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Pediatr Neurosurg 2021 5;56(5):416-423. Epub 2021 Aug 5.

Neurosurgery Department, Shanghai Children's Medical Center Affiliated to the Medical School of Shanghai Jiaotong University, Shanghai, China.

Objective: This study aims to assess the impact of early diagnosis and surgery on children with congenital dermal sinus, investigate the relationship between MRI findings and extent of surgical exploration, and summarize our clinical experience with the surgical management in cases with central nervous system (CNS) infection.

Methods: The skin features, preoperative MRI images, intraoperative findings, postoperative pathological characteristics, and prognoses of 56 children with congenital dermal sinus were analyzed retrospectively.

Results: All the children had a pinpoint ostium in the skin, and 52 out of the 56 children (92. Read More

Childs Nerv Syst 2019 11 9;35(11):2163-2169. Epub 2019 Sep 9.

Department of Neurosurgery, Great Ormond Street Hospital for Children, London, UK.

Purpose: Lumbosacral lipoma (LSL) is a severe occult spinal dysraphism, frequently associated with neurological, urological and orthopaedic complications. Whole spine imaging is typically performed to identify concomitant, but spatially separate, congenital anomalies. Our hypothesis: the incidence of additional, clinically significant abnormalities of the neuraxis is low; thus, imaging should be optimised at the lumbosacral region. Read More

Neuroradiol J 2017 Dec 14;30(6):578-582. Epub 2017 Jul 14.

1 Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Aligarh Muslim University, India.

Encephalocraniocutaneous lipomatosis (ECCL) or Haberland syndrome is an uncommon sporadic neurocutaneous syndrome of unknown origin. The rarity and common ignorance of the condition often makes diagnosis difficult. The hallmark of this syndrome is the triad of skin, ocular and central nervous system (CNS) involvement and includes a long list of combination of conditions. Read More

Surg Neurol Int 2016 21;7(Suppl 38):S905-S907. Epub 2016 Nov 21.

Department of Neurosurgery, University of Medical Sciences, Rasool Akram Hospital, Tehran, Iran.

Background: Dermoid tumors are slow growing, benign CNS lesions.

Case Description: This case study concerns a 29-year-old female with a 6-year history of lower extremity paresthesias attributed to magnetic resonance (MR)/computed tomography (CT) documented intradural dermoid tumor that extended from L1 to S1. On MR, it was hypointense on T1, hyperintense on T2, and did not enhance with gadolinium. Read More

J Neurosurg Pediatr 2014 Dec 17;14(6):621-5. Epub 2014 Oct 17.

Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York; and 

Dermoid cysts are rare lesions of the CNS with a slow rate of growth. For this reason, they are rarely discovered during infancy. Although benign, these cysts may be associated with devastating complications due to mass effect or meningitis. Read More

Asian J Neurosurg 2012 Jan;7(1):42-4

Department of Neurosurgery, Grant Medical College and Sir J.J. Group of Hospitals, Byculla, Mumbai, Maharashtra, India.

Intracranial dermoid cysts are rare tumors. They constitute 0.3% of intracranial tumors. Read More

Surg Neurol 2008 Nov 8;70(5):531-5. Epub 2008 Feb 8.

Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.

Background: Dermoid cysts are very rare neoplasms in the CNS. The unusual neuroimaging signs and surgical treatment of the tumor are concerned in this case report.

Case Description: A 9-year-old boy complained of slight headache for 2 months, but complete physical examination showed no neurologic deficits on his admission. Read More

J Spinal Disord Tech 2004 Oct;17(5):405-11

Department of Neurosurgery, Catholic University of Taegu, Taegu City, South Korea.

Objective: To observe metabolic differences between spinal tumor and other diseases in human spinal mass lesions, in vivo 1H magnetic resonance spectroscopy (MRS) was attempted to obtain metabolic signals in patients with various spinal mass lesions.

Methods: 1H nuclear magnetic resonance (NMR) spectra were obtained from 14 patients before surgery using a receive-only surface coil on a 1.5 T clinical magnetic resonance imaging (MRI) unit. Read More

Clin Infect Dis 1993 Jun;16(6):766-71

Department of Pediatrics, Bowman Gray School of Medicine, Wake Forest University, Brenner Children's Hospital, Winston-Salem, North Carolina 27157.

Meningitis due to Staphylococcus aureus is uncommon, occurring primarily in patients with known preexisting abnormalities of the CNS (including patients who have undergone previous neurosurgery or trauma). We reviewed our experience with meningitis due to S. aureus in children seen at two medical centers. Read More