732 results match your criteria Imaging in Ganglioglioma


A rare case of oligodendroglioma with gangliocytic differentiation in a 31-year-old male: importance of genetic testing for IDH1/2.

Brain Tumor Pathol 2020 Jul 5;37(3):95-99. Epub 2020 Jun 5.

Department of Pathology, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.

We report a rare case of oligodendroglioma with gangliocytic differentiation. A 31-year-old male without a past medical history was admitted with a sudden seizure. On magnetic resonance imaging, an approximately 7-cm mass with necrosis was noted in the right frontal lobe. Read More

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http://dx.doi.org/10.1007/s10014-020-00368-wDOI Listing

Diffuse midline glioma of the cervical spinal cord with H3 K27M genotype phenotypically mimicking anaplastic ganglioglioma: a case report and review of the literature.

Brain Tumor Pathol 2020 Jul 25;37(3):89-94. Epub 2020 May 25.

Institute of Pathology, University Hospital Salzburg, Paracelsus Medical University, Müllner Hauptstraße 48, 5020, Salzburg, Austria.

Here, we report on a 28-year old male patient presenting with neck and shoulder pain, dysesthesia of all four limbs and hypesthesia of both hands, without motor deficits. Magnetic resonance imaging showed an intradural, intramedullary mass of the cervical spinal cord of 6.4 cm length and 1. Read More

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http://dx.doi.org/10.1007/s10014-020-00365-zDOI Listing

Imaging of Neuronal and Mixed Glioneuronal Tumors.

J Comput Assist Tomogr 2020 May/Jun;44(3):356-369

Department of Radiology. Alexandria Faculty of Medicine, Alexandria, Egypt.

Neuronal and mixed glioneuronal tumors represent a group of neoplasms with varying degrees of neural and glial elements. Their age of presentation varies, but they are most commonly seen in children and young adults. With the exception of anaplastic ganglioglioma and other atypical variants, most lesions are low grade; however, they can have significant morbidity because of seizures, mass effect, or difficult to treat hydrocephalus. Read More

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http://dx.doi.org/10.1097/RCT.0000000000001010DOI Listing
May 2020
1.602 Impact Factor

Risk stratification in pediatric low-grade glioma and glioneuronal tumor treated with radiation therapy: An integrated clinicopathologic and molecular analysis.

Neuro Oncol 2020 Feb 13. Epub 2020 Feb 13.

Department of Pathology, St. Jude Children's Research Hospital.

Background: Management of unresectable pediatric low-grade glioma and glioneuronal tumor (LGG/LGGNT) is controversial. There are no validated prognostic features to guide use of radiation therapy (RT). Our study aimed to identify negative prognostic features in patients treated with RT using clinicopathologic and molecular data and validate these findings in an external dataset. Read More

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http://dx.doi.org/10.1093/neuonc/noaa031DOI Listing
February 2020
5.562 Impact Factor

A Multi-Institutional Analysis of Factors Influencing Surgical Outcomes for Patients with Newly Diagnosed Grade I Gliomas.

World Neurosurg 2020 Mar 31;135:e754-e764. Epub 2019 Dec 31.

Department of Neurological Surgery, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

Objective: To assess the impact of intraoperative magnetic resonance imaging (iMRI), extent of resection (EOR), and other factors on overall survival (OS) and progression-free survival (PFS) for patients with newly diagnosed grade I gliomas.

Methods: A multicenter database was queried to identify patients with grade I gliomas. Retrospective analyses assessed the impact of patient, treatment, and tumor characteristics on OS and PFS. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.12.156DOI Listing

Multifocal Intracranial Ganglioglioma in a Sexagenarian: Case Report and Review of the Current Literature.

World Neurosurg 2020 Jun 24;138:498-503. Epub 2019 Dec 24.

Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.

Background: Gangliogliomas are rare, well-differentiated, low-grade neoplasms that most often occur unifocally in children and most commonly affect the temporal lobe. Gangliogliomas that occur in patients age >40 years tend to have worse prognoses. These tumors generally stain positively for neural and glial cell markers, as well as CD34. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.12.084DOI Listing

Awake Craniotomy for a Left Pan-Hippocampal Diffuse Low-Grade Glioma in a Deaf and Mute Patient Using Sign Language.

World Neurosurg 2020 Feb 29;134:629-634.e1. Epub 2019 Nov 29.

Department of Neurosurgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; PhD Program in Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan. Electronic address:

Background: Awake craniotomy is becoming an essential technique, especially for intrinsic brain tumors which have no clear margins and where extent of resection (EOR) matters. However, intraoperative monitoring for awaken patients requires voice feedback in regular settings. Resection of hippocampal glioma is challenging because of its deep-seated location, its extension in an anterior-posterior axis, and being covered with eloquent cortex. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.11.129DOI Listing
February 2020

Correction to: Efficacy of Dabrafenib for three children with brainstem BRAF positive ganglioglioma.

J Neurooncol 2019 Dec;145(3):595

Department of Pediatrics, Centre Mère-enfant Soleil du CHU de Québec-Université Laval, Québec, Canada.

In the original article, the author names were published incorrectly. The names are correct in this publication. Read More

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http://dx.doi.org/10.1007/s11060-019-03350-5DOI Listing
December 2019

Role of diffusion weighted imaging for differentiating cerebral pilocytic astrocytoma and ganglioglioma BRAF V600E-mutant from wild type.

Neuroradiology 2020 Jan 30;62(1):71-80. Epub 2019 Oct 30.

Neuroradiology Unit, IRCCS Istituto Giannina Gaslini, via G. Gaslini 5, I-16147, Genova, Italy.

Purpose: BRAF V600E mutation is a distinctive genomic alteration of pediatric low-grade gliomas with prognostic and therapeutic implications. The aim of this retrospective multicenter study was to analyze imaging features of BRAF V600E-mutant and wild-type cerebral pilocytic astrocytomas (PAs) and gangliogliomas (GGs), focusing on the role of diffusion weighted imaging (DWI).

Methods: We retrospectively evaluated 56 pediatric patients with histologically proven, treatment-naïve PAs and GGs who underwent conventional MRI, DWI, and molecular analysis for BRAF V600E mutation. Read More

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http://dx.doi.org/10.1007/s00234-019-02304-yDOI Listing
January 2020

Mixed Solid and Cystic Mass in an Infant.

AJNR Am J Neuroradiol 2019 11 3;40(11):1792-1795. Epub 2019 Oct 3.

From the Departments of Radiology (J.C.B., J.B.G., D.K.K., L.E., P.M.).

Desmoplastic infantile tumors are rare supratentorial brain tumors that occur in pediatric patients. Desmoplastic infantile tumors are made up of 2 subtypes: desmoplastic infantile gangliogliomas and desmoplastic infantile astrocytomas. Desmoplastic infantile tumors are often identifiable on imaging on the basis of multiple characteristics. Read More

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http://dx.doi.org/10.3174/ajnr.A6226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975114PMC
November 2019

A Dandy-Walker malformation associated with ganglioglioma.

Chin Med J (Engl) 2019 Oct;132(20):2495-2497

Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

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http://dx.doi.org/10.1097/CM9.0000000000000457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831061PMC
October 2019
1 Read

Desmoplastic Infantile Ganglioglioma Masquerading as an Arachnoid Cyst.

Oman Med J 2019 Sep;34(5):464-468

Dental School, Boston University, Massachusetts, USA.

Desmoplastic infantile ganglioglioma (DIG) is a rare supratentorial brain tumor, which is usually diagnosed before the age of two and has a favorable prognosis. To date, only a few cases have been reported in the literature. We report a case of DIG in a three-month-old boy who presented to our pediatric emergency department with decreased activity and excessive crying. Read More

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http://dx.doi.org/10.5001/omj.2019.84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745420PMC
September 2019
1 Read

Polymorphous Low-Grade Neuroepithelial Tumor of the Young: A Case Report with Genomic Findings.

World Neurosurg 2019 Dec 11;132:347-355. Epub 2019 Sep 11.

Department of Pathology, Medical College of Georgia at Augusta University, Augusta, Georgia, USA. Electronic address:

Background: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently recognized epileptogenic neuroepithelial tumor. Despite its distinctiveness, its polymorphous histology and the nature of its oligodendrocyte-like cells remain unclear.

Case Description: A 30-year-old, right-handed man was diagnosed with intractable epilepsy since 22 years of age. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.08.221DOI Listing
December 2019
17 Reads
2.417 Impact Factor

Symptomatic Diffuse Vasospasm After Resection of Temporal Ganglioglioma: Review of the Literature with Case Illustration.

World Neurosurg 2019 Dec 7;132:230-235. Epub 2019 Sep 7.

Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

Background: Symptomatic cerebral vasospasm may occur in the setting of aneurysmal subarachnoid hemorrhage, traumatic brain injury, or after anterior skull base surgery, but its occurrence is extremely rare in the background of glioma surgical resection.

Case Description: We present a rare case of symptomatic diffuse vasospasm, which is the fourth reported case of symptomatic vasospasm after temporal lobectomy and the third in the setting of a glial tumor. This patient, a 10-year-old boy, developed bilateral, progressive cerebral infarcts because of diffuse vasospasm after anteromesial temporal lobectomy for a left temporal ganglioglioma leading to significant morbidity. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.08.239DOI Listing
December 2019
3 Reads

Efficacy of Dabrafenib for three children with brainstem BRAF positive ganglioglioma.

J Neurooncol 2019 Oct 9;145(1):135-141. Epub 2019 Sep 9.

Department of Pediatrics, Centre Mère-enfant Soleil du CHU de Québec-Université Laval, Québec, Canada.

Purpose: Children with unresectable brainstem-infiltrated ganglioglioma have poor progression-free survival when treated with conventional chemotherapy and radiation regimens. The BRAF mutation occurs in a large number of gangliogliomas, making them amenable for targeted therapy using mutation-specific kinase inhibitors. However, limited data exists on the effectiveness and best treatment duration of these inhibitors in this tumor setting. Read More

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http://link.springer.com/10.1007/s11060-019-03280-2
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http://dx.doi.org/10.1007/s11060-019-03280-2DOI Listing
October 2019
1 Read

[Rosette-forming glioneuronal tumor in vermis: report of a case].

Authors:
W Y Zhang B C Wang

Zhonghua Bing Li Xue Za Zhi 2019 09;48(9):718-720

Department of Pathology, Zhongnan Hospital of Wuhan University; Wuhan University Center for Pathology and Molecular Diagnostics; Department of Pathology, Wuhan University School of Medicine; Wuhan 430000, China.

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2019.09.011DOI Listing
September 2019
1 Read

Sellar/Suprasellar Ganglioglioma: Clinical Image.

World Neurosurg 2019 Dec 20;132:1-3. Epub 2019 Aug 20.

Department of Neurosurgery, University Neuroscience Augusta Back, Augusta, Georgia, USA.

Background: This report presents a rare presentation of a ganglioglioma in the sellar/suprasellar region. On the basis of the patient's presentation and imaging characteristics, the initial diagnosis was craniopharyngioma. While gangliogliomas are already rare brain tumors that are usually found in the frontal and temporal lobes of young patients, the presentation of this tumor in the sellar region is exceedingly rare. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.08.057DOI Listing
December 2019
2 Reads

Freiburg Neuropathology Case Conference : Hypersalivatory Seizures in a 6-year-old Child.

Clin Neuroradiol 2019 Sep;29(3):581-586

Department of Neuropathology, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://link.springer.com/10.1007/s00062-019-00820-1
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http://dx.doi.org/10.1007/s00062-019-00820-1DOI Listing
September 2019
1 Read

Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas.

J Neuropathol Exp Neurol 2019 09;78(9):780-787

Department of Neurosurgery, Emory University, Atlanta, Georgia.

Infratentorial glioneuronal neoplasms are overall quite rare and are more commonly low-grade with surgical excision usually being curative. Multiple distinct histologic entities have been described including rosette-forming glioneuronal tumor, papillary glioneuronal tumor, neurocytoma, dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease), cerebellar liponeurocytoma, and ganglioglioma. While each of these entities has distinct findings, in some instances a tumor may demonstrate overlapping histologic features with mixed components. Read More

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http://dx.doi.org/10.1093/jnen/nlz060DOI Listing
September 2019
2 Reads

Bevacizumab in treating the cystic components of pediatric low-grade gliomas: A report of four patients.

Pediatr Blood Cancer 2019 11 26;66(11):e27917. Epub 2019 Jul 26.

The University of Rochester School of Medicine and Dentistry, Rochester, New York.

Low-grade gliomas (LGG) are among the most common types of brain tumors in children and young adults. These tumors often consist of solid and cystic components. Bevacizumab is a documented treatment for progressive LGG, yet the impact of therapy on the cystic component of these tumors is unknown. Read More

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http://dx.doi.org/10.1002/pbc.27917DOI Listing
November 2019
4 Reads

Diverse Behavior in 18F-Fluorocholine PET/CT of Brain Tumors in Patients With Neurofibromatosis Type 1.

Clin Nucl Med 2019 Aug;44(8):e472-e476

From the Nuclear Medicine.

Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that causes CNS tumors in around 20% of patients, being pilocytic astrocytomas (PA), and particularly optic pathway gliomas (OPG), the most common. We present three cases of NF1 patients referred for F-fluorocholine PET/CT because of suspected glioma in the setting of ongoing FUMEGA (Functional and Metabolic Glioma Analysis) trial. One case turned out to be a WHO grade I ganglioglioma; the second was a high grade glioma; and the last one (negative in PET) a probable low-grade glioma. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002636DOI Listing
August 2019
3 Reads

Desmoplastic infantile ganglioglioma.

Pan Afr Med J 2019 11;32:113. Epub 2019 Mar 11.

Department of Pathology, Rabta Hospital, Faculty of Medicine of Tunis, University of Tunis el Manar, Tunisia.

The term desmoplastic infantile ganglioglioma was coined by VandenBerg et al in 1987. In their first report these authors referred to a rare, distinct brain tumor. About 60 cases of desmoplastic infantile ganglioglioma have been described in the literature since its first description. Read More

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http://dx.doi.org/10.11604/pamj.2019.32.113.12669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560944PMC
July 2019
14 Reads

Spinal Intramedullary Ganglioglioma in Children: An Unusual Location of a Common Pediatric Tumor.

Pediatr Neurosurg 2019 18;54(4):245-252. Epub 2019 Jun 18.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India,

Ganglioglioma is a common CNS tumor in children, mostly found in the temporal lobe, causing epilepsy. Spinal gangliogliomas are very rare, accounting for 1.1% of all intramedullary spinal tumors. Read More

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http://dx.doi.org/10.1159/000500427DOI Listing
January 2020
5 Reads
0.497 Impact Factor

Clinical relevance of BRAF status in glial and glioneuronal tumors: A systematic review.

J Clin Neurosci 2019 Aug 27;66:196-201. Epub 2019 May 27.

Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami-Koshigaya, Koshigaya-shi, Saitama 343-8555, Japan. Electronic address:

Alterations in the BRAF gene have been reported to play a key role in the tumorigenesis of various tumors. Recent studies have shown the existence of BRAF alterations in ganglioglioma (GG), pilocytic astrocytoma (PA), pleomorphic xanthoastrocytomas (PXA), and epithelioid glioblastoma (eGBM). The focus of this review was the association between the clinical characteristics and BRAF status in these glial and glioneuronal tumors. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.05.014DOI Listing
August 2019
5 Reads

Lumbar Ganglioneuroma from the Paravertebral Body Presenting in Continuity Between Intradural and Extradural Spaces.

World Neurosurg 2019 Aug 15;128:289-294. Epub 2019 May 15.

Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan.

Background: Ganglioneuroma is a well-differentiated benign tumor that develops from the ganglion cells of the posterior mediastinum, retroperitoneum, cervical spine, and adrenal glands. The paravertebral body, in which the sympathetic trunk exists, is a common tumor site, and tumor sometimes invades the spinal canal through the intervertebral foramen. There have been no reports regarding tumors with intradural and extradural continuity. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.05.065DOI Listing
August 2019
4 Reads

Comparison of conventional, diffusion, and perfusion MRI between infratentorial ganglioglioma and pilocytic astrocytoma.

Acta Radiol 2019 Dec 29;60(12):1687-1694. Epub 2019 Apr 29.

Department of Radiology, Huashan Hospital, Fudan University, Shanghai, PR China.

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http://dx.doi.org/10.1177/0284185119845088DOI Listing
December 2019
12 Reads

Composite pleomorphic xanthoastrocytoma-ganglioglioma; assessing and addressing the dilemma of differential expression of neuronal markers: Case report with diagnostic perspective.

Indian J Pathol Microbiol 2019 Apr-Jun;62(2):296-299

Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar East, Gautam Nagar, New Delhi, India.

We report the case of a 5-year-old male child presenting with seizures for 4 months. Magnetic resonance imaging (MRI) revealed a cortical-based solid cystic lesion in the right parietal lobe. Histopathological examination showed a tumour comprised of spindled glial fibrillary acid protein (GFAP) positive neoplastic cells interspersed with bizarre pleomorphic cells showing nuclear pseudoinclusions and intermingled dysplastic ganglion cells variably immunopositive for synaptophysin, chromogranin, Neu-N and immunonegative for neuron filament protein (NFP). Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_458_18DOI Listing
August 2019
6 Reads

Ganglioglioma with Cerebrospinal Fluid Rhinorrhea: A Rare Presentation.

World Neurosurg 2019 Jul 25;127:11-14. Epub 2019 Mar 25.

Department of Neurosurgery, National Institute of Mental Health and Neuro Sciences, Bangalore, India.

Background: Gangliogliomas are low-grade gliomas, and patients generally present with seizures. Gangliogliomas commonly occur in the temporal lobe and predominantly occur in children. Malignant progression is rare. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.156DOI Listing
July 2019
4 Reads

Intramedullary Spinal Cord Ganglioglioma Presenting as Hyperhidrosis: A Rare Case Report and Literature Review.

World Neurosurg 2019 Jul 20;127:232-236. Epub 2019 Mar 20.

Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. Electronic address:

Background: Hyperhidrosis is caused by sympathetic dysfunction of the central or peripheral nervous system. However, intramedullary spinal cord tumors presenting with hyperhidrosis as an initial symptom have been rarely reported in the literature.

Case Description: This case involves an 18-year-old man who presented with abnormal enhanced sweating and flushing on the bilateral side of his face and neck that had persisted for 6 years. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.115DOI Listing
July 2019
12 Reads

Ictal FDGPET and SPECT in hemifacial seizures due to cerebellar epilepsy-Case report.

Neurol India 2019 Jan-Feb;67(1):169-172

Department of Neurosurgery, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India.

The role of cerebellum in seizure generation is debatable. Semiology and electroencephalography (EEG) findings are non-specific and sometimes misleading, posing further difficulty in proving the epileptogenicity in pre-surgical workup. We report two cases of cerebellar lesions who presented with hemifacial seizures since the neonatal period and were refractory to antiepileptic drugs (AEDs). Read More

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http://dx.doi.org/10.4103/0028-3886.253622DOI Listing
December 2019
42 Reads

Detection of epileptogenic focus with two new methods of processing of SPECT and PET cerebral images: PET-Analysis and PISCOM.

Rev Esp Med Nucl Imagen Mol 2019 Sep - Oct;38(5):312-315. Epub 2019 Feb 28.

Departamento de Medicina Nuclear, Hospital Clínic, Barcelona, España; Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Universidad de Barcelona, Barcelona, España.

Functional neuroimaging with positron emission tomography with F-fluorodeoxyglucose (PET-F-FDG) and perfusion single photon emission computerized tomography (SPECT) are increasingly more essential for presurgically locating the epileptogenic focus. We present the case of an 18-year-old male with epileptic seizures refractory to antiepileptic treatment. Magnetic resonance (MR) showed dysplasia in the posterior right insular cortex. Read More

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http://dx.doi.org/10.1016/j.remn.2019.01.002DOI Listing
May 2020
1 Read

Rosette-Forming Glioneuronal Tumor in Opticochiasmatic Region-Novel Entity in New Location.

World Neurosurg 2019 05 18;125:253-256. Epub 2019 Feb 18.

Department of Neurosciences, Sakra World Hospital, Bellandur, Bangalore, Karnataka, India.

Background: Rosette-forming glioneuronal tumour [RGNT] is a relatively rare entity first identified as a separate entity in 2002. We are reporting the second case of RGNT in the opticochiasmatic region.

Case Description: We report a case report and literature review of RGNT with syndromic association. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.003DOI Listing
May 2019
4 Reads

Hyperadrenocorticism Caused by a Pituitary Ganglioglioma in a Dog.

Vet Pathol 2019 07 17;56(4):609-613. Epub 2019 Feb 17.

5 Laboratory of Veterinary Surgery, Department of Veterinary Clinical Medicine, Faculty of Veterinary Medicine, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino-shi, Tokyo, Japan.

An 11-year-old castrated male Chihuahua dog was presented with complaints of polyuria, polydipsia, abdominal enlargement, and alopecia. Hyperadrenocorticism was diagnosed on the basis of clinical signs, blood tests, adrenocorticotropin-stimulation test results, and an elevated serum adrenocorticotropin concentration. Contrast-enhanced magnetic resonance imaging showed that the pituitary gland was enlarged, compatible with a pituitary macroadenoma. Read More

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http://dx.doi.org/10.1177/0300985819829530DOI Listing
July 2019
2 Reads

Ganglioglioma Arising from the Septum Pellucidum: Case Report and Review of the Literature.

Pediatr Neurosurg 2019 8;54(1):36-45. Epub 2019 Jan 8.

Department of Neurological Surgery, University of Virginia Health Science Center, University of Virginia, Charlottesville, Virginia, USA,

Background: Gangliogliomas are low-grade neoplasms that typically affect patients under the age of 30 and present with epilepsy and symptoms of mass effect. Here, we report a case of an intraventricular ganglioglioma involving the septum pellucidum in a pediatric patient with history of optic glioma. Only one other pediatric intraventricular ganglioglioma arising from the septum pellucidum has been reported previously. Read More

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https://www.karger.com/Article/FullText/495043
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http://dx.doi.org/10.1159/000495043DOI Listing
April 2019
38 Reads

Discrimination of epileptogenic lesions and perilesional white matter using diffusion tensor magnetic resonance imaging.

Neuroradiol J 2019 Feb 21;32(1):10-16. Epub 2018 Nov 21.

1 Department of Neuroradiology, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

The aim of this study was to evaluate whether ganglioglioma (GGL), dysembryoplastic neuroepithelial tumour (DNET) and FCD (focal cortical dysplasia) are distinguishable through diffusion tensor imaging. Additionally, it was investigated whether the diffusion measures differed in the perilesional (pNAWM) and in the contralateral normal appearing white matter (cNAWM). Six GGLs, eight DNETs and seven FCDs were included in this study. Read More

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http://dx.doi.org/10.1177/1971400918813991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327366PMC
February 2019
17 Reads

Cervicomedullary Ganglioglioma in a Child - A Case Report.

Prague Med Rep 2018;119(2-3):122-127

Department of Neurosurgery, Iran University of Medical Sciences, Rasool Akram Hospital, Tehran, Iran.

Ganglioglioma is a benign slow-growing neoplasm that most frequently occurs at the supratentorial region. Nevertheless, there are occasional reports of ganglioglioma occurring in the brainstem and spinal cord. Here we report a rare case of the craniocervical ganglioglioma. Read More

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https://pmr.lf1.cuni.cz/119/2/0122/
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http://dx.doi.org/10.14712/23362936.2018.12DOI Listing
April 2019
28 Reads

Stereotactic Brain Biopsy in Eloquent Areas Assisted by Navigated Transcranial Magnetic Stimulation: a Technical Case Report.

Oper Neurosurg (Hagerstown) 2019 09;17(3):E124-E129

Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.

Background And Importance: Stereotactic brain biopsy (SB) is an important part of the neurosurgical armamentarium, with the possibility of achieving histopathological diagnosis in otherwise inaccessible lesions of the brain. Nevertheless, the procedure is not without the risk of morbidity, which is especially true for lesions in eloquent parts of the brain, where even a minor adverse event can result in significant deficits. Navigated transcranial magnetic stimulation (nTMS) is widely used to chart lesions in eloquent areas, successfully guiding maximal safe resection, while its potential role in aiding with the planning of a stereotactic biopsy is so far unexplored. Read More

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https://academic.oup.com/ons/advance-article/doi/10.1093/ons
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http://dx.doi.org/10.1093/ons/opy321DOI Listing
September 2019
10 Reads

CD34 Expression in Low-Grade Epilepsy-Associated Tumors: Relationships with Clinicopathologic Features.

World Neurosurg 2019 Jan 9;121:e761-e768. Epub 2018 Oct 9.

Neurosurgery Unit, Department of Neuroscience, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

Objective: To analyze relationships between CD34 expression and several demographic, clinical, and pathologic features in patients with histopathologic evidence of low-grade epilepsy-associated tumors who underwent epilepsy surgery.

Methods: A retrospective study enrolling 187 patients with low-grade epilepsy-associated tumors who underwent surgery between January 2009 and June 2015 at 8 Italian epilepsy surgery centers was conducted. All cases were histologically diagnosed according to the World Health Organization classification of central nervous system tumors. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.212DOI Listing
January 2019
15 Reads

Inflammatory myofibroblastic lung tumor transforming into intracranial desmoplastic noninfantile ganglioglioma: A case report and literature review.

Medicine (Baltimore) 2018 Oct;97(40):e12668

Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu.

Rationale: Inflammatory myofibroblastic tumor (IMT) of the lung often arises from excessive inflammatory response. It is one of the rare benign tumors of the lung, while desmoplastic noninfant gangliogliomas (DNIG), on the contrary, are rare intracranial benign tumors often seen in children within the first one and a half years of life.

Patient Concerns: We present a 12-year-old girl with 2 months history of none productive cough and right-sided chest pain. Read More

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http://Insights.ovid.com/crossref?an=00005792-201810050-0006
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http://dx.doi.org/10.1097/MD.0000000000012668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200452PMC
October 2018
6 Reads
5.723 Impact Factor

Post-treatment maturation of medulloblastoma in children: two cases and a literature review.

J Int Med Res 2018 Nov 1;46(11):4781-4790. Epub 2018 Oct 1.

Department of Neurosurgery, Children's Hospital of Chongqing Medical University, Chongqing, China.

We herein report two cases of post-treatment maturation of medulloblastoma (MB). We also conducted a literature review to summarize the clinical and pathologic features of MB maturation. From January 1992 to February 2017, 52 patients with MB underwent surgical resection followed by radiotherapy and chemotherapy. Read More

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http://dx.doi.org/10.1177/0300060518788251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259389PMC
November 2018
20 Reads

BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors.

Nat Med 2018 11 17;24(11):1662-1668. Epub 2018 Sep 17.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

Pediatric brain tumors are highly associated with epileptic seizures. However, their epileptogenic mechanisms remain unclear. Here, we show that the oncogenic BRAF somatic mutation p. Read More

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http://www.nature.com/articles/s41591-018-0172-x
Publisher Site
http://dx.doi.org/10.1038/s41591-018-0172-xDOI Listing
November 2018
32 Reads
1 Citation
27.363 Impact Factor

[BRAF V600E mutation and clinicopathologic characteristics in 250 cases of brain tumors associated with epilepsy].

Zhonghua Bing Li Xue Za Zhi 2018 Sep;47(9):664-670

Department of Pathology, Capital Medical University, Beijing 100010, China.

To investigate the clinicopathologic characteristics and BRAF V600E mutation of brain tumors associated with epilepsy. Totally 250 patients with brain tumors associated with epilepsy were included from March 2008 to August 2017 retrospectively at Sanbo Brain Hospital, Capital Medical University.The clinical manifestations, histological features and BRAF V600E mutation results were collected and analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.09.003DOI Listing
September 2018
8 Reads

Meningioma mimicking an intraparenchymal cystic tumor.

Nagoya J Med Sci 2018 Aug;80(3):431-434

Department of Neurosurgery, Sapporo Medical University School of Medicine, Sapporo, Japan.

Meningiomas rarely exhibit cystic lesions with mural nodules, and may be misdiagnosed as intraparenchymal cystic tumors. We herein present a 64-year-old woman with a cystic lesion and enhancing mural nodule in the left temporal lobe accompanied by peritumoral brain edema. Differential diagnoses included low-grade gliomas, hemangioblastoma, and cystic meningioma. Read More

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http://dx.doi.org/10.18999/nagjms.80.3.431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125649PMC
August 2018
9 Reads

Pipeline-assisted coil embolization of a large middle cerebral artery pseudoaneurysm in a 9-month-old infant: experience from the youngest flow diversion case.

J Neurosurg Pediatr 2018 Nov;22(5):532-540

1Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland.

Intracranial aneurysms in the pediatric population are rare entities. The authors recently treated a 9-month-old infant with a 19-mm recurrent, previously ruptured, and coil-embolized left middle cerebral artery (MCA) pseudoaneurysm, which was treated definitively with single-stage Pipeline-assisted coil embolization. The patient was 5 months old when she underwent resection of a left temporal Grade 1 desmoplastic infantile ganglioglioma at an outside institution, which was complicated by left MCA injury with a resultant 9-mm left M1 pseudoaneurysm. Read More

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http://dx.doi.org/10.3171/2018.6.PEDS18165DOI Listing
November 2018
13 Reads

Pediatric primary anaplastic ganglioglioma with malignant neuronal component.

Turk J Pediatr 2018 ;60(1):102-106

Departments of Pediatrics, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.

Kaymak-Cihan M, Erdiş E, Bozkurt S, Ünver-Korğalı E. Pediatric primary anaplastic ganglioglioma with malignant neuronal component. Turk J Pediatr 2018; 60: 102-106. Read More

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http://dx.doi.org/10.24953/turkjped.2018.01.017DOI Listing
January 2019
14 Reads

Pediatric Intracranial Anaplastic Gangliogliomas: Illustrative Case and Systematic Review.

World Neurosurg 2018 Nov 8;119:220-231. Epub 2018 Aug 8.

Department of Neurosurgery, Mongi Ben Hamida National Institute of Neurology Tunis, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.

Objective: We present an illustrative case of pediatric intracranial anaplastic ganglioglioma and systematically reviewed the current reported data of anaplastic ganglioglioma in the pediatric population.

Methods: A comprehensive literature search for our review was conducted using PubMed, Scopus, Web of Science, PsycINFO, Cochrane, and Embase databases. The search terms included "ganglioglioma," "anaplastic," "pediatrics," "children," and "intracranial. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.278DOI Listing
November 2018
11 Reads
2.417 Impact Factor

Surgical Treatment of Lesional Mesial Temporal Lobe Epilepsy.

J Epilepsy Res 2018 Jun 30;8(1):6-11. Epub 2018 Jun 30.

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Korea.

Lesional mesial temporal lobe epilepsy (mTLE) concerns a lesion other than mesial hippocampal sclerosis present in the mesial temporal lobe and causing seizures. The lesions are usually composed of focal cortical dysplasia (FCD) or are tumorous. These are good candidates for surgical treatment. Read More

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http://dx.doi.org/10.14581/jer.18002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066696PMC
June 2018
24 Reads

Ganglioglioma of the adenohypophysis mimicking pituitary adenoma: A case report and review of the literature.

Medicine (Baltimore) 2018 Jul;97(30):e11583

Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine.

Introduction: Ganglioglioma is a generally benign tumor, mostly occurring in patients <30 years old. Temporal lobe is most frequently involved. Up to now, only 3 cases were reported of ganglioglioma in the pituitary gland, all being confined to the neurohypophysis. Read More

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http://dx.doi.org/10.1097/MD.0000000000011583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078729PMC
July 2018
18 Reads