32 results match your criteria Imaging in Classic Osteosarcoma

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A Time-lapse, Label-free, Quantitative Phase Imaging Study of Dormant and Active Human Cancer Cells.

J Vis Exp 2018 02 16(132). Epub 2018 Feb 16.

Vascular Biology Program, Boston Children's Hospital; Department of Surgery, Harvard Medical School and Boston Children's Hospital;

The acquisition of the angiogenic phenotype is an essential component of the escape from tumor dormancy. Although several classic in vitro assays (e.g. Read More

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http://dx.doi.org/10.3791/57035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931278PMC
February 2018
6 Reads

Malignant tumours of the foot and ankle.

EFORT Open Rev 2017 May 11;2(5):261-271. Epub 2017 May 11.

Laboratoire d'anatomie et cytologie pathologiques, Institut Universitaire du Cancer de Toulouse- Oncopole, 1 avenue Irène Joliot-Curie. 31059 Toulouse Cedex 9, France.

Most of tumours of the foot are tumour-like (synovial cyst, foreign body reactions and epidermal inclusion cyst) or benign conditions (tenosynovial giant cells tumours, planta fibromatosis). Malignant tumours of the soft-tissue and skeleton are very rare in the foot and their diagnosis is often delayed with referral to specialised teams after initial inappropriate procedures or unplanned excisions. The adverse effect of these misdiagnosed tumours is the increasing rate of amputation or local recurrences in the involved patients. Read More

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http://dx.doi.org/10.1302/2058-5241.2.160078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467685PMC
May 2017
8 Reads

Primary intracranial Ewing's sarcoma with unusual features.

Int J Clin Exp Pathol 2015 1;8(1):260-74. Epub 2015 Jan 1.

Department of Pathology, University of Oklahoma Health Sciences Center Oklahoma City, OK 73104, USA ; Department of Pathology, Oklahoma City Veterans Administration Medical Center Oklahoma City, OK 73104, USA.

Pediatric primary "small round blue cell" tumors in the CNS represent several entities, some more common than others. Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) is rare and must be distinguished from other tumors such as medulloblastoma [1, 2], atypical rhabdoid/teratoid tumor, ependymomal tumors, metastatic sarcomas, hematologic malignancies, and other mimics. Although therapy for ES/pPNET is effective, it brings severe side effects, including cardiac toxicity, making correct recognition important [3]. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348914PMC
December 2015
10 Reads

Sclerotic multiple myeloma with an unusual sunburst periosteal reaction occurring in the sternum.

Skeletal Radiol 2015 May 29;44(5):749-54. Epub 2014 Oct 29.

Department of Radiology, Third Hospital of Hebei Medical University, Hebei Province Biomechanical Key Laboratory of Orthopedics, 139 Ziqiang Road, Shijiazhuang City, 050051, Hebei Province, China,

Multiple myeloma is a disseminated neoplastic monoclonal gammopathy that usually affects the skull, clavicle, rib, pelvis, spinal column, and proximal portions of the humerus and femur. The initial manifestation of multiple myeloma in the sternum is rare. The classic radiological presentations of multiple myeloma are multiple "punched-out" areas of bone destruction, expansile lytic lesions, and generalized osteoporosis. Read More

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http://dx.doi.org/10.1007/s00256-014-2036-xDOI Listing
May 2015
11 Reads

Cavernous hemangioma of the frontal bone: a case report.

J Med Case Rep 2014 Apr 9;8:121. Epub 2014 Apr 9.

Department of Neurosurgery, San Salvatore City Hospital, via Vetoio, Coppito, L'Aquila 67100, Italy.

Introduction: Cavernous hemangiomas are rare benign bone tumors and those at the level of the cranial bones are even rarer.

Case Presentation: A 50-year-old woman of Italian ethnicity presented with a frontal mass. A computed tomography scan showed an osteolytic lesion and a magnetic resonance imaging scan revealed a hypointense lesion on the T1-weighted image and a hyperintense lesion on the T2-weighted image. Read More

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http://www.jmedicalcasereports.com/content/pdf/1752-1947-8-1
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http://www.jmedicalcasereports.com/content/8/1/121
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http://dx.doi.org/10.1186/1752-1947-8-121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000154PMC
April 2014
5 Reads

Osteosarcoma: review of the various types with emphasis on recent advancements in imaging.

Semin Musculoskelet Radiol 2013 Apr 14;17(2):123-36. Epub 2013 May 14.

Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA 22908, USA.

Osteosarcoma is the classic malignant osteoid-forming bone tumor. The typical clinical presentation, histology, imaging findings, treatment, and prognosis for each subtype of osteosarcoma is provided. Particular emphasis is placed on more current magnetic resonance imaging and nuclear medicine imaging techniques that may soon improve the ability to determine the most appropriate therapy and ultimately improve patient survival. Read More

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http://dx.doi.org/10.1055/s-0033-1342969DOI Listing
April 2013
2 Reads

Primary Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) of the penis: a report of an extraordinarily unusual site and a literature review of extraskeletal Ewing's sarcoma.

Int J Surg Pathol 2013 Feb 25;21(1):63-7. Epub 2012 Jul 25.

St Luke's-Roosevelt Hospital Center, New York, NY 10019, USA.

Ewing's sarcomas/primitive neuroectodermal tumors (ES/PNETs) arise from a multipotent progenitor cell and are considered to be of neuroectodermal derivation. Most tumors commonly arise in the skeletal system, which are the classic ES/PNET and occasionally occur in the soft tissue of extraskeletal sites, which are named extraskeletal Ewing's sarcomas (EES/PNET). This study reports a case of a 28-year-old man with primary EES/PNET of the penis. Read More

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http://dx.doi.org/10.1177/1066896912454565DOI Listing
February 2013
6 Reads

Localized extraosseous Ewing's sarcoma of the chest wall resected by video-assisted thoracoscopic surgery.

Gen Thorac Cardiovasc Surg 2010 Dec 18;58(12):647-50. Epub 2010 Dec 18.

Department of Surgery, Kagawa Prefectural Central Hospital, 5-4-16 Ban-cho, Takamatsu, Kagawa, 760-8557, Japan.

Extraosseous Ewing's sarcoma (ES) is a small round cell tumor arising in soft tissue that was undifferentiated histologically from classic ES of bone. It frequently affects children and adolescents, with an unfavorable prognosis. Herein, we report a case of localized extraosseous ES of the chest wall resected by video-assisted thoracoscopic surgery (VATS). Read More

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http://dx.doi.org/10.1007/s11748-009-0574-2DOI Listing
December 2010
2 Reads

Small cell osteosarcoma: cytopathologic characteristics and differential diagnosis.

Am J Clin Pathol 2010 May;133(5):756-61

Department of Pathology, The Johns Hopkins Hospital, 600 N Wolfe St, Path 406, Baltimore, MD 21287, USA.

Small cell osteosarcoma may present a challenging primary diagnosis on cytologic assessment owing to its rarity and its morphologic similarity to other small round blue cell tumors. Five cases of small cell osteosarcoma from our cytopathology archives were identified and reviewed and cytologic features elaborated. Three cases were fine-needle aspirations from bony lesions in the classic location for osteosarcoma (2 distal femur and 1 proximal tibia), and 2 aspirations were from metastases. Read More

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http://dx.doi.org/10.1309/AJCPO07VGDZCBRJFDOI Listing
May 2010
2 Reads

Osteosarcoma of the lumbar vertebra: case report and a review of the literature: rare localization with long survival.

Arch Orthop Trauma Surg 2009 Dec 14;129(12):1701-5. Epub 2009 May 14.

Department of Orthopaedic Surgery and Traumatology, Trakya University, 22030, Edirne, Turkey.

Classic osteosarcoma (OS) is a highly malignant sarcoma with the production of osteoid matrix. The most common sites of origin are the metaphyseal regions of the distal femur, proximal tibia, and proximal humerus, although the tumor can develop in any bone. Flat bone involvement is very rare (8%). Read More

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http://dx.doi.org/10.1007/s00402-009-0896-7DOI Listing
December 2009
6 Reads

Dedifferentiated chromophobe renal cell carcinoma with massive osteosarcoma-like divergent differentiation: a singular entity in the spectrum of retroperitoneal calcifying tumors.

Int J Surg Pathol 2010 Oct 18;18(5):419-23. Epub 2008 Dec 18.

Department of Clinical Sciences, University of Parma, Parma, Italy.

Sarcomatoid change in renal cell carcinoma is the result of the dedifferentiation of the "parent" tumor into a high-grade malignancy characterized by sarcoma-like features and associated with an accelerated clinical course and poorer prognosis. Any of the renal cell carcinoma subtypes can undergo sarcomatoid dedifferentiation, with the chromophobe variant being the most prone. The present report describes the case of a woman affected by a classic chromophobe renal cell carcinoma that developed dedifferentiation accompanied by a very rare osteosarcoma-like divergent differentiation, which constituted about 90% of the entire retroperitoneal mass. Read More

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http://ijs.sagepub.com/content/early/2008/12/18/106689690832
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http://ijs.sagepub.com/cgi/doi/10.1177/1066896908329414
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http://dx.doi.org/10.1177/1066896908329414DOI Listing
October 2010
8 Reads

Malignant tumours of the heart: a review of tumour type, diagnosis and therapy.

Clin Oncol (R Coll Radiol) 2007 Dec 10;19(10):748-56. Epub 2007 Aug 10.

Department of Surgery, University Hospitals of Cleveland, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA.

Primary cardiac neoplasms are rare and occur less commonly than metastatic disease of the heart. In this overview, current published studies concerning malignant neoplasms of the heart are reviewed, together with some insights into their aetiology, diagnosis and management. We searched medline using the subject 'cardiac neoplasms'. Read More

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http://dx.doi.org/10.1016/j.clon.2007.06.009DOI Listing
December 2007
2 Reads

Aggressive osteogenic desmoplastic melanoma: a case report.

J Cutan Pathol 2007 May;34(5):423-6

Department of Dermatopathology, Mount Sinai Medical Center, New York, NY, USA.

A case of an osteogenic desmoplastic melanoma occurring on the sole of the foot of a 60-year-old African American man is described. The tumor measured 4.8 cm in greatest dimension, invaded to a thickness of 2. Read More

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http://dx.doi.org/10.1111/j.1600-0560.2006.00634.xDOI Listing
May 2007
8 Reads

Osteosarcoma (osteogenic sarcoma).

Authors:
Piero Picci

Orphanet J Rare Dis 2007 Jan 23;2. Epub 2007 Jan 23.

Rizzoli Orthopaedic Institute, Scientific Institution for Research Hospitalization and Health Care, Bologna, Italy.

Osteosarcoma is a primary malignant tumour of the skeleton characterised by the direct formation of immature bone or osteoid tissue by the tumour cells. The classic osteosarcoma is a rare (0.2% of all malignant tumours) highly malignant tumour, with an estimated incidence of 3 cases/million population/year. Read More

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http://ojrd.biomedcentral.com/articles/10.1186/1750-1172-2-6
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http://dx.doi.org/10.1186/1750-1172-2-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794406PMC
January 2007
3 Reads

Radiology quiz case 2. Classic osteosarcoma of the temporal bone.

Arch Otolaryngol Head Neck Surg 2005 Oct;131(10):922, 926

Diyarbakir Military Hospital, Diyarbakir, Turkey.

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http://dx.doi.org/10.1001/archotol.131.10.922DOI Listing
October 2005
2 Reads

Ewing's sarcoma of the cavernous sinus: case report.

Neurosurgery 2005 Jun;56(6):E1375; discussion E1375

Department of Neurosurgery, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Objective And Importance: The Ewing's sarcoma (ES) family of tumors is a relatively rare entity, presenting most commonly in children. While the most common sites for this group of tumors are the trunk and the extremities, this case is unique in that we describe a long-term follow-up with an ES presenting in the cavernous sinus.

Clinical Presentation: We report the case of a 13-year-old girl presenting with the symptoms of classic orbital apex syndrome. Read More

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June 2005
2 Reads

Radiographic features of Ewing's sarcoma of the bones of the hands and feet.

Skeletal Radiol 2001 Mar;30(3):121-6

Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

The radiographic features of Ewing's sarcoma of the bones of the hands and feet are reviewed utilizing cases obtained from the Mayo Clinic patient files and the consultation files of Drs. D.C. Read More

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March 2001
2 Reads

Juxtacortical osteosarcoma. A distinct malignant bone neoplasm.

Adv Clin Path 2000 Jul;4(3):127-31

Anatomy Department, Faculty of Health and Caring Professions, Technological Educational Institution, Athens. Greece.

The purpose of this report is the study of a malignant bone tumor of similar histological picture with conventional (intramedullary) osteosarcoma. Contributing factors in the study of juxtacortical osteosarcoma are the clinical, X-ray and histologic pictures. A case of parosteal osteosarcoma in a 28-year-old male is reported. Read More

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July 2000
3 Reads

[Primary chemotherapy with the Rosen T10 protocol before conservative surgery in limb primitive osteosarcomas: results about 56 cases].

Bull Cancer 2000 Feb;87(2):183-8

Institut Salah Azaïz, Tunis, Tunisie.

We report the results of a prospective Tunisian study using primary chemotherapy followed by conservative surgery in primitive limb osteosarcoma. From January 1988 to January 1998, 56 patients affected by limb osteosarcoma entered in a prospective study of neoadjuvant chemotherapy with the T10 protocol before surgery with a conservative intent. Initial work-up include: clinical exam with tumor measurements, chest and limb X-rays, limb CT-scan or MRI, chest CT-scan, bone scintigraphy and hematological and renal biological exams. Read More

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February 2000
4 Reads

Malignant tumors of the osteogenic matrix.

Eur J Radiol 1998 May;27 Suppl 1:S98-109

Institute of Radiology of the University of Modena, Policlinico, Italy.

This article focuses on major clinical and imaging features that are of practical interest in the diagnosis and management of osteosarcoma, a malignant tumor arising from the osteogenic matrix. The current histologic classification of this tumor is also reported. Different types of osteosarcoma are described, each of them with a definite clinical and radiographic pattern. Read More

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May 1998
3 Reads

Multifocal osteosarcoma in a patient with Fanconi anemia.

J Pediatr Hematol Oncol 1997 May-Jun;19(3):251-3

Oregon Health Sciences University, Portland, USA.

Purpose: The purpose of this report is to present a case of multifocal osteosarcoma in a patient with Fanconi anemia.

Patients And Methods: A nine year old girl with known Fanconi anemia presented with a pathologic femur fracture. Imaging studies confirmed soft tissue and bony involvement in the femur, ipsilateral tibia, and possibly contralateral femur. Read More

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July 1997
1 Read

Zygomatic osteoma with atypical heterogeneity in a dog.

J Comp Pathol 1996 Feb;114(2):199-203

Department of Surgical Sciences, University of Wisconsin-Madison, USA.

An osteoma of the zygomatic bone in a young dog is described. It had large, centralized radiolucent regions consisting of fatty bone marrow and sparse trabeculae. A discrete, proliferative nodule within the osteoma consisted of closely-packed woven bone trabeculae and pleomorphic osteoblasts associated with haphazard osteoid deposits, resembling osteosarcoma-like change. Read More

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February 1996
1 Read

Calcification as a sign of sarcomatous degeneration of malignant pleural mesotheliomas: a new CT finding.

J Comput Assist Tomogr 1996 Jan-Feb;20(1):42-4

Department of Radiology, George Washington University Medical Center, Washington, D.C. 20037, USA.

We present two cases demonstrating, on CT examination, heavily calcified mass lesions associated with malignant pleural mesothelioma in workers occupationally exposed to asbestos. These masses proved to be osteogenic sarcomatous degeneration within mesotheliomas. The observation of dense calcification within a pleural mass should raise a suspicion of osteosarcomatous degeneration if it is seen in conjunction with other classic signs of malignant pleural mesothelioma. Read More

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March 1996
2 Reads

Multicentric osteosarcoma. Report of 5 cases.

Chir Organi Mov 1991 Apr-Jun;76(2):113-22

Centro Tumori dell'Apparato Locomotore, Istituto Ortopedico Rizzoli, Bologna.

Multiple foci of osteosarcoma are found in several pathological conditions: skip metastases, late bone metastases from osteosarcoma, so called metachronous osteosarcoma and multicentric osteosarcoma. The authors describe five cases with multicentric osteosarcoma of the skeleton. These lesions differ from classic osteosarcoma for their clinical and radiographical features. Read More

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February 1992
3 Reads

Osteosarcoma with isolated metastases to the pleura.

Pediatr Radiol 1991 ;21(3):226

Department of Radiology, Tripler Army Medical Center, Honolulu, Hawaii 96859.

Osteosarcoma is the most common primary skeletal malignancy of childhood, typically occurring between the ages of 10 and 20. The classic radiographic appearance is that of a mixed lytic and sclerotic lesion originating in the metaphysis of the long bones with cortical destruction, periostitis, and an associated soft tissue mass. Metastatic disease to the lungs is an important prognostic indicator and is found in the majority of patients dying of the disease. Read More

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July 1991
2 Reads

Bone metastases from Ewing's sarcoma radiologically recapitulate the features of a primary Ewing's tumour.

Authors:
P N Plowman

Clin Radiol 1989 Sep;40(5):498-500

Department of Radiotherapy, St Bartholomew's Hospital, London.

It is rare that the radiological appearances of secondary deposits in bone suggest the primary tumour. The X-ray appearances of bone metastases in three patients with Ewing's sarcoma resembled the classic radiographic appearances of the primary bone tumour and are here described. Read More

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September 1989
1 Read

Extraskeletal osteosarcoma in two dogs.

J Am Vet Med Assoc 1989 May;194(10):1452-6

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824-1314.

Extraskeletal osteosarcoma (ESOS) of the spleen and jejunum was diagnosed in 2 dogs. As an extremely uncommon type of tumor that has proven difficult to treat, ESOS is associated with high rate of local recurrence and metastatic disease. Extraskeletal osteosarcoma principally affects older dogs, has no apparent breed predilection, and may develop more frequently in males. Read More

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May 1989
3 Reads

Radiographic appearance of Ewing sarcoma of the hands and feet: report from the Intergroup Ewing Sarcoma Study.

AJR Am J Roentgenol 1985 Feb;144(2):331-6

Review of current data from the Intergroup Ewing Sarcoma Study (IESS) shows that Ewing sarcoma is rare in bones of the hands and feet. The 12 patients from the IESS protocols with hand or foot Ewing sarcoma are comparable to those already reported in the literature. With the exception of lesions in the calcaneus, the prognosis for disease-free survival is excellent. Read More

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http://dx.doi.org/10.2214/ajr.144.2.331DOI Listing
February 1985
2 Reads

Osteosarcoma arising in heterotopic ossification of dermatomyositis: case report and review of the literature.

Cancer 1981 Sep;48(5):1256-61

A patient with dermatomyositis developed malignant transformation of the benign interfascial heterotopic bone. This patient had classic childhood dermatomyositis at the age of 3 years, and the disease was arrested after a one-year course of corticosteroid therapy. Extensive subcutaneous calcinosis cutis and deep interfascial calcinosis were the residua of the disease. Read More

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September 1981
2 Reads

Management of osteogenic sarcoma: a perspective based on the Mayo Clinic experience.

Natl Cancer Inst Monogr 1981 Apr(56):193-9

We reviewed pertinent aspects of the Mayo Clinic experience with osteogenic sarcoma to place into perspective some of the recent advances in the management of patients with this tumor. Various histopathologic subtypes have been recognized and can be differentiated from the conventional or classic osteogenic sarcoma. Our experience indicated that, when appropriate, crossbone amputation provided adequate and effective surgical treatment. Read More

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April 1981
3 Reads

A clinicopathologic study of 20 cases of large-cell (atypical) Ewing's sarcoma of bone.

Am J Surg Pathol 1980 Feb;4(1):29-36

A review of 347 Ewing's tumors that were seen at the Mayo Clinic during the period to the end of 1978 revealed 20 that differed histologically from the remainder. These 20--called "large-cell Ewing's tumor"--differed from the classic Ewing tumor in having larger, more pleomorphic cells, often with conspicuous nucleoli. More males than females had such tumors, and most patients were in the second decade of life. Read More

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February 1980
4 Reads
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