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Diagn Pathol 2019 Mar 13;14(1):22. Epub 2019 Mar 13.

Department of Radiology, Maisonneuve-Rosemont Hospital, 5415 Boulevard de L'Assomption, Montreal, QC, Canada.

Background: Malakoplakia is a chronic inflammatory disease characterized by tissue infiltrates of large granular macrophages containing distinctive intracytoplasmic inclusions termed Michaelis-Gutmann (MG) bodies. The genitourinary system is the most commonly involved site, followed by the gastrointestinal tract. Malakoplakia may occur as a complication of primary or secondary immunosuppression and, therefore, renal transplant recipients are at risk. Read More

N Engl J Med 2018 Oct;379(17):1635-1642

From the Division of Colon and Rectal Surgery, Mayo Clinic, Phoenix, AZ.

Medicine (Baltimore) 2018 Oct;97(40):e12712

Department of Diagnostic Radiology, Chang Gung Memorial Hospital Chiayi Branch, Chiayi.

Rationale: Failure to recognize intestinal malrotation in adults can cause complications during surgeries, especially those with a limited operative field. We report a case of short bowel syndrome caused by mistaken creation of a loop enterostomy in the jejunum due to undiagnosed intestinal malrotation.

Patient Concerns: A 72-year-old man underwent a laparoscopic right hemicolectomy and ileocolostomy because of complicated diverticulitis. Read More

Dis Colon Rectum 2018 Oct;61(10):1141-1144

Division of General Surgery, University of Utah, Salt Lake City, Utah.

Ann R Coll Surg Engl 2018 Aug 16:e1-e3. Epub 2018 Aug 16.

First Department of Surgery, Laikon General Hospital, School of Medicine, National and Kapodistrian University of Athens , Athens , Greece.

The transverse colon is a particularly rare site for a diverticulum to develop, with only few reports of solitary diverticula described in the literature. Among the reported complications, colocutaneous fistulas appear relatively infrequently. We describe the case of an 80-year-old woman with a solitary diverticulum of the transverse colon presenting as acute diverticulitis with abscess formation in the epigastric region. Read More

Gastrointest Endosc 2018 11 20;88(5):841-853.e4. Epub 2018 Jul 20.

Department of Gastroenterology and Hepatology, Kohnodai Hospital, National Center for Global Health and Medicine, Chiba, Japan.

Background And Aims: Very few prospective studies with over 100 samples have evaluated the long-term outcomes of endoscopic therapy for colonic diverticular bleeding (CDB). This study sought to elucidate the recurrent bleeding risk of endoscopic band ligation versus clipping for definitive CDB based on stigmata of recent hemorrhage (SRH).

Methods: Patients emergently hospitalized for acute lower GI bleeding and examined by high-resolution colonoscopy were enrolled. Read More

Clin Colon Rectal Surg 2018 Jul 22;31(4):217-220. Epub 2018 Jun 22.

Division of Colon and Rectal Surgery, Department of Surgery, Henry Ford Hospital, Detroit, Michigan.

Radiologic assessment plays a vital role in the management of diverticulitis. It not only helps in the diagnosis, but also helps to guide the management. As technology has progressed, different modalities have offered insight into the treatment of this disease process. Read More

Expert Rev Gastroenterol Hepatol 2018 Aug 19;12(8):791-796. Epub 2018 Jun 19.

a Gastroenterology Service , ASL BAT , Andria , Italy.

Introduction: Diverticulosis of the colon is a common condition, and about one-fourth of those people develop symptoms, which is called 'diverticular disease' (DD). Since there are still some concerns about the diagnosis of DD, the aim of this review was to analyze current and evolving advances in its diagnosis. Area covered: Analysis of clinical, radiology, laboratory, and endoscopic tools to pose a correct diagnosis of DD was performed according to current PubMed literature. Read More

Ann Surg Treat Res 2018 Jun 29;94(6):322-329. Epub 2018 May 29.

Department of Surgery, Daegu Catholic University Medical Center, Catholic University of Daegu School of Medicine, Daegu, Korea.

Purpose: The incidence of colonic diverticular disease is increasing, and several grading systems based on CT findings have been developed. The objective of this study was to define the impact of various CT findings of colonic diverticulitis and to demonstrate which factors affect the need for operative treatment.

Methods: Three hundred fifty-seven patients diagnosed with colonic diverticulitis from January 2010 to July 2016 were retrospectively evaluated. Read More

Indian J Radiol Imaging 2018 Jan-Mar;28(1):37-40

Department of Radiodiagnosis, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India.

Colouterine fistula is an extremely rare condition, as the uterus is a thick, muscular organ. Here, we present two different etiologies for this rare condition-diverticulitis and malignancy. A 77-year-old female with colouterine fistula due to diverticulitis presented with complaints of lower abdominal pain localized particularly in the left iliac fossa and fever. Read More

Gastroenterol Nurs 2018 Mar/Apr;41(2):111-119

Lenore Lamanna, EdD, RN, ANP-BC, is with Stony Brook University, Stony Brook, New York; and is Clinical Associate Professor, Graduate Studies in Advanced Practice Nursing, Nurse Practitioner Gastroenterology Associates of Suffolk, Smithtown, New York. Patricia E. Moran, DNP, RN, ANP-C, is with Stony Brook University, New York; and is Clinical Assistant Professor, Graduate Studies in Advanced Practice Nursing.

Diverticular disease includes diverticulosis, which are sac protrusions of the intestinal mucosa, and diverticulitis, inflammation of the diverticula. Diverticular disease is listed as one of the top 10 leading physician diagnoses for gastrointestinal disorders in outpatient clinic visits in the United States. There are several classifications of diverticular disease ranging from asymptomatic diverticulosis to diverticulitis with complications. Read More

Vasc Endovascular Surg 2018 Jul 19;52(5):386-390. Epub 2018 Mar 19.

1 Division of Colorectal Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.

Aortic graft infections are a rare but devastating complication of aortic revascularization. Often infections occur due to contamination at the time of surgery. Iatrogenic misplacement of the limbs of an aortobifemoral graft is exceedingly rare, and principles of evaluation and treatment are not well defined. Read More

Int J Colorectal Dis 2018 Jun 12;33(6):827-829. Epub 2018 Mar 12.

Department of Gastroenterology, Hospital Clínico de Valladolid, Av Ramón y Cajal 3, 47003, Valladolid, Spain.

Introduction: The development of novel mechanical endoscopic closure systems allows now the management of some gastrointestinal fistula types in a minimally invasive way. However, the correct location of the fistulous tract is essential to achieve successful endoscopic closure.

Case Report: A 69-year-old woman with high risk for surgery presented with recurrent cystitis, pneumaturia, and enteruria 2 months after medical-treated diverticulitis. Read More

Crit Care Nurs Clin North Am 2018 Mar 29;30(1):67-74. Epub 2017 Nov 29.

Austin Peay State University, School of Nursing, 601 College Street, Clarksville, TN 37043, USA. Electronic address:

Diverticular disease accounts for approximately 300,000 hospitalizations per year in the United States, resulting in 1.5 million days of inpatient care. Diverticulitis is defined as an inflammation of the diverticulum, which can be asymptomatic or symptomatic. Read More

Int J Colorectal Dis 2018 Mar 3;33(3):317-326. Epub 2018 Feb 3.

Department of General-, Visceral- and Vascular Surgery, Charité University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany.

Purpose: It is controversial whether patients fare better with conservative or surgical treatment in certain stages of acute diverticulitis (AD), in particular when phlegmonous inflammation or covered micro- or macro-perforation are present. The aim of this study was to determine long-term quality of life (QoL) for AD patients who received either surgery or conservative treatment in different stages.

Methods: We included patients treated for AD at the University Hospital Grosshadern, Munich, Germany, between January 1, 2000, and December 31, 2010. Read More

J Enzyme Inhib Med Chem 2018 Dec;33(1):428-432

c Faculty of Medecine , Titu Maiorescu University , Bucharest , Romania.

The gamma-glutamyltransferase (GGT) is recognized in medical practice as a useful indicator for the detection of liver lesions, especially those induced by the excessive consumption of alcoholic or cholesterol-associated drinks. The present study, although it includes a very small number of cases diagnosed with colon diverticulosis-diverticulitis associated with polyposis at the same intestinal level, identifies the presence of increased circulating concentrations of this enzyme in the serum. Its serum levels are tracked "dynamically" throughout a year after the diagnosis and start of the therapy. Read More

Minerva Chir 2018 Apr 23;73(2):163-178. Epub 2018 Jan 23.

Unit of Coloproctology, Hospital Vithas-Nisa 9 de Octubre, Valencia, Spain.

Diverticulitis is a common condition in industrialized countries and an important cause of hospital admissions. Its growing trend is a challenge for the surgeons who perform emergency surgery, because approximately 15-25% of the patients will require surgery, being the surgical management of complicated acute diverticulitis controversial. The past decade has seen a paradigm shift in the treatment of sigmoid diverticulitis based on new epidemiological studies and refinement of surgical techniques that has produced a reassessment of our guidelines. Read More

Gan To Kagaku Ryoho 2018 Jan;45(1):124-126

Dept. of Surgery, Fuchu Hospital.

A 52-year-old woman presented with sudden left lower abdominal pain, fever, and vomiting. As the symptom got improved immediately she went home then. She consulted our hospital with chief complaint of the left lower abdominal mass. Read More

Abdom Radiol (NY) 2018 Aug;43(8):2060-2065

Department of Radiology, Boston University Medical Center, Boston, MA, USA.

Purpose: To assess whether CT findings, clinical parameters, and modified Hinchey classification are predictive of management outcomes of patients with acute diverticulitis.

Materials And Methods: Data were accrued between January 2014 and December 2015. A total of 301 adult subjects were identified from radiology reports, of which six who did not met the inclusion criteria were excluded, thus yielding 295 subjects. Read More

Swiss Med Wkly 2017 23;147:w14555. Epub 2017 Nov 23.

Department of Internal Medicine, Kantonsspital Olten soH, Switzerland.

Aims Of The Study: While studies show that antibiotic treatment for uncomplicated diverticulitis seems to have no benefit, most experts advocate antimicrobial therapy for complicated diverticulitis. However, even for uncomplicated diverticulitis, most clinicians are very reluctant to withhold antibiotics. Biomarkers could help to guide antibiotic therapy as this approach has been shown to be effective for acute respiratory infections. Read More

J Surg Case Rep 2017 Nov 21;2017(11):rjx228. Epub 2017 Nov 21.

Englewood Hospital and Medical Center, Englewood, NJ 07631,USA.

Colo-ovarian fistula is a rare entity. The case of a 54-year-old female with a colo-ovarian fistula is presented. We describe our experience in managing this complication of diverticulitis and propose a workup and treatment plan. Read More

Case Rep Emerg Med 2017 2;2017:2563218. Epub 2017 Oct 2.

Department of Emergency Medicine, Rowan University-SOM/Kennedy University Hospital, Stratford, NJ, USA.

We report a case of a 71-year-old female who presented with right lower quadrant (RLQ) abdominal pain and was diagnosed on CT scan with right-sided diverticulitis with perforation. She was admitted under the surgical service after consultation and received intravenous fluids, intravenous antibiotics, and pain medications as needed. The patient was discharged 2 days after admission in stable condition with follow-up with gastroenterology. Read More

Int J Colorectal Dis 2017 Dec 26;32(12):1693-1698. Epub 2017 Oct 26.

Department of Surgery, Academic Medical Center, Meibergdreef 9, 1100 DD, PO Box 22660, Amsterdam, The Netherlands.

Purpose: Since outpatient treatment and omitting antibiotics for uncomplicated acute colonic diverticulitis have been proven to be safe in the majority of patients, selection of patients that may not be suited for this treatment strategy becomes an important topic. The aim of this study is to identify computed tomography (CT) imaging predictors for a complicated disease course of initially uncomplicated acute diverticulitis.

Methods: CT imaging from a randomized controlled trial (DIABOLO study) of an observational vs. Read More

Medicine (Baltimore) 2017 Oct;96(43):e8358

aDepartment of General and Visceral Surgery, EHC Hospital, Morges b Department of Visceral Surgery, University Hospital CHUV, Lausanne cUnilabs, Department of Pathology, Lausanne, Switzerland.

Rationale: Acute colonic diverticulitis is a well-known surgical emergency, which occurs in about 10 percent of patients known for diverticulosis.

Patient Concerns: The case of a 77-year-old woman is reported, with past history of abdominoperineal resection with end-colostomy for low rectal adenocarcinoma, and who developed an acute colonic diverticulitis in a subcutaneous portion of colostomy with parastomal phlegmon.

Diagnoses: Initial computed tomography imaging demonstrated a significant submucosal parietal edema with local fat tissues infiltration in regard of 3 diverticula. Read More

Eur J Vasc Endovasc Surg 2018 Feb 16;55(2):205. Epub 2017 Oct 16.

Department of Cardiovascular Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address:

AJR Am J Roentgenol 2017 Dec 5;209(6):1263-1271. Epub 2017 Oct 5.

3 Department of Radiology, Chungnam National University School of Medicine, Daejeon, Korea.

Objective: The purpose of this study was to retrospectively assess CT predictors of unfavorable outcomes of medical treatment in patients with right colonic diverticulitis.

Materials And Methods: Of 394 patients with right colonic diverticulitis diagnosed on the basis of CT findings from January 2010 through August 2013, we included 328 (190 men, 138 women; mean age, 41.3 ± 12. Read More

Transplant Proc 2017 Oct;49(8):1960-1962

Department of Surgery, University of Washington Medical Center, University of Washington, Seattle, Washington. Electronic address:

Background: Complicated diverticulitis after transplantation occurs in as many as 3.5% of cases and carries a 25% mortality rate. Diagnosis of complicated diverticulitis in this population can be challenging because of abnormal presentations caused by immunosuppression. Read More

Radiology 2017 12 24;285(3):850-858. Epub 2017 Aug 24.

From the Division of Abdominal Radiology, Department of Radiology (E.C.D., J.H.E., M.S.D., M.A., R.H.C.); Division of Emergency Radiology, Department of Radiology (S.T.C., M.B.M.), Michigan Institute for Clinical and Health Research (K.W.), Department of Biostatistics, School of Public Health (B.N.), Division of Gastroenterology, Department of Internal Medicine (R.R.), and Division of Colorectal Surgery, Division of General Surgery, Department of Surgery (A.M.M.), University of Michigan Health System, 1500 E Medical Center Dr, Ann Arbor, MI 48109-5030.

Purpose To identify computed tomographic (CT) findings that are predictive of recurrence of colonic diverticulitis. Materials and Methods Institutional review board approval was obtained for this HIPAA-compliant, retrospective cohort study. Six abdominal fellowship-trained radiologists reviewed the CT studies of 440 consecutive subjects diagnosed with acute colonic diverticulitis between January 2004 and May 2008 to determine the involved segments, maximum wall thickness in the inflamed segment, severity of diverticulosis, presence of complications (abscess, fistula, stricture, or perforation), and severity of the inflammation. Read More

Khirurgiia (Mosk) 2017(8):51-57

Sklifosovsky Research Institute for Emergency Care, Health Care Department of Moscow, Moscow, Russia.

Aim: To assess an effectiveness of minimally invasive and laparoscopic technologies in treatment of inflammatory complications of colic diverticular disease.

Material And Methods: The study included 150 patients who were divided into control and main groups. Survey included ultrasound, X-ray examination and abdominal computerized tomography. Read More

Adv Surg 2017 09 6;51(1):179-191. Epub 2017 May 6.

Division of Colorectal Surgery, Department of Surgery, Stony Brook School of Medicine, Stony Brook, NY 11794, USA.

Int J Colorectal Dis 2017 Sep 29;32(9):1313-1319. Epub 2017 Jun 29.

Department of Visceral Surgery, Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011, Lausanne, Switzerland.

Purpose: Antibiotic treatment is the treatment of choice for uncomplicated diverticulitis (uD) and can be performed for mild complicated diverticulitis (mcD). In several cases, outpatient treatment (OT) can be undertaken. This study assessed the 1-month failure rate of OT for uD/mcD compared to inpatient treatment (IT), and identified predictive factors for treatment failure. Read More

Clin Nucl Med 2017 Aug;42(8):e365-e366

From the Departments of *Nuclear Medicine, and †Pathology, Keimyung University Dongsan Medical Center, Daegu; and ‡Department of Nuclear Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea.

A 77-year-old man with anorexia and weight loss for 6 months received a diagnosis of gastric cancer by endoscopy and referred for F-FDG PET/CT for initial staging. F-FDG PET/CT showed multiple foci of increased FDG uptake with diffuse wall thickening and multiple diverticula. The differential diagnoses were peritoneal seeding and multiple diverticulitis. Read More

Exp Ther Med 2017 May 9;13(5):1932-1936. Epub 2017 Mar 9.

Department of Neurosurgery, National Hospital Organization Shimoshizu Hospital, Yotsukaido, Chiba 284-0003, Japan.

The utility and limitations of abdominal ultrasonography (US) were retrospectively evaluated as a first-line diagnostic imaging modality in patients with abdominal pain. Hospital records from patients subjected to abdominal US as a first-line diagnostic imaging examination at the National Hospital Organization Shimoshizu Hospital (Yotsukaido, Japan) from April 2010 to April 2015 were analyzed. Only those patients who underwent abdominal US to diagnose abdominal symptoms were included in the present study. Read More

J Dig Dis 2017 Jul;18(7):379-387

Department of General and Digestive Surgery, Reina Sofia University Hospital, Cordoba, Spain.

Objective: Acute diverticulitis (AD) is becoming a health concern with its increasing incidence. One of the accepted theories of the possible causes of diverticular perforation is the impaction of fecal residuals into some diverticula. We aimed to evaluate whether barium impaction had a negative effect by promoting diverticular inflammation or rupture and thereby AD recurrence. Read More

Rom J Morphol Embryol 2017 ;58(1):249-253

Department of Internal Medicine, Department of Nephrology, Faculty of Medicine, "Ovidius" University of Constanta, Emergency County Hospital, Constanta, Romania;

Diverticular disease is frequent amongst the elderly and immunosuppressed patients. It mainly presents as sigmoid diverticulitis, but severe complications, like bleedings, infections and colon perforation may occur, frequently due to immunosuppressive therapy. Moreover, antibiotherapy and hemostatics may not efficiently control evolution in such cases. Read More

Abdom Radiol (NY) 2017 11;42(11):2597-2608

Department of Radiology, Northwell Health System, Hofstra Northwell School of Medicine, Manhasset, NY, USA.

Large bowel perforation is an abdominal emergency that results from a wide range of etiologies. Computed tomography is the most reliable modality in detecting the site of large bowel perforation. The diagnosis is made by identifying direct CT findings such as extraluminal gas or contrast and discontinuity along the bowel wall. Read More

J Am Coll Surg 2017 Jul 24;225(1):21-25. Epub 2017 Apr 24.

Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, Minneapolis, MN. Electronic address:

Background: Inpatient treatment of patients with colon diverticulitis represents a significant financial and clinical burden to the health care system and patients. The aim of this study was to compare patients with diverticulitis in the emergency department (ED), who were discharged to home vs admitted to the hospital.

Study Design: We reviewed all patients evaluated in the ED of a metropolitan health system, with the primary diagnosis of diverticulitis (ICD-9 562. Read More

Radiol Bras 2017 Mar-Apr;50(2):126-131

Specialist in Coloproctology, Preceptor at the Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brazil.

Acute diverticulitis of the colon is a common indication for computed tomography, and its diagnosis and complications are essential to determining the proper treatment and establishing the prognosis. The adaptation of the surgical classification for computed tomography has allowed the extent of intestinal inflammation to be established, the computed tomography findings correlating with the indication for treatment. In addition, computed tomography has proven able to distinguish among the main differential diagnoses of diverticulitis. Read More

J Med Case Rep 2017 Apr 13;11(1):106. Epub 2017 Apr 13.

Division of Critical Care, Department of Medicine, London Health Sciences Centre, Western University, London, ON, Canada.

Background: Patients with diverticulitis are predisposed to hepatic abscesses via seeding through the portal circulation. Hepatic abscesses are well-documented sequelae of diverticulitis, however instances of progression to hepato-bronchial fistulization are rare. We present a case of diverticulitis associated with hepatic abscess leading to hepato-bronchial fistulization, which represents a novel disease course not yet reported in the literature. Read More

Urology 2017 Jun 18;104:e1-e2. Epub 2017 Mar 18.

Department of Urology, University of Illinois at Chicago, Chicago, IL.

Our patient presented with dysuria and pneumaturia without any prior urologic instrumentation. History included choledocolithiasis requiring endoscopic retrograde cholangiopancreatography and biliary stenting. Imaging showed a large bladder stone. Read More

Ulus Travma Acil Cerrahi Derg 2017 Jan;23(1):61-65

Department of General Surgery, Bezmialem Vakıf University Faculty of Medicine, İstanbul-Turkey.

Background: Diverticulosis of the right colon is an uncommon entity. Aim of the present study was to report outcome in patients with right-sided diverticulitis diagnosed using computed tomography (CT) and treated conservatively.

Methods: Twelve patients with clinical and radiological diagnosis of cecal or right-sided diverticulitis who were treated conservatively between February 2013 and December 2014 were included. Read More

Minerva Gastroenterol Dietol 2017 Jun 24;63(2):158-162. Epub 2017 Feb 24.

Department of Surgery, S-SPIRE Center, Stanford University School of Medicine, Stanford, CA, USA.

Sigmoid diverticulitis is an increasingly common disease in Western countries. As technology has led to increased knowledge about the disease and options for treatment, management strategies have become less certain. In previous years, the rationale for early elective surgery was largely preventive, due to concern that diverticulitis recurrence would result in increased risk of sepsis or the need for a colostomy. Read More

Am Surg 2016 Nov;82(11):301-302

General Surgery Residency, Kendall Regional Medical Center, Miami, Florida, USA.

Int J Colorectal Dis 2017 Apr 29;32(4):485-489. Epub 2016 Dec 29.

Department of General Surgery, Dandenong Hospital, Monash Health, 135 David Street, Dandenong, VIC, 3175, Australia.

Purpose: WHO GLOBOCAN 2012 data showed that Australia and New Zealand have the highest incidence rates of colorectal cancer in the world (Ferlay et al. 1). Current guidelines recommend that patients admitted for an episode of acute diverticulitis require an early follow-up colonoscopy to rule out colorectal malignancy as reported by Fozard et al. Read More

Turk J Gastroenterol 2017 Jan 23;28(1):60-62. Epub 2016 Dec 23.

Gastroenterology UO, Bellaria-Maggiore Hospital, Bologna, Italy.

Endoscopy 2016 0;48(S 01):E374-E375. Epub 2016 Nov 22.

Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, Serbia.

Abdom Radiol (NY) 2017 03;42(3):810-817

Department of Medical Imaging, Saint Joseph Hospital, 185 Rue Raymond Losserand, 75014, Paris, France.

Purpose: To compare clinical features, computed tomography (CT) findings, and outcomes of right vs. left colonic diverticulitis (CD) in Caucasians.

Methods: This single-center retrospective case-control study of patients seen between July 2005 and February 2013 included 30 consecutive cases of right CD and 70 controls taken at random from a consecutive cohort of patients with left CD. Read More

Cir Esp 2016 Dec 5;94(10):553-559. Epub 2016 Nov 5.

Departamento de Cirugía General y Digestiva, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, España.

The aim of this narrative review is to define the clinical-pathological characteristics and to clarify the management of right colonic diverticular disease. It is rare in Europe, USA and Australia and more common in Asia. In the recent years its incidence has increased in the West, with various distributions among populations. Read More

Am J Surg 2016 Nov 7;212(5):837-843. Epub 2016 May 7.

Department of Surgery, Madigan Army Medical Center, 9040 Jackson Ave, Tacoma, WA 98431, USA.

Background: Modern 64- to 128-slice computed tomography (CT) scanners have questioned the need for routine colonoscopy after hospital admission for presumed uncomplicated diverticulitis.

Methods: This is a retrospective review of all patients (>18 years) who underwent planned colonoscopy after admission for Hinchey I or II acute diverticulitis (January 2009 to January 2014). The findings on the final radiologist report were then correlated with the colonoscopy results. Read More

Br J Surg 2017 Jan 30;104(1):52-61. Epub 2016 Sep 30.

Department of Surgery, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

Background: Antibiotics are advised in most guidelines on acute diverticulitis, despite a lack of evidence to support their routine use. This trial compared the effectiveness of a strategy with or without antibiotics for a first episode of uncomplicated acute diverticulitis.

Methods: Patients with CT-proven, primary, left-sided, uncomplicated, acute diverticulitis were included at 22 clinical sites in the Netherlands, and assigned randomly to an observational or antibiotic treatment strategy. Read More