2,514 results match your criteria Imaging in Bacterial Meningitis


Cerebral Vasculitis Complicating Pneumococcal Meningitis.

Eur J Case Rep Intern Med 2018 25;5(5):000819. Epub 2018 May 25.

Medical Intensive Care Unit, Farhat Hached Hospital, Sousse, Tunisia.

Introduction: Cerebral vasculitis is an uncommon life-threatening complication of community-acquired bacterial meningitis.

Patient And Methods: We report the case of a 64-year-old woman with pneumococcal meningitis who developed parainfectious vasculitis causing ischaemic brain damage. Cerebral magnetic resonance imaging (MRI) confirmed the diagnosis. Read More

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http://dx.doi.org/10.12890/2018_000819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346924PMC

Suspected bacterial meningoencephalomyelitis as the trigger or presentation of neuromyelitis optica spectrum disorder flare.

Mult Scler Relat Disord 2019 Feb 1;30:38-41. Epub 2019 Feb 1.

Neurology Department, Chinese PLA General Hospital, 28# Fuxing Road, Beijing, People's Republic of China; Medical School of Nankai University, 29# Weijing Road, Tianjin, People's Republic of China. Electronic address:

Background: Suspected bacterial meningoencephalomyelitis as the presentation or trigger of neuromyelitis optica spectrum disorders (NMOSD) flare has not been reported in literature.

Case Presentation: A 29 year old female, who has a history of neuromyelitis optica spectrum disorder (NMOSD) for 6 years, presented with symptoms of meningitits, encephalitis, myelitis, headache and fever. Cerebrospinal fluid analysis revealed pleocytosis (1131 × 10/L [83% neutrophils]) and a glucose level of 39. Read More

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http://dx.doi.org/10.1016/j.msard.2019.01.050DOI Listing
February 2019
1 Read

[Cranial computed tomography, lumbar puncture and clinical deterioration in bacterial meningitis: a nationwide cohort study].

Ned Tijdschr Geneeskd 2019 Feb 7;163. Epub 2019 Feb 7.

Amsterdamse UMC, afd. Neurologie, locatie AMC.

Background: Investigate how often cerebral herniation occurs following lumbar puncture (LP) in patients with bacterial meningitis, and whether cranial computed tomography (CT) can be used to identify patients at a higher risk of cerebral herniation.

Study Design: Prospective, nationwide cohort study covering the period March 2006 - November 2014.

Method: We identified patients with community-acquired bacterial meningitis who showed signs of clinical deterioration, possibly caused by LP. Read More

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February 2019
1 Read

[CT in patients suspected of bacterial meningitis? First antibiotics!]

Authors:
Korné Jellema

Ned Tijdschr Geneeskd 2019 Feb 7;163. Epub 2019 Feb 7.

Haaglanden Medisch Centrum, afd. Neurologie, Den Haag.

A lumbar puncture (LP) is often essential for the diagnosis of bacterial meningitis. An LP can worsen brain displacement in case of a space-occupying lesion. Therefore, in selected patients a CT scan of the brain is made prior to performing the LP. Read More

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February 2019
1 Read

Acute Bilateral Oculomotor Nerve Palsy in an Adult Patient with Neisseria meningitidis.

Intern Med 2019 Feb 1. Epub 2019 Feb 1.

Department of Cardiology, Komaki City Hospital, Japan.

A 69-year-old woman was admitted to our hospital with a fever, dizziness, and headache caused by Neisseria meningitidis. After ceftriaxone was administered, she suddenly developed bilateral oculomotor nerve palsy. Intra-orbital magnetic resonance imaging using appropriate sequences revealed that her bilateral third intracranial nerves were enlarged and enhanced. Read More

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http://dx.doi.org/10.2169/internalmedicine.2098-18DOI Listing
February 2019
1 Read

Recurrent Chemical Meningitis Due to Parasellar Epidermoid Cyst.

Cureus 2018 Oct 25;10(10):e3496. Epub 2018 Oct 25.

Neurology, Harbor University of California Los Angeles Medical Center, Los Angeles, USA.

Intracranial epidermoid cysts are exceedingly rare lesions that result from a disorder of gastrulation. They are seen only in the pediatric patient population. We describe a 44-year-old Hispanic woman who presented with acute confusion. Read More

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https://www.cureus.com/articles/15574-recurrent-chemical-men
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http://dx.doi.org/10.7759/cureus.3496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318134PMC
October 2018
4 Reads

Emerging Infection with in Neonate. A Case Report.

J Crit Care Med (Targu Mures) 2018 Jul 1;4(3):96-100. Epub 2018 Jul 1.

"Dunarea de Jos" University, Medicine and Pharmacy Research Centre, Galati Romania.

Background: are Gram-negative rod bacteria which are commonly found in the environment. The bacteria have also been associated with nosocomial infections, having been isolated on contaminated medical equipment, especially in neonatal wards.

Case Report: Here, we present the case of a premature female infant born at 33 weeks' gestational age, with neonatal meningitis. Read More

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http://content.sciendo.com/view/journals/jccm/4/3/article-p9
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http://dx.doi.org/10.2478/jccm-2018-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294984PMC
July 2018
7 Reads

Klebsiella pneumoniae and Klebsiella oxytoca meningitis in infants. Epidemiological and clinical features.

Arch Pediatr 2019 Jan 14;26(1):12-15. Epub 2018 Dec 14.

Service de pédiatrie, hôpitaux universitaires Paris Seine-Saint-Denis (HUPSSD) site Jean Verdier, université Paris XIII, AP-HP, avenue du 14 Juillet, 93140 Bondy, France; Groupe de pathologie infectieuse pédiatrique, 57, avenue de la Californie, 06200 Nice, France. Electronic address:

Background: The incidence of meningitis caused by Klebsiella pneumoniae (Kp) and Klebsiella oxytoca (Ko) in high-income countries is unknown, and no series have been published to date.

Methods: We conducted a nationwide multicenter observational study in France between 2006 and 2016. All children from the French national registry for paediatric bacterial meningitis under the age of 1 year and hospitalized for Kp or Ko meningitis were included. Read More

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http://dx.doi.org/10.1016/j.arcped.2018.09.013DOI Listing
January 2019
1 Read

Medical Referral Patterns and Etiologies for Children With Mild-to-Severe Hearing Loss.

Ear Hear 2018 Dec 6. Epub 2018 Dec 6.

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

Objectives: To (1) identify the etiologies and risk factors of the patient cohort and determine the degree to which they reflected the incidence for children with hearing loss and (2) quantify practice management patterns in three catchment areas of the United States with available centers of excellence in pediatric hearing loss.

Design: Medical information for 307 children with bilateral, mild-to-severe hearing loss was examined retrospectively. Children were participants in the Outcomes of Children with Hearing Loss (OCHL) study, a 5-year longitudinal study that recruited subjects at three different sites. Read More

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http://dx.doi.org/10.1097/AUD.0000000000000682DOI Listing
December 2018
11 Reads

Secondary pituitary abscess following transsphenoidal surgery with recurrent meningitis: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13458

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Rationale: The transsphenoidal surgical (TS) approach to sellar masses is the preferred surgical route in most cases. Secondary pituitary abscess (PA) following TS is an extremely rare but serious postoperative complication with potentially high disability and mortality.

Patient Concerns: We describe an uncommon case of secondary PA in a 42-year-old woman, who underwent uncomplicated transsphenoidal procedures without cerebrospinal fluid leak, to treat primary Rathke cleft cyst. Read More

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http://dx.doi.org/10.1097/MD.0000000000013458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283055PMC
November 2018
2 Reads

A Perplexing Case of Pituitary Apoplexy Masquerading as Recurrent Meningitis.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618811370. Epub 2018 Nov 15.

University of New Mexico Health Sciences Center, Albuquerque, NM, USA.

In this article, we present an exceptional case of pituitary apoplexy in which a patient presented with meningeal symptoms of headache, stiff neck, and nausea rather than the classical findings of ophthalmoplegia and/or vision loss. The patient has had 2 similar presentations with cerebrospinal fluid showing neutrophilic pleocytosis, as well as a computed tomography scan showing a prominent pituitary gland. On current presentation, the patient's vital signs were stable and the physical examination was remarkable for nuchal rigidity. Read More

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http://journals.sagepub.com/doi/10.1177/2324709618811370
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http://dx.doi.org/10.1177/2324709618811370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243406PMC
November 2018
9 Reads

Cerebrospinal fluid rhinorrhea in a bilateral frontal decompressive craniectomy patient caused by strenuous activity: A case report.

Medicine (Baltimore) 2018 Nov;97(47):e13189

Department of Neurosurgery.

Rationale: Iatrogenic cerebrospinal fluid (CSF) rhinorrhea in a bilateral frontal decompressive craniectomy patient triggered by strenuous sport is rare. To the best of our knowledge, no similar case has yet been reported.

Patient Concerns: Herein, we report a case of CSF rhinorrhea in a 37-year-old man. Read More

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http://dx.doi.org/10.1097/MD.0000000000013189DOI Listing
November 2018
7 Reads

Stroke in Pediatric Bacterial Meningitis: Population-Based Epidemiology.

Pediatr Neurol 2018 Dec 21;89:11-18. Epub 2018 Sep 21.

Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada; Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada; Department of Radiology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Community Health Services, University of Calgary, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada; Hotchkiss Brain Institute, Calgary, Alberta, Canada; Calgary Pediatric Stroke Program, University of Calgary, Calgary, Alberta, Canada. Electronic address:

Background: Bacterial meningitis is a severe infection of the nervous system with a high complication rate including stroke. The purpose of this study is to assess the incidence, risk factors, patterns, and outcomes in pediatric meningitis complicated by stroke.

Methods: The study design was a population-based, 10-year retrospective (2002 to 2012) cohort study set in Southern Alberta, Canada. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183089
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http://dx.doi.org/10.1016/j.pediatrneurol.2018.09.005DOI Listing
December 2018
13 Reads

Endoscopic Endonasal Repair of a Persistent Craniopharyngeal Canal and Sphenoid Meningoencephalocele: Case Report and Review of Literature.

World Neurosurg 2019 Feb 1;122:196-202. Epub 2018 Nov 1.

Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

Background: A persistent craniopharyngeal canal (PCC) is a rare cause of cerebrospinal fluid rhinorrhea in children. The condition often coexists with other midline facial defects, such as cleft palate. Children with PCC may also have pituitary dysfunction or neoplasms, such as craniopharyngiomas within the canal. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183243
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http://dx.doi.org/10.1016/j.wneu.2018.10.138DOI Listing
February 2019
10 Reads

A Double Whammy: Lactobacillus acidophilus Bacteremia and Subsequent Lactobacillus rhamnosus Prosthetic Valve Infective Endocarditis in an Elderly Diabetic Patient.

R I Med J (2013) 2018 Nov 1;101(9):32-35. Epub 2018 Nov 1.

Assistant Professor of Medicine, The Warren Alpert Medical School of Brown University, Department of Infectious Diseases, Providence VA Medical Center.

The clinical significance of the relatively avirulent organ- ism, Lactobacillus, has been debated in the past. At times misdiagnosed as a contaminant, Lactobacillus has uncommonly been reported to cause intra-abdominal abscesses, peritonitis, meningitis, bacteremia, pneumonia and endocarditis, especially in the population of patients with underlying comorbid conditions including malignancy, diabetes, recent surgery or organ transplantation. We report a case of a 74-year-old male with Lactobacillus bacteremia leading to prosthetic valve infective endocarditis complicated by an aortic root abscess. Read More

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November 2018
2 Reads

Methicillin-sensible causing endocarditis, with cerebral and orthopaedic complications, in a 17-month-old child with no risk factor.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Paediatric Mobile Emergency and Intensive Care Units, Hopital Universitaire Robert-Debre, Paris, France.

We report a case of endocarditis, with large vegetation, in a 17-month-old male infant, complicated with meningitis, ischaemic strokes and osteoarthritis leading to haemorrhagic stroke by aneurysm rupture. He did not present any risk factor for endocarditis. The final course was favourable through, after valve replacement. Read More

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http://dx.doi.org/10.1136/bcr-2018-226388DOI Listing
October 2018
2 Reads

Cerebrospinal fluid hydrocele caused by scrotal migration of a ventriculoperitoneal shunt.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Radiology, Aga Khan University, Karachi, Sindh, Pakistan.

A 6-month-old boy presented with painless right hemiscrotal swelling. The scrotal ultrasound revealed a cerebrospinal fluid hydrocele caused by the migration of a ventriculoperitoneal shunt (VPS) catheter tip into the right hemiscrotum and associated undescended left testis. Earlier, he underwent a VPS placement for hydrocephalus secondary to neonatal bacterial meningitis and ventriculitis. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22469
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http://dx.doi.org/10.1136/bcr-2018-224698DOI Listing
October 2018
13 Reads

Multidrug-Resistant Acinetobacter baumannii Ventriculostomy-Related Infection, Treated by a Colistin, Tigecycline, and Intraventricular Fibrinolysis.

World Neurosurg 2019 Jan 10;121:111-116. Epub 2018 Oct 10.

Department of Anesthesia and Surgical Intensive Care, Henri Mondor University Hospital of Paris, Paris XII School of Medicine, Creteil, France.

Background: Acinetobacter baumannii meningitis and ventriculitis are difficult issues, because of the low diffusion of antibiotics in the cerebrospinal fluid and bacterial multidrug resistance. The presence of an infected intraventricular hematoma, constituting an equivalent of undrained abscess, may promote biofilm formation and failure of medical treatment.

Case Description: In this case of ventriculostomy-related infection after ventricular hemorrhage, Acinetobacter baumannii was sensitive only to colistin and tigecycline. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183227
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http://dx.doi.org/10.1016/j.wneu.2018.09.218DOI Listing
January 2019
1 Read

Uncommon manifestation of leptospirosis: a diagnostic challenge.

BMJ Case Rep 2018 Oct 7;2018. Epub 2018 Oct 7.

Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi.

Leptospirosis is a zoonotic disease commonly affecting the tropical countries. It may have protean clinical manifestations including hepatorenal dysfunction, myocarditis, pulmonary haemorrhage, meningitis, optic neuritis and rhabdomyolysis. Neurological manifestation of leptospirosis without the classical hepatorenal dysfunction is a rare entity. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22528
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http://dx.doi.org/10.1136/bcr-2018-225281DOI Listing
October 2018
2 Reads

Epstein-barr virus-associated encephalitis in a case-series of more than 40 patients.

Wiad Lek 2018;71(6):1224-1230

Sumy State University, Sumy, Ukraine.

Objective: Introduction: Epstein-Barr virus (EBV) infection can present with neurologic manifestations including encephalitis, aseptic meningitis, Guillain-Barre syndrome, and many others. Most reported cases have been in children. Little is known about EBV encephalitis in adults. Read More

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January 2018
14 Reads

Central Nervous System Tuberculosis : Etiology, Clinical Manifestations and Neuroradiological Features.

Clin Neuroradiol 2018 Sep 17. Epub 2018 Sep 17.

Department of Neurology, Sankt Katharinen Hospital, Teaching Hospital, Goethe University, Frankfurt, Germany.

Purpose: As a result of multilateral migration and globalization in times of humanitarian crises, western countries face a possible increase in the incidence of central nervous system tuberculosis (CNS TB). The diagnosis of CNS TB is challenging and often delayed due to the manifold and often non-specific presentation of the disease. The aim of this review is to analyze and summarize imaging features and correlated clinical findings of CNS TB. Read More

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http://dx.doi.org/10.1007/s00062-018-0726-9DOI Listing
September 2018
2 Reads

Herpes simplex virus type 1 reactivation following a severe purulent meningitis in ICU.

Presse Med 2018 Sep 13;47(9):827-829. Epub 2018 Sep 13.

Abderrahmen Mami Pneumology Hospital, Medical Intensive Care Unit, Ariana, Tunisia; University of Tunis El Manar, Faculty of Medicine of Tunis, 1007 Tunis, Tunisia.

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http://dx.doi.org/10.1016/j.lpm.2018.06.002DOI Listing
September 2018
3 Reads

CD48 and α7 Nicotinic Acetylcholine Receptor Synergistically Regulate FimH-Mediated Escherichia coli K1 Penetration and Neutrophil Transmigration Across Human Brain Microvascular Endothelial Cells.

J Infect Dis 2019 Jan;219(3):470-479

Department of Histology and Embryology, School of Basic Medical Sciences, Wuhan University, China.

FimH-mediated bacterial invasion and polymorphonuclear neutrophil (PMN) transmigration across human brain microvascular endothelial cells (HBMECs) are required for the pathogenesis of Escherichia coli meningitis. However, the underlying mechanism remains unclear. This study demonstrated that the TnphoA mutant (22A33) and FimH-knockout mutant (ΔFimH) of E coli strain E44, which resulted in inactivation of FimH, were less invasive and less effective in promoting PMN transmigration than their wild-type strain. Read More

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http://dx.doi.org/10.1093/infdis/jiy531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325351PMC
January 2019
4 Reads
6.000 Impact Factor

Otogenic cerebral venous thrombosis in children: A review of 16 consecutive cases.

Int J Pediatr Otorhinolaryngol 2018 Oct 30;113:177-181. Epub 2018 Jul 30.

Department of Otorhinolaryngology, Centro Hospitalar São João, Porto, Portugal; Unit of Otorhinolaryngology, Department of Surgery & Physiology, University of Porto Medical School, Porto, Portugal; Center for Health Technology and Services Research (CINTESIS), Porto, Portugal.

Objectives: Management of otogenic cerebral venous thrombosis (OCVT) is controversial. Despite the modern antibiotic era OCVT still represents a potential life-threatening condition. This study aims to report the clinical presentation and management in a series of children with OCTV. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01655876183037
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http://dx.doi.org/10.1016/j.ijporl.2018.07.050DOI Listing
October 2018
9 Reads

Cochlear implantation in children with meningitis related deafness: The influence of electrode impedance and implant charge on auditory performance - A case control study.

Int J Pediatr Otorhinolaryngol 2018 Oct 24;113:102-109. Epub 2018 Jul 24.

Department of Otorhinolaryngology, Hannover Medical University, Carl-Neuberg-Straße 1, 30625, Hannover, Germany; German Hearing Center, Hannover Medical University, Karl-Wiechert-Allee 3, 30625, Hannover, Germany.

Objectives: Bacterial meningitis can cause a labyrinthitis. Consequences often are intracochlear soft tissue neoformation (cochlear obliteration) or intracochlear osteoneogenesis (cochlear ossification) and deafness. Cochlear implantation becomes challenging and hearing rehabilitation is complicated. Read More

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http://dx.doi.org/10.1016/j.ijporl.2018.07.034DOI Listing
October 2018
11 Reads

A Case of Recurrent Bacterial Meningitis Due to Retained 54-Year-Old Ureterodural Anastomosis.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618795293. Epub 2018 Aug 21.

Kern Medical-University of California Los Angeles, Bakersfield, CA, USA.

Ventriculoperitoneal shunts are the current treatment of choice for congenital hydrocephalus. It is rare for physicians to see patients with alternative types of shunting devices. Lumboureteral shunts, once popular from the 1940s to 1960s, decompress via the genitourinary system. Read More

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http://dx.doi.org/10.1177/2324709618795293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104220PMC
August 2018
7 Reads

Patterns of ischemic injury on brain images in neonatal group B Streptococcal meningitis.

Korean J Pediatr 2018 Aug 15;61(8):245-252. Epub 2018 Aug 15.

Department of Pediatrics, Dankook University College of Medicine, Cheonan, Korea.

Purpose: This study investigated patterns of ischemic injury observed in brain images from patients with neonatal group B Streptococcal (GBS) meningitis.

Methods: Clinical findings and brain images from eight term or near-term newborn infants with GBS meningitis were reviewed.

Results: GBS meningitis was confirmed in all 8 infants via cerebrospinal fluid (CSF) analysis, and patients tested positive for GBS in both blood and CSF cultures. Read More

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http://dx.doi.org/10.3345/kjp.2018.61.8.245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107402PMC
August 2018
13 Reads

Gold nanoparticles: A plausible tool to combat neurological bacterial infections in humans.

Biomed Pharmacother 2018 Nov 31;107:7-18. Epub 2018 Jul 31.

King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address:

Management of bacterial infections of central nervous system is a major challenge for the scientists all over the world. Despite the development of various potential drugs, the issue of central nervous system infections persists in the society. The main constraint is the delivery of drugs across the blood brain barrier and only a few drugs after meeting the stringent criteria could cross the blood brain barrier. Read More

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http://dx.doi.org/10.1016/j.biopha.2018.07.130DOI Listing
November 2018
3 Reads
2.023 Impact Factor

Calvarial osteomyelitis and intracranial extension post-Mohs micrographic surgery.

BMJ Case Rep 2018 Jul 26;2018. Epub 2018 Jul 26.

Internal Medicine, Hartford Hospital, Hartford, Connecticut, USA.

Mohs micrographic surgery (MMS) is a specialised micrographic technique used for the treatment of locally invasive skin cancers. Despite being a relatively low risk surgery, the overall complication rates range between 1.6% and 3%. Read More

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http://dx.doi.org/10.1136/bcr-2018-224861DOI Listing
July 2018
4 Reads

Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) associated with bacteria meningitis caused by listeria monocytogenes: A case report.

Medicine (Baltimore) 2018 Jul;97(30):e11561

Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Rationale: Mild encephalitis/encephalopathy with a reversible splenial lesion is a clinico-radiological syndrome mainly triggered by viral infection. Bacteria, like listeria monocytogenes, are relatively rare pathogens.

Patient Concerns: A two and a half years old girl with a 3-day history of fever and vomiting, complicated by a sudden seizure. Read More

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http://dx.doi.org/10.1097/MD.0000000000011561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078722PMC
July 2018
2 Reads

Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice.

Am J Pathol 2018 Oct 21;188(10):2164-2176. Epub 2018 Jul 21.

Gene Transfer Technology Group, University College London, London, United Kingdom; MRC Antiviral Gene Therapy Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Preterm birth is a serious global health problem and the leading cause of infant death before 5 years of age. At least 40% of cases are associated with infection. The most common way for pathogens to access the uterine cavity is by ascending from the vagina. Read More

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http://dx.doi.org/10.1016/j.ajpath.2018.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168615PMC
October 2018
5 Reads
4.591 Impact Factor

Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report.

Medicine (Baltimore) 2018 Jul;97(29):e11186

Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome.

Rationale: Tuberculous meningitis is a highly morbid, often fatal disease.

Patient Concern: We describe a case of an Italian child. DIAGNOSES:: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and paradoxical reaction with brain pseudo-abscesses. Read More

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http://dx.doi.org/10.1097/MD.0000000000011186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086519PMC
July 2018
4 Reads

Neurosyphilis and ocular syphilis clinical and cerebrospinal fluid characteristics: a case series.

Arq Neuropsiquiatr 2018 Jun;76(6):373-380

Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Medicina Interna, Serviço de Neurologia, Curitiba PR, Brasil.

Background: During the first decade of this century, a significant increase in the incidence of syphilis was documented.

Objective: To study clinical and laboratory characteristics of central nervous system and ocular syphilis.

Methods: A retrospective case series of 13 patients with a clinical and laboratory diagnosis of neurosyphilis and/or ocular syphilis who had been admitted to the Neurology and Neuro-ophthalmology Service of the Hospital de Clínicas, Federal University of Paraná. Read More

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http://dx.doi.org/10.1590/0004-282X20180054DOI Listing
June 2018
6 Reads

Diagnosis of Meningitis Caused by Pathogenic Microorganisms Using Magnetic Resonance Imaging: A Systematic Review.

Basic Clin Neurosci 2018 Mar-Apr;9(2):73-86

Department of Neurology, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Introduction: Bacterial meningitis is an acute infectious inflammation of the protective membranes covering the brain. Its early diagnosis is vital because of its high morbidity and mortality. It is mostly diagnosed by a gold standard diagnostic tool i. Read More

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http://dx.doi.org/10.29252/nirp.bcn.9.2.73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026091PMC
July 2018
11 Reads

Biot's breathing associated with acute bacterial meningitis in a child.

BMJ Case Rep 2018 Jun 29;2018. Epub 2018 Jun 29.

Paediatric Intensive Care Unit, Kaplan Medical Center, Rehovot, Israel.

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http://dx.doi.org/10.1136/bcr-2018-225774DOI Listing
June 2018
7 Reads

The Risk of Immunosuppression: A Case of Meningitis.

Case Rep Infect Dis 2018 21;2018:4874575. Epub 2018 May 21.

Lahey Hospital and Medical Center, 41 Burlington Mall Road, Burlington, MA 01805, USA.

meningitis is a rare infection, particularly in adults. We report the case of a 75-year-old female with a history of rheumatoid arthritis on TNF-antagonist immunosuppressive therapy who initially presented to the hospital for management of back and leg pain and was ultimately diagnosed with bacterial meningitis secondary to species infection. She was treated with ceftriaxone with slow improvement in neurological function. Read More

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http://dx.doi.org/10.1155/2018/4874575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987290PMC

A Pilot Study Evaluating Cerebral Vasculitis in Kawasaki's Disease.

Neuropediatrics 2018 Dec 18;49(6):392-396. Epub 2018 Jun 18.

Department of Pediatrics, Gyeongsang National University of Hospital, Jinju, Republic of Korea.

Cerebral vasculitis is thought to be a possible underlying mechanism of severe neurological complications of Kawasaki's disease (KD), such as cerebral infarct or aneurysm rupture. To evaluate the intracranial inflammatory response in patients with acute-stage KD, we measured the levels of cytokines (interleukin [IL]-6 and tumor necrosis factor [TNF]-α) and pentraxin-3 (PTX3) in the cerebrospinal fluid of patients with KD ( = 7) and compared the levels to those of the age- and sex-matched febrile control patients (bacterial meningitis [ = 5], enteroviral meningitis [ = 10], nonspecific viral illness without central nervous system involvement [ = 10]). PTX3 and TNF-α were rarely detected and only in trace concentration in KD, and the levels of IL-6 were not different from those of nonspecific viral illnesses. Read More

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http://dx.doi.org/10.1055/s-0038-1660855DOI Listing
December 2018
2 Reads

[Cerebral tuberculosis without meningitis in a immunocompetent child].

Rev Chilena Infectol 2018 04;35(2):207-212

Clínica Las Américas, Medellín, Colombia.

Cerebral tuberculosis TB (tuberculomas) without meningitis is an uncommon disease with a high morbidity and mortality. We report on a case that illustrates the complexity of this clinical presentation. An 11 month old, previously healthy male infant was brought to the clinic due to fever present during the last 1. Read More

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http://dx.doi.org/10.4067/s0716-10182018000200207DOI Listing
April 2018
10 Reads

Paradoxical Reaction in a Patient with Co-Occurring Tuberculous Meningitis and Pott's Disease.

Am J Case Rep 2018 Jun 16;19:699-704. Epub 2018 Jun 16.

Department of Internal Medicine, Section of Infectious Disease, Yale University School of Medicine, New Haven, CT, USA.

BACKGROUND Paradoxical reactions to tuberculosis (TB) are clinical or radiological worsening of prior tuberculous lesions or the development of new lesions upon treatment with appropriate anti-tuberculosis therapy (ATT). This phenomenon has been described in both HIV-seropositive and HIV-seronegative patients. Although historically estimated to occur in 6-30% of HIV-seronegative patients with TB, the phenomenon is often under-recognized in the current era, particularly in countries of low TB prevalence. Read More

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http://dx.doi.org/10.12659/AJCR.909194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034555PMC

Purulent meningitis caused by Rhodococcus equi: A case report.

Medicine (Baltimore) 2018 Jun;97(24):e11156

Department of Neurology.

Rationale: Purulent meningitis refers infection of the subarachnoid space by various purulent bacteria and the corresponding inflammation of the leptomeninges. However, purulent meningitis due to Rhodococcus equi is extremely rare.

Patient Concerns: A 40-year-old man presented with fever and intermittent headache for 6 days. Read More

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http://dx.doi.org/10.1097/MD.0000000000011156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023960PMC
June 2018
1 Read

Central nervous system blast crisis of chronic myeloid leukaemia misdiagnosed as tubercular meningitis.

BMJ Case Rep 2018 Jun 12;2018. Epub 2018 Jun 12.

Department of Neurology, Sawai Mansingh Medical College and Hospital, Jaipur, Rajasthan, India.

Chronic Myeloid Leukaemia (CML) presenting with isolated Central Nervous System (CNS) blast crisis is an uncommon entity. A 22-year-old man, diagnosed with chronic phase CML in 2011 and was in haematological and cytogenetic remission until July 2016, had acute onset headache and vomiting with meningeal signs and was admitted elsewhere, investigated by brain imaging and cerebrospinal fluid (CSF) analysis and suspected to have tubercular meningitis, for which steroids and antitubercular medications were started. The patient's sensorium further deteriorated, and Ventriculoperitoneal shunt surgery was done for hydrocephalus by a neurosurgeon. Read More

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http://dx.doi.org/10.1136/bcr-2017-223923DOI Listing
June 2018
3 Reads

Mortality from Listeria monocytogenes meningoencephalitis following escalation to alemtuzumab therapy for relapsing-remitting Multiple Sclerosis.

Mult Scler Relat Disord 2018 Aug 18;24:38-41. Epub 2018 May 18.

Bristol Brain Centre, Department of Neurosciences, North Bristol NHS Trust, Southmead Road, Westbury-On-Trym, BS10 5NB Bristol, United Kingdom. Electronic address:

We report the case of a patient who died from the rare complication of Listeriosis in the immediate phase following alemtuzumab administration one month after discontinuing dimethyl fumarate (DMF). There is considerable overlap with typical post-infusion symptoms therefore high surveillance and low threshold for empirical or possible prophylactic antibiotic therapy is advocated. Read More

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http://dx.doi.org/10.1016/j.msard.2018.05.014DOI Listing

Meningovascular syphilis causing recurrent stroke and diagnostic difficulties: a scourge from the past.

BMJ Case Rep 2018 Jun 8;2018. Epub 2018 Jun 8.

Department of Stroke, Nottingham University Hospitals NHS Trust, Nottingham, UK.

We describe a case of a 49-year-old man who presented with recurrent strokes in the left middle cerebral artery territory, manifesting with dysphasia, higher cognitive deficits, motor deficits and subsequent infarcts in the right middle cerebral and anterior cerebral artery territories, manifesting with seizures, behavioural and social issues. A key issue of the case was the diagnostic difficulty faced by the physicians. 'Meningovascular syphilis' was subsequently confirmed and appropriate treatment was given but there was subsequent relapse with worsening of the symptoms. Read More

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http://dx.doi.org/10.1136/bcr-2018-225255DOI Listing
June 2018
4 Reads

Pneumokokkensepsis und Osteoidosteom – eine seltene Koinzidenz.

Rofo 2018 Nov 6;190(11):1070-1072. Epub 2018 Jun 6.

Department of Radiology, HELIOS-Klinikum Berlin-Buch, Berlin, Germany.

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http://dx.doi.org/10.1055/a-0620-9034DOI Listing
November 2018
3 Reads

Bacterial meningitis in neonates and infants - the sonographic picture.

J Ultrason 2018 Mar 30;18(72):63-70. Epub 2018 Mar 30.

Laboratory of Diagnostic Ultrasound and Biopsy, Department of Pediatrics, Oncology, Hematology and Endocrinology, University Clinical Center in Gdańsk, Gdańsk, Poland.

Bacterial meningitis is a major diagnostic and therapeutic problem among children and neonates, with severe, rapidly progressing course and potentially life-threatening complications. Early antibacterial treatment is essential for the patient's favorable prognosis. Cerebral imaging plays an important role in the diagnostic process alongside physical examination and laboratory tests. Read More

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http://dx.doi.org/10.15557/JoU.2018.0010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911721PMC
March 2018
2 Reads

Role of Immuno-Polymerase Chain Reaction (I-PCR) in Resolving Diagnostic Dilemma Between Tuberculoma and Neurocysticercosis: A Case Report.

Am J Case Rep 2018 May 24;19:599-603. Epub 2018 May 24.

Centre for Biotechnology, Maharshi Dayanand University (MDU), Rohtak, Haryana, India.

BACKGROUND Tuberculoma and neurocysticercosis (NCC) often show similar clinical and neuroimaging features. Differential diagnosis of these 2 diseases is imperative, as tuberculoma is an active infection that requires immediate anti-tubercular therapy (ATT). CASE REPORT We present the case of a 17-year-old Indian girl with fever, severe headache, and right 6th cranial nerve palsy. Read More

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http://dx.doi.org/10.12659/AJCR.908624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994961PMC
May 2018
4 Reads

Enhanced brain penetration of pretomanid by intranasal administration of an oil-in-water nanoemulsion.

Nanomedicine (Lond) 2018 05 23;13(9):997-1008. Epub 2018 May 23.

Catalysis & Peptide Research Unit, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4000, South Africa.

Aim: To enhance the drug delivery to the brain with an oil-in-water nanoemulsion of pretomanid via intranasal (IN) administration.

Materials & Methods: The study involved 70 male Sprague-Dawley rats (160-180 g) that received either 20 mg/kg body weight (b.w. Read More

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http://dx.doi.org/10.2217/nnm-2017-0365DOI Listing
May 2018
4 Reads
5.413 Impact Factor

Primary bacterial ventriculitis in adults, an emergent diagnosis challenge: report of a meningoccal case and review of the literature.

BMC Infect Dis 2018 05 18;18(1):226. Epub 2018 May 18.

Infectious Disease, Rouen University Hospital, Rouen, France.

Background: Defined by an infection of the ventricular system of the brain, ventriculitis is usually known as a health-care associated infection. In contrast, primary pyogenic ventriculitis complicating community-acquired meningitis is uncommon, and mainly described in infants. Only seven cases that have occured in adults have been found in the international literature. Read More

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http://dx.doi.org/10.1186/s12879-018-3119-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960165PMC
May 2018
9 Reads

Retrobulbar steatitis and meningitis/empyema secondary to right otitis media, right otitis interna and an inflammatory polyp in a cat.

Open Vet J 2018 29;8(2):144-148. Epub 2018 Apr 29.

Dick White Referrals, Station Farm, London Road, Six Mile Bottom, Cambridgeshire CB8 0UH, UK.

The purpose was to describe a case of retrobulbar steatitis and meningitis in a cat caused by otitis media, otitis interna and an inflammatory polyp in the middle ear. Investigations included ophthalmic and neurological examinations, haematology and biochemistry, magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) analysis and aerobic, anaerobic bacterial and fungal culture of material from the middle ear. A 6-year-old female neutered domestic-short-haired cat presented with right-sided exophthalmos and resistance to retropulsion. Read More

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https://www.ajol.info/index.php/ovj/article/view/170605
Publisher Site
http://dx.doi.org/10.4314/ovj.v8i2.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943686PMC
April 2018
5 Reads

Recurrent Streptococcus pneumoniae meningitis and Mondini dysplasia: Association or causation?

J Infect Public Health 2019 Jan - Feb;12(1):101-103. Epub 2018 Apr 26.

Department of Radio-diagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. Electronic address:

Mondini dysplasia is a developmental disorder of the inner ear structures and it is a rare cause of recurrent bacterial meningitis in children. A 10-year-old boy presented with acute febrile encephalopathy and right ear pain. In the past, he had suffered from two distinct episodes of pyogenic meningitis. Read More

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http://dx.doi.org/10.1016/j.jiph.2018.04.002DOI Listing
April 2018
9 Reads