880 results match your criteria Imaging in Mucinous Cystic Neoplasms of the Pancreas

MR quantitative 3D shape analysis helps to distinguish mucinous cystic neoplasm from serous oligocystic adenoma.

Diagn Interv Radiol 2022 May;28(3):193-199

Department of Radiology, Zhongshan Hospital, Fudan University, and Shanghai Institute of Medical Imaging, Shanghai, China.

PURPOSE We aimed to assess the performance of quantitative 3D shape analysis in the differential diagno- sis of pancreatic serous oligocystic adenoma (SOA) and mucinous cystic neoplasm (MCN). METHODS Four hundred thirty-two patients diagnosed with serous cystic neoplasms (SCNs) or MCNs were retrospectively reviewed from August 2014 to July 2019 and finally 87 patients with MCNs (n = 45) and SOAs (n = 42) were included. Clinical data and magnetic resonance morphologic fea- tures with 3D shape analysis of lesions (shape sphericity, compacity, and volume) were recorded and compared between MCNs and SOAs according to the pathology. Read More

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Cystic Lesions of the Pancreas: Is Apparent Diffusion Coefficient Value Useful at 3 T Magnetic Resonance Imaging?

J Comput Assist Tomogr 2022 May-Jun 01;46(3):363-370. Epub 2022 Apr 8.

From the Department of Diagnostic Imaging, Pisa University Hospital.

Objective: The objective of this study is to determine the role of apparent diffusion coefficient (ADC) value at 3T magnetic resonance imaging (MRI) in the characterization of pancreatic cystic lesions.

Methods: We retrospectively selected a total number of 223 patients with a conclusive diagnosis of pancreatic cystic lesion, previously undergoing MR examination on a 3 T system. The MRI protocol first included axial T1/T2-weighted sequences and magnetic resonance cholangiopancreatography. Read More

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Current Evidence in the Management of Premalignant Cystic Lesions of the Pancreas in Patients Undergoing Liver Transplantation.

Pancreas 2022 02;51(2):117-120

From the Department of Surgery, Section of Hepatobiliary, Pancreatic and Transplant Surgery, University of Alberta Hospital, Edmonton, Canada.

Abstract: Incidental premalignant pancreatic cystic lesions (pPCLs) are increasingly being detected in patients undergoing orthotopic liver transplantation (OLT). The impact of chronic immunosuppression upon pPCLs may elevate risk of progression to pancreatic cancer. This systematic review assesses prevalence, outcome, and management of pPCLs in patients undergoing OLT. Read More

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February 2022

Accelerated Pancreatobiliary MRI for Pancreatic Cancer Surveillance in Patients With Pancreatic Cystic Neoplasms.

J Magn Reson Imaging 2022 Apr 7. Epub 2022 Apr 7.

Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Background: Pancreatobiliary MRI is often recommended for patients at risk of developing pancreas cancer. But the surveillance MRI protocol has not yet been widely accepted.

Purpose: To establish an accelerated MRI protocol targeting the table time of 15 minutes for pancreatic cancer surveillance and test its performance in lesion characterization. Read More

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Pancreatic cystic lesions and the role of contrast enhanced endoscopic ultrasound.

Clin Radiol 2022 06 3;77(6):418-427. Epub 2022 Apr 3.

Department of Radiology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 2QQ, UK.

An exponential rise in the use of cross-sectional imaging has led to an increase in the incidental identification of pancreatic cystic lesions (PCL); however, with many subtypes defined to date and heterogeneous morphology with often absent defining radiological features, PCLs present a diagnostic challenge. Computed tomography (CT) and/or magnetic resonance imaging (MRI) alone are frequently not sufficient to provide accurate characterisation. Endoscopic ultrasound (EUS) has an important role in the evaluation and classification of PCLs through its ability to define the internal architecture, which is further enhanced by the use of contrast medium. Read More

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Idiopathic gross dilatation of the pancreatic duct with exocrine insufficiency in a patient with type 1 neurofibromatosis.

SAGE Open Med Case Rep 2022 25;10:2050313X221087570. Epub 2022 Mar 25.

Department of Surgery, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

Pancreatic duct dilatation occurs in conditions including chronic pancreatitis, pancreatic carcinoma and intraductal papillary mucinous neoplasms. Although several pancreatic benign and malignant tumours have been reported in association with type 1 neurofibromatosis, an association with gross pancreatic duct dilatation or ectasia has not been previously published. We report on a patient with type 1 neurofibromatosis found to have idiopathic gross pancreatic duct dilatation and exocrine insufficiency. Read More

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Recent advances in the diagnostic evaluation of pancreatic cystic lesions.

World J Gastroenterol 2022 Feb;28(6):624-634

Division of Gastroenterology, Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.

Pancreatic cystic lesions (PCLs) are becoming more prevalent due to more frequent abdominal imaging and the increasing age of the general population. It has become crucial to identify these PCLs and subsequently risk stratify them to guide management. Given the high morbidity associated with pancreatic surgery, only those PCLs at high risk for malignancy should undergo such treatment. Read More

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February 2022

Case 300: Ruptured Mucinous Cystadenoma of the Pancreas.

Radiology 2022 04;303(1):236-240

From the Departments Radiodiagnosis and Imaging (I.S. C.K., K.S.), Pathology (V.N.), and Gastrosurgery (S.S.V.), Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana Punjab, India 141001.

History Part one of this case appeared 4 months previously and may contain larger images. A 40-year-old woman presented to the outpatient department of our hospital with a 2-year history of abdominal pain, which had worsened in the past few days. There were no other constitutional symptoms; in particular, there was no weight loss or loss of appetite. Read More

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Cystic Neoplasms of the Pancreas: Differential Diagnosis and Radiology Correlation.

Front Oncol 2022 1;12:860740. Epub 2022 Mar 1.

Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.

Although the probability of pancreatic cystic neoplasms (PCNs) being detected is raising year by year, their differential diagnosis and individualized treatment are still a challenge in clinical work. PCNs are tumors containing cystic components with different biological behaviors, and their clinical manifestations, epidemiology, imaging features, and malignant risks are different. Some are benign [e. Read More

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The Role of Interleukin 1 Beta in Differentiating Malignant from Benign Pancreatic Cysts.

J Interferon Cytokine Res 2022 03;42(3):118-126

Department of Endemic Diseases, Faculty of Medicine, Cairo University, Cairo, Egypt.

The frequency of detection of pancreatic cystic lesions (PCLs) in magnetic resonance imaging performed for reasons unrelated to the pancreas reaches up to 13.5%. The aim of this study was to evaluate the role of cyst fluid interleukin 1 beta (IL1β) and different endoscopic ultrasound (EUS) features in differentiating premalignant/malignant from benign pancreatic cysts. Read More

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Mucinous Cystic Neoplasm of Mesentery: A Case Report.

Cureus 2022 Jan 21;14(1):e21482. Epub 2022 Jan 21.

Surgery, Baramati Hospital, Pune, IND.

Mucinous cystic neoplasms are very rare tumours. They may originate from ovaries, pancreas or other intra-abdominal sites but they rarely originate from the mesentery. They can be asymptomatic or present as an abdominal mass or abdominal pain. Read More

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January 2022

A Review of Mucinous Cystic and Intraductal Neoplasms of the Pancreatobiliary Tract.

Arch Pathol Lab Med 2022 03;146(3):298-311

From the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

Context.—: Although most pancreatic and bile duct neoplasms are solid, mucinous cystic neoplasms and intraductal neoplasms have been increasingly recognized even when clinically silent, thanks to the increased use of sensitive imaging techniques. Cystic and intraductal neoplasms of the pancreas are often resectable and curable and constitute about 5% of all pancreatic neoplasms. Read More

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Intrapancreatic accessory spleen with an epidermoid cyst: a malignant mimicry.

BMJ Case Rep 2022 Feb 14;15(2). Epub 2022 Feb 14.

General Surgery, Tan Tock Seng Hospital, Singapore.

With the liberal use of CT scan for clinical diagnosis, clinicians are faced with an increasing number of pancreatic incidentalomas. Compared with other incidentalomas, pancreatic incidentalomas have higher chances of future malignant transformation. There are many differential diagnoses, and epidermoid cyst in an intrapancreatic accessory spleen (ECIPAS) is extremely rare, with only a handful of reports. Read More

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February 2022

Pancreatic intraductal papillary mucinous neoplasms: Current diagnosis and management.

World J Gastrointest Oncol 2021 Dec;13(12):1880-1895

Department of Digestive Tract Surgery, Medical University of Silesia, Katowice 40-752, Poland.

Intraductal papillary mucinous neoplasms (IPMNs) represent approximately 1% of all pancreatic neoplasms and 25% of cystic neoplasms. They are divided into three types: main duct-IPMN (MD-IPPMN), branch duct-IPMN (BD-IPMN), and mixed type-IPMN. In this review, diagnostics, including clinical presentation and radiological investigations, were described. Read More

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December 2021

Pancreatic Serous Cystic Neoplasms and Mucinous Cystic Neoplasms: Differential Diagnosis by Combining Imaging Features and Enhanced CT Texture Analysis.

Front Oncol 2021 23;11:745001. Epub 2021 Dec 23.

Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Objective: To establish a diagnostic model by combining imaging features with enhanced CT texture analysis to differentiate pancreatic serous cystadenomas (SCNs) from pancreatic mucinous cystadenomas (MCNs).

Materials And Methods: Fifty-seven and 43 patients with pathology-confirmed SCNs and MCNs, respectively, from one center were analyzed and divided into a training cohort (n = 72) and an internal validation cohort (n = 28). An external validation cohort (n = 28) from another center was allocated. Read More

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December 2021

[Clinical effect of minimally invasive duodenum preserving pancreatic head resection for benign and pre-malignant lesions of pancreatic head].

Zhonghua Wai Ke Za Zhi 2022 Jan;60(1):39-45

Bengbu Medical College,Bengbu 233030,China.

To examine the clinical effect of minimally invasive duodenum preserving pancreatic head resection(DPPHR) for benign and pre-malignant lesions of pancreatic head. The clinical data of patients with diagnosis of benign or pre-malignant pancreatic head tumor were retrospectively collected and analyzed,all of them underwent laparoscopic or robotic DPPHR between October 2015 and September 2021 at Division of Gastrointestinal and Pancreatic surgery,Zhejiang Provincial People's Hospital. Thirty-three patients were enrolled with 10 males and 23 females. Read More

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January 2022

Pancreatic Lymphangioma: An Unusual Cause of Abdominal Lump.

Cureus 2021 Nov 10;13(11):e19452. Epub 2021 Nov 10.

General Surgery, All India Institute of Medical Sciences, Raipur, IND.

Lymphangiomas are uncommon benign malformations that can occur anywhere in the body. These are hamartomatous malformations with lymphatic differentiation, which uncommonly involve the abdomen and rarely the pancreas. The size of the cysts in pancreatic lymphangioma directly correlates with the clinical manifestations; however, most of them are non-specific. Read More

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November 2021

Pancreatic Cystic Lesions and Malignancy: Assessment, Guidelines, and the Field Defect.

Radiographics 2022 Jan-Feb;42(1):87-105. Epub 2021 Dec 2.

From the Departments of Radiology (F.H.M., C.L.V., H.S.R., C.G.W., H.G., A.A.B., P.N., N.A.H.) and Gastroenterology (R.N.K.), Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N St. Clair Street, Suite 800, Chicago, IL 60611; and Department of Radiology, Medical College of Georgia, Augusta, Ga (P.M.).

The widespread use of high-spatial-resolution cross-sectional imaging has led to an increase in detection of incidental pancreatic cystic lesions. These lesions are a diverse group, ranging from indolent and premalignant lesions to invasive cancers. The diagnosis of several of these lesions can be suggested on the basis of their imaging appearance, while many other lesions require follow-up imaging and/or aspiration. Read More

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Through-the-needle biopsy of pancreatic cystic lesions: current evidence and implications for clinical practice.

Expert Rev Med Devices 2021 Dec 21;18(12):1165-1174. Epub 2021 Dec 21.

Department of Medicine, Gastroenterology and Digestive Endoscopy Unit, The Pancreas Institute, University Hospital of Verona, Verona, Italy.

Introduction: There is increasing evidence to support the efficacy of endoscopic ultrasound (EUS)-guided through-the-needle biopsy (TTNB) technique as a means of sampling pancreatic cystic lesions (PCLs). Results provide evidence demonstrating the benefits of this procedure over standard EUS fine-needle aspiration (FNA), thus supporting a push for its widespread implementation in clinical practice. Though this technique has demonstrated advantages, achieving these advantages in clinical practice is contingent upon careful considerations to ensure safety and efficacy. Read More

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December 2021

Non-inflammatory pancreatic cysts: from diagnosis to treatment (97 cases series).

Rev Col Bras Cir 2021 22;48:e20213009. Epub 2021 Nov 22.

- Universidade Federal do Rio Grande do Norte (UFRN), Unidade de Diagnóstico por Imagem e Métodos Gráficos do Hospital Universitário Onofre Lopes - Natal - RN - Brasil.

Objective: to describe the implications of the diagnosis and treatment of non-inflammatory pancreatic cysts in a series of patients.

Methods: we included patients with pancreatic cysts ≥1.0 cm, excluding those with a presumptive diagnosis of a pseudocyst. Read More

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November 2021

[Pancreatic mucinous cystadenoma complicated by intestinal bleeding].

Z A Kovalenko

Khirurgiia (Mosk) 2021 (11):93-95

Medical and Rehabilitation Center, Moscow, Russia.

Mucinous cystadenoma is a cystic tumor of the pancreas absolutely requiring surgical intervention. The authors report successful surgical treatment of a patient with mucinous pancreatic cystadenoma complicated by severe intestinal bleeding. Read More

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November 2021

Ovarian mass combined with pancreatic neoplasm in pregnancy: A rare case report and literature review.

J Obstet Gynaecol Res 2022 Jan 2;48(1):244-250. Epub 2021 Nov 2.

Department of Obstetrics and Gynecology, Kyung Hee Medical Center, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.

A 35-year-old woman presented with abdominal discomfort at 26 weeks gestation. The magnetic resonance imaging demonstrated a huge unilocular cystic mass with mural nodules originated from body and tail of pancreas. There was also a cystic mass in the left ovary with suppressed intensity on fat saturated image. Read More

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January 2022

A case of ectopic pancreas of the stomach accompanied by intraductal papillary mucinous neoplasm with GNAS mutation.

World J Surg Oncol 2021 Oct 21;19(1):309. Epub 2021 Oct 21.

Department of Surgical Pathology, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya, Hyogo, 663-8501, Japan.

Background: Ectopic pancreas is basically a benign disease and is not always necessary to be removed. However, all types of neoplasms occurring in the normal pancreas such as ductal adenocarcinomas and intraductal papillary mucinous neoplasms (IPMNs) may develop even within ectopic pancreas. We recently encountered an extremely rare case of ectopic pancreas in the gastric antrum associated with IPMN possessing a GNAS mutation. Read More

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October 2021

Xanthogranulomatous Pancreatitis Accompanied by Xanthogranulomatous Cholecystitis: A Case Report and Literature Review.

Pancreas 2021 08;50(7):1037-1041

From the Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.

Abstract: Xanthogranulomatous pancreatitis (XGP) is extremely rare, with only 31 cases reported in the English literature to date. We reviewed previously reported 17 articles about XGP and report an additional case of XGP. This is the first case of XGP with xanthogranulomatous cholecystitis accompanied by intraductal papillary mucinous carcinoma (IPMC) in an 80-year-old woman. Read More

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CT classification model of pancreatic serous cystic neoplasms and mucinous cystic neoplasms based on a deep neural network.

Abdom Radiol (NY) 2022 01 12;47(1):232-241. Epub 2021 Oct 12.

Department of Radiology, The First Affiliated Hospital, Zhejiang University School of Medicine, #79 Qingchun Road, Hangzhou, 310003, Zhejiang Province, P.R. China.

Background: At present, numerous challenges exist in the diagnosis of pancreatic SCNs and MCNs. After the emergence of artificial intelligence (AI), many radiomics research methods have been applied to the identification of pancreatic SCNs and MCNs.

Purpose: A deep neural network (DNN) model termed Multi-channel-Multiclassifier-Random Forest-ResNet (MMRF-ResNet) was constructed to provide an objective CT imaging basis for differential diagnosis between pancreatic serous cystic neoplasms (SCNs) and mucinous cystic neoplasms (MCNs). Read More

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January 2022

Should non-invasive diffuse main-duct intraductal papillary mucinous neoplasms be treated with total pancreatectomy?

HPB (Oxford) 2022 05 23;24(5):645-653. Epub 2021 Sep 23.

Johns Hopkins Medical Institutions and the Pancreatic Cancer Precision Medicine Center of Excellence Program, Baltimore, MD, USA. Electronic address:

Background: Main-duct (MD) intraductal papillary mucinous neoplasm (IPMN) is associated with malignancy risk. There is a lack of consensus on treatment (partial or total pancreatectomy) when the MD is diffusely involved. We sought to characterize the pancreatic remnant fate after partial pancreatectomy for non-invasive diffuse MD-IPMN. Read More

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Sometimes You Have to Judge a Book by Its Cover: The Case of a Masquerading Pancreatic Mucinous Cyst.

ACG Case Rep J 2021 Apr 27;8(4):e00554. Epub 2021 Apr 27.

Division of Gastroenterology and Hepatology, Department of Medicine, Strong Memorial Hospital, University of Rochester Medical Center, Rochester, NY.

Pancreatic cystic lesions are difficult to evaluate amid acute pancreatitis. Without previous pancreatic imaging, it is challenging to discern between pancreatic acute fluid collections and cystic neoplasms. We present a 29-year-old woman with acute pancreatitis and initial cross-sectional imaging suggesting a 2. Read More

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Pancreatic Cysts after Endoscopic Ultrasonography-Guided Ethanol and/or Paclitaxel Ablation Therapy: Another Mimic of Pancreatic Pseudocysts.

Pathobiology 2022 26;89(1):49-55. Epub 2021 Aug 26.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: Endoscopic ultrasound-guided ablation (EUS-A) therapy is a minimally invasive procedure for pancreatic-cystic tumors in patients with preoperative comorbidities or in patients who are not indicated for surgical resection. However, histopathologic characteristics of pancreatic cysts after ablation have not been well-elucidated.

Methods: Here, we analyzed pathological findings of 12 surgically resected pancreatic cysts after EUS-A with ethanol and/or paclitaxel injection. Read More

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January 2022

Mucinous cystic neoplasm of the pancreas misdiagnosed as pancreatic pseudocyst: A case report.

Asian J Surg 2021 Dec 6;44(12):1602-1603. Epub 2021 Sep 6.

First Hospital of Lanzhou University, Lanzhou Gansu, 730000, China. Electronic address:

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December 2021

[Intraductal neoplasms of the pancreas].

Pathologe 2021 Sep 17;42(5):472-483. Epub 2021 Aug 17.

Institut für Pathologie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Deutschland.

The latest WHO classification of tumors of the digestive system (2019) has introduced new concepts for the stratification of intraductal neoplasms of the pancreas, mostly based on molecular genetics and malignant potential. Among them, pancreatic intraepithelial neoplasias (PanINs) and intraductal papillary mucinous neoplasms (IPMN) are both precursors of pancreatic ductal adenocarcinoma, whereas intraductal oncocytic papillary neoplasms (IOPN) and intraductal tubulopapillary neoplasms (ITPN) are usually associated with less aggressive subtypes of pancreatic cancer and therefore have a much better prognosis. Hence, it is of utmost importance to correctly classify these lesions and to distinguish them from each other as well as from other nonductal types of neoplasms, which can rarely display an intraductal growth, such as neuroendocrine tumors and acinar cell carcinomas. Read More

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September 2021