2,258 results match your criteria Imaging in Acute Respiratory Distress Syndrome


Usefulness of ultrasound in the management of acute respiratory distress syndrome.

Int J Crit Illn Inj Sci 2019 Jan-Mar;9(1):11-15

Department of Critical Care, King Hamad University Hospital, Al Muharaq, Kingdom of Bahrain.

Acute respiratory distress syndrome (ARDS) is a life-threatening disease. Different imaging techniques have been used to diagnose and guide the ventilatory management of patients with ARDS. Chest ultrasound is a reliable tool to identify interstitial syndrome, lung consolidation, lung collapse, and pleural effusion. Read More

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http://www.ijciis.org/text.asp?2019/9/1/11/253758
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http://dx.doi.org/10.4103/IJCIIS.IJCIIS_30_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423925PMC
April 2019
1 Read

[Effects of Hippo signaling pathway on lung injury repair by mesenchymal stem cells in acute respiratory distress syndrome].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2019 Mar;31(3):281-287

Department of Critical Care Medicine, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, Jiangsu, China. Corresponding author: Dong Liang, Email:

Objective: To investigate the effects of Hippo signaling pathway on lung injury repair of mesenchymal stem cells (MSC) in acute respiratory distress syndrome (ARDS) and its mechanism.

Methods: Mouse bone marrow-derived MSC (mMSCs) cell lines with low expression of large tumor suppressor 2 (LATS2) were constructed by lentiviral vector transfection. Male C57BL/6 mice aging 6-8 weeks old were divided into four groups according to random number table (n = 36). Read More

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http://dx.doi.org/10.3760/cma.j.issn.2095-4352.2019.03.005DOI Listing
March 2019
1 Read

Acute Respiratory Distress Syndrome Associated With Clopidogrel in a Young Male Patient.

Front Med (Lausanne) 2019 8;6:38. Epub 2019 Mar 8.

Department of Neurology, Duke University, Durham, NC, United States.

Clopidogrel is a commonly prescribed antiplatelet drug in patients with stents and histories of arterial vascular disease. It generally has a favorable side effect profile with increasing bleeding risk as the main concern as an adverse event. A 19-year-old previously healthy male presented to the neurological intensive care unit with a subarachnoid hemorrhage requiring a flow diverting stent to secure the aneurysm. Read More

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http://dx.doi.org/10.3389/fmed.2019.00038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419477PMC
March 2019
2 Reads

Dynamic changes of pulmonary arterial pressure in perinatal neonates with pulmonary and extrapulmonary acute lung injury/respiratory distress syndrome.

Medicine (Baltimore) 2019 Mar;98(11):e14830

Department of Neonate, Yancheng Third People's Hospital, Yancheng, China.

This study aims to explore the dynamic changes of pulmonary arterial pressure (PAP) and its clinical significance in prenatal neonates with pulmonary and extra-pulmonary acute lung injury/respiratory distress syndrome (ALI/ARDS).A prospective study was conducted in the Neonate Intensive Care Unit (NICU) between May 2015 and April 2017. A total of 78 prenatal neonates with ALI/ARDS were selected and divided into 2 groups: pulmonary group (n = 37) and extra-pulmonary group (n = 41). Read More

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http://dx.doi.org/10.1097/MD.0000000000014830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426575PMC
March 2019
4 Reads

Quality of Life and Lung Function in Survivors of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome.

Anesthesiology 2019 Apr;130(4):572-580

From the Department of Anesthesia, Critical Care, and Emergency, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda - Ospedale Maggiore Policlinico, Milan (MI), Italy (G.G., V.S., D.T., R.R., A.P.) Department of Pathophysiology and Transplantation, University of Milan, Milan (MI), Italy (G.G., F.C., F.B., L.C.M., E.S., A.P.) Department of Preventive Medicine, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda - Ospedale Maggiore Policlinico, Milan (MI), Italy (L.P.) Department of Anesthesiology, Emergency and Intensive Care Medicine, University of Göttingen, Göttingen, Germany (L.G.) Department of Health Sciences, University of Milan, Milan (MI), Italy (D.C.).

What We Already Know About This Topic: Extracorporeal membrane oxygenation is used in severe acute respiratory distress syndrome; whereas the long-term complications among survivors of acute respiratory distress syndrome treated without extracorporeal membrane oxygenation are well described, the status of extracorporeal membrane oxygenation survivors is poorly understood WHAT THIS ARTICLE TELLS US THAT IS NEW: In a single-center cohort of acute respiratory distress syndrome survivors, management with (vs. without) extracorporeal membrane oxygenation resulted in similar survival at 1 yr, pulmonary function, and computed tomography lung imaging, but less impairment in quality of life BACKGROUND:: Survivors of acute respiratory distress syndrome (ARDS) have long-term impairment of pulmonary function and health-related quality of life, but little is known of outcomes of ARDS survivors treated with extracorporeal membrane oxygenation. The aim of this study was to compare long-term outcomes of ARDS patients treated with or without extracorporeal membrane oxygenation. Read More

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http://Insights.ovid.com/crossref?an=00000542-201904000-0001
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http://dx.doi.org/10.1097/ALN.0000000000002624DOI Listing
April 2019
12 Reads

[Clinical characteristics of human adenovirus type 7 pneumonia and genetic characteristics of human adenovirus type 7].

Zhonghua Jie He He Hu Xi Za Zhi 2019 Mar;42(3):206-212

Department of Respiration, Army General Hospital 263, Beijing 101149, China.

To better understand the clinical features of human adenovirus type 7 (hAdV7) pneumonia and to identify whether there is a variation in the genome of the strain (CHN/BeiJing/2018) isolated during the small-scale epidemic. Forty-two patients were diagnosed with hAdV7 pneumonia between October 27th, 2017 and February 28th, 2018. They were all males with an average age of (21±2) years. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1001-0939.2019.03.011DOI Listing
March 2019
2 Reads

Explore potential plasma biomarkers of acute respiratory distress syndrome (ARDS) using GC-MS metabolomics analysis.

Clin Biochem 2019 Apr 16;66:49-56. Epub 2019 Feb 16.

Departmen of Emergency and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, China. Electronic address:

Objectives: The aim of this study was to analyse the metabolomics of patients with acute respiratory distress syndrome (ARDS) for the identification of metabolic markers with potential diagnostic and prognostic value.

Methods: The enrolled subjects included adult patients with ARDS that met the Berlin definition and healthy controls matched based on age, gender, and body mass index (BMI). Plasma samples were collected from 37 patients with ARDS and 28 healthy controls. Read More

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http://dx.doi.org/10.1016/j.clinbiochem.2019.02.009DOI Listing
April 2019
1 Read

Mechanosensitive Rap1 activation promotes barrier function of lung vascular endothelium under cyclic stretch.

Mol Biol Cell 2019 Apr 13;30(8):959-974. Epub 2019 Feb 13.

Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201.

Mechanical ventilation remains an imperative treatment for the patients with acute respiratory distress syndrome, but can also exacerbate lung injury. We have previously described a key role of RhoA GTPase in high cyclic stretch (CS)-induced endothelial cell (EC) barrier dysfunction. However, cellular mechanotransduction complexes remain to be characterized. Read More

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https://www.molbiolcell.org/doi/10.1091/mbc.E18-07-0422
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http://dx.doi.org/10.1091/mbc.E18-07-0422DOI Listing
April 2019
8 Reads

Platelets inhibit apoptotic lung epithelial cell death and protect mice against infection-induced lung injury.

Blood Adv 2019 Feb;3(3):432-445

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.

Thrombocytopenia is associated with worse outcomes in patients with acute respiratory distress syndrome, which is most commonly caused by infection and marked by alveolar-capillary barrier disruption. However, the mechanisms by which platelets protect the lung alveolar-capillary barrier during infectious injury remain unclear. We found that natively thrombocytopenic mice deficient in the thrombopoietin receptor sustain severe lung injury marked by alveolar barrier disruption and hemorrhagic pneumonia with early mortality following acute intrapulmonary (PA) infection; barrier disruption was attenuated by platelet reconstitution. Read More

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http://dx.doi.org/10.1182/bloodadvances.2018026286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373758PMC
February 2019
2 Reads

Disseminated Blastomycosis in a Teenager Presenting with Pleural Effusion and Splenomegaly.

J Emerg Med 2019 Mar 25;56(3):e23-e26. Epub 2019 Jan 25.

Medical College of Wisconsin, Milwaukee, Wisconsin; Children's Hospital of Wisconsin, Milwaukee, Wisconsin.

Background: Blastomycosis is caused by a fungus endemic to states and providences bordering the Lawrence Rivers and the Great Lakes. It can lead to significant pathology in both immunocompetent and immunocompromised hosts. This case report describes disseminated blastomycosis in an otherwise healthy 16-year-old patient. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.12.035DOI Listing
March 2019
2 Reads

Imaging the Injured Lung: Mechanisms of Action and Clinical Use.

Anesthesiology 2019 Jan 17. Epub 2019 Jan 17.

From the Department of Anesthesiology and Critical Care and the Department of Radiology (M.C., Y.X., R.R.R.) University of Pennsylvania, Philadelphia, Pennsylvania; the Interdepartmental Division of Critical Care Medicine and Department of Medicine (A.G.) Hospital for Sick Children (B.P.K., T.Y.), University of Toronto, Toronto, Ontario, Canada the Departments of Anesthesia and Biomedical Engineering (J.H.) and Anesthesia, Radiology, and Biomedical Engineering (D.W.K.), University of Iowa, Iowa City, Iowa the Hedenstierna Laboratory and Uppsala University Hospital, Uppsala University, Uppsala, Sweden (G.P.).

Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure characterized by massive and heterogeneously distributed loss of lung aeration caused by diffuse inflammation and edema present in interstitial and alveolar spaces. It is defined by consensus criteria, which include diffuse infiltrates on chest imaging-either plain radiography or computed tomography. This review will summarize how imaging sciences can inform modern respiratory management of ARDS and continue to increase the understanding of the acutely injured lung. Read More

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http://dx.doi.org/10.1097/ALN.0000000000002583DOI Listing
January 2019
49 Reads
5.879 Impact Factor

IMPACT probability of poor outcome and plasma cytokine concentrations are associated with multiple organ dysfunction syndrome following traumatic brain injury.

J Neurosurg 2019 Jan 11:1-7. Epub 2019 Jan 11.

Departments of1Neurosurgery and.

OBJECTIVETraumatic brain injury (TBI) is a major cause of morbidity and mortality. Multiple organ dysfunction syndrome (MODS) occurs frequently after TBI and independently worsens outcome. The present study aimed to identify potential admission characteristics associated with post-TBI MODS. Read More

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http://dx.doi.org/10.3171/2018.8.JNS18676DOI Listing
January 2019
9 Reads

Dead space ventilation promotes alveolar hypocapnia reducing surfactant secretion by altering mitochondrial function.

Thorax 2019 Mar 12;74(3):219-228. Epub 2019 Jan 12.

Department of Anesthesiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

Background: In acute respiratory distress syndrome (ARDS), pulmonary perfusion failure increases physiologic dead space ventilation (V/V), leading to a decline of the alveolar CO concentration [CO]. Although it has been shown that alveolar hypocapnia contributes to formation of atelectasis and surfactant depletion, a typical complication in ARDS, the underlying mechanism has not been elucidated so far.

Methods: In isolated perfused rat lungs, cytosolic or mitochondrial Ca concentrations ([Ca] or [Ca], respectively) of alveolar epithelial cells (AECs), surfactant secretion and the projected area of alveoli were quantified by real-time fluorescence or bright-field imaging (n=3-7 per group). Read More

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http://dx.doi.org/10.1136/thoraxjnl-2018-211864DOI Listing
March 2019
5 Reads

The Right Ventricle During Selective Lung Ventilation for Thoracic Surgery.

J Cardiothorac Vasc Anesth 2018 Nov 22. Epub 2018 Nov 22.

University Hospitals Birmingham National Health Service Foundation Trust, Department of Critical Care Medicine, Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK; Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, Centre of Translational Inflammation Research, University of Birmingham, Birmingham, UK.

The right ventricle (RV) has been an area of evolving interest after decades of being ignored and considered less important than the left ventricle. Right ventricular dysfunction/failure is an independent predictor of mortality and morbidity in cardiac surgery; however, very little is known about the incidence or impact of RV dysfunction/failure in thoracic surgery. The pathophysiology of RV dysfunction/failure has been studied in the context of acute respiratory distress syndrome (ARDS), cardiac surgery, pulmonary hypertension, and left ventricular failure, but limited data exist in literature addressing the issue of RV dysfunction/failure in the context of thoracic surgery and one-lung ventilation (OLV). Read More

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http://dx.doi.org/10.1053/j.jvca.2018.11.030DOI Listing
November 2018
4 Reads

Endovascular Trapping of Large Cervical Carotid Pseudoaneurysm in Marfan Syndrome Presenting with Progressive Respiratory Distress.

World Neurosurg 2019 Mar 24;123:323-327. Epub 2018 Dec 24.

Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, The National Neuroscience Institute, King Fahad Medical City, Riyadh, Saudi Arabia.

Background: Isolated cervical pseudoaneurysms of the internal carotid artery (ICA) in patients with Marfan syndrome are extremely rare.

Case Description: A 73-year-old female with Marfan syndrome and history of multiple aortic aneurysms presented to an outside hospital with dysphagia, a mass in her neck, dizziness, nausea, and vomiting. A computed tomography angiogram showed bilateral cervical ICA pseudoaneurysms, more significant on the right side. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183287
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http://dx.doi.org/10.1016/j.wneu.2018.12.050DOI Listing
March 2019
18 Reads
2.417 Impact Factor

Rapid emergence of cryptococcal fungemia, Mycobacterium chelonae vertebral osteomyelitis and gastro intestinal stromal tumor in a young HIV late presenter: a case report.

BMC Infect Dis 2018 Dec 27;18(1):693. Epub 2018 Dec 27.

Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.

Background: Highly active antiretroviral therapy has significantly changed the natural history of HIV infection, leading to a dramatic reduction of HIV-related morbidity and mortality. Late Presenters, Very Late Presenters and AIDS presenters still represent, also in Europe, including Italy, a huge challenge in terms of diagnostic and therapeutic management.

Case Presentation: A 35-year-old male with a history of fever and back pain. Read More

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http://dx.doi.org/10.1186/s12879-018-3573-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307234PMC
December 2018
5 Reads

IL-35 interferes with splenic T cells in a clinical and experimental model of acute respiratory distress syndrome.

Int Immunopharmacol 2019 Feb 22;67:386-395. Epub 2018 Dec 22.

The Laboratory of Lipid & Glucose Metabolism, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Emergency and Critical Care Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address:

Acute respiratory distress syndrome (ARDS) is a life-threatening critical care syndrome with uncontrolled inflammation that is a central issue. Its main characteristic is inflammatory mediators and cytokines as well as agglutinating chemokines that injure target cells. Interleukin (IL)-35 is a newly identified IL-12 cytokine family member with structural similarities to other IL-12, IL-23, and IL-27 cytokines but unique immunological functions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15675769183133
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http://dx.doi.org/10.1016/j.intimp.2018.12.024DOI Listing
February 2019
11 Reads

Lung Ultrasound as a New Technique for Diagnosis of Neonatal Respiratory Diseases.

Authors:
Yasser N Elsayed

Neonatal Netw 2018 Jul 1;37(4):224-232. Epub 2018 Jul 1.

Point-of-care ultrasound in the NICU is becoming more commonplace and is now used for a number of indications. Over the past ten years, the use of ultrasound as an alternative to a chest x-ray for the diagnosis of neonatal lung disease has been explored, and protocols were developed to refine the interpretation of ultrasound images in neonatal lung disease. The purpose of this column is to briefly explain the physics of ultrasound and describe the application of ultrasound to neonatal lung assessment. Read More

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http://dx.doi.org/10.1891/0730-0832.37.4.224DOI Listing

Severe aortic regurgitation masked as sepsis-induced ARDS in a patient with endocarditis.

BMJ Case Rep 2018 Dec 4;11(1). Epub 2018 Dec 4.

Internal Medicine, Aventura Hospital and Medical Center, Aventura, Florida, USA.

Septic shock is the most common type of shock in the intensive care unit with an associated mortality close to 50%. Infective endocarditis (IE) is a rare cause of septic shock but carries significant morbidity and mortality. Group B IE (GBS-IE) is an invasive infection with an incidence of approximately 1. Read More

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http://www.bmj.com/lookup/doi/10.1136/bcr-2018-226681
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http://dx.doi.org/10.1136/bcr-2018-226681DOI Listing
December 2018
17 Reads

Undiagnosed hypertrophic obstructive cardiomyopathy during transcatheter aortic valve replacement: a case report.

J Med Case Rep 2018 Dec 18;12(1):372. Epub 2018 Dec 18.

Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida, USA.

Background: Transcatheter aortic valve replacement is indicated for severe symptomatic aortic stenosis in patients who have a very high or prohibitive surgical risk as assessed pre-procedurally by the Society of Thoracic Surgery Risk Score, EuroSCORE (II), frailty testing, and other predictors. When combined with another left ventricular outflow tract obstruction, careful consideration must be taken prior to proceeding with transcatheter aortic valve replacement because an additional masked left ventricular outflow tract pathology can lead to challenging hemodynamics in the peri-deployment phase, as reported in this case.

Case Presentation: A 56-year-old Caucasian man with multiple comorbidities and severe aortic stenosis underwent transcatheter aortic valve replacement under monitored anesthesia care. Read More

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http://dx.doi.org/10.1186/s13256-018-1904-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298014PMC
December 2018
9 Reads

Rare respiratory diseases in the ICU: when to suspect them and specific approaches.

Curr Opin Crit Care 2019 Feb;25(1):29-36

Université Paris Est Créteil, Faculté de Médecine de Créteil, Groupe de Recherche Clinique CARMAS, Créteil.

Purpose Of Review: A prompt identification of the cause of acute respiratory failure (ARF)/acute respiratory distress syndrome (ARDS) is required in order to initiate a targeted treatment. Yet, almost 10% of ARDS patients have no identified ARDS risk factor at ARDS diagnosis. Numerous rare causes of ARF have been reported in this setting. Read More

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http://dx.doi.org/10.1097/MCC.0000000000000572DOI Listing
February 2019
15 Reads

Pulmonary veno-occlusive disease as a cause of severe pulmonary hypertension in a dog.

Acta Vet Scand 2018 Dec 5;60(1):78. Epub 2018 Dec 5.

Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3508 TD, Utrecht, The Netherlands.

Background: Pulmonary veno-occlusive disease (PVOD) is a rare cause of pulmonary arterial hypertension (PAH) in humans and can be classified in idiopathic, heritable, drug and radiation-induced, and associated with connective tissue disease or human immunodeficiency virus infection. Recently, biallelic mutations of the EIF2AK4 gene have been discovered as a cause for an autosomal recessive form of PVOD in humans. In dogs, PAH is poorly characterized and is generally considered to be idiopathic or secondary to (for example) congenital left-to right cardiovascular shunts or heartworm disease. Read More

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https://actavetscand.biomedcentral.com/articles/10.1186/s130
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http://dx.doi.org/10.1186/s13028-018-0433-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282261PMC
December 2018
19 Reads

Intravascular large B-cell lymphoma presenting with diffusely increased pulmonary fluorodeoxyglucose uptake without corresponding CT abnormality.

Radiol Case Rep 2019 Feb 23;14(2):260-264. Epub 2018 Nov 23.

Department of Radiology, Kansas University Hospital, 3901 Rainbow Blvd, MS 4032, Kansas City, KS, USA.

A 60-year-old male presented with complaints of dyspnea, intermittent fever, and 40 pounds of weight loss over the previous 9 months and was admitted for acute hypoxemic respiratory failure. Labs demonstrated elevated inflammatory markers, mild anemia, and thrombocytopenia. Fluorodeoxyglucose-positron emission tomography scan demonstrated diffusely increased pulmonary fluorodeoxyglucose uptake without corresponding abnormality on CT images. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19300433183045
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http://dx.doi.org/10.1016/j.radcr.2018.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260434PMC
February 2019
10 Reads

Acute respiratory distress syndrome after the use of gadolinium contrast agent.

Respir Med Case Rep 2018 24;25:336-338. Epub 2018 Oct 24.

Department of Pulmonary Diseases, Ataturk University, School of Medicine, 25240, Erzurum, Turkey.

Acute respiratory distress syndrome (ARDS) is a life-threatening medical emergency. The etiology of ARDS can involve various causes. ARDS associated with the use of iodinated contrast media is rarely reported, and the literature includes only one case of ARDS due to gadobutrol. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22130071183008
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http://dx.doi.org/10.1016/j.rmcr.2018.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223103PMC
October 2018
17 Reads

Post esophagectomy diaphragmatic hernia: a case report of a rare cause of acute respiratory distress.

J Cardiothorac Surg 2018 Nov 15;13(1):114. Epub 2018 Nov 15.

Service of Cardiac Surgery, Multidisciplinary Department of Cardiology, Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, QC, Canada.

Background: Diaphragmatic hernia is frequent among the elderly and is usually associated with mild chronic digestive and respiratory symptoms.

Case Presentation: An elderly post-esophagectomy male patient, in the early postoperative period of cardiac surgery, presented with acute respiratory distress. An emergent surgery was performed to reduce a giant diaphragmatic herniation. Read More

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http://dx.doi.org/10.1186/s13019-018-0802-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238405PMC
November 2018
3 Reads

Weaning from Mechanical Ventilation in ARDS: Aspects to Think about for Better Understanding, Evaluation, and Management.

Biomed Res Int 2018 9;2018:5423639. Epub 2018 Oct 9.

Hospital de Clínicas de Porto Alegre, Brazil.

Acute respiratory distress syndrome (ARDS) is characterized by severe inflammatory response and hypoxemia. The use of mechanical ventilation (MV) for correction of gas exchange can cause worsening of this inflammatory response, called "ventilator-induced lung injury" (VILI). The process of withdrawing mechanical ventilation, referred to as weaning from MV, may cause worsening of lung injury by spontaneous ventilation. Read More

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https://www.hindawi.com/journals/bmri/2018/5423639/
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http://dx.doi.org/10.1155/2018/5423639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198583PMC
February 2019
21 Reads

An unusual presentation of gall bladder papillomatosis in association with metachromatic leukodystrophy.

BMJ Case Rep 2018 Nov 1;2018. Epub 2018 Nov 1.

Department of Paediatric Surgery, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.

A 5-year-old boy with metachromatic leukodystrophy, debilitated by spastic quadriparesis presented to us with massive ascites and respiratory distress. A subtotal cholecystectomy was performed on him from another centre for a gall bladder mass a year before he came to us. Imaging revealed a polypoidal frond-like mass arising from the gall bladder fossa which was supplied by a hypertrophied branch of the right hepatic artery. Read More

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http://dx.doi.org/10.1136/bcr-2017-224162DOI Listing
November 2018
3 Reads

Lung Ultrasound Is Accurate for the Diagnosis of High-Altitude Pulmonary Edema: A Prospective Study.

Can Respir J 2018 1;2018:5804942. Epub 2018 Oct 1.

Department of High Altitude Disease, Xizang Military General Hospital, Lhasa, China.

Objective: The aim of this study was to assess the diagnostic accuracy of lung ultrasonography (LUS) for high-altitude pulmonary edema (HAPE).

Background: LUS has proven to be a reliable tool for the diagnosis of pulmonary diseases, including pneumonia, acute respiratory distress syndrome (ARDS), and pneumothorax. LUS also has potential for the diagnosis of HAPE. Read More

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https://www.hindawi.com/journals/crj/2018/5804942/
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http://dx.doi.org/10.1155/2018/5804942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188731PMC
April 2019
18 Reads

Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study.

Lancet Respir Med 2019 Feb 22;7(2):115-128. Epub 2018 Oct 22.

Penn State Hershey Children's Hospital, Penn State University School of Medicine, Hershey, PA, USA.

Background: Paediatric acute respiratory distress syndrome (PARDS) is associated with high mortality in children, but until recently no paediatric-specific diagnostic criteria existed. The Pediatric Acute Lung Injury Consensus Conference (PALICC) definition was developed to overcome limitations of the Berlin definition, which was designed and validated for adults. We aimed to determine the incidence and outcomes of children who meet the PALICC definition of PARDS. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132600183034
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http://dx.doi.org/10.1016/S2213-2600(18)30344-8DOI Listing
February 2019
21 Reads

Electrical impedance tomography in acute respiratory distress syndrome.

Crit Care 2018 10 25;22(1):263. Epub 2018 Oct 25.

Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Acute respiratory distress syndrome (ARDS) is a clinical entity that acutely affects the lung parenchyma, and is characterized by diffuse alveolar damage and increased pulmonary vascular permeability. Currently, computed tomography (CT) is commonly used for classifying and prognosticating ARDS. However, performing this examination in critically ill patients is complex, due to the need to transfer these patients to the CT room. Read More

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https://ccforum.biomedcentral.com/articles/10.1186/s13054-01
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http://dx.doi.org/10.1186/s13054-018-2195-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203288PMC
October 2018
7 Reads

When appearances deceive: Echocardiographic changes due to common chest pathology.

Echocardiography 2018 11 18;35(11):1847-1859. Epub 2018 Oct 18.

Department of Anaesthesiology & Intensive Care, Aarhus University Hospital, Aarhus N, Denmark.

Most indications for performing echocardiography focus on the evaluation of properties intrinsic to the heart. However, numerous extra-cardiac conditions indirectly convey changes to the echocardiographic appearance through alterations in the governing physiology. Pulmonary embolism increases pulmonary arterial pressure if a sufficient cross-sectional area of the pulmonary vascular bed is occluded. Read More

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http://doi.wiley.com/10.1111/echo.14163
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http://dx.doi.org/10.1111/echo.14163DOI Listing
November 2018
10 Reads

Two Medullary Hemorrhage Cases Complicated by Respiratory Distress in the Early Phase.

J Stroke Cerebrovasc Dis 2019 Jan 15;28(1):229-231. Epub 2018 Oct 15.

Department of Neurology, Tokyo Saiseikai Central Hospital, Tokyo, Japan. Electronic address:

Medullary hemorrhage is quite rare among brain stem hemorrhage cases, thus the clinical course remains unclear. In the medulla oblongata, respiratory centers are located and previous reports indicate that medullary lesions have possible relationship with acute respiratory distress syndrome. This kind of respiratory failure is commonly caused by neurogenic pulmonary edema (NPE), which is defined as noncardiac noninfectious acute respiratory distress syndrome with changes in intracranial condition including cerebrovascular events. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.09.027DOI Listing
January 2019
3 Reads

Speckle tracking echocardiography and right ventricle dysfunction in acute respiratory distress syndrome a pilot study.

Echocardiography 2018 12 8;35(12):1982-1987. Epub 2018 Oct 8.

Intensive Care Unit and Regional ECMO Referral centre, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

Purpose: Speckle tracking echocardiography is a novel echocardiographic technique to assess RV myocardial function but no data are so far available in patients with acute respiratory distress syndrome (ARDS), and we aimed at assessing the feasibility of 2 dimensional (2D) speckle tracking echocardiography and the prognostic role of RV free wall speckle tracking strain in 30 consecutive patients with moderate-severe ARDS MATERIALS AND METHODS: In an observational prospective study, 30 consecutive patients with moderate-severe ARDS were enrolled. Echocardiography was performed within 12 hours from ICU admission.

Results: Mortality rate was 33% (10/30). Read More

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http://doi.wiley.com/10.1111/echo.14153
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http://dx.doi.org/10.1111/echo.14153DOI Listing
December 2018
3 Reads

Clinical implication of radiographic scores in acute Middle East respiratory syndrome coronavirus pneumonia: Report from a single tertiary-referral center of South Korea.

Eur J Radiol 2018 Oct 11;107:196-202. Epub 2018 Sep 11.

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.

The aim of this study is to determine the earliest cutoff of radiographic score as a potential prognostic indicator of fatal outcomes in patients with acute Middle East respiratory syndrome coronavirus (MERS-CoV) pneumonia. The institutional review board approved this retrospective study. Serial chest radiographies (CXRs) were obtained from viral exposure until death or discharge in 35 patients with laboratory confirmed MERS-CoV infection. Read More

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http://dx.doi.org/10.1016/j.ejrad.2018.09.008DOI Listing
October 2018
2 Reads
2.370 Impact Factor

Massive gastric dilatation leading to acute respiratory distress 1 year after a Nissen fundoplication.

BMJ Case Rep 2018 Sep 27;2018. Epub 2018 Sep 27.

Surgery, BHR Hospitals Trust, Romford, UK.

Acute massive gastric dilatation (AMGD) is a recognised complication after Nissen fundoplication. A 63-year-old man recently presented to our emergency department in acute respiratory distress, acute abdominal pain and distension, having had an elective umbilical port incisional hernia repair a day prior. In the year preceding his presentation, the patient had undergone a laparoscopic paraoesophageal hiatus hernia repair and excision of sac, posterior cruropexy, dual mesh reinforcement of repair and 360° fundoplication, as a day case. Read More

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http://dx.doi.org/10.1136/bcr-2018-225927DOI Listing
September 2018
3 Reads

Ventilator-Associated Pneumonia and Events in Pediatric Intensive Care: A Single Center Study.

Pediatr Crit Care Med 2018 Dec;19(12):1106-1113

Pediatric Intensive Care Unit, Sainte-Justine University Hospital Center, Montreal, QC, Canada.

Objectives: Ventilator-associated pneumonia is the second most common nosocomial infection in pediatric intensive care. The Centers for Disease Control and Prevention recently issued diagnosis criteria for pediatric ventilator-associated pneumonia and for ventilator-associated events in adults. The objectives of this pediatric study were to determine the prevalence of ventilator-associated pneumonia using these new Centers for Disease Control and Prevention criteria, to describe the risk factors and management of ventilator-associated pneumonia, and to assess a simpler method to detect ventilator-associated pneumonia with ventilator-associated event in critically ill children. Read More

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http://dx.doi.org/10.1097/PCC.0000000000001720DOI Listing
December 2018
4 Reads

Pulmonary Glue Embolism: An unusual complication following endoscopic sclerotherapy for gastric varices.

Sultan Qaboos Univ Med J 2018 May 9;18(2):e231-e235. Epub 2018 Sep 9.

Department of Radiology, Hull Royal Infirmary, Hull, UK.

A pulmonary glue embolism is an unusual but potentially life-threatening complication following the treatment of variceal bleeding, especially in patients with large varices requiring large volumes of sclerosant. Other contributory factors include the rate of injection and ratio of the constituent components of the sclerosant (i.e. Read More

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http://dx.doi.org/10.18295/squmj.2018.18.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132531PMC
May 2018
3 Reads

Radiologic and autopsy findings in a case of fatal immune checkpoint inhibitor-associated pneumonitis.

Cancer Treat Res Commun 2018 21;15:17-20. Epub 2018 Feb 21.

Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address:

Oncologists are increasingly managing drug-induced pneumonitis in lung cancer patients treated with PD-1/PD-L1 immune checkpoint inhibitors. To date only few studies on the topic have described both radiologic and pathologic findings in these patients. Here, we report a fatal case of immune checkpoint inhibitor-associated pneumonitis initially presenting with an organizing pneumonia, but who rapidly developed acute respiratory distress syndrome (confirmed histologically at the time of autopsy). Read More

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http://dx.doi.org/10.1016/j.ctarc.2018.02.004DOI Listing
February 2018
10 Reads

A Case of Acute Respiratory Distress Syndrome Caused by Waterproofing Spray Inhalation.

Tokai J Exp Clin Med 2018 Sep 20;43(3):106-110. Epub 2018 Sep 20.

Department of Emergency and Critical Care Medicine, Odawara Municipal Hospital, 46 Kuno, Odawara, Kanagawa 250-8558, Japan.

We report the case of a 62-year-old man who used approximately one can of waterproofing spray in an enclosed room and, then, smoked a cigarette. He developed a fever of 39°C with respiratory distress and was transported by ambulance to his usual doctor. Since his respiratory state was very severe, he was transferred to our hospital. Read More

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September 2018
28 Reads

Lung-Resident Mesenchymal Stem Cells Promote Repair of LPS-Induced Acute Lung Injury via Regulating the Balance of Regulatory T cells and Th17 cells.

Inflammation 2019 Feb;42(1):199-210

Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are associated with high morbidity and mortality. Mesenchymal stem cells (MSCs) have been shown to improve ALI, and the imbalance of regulatory T cells (Tregs) and Th17 cells is associated with mortality in ALI/ARDS patients. However, whether administration of lung-resident MSC (LRMSC) improves lung injury and regulates the balance of Tregs and Th17 cells remains unknown. Read More

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http://dx.doi.org/10.1007/s10753-018-0884-6DOI Listing
February 2019
2 Reads

Adjuvant lung resection in the management of nontuberculous mycobacterial lung infection: A retrospective matched cohort study.

Respir Med 2018 09 9;142:1-6. Epub 2018 Jul 9.

Division of Respirology, Department of Medicine, University Health Network, Toronto Western Hospital, 399 Bathurst Street, Toronto, ON, M5T 2S8, Canada; Department of Medicine, University of Toronto, 27 King's College Circle, Toronto, ON, M5S 1A1, Canada. Electronic address:

Background And Objectives: Lung resection in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) is considered when medical therapy alone fails to provide long term control. Data regarding comparative and long-term outcomes are limited. We aimed to review indications and outcomes of adjuvant lung resection for NTM-PD compared with controls. Read More

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http://dx.doi.org/10.1016/j.rmed.2018.07.003DOI Listing
September 2018
4 Reads

Chest radiography versus lung ultrasound for identification of acute respiratory distress syndrome: a retrospective observational study.

Crit Care 2018 08 18;22(1):203. Epub 2018 Aug 18.

Division of Critical Care-Respiratory Therapy, National University Hospital, Singapore, Singapore.

Background: Lung ultrasound may be a reasonable alternative to chest radiography for the identification of acute respiratory distress syndrome (ARDS), but the diagnostic performance of lung ultrasound for ARDS is uncertain. We therefore analyzed the clinical outcomes of ARDS diagnosed according to the Berlin Definition, using either chest radiography (Berlin-CXR) or lung ultrasound (Berlin-LUS) as an alternative imaging method.

Methods: This was a retrospective observational study in a 20-bed medical intensive care unit (ICU). Read More

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https://ccforum.biomedcentral.com/articles/10.1186/s13054-01
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http://dx.doi.org/10.1186/s13054-018-2105-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098581PMC
August 2018
12 Reads

Diagnostic value of cardiopulmonary ultrasound in elderly patients with acute respiratory distress syndrome.

BMC Pulm Med 2018 Aug 13;18(1):136. Epub 2018 Aug 13.

Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.

Background: Lung ultrasound and echocardiography are mainly applied in critical care and emergency medicine. However, the diagnostic value of cardiopulmonary ultrasound in elderly patients with acute respiratory distress syndrome (ARDS) is still unclear.

Methods: Consecutive patients admitted to ICU with the diagnosis of suspected ARDS based on clinical grounds were enrolled. Read More

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http://dx.doi.org/10.1186/s12890-018-0666-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090678PMC
August 2018
8 Reads

Distribution of alveolar-interstitial syndrome in dogs and cats with respiratory distress as assessed by lung ultrasound versus thoracic radiographs.

J Vet Emerg Crit Care (San Antonio) 2018 Sep 3;28(5):415-428. Epub 2018 Aug 3.

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC.

Objective: To assess distribution of alveolar-interstitial syndrome (AIS) detected by lung ultrasound (LUS) compared to thoracic radiographs (TXR).

Design: Prospective study.

Setting: University teaching hospital. Read More

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http://dx.doi.org/10.1111/vec.12750DOI Listing
September 2018
3 Reads

Blast from the past: a novel complication of bronchopulmonary dysplasia.

BMJ Case Rep 2018 Jul 30;2018. Epub 2018 Jul 30.

Department of Pulmonology/Critical Care, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/bcr-2018-225005DOI Listing
July 2018
3 Reads

Salvage therapies for refractory hypoxemia in ARDS.

Respir Med 2018 08 3;141:150-158. Epub 2018 Jul 3.

Pulmonary, Critical Care and Sleep Medicine, U C San Diego School of Medicine, USA. Electronic address:

Acute Respiratory Distress Syndrome (ARDS) is a condition of varied etiology characterized by the acute onset (within 1 week of the inciting event) of hypoxemia, reduced lung compliance, diffuse lung inflammation and bilateral opacities on chest imaging attributable to noncardiogenic (increased permeability) pulmonary edema. Although multi-organ failure is the most common cause of death in ARDS, an estimated 10-15% of the deaths in ARDS are caused due to refractory hypoxemia, i.e. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09546111183022
Publisher Site
http://dx.doi.org/10.1016/j.rmed.2018.06.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186150PMC
August 2018
25 Reads

Radiolabelled leucocytes in human pulmonary disease.

Br Med Bull 2018 09;127(1):69-82

Department of Nuclear Medicine, Brighton and Sussex Medical School, Brighton, East Sussex, UK.

Introduction: Radionuclides for leucocyte kinetic studies have progressed from non-gamma emitting cell-labelling radionuclides through gamma emitting nuclides that allow imaging of leucocyte kinetics, to the next goal of positron emission tomography (PET).

Sources Of Data: Mostly the authors' own studies, following on from studies of the early pioneers.

Areas Of Controversy: From early imaging studies, it appeared that the majority of the marginated granulocyte pool was located in the lungs. Read More

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http://dx.doi.org/10.1093/bmb/ldy022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312042PMC
September 2018
11 Reads

Regulatory T Cells and Acute Lung Injury: Cytokines, Uncontrolled Inflammation, and Therapeutic Implications.

Front Immunol 2018 9;9:1545. Epub 2018 Jul 9.

Department of Emergency and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Acute respiratory distress syndrome/acute lung injury (ALI) was described in 1967. The uncontrolled inflammation is a central issue of the syndrome. The regulatory T cells (Tregs), formerly known as suppressor T cells, are a subpopulation of T cells. Read More

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http://dx.doi.org/10.3389/fimmu.2018.01545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046379PMC
July 2018
6 Reads

Etoposide and Corticosteroid Combination Therapy Improves Acute Respiratory Distress Syndrome in Mice.

Shock 2018 Jul 19. Epub 2018 Jul 19.

Department of Infection Control and Laboratory Diagnostics, Internal Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.

Excessive inflammation reactions with a cytokine storm in the lungs have historically been thought as the primary cause of fatal acute respiratory distress syndrome (ARDS). However, interruption of inflammatory cytokine activation failed to attenuate ARDS, suggesting that other therapies are required to treat this illness and improve survival. Etoposide (ET), a cytotoxic agent, and prednisolone (PSL), a corticosteroid with strong anti-inflammatory activity, have been used to treat other disease involving similar cytokine-activated macrophages and hemophagocytic activity. Read More

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http://dx.doi.org/10.1097/SHK.0000000000001231DOI Listing
July 2018
4 Reads

[Analysis of 15 cases of avian influenza virus (H7N9) infection].

Zhonghua Jie He He Hu Xi Za Zhi 2018 Jul;41(7):534-538

Taizhou People's Hospital, Taizhou 225300, China.

To describe the clinical, chest imaging, pathological manifestations and therapeutic experience of human infection with A/H7N9 virus. The features of 15 laboratory-confirmed cases of human infection with A/H7N9 virus in Taizhou, Jiangsu Province were retrospectively analyzed. The 15 patients with confirmed viral pneumonia included 12 males and 3 females, with a median age of 61 years(ranging from 33 to 81 years). Read More

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http://dx.doi.org/10.3760/cma.j.issn.1001-0939.2018.07.006DOI Listing
July 2018
22 Reads