609 results match your criteria Imaging in Bronchiolitis Obliterans Organizing Pneumonia


Diagnostic Accuracy of Multidetector CT in Detection of Early Interstitial Lung Disease With Its Role in Characterization.

Cureus 2020 May 23;12(5):e8253. Epub 2020 May 23.

Radiodiagnosis, Era's Lucknow Medical College and Hospital, Lucknow, IND.

Background Multidetector CT (MDCT) has emerged as a useful option for early diagnosis of interstitial lung disease (ILD) with adequate accuracy. Methods A total of 80 patients with restricted pulmonary functions and clinical suspicion of ILD were enrolled in the study. MDCT evaluation was done using Siemens Somatom Force 384 slice multidetector computer tomography machine. Read More

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http://dx.doi.org/10.7759/cureus.8253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308819PMC

Chemotherapy-induced pulmonary complications in cancer: Significance of clinicoradiological correlation.

Indian J Radiol Imaging 2020 Jan-Mar;30(1):20-26. Epub 2020 Mar 30.

Department of Radiodiagnosis, Dr B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.

Chemotherapy while revolutionizing cancer management by improving survival and quality of life; is also associated with several adverse effects. Lung is the most common organ affected in chemotherapy-related complications, due to either drug toxicity or more commonly due to infections caused by immunosuppression and less commonly due to immune-mediated injury. Radiology, when used in combination with clinical and lab data, can help reach the specific diagnosis or narrow down the differentials. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_178_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240883PMC

Radiographic patterns of symptomatic radiation pneumonitis in lung cancer patients: Imaging predictors for clinical severity and outcome.

Lung Cancer 2020 Jul 30;145:132-139. Epub 2020 Apr 30.

Department of Imaging, Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA; Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address:

Objective: Investigate the spectrum of radiographic patterns of radiation pneumonitis (RP) in lung cancer patients and identify imaging markers for high-grade RP and RP-related death.

Methods: Eighty-two patients with lung cancer treated with conventional chest radiotherapy who had symptomatic RP were identified from the radiation oncology database. The imaging features of RP were studied for association with high-grade RP (Grade ≥3) and RP-related death (Grade 5). Read More

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http://dx.doi.org/10.1016/j.lungcan.2020.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316126PMC

Clinical and imaging characteristics of hematologic disease complicated by air leak syndrome: A STROBE-compliment observational study.

Medicine (Baltimore) 2020 May;99(20):e19948

Department of Radiology, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.

There are limited systematic studies on hematologic disease complicated by air leak syndrome (ALS). Physicians in radiology departments and hematology departments have a limited awareness of ALS.The aim of this study was to explore the similarities and differences in clinical data between the clinical group and imaging group in patients with hematologic disease complicated by ALS. Read More

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http://dx.doi.org/10.1097/MD.0000000000019948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254183PMC

[Chest High-resolution Computed Tomography Imaging Features of Lung Involvement in Rheumatoid Arthritis].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2020 Apr;42(2):202-208

Department of Radiology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

To explore the chest high-resolution computed tomography (HRCT) features in patients with rheumatoid arthritis (RA) complicated with pulmonary involvement. Totally 161 patients with RA with lung involvement were collected from June 2014 to May 2018. The chest HRCT findings were retrospectively analyzed. Read More

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http://dx.doi.org/10.3881/j.issn.1000-503X.12357DOI Listing

Machine Learning Algorithms to Differentiate Among Pulmonary Complications After Hematopoietic Cell Transplant.

Chest 2020 Apr 25. Epub 2020 Apr 25.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Stanford, CA. Electronic address:

Background: Pulmonary complications, including infections, are highly prevalent in patients after hematopoietic cell transplantation with chronic graft-vs-host disease. These comorbid diseases can make the diagnosis of early lung graft-vs-host disease (bronchiolitis obliterans syndrome) challenging. A quantitative method to differentiate among these pulmonary diseases can address diagnostic challenges and facilitate earlier and more targeted therapy. Read More

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http://dx.doi.org/10.1016/j.chest.2020.02.076DOI Listing

COVID-19 pneumonia: A review of typical CT findings and differential diagnosis.

Diagn Interv Imaging 2020 May 3;101(5):263-268. Epub 2020 Apr 3.

Department of Radiology, Cochin Hospital, Assistance Publique-Hopitaux de Paris, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France; Université de Paris, Descartes-Paris 5, 75006 Paris, France. Electronic address:

The standard of reference for confirming COVID-19 relies on microbiological tests such as real-time polymerase chain reaction (RT-PCR) or sequencing. However, these tests might not be available in an emergency setting. Computed tomography (CT) can be used as an important complement for the diagnosis of COVID-19 pneumonia in the current epidemic context. Read More

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http://dx.doi.org/10.1016/j.diii.2020.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129663PMC

Chest CT imaging features for prediction of treatment response in cryptogenic and connective tissue disease-related organizing pneumonia.

Eur Radiol 2020 May 10;30(5):2722-2730. Epub 2020 Feb 10.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

Objectives: To investigate CT imaging features associated with poor clinical outcome after corticosteroid treatment in patients diagnosed with cryptogenic organizing pneumonia (COP) and connective tissue disease-related organizing pneumonia (CTD-OP) and to assess the difference in CT findings and treatment responses between COP and CTD-OP.

Methods: Chest CT images from 166 patients (COP, 131; CTD-OP, 35) with pathologically proven organizing pneumonia were reviewed by two thoracic radiologists. The type, distribution pattern, and extent of parenchymal abnormalities, along with other associated imaging features, were assessed for each patient. Read More

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http://dx.doi.org/10.1007/s00330-019-06651-5DOI Listing
May 2020
4.014 Impact Factor

[Diffuse Intraparenchymal Mesothelioma: An Atypical Presentation].

Acta Med Port 2020 Feb 3;33(2):143-146. Epub 2020 Feb 3.

Serviço de Pneumologia. Hospital Pulido Valente. Centro Hospitalar de Lisboa Norte. Lisboa. Portugal.

Pleural mesothelioma is a disease associated with exposure to asbestos. Although rare, it is the most common malignant pleural neoplasm. It is difficult to diagnose and it has a poor prognosis. Read More

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http://dx.doi.org/10.20344/amp.11406DOI Listing
February 2020

Amiodarone-induced cryptogenic organizing pneumonia (COP).

Diagn Interv Imaging 2020 Jan 23. Epub 2020 Jan 23.

Institute of Pathology and Genetics, 6280 Loverval, Belgium.

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http://dx.doi.org/10.1016/j.diii.2020.01.004DOI Listing
January 2020

Cryptogenic Organizing Pneumonia with a Rare Radiographic Presentation of a Diffuse Micronodular Pattern Mimicking Miliary Lung Infiltration: A Case Report and Review of the Literature.

Case Rep Pulmonol 2020 3;2020:2094625. Epub 2020 Jan 3.

The Queen's Medical Center, Division of Pulmonary & Critical Care Medicine, Honolulu, HI 96813, USA.

We reported a case of cryptogenic organizing pneumonia (COP) presenting with an unusual diffuse micronodular pattern (DMP) mimicking miliary lung infiltration. The patient is a 66-year-old man with a past medical history of diabetes mellitus type 2 and hyperlipidemia who presented with progressive dyspnea associated with significant weight loss and night sweats for 2 weeks. Upon admission, the patient's clinical condition rapidly progressed to respiratory failure requiring mechanical ventilation. Read More

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http://dx.doi.org/10.1155/2020/2094625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961601PMC
January 2020

[Reversed halo sign as an unusual manifestation of cryptogenic organized pneumonia. Report of one case].

Rev Med Chil 2019 May;147(5):663-667

Facultad de Medicina, Clínica Alemana de Santiago, Universidad del Desarrollo, Chile.

We report a 64 years old female admitted with fever, cough, dyspnea and lung opacities in the chest X ray. A chest tomography scan (CTS) showed multiple-bilateral ring-shaped opacities and the reversed halo sign (RHS). The patient did not improve with antimicrobial therapy (AT). Read More

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http://dx.doi.org/10.4067/S0034-98872019000500663DOI Listing

Viral Pneumonia Requiring Differentiation from Acute and Progressive Diffuse Interstitial Lung Diseases.

Intern Med 2019 15;58(24):3509-3519. Epub 2019 Dec 15.

Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.

Objective The clinical characteristics and chest imaging findings of viral pneumonia and several interstitial lung diseases (ILDs) overlap, and viral pneumonia may be underrecognized and misdiagnosed as certain ILDs. To clarify the frequency of viral pneumonia among patients with acute progressive clinical courses that required a differential diagnosis between ILDs and pneumonia, and to determine the most frequent ILDs misdiagnosed in cases of viral pneumonia. Patients and Methods We retrospectively analyzed patients hospitalized from 2010 to 2017 with an acute clinical course (≤30 days) who underwent bronchoalveolar lavage (BAL) for the differential diagnosis of infection and ILDs. Read More

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http://dx.doi.org/10.2169/internalmedicine.2696-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949447PMC

Anaplastic lymphoma kinase inhibitor related pneumonitis in patients with non-small cell lung cancer: Clinical and radiologic characteristics and risk factors.

Medicine (Baltimore) 2019 Nov;98(48):e18131

Department of Pulmonary and Critical Care Medicine, and Division of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-Gu, Seoul, South Korea.

Anaplastic lymphoma kinase (ALK) inhibitor-related pneumonitis (ALK-IIP) is relatively rare but sometimes fatal, so the timely diagnosis of ALK-IIP is important for enabling prompt management. However, the detailed radiologic characteristics and clinical course of ALK-IIP are still unclear. This study was performed to investigate the clinical and radiologic characteristics and risk factors of ALK-IIP in patients with non-small cell lung cancer (NSCLC). Read More

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http://dx.doi.org/10.1097/MD.0000000000018131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890272PMC
November 2019

Durvalumab-induced Organizing Pneumonia with a Diffuse Micronodular Pattern in a Patient with Lung Cancer.

Am J Respir Crit Care Med 2020 04;201(8):e52-e53

Department of Molecular and Internal Medicine, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1164/rccm.201907-1310IMDOI Listing

Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease: Current Concepts for the Diagnosis and Treatment.

Front Med (Lausanne) 2019 23;6:238. Epub 2019 Oct 23.

Department of Rheumatology, Blackrock Clinic, Dublin, Ireland.

Rheumatoid arthritis (RA) is a type of inflammatory arthritis that affects ~1% of the general population. Although arthritis is the cardinal symptom, many extra-articular manifestations can occur. Lung involvement and particularly interstitial lung disease (ILD) is among the most common. Read More

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http://dx.doi.org/10.3389/fmed.2019.00238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819370PMC
October 2019

Concomitant Interstitial Lung Disease with Psoriasis.

Can Respir J 2019 25;2019:5919304. Epub 2019 Aug 25.

Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Background: We encounter interstitial lung disease (ILD) patients with psoriasis. The aim of this case series was to examine clinical and radiographic characteristics of patients with concomitant psoriasis and ILD.

Methods: This is a retrospective review of our institutional experience of ILD concomitant with psoriasis, from the database in the Advanced Lung/Interstitial Lung Disease Program at the Mount Sinai Hospital. Read More

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https://www.hindawi.com/journals/crj/2019/5919304/
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http://dx.doi.org/10.1155/2019/5919304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732645PMC
May 2020
2 Reads
1.663 Impact Factor

Two Cases of Primary Human Parainfluenza Virus 1 Pneumonia in Which Bronchoalveolar Lavage Fluid Yielded Human Parainfluenza Virus 1.

Intern Med 2020 Jan 11;59(1):101-105. Epub 2019 Sep 11.

Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.

Two patients, a 76-year-old woman and 66-year-old woman, presented to our hospital with symptoms of lower respiratory tract infection. Both patients showed chest imaging findings of bilateral ground-glass opacities and consolidations. We initially suspected these patients of having influenza-associated pneumonia and cryptogenic organizing pneumonia, respectively, and performed bronchoalveolar lavage, but only human parainfluenza virus-1 infection was detected by multiplex polymerase chain reaction testing. Read More

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http://dx.doi.org/10.2169/internalmedicine.3435-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995725PMC
January 2020
3 Reads

Thalidomide-induced bronchiolitis obliterans organizing pneumonia in a patient with multiple myeloma.

Saudi J Kidney Dis Transpl 2019 Jul-Aug;30(4):974-977

Department of Nephrology, La Rabta Hospital, Tunis, Tunisia.

Thalidomide, which is an angiogenesis inhibitor and immunomodulator that reduces tumor necrosis factor-alpha, has regained value in the treatment of multiple myeloma. Serious pulmonary complications due to thalidomide use remain relatively uncommon. We describe a case of bronchiolitis obliterans organizing pneumonia (BOOP) due to thalidomide. Read More

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http://dx.doi.org/10.4103/1319-2442.265477DOI Listing
February 2020
1 Read

Glucocorticoid treatment of suspected organizing pneumonia after H7N9 infection: A case report.

Medicine (Baltimore) 2019 Aug;98(34):e16839

Department of Neurosurgery, Zhongshan City People's Hospital, Zhongshan, China.

Rationale: H7N9 infection causes acute respiratory distress syndrome with high mortality. The use of glucocorticoids in the acute phase lessened inflammatory responses. Some case reports suggested that secondary organizing pneumonia (SOP) could occur at the recovery stage of the influenza virus infection, and the treatment with glucocorticoid was effective. Read More

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http://dx.doi.org/10.1097/MD.0000000000016839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716695PMC
August 2019
6 Reads

Acute fibrinous organising pneumonia presenting as a cavitary lung lesion and treatment response to azithromycin.

BMJ Case Rep 2019 Aug 21;12(8). Epub 2019 Aug 21.

Division of Pulmonary, Critical Care and Sleep Medicine, Baylor Scott & White Medical Center, Texas A & M University, College of Medicine, Temple, Texas, USA.

Acute fibrinous organising pneumonia is distinct from the classic diffuse alveolar damage, organising pneumonia and eosinophilic pneumonia. A 52-year-old woman presented with fever, productive cough, night sweats and left-sided pleuritic chest pain for a week. Physical examination was significant only for decreased breath sounds in the left infraclavicular area laterally. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2019-23086
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http://dx.doi.org/10.1136/bcr-2019-230868DOI Listing
August 2019
4 Reads

[Differences in small airway lesions in patients with different types of idiopathic interstitial pneumonia].

Zhonghua Yi Xue Za Zhi 2019 Aug;99(30):2325-2331

Department of Pulmonary and Critical Care Medicine in Respiratory Center, China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Disease, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing 100029, China.

To investigate the differences in small airway lesions in patients with different types of idiopathic interstitial pneumonia (IIPs). A total of 46 patients with IIPs confirmed by video assisted thoracoscopic or open lung biopsy, hospitalized in the Respiratory and Critical Care Medicine of Beijing Chao-Yang Hospital, from Dec. 1998 through Nov. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.30.002DOI Listing
August 2019
3 Reads

Refractory Metastatic Insulinoma Treated with Everolimus, Complicated by Cryptogenic Organizing Pneumonia.

Am J Med Case Rep 2019 18;7(7):125-132. Epub 2019 Jun 18.

Department of Medicine and Department of Endocrinology, State University of New York: Downstate Medical Center.

Insulinoma is a rare neuroendocrine pancreatic islet cell tumor of which the majority are benign and solitary. Its estimated incidence is 2 to 4 cases per 1 million person-years. We report the case of an 82-year-old female who presented with metastatic insulinoma to the liver and retroperitoneal lymph nodes. Read More

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http://dx.doi.org/10.12691/ajmcr-7-7-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693857PMC
June 2019
3 Reads

Focal organizing pneumonia simulating lung malignancy: treated with prednisolone.

Respirol Case Rep 2019 Oct 5;7(7):e00469. Epub 2019 Aug 5.

Pathology Virinchi Hospital Hyderabad India.

Focal cryptogenic organizing pneumonia (FOP) is a localized form of cryptogenic organizing pneumonia (COP). It is an uncommon clinicopathological entity associated with non-specific symptoms and radiographic findings simulating lung malignancy. Incidence of idiopathic FOP is not known and only reported as case series. Read More

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http://dx.doi.org/10.1002/rcr2.469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682542PMC
October 2019
1 Read

Lung Segmentation on HRCT and Volumetric CT for Diffuse Interstitial Lung Disease Using Deep Convolutional Neural Networks.

J Digit Imaging 2019 12;32(6):1019-1026

Department of Convergence Medicine and Radiology, Research Institute of Radiology and Institute of Biomedical Engineering, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

A robust lung segmentation method using a deep convolutional neural network (CNN) was developed and evaluated on high-resolution computed tomography (HRCT) and volumetric CT of various types of diffuse interstitial lung disease (DILD). Chest CT images of 617 patients with various types of DILD, including cryptogenic organizing pneumonia (COP), usual interstitial pneumonia (UIP), and nonspecific interstitial pneumonia (NSIP), were scanned using HRCT (1-2-mm slices, 5-10-mm intervals) and volumetric CT (sub-millimeter thickness without intervals). Each scan was segmented using a conventional image processing method and then manually corrected by an expert thoracic radiologist to create gold standards. Read More

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http://dx.doi.org/10.1007/s10278-019-00254-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841863PMC
December 2019
3 Reads

Squawks in interstitial lung disease prevalence and causes in a cohort of one thousand patients.

Medicine (Baltimore) 2019 Jul;98(29):e16419

Radiology Service, São Paulo Federal University, São Paulo, Brazil.

Squawks are lung adventitious sounds with a mix of both musical and nonmusical components heard during the inspiratory phase. Small series have described squawks in interstitial lung diseases. Hypersensitivity pneumonitis and other diseases involving small airways can result in squawks, but new interstitial lung diseases (ILDs) involving peripheral airways are being described. Read More

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http://dx.doi.org/10.1097/MD.0000000000016419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709015PMC
July 2019
3 Reads

Bronchoscopic features, associations, and outcomes of organizing pneumonia following allogeneic hematopoietic stem cell transplantation.

Ann Hematol 2019 Sep 4;98(9):2187-2195. Epub 2019 Jul 4.

Division of Hematologic Malignancies and Cellular Therapeutics, University of Kansas School of Medicine, Kansas City, KS, USA.

Organizing pneumonia (OP) is a poorly understood complication of hematopoietic stem cell transplant (HSCT). We identified 15 patients diagnosed with OP following HSCT and described their clinical course. CT chest findings were remarkable for multifocal infiltrates that were predominantly consolidating or ground glass opacities. Read More

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http://dx.doi.org/10.1007/s00277-019-03746-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080065PMC
September 2019
8 Reads

Characteristics and outcomes of patients hospitalized with interstitial lung diseases in Spain, 2014 to 2015.

Medicine (Baltimore) 2019 May;98(21):e15779

Respiratory Department, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid (UCM), Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM).

To assess characteristics and outcomes of patients hospitalized with interstitial lung diseases (ILD) and to analyze patient's comorbidities, procedures, and in-hospital outcomes.We identified patients hospitalized with idiopathic pulmonary fibrosis and others ILD such as hypersensitivity pneumonitis, cryptogenic organizing pneumonia, lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, and sarcoidosis in Spain during 2014 and 2015.We identified 14,565 discharges among patients admitted for ILD in Spain during the study period: idiopathic pulmonary fibrosis (IPF) in 42. Read More

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http://dx.doi.org/10.1097/MD.0000000000015779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571208PMC
May 2019
18 Reads

Percutaneous computed tomography-guided localization of pulmonary nodules with hook wire prior to video-assisted thoracoscopic surgery.

J BUON 2019 Jan-Feb;24(1):267-272

Radiology Department, St. Savvas Anticancer Hospital of Athens, Athens, Greece.

Purpose: To evaluate the use of percutaneous computed tomography (CT)-guided localization of suspicious intrapulmonary nodules with hook wire prior to video-assisted thoracoscopic surgery (VATS).

Methods: From April 2010 to February 2011, 15 patients with suspicious subpleural pulmonary nodules underwent preoperative CT-guided hook wire localization of the lesions, prior to VATS.

Results: Histological analysis of the resected suspicious pulmonary nodules revealed malignancy in 12 cases, 2 cases with granulomas and 1 case with bronchiolitis obliterans organizing pneumonia (BOOP). Read More

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August 2019
9 Reads
0.706 Impact Factor

Organizing Pneumonia after Nivolumab Treatment in a Patient with Pathologically Proven Idiopathic Pulmonary Fibrosis.

J Nippon Med Sch 2019 ;86(1):43-47

Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School.

Acute exacerbation of pre-existing interstitial lung disease (ILD) associated with systemic anticancer therapy is recognized as a life-threatening adverse event of lung cancer treatment. Programmed cell death 1 (PD-1) checkpoint inhibitors, such as nivolumab, often induce pneumonitis in patients with cancer; however, the tolerance and safety of nivolumab for advanced lung cancer with ILD are unclear. We report a 72-year-old patient with lung cancer with pathologically proven idiopathic pulmonary fibrosis who was treated with nivolumab. Read More

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https://www.jstage.jst.go.jp/article/jnms/86/1/86_JNMS.2019_
Publisher Site
http://dx.doi.org/10.1272/jnms.JNMS.2019_86-8DOI Listing
April 2019
36 Reads

Belimumab in refractory organizing pneumonia associated with systemic lupus erythematosus: a case report.

Lupus 2019 Apr 12;28(4):565-568. Epub 2019 Mar 12.

5 Department of Pathology, Ciudad Real University General Hospital, Ciudad Real, Spain.

Organizing pneumonia is an inflammatory lung entity that presents with a huge variety of clinical, radiological and pathological patterns. Organizing pneumonia can be idiopathic or secondary to other diseases. Corticosteroid therapy is usually the first-line treatment showing clinical improvement in most cases. Read More

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http://dx.doi.org/10.1177/0961203319835320DOI Listing
April 2019
11 Reads

Acute fibrinous and organizing pneumonia: A case report.

Medicine (Baltimore) 2019 Feb;98(8):e14537

Department of Infectious Disease.

Rationale: Acute fibrinous and organizing pneumonia (AFOP) is an uncommon type of acute lung injury associated with infection, connective tissue disorders, drug exposure, and hematologic malignancies.

Patient Concerns: A 53-year-old female presented with intermittent fever, chills, and dry cough since 10 days. Chest computed tomography scan showed multiple bilateral patchy infiltrates. Read More

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http://dx.doi.org/10.1097/MD.0000000000014537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408101PMC
February 2019
29 Reads
5.723 Impact Factor

Pulmonary involvement in Crohn's disease.

J Bras Pneumol 2018 Nov-Dec;44(6):519-521

. Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.

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http://dx.doi.org/10.1590/S1806-37562018000000055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459741PMC
March 2019
7 Reads

Cryptogenic Organizing Pneumonia Presenting as a Solitary Mass: Clinical, Imaging, and Pathologic Features.

Med Sci Monit 2019 Jan 16;25:466-474. Epub 2019 Jan 16.

Department of Radiology, Shanghai Dongfang Hospital, School of Medicine, Tongji University, Shanghai, China (mainland).

BACKGROUND Cryptogenic organizing pneumonia (COP), with a variety of radiologic findings, is a clinical pathological entity characterized by the presence of granulation tissue composed of fibroblasts/myofibroblasts and loose connective tissue in the alveoli and/or the distal bronchioles. Nevertheless, the presence of a solitary mass in COP is relatively rare. This study investigated the clinical, imaging, and pathologic features of COP with solitary mass form. Read More

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https://www.medscimonit.com/abstract/index/idArt/911655
Publisher Site
http://dx.doi.org/10.12659/MSM.911655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343522PMC
January 2019
31 Reads

Predictive factors for relapse of cryptogenic organizing pneumonia.

BMC Pulm Med 2019 Jan 9;19(1):10. Epub 2019 Jan 9.

Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.

Background: Relapse of cryptogenic organizing pneumonia (COP) may lead to poor long-term prognosis and necessitates multiple rounds of steroid treatment with potential adverse effects. The objective of this study is to identify predictive factors of COP relapse by comparing demographic and clinical variables between relapse and non-relapse groups.

Methods: During 2008-2013, 33 COP patients were treated, of which 23 (69. Read More

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https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890
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http://dx.doi.org/10.1186/s12890-018-0764-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327473PMC
January 2019
58 Reads

Bronchiolitis obliterans organizing pneumonia in Crohn's disease.

Gastroenterol Hepatol 2019 Oct 19;42(8):496-497. Epub 2018 Dec 19.

Servicio de Aparato Digestivo, Hospital San Pedro, Logroño, La Rioja, España.

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http://dx.doi.org/10.1016/j.gastrohep.2018.11.004DOI Listing
October 2019
6 Reads

Atoll sign: High resolution CT.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:17

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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http://doi.wiley.com/10.1111/1754-9485.05_12785
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http://dx.doi.org/10.1111/1754-9485.05_12785DOI Listing
October 2018
4 Reads

Fatale immunmediierte organisierende Pneumonie unter Pembrolizumab – Therapie eines pulmonalen Adenokarzinoms.

Rofo 2018 Dec 4;190(12):1161-1163. Epub 2018 Sep 4.

Department of Respiratory and Critical Care Medicine and Ludwig-Boltzmann-Institute of COPD and Respiratory Epidemiology, Otto-Wagner-Spital, Vienna, Austria.

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http://dx.doi.org/10.1055/a-0640-3290DOI Listing
December 2018
2 Reads

Breast cancer and organising pneumonia: the importance of correlating the pathological findings with the clinical and radiological picture.

BMJ Case Rep 2018 Aug 29;2018. Epub 2018 Aug 29.

Department of Respiratory Medicine, Mid Cheshire Hospitals NHS Foundation Trust, Crewe, UK.

This case describes a female patient with a history of breast cancer who presented with a persistent cough and weight loss after a 17-year disease-free period. Radiologically there were new bilateral intrapulmonary nodules and areas of consolidation with a broad differential diagnosis. Brushings gained via bronchoscopy were suggestive of malignancy, but subsequent video-assisted thoracoscopic surgery wedge resection demonstrated organising pneumonia (OP) with no evidence of malignancy. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22577
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http://dx.doi.org/10.1136/bcr-2018-225771DOI Listing
August 2018
19 Reads

Radiological findings of complications after lung transplantation.

Insights Imaging 2018 Oct 15;9(5):709-719. Epub 2018 Aug 15.

Division of Radiology, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Geneva, Switzerland.

Complications following lung transplantation may impede allograft function and threaten patient survival. The five main complications after lung transplantation are primary graft dysfunction, post-surgical complications, alloimmune responses, infections, and malignancy. Primary graft dysfunction, a transient ischemic/reperfusion injury, appears as a pulmonary edema in almost every patient during the first three days post-surgery. Read More

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http://dx.doi.org/10.1007/s13244-018-0647-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206387PMC
October 2018
16 Reads

Bronchiolitis obliterans organising pneumonia as an initial manifestation in a patient with systemic lupus erythematosus: a rare presentation.

BMJ Case Rep 2018 May 26;2018. Epub 2018 May 26.

Wayne State University, Detroit, Michigan, USA.

Bronchiolitis obliterans organising pneumonia as an initial manifestation of systemic lupus erythematosus (SLE) is a rare and uncommon presentation. We describe a case of SLE presenting with shortness of breath, found to have pneumothorax, bilateral nodular infiltrates along with pleural effusions and pericardial effusion. Work-up suggested a diagnosis of active SLE with anaemia, thrombocytopenia, positive antinuclear antibodies (ANAs) and positive anti-double-stranded DNA. Read More

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http://dx.doi.org/10.1136/bcr-2017-224094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976072PMC
May 2018
10 Reads

Transient Asymptomatic Pulmonary Opacities During Osimertinib Treatment and its Clinical Implication.

J Thorac Oncol 2018 08;13(8):1106-1112

Division of Hematology-Oncology, Departments of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

Introduction: Osimertinib is an oral, potent, irreversible third-generation EGFR tyrosine kinase inhibitor approved for the treatment of T790M-positive NSCLC patients who failed first- or second-generation EGFR tyrosine kinase inhibitors. Interstitial lung disease (ILD) is a rare complication with osimertinib, occurring in 1% to 3% of patients. Recently, a relatively high incidence of transient asymptomatic pulmonary opacities (TAPOs), which are different from ILD, has been described. Read More

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http://dx.doi.org/10.1016/j.jtho.2018.04.038DOI Listing
August 2018
23 Reads

Rituximab in the Treatment of Interstitial Lung Disease Associated with Antisynthetase Syndrome: A Multicenter Retrospective Case Review.

J Rheumatol 2018 06 1;45(6):841-850. Epub 2018 Apr 1.

From the Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, Massachusetts; Departments of Medicine and Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Objective: To assess clinical outcomes including imaging findings on computed tomography (CT), pulmonary function testing (PFT), and glucocorticoid (GC) use in patients with the antisynthetase syndrome (AS) and interstitial lung disease (ILD) treated with rituximab (RTX).

Methods: We retrospectively identified all patients at 2 institutions with AS-ILD who were treated with RTX. Baseline demographics, PFT, and chest CT were assessed before and after RTX. Read More

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http://dx.doi.org/10.3899/jrheum.170541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984657PMC
June 2018
33 Reads

Koinzidenz der kryptogen-organisierten Pneumonie und der perihepatischen Splenose – eine benigne Differenzialdiagnose zum metastasierten lepidischen Bronchialkarzinom.

Rofo 2018 07 7;190(7):640-642. Epub 2018 Mar 7.

Klinik und Poliklinik für Radiologie, Klinikum der Universität München, LMU München, Germany.

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http://dx.doi.org/10.1055/a-0576-1456DOI Listing
July 2018
12 Reads

Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature.

Exp Ther Med 2018 Jan 30;15(1):39-46. Epub 2017 Oct 30.

Department of Pharmacy, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing 100050, P.R. China.

Cryptogenic organizing pneumonia (COP) is a rare pulmonary disorder of unknown etiology. COP with hemoptysis as the primary presenting symptom has rarely been reported. The present study reported a case of COP that resembled lung carcinoma with hemoptysis as the only clinical symptom. Read More

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http://www.spandidos-publications.com/10.3892/etm.2017.5393
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http://dx.doi.org/10.3892/etm.2017.5393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769272PMC
January 2018
12 Reads

High incidence and early onset of nivolumab-induced pneumonitis: four case reports and literature review.

BMC Pulm Med 2018 Jan 30;18(1):23. Epub 2018 Jan 30.

Department of Thoracic Surgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

Background: Nivolumab, an anti-programmed cell death-1 (PD-1) monoclonal antibody used as an immune checkpoint inhibitor, is commonly employed for its anti-tumor effects against various types of malignant tumors. However, its administration is complicated by immune-related adverse events (irAEs), including pneumonitis.

Case Presentation: We present a case series of four patients with malignant melanoma, non-small cell lung cancer, and hypopharyngeal carcinoma who demonstrated pneumonitis induced by nivolumab, and further review clinicopathological characteristics of these patients in comparison with those of previously reported patients with nivolumab-induced pneumonitis. Read More

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http://dx.doi.org/10.1186/s12890-018-0592-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789617PMC
January 2018
15 Reads

[Clinical features of acute diffuse pulmonary exudative disorders].

Zhonghua Yi Xue Za Zhi 2017 Nov;97(44):3445-3449

Department of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

To analyze the clinical features of acute diffuse pulmonary exudative disorders. The data were collected from patients who were hospitalized in respiratory intensive care unit (RICU) of Beijing Chaoyang Hospital affiliated to the Capital Medical University during January 2009 to December 2011, and had acute clinical course with imaging findings of diffuse pulmonary infiltrated shadows (similar to acute respiratory distress syndrome (ARDS)). The causes of disease and clinical features were analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2017.44.002DOI Listing
November 2017
18 Reads

Cicatricial organising pneumonia mimicking a fibrosing interstitial pneumonia.

Histopathology 2018 Apr 29;72(5):846-854. Epub 2018 Jan 29.

Department of Radiology, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada.

Aims: Organising pneumonia (OP) is composed of loose granulation tissue plugs in distal airspaces; these disappear with steroid treatment. Recently a variant labelled 'cicatricial' OP has been described in which the granulation tissue organised to much denser fibrous tissue but still retained the usual pattern of OP. Here we report 10 patients thought to have an interstitial lung disease, and who on biopsy had a variant of cicatricial OP characterised by linear bands or small nodular masses of dense fibrous tissue that does not resemble ordinary OP. Read More

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http://doi.wiley.com/10.1111/his.13443
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http://dx.doi.org/10.1111/his.13443DOI Listing
April 2018
12 Reads

Pathology-radiology correlation of common and uncommon computed tomographic patterns of organizing pneumonia.

Hum Pathol 2018 01 7;71:30-40. Epub 2017 Nov 7.

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, 75235.

Organizing pneumonia (OP) is a common pattern of lung injury that can be associated with a wide range of etiologies. Typical and not-so-typical imaging features of OP occur, as both common and rare lung pathologies can mimic the same imaging pattern as that of OP. This article will attempt to describe the difference between confusing terminologies that have been used in the past for OP and existence of primary versus secondary OP. Read More

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http://dx.doi.org/10.1016/j.humpath.2017.10.028DOI Listing
January 2018
13 Reads

High-resolution computed tomography findings in chronic eosinophilic vs. cryptogenic organising pneumonia.

Int J Tuberc Lung Dis 2017 11;21(11):1181-1186

Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: The similar clinical and computed tomography (CT) characteristics of cryptogenic organising pneumonia (COP) and chronic eosinophilic pneumonia (CEP) make precise diagnosis challenging.

Objectives: To help differentiate between COP and CEP using high-resolution CT (HRCT).

Design: Clinical data and HRCT images of COP and CEP patients referred to Masih Daneshvari Hospital, Tehran, Iran, from 2007 to 2015 were reviewed. Read More

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http://dx.doi.org/10.5588/ijtld.16.0723DOI Listing
November 2017
5 Reads