54,182 results match your criteria Image-Guided Surgery


Accuracy of patient-specific implants and additive-manufactured surgical splints in orthognathic surgery - A three-dimensional retrospective study.

J Craniomaxillofac Surg 2019 Mar 2. Epub 2019 Mar 2.

University of Heidelberg, Department of Oral and Maxillofacial Surgery, (Head of Department: Prof. Dr. Dr. J. Hoffmann), Im Neuenheimer Feld 400, D-69120, Heidelberg, Germany.

Introduction: Because of the many limitations of conventional surgery planning for the treatment of orthognathic deformities, as well as advancements in computer-assisted planning, there is an urgent need for technical devices that transfer the surgical plan into the operating theatre. In this regard, additive-manufactured, patient-specific implants (PSI) and additive-manufactured interocclusal splints represent promising approaches. The aim of this retrospective study was to compare the accuracy of these two devices, with regard to preoperative virtual treatment planning for maxillary Le-Fort I advancement surgery using IPS CaseDesigner, and based on a new analysis method without the use of landmarks. Read More

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http://dx.doi.org/10.1016/j.jcms.2019.02.011DOI Listing

Posterior tibial slope modification in osteoarthritis knees with different ACL conditions: Cadaveric study of fixed-bearing UKA.

J Orthop Surg (Hong Kong) 2019 May-Aug;27(2):2309499019836286

Department of Orthopaedic Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Unicompartmental knee arthroplasty (UKA) in anterior cruciate ligament deficiency (ACLD) has been debated for decades after the development of highly cross-linked polyethylene. This study aims to evaluate the effect of posterior tibial slope on restoring adequate knee stability and flexion after UKA in patients with ACLD. A total of 15 fresh cadaveric knees were divided into three groups: intact ACL, partial ACLD, and complete ACLD. Read More

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http://dx.doi.org/10.1177/2309499019836286DOI Listing

Stereotactic Body Radiotherapy - Current Indications.

Klin Onkol 2019 ;32(1):10-24

Background: Stereotactic body radiotherapy (SBRT) is used to treat localized tumor lesions and consists of applying high doses of radiation to a small number of fractions using specially equipped linear accelerators, modern immobilization devices, and imaging methods, which are considered special, advanced techniques in modern day radiotherapy. SBRT is a very well tolerated, non-invasive, short-term treatment that does not require hospitalization or any complicated preparation. Compared to standard radiotherapy techniques, SBRT allows, due to its precision, significantly higher doses to be applied to the target with less damage to surrounding healthy tissues. Read More

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http://dx.doi.org/10.14735/amko201910DOI Listing
January 2019

Navigated versus Conventional Technique in High Tibial Osteotomy: A Meta-Analysis Focusing on Weight Bearing Effect.

Knee Surg Relat Res 2019 Mar 18. Epub 2019 Mar 18.

Department of Orthopedic Surgery, Gachon University Gil Medical Center, Incheon, Korea.

Purpose: : We aimed to determine whether navigated opening wedge high tibial osteotomy (HTO) is superior to the conventional technique in terms of accuracy of the coronal and sagittal alignment correction, functional outcome, and operative time.

Methods: : Studies comparing navigated and conventional HTO were included in this meta-analysis. We compared the incidence of radiological outliers in coronal alignment and tibial slope maintenance, mean differences in functional outcome scales, and operative time. Read More

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http://dx.doi.org/10.5792/ksrr.17.090DOI Listing

Assessment of sympathetic reinnervation after cardiac transplantation using hybrid cardiac PET/MRI: A pilot study.

J Magn Reson Imaging 2019 Mar 20. Epub 2019 Mar 20.

Department of Biomedical Imaging and Image-Guided Therapy, Division of Cardiovascular and Interventional Radiology, Medical University of Vienna, Vienna, Austria.

Background: Sympathetic reinnervation after heart transplantation (HTX) is a known phenomenon, which has an impact on patient heart rate variability and exercise capacity. The impact of reinnervation on myocardial structure has not been evaluated yet.

Propose: To evaluate the feasibility of simultaneous imaging of cardiac reinnervation and cardiac structure using a hybrid PET/MRI system. Read More

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http://dx.doi.org/10.1002/jmri.26722DOI Listing

Machine learning in medicine: a practical introduction.

BMC Med Res Methodol 2019 Mar 19;19(1):64. Epub 2019 Mar 19.

Department of Surgery, Harvard Medical School, 25 Shattuck Street, Boston, 01225, Massachusetts, USA.

Background: Following visible successes on a wide range of predictive tasks, machine learning techniques are attracting substantial interest from medical researchers and clinicians. We address the need for capacity development in this area by providing a conceptual introduction to machine learning alongside a practical guide to developing and evaluating predictive algorithms using freely-available open source software and public domain data.

Methods: We demonstrate the use of machine learning techniques by developing three predictive models for cancer diagnosis using descriptions of nuclei sampled from breast masses. Read More

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http://dx.doi.org/10.1186/s12874-019-0681-4DOI Listing
March 2019
1 Read

Computer-assisted surgery in total knee replacement: advantages, surgical procedure and review of the literature.

Acta Biomed 2019 Jan 22;90(1):16-23. Epub 2019 Jan 22.

Gaetano Pini-CTO, Milano.

Introduction: Total knee replacement (TKR) is one of the most frequent orthopaedic procedures performed every year. At the same time 20% of patients who underwent TKR are not satisfied with the outcome. The reasons are unknown; we think that a mechanical alignment beyond 3° of varus-valgus can represent the most important cause of failure of TKR and consequently patient dissatisfaction. Read More

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http://dx.doi.org/10.23750/abm.v90i1.6319DOI Listing
January 2019

Benefits of Robotic Camera Assistance in Minimally Invasive Bariatric Procedures: Prospective Clinical Trial Using a Joystick-Guided Camera-Holder.

Surg Technol Int 2019 Mar 18;34. Epub 2019 Mar 18.

Department of General and Visceral Surgery, Hospital Bietigheim-Vaihingen, Bietigheim-Vaihingen, Germany.

Background: While minimally invasive surgery is a growing sector in medicine, camera assistance remains a problem. Especially in bariatric surgery, the assistant holding the camera faces certain challenges. Furthermore, unless the surgeon controls the camera movement themselves, they will be challenged by an unstable image. Read More

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Deformable multimodal registration for navigation in beating-heart cardiac surgery.

Int J Comput Assist Radiol Surg 2019 Mar 19. Epub 2019 Mar 19.

Queen's University, Kingston, K7L 3N6, Canada.

Purpose: Minimally invasive beating-heart surgery is currently performed using endoscopes and without navigation. Registration of intraoperative ultrasound to a preoperative cardiac CT scan is a valuable step toward image-guided navigation.

Methods: The registration was achieved by first extracting a representative point set from each ultrasound image in the sequence using a deformable registration. Read More

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http://dx.doi.org/10.1007/s11548-019-01932-2DOI Listing

Toward an automatic preoperative pipeline for image-guided temporal bone surgery.

Int J Comput Assist Radiol Surg 2019 Mar 19. Epub 2019 Mar 19.

Department of Computer Science, Technische Universität Darmstadt, Darmstadt, Germany.

Purpose: Minimally invasive surgery is often built upon a time-consuming preoperative step consisting of segmentation and trajectory planning. At the temporal bone, a complete automation of these two tasks might lead to faster interventions and more reproducible results, benefiting clinical workflow and patient health.

Methods: We propose an automatic segmentation and trajectory planning pipeline for image-guided interventions at the temporal bone. Read More

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http://dx.doi.org/10.1007/s11548-019-01937-xDOI Listing

Objective and subjective comparison of virtual monoenergetic vs. polychromatic images in patients with pancreatic ductal adenocarcinoma.

Eur Radiol 2019 Mar 19. Epub 2019 Mar 19.

Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Objectives: The aim of this study was to assess the objective and subjective image characteristics of monoenergetic images (MEI[+]), using a noise-optimized algorithm at different kiloelectron volts (keV) compared to polyenergetic images (PEI), in patients with pancreatic ductal adenocarcinoma (PDAC).

Methods: This retrospective, institutional review board-approved study included 45 patients (18 male, 27 female; mean age 66 years; range, 42-96 years) with PDAC who had undergone a dual-energy CT (DECT) of the abdomen for staging. One standard polyenergetic image (PEI) and five MEI(+) images in 10-keV intervals, ranging from 40 to 80 keV, were reconstructed. Read More

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http://dx.doi.org/10.1007/s00330-019-06116-9DOI Listing

Liposome-based probes for molecular imaging: from basic research to the bedside.

Nanoscale 2019 Mar 19. Epub 2019 Mar 19.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

Molecular imaging is very important in disease diagnosis and prognosis. Liposomes are excellent carriers for different types of molecular imaging probes. In this work, we summarize current developments in liposome-based probes used for molecular imaging and their applications in image-guided drug delivery and tumour surgery, including computed tomography (CT), ultrasound imaging (USI), magnetic resonance imaging (MRI), positron emission tomography (PET), fluorescence imaging (FLI) and photoacoustic imaging (PAI). Read More

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http://dx.doi.org/10.1039/c9nr00207cDOI Listing

[Feasibility analysis of predicting expression of Ki67 in pancreatic cystic neoplasm based on radiomics].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2019 Feb;36(1):1-6

Department of Electronic Engineering, Fudan University, Shanghai 200433, P.R.China;Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention of Shanghai, Shanghai 200433, P.R.China.

This study aims to predict expression of Ki67 molecular marker in pancreatic cystic neoplasm using radiomics. We firstly manually segmented tumor area in multi-detector computed tomography (MDCT) images. Then 409 high-throughput features were automatically extracted and the least absolute shrinkage selection operator (LASSO) regression model was used for feature selection. Read More

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http://dx.doi.org/10.7507/1001-5515.201805014DOI Listing
February 2019

Short-term outcomes of laparoscopic repeat liver resection after open liver resection: a systematic review.

Surg Endosc 2019 Mar 18. Epub 2019 Mar 18.

Institut de Recherche Contre les Cancers de l'Appareil Digestif (IRCAD), Strasbourg, France.

Background: Laparoscopic repeat liver resection (LRLR) still represents a challenge for surgeons especially in case with previous open liver surgery. The aim of the study is to perform a systematic review of the current literature to investigate the feasibility of LRLR after open liver resection (OLR) for liver diseases.

Methods: A computerized search was performed for all English language studies evaluating LRLR. Read More

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http://link.springer.com/10.1007/s00464-019-06754-6
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http://dx.doi.org/10.1007/s00464-019-06754-6DOI Listing
March 2019
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Short-term functional outcomes of computer assisted navigated high tibial osteotomy.

J Orthop 2019 Mar-Apr;16(2):166-170. Epub 2019 Feb 28.

Division of Orthopedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.

Purpose: High tibial osteotomy (HTO) is a surgical procedure performed on patients with knee osteoarthritis (OA). Computer assisted navigated high tibial osteotomy (CAN-HTO) may result in improved outcomes for patients undergoing this procedure.

Methods: Retrospective study involving patients undergoing CAN-HTO. Read More

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http://dx.doi.org/10.1016/j.jor.2019.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402292PMC
February 2019

Laparoscopy-assisted transgastric endoscopic retrograde cholangiopancreatography: Preliminary experience and technique description.

J Visc Surg 2019 Mar 15. Epub 2019 Mar 15.

IRCAD, Research institute against cancer of the digestive system, 67000 Strasbourg, France; IHU-Strasbourg, institute for image-guided surgery, 67000 Strasbourg, France; Department of digestive surgery, university hospital of Strasbourg, 67000 Strasbourg, France.

Introduction: Common bile duct lithiasis after Roux-en-Y gastric bypass (RYGB) or upper gastrointestinal stenosis has become a challenging problem nowadays, especially as obesity surgery is increasing. In this study, we assess the feasibility and performance of laparoscopy-assisted transgastric endoscopic retrograde cholangiopancreatography (LAERCP) and describe its technique.

Methods: A retrospective review of a prospectively collected database of consecutive patients undergoing a LAERCP between February 2014 and May 2015 was performed at a single institution. Read More

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http://dx.doi.org/10.1016/j.jviscsurg.2019.02.009DOI Listing

Joint-preserving tumour resection around the knee with allograft reconstruction using three-dimensional preoperative planning and patient-specific instruments.

Knee 2019 Mar 15. Epub 2019 Mar 15.

Balgrist University Hospital, Department of Orthopaedics, University of Zurich, Forchstrasse 340, 8008 Zurich, Switzerland.

Background: The region around the knee joint is a common location of malignant bone tumours. Limb salvage procedures, whenever possible, are preferred to amputation. Allograft reconstruction is an accepted procedure to restore large bone defects. Read More

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http://dx.doi.org/10.1016/j.knee.2019.02.015DOI Listing

Anisotropic non-rigid Iterative Closest Point Algorithm for respiratory motion abdominal surface matching.

Biomed Eng Online 2019 Mar 18;18(1):25. Epub 2019 Mar 18.

Biomedical Engineering, Silesian University of Technology, 40 Roosevelta, 41-800, Zabrze, Poland.

Surface registration is a one of the crucial and actual problems of computer aided surgery. This paper presents the modification of the non-rigid Iterative Closest Point Algorithm which takes into account an anisotropic noise model and landmarks as guided correspondence at the transformation step in every iteration. The presented approach was validated on human abdominal briefing surface data from a time-of-flight camera. Read More

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http://dx.doi.org/10.1186/s12938-019-0643-4DOI Listing

Coronal plane laxity of valgus osteoarthritic knee.

J Orthop Surg (Hong Kong) 2019 Jan-Apr;27(1):2309499019833058

3 School of Biomedical Engineering, Queensland University of Technology, Brisbane, Australia.

Introduction: Balanced soft tissues are important to total knee arthroplasty (TKA) outcomes. Surgical algorithms for balancing are potentially varied in varus and valgus osteoarthritic (OA) knees. While coronal plane varus knee laxity has been documented, no study has objectively defined the medial and lateral laxity of the valgus OA knee. Read More

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http://dx.doi.org/10.1177/2309499019833058DOI Listing

Image-Guided Percutaneous Gastrostomy Tube Placement is Safe in Patients Requiring Aspirin 325 mg.

Acad Radiol 2019 Mar 14. Epub 2019 Mar 14.

Department of Radiology, Duke University School of Medicine, Durham, North Carolina.

Rationale And Objectives: Requests for gastrostomy tube placement in patients on aspirin (ASA) 325 mg are common, particularly in patients following reconstructive surgery for head and neck cancer, but periprocedural guidelines and recommendations regarding management of high dose aspirin are inconsistent. The purpose of this study was to assess the bleeding risk of percutaneous gastrostomy tube placement in patients on ASA 325 mg.

Materials And Methods: This retrospective study of 213 patients who underwent image-guided "push" percutaneous gastrostomy tube placement compared rates of significant bleeding and other secondary outcomes (including all-cause mortality within 30 days, procedure-related mortality, bowel perforation, abdominal abscess, peritonitis, aspiration pneumonia, intraprocedural airway complications, and tube dislodgement) between patients maintained on ASA 325 mg and patients not on antiplatelet or anticoagulation therapy. Read More

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http://dx.doi.org/10.1016/j.acra.2019.02.008DOI Listing

Removal of intraconal bullet through endoscopic transnasal surgery with image-guided navigation system 8 months after injury: a case report.

J Med Case Rep 2019 Mar 17;13(1):65. Epub 2019 Mar 17.

Division of Allergy and Rhinology, Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkla, 90110, Thailand.

Background: Lodgment of a bullet within the orbit is uncommon. The decision to remove these objects poses a challenge to surgeons due to a high risk of complications. Currently, endoscopic transnasal surgery with navigator assistance facilitates the localization of foreign bodies allowing their safe removal with minimal surrounding tissue damage or optic nerve injury. Read More

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http://dx.doi.org/10.1186/s13256-019-2007-xDOI Listing

A dual-modality linker enables site-specific conjugation of antibody fragments for F-immunoPET and fluorescence imaging.

J Nucl Med 2019 Mar 15. Epub 2019 Mar 15.

Beckman Research Institute of the City of Hope, United States.

Antibody-based dual-modality (PET/fluorescence) imaging enables both pre-surgery antigen-specific immunoPET for non-invasive whole-body evaluation and intra-operative fluorescence for visualization of superficial tissue layers for image guided surgery. We developed a universal dual-modality linker (DML) that facilitates 1) site-specific conjugation to a cysteine residue bearing antibody fragment; 2) introduction of a commercially available fluorescent dye (via amine-reactive prosthetic group); 3) rapid and efficient radiolabeling via click chemistry with F-labeled trans-cyclooctene (F-TCO). To generate a dual-modality antibody fragment based imaging agent, the DML was labeled with the far-red dye sulfo-Cy5 (sCy5), site-specifically conjugated to the C-terminal cysteine of the anti-prostate stem cell antigen (PSCA) cys-diabody A2 (A2cDb), and subsequently radiolabeled by click chemistry with F-TCO. Read More

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http://dx.doi.org/10.2967/jnumed.118.223560DOI Listing

Trends and challenges for the clinical adoption of fluorescence-guided surgery.

J Nucl Med 2019 Mar 15. Epub 2019 Mar 15.

Barrow Neurological Institute, United States.

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http://dx.doi.org/10.2967/jnumed.119.226795DOI Listing

Gamma Knife Radiosurgery for the Management of Greater than 15 Cerebral Metastases.

World Neurosurg 2019 Mar 12. Epub 2019 Mar 12.

Department of Neurological Surgery and the Center for Image-Guided Neurosurgery, Pittsburgh, PA.

Background: The number of metastases that can be treated safely and effectively with Gamma Knife® stereotactic radiosurgery (GKSRS) remains controversial despite continuing evidence to support its expanded utilization. We endeavored to elucidate the survival outcomes for patients who presented with ≥15 brain metastases at the time of initial SRS.

Methods: This retrospective analysis reviewed patients treated for ≥15 brain metastases originating from breast cancer, lung cancer, or melanoma. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.019DOI Listing
March 2019
1 Read

Commentary: Minimally Invasive Parafascicular Surgery for Resection of Cerebral Cavernous Malformations Utilizing Image-Guided BrainPath System.

Oper Neurosurg (Hagerstown) 2019 Mar 15. Epub 2019 Mar 15.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/ons/opz033DOI Listing

The Accuracy of Alignment Determined by Patient-Specific Instrumentation System in Total Knee Arthroplasty.

Knee Surg Relat Res 2019 Mar;31(1):19-24

Medical Engineering, Konyang University College of Medicine, Daejeon, Korea.

Purpose: The aim of this study is to assess the accuracy of alignment determined by patient-specific instrumentation system in total knee arthroplasty(TKA).

Materials And Methods: Twenty-seven TKAs using patient-specific instrument were reviewed. The intraoperative pin location determined by the patient-specific guide was recorded using imageless navigation software. Read More

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http://dx.doi.org/10.5792/ksrr.18.038DOI Listing

Automatic segmentation of bone surfaces from ultrasound using a filter-layer-guided CNN.

Int J Comput Assist Radiol Surg 2019 Mar 13. Epub 2019 Mar 13.

Department of Biomedical Engineering, Rutgers University, Piscataway, NJ, USA.

Purpose: Ultrasound (US) provides real-time, two-/three-dimensional safe imaging. Due to these capabilities, it is considered a safe alternative to intra-operative fluoroscopy in various computer-assisted orthopedic surgery (CAOS) procedures. However, interpretation of the collected bone US data is difficult due to high levels of noise, various imaging artifacts, and bone surfaces response appearing several millimeters (mm) in thickness. Read More

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http://dx.doi.org/10.1007/s11548-019-01934-0DOI Listing

Transrectal and transvaginal catheter drainages and aspirations for management of pelvic fluid collections: technique, technical success rates, and outcomes in 150 patients.

Abdom Radiol (NY) 2019 Mar 13. Epub 2019 Mar 13.

Department of Radiology, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71130, USA.

Purpose: To evaluate outcomes of image-guided transrectal/transvaginal (TR/TV) drainage for symptomatic pelvic fluid collections (SPFCs).

Materials And Methods: Single-center retrospective study of 150 consecutive patients (36 males, 114 females, average age 41 years) who underwent attempted TR/TV drainages of SPFCs during an 11-year, 5-month period. All patients presented with pain and had SPFCs with rectal or vaginal contact on preceding diagnostic CT. Read More

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http://dx.doi.org/10.1007/s00261-019-01974-9DOI Listing
March 2019
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Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Targeted and Image-Guided Photodynamic Therapy of Hepatocellular Carcinoma.

Theranostics 2019 12;9(5):1264-1279. Epub 2019 Feb 12.

Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Photosensitizer (PS) serves as the central element of photodynamic therapy (PDT). The use of common nanoparticles (NPs) for PDT has typically been rendered less effective by the undesirable aggregation-caused quenching (ACQ) effect, resulting in quenched fluorescence and reduced reactive oxygen species (ROS) generation that diminish the imaging quality and PDT efficacy. To overcome the ACQ effect and to enhance the overall efficacy of PDT, herein, integrin αβ-targeted organic nanodots for image-guided PDT were designed and synthesized based on a red emissive aggregation-induced emission (AIE) PS. Read More

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http://dx.doi.org/10.7150/thno.29101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401505PMC
February 2019

Zwitterionic near-infrared fluorophore-conjugated epidermal growth factor for fast, real-time, and target-cell-specific cancer imaging.

Theranostics 2019 30;9(4):1085-1095. Epub 2019 Jan 30.

Research Institute, National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi 10408, Republic of Korea.

Epidermal growth factor receptor (EGFR) is overexpressed in many types of cancers, which is associated with metastatic potential and poor prognosis in cancer patients. Therefore, development of EGFR-targeted sensitive imaging probes has been a challenge in tumor targeting, image-guided cancer surgery, patient-selective anti-EGFR therapy, and efficient targeted therapies. : We synthesized a zwitterionic near-infrared fluorophore (ATTO655)-conjugated epidermal growth factor (EGF) as a novel activatable molecular probe. Read More

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http://dx.doi.org/10.7150/thno.29719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401407PMC
January 2019

Three-Dimensional Assessment of Morphological Changes Following Nasoalveolar Molding Therapy in Cleft Lip and Palate Patients: A Case Report.

Dent J (Basel) 2019 Mar 7;7(1). Epub 2019 Mar 7.

Institute of Dentistry and Maxillofacial Surgery, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli, 8, 00168 Roma, Italy.

The applications of computer-guided technologies for three-dimensional image analysis provide a unique opportunity to quantify the morphological dimensional changes of the face in a practical and convenient way. Symmetry of the nasolabial area is one of the main factors of facial attractiveness as well as being the main objective of the treatment of cleft lip and palate (CLP). Technological advances in computer-guided visualization modes and their applications to three-dimensional stereophotogrammetry provide more practical opportunities and alternatives for facial analysis. Read More

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http://dx.doi.org/10.3390/dj7010027DOI Listing

On the feasibility of transperineal 3D ultrasound image guidance for robotic radical prostatectomy.

Int J Comput Assist Radiol Surg 2019 Mar 13. Epub 2019 Mar 13.

Department of Electrical and Computer Engineering, University of British Columbia, 2332 Main Mall, Vancouver, BC, V6T 1Z4, Canada.

Purpose: Prostate cancer is the most prevalent form of male-specific cancers. Robot-assisted laparoscopic radical prostatectomy (RALRP) using the da Vinci surgical robot has become the gold-standard treatment for organ-confined prostate cancer. To improve intraoperative visualization of anatomical structures, many groups have developed techniques integrating transrectal ultrasound (TRUS) into the surgical workflow. Read More

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http://link.springer.com/10.1007/s11548-019-01938-w
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http://dx.doi.org/10.1007/s11548-019-01938-wDOI Listing
March 2019
3 Reads

Interactive Flying Frustums (IFFs): spatially aware surgical data visualization.

Int J Comput Assist Radiol Surg 2019 Mar 12. Epub 2019 Mar 12.

Computer Aided Medical Procedures, Johns Hopkins University, Baltimore, MD, USA.

Purpose: As the trend toward minimally invasive and percutaneous interventions continues, the importance of appropriate surgical data visualization becomes more evident. Ineffective interventional data display techniques that yield poor ergonomics that hinder hand-eye coordination, and therefore promote frustration which can compromise on-task performance up to adverse outcome. A very common example of ineffective visualization is monitors attached to the base of mobile C-arm X-ray systems. Read More

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http://link.springer.com/10.1007/s11548-019-01943-z
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http://dx.doi.org/10.1007/s11548-019-01943-zDOI Listing
March 2019
2 Reads

Application of computer-assisted navigation in treating congenital maxillomandibular syngnathia: A case report.

World J Clin Cases 2019 Mar;7(5):650-655

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.

Background: Congenital maxillomandibular syngnathia is an extremely rare disorder characterized by craniofacial malformations and inability to open the mouth adequately, which leads to problems with feeding, swallowing, and breathing as well as temporomandibular joint ankylosis. The main goal of the surgery is to release the ankylosis, establish functioning mandible, and prevent re-fusion. However, surgical procedures for this disease are rarely reported. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i5.650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406194PMC

Concomitant dose escalation with image-guided Tomotherapy in locally advanced mid-low rectal cancer: a single-center study.

Cancer Manag Res 2019 15;11:1579-1586. Epub 2019 Feb 15.

Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China,

Purpose: The purpose of this study was to evaluate the efficacy and toxicity of concomitant dose-escalated Tomotherapy in locally advanced mid-low rectal cancer.

Patients And Methods: Patients with locally advanced (T3/T4 or N+), low-mid (≤10 cm from anal verge) rectal carcinoma treated with neoadjuvant chemoradiotherapy followed by surgery between May 2012 and October 2017 in Peking Union Medical College Hospital were included in this study. A dose of 45/50 Gy in 25 fractions was delivered to the pelvis with Tomotherapy, and 55 Gy was prescribed for the primary tumor with a simultaneous, integrated boost. Read More

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http://dx.doi.org/10.2147/CMAR.S193657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388983PMC
February 2019
1 Read

Accuracy of Distinguishing Atypical Ductal Hyperplasia From Ductal Carcinoma In Situ With Convolutional Neural Network-Based Machine Learning Approach Using Mammographic Image Data.

AJR Am J Roentgenol 2019 Mar 12:1-6. Epub 2019 Mar 12.

4 Department of Medical Physics, Columbia University Medical Center, New York, NY.

Objective: The purpose of this study was to test the hypothesis that convolutional neural networks can be used to predict which patients with pure atypical ductal hyperplasia (ADH) may be safely monitored rather than undergo surgery.

Materials And Methods: A total of 298 unique images from 149 patients were used for our convolutional neural network algorithm. A total of 134 images from 67 patients with ADH that had been diagnosed by stereotactic-guided biopsy of calcifications but had not been upgraded to ductal carcinoma in situ or invasive cancer at the time of surgical excision. Read More

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http://dx.doi.org/10.2214/AJR.18.20250DOI Listing

Can Impedance-pH Testing on Medications Reliably Identify Patients with GERD as Defined by Pathologic Esophageal Acid Exposure off Medications?

J Gastrointest Surg 2019 Mar 11. Epub 2019 Mar 11.

Department of Surgery, Providence Portland Medical Center, Portland, OR, USA.

Introduction: Impedance-pH testing (MII-pH) while patients are on acid suppression medications is frequently used to evaluate persistent reflux symptoms. The aim of this study was to determine whether MII-pH on medications can reliably identify patients with gastroesophageal reflux disease (GERD) as defined by pathologic esophageal acid exposure off medications, and to determine if there is a threshold of total reflux episodes on medications where pH testing off medications may be unnecessary.

Methods: A retrospective review identified all patients between 1/2010 and 4/2017 who underwent MII-pH testing on PPI medications and subsequently had pH testing off medications. Read More

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http://dx.doi.org/10.1007/s11605-019-04148-6DOI Listing
March 2019
1 Read

Current State of Tumor Ablation Therapies.

Dig Dis Sci 2019 Mar 12. Epub 2019 Mar 12.

Division of Interventional Radiology, Department of Radiology, VCU Medical Center, Virginia Commonwealth University, Main Hospital. 1250 E. Marshall St. Room 3-407B1, Richmond, VA, 23219, USA.

The most common primary liver malignancy, hepatocellular carcinoma (HCC), has a high likelihood of mortality, and much effort into early detection and treatment has occurred. Multiple staging systems have surfaced of which some guide treatment. Curative intent is a goal of early-staged HCC treatment, and this can be achieved with surgical resection, liver transplantation, and minimally invasive percutaneous therapies such as tumor ablation. Read More

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http://dx.doi.org/10.1007/s10620-019-05514-9DOI Listing
March 2019
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Novel method for preventing cyclorotation in Ziemer Femto LDV Z8 femtosecond laser-assisted cataract surgery with Verion image-guided system.

Clin Ophthalmol 2019 20;13:415-419. Epub 2019 Feb 20.

Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan, Republic of China,

Purpose: To investigate the feasibility of a new method involving the use of the Verion image-guided system in preventing cyclorotation during femtosecond laser-assisted cataract surgery (FLACS).

Patients: Our preliminary data included details of 24 consecutive patients. All patients underwent cataract surgery at Universal Eye Center, Zhong-Li, Taiwan, between December 2016 and January 2017. Read More

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http://dx.doi.org/10.2147/OPTH.S177219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387593PMC
February 2019

Research Priorities in Pelvic Venous Disorders in Women: Recommendations from a Multidisciplinary Research Consensus Panel.

J Vasc Interv Radiol 2019 Mar 8. Epub 2019 Mar 8.

Connecticut Image-Guided Surgery, Fairfield, Connecticut.

Pelvic venous disorders (PeVDs) in women can present with chronic pelvic pain, lower-extremity and vulvar varicosities, lower-extremity swelling and pain, and left-flank pain and hematuria. Multiple evidence gaps exist related to PeVDs with the consequence that nonvascular specialists rarely consider the diagnosis. Recognizing this, the Society of Interventional Radiology Foundation funded a Research Consensus Panel to prioritize a research agenda to address these gaps. Read More

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http://dx.doi.org/10.1016/j.jvir.2018.10.008DOI Listing

Computed tomography-guided navigation assisted drainage for inaccessible deep neck abscess: A case report.

Medicine (Baltimore) 2019 Mar;98(10):e14674

Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea.

Rationale: Deep neck infections (DNIs) in the head and neck area are difficult to treat due to the anatomical complexity of the cervical region. Since inflammation causes changes in anatomy, it is often difficult to find the exact location of the abscess, which leads to failed surgical drainage.

Patient Concern: A 76-year-old female patient was referred to our clinic with trismus and right-side facial swelling. Read More

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http://dx.doi.org/10.1097/MD.0000000000014674DOI Listing
March 2019
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Safety and efficacy of computed tomography-guided dye localization using patent blue V for single lung nodule for video-assisted thoracoscopic surgery: a retrospective study.

Ann Transl Med 2019 Jan;7(2):28

Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taichung, Taiwan.

Background: For invisible or impalpable lung nodules, video-assisted thoracoscopic surgery (VATS) has some limitations; some preoperative localization has been developed to overcome this limitation. This study aimed to assess the safety and efficacy of preoperative computed tomography (CT)-guided localization with patent blue V dye.

Methods: In this retrospective study, we examined patients with solitary pulmonary nodule undergoing preoperative CT-guided patent blue V dye localization from 2013 to 2015. Read More

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http://dx.doi.org/10.21037/atm.2019.01.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381270PMC
January 2019

High resolution, 3-dimensional Ferumoxytol-enhanced cardiovascular magnetic resonance venography in central venous occlusion.

J Cardiovasc Magn Reson 2019 Mar 11;21(1):17. Epub 2019 Mar 11.

Diagnostic Cardiovascular Imaging Laboratory, University of California, Los Angeles, Peter V. Ueberroth Building Suite 3371, 10945 Le Conte Ave, Los Angeles, 90095-7206, CA, USA.

Background: Although cardiovascular magnetic resonance venography (CMRV) is generally regarded as the technique of choice for imaging the central veins, conventional CMRV is not ideal. Gadolinium-based contrast agents (GBCA) are less suited to steady state venous imaging than to first pass arterial imaging and they may be contraindicated in patients with renal impairment where evaluation of venous anatomy is frequently required. We aim to evaluate the diagnostic performance of 3-dimensional (3D) ferumoxytol-enhanced CMRV (FE-CMRV) for suspected central venous occlusion in patients with renal failure and to assess its clinical impact on patient management. Read More

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http://dx.doi.org/10.1186/s12968-019-0528-5DOI Listing
March 2019
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Image-Guided Transarterial Directed Delivery of Human Mesenchymal Stem Cells for Targeted Gastrointestinal Therapies in a Swine Model.

J Vasc Interv Radiol 2019 Mar 6. Epub 2019 Mar 6.

Department of Radiology and Imaging Sciences, Emory University, 201 Dowman Drive, Atlanta, GA 30322. Electronic address:

Purpose: To evaluate the feasibility of catheter-directed intra-arterial stem cell delivery of human mesenchymal stem cells (MSCs) to the small bowel in a porcine model.

Materials And Methods: The cranial mesenteric artery of 6 Yucatan minipigs was selectively catheterized under fluoroscopic guidance following cut-down and carotid artery access. A proximal jejunal branch artery was selectively catheterized for directed delivery of embolic microspheres (100-300 μm) or MSCs (0. Read More

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http://dx.doi.org/10.1016/j.jvir.2018.09.034DOI Listing

FDG-PET/MRI Imaging for the Management of Alveolar Echinococcosis: Initial Clinical Experience at a Reference Centre in Austria.

Trop Med Int Health 2019 Mar 9. Epub 2019 Mar 9.

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Austria.

Background: [ F]-2-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (FDG-PET/CT) imaging provides important information about the size and metabolic activity of lesions caused by Echinococcus multilocularis and is therefore recommended for the initial assessment and follow-up of human alveolar echinococcosis (AE). The introduction of positron emission tomography / magnetic resonance imaging (PET/MRI) into clinical practice in affluent health care systems provides an alternative dual imaging modality, which has not yet been evaluated for AE.

Objective: Here we describe the initial clinical experience with comparative PET/CT and PET/MR imaging in four human AE patients at an Austrian reference center. Read More

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http://dx.doi.org/10.1111/tmi.13228DOI Listing
March 2019
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Paget's Disease of Long Bones: Microstructural Analyses of Historical Bone Samples.

Calcif Tissue Int 2019 Mar 8. Epub 2019 Mar 8.

Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

Although Paget's disease of bone (PDB) is the second most common metabolic bone disease, there is only limited information about the microarchitecture of affected bones. Therefore, the aim of this study was to determine cortical and trabecular bone properties in clinically relevant locations by microcomputed tomography (µCT). Ten femora and ten tibiae affected by Paget's disease taken from the Natural History Museum Vienna were compared to 13 femora and 10 tibiae of non-affected body donors. Read More

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http://dx.doi.org/10.1007/s00223-019-00539-8DOI Listing
March 2019
3.272 Impact Factor

Proceedings - Pathways for Successful Translation of New Imaging Agents and Modalities: Phase III Studies.

J Nucl Med 2019 Mar 8. Epub 2019 Mar 8.

Washington University School of Medicine, United States.

Significant advances continue in the development of cancer-specific molecular imaging agents and modalities for diagnosing, staging, and treating various cancer types. For these advances to successfully translate to widespread clinical use, both regulatory approval by the U.S. Read More

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http://dx.doi.org/10.2967/jnumed.118.219824DOI Listing

Inoperable Pulmonary Carcinoid Tumors: Local Control Rates With Stereotactic Body Radiotherapy/Hypofractionated RT With Image-Guided Radiotherapy.

Clin Lung Cancer 2019 Feb 14. Epub 2019 Feb 14.

Department of Radiation Oncology, University of Rochester School of Medicine and Dentistry, Rochester, NY.

Introduction: Surgery is the standard of care for pulmonary carcinoid tumors; however, options for inoperable patients are few. We report the outcomes of inoperable pulmonary carcinoid patients treated with stereotactic body radiotherapy (SBRT).

Patients And Methods: From an institutional database, we retrospectively identified patients treated with SBRT for pulmonary carcinoid tumors from 2007 to 2017. Read More

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http://dx.doi.org/10.1016/j.cllc.2019.02.003DOI Listing
February 2019
1 Read

Accuracy of endoscopic ultrasound in rectal cancer and its use in transanal endoscopic microsurgery.

Minim Invasive Ther Allied Technol 2019 Mar 8:1-8. Epub 2019 Mar 8.

a Department of General Surgery , The Affiliated Hospital of Qingdao University , Qingdao , PR China.

Introduction: This study evaluated the accuracy of endoscopic ultrasound (EUS) for preoperative staging of rectal cancer and guiding the treatment of transanal endoscopic microsurgery (TEM) in early rectal cancer.

Material And Methods: One-hundred-twenty-six patients with rectal cancer were staged preoperatively using EUS and the results were compared with postoperative histopathology results. Radical surgeries, including low anterior resection (LAR), abdominal-perineal resection (APR) and Hartmann surgeries, were performed on patients with advanced rectal cancers, and TEM was performed on patients with stage T1. Read More

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http://dx.doi.org/10.1080/13645706.2019.1585373DOI Listing
March 2019
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Exoscope-Guided (VITOM 3D) Single-Stage Removal of Supratentorial Cavernous Angioma and Hemangioblastoma: 3-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2019 Mar 8. Epub 2019 Mar 8.

Division of Neurosurgery, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy.

This video shows an exoscope-guided single-stage resection with 3-dimensional technology of a supratentorial cavernoma and a supratentorial hemangioblastoma during the same surgical procedure. The patient is a 42-yr-old man with a history of generalized tonico-clonic seizures. Contrast-enhanced magnetic resonance (MR) revealed the presence of a left frontal cavernoma and a left T1 non-enhancing hypointese temporal lesion (hemangioblastoma). Read More

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http://dx.doi.org/10.1093/ons/opz010DOI Listing
March 2019
2 Reads