective study included all patients with pancreatic MCN underwent surgery at Department of Pancreatic Surgery, Zhongshan Hospital of Fudan University between January 2008 and December 2018 and patients with MCN who confirmed by postoperative pathology from Multicenter Pancreatic Cystic Tumor Database. There were 50 males (14. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2020.03.011DOI Listing

[Intraoperative Pancreatoscopy to Assess the Resection Margin in Intraductal Papillary Mucinous Neoplasm-A Case Report].

Gan To Kagaku Ryoho 2019 Dec;46(13):2521-2523

Dept. of Surgery, Chiba Kaihin Municipal Hospital.

Intraductal papillary mucinous neoplasm(IPMN)of the pancreas often presents with multifocal lesions. Complete resection without residual skip lesions is essential for complete eradication of the disease. We experienced a case of IPMC in which intraoperative pancreatoscopy was used to determine the surgical margin. Read More

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December 2019

Invasive Intraductal Papillary Mucinous Neoplasms: CT Features of Colloid Carcinoma Versus Tubular Adenocarcinoma of the Pancreas.

AJR Am J Roentgenol 2020 05 4;214(5):1092-1100. Epub 2020 Mar 4.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, JHOC 3140E, 601 N Caroline St, Baltimore, MD 21287.

The purpose of this study is to compare the CT features of colloid carcinoma and tubular adenocarcinoma of the pancreas arising in association with intraductal papillary mucinous neoplasms (IPMNs). The preoperative CT images of 85 patients with histopathologically proven IPMNs and associated invasive adenocarcinoma located next to each other were retrospectively reviewed. Twenty-nine patients (34. Read More

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http://dx.doi.org/10.2214/AJR.19.21824DOI Listing

Molecular Diagnosis of Cystic Neoplasms of the Pancreas: a Review.

J Gastrointest Surg 2020 May 3;24(5):1201-1214. Epub 2020 Mar 3.

Division of Surgical Oncology, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.

Background: The prevalence of incidental pancreatic cystic neoplasms (PCNs) has increased dramatically with advancements in cross-sectional imaging. Diagnostic imaging is limited in differentiating between benign and malignant PCNs. The aim of this review is to provide an overview of biomarkers that can be used to distinguish PCNs. Read More

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http://dx.doi.org/10.1007/s11605-020-04537-2DOI Listing

Branch Duct Intraductal Papillary Mucinous Neoplasms: Recommendations for Follow-Up and Surgery.

Scand J Surg 2020 Mar 2;109(1):34-41. Epub 2020 Feb 2.

General and Pancreatic Surgery, The Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.

Background And Aims: Pancreatic cysts are increasingly diagnosed, mainly during abdominal imaging performed for other reasons. Between pancreatic cystic neoplasm, intraductal papillary mucinous neoplasms are the most common pre-malignant entities. Intraductal papillary mucinous neoplasms involving side branches overall harbor a low risk of malignancy, and in the recent past, a progressively more conservative approach has been consolidated. Read More

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http://dx.doi.org/10.1177/1457496919900414DOI Listing

MRI Combined with Magnetic Resonance Cholangiopancreatography for Diagnosis of Benign and Malignant Pancreatic Intraductal Papillary Mucinous Neoplasms.

Curr Med Imaging Rev 2019 ;15(5):504-510

Department of Pathophysiology, Medical College, Qingdao University, Qingdao, Shandong 266071, China.

Background: Intraductal papillary mucinous neoplasms (IPMNs) are among the important premalignant lesions. Early detection and intervention are critical to positive patient outcomes. Magnetic resonance imaging (MRI) can be used to evaluate the malignancy of IPMNs, and magnetic resonance cholangiopancreatography (MRCP) is recommended for follow-up of pancreatic cystic lesions. Read More

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http://dx.doi.org/10.2174/1573405614666180807113422DOI Listing
January 2019

Validation of European evidence-based guidelines and American College of Gastroenterology guidelines as predictors of advanced neoplasia in patients with suspected mucinous pancreatic cystic neoplasms.

J Gastroenterol Hepatol 2020 Jan 3. Epub 2020 Jan 3.

Department of Gastroenterology, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Background And Aim: The European evidence-based guidelines (EEG) and American College of Gastroenterology Guidelines (ACGG) have been published to guide the management of pancreatic cystic lesions. We aim to evaluate the value of both guidelines in predicting advanced pancreatic cystic lesions (A-PCLs) with preoperatively imaging-suspected cystic mucinous pancreatic neoplasms (cMNs).

Methods: One hundred ninety-eight patients who underwent resections from 2013 to 2019 for suspected cMNs were retrospectively reviewed. Read More

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http://dx.doi.org/10.1111/jgh.14973DOI Listing
January 2020
3.504 Impact Factor

The management of intraductal papillary mucinous neoplasms of the pancreas.

Minerva Chir 2019 Oct;74(5):414-421

Department of General and Pancreatic Surgery, The Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.

Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are one of the most common preneoplastic entities among pancreatic cystic neoplasms (PCN). Their incidence is increasing due to an extensive use of cross-sectional imaging, but management still remains controversial. Among IPMNs, the main duct (MD-IPMN) and mixed (MT-IPMN) types harbor a high risk of malignant degeneration requiring resection in most of cases. Read More

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http://dx.doi.org/10.23736/S0026-4733.19.08145-8DOI Listing
October 2019

Ruptured primary mucinous cystadenoma of spleen leading to mucinous ascites.

BMJ Case Rep 2019 Nov 21;12(11). Epub 2019 Nov 21.

General Surgery, Indira Gandhi Medical College, Shimla, India

Mucinous cystadenoma are rare benign mucin-producing tumours. Primary mucinous neoplasms most commonly involve ovary, pancreas or appendix. They may rupture to produce mucous ascites/pseudomyxoma peritonei. Read More

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http://dx.doi.org/10.1136/bcr-2019-231212DOI Listing
November 2019

Clinical Utility of Obtaining Endoscopic Ultrasound-Guided Fine-Needle Biopsies for Histologic Analyses of Pancreatic Cystic Lesions.

Gastroenterology 2020 02 16;158(3):475-477.e1. Epub 2019 Nov 16.

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.10.048DOI Listing
February 2020
4 Reads

Diffuse histology-proven mucinous cystic neoplasm of the pancreas: A case report and review of literature.

Int J Surg Case Rep 2019 15;64:123-127. Epub 2019 Oct 15.

Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, United States. Electronic address:

Introduction: Mucinous cystic neoplasms (MCN) are rare premalignant neoplasms of the pancreas that are typically found as single lesions in the pancreatic body and tail of women in the fifth and sixth decade of life, do not communicate with the pancreatic ductal system and are characterized by mucin-producing epithelium supported by ovarian-type stroma.

Presentation Of Case: We present here a case of diffuse pancreatic involvement by MCN in a 64-year-old woman with chronic pancreatitis. Pre-operative suspicion for MCN was low due to the multi-centric nature of the lesions and imaging/biochemical fluid analysis demonstrating connection with the pancreatic ductal architecture. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806458PMC
October 2019
1 Read

Endoscopic ultrasonography for the evaluation of pancreatic cystic neoplasms.

J Med Ultrason (2001) 2019 Oct 11. Epub 2019 Oct 11.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya, 466-8550, Japan.

Endoscopic ultrasonography (EUS) is a modality with high spatial resolution that enables comprehensive observation of the entire pancreas and plays an important role in the diagnosis of pancreatic lesions. Recent advances in diagnostic imaging methods such as ultrasound, computed tomography, and magnetic resonance imaging have increased the incidental detection of pancreatic cystic lesions (PCLs). EUS has been recognized as an essential diagnostic method for the detection and evaluation of PCLs. Read More

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http://dx.doi.org/10.1007/s10396-019-00980-0DOI Listing
October 2019
1 Read

Role of endoscopic ultrasound in the screening and follow-up of high-risk individuals for familial pancreatic cancer.

World J Gastroenterol 2019 Sep;25(34):5082-5096

Pancreatology Department, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Clichy, and Paris Diderot University, Paris 75013, France.

Managing familial pancreatic cancer (FPC) is challenging for gastroenterologists, surgeons and oncologists. High-risk individuals (HRI) for pancreatic cancer (PC) (FPC or with germline mutations) are a heterogeneous group of subjects with a theoretical lifetime cumulative risk of PC over 5%. Screening is mainly based on annual magnetic resonance imaging (MRI) and endoscopic ultrasound (EUS). Read More

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http://dx.doi.org/10.3748/wjg.v25.i34.5082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747297PMC
September 2019
7 Reads

Cystic Lesions of the Pancreas: Differential Diagnosis and Cytologic-Histologic Correlation.

Arch Pathol Lab Med 2020 01 20;144(1):47-61. Epub 2019 Sep 20.

From the Department of Pathology, Medical College of Wisconsin, Milwaukee (Drs Abdelkader, Hunt, Hartley, and Giorgadze); and the Department of Pathology, Albert Einstein College of Medicine, The Bronx, New York (Dr Panarelli).

Context.—: Pancreatic cystic lesions (PCLs) are very common, and their detection is increasing with the advances in imaging techniques. Because of the major implications for management, distinguishing between neoplastic and nonneoplastic PCLs is critical. Read More

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http://dx.doi.org/10.5858/arpa.2019-0308-RADOI Listing
January 2020
5 Reads

Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines.

Nat Rev Gastroenterol Hepatol 2019 11 16;16(11):676-689. Epub 2019 Sep 16.

Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Pancreatic cystic neoplasms (PCN) are a heterogeneous group of pancreatic cysts that include intraductal papillary mucinous neoplasms, mucinous cystic neoplasms, serous cystic neoplasms and other rare cystic lesions, all with different biological behaviours and variable risk of progression to malignancy. As more pancreatic cysts are incidentally discovered on routine cross-sectional imaging, optimal surveillance for patients with PCN is becoming an increasingly common clinical problem, highlighting the need to balance cancer prevention with the risk of (surgical) overtreatment. This Review summarizes the latest developments in the diagnosis and management of PCN, including the quality of available evidence. Read More

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http://dx.doi.org/10.1038/s41575-019-0195-xDOI Listing
November 2019
4 Reads

Role of Ancillary Testing on Endoscopic US-Guided Fine Needle Aspiration Samples from Cystic Pancreatic Neoplasms.

Acta Cytol 2020 11;64(1-2):124-135. Epub 2019 Sep 11.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Pancreatic cysts are increasingly detected on imaging studies. Accurate determination of the cyst type is important to provide appropriate care for the patients. It is also very clear that not one single modality can provide adequate diagnostic information. Read More

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http://dx.doi.org/10.1159/000502372DOI Listing
January 2020
2 Reads

Overview and comparison of guidelines for management of pancreatic cystic neoplasms.

World J Gastroenterol 2019 Aug;25(31):4405-4413

Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, New York, NY 10032, United States,

Pancreatic cysts are identified at an increasing frequency. Although mucinous cystic neoplasms represent a pre-malignant condition, the majority of these lesions do not progress to cancer. Over the last 10 years several societies have established guidelines for the diagnosis, initial evaluation and surveillance of these lesions. Read More

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http://dx.doi.org/10.3748/wjg.v25.i31.4405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710181PMC
August 2019
1 Read

"Trivial" Cysts Redefine the Risk of Cancer in Presumed Branch-Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Potential Target for Follow-Up Discontinuation?

Am J Gastroenterol 2019 10;114(10):1678-1684

Department of General and Pancreatic Surgery, The Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.

Objectives: The management of small and incidental branch duct intraductal papillary mucinous neoplasms (BD-IPMNs) still is of concern. The aim is assessing the safety of a surveillance protocol through the evaluation of their progression to malignancy.

Methods: All presumed BD-IPMNs observed from 2000 to 2016 were included. Read More

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http://dx.doi.org/10.14309/ajg.0000000000000378DOI Listing
October 2019
21 Reads

The CT fish mouth ampulla sign: a highly specific finding in main duct and mixed intraductal papillary mucinous neoplasms.

Br J Radiol 2019 Nov 28;92(1103):20190461. Epub 2019 Aug 28.

Department of Radiology, Cambridge University Hospitals, Cambridge, United Kingdom.

Objective: Main duct and mixed intraductal papillary mucinous neoplasms (IPMN) are pre-malignant cystic pancreatic neoplasms associated with pancreatic duct dilatation. Distinguishing these from benign causes of pancreatic duct dilatation is important in order to allow appropriate surveillance or surgery. A patulous duodenal papilla with extrusion of mucus at endoscopic evaluation, the endoscopic fish mouth ampulla (E-FMA) sign, is reported in main duct and mixed IPMN. Read More

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https://www.birpublications.org/doi/10.1259/bjr.20190461
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http://dx.doi.org/10.1259/bjr.20190461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849671PMC
November 2019
1 Read

Etiologic Distribution of Pancreatic Cystic Lesions Identified on Computed Tomography/Magnetic Resonance Imaging.

Pancreas 2019 09;48(8):1092-1097

From the Department of Internal Medicine, Division of Gastroenterology and Hepatology.

Objectives: This study aimed to determine the distribution of etiology of pancreatic cysts using established criteria/markers from cyst fluid analysis and cytology that have been reported to have high specificity in published literature.

Methods: A retrospective study of pancreatic cysts using an endoscopic database from March 2002 and May 2013 was conducted. Pancreatic cysts <10 mm and cysts with a history of pancreatic cancer were excluded. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001372DOI Listing
September 2019
4 Reads

Mucinous nonneoplastic cyst of the pancreas penetrates the colon causing infection: a case report.

J Med Case Rep 2019 Aug 10;13(1):264. Epub 2019 Aug 10.

Department of Surgery, National Hospital Organization Higashihiroshima Medical Center, 513 Jike, Saijo-cho, Higashihiroshima, Hiroshima, 739-0041, Japan.

Background: Mucinous nonneoplastic cyst of the pancreas is a rare disease defined as a cystic lesion lined with mucinous epithelium, supported by hypocellular stroma and not communicating with the pancreatic ducts. Mucinous nonneoplastic cyst of the pancreas has no malignant potential and does not require surgical resection or surveillance. However, its preoperative differentiation from other cystic lesions of the pancreas is difficult because of several overlapping clinical, radiological, and biochemical features. Read More

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http://dx.doi.org/10.1186/s13256-019-2160-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689156PMC
August 2019
1 Read

Trends in management and outcome of cystic pancreatic lesions - analysis of 322 cases undergoing surgical resection.

Scand J Gastroenterol 2019 Aug 19;54(8):1051-1057. Epub 2019 Jul 19.

Department of Hepato-Pancreato-Biliary Surgery, Oslo University Hospital , Oslo , Norway.

Several guidelines for the management of cystic pancreatic lesions (CPL) exists. From 2013, Oslo University Hospital adapted the European consensus guidelines (ECG) in the decision-making as to whether patients should be advised to have resection or observation for CPL. The aims of the study were to assess changes over time in the workup and diagnostic accuracy of resected CPL, and the short-term surgical outcome. Read More

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http://dx.doi.org/10.1080/00365521.2019.1642379DOI Listing
August 2019
3 Reads

A prospective study on endoscopic ultrasound for the differential diagnosis of serous cystic neoplasms and mucinous cystic neoplasms.

BMC Gastroenterol 2019 Jul 16;19(1):127. Epub 2019 Jul 16.

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Haidian District, Beijing, 100853, China.

Background: To provide criteria for the differential diagnosis of serous cystic neoplasms (SCNs) and mucinous cystic neoplasms (MCNs) by analyzing the imaging features of these two neoplasms by endoscopic ultrasound (EUS).

Methods: From April 2015 to December 2017, a total of 69 patients were enrolled in this study. All patients were confirmed to have MCNs (31 patients) or SCNs (38 patients) by surgical pathology. Read More

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http://dx.doi.org/10.1186/s12876-019-1035-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636106PMC
July 2019
2.365 Impact Factor

A pancreatic mucinous cystic neoplasm undergoing intriguing morphological changes over time and associated with recurrent pancreatitis: A case report.

Medicine (Baltimore) 2019 Jul;98(28):e16435

The 3rd Department of Internal Medicine.

Rationale: Mucinous cystic neoplasms (MCNs) are pancreatic mucin-producing cystic lesions with a distinctive ovarian-type stroma. The diagnosis is generally easy in typical cases; however, differential diagnosis is difficult in others such as in the case we report herein.

Patient Concerns: A 27-year-old woman with sudden onset of epigastric pain was referred to our hospital for suspected acute pancreatitis. Read More

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http://dx.doi.org/10.1097/MD.0000000000016435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641744PMC
July 2019
5 Reads

Deep Learning to Classify Intraductal Papillary Mucinous Neoplasms Using Magnetic Resonance Imaging.

Pancreas 2019 07;48(6):805-810

Center for Research in Computer Vision, School of Engineering and Computer Science, University of Central Florida, Orlando.

Objective: This study aimed to evaluate a deep learning protocol to identify neoplasia in intraductal papillary mucinous neoplasia (IPMN) in comparison to current radiographic criteria.

Methods: A computer-aided framework was designed using convolutional neural networks to classify IPMN. The protocol was applied to magnetic resonance images of the pancreas. Read More

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http://dx.doi.org/10.1097/MPA.0000000000001327DOI Listing
July 2019
3 Reads

Pancreatobiliary-type intraductal papillary mucinous neoplasm of the pancreas may have 2 subtypes with distinct clinicopathologic and genetic features.

Hum Pathol 2019 09 6;91:26-35. Epub 2019 Jun 6.

Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan; Institute of Liver Studies, King's College Hospital & King's College London, London SE5 9RS, United Kingdom. Electronic address:

We recently experienced cases of pancreatobiliary-type intraductal papillary mucinous neoplasms (PB-IPMNs) with imaging features resembling pancreatic ductal adenocarcinomas (PDACs), and histologic appearance of purely pancreatobiliary morphology and highly distorted papillary growth, which led to the present study aiming to systematically investigate PB-IPMNs in comparison with PDACs. Surgical cases of PB-IPMNs (n = 31) and PDACs (n = 24) were examined. PB-IPMNs were classified into monotypic tumors (n = 12; 39%) consisting of entirely high-grade pancreatobiliary-type neoplastic cells and polytypic cases (n = 19; 61%) associated with components of low-grade dysplasia and/or other histologic types (eg, gastric, intestinal, or oncocytic types). Read More

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http://dx.doi.org/10.1016/j.humpath.2019.05.010DOI Listing
September 2019
15 Reads

The diagnosis and management of intraductal papillary mucinous neoplasms of the pancreas: has progress been made?

Updates Surg 2019 Jun 7;71(2):209-216. Epub 2019 Jun 7.

Department of Surgical Oncology, Duke University, Durham, NC, 27710, USA.

Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are premalignant mucin-producing epithelial tumors that arise from the pancreatic ductal system. These cystic tumors represent 15-30% of cystic lesions of the pancreas [Basturk et al. in Am J Surg Pathol 39(12):1730-1741, 1; Ferrone et al. Read More

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http://link.springer.com/10.1007/s13304-019-00661-0
Publisher Site
http://dx.doi.org/10.1007/s13304-019-00661-0DOI Listing
June 2019
14 Reads

A rare case of pulmonary lepidic metastasis in patient with branch-type intraductal papillary mucinous carcinoma of the pancreas.

Clin J Gastroenterol 2019 Dec 23;12(6):621-625. Epub 2019 May 23.

Department of Gastroenterology, Dokkyo Medical University, 880, Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321-0293, Japan.

Pulmonary lepidic metastasis from intraductal papillary mucinous carcinoma (IPMC) of the pancreas is extremely rare. The patient was a 50s-year old male who was hospitalized in the department of respiratory in our hospital for the evaluation of ground-glass opacities in both lungs on computed tomography (CT) imaging. Steroid therapy was administered, as interstitial pneumonia was suggested; however, there was no improvement. Read More

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http://dx.doi.org/10.1007/s12328-019-00993-9DOI Listing
December 2019
4 Reads

Imaging findings for mucinous tumors of the abdomen and pelvis.

Radiologia 2019 Sep - Oct;61(5):370-387. Epub 2019 May 9.

Servicio de Radiodiagnóstico, Fundación Hospital de Jove, Gijón, Asturias, España.

This article aims to describe the imaging findings for mucinous tumors of the abdomen and pelvis, which have a similar appearance on imaging tests regardless of the organ in which they develop. Due to the high water content of mucus, the appearance of these tumors is generally similar to that of water on ultrasonography, computed tomography, and magnetic resonance imaging. Another common feature of mucin-producing tumors is that calcifications are often present. Read More

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http://dx.doi.org/10.1016/j.rx.2019.03.003DOI Listing
May 2020
5 Reads

Mucinous Non-neoplastic Cyst of the Pancreas.

Korean J Gastroenterol 2019 Apr;73(4):235-238

Departments of Pathology, Wonkwang University School of Medicine, Iksan, Korea.

Cystic neoplasms of the pancreas consist of a wide range of pathological entities and are being detected more frequently due to advances in cross-sectional imaging modalities and increasing numbers of periodic health checkups. The majority of pancreatic cystic neoplasms are intraductal papillary mucinous neoplasms, serous neoplasms, and mucinous cystic neoplasms, but recently, rare cases of mucinous non-neoplastic cyst of the pancreas (MNCP) have been reported, and despite the availabilities of modern imaging systems, such as MRI and CT, the differentiation of non-neoplastic and neoplastic cysts remains challenging. Herein, we report our experience of a 65-year-old male case with an MNCP. Read More

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http://dx.doi.org/10.4166/kjg.2019.73.4.235DOI Listing
April 2019
6 Reads

EUS-Guided Pancreatic Cyst Ablation: a Clinical and Technical Review.

Curr Gastroenterol Rep 2019 Apr 23;21(5):19. Epub 2019 Apr 23.

Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA.

Purpose Of Review: Pancreatic cystic lesions represent a growing public health dilemma, particularly as our population ages and cross-sectional imaging becomes more sensitive. Mucinous cysts carry a clinically significant risk of developing pancreatic cancer, which carries an extremely poor prognosis. Determining which cysts will develop cancer may be challenging, and surgical resection of the pancreas carries significant morbidity. Read More

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http://dx.doi.org/10.1007/s11894-019-0686-5DOI Listing
April 2019
4 Reads

An osteoclast-like giant cell tumor embedded in the mural nodule of a pancreatic mucinous cystic neoplasm: A case report and literature review.

Medicine (Baltimore) 2019 Apr;98(16):e15246

Peking University China-Japan Friendship School of Clinical Medicine.

Rationale: Mucinous cystic neoplasms (MCNs) are relatively rare lesions, accounting for 2%-5% of all exocrine pancreatic neoplasms. MCNs mainly occur in women (female:male ratio = 20:1), with a peak incidence in the 5th decade of life. Osteoclast-like giant cell tumors (OGCTs) are rare and relatively aggressive neoplasms, comprising <1% of all pancreatic carcinomas. Read More

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http://dx.doi.org/10.1097/MD.0000000000015246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494236PMC
April 2019
3 Reads

Long-term survival of a patient with advanced pancreatic cancer under adjunct treatment with extracts: A case report.

World J Gastroenterol 2019 Mar;25(12):1524-1530

Department of Methodology, Institute for Applied Epistemology and Medical Methodology (IFAEMM), Freiburg 79111, Germany.

Background: Advanced pancreatic cancer (aPC) has a poor prognosis with limited survival benefit from current standard treatment. extracts (VAE) are used by many cancer patients, showing immune-stimulating effects, improved quality of life, and a survival benefit in patients with aPC.

Case Summary: A 59-year-old architect developed epigastric pain. Read More

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https://www.wjgnet.com/1007-9327/full/v25/i12/1524.htm
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http://dx.doi.org/10.3748/wjg.v25.i12.1524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441914PMC
March 2019
18 Reads

Mucinous cystic neoplasm of the pancreas assessed with a real-time three-dimensional imaging using a transesophageal echocardiography probe.

Clin J Gastroenterol 2019 Oct 2;12(5):479-483. Epub 2019 Apr 2.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

Ultrasonographic imaging techniques have been rapidly developing. The new transesophageal echocardiography (TEE) system made it possible to obtain the real-time three-dimensional (3D) image of the cardiac system through the esophagus, that can be applied to the field of gastroenterology. We herein present a case of 72-year-old woman who was referred for evaluation of an incidentally found cystic lesion in the tail of the pancreas. Read More

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http://dx.doi.org/10.1007/s12328-019-00975-xDOI Listing
October 2019
3 Reads

Impact of endoscopic ultrasound on diagnosis and management of presumed mucinous neoplasms when done for pancreatic cyst morphology change on non-invasive surveillance imaging.

Endosc Int Open 2019 Apr 15;7(4):E389-E395. Epub 2019 Mar 15.

Department of Digestive Diseases, Yale School of Medicine, New Haven, CT.

 Guidelines for management of presumed neoplastic pancreatic cysts have encouraged noninvasive imaging for low-risk surveillance, while reserving endoscopic ultrasound for worrisome features including morphologic change. We aim to study the impact of endoscopic ultrasound on diagnosis and management compared with non-invasive imaging.  A single-institution pancreatic cyst database was retrospectively queried for patients who underwent endoscopic ultrasound for the indication of change in cyst morphology. Read More

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http://dx.doi.org/10.1055/a-0824-6240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420337PMC
April 2019
16 Reads

Intraductal papillary mucinous neoplasm of the main duct in a patient with pancreas divisum.

Rev Esp Enferm Dig 2019 Apr;111(4):322

Cirugía General, Complejo Hospitalario de Navarra.

Pancreas divisum is a congenital anomaly present in 5-10% of the population and is usually asymptomatic. Pancreatic intraductal papillary mucinous neoplasms (IPMN) are mucinous cystic tumors that have malignant potential and are classified according to their location as IPMN of the main duct, branch duct or mixed type. Larger lesions and those originating in the main duct have an increased risk of malignancy. Read More

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http://dx.doi.org/10.17235/reed.2019.5959/2018DOI Listing
April 2019
9 Reads

Are BRCA1 and BRCA2 gene mutation patients underscreened for pancreatic adenocarcinoma?

J Surg Oncol 2019 May 12;119(6):777-783. Epub 2019 Jan 12.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

Background: Breast cancer (BRCA) mutations account for the highest proportion of hereditary causes of pancreatic ductal adenocarcinoma (PDAC). Screening is currently recommended only for patients with one first-degree relative or two family members with PDAC. We hypothesized that screening all BRCA1/2 patients would identify a higher rate of pancreatic abnormalities. Read More

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http://dx.doi.org/10.1002/jso.25376DOI Listing
May 2019
30 Reads

[Cystic lesions of the pancreas : Differential diagnostics and treatment].

Authors:
J Rosendahl P Michl

Internist (Berl) 2019 03;60(3):219-225

Klinik für Innere Medizin I, Universitätsklinikum Halle (Saale), Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland.

Cystic space-occupying lesions of the pancreas represent incidental findings in most cases. As there is a potential risk of malignant transformation further evaluation of the lesions as well as a follow-up of these patients is usually recommended. Before this work-up is initiated the clinical situation of the patient as a whole and comorbidities, age and personal preferences have to be taken into account. Read More

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http://dx.doi.org/10.1007/s00108-018-0547-6DOI Listing
March 2019
6 Reads