756 results match your criteria Imaging in Hypertrophic Osteoarthropathy

Hypertrophic Osteoarthropathy: A Secondary Manifestation of Malignant Melanoma.

Case Rep Rheumatol 2021 18;2021:6691320. Epub 2021 Jan 18.

HonorHealth Internal Medicine Residency, Scottsdale, AZ, USA.

Background: Hypertrophic osteoarthropathy (HOA) is a rare finding in the setting of metastatic melanoma. A majority of cases of secondary HOA involve lung malignancies. Evaluation of presenting symptoms such as polyarthralgia and clubbing followed by review of imaging studies are diagnostic steps for HOA. Read More

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January 2021

Atypical and incomplete pulmonary hypertrophic osteoarthropathy in the left distal femur: a case report.

BMC Surg 2020 Nov 23;20(1):293. Epub 2020 Nov 23.

Department of Orthopaedic Surgery, Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Background: Pulmonary hypertrophic osteoarthropathy (PHO) is a rare paraneoplastic syndrome that mainly occurs in patients with lung cancer. Most symptoms occur symmetrically, and unilateral symptoms without clubbing are infrequent. This report presents the case of a rare atypical symptom that was highly suspected of being PHO. Read More

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November 2020

Primary pulmonary lymphoepithelioma-like carcinoma accompanied by hypertrophic pulmonary osteoarthropathy in a non-epidemic region: a case report and literature review.

J Int Med Res 2020 Nov;48(11):300060520965816

Department of Respiratory and Critical Care Medicine, Ningbo First Hospital, Ningbo, China.

Pulmonary lymphatic epithelioma-like carcinoma (LELC) is a rare and unique subtype, accounting for 0.9% of all lung cancers. To date, just over 200 cases have been reported worldwide. Read More

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November 2020

Bone Scintigraphy in Pembrolizumab-Induced Inflammatory Arthritis.

Clin Nucl Med 2020 Dec;45(12):999-1000

From the Department of Radiology, Toranomon Hospital, Tokyo, Japan.

We present a novel report on the use of bone scintigraphy in pembrolizumab-induced inflammatory arthritis. A 70-year-old man with lung cancer complained about arthralgia after 7 courses of the pembrolizumab therapy. Tc-HMDP bone scintigraphy revealed symmetrically strong uptakes in the major distal joints of the upper and lower extremities, thereby clearly identifying them as the affected joints. Read More

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December 2020

Sudden onset polyarthritis as a paraneoplastic syndrome from non-small cell lung cancer.

J Community Hosp Intern Med Perspect 2020 May 21;10(2):174-178. Epub 2020 May 21.

Methodist Dallas Medical Center, Dallas, TX, USA.

A 48-year-old male presented to the emergency room for 2 weeks of joint pain and swelling of his four extremities. His symptoms started suddenly and were quite debilitating. His hands, fingers, knees, and ankles were so swollen and painful that he was unable to get out of bed and had to use crutches to ambulate. Read More

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Hypertrophic Pulmonary Osteoarthropathy Revealing a Solitary Fibrous Tumor.

Mayo Clin Proc 2020 08;95(8):1567-1568

Department of Clinical Immunology & Infectious Diseases, Centre Hospitalier de Vienne Lucien Hussel, Médecine interne, Montée du Dr Chapuis, Vienne, Rhône-Alpes, France. Electronic address:

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Secondary Hypertrophic Osteoarthropathy in Pediatric Hodgkin lymphoma.

Arthritis Rheumatol 2020 11 10;72(11):1891. Epub 2020 Sep 10.

The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

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November 2020

Unilateral Hippocratic Fingers and Macaroni Sign.

Arthritis Rheumatol 2020 09 13;72(9):1570. Epub 2020 Jul 13.

Dr. von Hauner Children's Hospital Hospital of the Ludwig-Maximilians-University, Munich, Germany.

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September 2020

Incomplete primary hypertrophic osteoarthropathy.

BMJ Case Rep 2020 May 13;13(5). Epub 2020 May 13.

Department of Orthopaedics, University College of Medical Sciences, New Delhi, Delhi, India.

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Rheumatoid Arthritis-Associated Interstitial Lung Disease.

Am J Med Sci 2020 05 26;359(5):312-313. Epub 2019 Dec 26.

Internal Medicine, University of Texas Health Science Center at Houston; Houston, Texas.

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Cardiac imaging in a patient with differential clubbing.

Kardiol Pol 2020 05 21;78(5):465-466. Epub 2020 Feb 21.

Faculty of Medicine, Vilnius University, Vilnius, Lithuania; Centre of Cardiology and Angiology, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania; Centre of Cardiothoracic Surgery, Vilnius University Hospital Santaros Klinikos, Vilnius,Lithuania

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A 49-Year-Old Man With Cough and Hand, Wrist, and Knee Pain.

Chest 2020 02;157(2):e47-e51

Department of Pulmonary and Critical Care, Drexel University College of Medicine, Philadelphia, PA. Electronic address:

Case Presentation: A 49-year-old man was sent by his primary care physician to the rheumatology clinic with complaints of several months of bilateral lower extremity swelling. The swelling migrated from both ankles up to his knees. Presenting symptoms consisted of bilateral knee pain as well as bilateral wrist and hand pain with swelling. Read More

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February 2020

Touraine-Solente-Gole syndrome.

BMJ Case Rep 2019 Nov 19;12(11). Epub 2019 Nov 19.

Department of Medicine, All India Institute of Medical Sciences, New Delhi, India

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November 2019

Schamroth sign.

Naoki Matsuura

CMAJ 2019 Nov;191(45):E1251

Department of Internal Medicine, Koga General Hospital, Miyazaki, Japan

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November 2019

Hypertrophic Osteoarthropathy in a Patient With Primary Hepatic Angiosarcoma.

Clin Nucl Med 2020 Jan;45(1):57-59

Department of Nuclear Medicine, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.

Primary hepatic angiosarcoma was diagnosed in a 59-year-old woman who presented an arthralgia of limbs and dry cough for 6 weeks. Physical examination revealed digital clubbing. A Tc-MDP bone scintigraphy showed diffusely increased uptake along the cortical margins of long bones, suggesting hypertrophic osteoarthropathy. Read More

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January 2020

A case of primary hypertrophic osteoarthropathy: Management considerations.

Int J Rheum Dis 2019 Nov 24;22(11):2080-2081. Epub 2019 Oct 24.

Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

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November 2019

Impaired bone microarchitecture in distal interphalangeal joints in patients with primary hypertrophic osteoarthropathy assessed by high-resolution peripheral quantitative computed tomography.

Osteoporos Int 2020 Jan 23;31(1):153-164. Epub 2019 Oct 23.

Musculoskeletal Research Laboratory and Bone Quality and Health Assessment Centre, Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, 5/F Lui Che Woo Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong, SAR, Hong Kong.

This study aimed to investigate the bone impairment in finger joints in PHO patients by HR-pQCT. Results showed distinguished differences in bone architecture and biomechanics parameters at DIPs between PHO patients and healthy controls using HR-pQCT assessment. Besides, serum PGE2, hsCRP and ESR levels were found negatively correlated with total vBMD. Read More

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January 2020

Finger clubbing and cirrhosis in a sarcoidosis patient.

Monaldi Arch Chest Dis 2019 Oct 18;89(3). Epub 2019 Oct 18.

Department of Internal Medicine Medicine, Cerrahpasa Medical Faculty, Istanbul Cerrahpasa University.

Sarcoidosis is a multisystem granulomatous inflammatory disorder frequently affecting the lungs, but also the liver, along with cirrhosis and portal hypertension occurring in less than 1% of the patients. A 56-year-old female presented with dyspnea, abdominal and leg swelling. Physical examination revealed finger clubbing, ascites and pretibial edema. Read More

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October 2019

Characteristic Facial Appearance Was the Key to Diagnosing Chronic Enteropathy Associated with SLCO2A1-associated Primary Hypertrophic Osteoarthropathy.

Intern Med 2020 Feb 15;59(4):491-494. Epub 2019 Oct 15.

Department of Gastroenterology, Oita University, Japan.

Patients with chronic enteropathy associated with SLCO2A1 (CEAS) develop multiple circular, longitudinal, or eccentric ulcers in the ileum. It is sometimes difficult to distinguish CEAS from Crohn's disease. CEAS and primary hypertrophic osteoarthropathy (PHO) are together known to be caused by a mutation of SLCO2A1 gene. Read More

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February 2020

Dyspnoea, clubbing, cirrhosis, and bubbles in both sides of the heart suggests hepatopulmonary syndrome.

Lancet 2019 Aug 8;394(10197):510. Epub 2019 Aug 8.

Liver Transplant Unit, Austin Hospital, Heidelberg, VIC, Australia.

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Reversible Hippocratic Fingers in a Patient with Pneumonia.

Am J Med 2020 01 24;133(1):e9-e10. Epub 2019 Jul 24.

Division of Internal Medicine, University Hospital Basel.

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January 2020

Hypertrophic Osteoarthropathy in Cystic Fibrosis.

Arthritis Rheumatol 2019 10 27;71(10):1633. Epub 2019 Aug 27.

Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK.

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October 2019

A young man with progressive worsening dyspnoea

Aust J Gen Pract 2018 12;47(12):856-858

MBBS, FRACP, PhD, Staff Specialist – Respiratory Medicine, Department of Respiratory Medicine, Gold Coast University Hospital, Southport, Qld; Associate Professor, School of Medicine, Griffith University, Southport, Qld

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December 2018

Primary Hypertrophic Osteoarthropathy Mimicking Juvenile Idiopathic Arthritis: A Novel SLCO2A1 Mutation and Imaging Findings.

Cytogenet Genome Res 2019 15;158(3):126-132. Epub 2019 Jun 15.

Primary hypertrophic osteoarthropathy (PHO), also known as pachydermoperiostosis, is a rare, multisystemic, autosomal recessive condition typically presenting with digital clubbing, osteoarthropathy, and various skin manifestations. Radiographs show distinctive periosteal reaction and thickening along the long bones. PHO is caused by homozygous mutations in the HPGD gene in chromosome 4q34. Read More

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September 2019

Feet Deformity and Gait Disturbance in a Patient with Pachydermoperiostosis (PDP). Case Study.

Ortop Traumatol Rehabil 2019 Apr;21(2):123-129

Klinika Ortopedii i Ortopedii Dziecięcej, Uniwersytet Medyczny w Łodzi, Polska / Orthopedics and Pediatric Orthopedics Department, Medical University of Łódź, Poland.

Pachydermoperiostosis is a rare condition representing a primary form of hypertrophic osteoarthropathy. It presents in different stages. Patients often overlook early symptoms, because they are benign. Read More

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Hypertrophic osteoarthropathy in an adult macaque.

Int J Paleopathol 2019 06 28;25:39-45. Epub 2019 Apr 28.

Institute of Archaeology, University College London, 31-34 Gordon Square, London, WC1H 0PY, United Kingdom.

Objective: To evaluate through differential diagnosis whether hypertrophic osteoarthropathy was present on an adult macaque skeleton.

Materials: Skeletal remains of a well-preserved adult macaque (Macaca) of unknown species curated by the archaeology department at University College London.

Methods: Macroscopic and radiographic evaluation of pathological lesions. Read More

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Exogenous lipoid pneumonia in children: A systematic review.

Paediatr Respir Rev 2020 Feb 20;33:45-51. Epub 2019 Jan 20.

Division of Paediatric Pulmonology, Department of Paediatrics and Child Health and Medical Research Council Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.

Objectives: To describe the clinical-radiological-pathological characteristics and treatment outcomes of children with suspected exogenous lipoid pneumonia (ELP).

Design: Systematic review. We searched electronic databases and reference lists published between 1967 and 2018, restricted to non-accidental cases. Read More

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February 2020

Using synovial volume measurement by MRI to evaluate the effect of 32P Radiation synovectomy on hemophilic arthropathy patients.

J Xray Sci Technol 2019 ;27(2):187-195

Department of Radiology, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou, Henan, China.

Objective: To evaluate the potential of synovial membrane volume measurement by MRI in monitoring the effect of radiation synovectomy on patients of Hemophilic Arthropathy (HA).

Methods: We studied 63 diseased joints of 42 HA patients who received hospitalized services at the Hemophilia Diagnosis and Treatment Center of Henan Provincial People's Hospital from May 2011 to January 2015. Unenhanced and enhanced MR scanning of each diseased joint was performed simultaneously. Read More

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Review of paraneoplastic syndromes in children.

Pediatr Radiol 2019 04 16;49(4):534-550. Epub 2019 Mar 16.

Department of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02215, USA.

Paraneoplastic syndromes are defined as clinical syndromes that are not related to direct tumor invasion or compression but are secondary to tumor secretion of functional peptides/hormones or related to immune cross-reactivity with normal host tissue. Paraneoplastic syndromes have a wide range of presentations and can present before the primary malignancy or tumor recurrence is diagnosed. They can mimic non-neoplastic processes, making detection, diagnosis and treatment difficult. Read More

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Hypoxia due to intrapulmonary vascular dilatation in a toddler with a congenital portacaval shunt: case report.

BMC Pulm Med 2019 Feb 22;19(1):49. Epub 2019 Feb 22.

College of Medicine and Health Sciences - UAE University, Alain City, United Arab Emirates.

Background: The term hepatopulmonary syndrome typically applies to cyanosis that results from "intrapulmonary vascular dilatation" due to advanced liver disease. Similar findings may result from a congenital portosystemic shunt without liver disease. An adverse consequence of such shunts is intrapulmonary vascular dilatation, which affects the microvascular gas exchange units for oxygen. Read More

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February 2019