4,414 results match your criteria Imaging in Avascular Necrosis of the Femoral Head


[Effectiveness comparison between impacting bone graft and rotational osteotomy via surgical hip dislocation approach for avascular necrosis of femoral head at ARCO stage ].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Apr;33(4):445-450

Department of Traumatology & Orthopedics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing Jiangsu, 210029,

Objective: To compare effectiveness between sequestrum clearance and impacting bone graft and rotational osteotomy on the base of femoral neck via surgical hip dislocation approach for avascular necrosis of femoral head (ANFH) at Association Research Circulation Osseous (ARCO ) stage Ⅲ.

Methods: A clinical data of 24 patients (27 hips) with ANFH at ARCO stage Ⅲ, who met the inclusion criteria between June 2012 and November 2017, was retrospectively analysed. Of all patients, 12 patients (14 hips) were treated with sequestrum clearance and impacting bone graft via surgical hip dislocation approach (group A); and 12 patients (13 hips) were treated with rotational osteotomy on the base of femoral neck via surgical hip dislocation approach (group B). Read More

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http://dx.doi.org/10.7507/1002-1892.201811120DOI Listing
April 2019
2 Reads

[Comparison between pathology and computer for quantitative determination of femoral head necrosis].

Zhongguo Gu Shang 2019 Feb;32(2):146-150

Department of Orthopaedics, the Second Affiliated Hospital of Zhejiang Traditional Chinese Medicine University, Hangzhou 310005, Zhejiang, China;

Objective: To compare computer measurement semi automatic quantitative detection software system with ultra thin layer pathological section to confirm the avascular necrosis percentage of the femoral head, and provide reference for clinical treatment options.

Methods: From June 2012 to December 2013, the X-ray and MRI of 24 patients(24 hips on unilateral) were reviewed, who had avascular necrosis of the femoral head at late stage (stage III and IV) according to the ARCO international staging system, and performed by total hip arthroplasty. There were 15 males and 9 females, with an average age of (65. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2019.02.010DOI Listing
February 2019
3 Reads

Osteonecrosis of the Femoral Head.

Orthop Clin North Am 2019 Apr 12;50(2):139-149. Epub 2019 Feb 12.

Department of Orthopedic Surgery, University of Virginia, University of Virginia School of Medicine, 400 Ray C. Hunt Drive, #300, Charlottesville, VA 22903, USA. Electronic address:

Osteonecrosis of the femoral head most commonly arises from trauma or corticosteroid and alcohol use but is also associated with blood dyscrasias and metabolic and coagulation disorders. Initial evaluation includes a history and physical examination and plain radiographs. Early-stage osteonecrosis is best evaluated by MRI. Read More

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http://dx.doi.org/10.1016/j.ocl.2018.10.001DOI Listing
April 2019
1 Read

Differences in magnetic resonance findings between symptomatic and asymptomatic pre-collapse osteonecrosis of the femoral head.

Eur J Radiol 2019 Mar 4;112:1-6. Epub 2019 Jan 4.

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address:

Purpose: The purpose of this study was to assess the differences in magnetic resonance (MR) findings between the symptomatic and asymptomatic pre-collapse stage of osteonecrosis of the femoral head (ONFH).

Materials And Methods: This study reviewed 123 consecutive hips in 91 patients in the pre-collapse stage of ONFH based on plain radiographic findings. These 123 hips were divided into symptomatic and asymptomatic groups according to the pain domain score in the Harris hip score system. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.002DOI Listing
March 2019
1 Read

Closed Reduction for Developmental Dysplasia of the Hip: Early-term Results From a Prospective, Multicenter Cohort.

J Pediatr Orthop 2019 Mar;39(3):111-118

Arnold Palmer Medical Center, Orlando, FL.

Background: Closed reduction (CR) is a common treatment for infantile developmental dysplasia of the hip. The purpose of this observational, prospective, multicenter study was to determine the early outcomes following CR.

Methods: Prospectively collected data from an international multicenter study group was analyzed for patients treated from 2010 to 2014. Read More

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http://dx.doi.org/10.1097/BPO.0000000000000895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416015PMC
March 2019
2 Reads

Detection of avascular necrosis on routine diffusion-weighted whole body MRI in patients with multiple myeloma.

Br J Radiol 2019 May 12;92(1097):20180822. Epub 2019 Feb 12.

4 Department of Radiology, The Royal Marsden Hospital and Faculty of Radiotherapy and Imaging Institute of Cancer Research , London , UK.

Objective: Current therapies for multiple myeloma, which include corticosteroids, increase risk of avascular necrosis. The aim of this study was to assess incidental detection of femoral head avascular necrosis on routine whole body MRI including diffusion weighted MRI.

Methods: All whole body MRI studies, performed on patients with known multiple myeloma between 1 January 2010 to 1 May 2017 were assessed for features of avascular necrosis. Read More

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https://www.birpublications.org/doi/10.1259/bjr.20180822
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http://dx.doi.org/10.1259/bjr.20180822DOI Listing
May 2019
2 Reads
1.533 Impact Factor

[Lead intoxication revealing sickle cell disease].

Pan Afr Med J 2018 31;30:305. Epub 2018 Aug 31.

Service de Rhumatologie, CHU Mohammed VI, BP 2360 principal, Avenue Ibn Sina, Marrakech, Maroc.

We here report the case of a 18 year old patient with two brothers who died from sickle cell anemia. He had a 5-day history of diffuse bone pain. He had drunk a preparation containing lead to obtain an analgesic effect without improvement. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.305.16222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320453PMC
January 2019
2 Reads

Prediction of mechanical behavior of cartilaginous infant hips in pavlik harness: A subject-specific simulation study on normal and dysplastic hips.

J Orthop Res 2019 Mar 12;37(3):655-664. Epub 2019 Feb 12.

Department of Radiology and Diagnostic Imaging, University of Alberta, 2A2.41 WMC, 8440-112 Street, Edmonton, Alberta, T6G 2B7, Canada.

In dysplastic infant hips undergoing abduction harness treatment, cartilage contact pressure is believed to have a role in therapeutic cartilage remodeling and also in the complication of femoral head avascular necrosis. To improve our understanding of the role of contact pressure in the remodeling and the complication, we modeled cartilage contact pressure in cartilaginous infant hips undergoing Pavlik harness treatment. In subject-specific finite element modeling, we simulated contact pressure of normal and dysplastic hips in Pavlik harness at 90° flexion and gravity-induced abduction angles of 40°, 60° and 80°. Read More

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http://dx.doi.org/10.1002/jor.24213DOI Listing
March 2019
4 Reads

Segmentation of the proximal femur in radial MR scans using a random forest classifier and deformable model registration.

Int J Comput Assist Radiol Surg 2019 Mar 2;14(3):545-561. Epub 2019 Jan 2.

School of Health Sciences - Geneva, HES-SO University of Applied Sciences and Arts Western Switzerland, Avenue de Champel 47, 1206, Geneva, Switzerland.

Background: Radial 2D MRI scans of the hip are routinely used for the diagnosis of the cam type of femoroacetabular impingement (FAI) and of avascular necrosis (AVN) of the femoral head, both considered causes of hip joint osteoarthritis in young and active patients. A method for automated and accurate segmentation of the proximal femur from radial MRI scans could be very useful in both clinical routine and biomechanical studies. However, to our knowledge, no such method has been published before. Read More

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http://link.springer.com/10.1007/s11548-018-1899-z
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http://dx.doi.org/10.1007/s11548-018-1899-zDOI Listing
March 2019
19 Reads

Avascular necrosis of the femoral head: An exceptional complication of cushing's disease.

Ann Afr Med 2018 Oct-Dec;17(4):225-227

Department of Endocrinology and Diabetology, University Hospital of Fez, Fez, Morocco.

Avascular necrosis (AVN) of the femoral head is a well-recognized complication of steroid treatment. Exogenous glucocorticoids' administration and alcoholism are the most common nontraumatic etiologies. AVN secondary to endogenous hypercortisolism (HC) is rare; very few case reports are available on this complication. Read More

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http://dx.doi.org/10.4103/aam.aam_75_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330779PMC
December 2018
15 Reads

Incidence and severity of femoral head avascularity after femoral neck or intertrochanteric fractures on preoperative bone single photon emission computed tomography/computed tomography: preliminary study.

Nucl Med Commun 2019 Mar;40(3):199-205

Department of Nuclear Medicine, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Cyclotron Research Center, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital.

Objective: The aim of the present study was to evaluate the incidence and degree of femoral head avascularity depending on the types of femoral neck or intertrochanteric fractures using preoperative bone single photon emission computed tomography (SPECT)/computed tomography (CT).

Patients And Methods: A total of 131 patients with femoral neck or intertrochanteric fractures who underwent preoperative bone SPECT/CT were enrolled. Femoral head avascularity was evaluated using bone SPECT/CT images. Read More

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http://dx.doi.org/10.1097/MNM.0000000000000963DOI Listing
March 2019
4 Reads

Autologous stem cell implantation with core decompression for avascular necrosis of the femoral head.

J Clin Orthop Trauma 2018 Oct-Dec;9(4):349-352. Epub 2018 Jun 2.

Department of Orthopaedic Surgery, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, USA.

Objective: Avascular necrosis (AVN) of the femoral head is a painful, progressive disease that can lead to limited mobility and early hip replacement. Autologous stem cell implantation into the necrotic lesion of the femoral head has been described, on the basis that patients with AVN have a reduced number of stem cells in the marrow. In this study, we aim to describe our technique for decompression of the hip with autologous implantation of stem cells for AVN of the femoral head, as well as retrospectively analyze our results. Read More

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http://dx.doi.org/10.1016/j.jcot.2018.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224688PMC
June 2018
13 Reads

Autologous bone marrow-derived CD133 cells with core decompression as a novel treatment method for femoral head osteonecrosis: a pilot study.

Cytotherapy 2019 Jan 5;21(1):107-112. Epub 2018 Nov 5.

Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Academic Center for Education, Culture and Research, Tehran, Iran. Electronic address:

Background: Avascular necrosis (AVN) of femoral head is a progressive bone disease due to ischemia of femoral head; patients experience pain and they can not do normal activity. There is not an effective way to treat the cause of this disease. In recent studies, treatment of this disease using pluripotent stem cell-derived mesenchyme is safe and effective, but this method needs more investigation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14653249183064
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http://dx.doi.org/10.1016/j.jcyt.2018.10.005DOI Listing
January 2019
14 Reads

Analysis of the long-term efficacy of core decompression with synthetic calcium-sulfate bone grafting on non-traumatic osteonecrosis of the femoral head.

Med Sci (Paris) 2018 Oct 7;34 Focus issue F1:43-46. Epub 2018 Nov 7.

Department of general surgery, 6th affiliated hospital of Wenzhou medical university (Lishui People's Hospital), Lishui Zhejiang province, No.15 Dazhong Road, Liandu district, Lishui 323000 PR China.

Objective: to investigate the safety and long-term efficacy of core decompression with synthetic calcium-sulfate bone grafting on non-traumatic osteonecrosis of the femoral head.

Method: a total of 76 patients with non-traumatic osteonecrosis of the femoral head were admitted to our hospital from February 2012 to November 2014 and included in the study. All the patients were treated by core decompression with synthetic calcium-sulfate bone grafting. Read More

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http://dx.doi.org/10.1051/medsci/201834f108DOI Listing
October 2018
2 Reads

Pericollapse Stage of Osteonecrosis of the Femoral Head: A Last Chance for Joint Preservation.

Chin Med J (Engl) 2018 Nov;131(21):2589-2598

Department of Orthopaedic, Graduate School of Peking Union Medical College, China-Japan Friendship Hospital Institute of Clinical Medicine, Beijing 100029, China.

Objective: To propose a new definition of the pericollapse stage of osteonecrosis of the femoral head (ONFH) and review its significance in disease diagnosis and treatment selection.

Data Sources: A search for eligible studies was conducted in three electronic databases including PubMed, Cochrane Library, and Embase up to August 10, 2018, using the following keywords: "osteonecrosis", "prognosis", and "treatment".

Study Selection: Investigations appraising the clinical signs, symptoms, and imaging manifestations in different stages of ONFH were included. Read More

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http://dx.doi.org/10.4103/0366-6999.244111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213842PMC
November 2018
4 Reads

Risk of avascular necrosis of the femoral head in children with sickle cell disease on hydroxyurea: MRI evaluation.

Pediatr Blood Cancer 2019 Feb 21;66(2):e27503. Epub 2018 Oct 21.

Department of Pediatrics, Faculty of Medicine, Kuwait University, Safat, Kuwait.

Background: There are conflicting reports on the role of hydroxyurea (HU) in the pathogenesis of avascular necrosis of the femoral head (AVNFH) in patients with sickle cell disease (SCD).

Procedure: The present study is a prospective cohort study of Kuwaiti children with SCD who were treated with HU. They had magnetic resonance imaging of the hips before starting HU and at regular intervals during a follow-up period, ranging from 1 to 15 years. Read More

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http://doi.wiley.com/10.1002/pbc.27503
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http://dx.doi.org/10.1002/pbc.27503DOI Listing
February 2019
29 Reads

Microbubble-Mediated Ultrasound Outweighs Low-Intensity Pulsed Ultrasound on Osteogenesis and Neovascularization in a Rabbit Model of Steroid-Associated Osteonecrosis.

Biomed Res Int 2018 12;2018:4606791. Epub 2018 Sep 12.

Department of Orthopaedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Jie-fang Road 88, Hangzhou, 310009, China.

Microbubbles magnify the acoustic pressure of low-intensity pulsed ultrasound (LIPUS) and may enhance its bioeffect for diagnostic and therapeutic purposes. This study compared the effect of this novel microbubble-mediated ultrasound (MUS) with that of the traditional LIPUS on osteogenesis and neovascularization in a rabbit model of steroid-associated osteonecrosis. We hypothesized that MUS might outweigh LIPUS on promoting osteogenesis and neovascularization in steroid-associated osteonecrosis. Read More

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https://www.hindawi.com/journals/bmri/2018/4606791/
Publisher Site
http://dx.doi.org/10.1155/2018/4606791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157205PMC
January 2019
4 Reads

Electromagnetic simulation for diagnosing damage to femoral neck vasculature: A feasibility study.

J Orthop 2018 Dec 6;15(4):997-1003. Epub 2018 Sep 6.

Department of Electrical and Computer Engineering, Indiana University Purdue University Indianapolis (IUPUI), 723 West Michigan Street, Indianapolis, Inn, 46202, United States.

Background: Femoral neck fractures are common injuries managed by orthopedic surgeons across the world. From pediatrics to geriatrics, disruption of the blood supply to the femoral neck is a well-recognized source of morbidity and mortality, oftentimes resulting in avascular necrosis of the femoral head. This devastating complication occurs in 10-45% of femoral neck fractures. Read More

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http://dx.doi.org/10.1016/j.jor.2018.08.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140380PMC
December 2018
2 Reads

Height-Width Ratio of Proximal Femoral Epiphysis: Estimation of Lateral Pillar Involvement in Bilateral Perthes Disease.

J Pediatr Orthop 2018 Nov/Dec;38(10):e577-e583

Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University.

Background: The standard evaluation of epiphyseal involvement in Perthes disease is lateral pillar classification. However, it needs to be compared with contralateral normal hip leading to limited use in bilateral disease. We, therefore, develop a ratio between epiphyseal height and metaphyseal width of affected hips to estimate lateral pillar involvement. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001252DOI Listing
December 2018
2 Reads

Lantern-shaped screw loaded with autologous bone for treating osteonecrosis of the femoral head.

BMC Musculoskelet Disord 2018 Sep 5;19(1):318. Epub 2018 Sep 5.

Orthopaedic Center of People's Liberation Army, The Affiliated Southeast Hospital of Xiamen University, Zhangzhou, 363000, China.

Background: Treatment for osteonecrosis of the femoral head (ONFH) in young individuals remains controversial. We developed a lantern-shaped screw, which was designed to provide mechanical support for the femoral head to prevent its collapse, for the treatment of ONFH. The purpose of this study was to investigate the efficacy and safety of the lantern-shaped screw loaded with autologous bone for the treatment of pre-collapse stages of ONFH. Read More

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http://dx.doi.org/10.1186/s12891-018-2243-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123930PMC
September 2018
40 Reads

[Treatment of proximal femoral benign lesions by proximal femoral nail anti-rotation combined with curettage and bone graft through the Watson-Jones approach].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 07;32(7):893-898

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041,

Objective: To evaluate the feasibility and effectiveness of proximal femoral nail anti-rotation (PFNA) combined with curettage and bone graft through Watson-Jones approach in the treatment of proximal femur benign tumors and tumor like lesions.

Methods: The clinical data of 38 patients with benign tumors and tumor like lesions in the proximal femur who were treated through the Watson-Jones approach with PFNA combined with curettage and bone graft between January 2008 and January 2015 were retrospective analysed. There were 24 males and 14 females with an average age of 28 years (range, 15-57 years). Read More

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http://dx.doi.org/10.7507/1002-1892.201801128DOI Listing
July 2018
11 Reads

Total hip arthroplasty following failure of tantalum rod implantation for osteonecrosis of the femoral head with 5- to 10-year follow-up.

BMC Musculoskelet Disord 2018 08 16;19(1):289. Epub 2018 Aug 16.

Department of Orthopedic Surgery, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai West Road, Xuzhou, Jiangsu, 221002, People's Republic of China.

Background: Total hip arthroplasty (THA) with failure of tantalum rod implant for osteonecrosis of the femoral head (ONFH) will be the only choice for patients. However,it remains unknown whether tantalum rod implantation has an adverse effect on the survival time of implants following conversion to THA. The aim of this study was to retrospectively evaluate the clinical and radiographic outcomes of conversion to THA in patients who were previously treated with implantation of a tantalum rod. Read More

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https://bmcmusculoskeletdisord.biomedcentral.com/articles/10
Publisher Site
http://dx.doi.org/10.1186/s12891-018-2219-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097200PMC
August 2018
16 Reads

[Imaging and classification of avascular femoral head necrosis].

Authors:
K Bohndorf A Roth

Orthopade 2018 Sep;47(9):729-734

Bereich Endoprothetik/Orthopädie, Klinik und Poliklinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinik Leipzig AöR, Leipzig, Deutschland.

Avascular femoral head necrosis (AVNFH) is difficult to diagnose on plain radiographs in early stages of the disease. Since early stages are often clinically occult, early use of MRI is required to rule out or verify a clinical suspicion. MRI and, in some cases, additional CT are the cornerstones of AVNFH diagnosis and classification. Read More

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http://dx.doi.org/10.1007/s00132-018-3615-7DOI Listing
September 2018
15 Reads

Drilling Combined with Adipose-derived Stem Cells and Bone Morphogenetic Protein-2 to Treat Femoral Head Epiphyseal Necrosis in Juvenile Rabbits.

Curr Med Sci 2018 Apr 30;38(2):277-288. Epub 2018 Apr 30.

Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, 410013, China.

This study was designed to evaluate the effects of drilling through the growth plate and using adipose-derived stem cells (ADSCs) and bone morphogenetic protein-2 (BMP-2) to treat femoral head epiphyseal ischemic necrosis, which can be done in juvenile rabbits. Passagefour bromodeoxyuridine (BrdU)-labeled ADSCs were cultured, assayed with MTT to determine their viability and stained with alizarin red dye to determine their osteogenic ability. Two-month-old, healthy male rabbits (1. Read More

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http://dx.doi.org/10.1007/s11596-018-1876-3DOI Listing
April 2018
10 Reads

Patchy increased echogenicity: a sonographic sign of femoral head necrosis following reduction and casting for developmental dysplasia of the hip.

Pediatr Radiol 2018 12 28;48(13):1971-1974. Epub 2018 Jul 28.

Department of Orthopedic Surgery, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA.

A developmental dysplasia of the hip (DDH) case treated by closed reduction and casting and subsequently confirmed to have avascular necrosis (AVN) was retrospectively noted to have an abnormal pattern of echogenicity in the femoral head on sonograms obtained within 1.5 months of surgery. Patchy increased echogenicity in parts of the unossified cartilage replaced the normal pattern of central coalescence of vessels described with development of the ossification center. Read More

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http://dx.doi.org/10.1007/s00247-018-4212-yDOI Listing
December 2018
12 Reads

Role of FGF-2 Transfected Bone Marrow Mesenchymal Stem Cells in Engineered Bone Tissue for Repair of Avascular Necrosis of Femoral Head in Rabbits.

Cell Physiol Biochem 2018 19;48(2):773-784. Epub 2018 Jul 19.

Guizhou Medical University, Guiyang, China.

Background/aims: Avascular necrosis of the femoral head (ANFH) is the focus and difficulty of orthopedic diseases. Recently, tissue engineering bone for this disease has shown a good therapeutic effect. The aim of the present study was to investigate the therapeutic effect of basic fibroblast growth factor (FGF-2) as cytokines transfected bone marrow mesenchymal stem cells (BMSCs) in constructing tissue-engineered bone for avascular necrosis of the femoral head. Read More

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http://dx.doi.org/10.1159/000491906DOI Listing
September 2018
8 Reads
2.880 Impact Factor

The role of the subchondral layer in osteonecrosis of the femoral head: analysis based on HR-QCT in comparison to MRI findings.

Acta Radiol 2019 Apr 6;60(4):501-508. Epub 2018 Jul 6.

1 Department of Orthopedics, Medical University of Vienna, 1090 Vienna, Austria.

Background: Non-traumatic avascular osteonecrosis of the femoral head (ONFH) is a severe disease causing destruction of the hip joint, often necessitating total hip arthroplasty (THA) even in young patients. Magnetic resonance imaging (MRI) is commonly used for diagnosis of ONFH, but provides limited insight into the subchondral bone microstructure.

Purpose: To analyze routine MRI findings in comparison to high-resolution quantitative computed tomography (HR-QCT) with a special focus on the subchondral layer and to estimate the importance of differences determining the indication for THA. Read More

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http://dx.doi.org/10.1177/0284185118786070DOI Listing
April 2019
12 Reads

Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review.

J Orthop Surg Res 2018 Jul 4;13(1):167. Epub 2018 Jul 4.

Department of Orthopedics, Heibei General Hospital, No. 348 Heping East Road, Shijiazhuang, 050051, Hebei, China.

Objective: To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head.

Methods: By searching multiple databases and sources, including PubMed, Cochrane, and Embase database, by the index words updated in December 2017, qualified studies were identified and relevant literature sources were also searched. The qualified studies included prospective cohort studies and cross-sectional studies. Read More

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http://dx.doi.org/10.1186/s13018-018-0836-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031173PMC
July 2018
14 Reads

Role of Advanced Imaging in the Diagnosis and Management of Active Legg-Calvé-Perthes Disease.

J Am Acad Orthop Surg 2018 Aug;26(15):526-536

From Gillette Children's Specialty Healthcare, St. Paul, MN (Dr. Laine and Dr. Novotny), the Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN (Dr. Laine), the Division of Orthopaedic Surgery and Sports Medicine, Children's National Health System, Washington, DC (Dr. Martin), Campbell Clinic Orthopaedics, Memphis, TN (Dr. Kelly), the Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee, Memphis, TN (Dr. Kelly), and Le Bonheur Children's Hospital, Germantown, TN (Dr. Kelly).

Since the first description of Legg-Calvé-Perthes disease a century ago, the diagnosis, staging, prognosis, and treatment decisions have been based on plain radiographs. The goal of treatment is prevention of femoral head deformity, yet radiographic prognostic classifications are applied in the fragmentation stage, often after deformity occurs. These classifications are assigned too late in the progression of the disease to maximize the effects of intervention. Read More

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http://dx.doi.org/10.5435/JAAOS-D-16-00856DOI Listing
August 2018
11 Reads

Natural History of Structural Hip Abnormalities and the Potential for Hip Preservation.

J Am Acad Orthop Surg 2018 Aug;26(15):515-525

From Intermountain Healthcare, Salt Lake City, UT (Dr. Wylie), University of Utah, Salt Lake City (Dr. Peters), and University of Utah Hospital, Salt Lake City (Dr. Aoki).

Hip osteoarthritis (OA) exerts a significant burden on society, affecting 3% of Americans aged >30 years. Recent advances in the understanding of the pathoanatomy and pathomechanics of the hip have led to treatment options for young adults with hip pain. Femoroacetabular impingement, specifically cam-type femoroacetabular impingement, hip dysplasia, and the sequelae of pediatric hip disease can predispose the hip to early OA. Read More

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http://dx.doi.org/10.5435/JAAOS-D-16-00532DOI Listing
August 2018
1 Read

A CARE-compliant article: Biomechanics of treating early-stage femoral-head osteonecrosis by using a β-tricalcium phosphate bioceramic rod system: a 3-dimensional finite-element analysis.

Medicine (Baltimore) 2018 Jun;97(25):e10808

Guangxi Medical University, Nanning.

The effect of implanting a β-TCP bioceramic rod system (BRS) can be observed with using the 3-dimensional (3D) finite-element method on the biomechanics of early-stage osteonecrosis of the femoral head (ONFH), to provide a theoretical basis for the biomechanics of applying the β-TCP BRS in the treatment of ONFH.A healthy 172 cm tall male adult volunteer (age: 40 years, weight: 70 kg, and femoral diameter: 50 mm) was selected for this study. The volunteer had no history of diseases in the hip, lower back, and lower limbs. Read More

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http://dx.doi.org/10.1097/MD.0000000000010808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023943PMC
June 2018
7 Reads

A Case Report of Combined Ultrasound and Fluoroscopic-Guided Percutaneous Radiofrequency Lesioning of the Obturator and Femoral Articular Branches in the Treatment of Persistent Hip Pain in a Pediatric Patient.

Pain Pract 2019 01 9;19(1):52-56. Epub 2018 Jul 9.

Department of Anesthesiology, Perioperative, and Pain Medicine, Division of Pain Medicine, Stanford University, Palo Alto, California, U.S.A.

Hip denervation comprising radiofrequency lesioning of the obturator and femoral articular branches is used in adults with refractory hip pain who are not surgical candidates. Persistent hip pain occurs infrequently in pediatric patients, and there are limited data on the safety and efficacy of this procedure in a pediatric population. We provide a case report of a successful ultrasound and fluoroscopic-guided hip denervation procedure in an 11-year-old girl with persistent right hip pain after septic arthritis refractory to conservative and surgical management. Read More

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http://dx.doi.org/10.1111/papr.12724DOI Listing
January 2019

Avascular necrosis: a growing concern for the HIV population.

BMJ Case Rep 2018 Jun 6;2018. Epub 2018 Jun 6.

Department of Internal Medicine, University of Florida Health, Jacksonville, Florida, USA.

A 33-year-old woman with history of HIV presented with 4 months of gradually progressing right hip pain and was found to have avascular necrosis (AVN) of both femoral heads. She had no other risk factors for AVN including sickle cell disease, systemic lupus erythematosus, prolonged steroid used or trauma. She initially failed conservative management and ultimately had bilateral hip core decompressions. Read More

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http://dx.doi.org/10.1136/bcr-2017-221678DOI Listing
June 2018
9 Reads

Approach to the Hip for SCFE: The North American Perspective.

Authors:
Daniel J Sucato

J Pediatr Orthop 2018 Jul;38 Suppl 1:S5-S12

Texas Scottish Rite Hospital for Children, Department of Orthopaedics, University of Texas at Southwestern Medical Center, Dallas, TX.

The treatment of slipped capital femoral epiphysis (SCFE) in North America has seen a change over the past 15 to 20 years due to a better understanding of the blood flow supplying the femoral head, the ability to monitor the pressure/flow in real time and greater access to the deformity with the development of surgical approaches providing that access. These advances have mainly affected the treatment of the unstable SCFE to mitigate the risk of avascular necrosis but have also been utilized for the stable SCFE when severe deformity remains. This paper will provide a summary of some of the current techniques utilized in North America in the treatment of SCFE and will focus on the studies reported on this condition from this continent. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001183DOI Listing
July 2018
6 Reads

Cyclosporine use and male gender are independent determinants of avascular necrosis after kidney transplantation: a cohort study.

Nephrol Dial Transplant 2018 Nov;33(11):2060-2066

Department of Nephrology and Internal Intensive Care, Charité University Medicine Berlin, Campus Virchow-Clinic, Berlin, Germany.

Background: Kidney transplant recipients (KTRs) are at increased risk of avascular necrosis (AVN) due to bone disorder, steroid use and common comorbidities. However, knowledge on risk factors and outcomes of AVN among KTRs in the modern era of immunosuppression remains scarce.

Methods: We analysed 765 KTRs between 2001 and 2013 for AVN. Read More

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http://dx.doi.org/10.1093/ndt/gfy148DOI Listing
November 2018
1 Read

The clinical application of a novel method of internal fixation for femoral neck fractures-dynamic locking compression system.

J Orthop Surg Res 2018 May 31;13(1):131. Epub 2018 May 31.

Department of Orthopedic Surgery, China Resources & WISCO General Hospital, No. 209 Yejin Road, Wuhan, Hubei Province, China.

Background: Femoral neck fractures are the commonly encountered injury in orthopedic practice and result in significant morbidity and mortality. Currently, how to treat femoral neck fractures safely and effectively is still a challenge. The objective of this study is to evaluate the efficiency of dynamic compression locking system for femoral neck fractures. Read More

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http://dx.doi.org/10.1186/s13018-018-0827-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984372PMC
May 2018
5 Reads

Long-term outcomes following the medial approach for open reduction of the hip in children with developmental dysplasia.

Bone Joint J 2018 Jun;100-B(6):822-827

Department of Orthopedic Surgery, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands.

Aims Open reduction is required following failed conservative treatment of developmental dysplasia of the hip (DDH). The Ludloff medial approach is commonly used, but poor results have been reported, with rates of the development of avascular necrosis (AVN) varying between 8% and 54%. This retrospective cohort study evaluates the long-term radiographic and clinical outcome of dislocated hips treated using this approach. Read More

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http://dx.doi.org/10.1302/0301-620X.100B6.BJJ-2017-0670.R2DOI Listing
June 2018
2 Reads

Clinical value of 3D printing guide plate in core decompression plus porous bioceramics rod placement for the treatment of early osteonecrosis of the femoral head.

J Orthop Surg Res 2018 May 30;13(1):130. Epub 2018 May 30.

Department of Orthopaedics, Xiangya Hospital of Central South University, Changsha, People's Republic of China.

Background: The conventional method of core decompression combined with porous bioceramics rod is usually performed under C-arm fluoroscopy for the treatment of early osteonecrosis of the femoral head (ONFH). This study was to evaluate the clinical value and efficacy of three-dimensional (3D) printing guide plate in the process of core decompression plus porous bioceramics rod for the treatment of early ONFH.

Methods: Forty patients were enrolled, including 20 patients undergoing the surgery with 3D printing guide plate in the experiment group and 20 controls with C-arm fluoroscopy. Read More

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https://josr-online.biomedcentral.com/articles/10.1186/s1301
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http://dx.doi.org/10.1186/s13018-018-0812-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977560PMC
May 2018
8 Reads

[Mid-term effectiveness of large-head metal-on-metal total hip arthroplasty].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 04;32(4):389-393

Department of Orthopaedics, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, 215006, P.R.China.

Objective: To explore the mid-term effectiveness of large-head metal-on-metal total hip arthroplasty (THA).

Methods: A retrospective analysis was made on the clinical date of 40 patients (43 hips) who were treated with the large-head metal-on-metal THA between April 2009 and June 2010. There were 18 males (20 hips) and 22 females (23 hips) with an average age of 55. Read More

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http://dx.doi.org/10.7507/1002-1892.201709087DOI Listing
April 2018
10 Reads

[Short-term effectiveness analysis of one-stage bilateral total hip arthroplasty by direct anterior approach].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 09;31(9):1036-1042

Department of Orthopedics, the Affiliated Hospital of Southwest Medical University, Luzhou Sichuan, 646000,

Objective: To compare the effectiveness of one-stage bilateral total hip arthroplasty by direct anterior approach (DAA) and by posterolateral approach, and to investigate the application value of DAA in one-stage bilateral total hip arthroplasty.

Methods: The clinical data of 65 patients who underwent one-stage bilateral total hip arthroplasty by DAA or posterolateral approach between June 2010 and November 2015 were analyzed retrospectively. DAA was used in 34 cases (group A) and posterolateral approach was used in 31 cases (group B). Read More

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http://dx.doi.org/10.7507/1002-1892.201611111DOI Listing
September 2017
1 Read

Icariin Protects against Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Rats.

Cell Physiol Biochem 2018 22;47(2):694-706. Epub 2018 May 22.

Department of Radiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background/aims: Glucocorticoid (GC)-related osteonecrosis of the femoral head (ONFH) is a common complication following administration of steroids to treat many diseases. Our previous study demonstrated that icariin (ICA) might have a beneficial effect on the bone marrow mesenchymal stem cells (BMSCs) of patients with steroid-associated osteonecrosis. In this study, we investigated the underlying mechanisms of ICA associated with the potential enhancement of osteogenesis and anti-adipogenesis in GC-related ONFH. Read More

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http://dx.doi.org/10.1159/000490023DOI Listing
July 2018
8 Reads

Middle-term follow-up results of Pipkin type IV femoral head fracture patients treated by reconstruction plate and bioabsorbable screws.

Chin J Traumatol 2018 Jun 26;21(3):170-175. Epub 2018 Apr 26.

Department of Orthopaedics, West China Hospital of Sichuan University, Chengdu Sichuan, 610041, China. Electronic address:

Purpose: To investigate the mid-term curative effects of the treatment of Pipkin type IV femoral head fractures using a reconstruction plate and bioabsorbable screws and provide the evidence for clinical practice.

Methods: From February 2010 to September 2014, 21 patients with Pipkin type IV femoral head fractures were treated surgically. There were 13 males and 8 females with an average age of 41. Read More

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http://dx.doi.org/10.1016/j.cjtee.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033733PMC
June 2018
18 Reads

Pediatric Orthopaedic Consults From Chiropractic Care.

J Surg Orthop Adv Spring 2018;27(1):58-63

Department of Orthopaedics, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania.

Alternative medicine in pediatrics is expanding, with chiropractic now a common choice for families seeking alternative medical care. Currently, there is sparse information in the literature exploring the role of chiropractic in orthopaedic pathology. The objective of this case series is to present pediatric patients who received treatment from chiropractors and orthopaedic physicians as well as to review the respective existing research. Read More

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July 2018
6 Reads

COL2A1 mutation (c.3508G>A) leads to avascular necrosis of the femoral head in a Chinese family: A case report.

Mol Med Rep 2018 Jul 7;18(1):254-260. Epub 2018 May 7.

Department of Orthopedics, Second Hospital of Yueyang, Yueyang, Hunan 414000, P.R. China.

Avascular necrosis of the femoral head (ANFH) is a consequence of ischemia. Although the majority of cases of ANFH are sporadic, certain familial cases of ANFH have been reported to be associated with collagen type II α1 chain (COL2A1) mutations, which lead to COL2A1 gene dysfunction. The structure of secreted type II collagen contains a core area with a triple helical glycine (Gly)‑X‑Y domain, and the replacement of Gly in this region as a result of COL2A1 mutations may damage the structure of type II collagen. Read More

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http://dx.doi.org/10.3892/mmr.2018.8984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059677PMC

The depth of the low-intensity band on the T1-weighted MR image is useful for distinguishing subchondral insufficiency fracture from osteonecrosis of the collapsed femoral head.

Arch Orthop Trauma Surg 2018 Aug 4;138(8):1053-1058. Epub 2018 May 4.

Department of Orthopaedic Surgery, Hamanomachi Hospital, 3-3-1 Nagahama, Chuo-ku, Fukuoka, 810-8539, Japan.

Purpose: To verify the hypothesis that depth of the low-intensity band on T1-weighted MR image is useful for distinguishing subchondral insufficiency fracture (SIF) from osteonecrosis of the collapsed femoral head (ON).

Patients And Methods: We reviewed 35 consecutive hips in 35 patients with radiological evidence of subchondral collapse of the femoral head and available MR images and histology between May 2013 and January 2016. Both clinical and radiological appearances were investigated. Read More

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http://dx.doi.org/10.1007/s00402-018-2948-3DOI Listing

Three-dimensional MRI Analysis of Femoral Head Remodeling After Reduction in Patients With Developmental Dysplasia of the Hip.

J Pediatr Orthop 2018 Aug;38(7):e377-e381

Department of Orthopaedic Surgery, University of Tsukuba, Tsukuba Pediatric Orthopaedic Group, Tsukuba.

Background: Previous reports on patients with developmental dysplasia of the hip (DDH) showed that the prereduced femoral head was notably smaller and more nonspherical than the intact head, with growth failure observed at the proximal posteromedial area. We evaluated the shape of the femoral head cartilage in patients with DDH before and after reduction, with size and sphericity assessed using 3-dimensional (3D) magnetic resonance imaging (MRI).

Methods: We studied 10 patients with unilateral DDH (all female) who underwent closed reduction. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001186DOI Listing
August 2018
8 Reads

Hip Joint Contact Pressure Distribution During Pavlik Harness Treatment of an Infant Hip: A Patient-Specific Finite Element Model.

J Biomech Eng 2018 Jul;140(7)

Assistant Professor Department of Radiology and Diagnostic Imaging, University of Alberta, 2A2.41 WMC, 8440-112 Street, Edmonton, AB T6G 2B7, Canada e-mail: .

Developmental dysplasia of the hip (DDH) in infants under 6 months of age is typically treated by the Pavlik harness (PH). During successful PH treatment, a subluxed/dislocated hip is spontaneously reduced into the acetabulum, and DDH undergoes self-correction. PH treatment may fail due to avascular necrosis (AVN) of the femoral head. Read More

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http://dx.doi.org/10.1115/1.4039827DOI Listing
July 2018
11 Reads

A simple, precocious, and reliable way to assess future clinical outcome in children with Perthes disease and mild femoral head involvement: correlation between MRI with diffusion-weighted and dynamic gadolinium-enhanced subtraction and Catterall and Herring classifications.

Eur J Orthop Surg Traumatol 2018 Oct 25;28(7):1283-1290. Epub 2018 Apr 25.

Department of Pediatric Radiology, Geneva University Hospitals (HUGe), Rue Willy Donzé 6, 1211, Geneva, Switzerland.

Background: In children older than 5 years with a mild form of Legg-Calvé-Perthes disease, the outcome is difficult to predict. In this study, we retrospectively correlated gadolinium-enhanced subtracted (DGS) and diffusion (DWI) MRI findings to the radiographic assessment according to the Catterall and Herring et al. classifications and to the final score according to Stulberg et al. Read More

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http://dx.doi.org/10.1007/s00590-018-2209-8DOI Listing
October 2018
1 Read

Lesion size measurement in femoral head necrosis.

Int Orthop 2018 07 25;42(7):1585-1591. Epub 2018 Apr 25.

Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, 3737 Market Street, Suite 600, Philadelphia, PA, 19104, USA.

Background: Management of patients with early stages of osteonecrosis of the femoral head remains controversial. Uniform use of an effective method of evaluation and classification, including both stage and lesion size, would allow for comparison and would significantly improve treatment of patients. There is no consensus on how best to determine lesion size. Read More

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http://dx.doi.org/10.1007/s00264-018-3912-0DOI Listing

Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with pelvic radiotherapy in adults.

Cochrane Database Syst Rev 2018 04 23;4:CD010604. Epub 2018 Apr 23.

Radiotherapy-related Research, The Christie NHS Foundation Trust, Wilmslow Road, Manchester, Greater Manchester, UK, M20 4BX.

Background: Pelvic radiotherapy is a treatment delivered to an estimated 150,000 to 300,000 people annually across high-income countries. Fractures due to normal stresses on weakened bone due to radiotherapy are termed insufficiency fractures. Pelvic radiotherapy-related interruption of the blood supply to the hip is termed avascular necrosis and is another recognised complication. Read More

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http://dx.doi.org/10.1002/14651858.CD010604.pub2DOI Listing
April 2018
15 Reads