2,064 results match your criteria Imaging in Chiari I Malformation


Investigation of the Neuropathic Pain Caused by Syringomyelia Associated with Chiari I Malformation.

Asian Spine J 2019 Apr 2. Epub 2019 Apr 2.

Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Study Design: Retrospective cohort study.

Purpose: To investigate the correlation between the syrinx morphology and neuropathic pain caused by syringomyelia associated with Chiari I malformation.

Overview Of Literature: Neuropathic pain caused by syringomyelia is refractory and markedly impairs the patient. Read More

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http://asianspinejournal.org/journal/view.php?doi=10.31616/a
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http://dx.doi.org/10.31616/asj.2018.0242DOI Listing
April 2019
3 Reads

Chiari malformations: principles of diagnosis and management.

BMJ 2019 Apr 8;365:l1159. Epub 2019 Apr 8.

Department of Paediatric Neurosurgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1136/bmj.l1159DOI Listing

Headache in Chiari Malformation.

Neuroimaging Clin N Am 2019 May 20;29(2):243-253. Epub 2019 Feb 20.

Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02215, USA. Electronic address:

Headache is a common symptom in patients with Chiari I malformation (CMI), characterized by 5 mm or greater cerebellar tonsillar herniation below foramen magnum. Radiologists should be aware of the different types of headaches reported by CMI patients and which headache patterns are distinctive features of the diagnosis. A methodical imaging strategy is required to fully assess a CMI patient to exclude secondary causes of tonsillar herniation such as intracranial hypotension or associated conditions such as syrinx. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10525149193000
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http://dx.doi.org/10.1016/j.nic.2019.01.005DOI Listing
May 2019
2 Reads

Epicrania Fugax as the presenting symptom of a cerebellar abscess.

Cephalalgia 2019 Mar 20:333102419839793. Epub 2019 Mar 20.

1 Headache Unit, University Hospital of Valladolid, Valladolid, Spain.

Background: Epicrania fugax is included in the appendix of the International Classification of Headache Disorders and is characterized as recurrent brief attacks of linear or zigzag pain moving across the cranial surface, commencing and terminating in the distribution of different nerves. We present a new case of epicrania fugax in which the headache was the presenting symptom of a cerebellar abscess.

Case Report: We present a 58-year-old woman with prior history of Chiari I malformation who underwent suboccipital craniectomy. Read More

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http://dx.doi.org/10.1177/0333102419839793DOI Listing
March 2019
4 Reads

Atypical Presentation of Chiari I Malformation in a 13-Year-Old Adolescent.

Pediatr Emerg Care 2019 Apr;35(4):e72-e75

Department of Neurosurgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

In this report, we describe a 13-year-old with opisthotonos as the presenting symptom of Chiari I malformation. This presentation is rare and has previously been reported only in infants. We describe the physical and radiologic findings, literature regarding Chiari malformation, and differential diagnosis of opisthotonos in this patient. Read More

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http://dx.doi.org/10.1097/PEC.0000000000001801DOI Listing

Surgical Experience in Pediatric Patients with Chiari-I Malformations Aged ≤18 Years.

J Neurosci Rural Pract 2019 Jan-Mar;10(1):85-88

Department of Neurosurgery, Maharaja Agrasen Hospital, New Delhi, India.

Objective: The objective of this study was to retrospectively study Chiari I malformation patients (<18 years) treated surgically.

Materials And Methods: Chiari I malformation patients (<18 years) treated surgically at our institute were retrospectively studied.

Results: During the study period between January 1999 and June 2011, fifty patients, aged ≤18 years with Chiari malformation, were treated surgically and formed the basis for this series. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_160_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337998PMC
February 2019
1 Read

Development of Common Data Elements for Use in Chiari Malformation Type I Clinical Research: An NIH/NINDS Project.

Neurosurgery 2019 Jan 23. Epub 2019 Jan 23.

Division of Neuroscience, National Institutes of Health/National Institute of Neurological Disorders and Stroke, Bethesda, Maryland.

The management of Chiari I malformation (CMI) is controversial because treatment methods vary and treatment decisions rest on incomplete understanding of its complex symptom patterns, etiologies, and natural history. Validity of studies that attempt to compare treatment of CMI has been limited because of variable terminology and methods used to describe study subjects. The goal of this project was to standardize terminology and methods by developing a comprehensive set of Common Data Elements (CDEs), data definitions, case report forms (CRFs), and outcome measure recommendations for use in CMI clinical research, as part of the CDE project at the National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health. Read More

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http://dx.doi.org/10.1093/neuros/nyy475DOI Listing
January 2019
5 Reads
3.620 Impact Factor

[Correlation between syrinx resolution after posterior fossa decompression and cervical sagittal profile change in adolescents with Chiari malformation and syringomyelia].

Zhonghua Yi Xue Za Zhi 2019 Jan;99(3):183-187

Department of Spinal Surgery, Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing 210008, China.

To evaluate the long term change of the cervical sagittal profile in adolescent Chiari malformation type Ⅰ (CMI)/syringomyelia undergoing posterior fossa decompression (PFD) and to further evaluate the correlation between the syrinx resolution and cervical sagittal profile. A retrospective radiographic study was performed in 32 adolescents undergoing PFD for CMI/syringomyelia from October 2011 to August 2015 with a minimum 2-year follow-up. There were 23 males and 9 females, with a mean age of (13. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.03.006DOI Listing
January 2019
1 Read

Comparison of Dural Splitting and Duraplasty in Patients with Chiari Type I Malformation: Relationship between Tonsillo-Dural Distance and Syrinx Cavity.

Turk Neurosurg 2019 ;29(2):229-236

Mustafa Kemal University, School of Medicine, Department of Neurosurgery, Hatay, Turkey.

Aim: To compare the clinical and radiological results of dural splitting and duraplasty in patients with Chiari Type I Malformation.

Material And Methods: This study includes 113 adult patients with Chiari Type I malformation treated between 2009 and 2013. The patients were divided into two groups according to the surgical method (Group 1: dural splitting, Group 2: duraplasty). Read More

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http://dx.doi.org/10.5137/1019-5149.JTN.23319-18.2DOI Listing

Kyphoscoliosis with Klippel-Trenaunay syndrome: a case report and literature review.

BMC Musculoskelet Disord 2019 Jan 5;20(1):10. Epub 2019 Jan 5.

Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China.

Background: Klippel-Trenaunay syndrome (KTS) is a rare congenital syndrome characterized by the triad of venous varicosities, capillary malformations and limb hypertrophy. However, KTS may rarely occur in combination with kyphoscoliosis.

Case Presentation: We presented an 18-year-old female with KTS and kyphoscoliosis. Read More

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https://bmcmusculoskeletdisord.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12891-018-2393-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320630PMC
January 2019
17 Reads

Patients with "benign" Chiari I malformations require surgical decompression at a low rate.

J Neurosurg Pediatr 2019 01 4:1-9. Epub 2019 Jan 4.

1Department of Neurosurgery and Division of Pediatric Neurosurgery, University of Alabama at Birmingham, Alabama; and.

OBJECTIVE There are sparse published data on the natural history of “benign” Chiari I malformation (CM-I)—i.e., Chiari with minimal or no symptoms at presentation and no imaging evidence of syrinx, hydrocephalus, or spinal cord signal abnormality. Read More

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http://dx.doi.org/10.3171/2018.10.PEDS18407DOI Listing
January 2019
5 Reads

Cerebellar tonsil ectopia measurement in type I Chiari malformation patients show poor inter-operator reliability.

Fluids Barriers CNS 2018 Dec 17;15(1):33. Epub 2018 Dec 17.

Department of Biological Engineering, University of Idaho, 875 Perimeter Drive MS 0904, Moscow, ID, 83844-0904, USA.

Background: Type 1 Chiari malformation (CM-I) has been historically defined by cerebellar tonsillar position (TP) greater than 3-5 mm below the foramen magnum (FM). Often, the radiographic findings are highly variable, which may influence the clinical course and patient outcome. In this study, we evaluate the inter-operator reliability (reproducibility) of MRI-based measurement of TP in CM-I patients and healthy controls. Read More

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http://dx.doi.org/10.1186/s12987-018-0118-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296028PMC
December 2018
4 Reads

Dynamic Cerebellar Tonsils in Chiari Malformation.

J Pediatr 2019 Mar 7;206:295. Epub 2018 Dec 7.

College of Medicine Medical University of South Carolina Charleston, South Carolina.

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http://dx.doi.org/10.1016/j.jpeds.2018.11.020DOI Listing

Choosing Wisely Canada: Pediatric Neurosurgery Recommendations.

Paediatr Child Health 2018 Sep 1;23(6):383-387. Epub 2018 Mar 1.

Division of Neurosurgery, Hospital For Sick Children, Toronto, Ontario.

Objectives: Choosing Wisely Canada is an evidence-based, patient-focused, physician-led campaign to improve the delivery of medical care in Canada. The goal of this study was to produce Canadian recommendations for physicians treating patients with selected paediatric neurosurgery issues.

Methods: Paediatric neurosurgeons practicing in Canada were invited to participate. Read More

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https://academic.oup.com/pch/article/23/6/383/4916924
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http://dx.doi.org/10.1093/pch/pxy012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234424PMC
September 2018
16 Reads

[Cervico-occipital junction malformation and vitiligo].

Pan Afr Med J 2018 20;30:146. Epub 2018 Jun 20.

Departement of Dermatology, Military Hospital My Ismail, Meknes, Morocco.

Vitiligo is a relatively common multifactorial polygenetic dermatosis (0.5%-2% of general population) characterized by segmental or nonsegmental cutaneous depigmentation. Chiari malformation is a congenital cervico-occipital junction disease characterized by a migration of a part of the cerebellum through the foramen magnum. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.146.15610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201618PMC
November 2018
5 Reads

High Incidence of Cranial Synostosis and Chiari I Malformation in Children With X-Linked Hypophosphatemic Rickets (XLHR).

J Bone Miner Res 2019 Mar 20;34(3):490-496. Epub 2018 Nov 20.

Pediatric Neurosurgery, Hôpital Femme Mère Enfant, Hospices Civiles de Lyon and University Claude Bernard Lyon 1, Bron Cedex, France.

X-linked hypophosphatemic rickets (XLHR) represents the most common form of genetic hypophosphatemia and causes rickets and osteomalacia in children because of increased FGF23 secretion and renal phosphate wasting. Even though cranial vault and craniovertebral anomalies of potential neurosurgical interest, namely early closure of the cranial sutures and Chiari type I malformation, have been observed in children with XLHR, their actual incidence and characteristics are not established. The aims of this study were to analyze the incidence of cranial and cervico-occipital junction (COJ) anomalies in children with XLHR and describe its features. Read More

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http://dx.doi.org/10.1002/jbmr.3614DOI Listing
March 2019
21 Reads

Clinical Significance of Variable Clivus Gradients in Patients with Chiari Malformation Type I After Surgical Decompression: A Retrospective Analysis.

World Neurosurg 2019 Feb 19;122:e443-e448. Epub 2018 Oct 19.

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:

Objective: Previous studies have shown that the clivus angle gradient is significantly decreased in patients with Chiari malformation type I (CMI) with an associated syrinx compared with patients with CMI only and a healthy population. To date, the relationship between the clivus gradient and clinical outcomes has remained unclear. The objective of the present study was to investigate whether different clivus gradients (∠α) in CMI after posterior fossa decompression will lead to different clinical outcomes. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.10.068DOI Listing
February 2019
32 Reads

Minimally-invasive approach to posterior fossa decompression: Initial experience in Adult Chiari Type 1 Malformation patients.

J Clin Neurosci 2018 Oct 4;56:90-94. Epub 2018 Jul 4.

Division of Neurosurgery, National University Health System, 1E Kent Ridge Road, 119228, Singapore; Department of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin, 750 Highland Avenue, 53726 Madison, WI, USA.

We report our initial experience using Minimally-Invasive Surgery (MIS) technique for Posterior Fossa Decompression (PFD) in Adult Chiari 1 Malformation (C1M) patients. Five subjects who were treated with MIS PFD at our center and followed up over a 5-year period. Another nine subjects who were treated with Open PFD and follow up over the same period were used for comparison. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.06.054DOI Listing
October 2018

Familial Chiari Type 1: A Molecular Karyotyping Study in a Turkish Family and Review of the Literature.

World Neurosurg 2019 Jan 11;121:e852-e857. Epub 2018 Oct 11.

Department of Neurological Surgery, TR University of Health Sciences, Istanbul Fatih Sultan Mehmet Education and Research Hospital, Istanbul, Turkey.

Background: The etiology of Chiari I malformation (CMI) has not been fully elucidated. Therefore, we performed a genetic study of a Turkish family in which 3 sisters had a diagnosis of CMI with or without syringomyelia.

Methods: In a family with 7 children, 4 daughters complained of occipital headaches. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.235DOI Listing
January 2019
2 Reads

Chiari 1 Malformation Surgery: Comparing Non-violation of the Arachnoid versus Arachnoid Opening and Thermocoagulation of the Tonsils.

World Neurosurg 2019 Jan 4;121:e605-e613. Epub 2018 Oct 4.

Department of Anatomy, Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.

Objective: Evidence is lacking concerning the myriad surgical techniques for type 1 Chiari malformation. This study evaluated the impact of arachnoid violation with tonsil thermocoagulation during surgical craniovertebral junction decompression.

Methods: The evaluation included aspects of the neurologic examination and parameters of cerebrospinal fluid flow on magnetic resonance imaging during preoperative and postoperative periods. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183223
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http://dx.doi.org/10.1016/j.wneu.2018.09.175DOI Listing
January 2019
3 Reads

Response of Syrinx Associated with Chiari I Malformation to Posterior Fossa Decompression with or without Duraplasty and Correlation with Functional Outcome: A Prospective Study of 22 Patients.

J Neurosci Rural Pract 2018 Oct-Dec;9(4):587-592

Department of Neuroimaging and Interventional Neuroradiology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Background: The aim of the study is to correlate the surgical outcome with radiological changes in patients with Chiari I malformation (CMI) with syrinx. We also compared long-term functional and radiographic outcome in CM1 patients treated with posterior fossa decompression (PFD) with or without duroplasty.

Patients And Methods: From December 2013 to October 2015, 22 patients who underwent surgery with the diagnosis of CMI and syrinx were included in the study. Read More

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http://www.ruralneuropractice.com/text.asp?2018/9/4/587/2398
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http://dx.doi.org/10.4103/jnrp.jnrp_10_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126299PMC
October 2018
6 Reads

Imaging of Clival Hypoplasia in CHARGE Syndrome and Hypothesis for Development: A Case-Control Study.

AJNR Am J Neuroradiol 2018 Oct 20;39(10):1938-1942. Epub 2018 Sep 20.

Radiology (L.C.M.), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Background And Purpose: We present the largest case series to date on basiocciput abnormalities in CHARGE syndrome (Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary abnormalities, and Ear abnormalities and/or deafness). We aimed to show that basiocciput abnormalities are common and may aid in diagnosis. We furthermore explored whether clivus size correlates with the type of chromodomain-helicase-DNA binding protein 7 gene () mutation, which causes CHARGE syndrome, and with clinical criteria according to Blake et al and Verloes. Read More

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http://dx.doi.org/10.3174/ajnr.A5810DOI Listing
October 2018
23 Reads

Use of ventilation bag for the respiratory support during magnetic resonance imaging in Arnold-Chiari ventilated patients, a case report.

J Spinal Cord Med 2018 Sep 12:1-4. Epub 2018 Sep 12.

a Neurorehabilitation Department , Fondazione Ospedale San Camillo IRCCS , Venezia , Italia.

Context: Magnetic Resonance Imaging (MRI) is an essential diagnostic tool for neuroimaging tissues such as the spinal cord. Unfortunately, the use of MRI may be limited in ventilated patients, who cannot maintain the supine position in spontaneous breathing for the whole duration of the exam (i.e. Read More

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http://dx.doi.org/10.1080/10790268.2018.1519997DOI Listing
September 2018
3 Reads

Cerebellar Tonsillar Cysts Associated with Chiari Malformation in Adults: A Short Series.

World Neurosurg 2018 Dec 31;120:205-210. Epub 2018 Aug 31.

Post-graduation in Neuropsychiatry, Federal University of Pernambuco, Recife, Pernambuco, Brazil; Department of Neurosurgery, Federal University of Pernambuco, Recife, Pernambuco, Brazil.

Background: Authors analyzed surgical patients with Chiari malformation (CM) associated with cerebellar tonsillar cyst. This association is quite rarely encountered in the literature.

Case Description: We retrospectively reviewed 60 surgical adult patients with MRI evaluation who underwent posterior fossa decompression for treatment of CM type I. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183194
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http://dx.doi.org/10.1016/j.wneu.2018.08.165DOI Listing
December 2018
11 Reads

Fluid dynamics in syringomyelia cavities: Effects of heart rate, CSF velocity, CSF velocity waveform and craniovertebral decompression.

Neuroradiol J 2018 Oct 17;31(5):482-489. Epub 2018 Aug 17.

2 Department of Radiology, University of Wisconsin, USA.

Purpose How fluid moves during the cardiac cycle within a syrinx may affect its development. We measured syrinx fluid velocities before and after craniovertebral decompression in a patient and simulated syrinx fluid velocities for different heart rates, syrinx sizes and cerebrospinal fluid (CSF) flow velocities in a model of syringomyelia. Materials and methods With phase-contrast magnetic resonance we measured CSF and syrinx fluid velocities in a Chiari patient before and after craniovertebral decompression. Read More

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http://dx.doi.org/10.1177/1971400918795482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136130PMC
October 2018
16 Reads

Morphogenesis of Canine Chiari Malformation and Secondary Syringomyelia: Disorders of Cerebrospinal Fluid Circulation.

Front Vet Sci 2018 27;5:171. Epub 2018 Jul 27.

Department of Veterinary Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.

Chiari-like Malformation (CM) and secondary syringomyelia (SM), as well as their analogous human conditions, is a complex developmental condition associated with pain and accompanying welfare concerns. CM/SM is diagnosed ever more frequently, thanks in part to the increased availability of magnetic resonance imaging in veterinary medicine. Research over the last two decades has focused primarily on its pathophysiology relating to overcrowding of the cranial caudal fossa. Read More

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http://dx.doi.org/10.3389/fvets.2018.00171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074093PMC
July 2018
2 Reads

Clinical Characteristics, Imaging Findings and Surgical Outcomes of Chiari Malformation Type I in Pediatric and Adult Patients.

Curr Med Sci 2018 Apr 30;38(2):289-295. Epub 2018 Apr 30.

Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

A growing number of children and adolescents are being diagnosed as Chiari malformation type I (CM-I) for behavioral disorders, developmental delay, seizures, or abnormal orpharyngeal function. The aim of this study was to compare the clinical characteristics, imaging findings and surgical outcomes of CM-I in pediatric and adult patients. Between January 2014 and June 2017, 84 patients with CM-I underwent surgical treatment in our department. Read More

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http://dx.doi.org/10.1007/s11596-018-1877-2DOI Listing
April 2018
3 Reads

Synchronous Chiari III Malformation and Polydactyly.

World Neurosurg 2018 Oct 27;118:301-303. Epub 2018 Jul 27.

National Neuroscience Institute, Department of Neurosurgery, National Neuroscience Institute, Singapore. Electronic address:

Background: Chiari III malformation is an extremely rare congenital anomaly. At present, its primary and associated pathognomonic factors remain poorly understood. The authors report a case of a male neonate born with an occipital encephalocoele with herniation of posterior fossa contents associated with bilateral postaxial polydactyly. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.155DOI Listing
October 2018
26 Reads

Management of hydrocephalus and subdural hygromas in pediatric patients after decompression of Chiari malformation type I: case series and review of the literature.

J Neurosurg Pediatr 2018 Oct 20;22(4):426-438. Epub 2018 Jul 20.

Department of Neurosurgery, Johns Hopkins All Children's Institute for Brain Protection Sciences, St. Petersburg.

Objective: Hydrocephalus associated with subdural hygromas is a rare complication after decompression of Chiari malformation type I (CM-I). There is no consensus for management of this complication. The authors present a series of 5 pediatric patients who underwent CM-I decompression with placement of a dural graft complicated by posterior fossa hygromas and hydrocephalus that were successfully managed nonoperatively. Read More

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http://dx.doi.org/10.3171/2018.4.PEDS17622DOI Listing
October 2018
2 Reads

Intractable Hiccups Associated with Chiari Type I Malformation: Case Report and Literature Review.

World Neurosurg 2018 Oct 17;118:329-331. Epub 2018 Jul 17.

Department of Neurosurgery, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital, Shanghai, China.

Background: The authors report the case of a 34-year-old man who presented with intractable hiccups. The imaging examination showed that the patient was suffering from syringomyelia associated with Chiari type I malformation.

Case Descriptions: The patient underwent posterior fossa decompression combined with bilateral tonsillectomy and duroplasty. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183154
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http://dx.doi.org/10.1016/j.wneu.2018.07.065DOI Listing
October 2018
8 Reads

Neuroendoscopic Management of Coexisting Congenital Agenesis of Bilateral Foramen of Monro with Aqueductal Stenosis and Chiari Malformation: Case Report and Review of the Literature.

World Neurosurg 2018 Oct 11;118:55-58. Epub 2018 Jul 11.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.

Background: Bilateral occlusion of the foramen of Monro with aqueductal stenosis is a rare entity. Only 1 previous case has been reported in the literature.

Case Description: We present a 25-year-old female who presented with chronic headache of 7 years duration. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.016DOI Listing
October 2018
2 Reads

Interval Recovery of Syringomyelia in Chiari I Malformation Patient with Acute Cervical Trauma After Anterior Decompression: Case Report and Review of Literature.

World Neurosurg 2018 Oct 6;118:240-242. Epub 2018 Jul 6.

Neurosurgery Section, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico, USA.

Background: Syringomyelia in the cervical spinal cord is a complex pathology that is commonly associated with Chiari I malformation or spinal cord trauma. In both cases the development of syringomyelia has been linked to multiple anatomic and molecular elements including epidural compression. Literature has mainly reported posterior cervical decompressive procedures or shunting of the cyst as options to address this pathology. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183144
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http://dx.doi.org/10.1016/j.wneu.2018.06.229DOI Listing
October 2018
3 Reads

An Exceptional Neurosurgical Presentation of a Patient with Osteopetrosis.

World Neurosurg 2018 Nov 20;119:25-29. Epub 2018 Jun 20.

Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul University, Istanbul, Turkey. Electronic address:

Background: Osteopetrosis (OP) is a varied clinical condition caused by malfunction or insufficient development of osteoclasts, or both. Neurologic findings can occur because of osteopetrotic conditions restricting neural foramina through which the spinal cord, cranial nerves, or major vascular structures traverse the skull. Renal tubular acidosis (RTA) is a well-documented condition with OP. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.081DOI Listing
November 2018
12 Reads

Comparison of Dural Peeling versus Duraplasty for Surgical Treatment of Chiari Type I Malformation: Results and Complications in a Monocentric Patients' Cohort.

World Neurosurg 2018 Sep 19;117:e595-e602. Epub 2018 Jun 19.

Department of Neurosurgery, St-Luc Hospital, Université Catholique de Louvain, Brussels, Belgium. Electronic address:

Objective: Chiari malformation type I is typified by the downward herniation of the cerebellar tonsils through the foramen magnum, which can impede cerebrospinal fluid circulation and may lead to syringomyelia. The usual symptoms of this condition are neck pain and posterior headaches on Valsalva maneuver. Different surgical procedures have been described for cranio-cervical decompression (CCD), without a consensus being reached about the best suited technique. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.093DOI Listing
September 2018
6 Reads

Congenital aqueduct stenosis: Progressive brain findings in utero to birth in the presence of severe hydrocephalus.

Prenat Diagn 2018 08 5;38(9):706-712. Epub 2018 Jul 5.

Department of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Purpose: To evaluate the effects of progressive hydrocephalus on the developing brain in a cohort of fetuses diagnosed with congenital aqueduct stenosis by comparing prenatal magnetic resonance imaging and postnatal imaging.

Methods: This IRB approved single center retrospective review of prenatally diagnosed children with congenital aqueduct stenosis interrogated changes in the brain between prenatal and postnatal imaging and analyzed statistics using SAS software package version 9.3. Read More

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http://dx.doi.org/10.1002/pd.5317DOI Listing
August 2018
11 Reads

Chiari Headache.

Curr Pain Headache Rep 2018 Jun 14;22(7):49. Epub 2018 Jun 14.

Department of Neurology, Yale School of Medicine, New Haven, USA.

Purpose Of Review: Chiari malformations (CM) are a group of neuroanatomical pathologies resulting from overcrowding of the hindbrain. The purpose of this review is to characterize Chiari headache (CH) and describe diagnosis and treatment of the condition.

Recent Findings: Recent research has helped solidify the criteria for diagnosis of CH. Read More

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http://link.springer.com/10.1007/s11916-018-0702-8
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http://dx.doi.org/10.1007/s11916-018-0702-8DOI Listing
June 2018
17 Reads

Type I Chiari Malformation Presenting in an Adult.

BMJ Case Rep 2018 Jun 12;2018. Epub 2018 Jun 12.

Internal Medicine, Texas Tech University Health Science Center at the Permian Basin, Odessa, Texas, USA.

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http://dx.doi.org/10.1136/bcr-2018-224889DOI Listing
June 2018
3 Reads

Chiari 1 deformity in children: etiopathogenesis and radiologic diagnosis.

Handb Clin Neurol 2018 ;155:25-48

Division of Pediatric Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, United States.

The metamerically associated normal hindbrain and normal posterior fossa are programmed to grow together in such a way that the tonsils are located above the foramen magnum and surrounded by the cerebrospinal fluid (CSF) of the cisterna magna. This allows the pulsating CSF to move freely up and down across the craniovertebral junction (CVJ). A developmental mismatch between the rates of growth of the neural tissue and of the bony posterior fossa may result in the cerebellar tonsils being dislocated across the foramen magnum. Read More

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http://dx.doi.org/10.1016/B978-0-444-64189-2.00002-0DOI Listing
October 2018
2 Reads

Basilar Invagination: A Craniocervical Kyphosis.

World Neurosurg 2018 Sep 7;117:e180-e186. Epub 2018 Jun 7.

Post-graduation Program, Hospital do Servidor Público Estadual, São Paulo, Brazil.

Background: For more than a century, odontoid process prolapse, which compresses cranial base structures, has been the hallmark of basilar invagination (BI). The angulation of the whole skull toward the cervical spine may be considered to contribute to BI and odontoid prolapse. The objective of this study was to evaluate the craniocervical angular craniometry of patients with BI compared with patients with Chiari malformation (CM) and normal subjects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183118
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http://dx.doi.org/10.1016/j.wneu.2018.05.233DOI Listing
September 2018
24 Reads

Evaluation of Soft Tissue Hypertrophy at the Retro-Odontoid Space in Patients with Chiari Malformation Type I on Magnetic Resonance Imaging.

World Neurosurg 2018 Aug 2;116:e1129-e1136. Epub 2018 Jun 2.

Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.

Introduction: Chiari malformation type I (CM-I) is a well-known hindbrain disorder in which the cerebellar tonsils protrude through the foramen magnum. The soft tissues, including the transverse ligament and the tectorial membrane at the retro-odontoid space, can compress the cervicomedullary junction if they become hypertrophic.

Methods: Twenty-two symptomatic patients with CM-I (aged 5-19 years) were treated between 2007 and 2017 at our institute. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.05.186DOI Listing
August 2018
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Revealing sub-voxel motions of brain tissue using phase-based amplified MRI (aMRI).

Magn Reson Med 2018 Dec 30;80(6):2549-2559. Epub 2018 May 30.

Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Purpose: Amplified magnetic resonance imaging (aMRI) was recently introduced as a new brain motion detection and visualization method. The original aMRI approach used a video-processing algorithm, Eulerian video magnification (EVM), to amplify cardio-ballistic motion in retrospectively cardiac-gated MRI data. Here, we strive to improve aMRI by incorporating a phase-based motion amplification algorithm. Read More

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http://doi.wiley.com/10.1002/mrm.27236
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http://dx.doi.org/10.1002/mrm.27236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269230PMC
December 2018
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Relationship of Morphologic Changes in the Brain and Spinal Cord and Disease Symptoms with Cerebrospinal Fluid Hydrodynamic Changes in Patients with Chiari Malformation Type I.

World Neurosurg 2018 Aug 23;116:e830-e839. Epub 2018 May 23.

Department of Biomedical Engineering, Islamic Azad University-Tehran North Branch, Tehran, Iran.

Background: Morphometric analysis or examination of symptoms in patients with Chiari malformation type I (CM-I) with various associations does not suffice for evaluation of surgical outcome of these patients. We assessed the relationship of morphologic changes in brain and spinal cord and disease symptoms with changes in cerebrospinal fluid (CSF) hydrodynamic parameters in patients with CM-I.

Methods: The study included 41 patients in 3 groups of CM-I, CM-I/occipitoatlantoaxial joint instability, and CM-I/tethered cord syndrome and 18 normal subjects. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.05.108DOI Listing
August 2018
2 Reads

Understanding and Treating Chiari-like Malformation and Syringomyelia in Dogs.

Top Companion Anim Med 2018 Mar 15;33(1):1-11. Epub 2018 Mar 15.

Department of Veterinary Clinical Sciences, The Ohio State University Veterinary Medical Center, Columbus, OH.

Chiari-like malformation (CM) and syringomyelia (SM) are common and debilitating conditions in toy and small breed dogs. CM, considered ubiquitous in the cavalier King Charles spaniel (CKCS) population, results in abnormal cerebrospinal fluid dynamics which can lead to the development of SM. The clinical signs associated with CM/SM are frequently confused with other otologic and dermatologic conditions, which may delay appropriate treatment. Read More

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http://dx.doi.org/10.1053/j.tcam.2018.03.002DOI Listing
March 2018
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Epidemiology of Symptomatic Chiari Malformation in Tatarstan: Regional and Ethnic Differences in Prevalence.

Neurosurgery 2019 May;84(5):1090-1097

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.

Background: Epidemiology can assess the effect of Chiari I malformation (CM1) on the neurological health of a population and evaluate factors influencing CM1 development.

Objective: To analyze the regional and ethnic differences in the prevalence of CM1.

Methods: The population of the Republic of Tatarstan (RT) in the Russian Federation was evaluated for patients with CM1 symptoms over an 11-yr period. Read More

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http://dx.doi.org/10.1093/neuros/nyy175DOI Listing
May 2019
6 Reads
3.620 Impact Factor

Orofacial clinical features in Arnold Chiari type I malformation: A case series.

J Clin Exp Dent 2018 Apr 1;10(4):e378-e382. Epub 2018 Apr 1.

Hospital da Restauração, Universidade de Pernambuco, Recife, PE, Brazil.

Background: Arnold Chiari malformation (ACM) is characterized by an anatomical defect at the base of the skull where the cerebellum and the spinal cord herniate through the foramen magnum into the cervical spinal canal. Among the subtypes of the condition, ACM type I (ACM-I) is particularly outstanding because of the severity of symptoms. This study aimed to analyze the orofacial clinical manifestations of patients with ACM-I, and discuss their demographic distribution and clinical features in light of the literature. Read More

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http://dx.doi.org/10.4317/jced.54419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937955PMC
April 2018
4 Reads

Relationship between Cough-Associated Changes in CSF Flow and Disease Severity in Chiari I Malformation: An Exploratory Study Using Real-Time MRI.

AJNR Am J Neuroradiol 2018 Jul 10;39(7):1267-1272. Epub 2018 May 10.

From the Departments of Radiology (A.F.B., D.K., R.A.B.).

Background And Purpose: Currently no quantitative objective test exists to determine disease severity in a patient with Chiari I malformation. Our aim was to correlate disease severity in symptomatic patients with Chiari I malformation with cough-associated changes in CSF flow as measured with real-time MR imaging.

Materials And Methods: Thirteen symptomatic patients with Chiari I malformation (tonsillar herniation of ≥5 mm) were prospectively studied. Read More

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http://dx.doi.org/10.3174/ajnr.A5670DOI Listing
July 2018
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Chiari I malformation with acute neurological deficit after craniocervical trauma: Case report, imaging, and anatomic considerations.

Surg Neurol Int 2018 23;9:88. Epub 2018 Apr 23.

Section of Neurological Surgery, Legacy Emanuel Hospital, Portland, Oregon, USA.

Background: In patients with Chiari I malformation (CMI), the occurrence of acute neurologic deficit after craniocervical trauma is rare. However, the pathologic potential of exacerbating anatomic overcrowding of the posterior fossa has immense clinical consequences and prompt recognition is essential.

Case Description: This case study describes a 41-year-old male who sustained a single blow to the face, fell, and struck the occiput. Read More

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http://surgicalneurologyint.com/surgicalint-articles/chiari-
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http://dx.doi.org/10.4103/sni.sni_304_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926209PMC
April 2018
6 Reads

Spontaneous Resolution of Chiari 1-Associated Syringomyelia: A Report of Two Cases.

Pediatr Neurosurg 2018 7;53(4):238-242. Epub 2018 May 7.

Background: Traditional teaching is that Chiari 1 malformations with syrinx should be operated as soon as possible. We present 2 cases of a radiologically proven Chiari 1 malformation with syrinx which were treated nonoperatively and improved radiologically.

Methods: Two children with an MRI-proven Chiari 1 malformations were followed up nonoperatively for 7 years (2010-2017). Read More

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http://dx.doi.org/10.1159/000488461DOI Listing
September 2018
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Case Report of Worth Syndrome and Chiari I Malformation: Unusual Association and Surgical Treatment.

World Neurosurg 2018 Jul 27;115:225-228. Epub 2018 Apr 27.

Department of Neurosurgery, José María Ramos Mejía General Hospital, Buenos Aires, Argentina.

Background: Worth syndrome or autosomal dominant endosteal hyperostosis (ADEH) is an extremely rare genetic disease involving increased bone density. To the author's knowledge, this is the second case report of a family with neurologic involvement associated with this condition along with its surgical treatment. The most effective treatment for clinically significant neurologic symptoms in this scenario is currently unknown, and there is sparse experience on surgical treatment for this condition reported in the literature. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.04.144DOI Listing
July 2018
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Long-Term Outcomes of a New Minimally Invasive Approach in Chiari Type 1 and 1.5 Malformations: Technical Note and Preliminary Results.

World Neurosurg 2018 07 24;115:407-413. Epub 2018 Apr 24.

Department of Radiology, Istanbul Training and Research Hospital, Istanbul, Turkey.

Background: The treatment options for patients with Chiari malformation type 1 (CM1) and Chiari malformation type 1.5 (CM1.5) have not yet been standardized. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183082
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http://dx.doi.org/10.1016/j.wneu.2018.04.100DOI Listing
July 2018
6 Reads