646 results match your criteria Imaging in Arteriovenous Lung Malformation


Synchronous cerebral arteriovenous malformation and lung adenocarcinoma carcinoma brain metastases: A case study and literature review.

Neurochirurgie 2019 Feb 9;65(1):36-39. Epub 2019 Jan 9.

Department of Surgery, Division of Neurosurgery, University of Connecticut Health, Farmington, Connecticut, 06032, USA. Electronic address:

Introduction: While there are numerous published cases of arteriovenous malformations (AVMs) developing in the setting of malignancy, it is extremely rare to find them concurrently associated in the brain.

Clinical Case: This is the case of a 55-year-old male who presented to the emergency department complaining of headaches, memory and visual changes. Neuro-imaging revealed a right temporal parietal AVM and an adjoining hyperenhancing occipitotemporal lobe lesion with concern for a possible evolving stroke. Read More

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http://dx.doi.org/10.1016/j.neuchi.2018.07.003DOI Listing
February 2019
1 Read

Complex pulmonary arteriovenous fistula in mother and daughter: Case report.

Medicine (Baltimore) 2019 Jan;98(2):e13922

Department of Cardiology, West China Hospital, Sichuan University, Chengdu.

Rationale: Complex pulmonary arteriovenous fistula (PAVF) is unusual, and even rarer in 2 members of a family. PAVF may not appear on chest X-ray or computed tomography imaging, especially in asymptomatic patients, and therapy is limited. Herein, PAVFs occurring in a mother and daughter are described, with the current standard methods of diagnosis and treatment of PAVF. Read More

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http://dx.doi.org/10.1097/MD.0000000000013922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336614PMC
January 2019
4 Reads

Absence of renal phenotype in hereditary haemorrhagic telangiectasia.

Intern Med J 2018 Oct;48(10):1255-1257

Department of Genomic Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Hereditary haemorrhagic telangiectasia is characterised by abnormal blood vessel formation, producing telangiectasia and arteriovenous malformations in multiple organs. Information regarding possible renal involvement in hereditary haemorrhagic telangiectasia is limited. This study assessed renal structure and function in 11 patients with genetically confirmed diagnosis and known arteriovenous malformations in lung, liver, gastrointestinal tract or brain. Read More

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http://doi.wiley.com/10.1111/imj.14059
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http://dx.doi.org/10.1111/imj.14059DOI Listing
October 2018
6 Reads

Acquired Transpleural Systemic Artery-to-Pulmonary Artery Communication Mimicking a Pulmonary Arteriovenous Malformation and Causing a False-Positive Diagnosis of a Pulmonary Embolus.

J Vasc Interv Radiol 2018 09;29(9):1313-1315

Imaging Department, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jvir.2017.12.016DOI Listing
September 2018

Where is the Origin of the Last Normal Branch from Feeding Artery of Pulmonary Arteriovenous Malformations?

Cardiovasc Intervent Radiol 2018 Dec 22;41(12):1849-1856. Epub 2018 Aug 22.

Department of Radiology, Oita University Faculty of Medicine, 1-1 Idaigaoka Hasama-machi, Yufu-shi, Oita, 879-5593, Japan.

Purpose: Reperfusion via pulmonary-to-pulmonary arterial anastomoses is known as one type of recurrence of pulmonary arteriovenous malformations (PAVMs) after embolization. It is important to occlude the fistulous portion beyond the origin of the last normal branch from feeding artery of PAVMs to prevent recurrence. In this study, we evaluate the origin of the last normal branch by CT as well as its visibility on pulmonary arteriography (PAG). Read More

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http://dx.doi.org/10.1007/s00270-018-2063-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244990PMC
December 2018

Woman in her 50s with shortness of breath on exertion.

Heart 2019 01 9;105(2):110. Epub 2018 Aug 9.

Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Clinical Introduction: A 59-year-old woman visited an outpatient cardiology clinic due to shortness of breath on exertion. Physical examination showed no significant abnormality of vital signs. A III/VI systolic murmur was heard on the fourth intercostal space at the right sternal border. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-313655DOI Listing
January 2019
10 Reads

Patent Foramen Ovale and Hypoxemia.

Cardiol Rev 2019 Jan/Feb;27(1):34-40

Department of Cardiology, University Hospital of Bern, Bern, Switzerland.

Patent foramen ovale (PFO), an embryonic remnant of the fetal circulation, is present in 20-25% of adults. Although recent observational studies and clinical trials have established the link between PFO-mediated right-to-left shunting with cryptogenic stroke and migraine with aura, the role of a PFO in exacerbating hypoxemic medical conditions (ie, sleep apnea, chronic obstructive pulmonary disease, pulmonary hypertension, platypnea-orthodeoxia, pulmonary arteriovenous malformation, high-altitude pulmonary edema, and exercise desaturation) remains less understood. PFO-mediated hypoxemia occurs when deoxygenated venous blood from the right atrium enters and mixes with oxygenated arterial blood in the left atrium. Read More

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http://dx.doi.org/10.1097/CRD.0000000000000205DOI Listing
March 2019
17 Reads
2.410 Impact Factor

Utility of second-generation single-energy metal artifact reduction in helical lung computed tomography for patients with pulmonary arteriovenous malformation after coil embolization.

Jpn J Radiol 2018 Apr 10;36(4):285-294. Epub 2018 Feb 10.

Department of Radiology, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama-city, 700-8558, Okayama, Japan.

Purpose: The quality of images acquired using single-energy metal artifact reduction (SEMAR) on helical lung computed tomography (CT) in patients with pulmonary arteriovenous malformation (PAVM) after coil embolization was retrospectively evaluated.

Materials And Methods: CT images were reconstructed with and without SEMAR. Twenty-seven lesions [20 patients (2 males, 18 females), mean age 61. Read More

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http://link.springer.com/10.1007/s11604-018-0723-6
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http://dx.doi.org/10.1007/s11604-018-0723-6DOI Listing
April 2018
9 Reads

Hereditary haemorrhagic telangiectasia in pregnancy: regional and general anaesthesia.

Int J Obstet Anesth 2018 02 13;33:84-86. Epub 2017 Nov 13.

Respiratory Department, Royal Infirmary of Edinburgh, 51 Little France Dr, Edinburgh, UK.

Hereditary haemorrhagic telangiectasia, also known as Osler-Weber-Rendu disease, is a rare autosomal dominant multisystem disorder, characterised by mucocutaneous telangiectases and arteriovenous malformations affecting any organ. The physiological changes in pregnancy pose significant obstetric and anaesthetic challenges for women affected by the disease. The optimal timing and mode of delivery requires careful consideration; and the benefits and risks of both regional and general anaesthetic techniques must be carefully considered, depending on the organs affected. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0959289X173029
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http://dx.doi.org/10.1016/j.ijoa.2017.11.002DOI Listing
February 2018
4 Reads

Echocardiography Grading for Pulmonary Arteriovenous Malformation Screening in Children with Hereditary Hemorrhagic Telangiectasia.

J Pediatr 2018 04 20;195:288-291.e1. Epub 2017 Dec 20.

University of Toronto, Toronto, Ontario, Canada; Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Translational Medicine, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:

Transthoracic contrast echocardiography (TTCE) has high sensitivity but low specificity in screening for pulmonary arteriovenous malformations (pAVMs) in children with hereditary hemorrhagic telangiectasia (HHT). Here we describe characteristics of TTCE that might be used to reduce the need for confirmatory computed tomography scans in children with HHT. Read More

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http://dx.doi.org/10.1016/j.jpeds.2017.11.047DOI Listing
April 2018
51 Reads

Unusual synchronous liver and brain abscesses infected by rare Aerococcus viridians in a patient with pulmonary arteriovenous malformations on FDG PET/CT: A case report and literature review.

Medicine (Baltimore) 2017 Dec;96(49):e9048

aThe First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou, ZhejiangbKey Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province, Hangzhou, China.

Rationale: Pulmonary arteriovenous malformations (PAVMs) complicated with multiple organ abscesses is an uncommon manifestation. Because of the low incidence of the disease, F-18 fluorodeoxyglucose positron emission tomography with computed tomography (F-FDG PET/CT) imaging studies for PAVMs complicated with multiple organ abscesses are scarce.

Patient Concerns: We report a case of a 54-year-old man presenting with PAVMs complicated with synchronous multiple organ abscesses founded by F-FDG PET/CT. Read More

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http://dx.doi.org/10.1097/MD.0000000000009048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728921PMC
December 2017
7 Reads

Characterization of pulmonary arteriovenous malformations in ACVRL1 versus ENG mutation carriers in hereditary hemorrhagic telangiectasia.

Genet Med 2018 Jun 19;20(6):639-644. Epub 2017 Oct 19.

Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

PurposePulmonary arteriovenous malformations (pAVMs) are major contributors to morbidity and mortality in hereditary hemorrhagic telangiectasia (HHT). Mutations in ENG and ACVRL1 underlie the vast majority of clinically diagnosed cases. The aims of this study were to characterize and compare the clinical and morphologic features of pAVMs between these two genotype groups. Read More

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http://dx.doi.org/10.1038/gim.2017.160DOI Listing
June 2018
36 Reads

Pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia: Correlations between computed tomography findings and cerebral complications.

Eur Radiol 2018 Mar 10;28(3):1338-1344. Epub 2017 Oct 10.

Hospices Civils de Lyon, Hôpital Cardiologique Louis Pradel, Département d'Imagerie Cardiaque et Thoracique, Diagnostique et Interventionnelle, 59 Boulevard Pinel, 69500, Bron, France.

Objectives: Computed tomography (CT) is the modality of choice to characterise pulmonary arteriovenous malformations (PAVMs) in patients with hereditary haemorrhagic telangiectasia (HHT). Our objective was to determine if CT findings were associated with frequency of brain abscess and ischaemic stroke.

Methods: This retrospective study included patients with HHT-related PAVMs. Read More

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http://dx.doi.org/10.1007/s00330-017-5047-xDOI Listing
March 2018
10 Reads

Recurrent Cerebral Hemorrhage in Normal Pregnancy Secondary to Mycotic Pseudoaneurysms Related to Choriocarcinoma.

World Neurosurg 2018 Jan 5;109:247-250. Epub 2017 Oct 5.

Houston Methodist Neurological Institute, Texas Medical Center, Houston, Texas, USA.

Background: Choriocarcinoma coexisting with or after normal pregnancy is extremely rare. To our knowledge, our case report is the first time cerebral mycotic pseudoaneurysms from choriocarcinoma have been proven angiographically.

Case Description: A 38-week pregnant 26-year-old woman presented with an acute left frontal hemorrhage. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.09.187DOI Listing
January 2018
18 Reads

Can the "pine-needle sign" on computed tomography be used to differentiate pulmonary arteriovenous malformation from its mimics? Analysis based on dynamic contrast-enhanced chest computed tomography in adults.

Eur J Radiol 2017 Oct 31;95:314-318. Epub 2017 Aug 31.

Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. Electronic address:

Objectives/purpose: To determine the diagnostic value of morphological features on computed tomography (CT) in the differentiation of pulmonary arteriovenous malformation (pAVM) and its mimics.

Materials And Methods: We retrospectively examined 59 consecutive patients (109 lesions) with initially suspected or occult pAVM who underwent contrast-enhanced chest CT from January 2006 to June 2016. All lesions were divided into two groups based on their diagnosis: AVM (n=93) and non-AVM (n=16). Read More

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http://dx.doi.org/10.1016/j.ejrad.2017.08.032DOI Listing
October 2017
18 Reads

Systemic Artery to Pulmonary Vein Fistula After Right Upper Lobectomy Demonstrated by 4-Dimensional Flow Magnetic Resonance Imaging.

Ann Thorac Surg 2017 Aug;104(2):e169-e171

Department of Thoracic Surgery, Paris Descartes University, Georges Pompidou European Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Sorbonne Paris Cité University, Paris Descartes University, Paris, France. Electronic address:

Postoperative systemic artery to pulmonary vein fistula is very rare. In this report, we describe an exceptional condition of both intrapulmonary arteriovenous fistula and systemic artery to pulmonary vein fistula, involving all right hemithoracic systemic arteries, inducing left-to-left shunt. This condition was responsible for heart failure, 24 years after a right upper lobectomy for inflammatory tumor. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2017.02.061DOI Listing
August 2017
13 Reads

Dieulafoy's disease of the bronchial tree: a case report.

Sao Paulo Med J 2017 Jul-Aug;135(4):396-400. Epub 2017 May 29.

MD. Resident of General Surgery, Iran University of Medical Sciences, Rasool Akram Hospital, Shahrara, Tehran, Iran.

Context:: Dieulafoy's disease of the bronchial tree is a very rare condition. Few cases have been reported in the literature. It can be asymptomatic or manifest with massive hemoptysis. Read More

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http://dx.doi.org/10.1590/1516-3180.2016.0258191116DOI Listing
October 2017
10 Reads

Hepatopulmonary syndrome with large pulmonary arteriovenous malformations: CT findings with emphasis on its association with a mosaic pattern of the lung parenchyma.

Rev Esp Enferm Dig 2017 May;109(5):369

Hospital Universitario Ramón y Cajal.

We present a case of a 54-year-old patient with cirrhosis, progressive dyspnea, and platypnea. Thoracic computed tomography (CT) showed multiple pulmonary arteriovenous malformations (PAVM), confirming the diagnosis of hepatopulmonary syndrome (HPS). Besides precisely identifying the number and location of PAVM, CT also demonstrated a striking mosaic pattern of the lung parenchyma, characterized by the presence of alternating geographic areas of low attenuation (showing pulmonary vessels with a decreased diameter) with regions of relatively increased attenuation (showing pulmonary vessels with a normal diameter). Read More

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May 2017
10 Reads

Coil Intrabronchial Migration in an Arteriovenous Malformation Patient Treated 10 Years Ago.

Ann Thorac Cardiovasc Surg 2017 Aug 28;23(4):200-202. Epub 2017 Apr 28.

Department of General Thoracic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Kagoshima, Japan.

A 56-year-old male who had received transcatheter coil deposition 10 years ago for an arteriovenous malformation (AVM) was admitted to our hospital because of persistent hemosputum. Chest radiograph and bronchoscopy revealed straightened coil bundles in his air way. Recently, less invasive transcatheter intervention has been performed more frequently for treatment of AVM than surgical resection. Read More

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https://www.jstage.jst.go.jp/article/atcs/23/4/23_cr.16-0025
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http://dx.doi.org/10.5761/atcs.cr.16-00250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569255PMC
August 2017
4 Reads

Transarterial embolization of intralobar pulmonary sequestration in a young adult with hemoptysis.

J Thorac Dis 2017 Mar;9(3):E188-E193

Department of Medical Imaging, Western University, Victoria Hospital, London Health Sciences Centre, London, Ontario N6A 5W9, Canada.

Intralobar pulmonary sequestration is a rare congenital malformation characterized by the presence of dysplastic lung that does not communicate with the tracheobronchial tree, and has aberrant systemic arterial supply. While most are asymptomatic, they rarely can present with hemoptysis, which has been traditionally managed with surgical resection of the sequestration. We report a case of an 18-year-old male who presented with acute large-volume hemoptysis on a background of recurrent minor episodes of hemoptysis, due to intralobar sequestration. Read More

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http://dx.doi.org/10.21037/jtd.2017.02.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394002PMC
March 2017
2 Reads

Effect of pulmonary arteriovenous malformations on the mechanical properties of the lungs.

BMC Pulm Med 2017 04 19;17(1):64. Epub 2017 Apr 19.

Consultation Pluridisciplinaire Maladie de Rendu Osler, Université de Versailles SQY, APHP, Hôpital Ambroise Paré, Boulogne-Billancourt, France.

Background: Pulmonary arteriovenous malformations (PAVMs) are present in approximately 15-50% individuals with hereditary hemorrhagic telangiectasia (HHT). They may be isolated but more often are multiple. The goal of this study was to evaluate the influence of PAVMs on lung mechanical properties. Read More

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http://dx.doi.org/10.1186/s12890-017-0411-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395778PMC
April 2017
12 Reads

Pulmonary Arteriovenous Malformation Detected by Three-dimensional Computed Tomographic Angiography.

Heart Lung Circ 2017 Aug 22;26(8):e59-e61. Epub 2017 Mar 22.

Department of the Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.hlc.2017.02.016DOI Listing
August 2017
3 Reads

Hereditary hemorrhagic telangiectasia patient presenting with brain abscess due to silent pulmonary arteriovenous malformation.

Pan Afr Med J 2016 11;25:145. Epub 2016 Nov 11.

Department of Neurosurgery, University of Athens Medical School, "Evangelismos" General Hospital, Athens, Greece.

Hereditary hemorrhagic telangiectasia is a rare autosomal dominant inherited disease that is usually complicated by visceral vascular malformations. Patients harboring such malformations are at increased risk of brain abscess formation, which despite advances in diagnostic and surgical methods remains a life threatening medical emergency with high mortality and morbidity rates. In the present report we describe a case of cerebral abscess due to silent pulmonary arteriovenous malformation (AVM) in a young patient previously undiagnosed for hereditary hemorrhagic telangiectasia syndrome (HHT). Read More

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http://dx.doi.org/10.11604/pamj.2016.25.145.11010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326030PMC
April 2017
10 Reads

Indicators of Lung Shunt Fraction Determined by Technetium-99 m Macroaggregated Albumin in Patients with Hepatocellular Carcinoma.

Cardiovasc Intervent Radiol 2017 Aug 9;40(8):1213-1222. Epub 2017 Mar 9.

Section of Interventional Radiology, Department of Radiology, Northwestern Memorial Hospital, Robert H. Lurie Comprehensive Cancer Center, 676 N. St. Clair Street, Suite 800, Chicago, IL, USA.

Purpose: To determine the correlation of pre-procedural and imaging characteristics with lung shunt fraction (LSF) measured by technetium-99 m macroaggregated albumin (Tc-MAA) scan in patients with hepatocellular carcinoma.

Methods: A retrospective study was conducted of 428 subjects with hepatocellular carcinoma from 2004 to 2011 assessed for lung shunting by Tc-MAA scan. Baseline characteristics included age, gender, ethnicity, tumor burden, maximum dimension, number of lesions, presence of extrahepatic metastases, macrovascular (hepatic and portal vein) invasion, ascites on imaging, laboratory values, and alpha-fetoprotein (AFP). Read More

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http://dx.doi.org/10.1007/s00270-017-1619-zDOI Listing
August 2017
44 Reads

Hemoglobin Is a Vital Determinant of Arterial Oxygen Content in Hypoxemic Patients with Pulmonary Arteriovenous Malformations.

Ann Am Thorac Soc 2017 Jun;14(6):903-911

5 Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, United Kingdom.

Rationale: Pa and Sa are commonly measured in respiratory practice, but arterial oxygen content (Ca) refers to the volume of oxygen delivered to the tissues per unit blood volume. Ca is calculated from Sa and the hemoglobin concentration in blood, recognizing that each gram of hemoglobin can transport approximately 1.34 ml of oxygen when fully saturated. Read More

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http://dx.doi.org/10.1513/AnnalsATS.201611-872OCDOI Listing
June 2017
13 Reads

Surgical treatment of pulmonary arteriovenous malformations.

Turk J Med Sci 2017 Feb 27;47(1):161-166. Epub 2017 Feb 27.

Department of Thoracic Surgery, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.

Background/aim: Pulmonary arteriovenous malformations (PAVMs) are direct communications between the branches of pulmonary arteries and veins. This study evaluates surgically treated cases of pulmonary arteriovenous malformations.

Materials And Methods: We retrospectively examined 41 cases of PAVM that were operated in our clinic between 1995 and 2012. Read More

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http://dx.doi.org/10.3906/sag-1509-30DOI Listing
February 2017
11 Reads

Non-invasive CT screening for pulmonary arteriovenous malformations in children with confirmed hereditary hemorrhagic telangiectasia: Results from two pediatric centers.

Pediatr Pulmonol 2017 05 6;52(5):642-649. Epub 2017 Feb 6.

Service de Pédiatrie, Centre Hospitalier Intercommunal de Créteil, Créteil 94000, France.

Background: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder that is caused by mutations in mainly two genes, that is ENG, encoding endoglin (HHT1), or ACVRL1, encoding activin receptor-like kinase 1 (ALK-1/HHT2). HHT is characterized by recurrent epistaxis, mucocutaneous telangiectasia, and vascular visceral dysplasia responsible for visceral arteriovenous malformations (AVM).

Aim: to report the experience of two university hospitals (Trousseau, Paris, and CHIC, Creteil) with screening children for HHT and pulmonary AVM (PAVM) using high resolution computed tomography (HRCT). Read More

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http://dx.doi.org/10.1002/ppul.23649DOI Listing
May 2017
60 Reads

Gestational choriocarcinoma with renal and pulmonary metastases lacking a primary uterine origin.

Taiwan J Obstet Gynecol 2016 Dec;55(6):881-885

Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address:

Objective: We describe a case of gestational choriocarcinoma metastasized to the kidney and lung, which presented initially as refractory hematuria after a term pregnancy 5 years earlier.

Case Report: A 35-year-old woman, G2P1, with a previous history of full-term pregnancy in 2009, presented to the emergency department complaining of intermittent gross hematuria for 2 months. Abdominal computed tomography showed a suspicious arteriovenous malformation in the right kidney and a thrombus within the right renal vein. Read More

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http://dx.doi.org/10.1016/j.tjog.2015.08.028DOI Listing
December 2016
9 Reads

Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Dual Wire-Maintaining Technique.

Heart Lung Circ 2017 Jul 7;26(7):690-695. Epub 2016 Dec 7.

Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, PR China. Electronic address:

Objective: The present study was designed to evaluate the safety and feasibility of transcatheter closure of perimembranous ventricular septal defects (PmVSDs) with dual wire-maintaining technique (DWMT).

Patients/methods: From January 2010 to December 2013, a total of 241 patients (men: 109, women: 132; mean age: 22.2±15. Read More

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http://dx.doi.org/10.1016/j.hlc.2015.06.834DOI Listing
July 2017
12 Reads

Defective adgra2 (gpr124) splicing and function in zebrafish ouchless mutants.

Development 2017 01 15;144(1):8-11. Epub 2016 Dec 15.

Laboratory of Neurovascular Signaling, Department of Molecular Biology, ULB Neuroscience Institute, Université libre de Bruxelles (ULB), B-6041 Gosselies, Belgium

A hitherto unidentified N-ethyl-N-nitrosourea (ENU)-induced mutation affects dorsal root ganglia (DRG) formation in ouchless mutant zebrafish larvae. In contrast to previous findings assigning the ouchless phenotypes to downregulated sorbs3 transcript levels, this work re-attributes the phenotypes to an essential splice site mutation affecting adgra2 (gpr124) splicing and function. Accordingly, ouchless mutants fail to complement previously characterized adgra2 mutants and exhibit highly penetrant cerebrovascular defects. Read More

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http://dx.doi.org/10.1242/dev.146803DOI Listing
January 2017
3 Reads

A 32-Year-Old-Man With a Severe Headache, Visual Loss, and Nodular Pulmonary Opacities.

Chest 2016 Nov;150(5):e137-e141

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Electronic address:

A 32-year-old man presented with severe headache, vomiting, and painless loss of vision of 5 days' duration. He had no seizures, other neurologic deficits, or fever. Two months prior to presentation, he had an episode of hemoptysis of 30 to 50 mL, which resolved spontaneously; there was no recurrence. Read More

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http://dx.doi.org/10.1016/j.chest.2016.05.011DOI Listing
November 2016
9 Reads

Delayed High Output Heart Failure due to Arteriovenous Fistula Complicated with Herniated Disc Surgery.

J Korean Med Sci 2016 Dec;31(12):2051-2053

Department of Internal Medicine, Weiss Memorial Hospital, Chicago, IL, USA.

A 36-year-old male presented with progressive exertional dyspnea over months. Physical examination showed jugular venous distension, lung crecipitations, femoral bruit and pitting pedal edema. Echocardiogram showed a dilated right ventricle with severe pulmonary hypertension and a non collapsing inferior vena cava (IVC). Read More

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http://synapse.koreamed.org/DOIx.php?id=10.3346/jkms.2016.31
Publisher Site
http://dx.doi.org/10.3346/jkms.2016.31.12.2051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102873PMC
December 2016
3 Reads

[Anomalous Systemic Arterialization of a Normal Basal Lung Segment with Aneurysm of the Aberrant Artery].

Kyobu Geka 2016 Nov;69(12):1003-1007

Department of Surgery, Oita Prefectural Hospital, Oita, Japan.

A 40-year-old woman was noted to have clubbing of the nails during an outpatient service for smoking cessation. Chest computed tomography showed an aneurysm of an aberrant artery running from the descending aorta to the left lower lobe. Hence, we diagnosed anomalous systemic arterialization of the lung. Read More

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November 2016
26 Reads

Pulmonary venous varix: A rare entity imitating arteriovenous malformation.

Arch Bronconeumol 2016 Nov 27;52(11):562-563. Epub 2015 Oct 27.

Servicio de Radiodiagnóstico (CDIC), Hospital Clínic, Barcelona, España.

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http://dx.doi.org/10.1016/j.arbres.2015.08.005DOI Listing
November 2016
2 Reads

Large left lung mass: an unexpected finding.

EuroIntervention 2016 Oct;12(9):1194

Department of Coronary Artery and Structural Heart Diseases, Institute of Cardiology, Warsaw, Poland.

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http://dx.doi.org/10.4244/EIJV12I9A193DOI Listing
October 2016
4 Reads
3.770 Impact Factor

Hereditary hemorrhagic telangiectasia with bilateral pulmonary vascular malformations: A case report.

Authors:

Vojnosanit Pregl 2016 Oct;73(10):956-60

Introduction: Hereditary hemorrhagic telangiectasia (HHT) also known as Osler-Weber-Rendu syndrome is an autosomal dominant disease that occurs due to vascular dysplasia associated with the disorder in the signaling pathway of transforming growth factor β (TGF-β). The clinical consequence is a disorder of blood vessels in multiple organ systems with the existence of telangiectasia which causes dilation of capillaries and veins, are present from birth and are localized on the skin and mucosa of the mouth, respiratory, gastrointestinal and urinary tract. They can make a rupture with consequent serious bleeding that can end up with fatal outcome. Read More

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http://dx.doi.org/10.2298/VSP150515094LDOI Listing
October 2016
3 Reads

Anomalous Feeding of the Left Upper Lobe.

Ann Thorac Surg 2016 Sep;102(3):e193-e194

Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

We report the case of a 53-year-old woman who presented with massive hemoptysis. Computed tomographic angiography revealed an anomalous vessel arising from the abdominal aorta, coursing anteriorly and through the diaphragm, and feeding the left upper lobe. At operation the vessel was found to anastomose to the left upper lobe lingula, which contained multiple vascular abnormalities and arteriovenous fistulas. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2016.01.050DOI Listing
September 2016
6 Reads

Multi-organ benign and malignant tumors: recognizing Cowden syndrome: a case report and review of the literature.

BMC Res Notes 2016 Aug 4;9:388. Epub 2016 Aug 4.

Radiology, University of the West Indies, St. Augustine, Trinidad & Tobago.

Background: Cowden syndrome is an autosomal dominant disorder with a predisposition to multiple benign and malignant tumors. In our patient, in addition to breast and endometrial malignancies as well as facial trichilemmomas, she was noted to have multiple meningiomas, pancreatic lipomas and lung cysts. These latter lesions have been noted in previous Cowden syndrome case reports, but are not included in the diagnostic criteria at this time. Read More

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http://dx.doi.org/10.1186/s13104-016-2195-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973052PMC
August 2016
19 Reads

Hepatopulmonary Shunting: A Prognostic Indicator of Survival in Patients with Metastatic Colorectal Adenocarcinoma Treated with Y Radioembolization.

Radiology 2017 Jan 19;282(1):281-288. Epub 2016 Jul 19.

From the Dept of Radiology, Univ of California San Diego School of Medicine, 200 W. Arbor Dr 8756, San Diego, CA 92103-8756 (K.H.N., M.S., N.A., C.K.H., J.M., S.C.R.); Data Reduction, Chester, NJ (M.V.B.); Sarah Cannon Research Inst, Nashville, Tenn (A.S.K.); Sirtex Medical, West Grove, Pa (K.T.); Fox Chase Cancer Ctr, Philadelphia, Pa (D.S.B., S.J.C., S.G.P.); Radiologic Associates of Hollywood, Pembroke Pines, Fla (M.C.); James Graham Brown Cancer Ctr, Univ of Louisville, Louisville, Ky (D.M.C.); Fairfax Radiological Consultants, Fairfax, Va (A.D.); Abbott Northwestern Hosp, Minneapolis, Minn (E.E.); Inova Fairfax Hosp, Annandale, Va (S.K.); Radiology Imaging Associates, Englewood, Colo (C.W.N.); Dept of Radiology, Univ of Maryland Medical School, Baltimore, Md (F.M.M., N.K.S.); Beaumont Hosp, Royal Oak, Mich (M.A.S., E.A.W.); and Cancer Ctrs of North Carolina, Cary, NC (S.S.).

Purpose To determine if high lung shunt fraction (LSF) is an independent prognostic indicator of poor survival in patients who undergo yttrium 90 radioembolization for unresectable liver-dominant metastatic colorectal cancer. Materials and Methods Retrospective data were analyzed from 606 patients (62% men; mean age, 62 years) who underwent radioembolization to treat liver metastases from colorectal adenocarcinoma between July 2002 and December 2011 at 11 U.S. Read More

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http://dx.doi.org/10.1148/radiol.2016152100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207118PMC
January 2017
70 Reads

[Lung Segmentectomy Using Video-assisted Thoracic Surgery for Lung Cancer in a Patient with Situs Inversus Totalis].

Kyobu Geka 2016 Jul;69(7):521-4

Department of Thoracic Surgery, Nishigunma National Hospital, Shibukawa, Japan.

The case was 83-year-old man who had complete situs inversus, and was pointed out to have peripheral adenocarcinoma with the size of 1.8 cm at the left upper lobe( S3). Because of severe emphysema and other multiple comorbidities, left S3 segmentectomy with hilar lymph node sampling was performed using video-assisted thoracic surgery (VATS). Read More

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July 2016
7 Reads

An uncommon cause of multiple pulmonary nodules; hereditary hemorrhagic telangiectasia.

Tuberk Toraks 2016 Mar;64(1):73-6

Department of Radiology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.

Hereditary hemorrhagic telangiectasia (HHT), or Rendu-Osler-Weber syndrome (ROWS) is a very rare hereditary disease. The diagnosis is based on the clinical findings such as recurrent epistaxis, telangiectases, visceral arteriovenous malformations (AVMs) and family history. AVMs are found in the liver, lung or brain and could mimick the masses of these organs. Read More

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March 2016
4 Reads

An extremely rare case report of surgery of lung cancer with the absence of azygos vein.

Surg Radiol Anat 2017 Jan 4;39(1):103-106. Epub 2016 Jun 4.

Department of Thoracic Surgery, Saitama Cancer Center, 780 Komuro, Ina, Kita-adachi-gun, Saitama, 362-0806, Japan.

In thoracic surgery, we occasionally encounter vessel anomalies. We herein report an extremely rare surgical case with the absence of the azygos vein. Mediastinal vascular abnormalities are said to be rare. Read More

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http://dx.doi.org/10.1007/s00276-016-1704-zDOI Listing
January 2017
5 Reads

Transarterial Embolization of Anomalous Systemic Arterial Supply to Normal Basal Segments of the Lung.

Cardiovasc Intervent Radiol 2016 Sep 5;39(9):1256-65. Epub 2016 May 5.

Department of Radiology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, 507 Zhengmin Road, Shanghai, 200433, China.

Purpose: To evaluate transarterial embolization (TAE) for the management of anomalous systemic arterial (ASA) supply to normal basal segments of the lung.

Methods: Thirteen patients with ASA supply to normal basal segments of the lung underwent TAE. All patients presented with hemoptysis and had complete-type anomalies on pre-TAE or post-TAE computed tomography (CT). Read More

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http://dx.doi.org/10.1007/s00270-016-1361-yDOI Listing
September 2016
3 Reads

Arteriovenous fistula between descending aorta and left inferior pulmonary vein: Closure with vascular plugs.

Turk Kardiyol Dern Ars 2016 Mar;44(2):151-3

Department of Pediatrics, Sakarya University Faculty of Medicine, Sakarya, Turkey.

Echocardiography revealed systemic artery to pulmonary venous fistula, a rare vascular anomaly, in a 20-month-old girl, and multislice computed tomography angiography (CTA) was performed to rule out congenital heart disease. Normal bronchial connection and pulmonary vasculature were observed in the lung. The fistula drained through the left inferior pulmonary vein to the left atrium leading to a left-to-left shunt. Read More

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http://archivestsc.com/jvi.aspx?un=TKDA-28235
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http://dx.doi.org/10.5543/tkda.2015.28235DOI Listing
March 2016
6 Reads

Follow-up of pulmonary right-to-left shunt in hereditary haemorrhagic telangiectasia.

Eur Respir J 2016 06 10;47(6):1750-7. Epub 2016 Mar 10.

Dept of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.

Pulmonary arteriovenous malformations (PAVMs) are associated with severe neurological complications in hereditary haemorrhagic telangiectasia (HHT). Transthoracic contrast echocardiography (TTCE) is recommended for screening of pulmonary right-to-left shunts (RLS). Although growth of PAVMs is shown in two small studies, no studies on follow-up with TTCE exist. Read More

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http://dx.doi.org/10.1183/13993003.01588-2015DOI Listing
June 2016
8 Reads

Coil embolization for a vast and complex arteriovenous malformation in the posterior mediastinum.

Int J Clin Exp Med 2015 15;8(9):16838-41. Epub 2015 Sep 15.

Department of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan Province, P. R. China.

Arteriovenous malformation (AVM) is a kind of life threatened disease. Especially AVM in the posterior mediastinum is a rare, painful and it is difficult for treatment. We report a 44-year-old male patient who developed arteriovenous malformation (AVM) in the posterior mediastinum. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659118PMC
December 2015
40 Reads

Multimodality Imaging Diagnostic Approach of Systemic-to-Pulmonary Vein Fistulae.

Echocardiography 2016 Mar 24;33(3):484-7. Epub 2015 Nov 24.

Department of Radiology, University Hospital of Strasbourg, Strasbourg, France.

A 26-year-old man with a history of bilateral lung transplantation for pulmonary cystic fibrosis 6 months before was admitted in our institution for acute heart failure. Cardiac magnetic resonance imaging (CMR) showed an increased aortic output, as aortic flow assessed by velocity mapping was twofold the pulmonary flow, an occluded superior vena cava (SVC), and enlarged azygos vein. A systemic-to-pulmonary vein fistula (SAPVF) was suspected. Read More

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http://dx.doi.org/10.1111/echo.13116DOI Listing
March 2016
17 Reads

Case Report: Brown Fat Accumulation of Tc-99m Macroaggregated Albumin in a Lung Perfusion Study in a Patient With Multiple Lung Arteriovenous Malformations and Right-to-Left Shunting.

Medicine (Baltimore) 2015 Oct;94(42):e1820

From the Department of Radiology and Radiological Science, Division of Nuclear Medicine, Russell H. Morgan, Johns-Hopkins University School ofMedicine, Baltimore, MD (WM); Mallinckrodt Institute of Radiology, Washington University in St. Louis School Of Medicine, St. Louis, MO (RLW).

An 18-year-old man was preoperatively assessed for a varicocele and found to be hypoxemic. A Tc-99m macroaggregated albumin lung perfusion scan showed right-to-left shunting, evidenced by increased radiotracer uptake in the brain, kidneys, thyroid gland, and bilateral supraclavicular areas, a typical location for brown adipose tissue. Chest computerized tomography angiogram study showed supraclavicular fat density areas and multiple pulmonary arteriovenous malformations. Read More

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https://insights.ovid.com/crossref?an=00005792-201510030-000
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http://dx.doi.org/10.1097/MD.0000000000001820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620802PMC
October 2015
2 Reads

Imaging features and transcatheter treatment of a giant pulmonary arteriovenous malformation in an elderly patient.

BJR Case Rep 2016 8;2(1):20150005. Epub 2015 Oct 8.

Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Yishun Central, Singapore.

Pulmonary arteriovenous malformations (PAVMs) comprise an anomalous communication between the pulmonary arterial and systemic circulation. The drainage is usually into one of the pulmonary veins, although rare instances of direct drainage into the left atrium or inferior vena cava have been reported. The result is a high-flow, low-resistance, right-toleft shunt. Read More

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http://dx.doi.org/10.1259/bjrcr.20150005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195913PMC
October 2015

A 58-year-old woman with hypoxia, hypoxaemia, a hole in the heart and a … herring! Intracardiac or extracardiac shunt? That is the question!

BMJ Case Rep 2015 Sep 25;2015. Epub 2015 Sep 25.

Department of Cardiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

We describe a case of a previously healthy 58-year-old woman who presented with gradual onset shortness of breath on exertion, erythrocytosis, hypoxia and hypoxaemia. Initial investigations revealed a normal chest radiography and pulmonary function test, however, there was an isolated reduction in diffusion capacity. She was subsequently found to have a patent foramen ovale (PFO) with intermittent shunting. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2015-21197
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http://dx.doi.org/10.1136/bcr-2015-211975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600829PMC
September 2015
7 Reads