199 results match your criteria Imaging in Congenital Lobar Emphysema


Congenital lung malformations : analysis of 27 cases.

Tunis Med 2020 Jun;98(6):505-512

Introduction: Congenital lung malformations (CLM) include a complex range of developmental abnormalities. Currently, most are diagnosed prenatally or during early childhood.

Objective: to investigate clinical and imaging findings of congenital lung malformations in children. Read More

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Successful Treatment of Congenital Lobar Emphysema in Multiple Lung Lobes in an English Bulldog Puppy.

J Am Anim Hosp Assoc 2021 Mar;57(2):96-100

A 5 mo old male intact English bulldog was evaluated at a veterinary referral hospital for acute respiratory distress and chronic difficulty breathing. Thoracic radiographs revealed multifocal pulmonary hyperinflation and hyperlucency suspected in the left caudal and accessory lung lobes. A thoracic computed tomography scan identified severe diffuse enlargement of the caudal subsegment of the left cranial lung lobe and the dorsal process of the accessory lung lobe, with parenchymal hypoattenuation, rounded margins, and thin pulmonary vessels. Read More

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Fetal ultrasound and magnetic resonance imaging: a primer on how to interpret prenatal lung lesions.

Pediatr Radiol 2020 12 30;50(13):1839-1854. Epub 2020 Nov 30.

Department of Radiology, National Maternity Hospital, Dublin, Ireland.

Fetal lung lesions include common lesions such as congenital pulmonary airway malformation (CPAM), bronchopulmonary sequestration (BPS) and combined CPAM-BPS hybrid lesions, as well as less common entities including congenital lobar emphysema/obstruction, bronchial atresia, bronchogenic cysts and rare malignant pulmonary lesions such as pleuropulmonary blastoma. Fetal lung lesions occur in approximately 1 in 15,000 live births and are thought to arise from a spectrum of abnormalities related to airway obstruction and malformation, with the lesion type depending on the timing of insult, level of bronchial tree involvement, and severity of obstruction. Lesions vary from small and asymptomatic to large and symptomatic with significant mass effect on surrounding structures. Read More

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December 2020

[UNILATERAL MULTI-CYSTIC LUNG DISEASE IN A PRETERM INFANT].

Harefuah 2020 Oct;159(10):735-738

Department of Neonatal Intensive Care, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

Introduction: Cystic diseases of the lung are a rare spectrum of anomalies, commonly diagnosed prenatally. We present a case of a newborn twin, born at 29 weeks gestational. The infant was diagnosed with respiratory distress syndrome shortly after birth, treated with surfactant by the INSURE method (intubation, surfactant administration, extubation) and required only short-term non-invasive ventilation. Read More

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October 2020

Congenital Lobar Emphysema in an Elderly Patient.

Am J Respir Crit Care Med 2020 12;202(11):1579-1580

Department of Thoracic Surgery, West-China Hospital, Sichuan University, Chengdu, China.

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December 2020

Managing Congenital Lobar Overinflation Associated with Congenital Heart Disease.

Authors:
Ranjit I Kylat

Children (Basel) 2020 Aug 28;7(9). Epub 2020 Aug 28.

Department of Pediatrics, University of Arizona, 1501 N Campbell Ave, Tucson, AZ 85724, USA.

The incidence of congenital lobar overinflation (CLO) is reported at 1 in 20,000-30,000 live births and represents 10% of all congenital lung malformations. The occurrence of concomitant congenital heart disease (CHD) and CLO ranges from 12% to 20%. There are diverging views in the management as to whether early lobectomy or repair of the cardiac defect, with the assumption that respiratory symptomatology would gradually resolve, or a combined lung and cardiac repair would be the ideal first step in the management. Read More

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Clinical and surgical aspects of congenital lobar over-inflation: a single center retrospective study.

J Cardiothorac Surg 2020 May 19;15(1):102. Epub 2020 May 19.

Department of Pediatrics, Qena Faculty of Medicine, South Valley University, Qena, Egypt.

Background: Congenital lobar overinflation (CLOI) is one of the most important causes of infantile respiratory distress (RD). We aim to evaluate our experience in CLOI management emphasizing on clinical features, diagnostic modalities, surgery and outcomes.

Methods: This is a retrospective study for all CLOI cases undergoing surgical management at Qena University Hospital. Read More

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A clinical guideline for structured assessment of CT-imaging in congenital lung abnormalities.

Paediatr Respir Rev 2021 Mar 20;37:80-88. Epub 2020 Feb 20.

Department of Paediatric Surgery, Erasmus University Medical Centre, Sophia Children's Hospital, Rotterdam, The Netherlands. Electronic address:

Objectives: To develop a clinical guideline for structured assessment and uniform reporting of congenital lung abnormalities (CLA) on Computed Tomography (CT)-scans.

Materials And Methods: A systematic literature search was conducted for articles describing CT-scan abnormalities of congenital pulmonary airway malformation (CPAM), bronchopulmonary sequestration (BPS), congenital lobar emphysema (CLE) and bronchogenic cyst (BC). A structured report using objective features of CLA was developed after consensus between a pediatric pulmonologist, radiologist and surgeon. Read More

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Congenital left upper lobe emphysema due to vascular pressure on a left tracheal bronchus.

Pediatr Int 2020 Mar 26;62(3):407-408. Epub 2020 Feb 26.

Pediatric Pulmonary Institute, Shaare Zedek Medical Center, School of Medicine, Affiliated to The Hebrew University, Jerusalem, Israel.

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Congenital Lobar Hyperinflation - A rare anomaly misdiagnosed as bronchiolitis: A case report.

J Pak Med Assoc 2020 Jan;70(1):197-199

Department of Pediatrics, Sharif Medical City Hospital, Lahore, Pakistan.

Congenital Lobar Hyperinflation is an overinflation of one or more than one lobes of the lung and is caused by an abnormal development of broncho-pulmonary segment. We report a case of a 2-month-old female who presentedin outpatient department with complaints of fever, cough and difficulty in breathing. This case was seen in January, 2018. Read More

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January 2020

Airway anomalies in cases of anomalous pulmonary venous connection - A single-center experience.

Ann Card Anaesth 2020 Jan-Mar;23(1):14-19

Department of Cardiothoracic Surgery, SSSIHMS, Bengaluru, Karnataka, India.

Background: Patients with congenital heart defects may present with concomitant defects involving other organ systems. Roughly 4 percent of this nature are airway anomalies. Presence of anomalous airways summon major challenge before the anesthesiologist, surgeon, and intensivist in the perioperative management of such patients. Read More

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[Clinical analysis of 96 cases of congenital cystic lung lesions in children].

Zhonghua Er Ke Za Zhi 2020 Jan;58(1):19-24

Department of Pathology, Tianjin Children's Hospital, Tianjin 300134, China.

To summarize the diagnosis, clinical manifestations, treatment and prognosis of congenital cystic lung lesions. A retrospective study described the clinical course of 96 patients (46 female and 50 male) diagnosed with congenital cystic lung lesions treated at the Tianjin Children's Hospital from January 2010 to March 2019. The clinical findings, imaging examinations, pathological findings, treatment and follow-up were analyzed. Read More

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January 2020

Outcomes of Cases of Prenatally-Diagnosed Congenital Pulmonary Airway Malformation.

Rev Bras Ginecol Obstet 2019 Nov 19;41(11):654-659. Epub 2019 Nov 19.

Division of Neonatology, Department of Pediatrics, Hacettepe University, Ankara, Turkey.

Objective:  To evaluate the outcomes of cases of prenatally-diagnosed congenital pulmonary airway malformation (CPAM).

Methods:  We retrospectively evaluated cases of prenatally-diagnosed CPAM between 2004 and 2018. Ultrasonographic features such as visualization of a fetal lung mass and heterogeneous pulmonary parenchyma were used for CPAM diagnosis. Read More

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November 2019

Case 28-2019: A 22-Year-Old Woman with Dyspnea and Chest Pain.

N Engl J Med 2019 09;381(11):1059-1067

From the Department of Pediatrics, UMass Memorial Medical Center, and the Department of Pediatrics, University of Massachusetts Medical School, Worcester (T.M.K.), the Departments of Pediatrics (M.E.L., T.B.K.), Radiology (B.P.L.), and Pathology (M.M.-K.), Massachusetts General Hospital, and the Departments of Pediatrics (M.E.L., T.B.K.), Radiology (B.P.L.), and Pathology (M.M.-K.), Harvard Medical School, Boston, and the Laboratory for Molecular Medicine, Partners HealthCare Personalized Medicine, Cambridge (M.H.H.) - all in Massachusetts.

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September 2019

Congenital lung lesions.

Semin Pediatr Surg 2019 Aug 18;28(4):150821. Epub 2019 Jul 18.

Fetal Treatment Center, Department of Surgery, University of California, San Francisco. Electronic address:

Diagnosis and management of congenital lung malformations has evolved dramatically over the past several decades. Advancement in imaging technology has enabled earlier, more definitive diagnoses and, consequently, more timely intervention in utero or after birth, when indicated. These advancements have increased overall survival rates to around 95% from historical rates of 60%. Read More

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Congenital segmental emphysema in an adult patient.

Authors:
A Gulsen

Niger J Clin Pract 2019 Aug;22(8):1163-1165

Department of Pneumology, Interdisciplinary Allergy Outpatient Clinic, Lübeck, Germany; Department of Pulmonary Diseases, Celal Bayar University Faculty of Medicine, Manisa, Turkey.

Congenital segmental emphysema (CSE) is a disease characterized by severe hyperinflation of a specific segment of the lung without any intrinsic or extrinsic compression. It is most commonly observed in neonates and young children with acute respiratory distress. It is usually unilateral, and the left upper lobe of the lung is most often affected. Read More

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Developmental lung anomalies in adults: A pictorial review.

Respir Med 2019 08 11;155:86-96. Epub 2019 Jul 11.

Vice Chair of Education, Director, Cardio-Thoracic Radiology, USA; University of Texas Health Science Center -UT Health, San Antonio, TX, USA. Electronic address:

Developmental lung anomalies represent a heterogeneous group of diverse, yet related abnormalities that involve the lung parenchyma, pulmonary vasculature or a combination of both-which usually present prenatally and in early childhood. However, a substantial number of cases go unnoticed during childhood and present either incidentally or with recurrent respiratory infections progressing into adulthood. Defective development of the tracheobronchial tree and the pulmonary vasculature are proposed to cause these developmental anomalies. Read More

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Congenital lobar emphysema: diagnosis and treatment options.

Int J Chron Obstruct Pulmon Dis 2019 1;14:921-928. Epub 2019 May 1.

Department of Pediatrics, Division of Pediatric Pulmonology, Erciyes University, Kayseri, Turkey.

Although congenital lobar emphysema is a rare lung disease, it can cause severe respiratory distress in the newborn. Lobectomy can be difficult because of the hyperinflated lobe and limited space to carry out surgery. During the past two decades, conservative treatment options have increased for patients with mild and moderate disease. Read More

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December 2019

Early sonographic manifestation of fetal congenital lobar emphysema.

J Clin Ultrasound 2019 May 21;47(4):225-227. Epub 2018 Dec 21.

Department of Ob/Gyn, RAMBAM Health Care Campus, Haifa, Israel.

Advanced fetal sonographic equipment has contributed to the increase in prenatal diagnosis of congenital thoracic malformations. Among these anomalies is congenital lobar emphysema (CLE), a rare congenital anomaly characterized by over distention and overexpansion of the involved fetal pulmonary lobe. Several studies addressed the prenatal diagnosis of CLE in mid second or early third trimester. Read More

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Congenital Lobar Overinflation: A Rare Enigmatic Lung Lesion on Prenatal Ultrasound and Magnetic Resonance Imaging.

J Ultrasound Med 2019 May 12;38(5):1229-1239. Epub 2018 Sep 12.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Objectives: To report the ultrasound (US) features in prenatal cases of suspected congenital pulmonary airway malformation or unspecified lung lesions with a final surgical pathologic diagnosis of congenital lobar overinflation (CLO).

Methods: Institutional Review Board-approved radiology and clinical database searches from 2001 to 2017 were performed for prenatally diagnosed lung lesions with a final diagnosis of CLO. All patients had detailed US examinations in addition to magnetic resonance imaging (MRI). Read More

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Thoracoscopic Lobectomy for Congenital Lung Lesions.

Clin Perinatol 2017 12 28;44(4):781-794. Epub 2017 Sep 28.

Division of Pediatric Surgery, Department of Surgery, University of CA - San Francisco, 550 16th Street, 5th Floor, UCSF Box 0570, San Francisco, CA 94143, USA.

Congenital lung lesions (CLLs) comprise a heterogeneous group of developmental and histologic entities often diagnosed on screening prenatal ultrasound. Most fetuses with CLL are asymptomatic at birth; however, the risk of malignancy and infection drives the decision to prophylactically resect these lesions. The authors describe their approach to minimally invasive lobectomy in children with CLLs, postoperative care, and management of procedure-specific complications. Read More

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December 2017

Near Complete Obliteration of the Left Hemithorax by Congenital Lobar Emphysema in an Adult.

Ann Thorac Surg 2017 Nov;104(5):e367-e369

Department of Thoracic Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Congenital lobar emphysema is a rare pulmonary malformation typically diagnosed during infancy and is characterized by bullous disease. A 28-year-old woman, who presented with 1 week of progressive dyspnea and chest pain, was found to have left hemithoracic lung hyperinflation with perfusion deficit upon radiographic evaluation. Bullous disease was found intraoperatively to originate from 1 lower lobe segment. Read More

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November 2017

Conservative post-natal management of antenatally diagnosed congenital pulmonary airway malformations.

J Paediatr Child Health 2018 Mar 28;54(3):267-271. Epub 2017 Sep 28.

Monash Newborn, Monash Medical Centre Clayton, Melbourne, Victoria, Australia.

Aim: Management of congenital pulmonary airway malformations (CPAM) is controversial, especially for asymptomatic patients. We aim to describe the clinical manifestations and management of CPAM at a tertiary paediatric hospital using a retrospective audit.

Methods: Infants with CPAM were identified on the Fetal Diagnostic Unit database from 2007 to 2014. Read More

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Pulmonary interstitial glycogenosis associated with a spectrum of neonatal pulmonary disorders.

Hum Pathol 2017 10 2;68:154-165. Epub 2017 Sep 2.

Division of Diagnostic Imaging, The Hospital for Sick Children and University of Toronto, Toronto, Ontario M5T 1W7, Canada.

Primary or isolated pulmonary interstitial glycogenosis (PIG) is a rare disease presenting as tachypnea and hypoxemia during the perinatal period. A diffuse interstitial infiltrate with focal hyperinflation is visible on chest imaging. The biopsy findings include diffuse expansion of the interstitium by spindle-shaped cells with pale cytoplasm that, on electron microscopy (EM), are poorly differentiated mesenchymal cells containing abundant monoparticulate glycogen. Read More

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October 2017

Prenatal diagnosis of congenital lobar fluid overload.

Taiwan J Obstet Gynecol 2017 Aug;56(4):425-431

Department of Radiology, MacKay Memorial Hospital, Taipei, Taiwan; MacKay Medicine, Nursing and Management College, Taipei, Taiwan. Electronic address:

Prenatal congenital lobar fluid overload (CLFO), which was first described by Ramsay and Byron, is identical to postnatal congenital lobar overinflation. It is characterized by progressive lobar overexpansion that compresses the other adjacent lung lobes. The underlying cause can be an intrinsic cartilaginous abnormality or an extrinsic airway compression. Read More

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Case 1: Persistent Tachypnea in an Infant.

Pediatr Rev 2017 Jul;38(7):330-331

Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.

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Congenital lobar emphysema in a kitten.

J Small Anim Pract 2017 Nov 28;58(11):659-663. Epub 2017 Mar 28.

Faculty of Veterinary Medicine, Ghent University, B-9820 Merelbeke, Belgium.

A five-month-old ragdoll cat presented with severe respiratory signs, unresponsive to medical therapy. Hyperinflation of the right middle lung lobe was diagnosed with radiography and computed tomography. Lung lobectomy following a median sternotomy led to full recovery. Read More

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November 2017

Prenatal diagnosis, 3-D virtual rendering and lung sparing surgery by ligasure device in a baby with "CCAM and intralobar pulmonary sequestration".

Open Med (Wars) 2016 23;11(1):200-203. Epub 2016 Jun 23.

Division of Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy.

Congenital cystic lung lesions are a rare but clinically significant group of anomalies, including congenital cystic adenomatoid malformation (CCAM), pulmonary sequestration, congenital lobar emphysema (CLE) and bronchogenic cysts. Despite the knowledge of these lesions increasing in the last years, some aspects are still debated and controversial. The diagnosis is certainly one aspect which underwent many changes in the last 15 years due to the improvement of antenatal scan and the introduction of 3-D reconstruction techniques. Read More

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Bilateral congenital lobar emphysema: staged management.

J Pediatr Surg 2017 Sep 31;52(9):1442-1445. Epub 2017 Jan 31.

Division of Pediatric General, Thoracic and Fetal Surgery, Department of Surgery, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA. Electronic address:

Background: Only a few isolated cases in the literature exist to guide management of bilateral congenital lobar emphysema (CLE). Here, we review our experience in infants with bilateral CLE.

Methods: A case series of all infants presenting with bilateral CLE from 2014 to 2015 in a single institution. Read More

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September 2017

Imaging of congenital pulmonary malformations.

Acta Biomed 2016 07 28;87 Suppl 3:45-50. Epub 2016 Jul 28.

Department of Surgical Sciences, Section of Radiological Sciences, University of Parma, Parma Hospital, Parma, Italy.

Congenital pulmonary malformations represent a broad spectrum of anomalies that may result in varied clinical and pathologic pictures, ranging from recurrent pulmonary infections and acute respiratory distress syndrome, which require timely drug therapy, up to large space-occupying lesions needing surgical treatment. This classification includes three distinct anatomical and pathological entities, represented by Congenital Cystic Adenomatoid Malformation, Bronchopulmonary Sequestration and Congenital Lobar Emphysema. The final result in terms of embryological and fetal development of these alterations is a Congenital Lung Hypoplasia. Read More

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