6,349 results match your criteria Imaging in Atrial Septal Defects

Congenitally corrected transposition of the great arteries (CCTGA).

BMJ Case Rep 2021 Jun 9;14(6). Epub 2021 Jun 9.

Department of Cardiology, Mater Dei Hospital, Msida, Malta.

A 33-year-old man presented with a 3-week history of breathlessness and cough. He disclosed that he was informed regarding a heart defect as a child in his home country but was unaware of its nature and was never followed up. Examination revealed a pansystolic murmur (loudest at the apex), a hyperdynamic, displaced apex, and pulmonary oedema. Read More

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Left ventricular restrictive physiology in kids with atrial septal defects: Something unexpected!

Ann Pediatr Cardiol 2021 Apr-Jun;14(2):228-230. Epub 2021 Apr 10.

Department of Pediatric Cardiology and Adults with Congenital Heart Disease, Evelina Children's, Hospital, St Thomas Hospital, 249 Westminster Bridge Road, SE1 7EH, London, England.

Atrial septal defect (ASD) associated with left ventricular (LV) diastolic dysfunction (DD) is rare in children. DD is common in elderly patients undergoing ASD closure. Restrictive physiology among children undergoing percutaneous ASD closure is something unexpected that has not been described before in the literature. Read More

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Case report of worsening of preexisting pericardial effusion after ASD device closure: is it calamitous?

Egypt Heart J 2021 Jun 5;73(1):50. Epub 2021 Jun 5.

Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Secundum-type atrial septal defects (ASD) constitute 8% to 10% of congenital heart defect. Secundum ASDs can be closed either percutaneously or surgically. However, ASD device closure has proven to be technically safe and feasible; it is not free of complications. Read More

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Platypnoea-orthodeoxia syndrome: the importance of the patient's posture for diagnosis.

BMJ Case Rep 2021 Jun 2;14(6). Epub 2021 Jun 2.

Cardiology, Centro Hospitalar Universitário do Porto EPE, Porto, Portugal.

Platypnoea-orthodeoxia syndrome (POS) is a rare condition characterised by the association of dyspnoea and arterial oxygen desaturation induced by standing and relieved by recumbency. The precise mechanism remains poorly understood, but it appears to involve both anatomical and functional components producing a significant right-to-left shunting under certain postural conditions. This syndrome is associated with either intracardiac or extracardiac aetiologies, and the diagnosis depends on high clinical suspicion. Read More

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Massive pulmonary embolism with a large thrombus stuck in patent foramen ovale - an impending paradoxical embolism.

Vnitr Lek 2021 ;67(2):114-118

Patent foramen ovale is a persisting communication between the left and right atrium, present in approximately 25% of population, usually asymptomatic. Under normal conditions there is either no blood flow or a hemodynamically nonsignificant left-to-right shunt between the atria. However, increased right atrium pressure, as it is in pulmonary embolism, can make PFO a right-to-left shunt and poses a risk of paradoxical systemic embolism, including the risk of ischemic stroke. Read More

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Determinants of in-hospital death in patients with a thrombus straddling a patent foramen ovale: protocol of a systematic review.

F1000Res 2020 10;9:1437. Epub 2020 Dec 10.

Heart & Brain Laboratory, Western University, London, Ontario, N6C1C4, Canada.

Thrombi identified on echocardiography at the time of straddling a patent foramen ovale (PFO) constitute a medical emergency with an associated imminent risk of death.  Ischemic stroke (IS) and myocardial infarction (MI) occurring in patients with a thrombus straddling a PFO (TSPFO) may be associated with increased risk of in-hospital death. Variables associated with increased risk of death in women and men may be different. Read More

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Coronary sinus atrial septal defects in adults over the past 20 years at new Tokyo hospital: case series.

J Cardiothorac Surg 2021 May 29;16(1):150. Epub 2021 May 29.

New Tokyo Hospital, 1271 Wanagaya, Matsudo, Chiba, 270-2232, Japan.

Background: An isolated coronary sinus (CS) atrial septal defect (ASD) is defined as a CS unroofed in the terminal portion without a persistent left superior vena cava or other anomalies. This defect is rare and part of the wide spectrum of unroofed CS syndrome (URCS). Recently, several reports have described this finding. Read More

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[Feasibility and safety of intracardiac ultrasound-assisted atrial septal puncture during radiofrequency ablation for atrial fibrillation].

Zhonghua Xin Xue Guan Bing Za Zhi 2021 May;49(5):474-478

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, Beijing 100029, China.

To explore the feasibility and safety of intracardiac ultrasound-assisted atrial septal puncture (ASP) during radiofrequency ablation for atrial fibrillation. We enrolled 241 consecutive patients scheduled to radiofrequency ablation for atrial fibrillation in Beijing Anzhen Hospital from July to September 2020. Inclusion criteria: patients aged over 18 years with a clear electrocardiogram record of atrial fibrillation. Read More

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Preliminary Investigation of In situ Thrombus Within Patent Foramen Ovale in Patients With and Without Stroke.

Chaowu Yan Hua Li

JAMA 2021 05;325(20):2116-2118

Department of Cardiology, Beijing Tongren Hospital, Beijing, China.

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Cerebral paradoxical embolisation in a patient with cystic fibrosis with patent foramen ovale: a comparative review of literature.

BMJ Case Rep 2021 May 24;14(5). Epub 2021 May 24.

Interventional Cardiology, Gill Heart and Vascular Institute, University of Kentucky, Lexington, Kentucky, USA.

A 52-year-old woman with cystic fibrosis presented to the emergency department with expressive aphasia and right-sided hemiparesis. CT scan of the brain revealed a left middle cerebral artery territory infarct. A diagnosis of cerebral paradoxical embolisation associated with patent foramen ovale and a history of deep venous thrombosis was made. Read More

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TARP syndrome associated with renal malformation and optic nerve atrophy.

BMJ Case Rep 2021 May 24;14(5). Epub 2021 May 24.

Department of Pediatrics at Fundación Santa Fé de Bogotá, Hospital Universitario de la Fundacion Santa Fe de Bogota, Bogota, Colombia.

Talipes equinovarus, atrial septal defect, Robin sequence and persistent left superior vena cava (TARP) syndrome is a congenital disease caused by mutations in the RBBM10 gene. It has a low prevalence and a high rate of mortality in the neonatal stage. In this case report, we present a case of a 32-week gestational age preterm newborn with a prenatal diagnosis of intrauterine growth restriction, with a persistent left superior vena cava, interatrial communication and a horseshoe kidney. Read More

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Design of heart phantoms for ultrasound imaging of ventricular septal defects.

Int J Comput Assist Radiol Surg 2021 May 21. Epub 2021 May 21.

Interventional Imaging Lab, Department of Software and IT Engineering, École de technologie supérieure, 1100 Notre-Dame West, Montreal, H3C 1K3, Canada.

Purpose: Ventricular septal defects (VSDs) are common congenital heart malformations. Echocardiography used during VSD hybrid cardiac procedures requires extensive training for image acquisition and interpretation. Cardiac surgery simulators with heart phantoms have shown usefulness for such training, but they are limited in visualization and characterization of complex VSD. Read More

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[Paradox embolism in a patient with pulmonary embolism and unknown patent foramen ovale].

Ugeskr Laeger 2021 04;183(15)

This case report describes a 64-year-old male patient, who presented with sudden onset dyspnoea. A chest CT-angiography revealed the presence of central bilateral pulmonary embolisms (PE), and he was admitted for anticoagulative treatment. Shortly after admission, he developed discomfort and pulselessness in the right leg, and a limb CT-angiography revealed a femoral artery thrombus. Read More

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Peripheral thrombosis causing simultaneous saddle pulmonary embolism and paradoxical ST elevation myocardial infarction resulting in cardiovascular collapse.

BMJ Case Rep 2021 Apr 21;14(4). Epub 2021 Apr 21.

Department of Cardiology, St Vincent Hospital, Worcester, Massachusetts, USA.

Paradoxical coronary artery embolism is often an underdiagnosed cause of acute myocardial infarction (MI). It should always be considered in patient with acute MI and a low risk profile for atherosclerotic coronary artery disease. We describe a patient with simultaneous acute saddle pulmonary embolism (PE) and acute ST segment elevation MI due to paradoxical coronary artery embolism. Read More

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Patent foramen ovale revealed by COVID-19 pneumonia.

BMC Pulm Med 2021 Apr 19;21(1):126. Epub 2021 Apr 19.

Department of Pneumology, CHU Erasme Hospital, Université Libre de Bruxelles, Bruxelles, Belgium.

Background: Platypnea-orthodeoxia syndrome (POS) is a rare condition characterized by dyspnoea (platypnea) and arterial desaturation in the upright position resolved in the supine position (orthodeoxia). Intracardiac shunt, pulmonary ventilation-perfusion mismatch and others intrapulmonary abnormalities are involved.

Case Presentation: We report a case of POS associated with two pathophysiological issues: one, cardiac POS caused by a patent foramen ovale (PFO) and second, pulmonary POS due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interstitial pneumonia. Read More

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COVID-19-Positive Patient and Hypoxemia: Are Lungs Always to Be Blamed?

JACC Cardiovasc Interv 2021 05 14;14(9):e101-e102. Epub 2021 Apr 14.

Section of Cardiology, Cardiac Sciences Program, St Boniface Hospital, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

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Management of straddling thrombus through patent foramen ovale complicating pulmonary embolism.

BMJ Case Rep 2021 Apr 13;14(4). Epub 2021 Apr 13.

Intensive Care Unit, Nepean Hospital ICU, Kingswood, New South Wales, Australia.

A 60-year-old man was admitted to intensive care unit with the diagnosis of pulmonary embolism. Bedside transthoracic echocardiography revealed the extension of the thrombus into left atrium and ventricle through patent foramen ovale (PFO). A straddling thrombus also described as impending paradoxical embolism is a rare condition when thrombus embolised to the heart gets caught in PFO. Read More

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Comment on "Concomitant fat embolism syndrome and pulmonary embolism in a patient with patent foramen ovale".

Acta Orthop Traumatol Turc 2021 03;55(2):189-190

Department of Underwater and Hyperbaric Medicine, İstanbul University, İstanbul School of Medicine, İstanbul, Turkey.

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De Novo mutation of FOXF1 causes alveolar capillary dysplasia with misalignment of pulmonary veins: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25375

Department of Cardiology, Kunming Children's Hospital, Kunming, Yunnan.

Rationale: Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) is a rare congenital malformation in neonates that results in severe respiratory distress and pulmonary hypertension. ACD/MPV is caused by mutations in the FOXF1 gene. Herein, a new case of a girl with ACD/MPV carrying a novel pathogenic variant of FOXF1 was reported. Read More

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Major clinical impact of patent foramen ovale after HeartMate3 implantation: periprocedural diagnosis and its pitfalls.

BMJ Case Rep 2021 Apr 1;14(4). Epub 2021 Apr 1.

Cardiology, Centro Hospitalar de Lisboa Ocidental EPE Hospital de Santa Cruz, Carnaxide, Portugal.

We report a clinically significant right-to-left intracardiac shunt through a patent foramen ovale, diagnosed during investigations for hypoxemia and left ventricular dilation on the late postoperative period of a HeartMate3 implantation. We discuss diagnostic pitfalls and haemodynamic influences in this scenario, as well as the possibility of successful percutaneous treatment. Read More

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The Prognostic Value of Right Atrial Strain Imaging in Patients with Precapillary Pulmonary Hypertension.

J Am Soc Echocardiogr 2021 Mar 24. Epub 2021 Mar 24.

Division of Cardiology, Washington University in St. Louis, St. Louis, Missouri; Penn State University College of Medicine, Hershey Medical Center, Hershey, Pennsylvania. Electronic address:

Background: Right ventricular (RV) failure in patients with pulmonary hypertension (PH) is associated with unfavorable clinical events and a poor prognosis. Elevation of right atrial (RA) pressure is established as a marker for RV failure. However, the additive prognostic value of RA mechanical function is unclear. Read More

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Decompression sickness after a highly conservative dive in a diver with known persistent foramen ovale: Case report.

Diving Hyperb Med 2021 Mar;51(1):111-115

Tritonia Scientific Ltd., Oban, Scotland.

A diver returned to diving, 15 months after an episode of neuro-spinal decompression sickness (DCS) with relapse, after which she had been found to have a moderate to large provoked shunt across a persistent (patent) foramen ovale (PFO), which was not closed. She performed a single highly conservative dive in line with the recommendations contained in the 2015 position statement on PFO and diving published jointly by the South Pacific Underwater Medicine Society and the United Kingdom Sports Diving Medical Committee. An accidental Valsalva manoeuvre shortly after surfacing may have provoked initial symptoms which later progressed to DCS. Read More

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Echocardiography - techniques and pitfalls whilst diagnosing persistent (patent) foramen ovale as a risk factor in divers with a history of decompression sickness.

Diving Hyperb Med 2021 Mar;51(1):98-102

Mater Dei Hospital, Malta.

The case of a diver with a history of decompression sickness (DCS) after recreational scuba diving is presented. Cutis marmorata, a subtype of cutaneous DCS, has been consistently associated with the presence of a persistent (patent) foramen ovale (PFO) as a risk factor. Diagnostic uncertainty arose when transthoracic echocardiography with antecubital injection of agitated saline bubbles (ASBs) did not show any significant shunt, but the presence of a large Eustachian valve was counteracted by intra-femoral injection of ASBs, showing a large PFO with spontaneous shunting. Read More

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Abnormal Left-Hemispheric Sulcal Patterns in Adults With Simple Congenital Heart Defects Repaired in Childhood.

J Am Heart Assoc 2021 Apr 22;10(7):e018580. Epub 2021 Mar 22.

Department of Clinical Medicine Aarhus University Aarhus N Denmark.

Background Children operated on for a simple congenital heart defect (CHD) are at risk of neurodevelopmental abnormalities. Abnormal cortical development and folding have been observed in fetuses with CHD. We examined whether sulcal folding patterns in adults operated on for simple CHD in childhood differ from those of healthy controls, and whether such differences are associated with neuropsychological outcomes. Read More

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Atrio-aortic erosion caused by Amplatzer Atrial Septal Occluder - a case report.

J Cardiothorac Surg 2021 Mar 20;16(1):36. Epub 2021 Mar 20.

Department of Cardiac Surgery, LMU University Hospital, Marchioninistrasse 15, 81377, Munich, Germany.

Background: In specialized centers, percutaneous closure using specific occluders is the first-choice treatment in atrial septal defects (ASD). Late complications after this intervention, such as erosion of the aorta or the atria, are rare and have not been sufficiently approached and dealt with in literature. In our clinic we have been faced with the problematic situation of diagnosing and treating such cases. Read More

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Comparing the diagnostic value of Echocardiography In Stroke (CEIS) - results of a prospective observatory cohort study.

BMC Neurol 2021 Mar 17;21(1):118. Epub 2021 Mar 17.

Department for Neurology, University Medical Center Göttingen, Robert-Koch Straße 40, 37075, Göttingen, Germany.

Background: Echocardiography is one of the main diagnostic tools for the diagnostic workup of stroke and is already well integrated into the clinical workup. However, the value of transthoracic vs. transesophageal echocardiography (TTE/TEE) in stroke patients is still a matter of debate. Read More

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Antiphospholipid syndrome leading to paradoxical embolus and stroke via secundum atrial septal defect.

BMJ Case Rep 2021 Mar 16;14(3). Epub 2021 Mar 16.

Stroke Medicine, NHS Tayside, Dundee, UK.

We have presented a case of a 22-year-old man, presenting with cerebral infarct, subsequently found to have antiphospholipid syndrome (APS), deep venous thrombosis, pulmonary embolism and atrial septal defect (ASD), thereby confirming the presence of infarct due to paradoxical embolism in this patient. The importance of ASD in the patients of APS, resulting in paradoxical embolism is debatable, with recent studies undermining its importance. We have demonstrated that it does indeed happen. Read More

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A large congenital atrial septal defect in an adult with delayed therapy.

J Int Med Res 2021 Mar;49(3):300060521997700

Department of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.

Patients with a large congenital atrial septal defect (ASD) traditionally have the ASD repaired at the preschool age. Unfortunately, insufficient education of patients regarding medical science and clinical recommendations can lead to delayed therapy, resulting in complications during adulthood. We report a rare case of a large congenital ASD in a 20-year-old man. Read More

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Iatrogenic atrial septal defect after percutaneous left atrial appendage closure: a single-center study.

Int J Cardiovasc Imaging 2021 Mar 14. Epub 2021 Mar 14.

Cardiology Department, Centro Hospitalar e universitário de Coimbra - Hospital Geral, Quinta dos Vales - São Martinho do Bispo, 3043-853, Coimbra, Portugal.

There is conflicting evidence regarding the significance of iatrogenic atrial septal defects (iASDs) after transseptal puncture during percutaneous cardiac interventions. To study the clinical outcome of iASD after percutaneous left atrial appendage occlusion (LAAo). Single-center, retrospective study of 70 consecutive patients who underwent percutaneous LAAo between May 2010 and August 2017, and subsequent transesophageal echocardiography (TEE) at 1 month. Read More

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