4,687 results match your criteria Idiopathic Intracranial Hypertension


[TREATMENT DILEMMAS IN FULMINANT INTRACRANIAL HYPERTENSION].

Harefuah 2019 Feb;158(2):96-100

Department of Ophthalmology, Barzilai University Medical Center, Israel.

Introduction: Fulminant intracranial hypertension is a rare, acute presentation of idiopathic intracranial hypertension with rapid and devastating visual loss that can lead to blindness. As vision deteriorates quickly and often irreversibly, prevention of further visual loss requires emergent treatment to decrease intracranial pressure. The case presented is that of an 18 years old male with new symptoms of headaches and visual obscurations that had rapid progressive visual loss with findings of severe bilateral swollen discs. Read More

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February 2019

Headaches in Idiopathic Intracranial Hypertension.

J Neuroophthalmol 2019 Mar;39(1):82-93

Departments of Neurology and Neurotherapeutics and Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas.

Background: Headache is the most common symptom of idiopathic intracranial hypertension (IIH) and may not resolve with intracranial pressure-lowering treatments. Many patients with IIH have a pre-existing history of migraine. Approximately two-thirds of patients with IIH continue to experience headaches after the other manifestations of the disorder resolve. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000777DOI Listing

Commentary: Idiopathic Intracranial Hypertension Without Papilledema (IIHWOP) in Chronic Refractory Headache.

Front Neurol 2019 29;10:39. Epub 2019 Jan 29.

Division of Neurology and Stroke Unit, Hospital A. Cardarelli, Naples, Italy.

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http://dx.doi.org/10.3389/fneur.2019.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361781PMC
January 2019
1 Read

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics.

JCI Insight 2019 Feb 12. Epub 2019 Feb 12.

Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, characterized by elevated intracranial pressure frequently manifesting with chronic headaches and visual loss. Similar to polycystic ovary syndrome (PCOS), IIH predominantly affects obese women of reproductive age. In this study, we comprehensively examined the systemic and cerebrospinal fluid (CSF) androgen metabolome in women with IIH in comparison to sex-, body mass index- and age-matched control groups with either simple obesity and PCOS, i. Read More

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http://dx.doi.org/10.1172/jci.insight.125348DOI Listing
February 2019
1 Read

Do Most Patients With a Spontaneous Cerebrospinal Fluid Leak Have Idiopathic Intracranial Hypertension?

J Neuroophthalmol 2019 Feb 8. Epub 2019 Feb 8.

Departments of Ophthalmology (SB, NJN, and VB), Otolaryngology-Head and Neck Surgery (JML), Radiology and Imaging Sciences (AMS), Neurological Surgery (NMO and NJN), and Neurology (NJN and VB), Emory University School of Medicine, Atlanta, Georgia.

Background: The association between cerebrospinal fluid (CSF) leaks at the skull base and raised intracranial pressure (ICP) has been reported since the 1960s. It has been suggested that spontaneous CSF leaks might represent a variant of idiopathic intracranial hypertension (IIH). We review the evidence regarding the association between spontaneous CSF leaks and IIH, and the role of ICP in the pathophysiology of nontraumatic skull base defects. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000761DOI Listing
February 2019
1 Read

Long-term outcomes of cerebral venous sinus stenosis corrected by stenting

Curr Neurovasc Res 2019 02 6. Epub 2019 Feb 6.

Departments of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China

Background And Purpose: Cerebral venous sinus stenosis (CVSS) usually results in severe intracranial hypertension (IH), which can be corrected by stenting immediately. However, there is a lack of evidence of the long-term good outcomes in patients with CVSS who underwent stenting.

Methods: A total of 62 patients with imaging confirmed non-thrombotic and non-external compression CVSS were enrolled into this single center real-world cohort study after undergoing stenting, and were continuously followed up for more than 12 years. Read More

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http://dx.doi.org/10.2174/1567202616666190206185133DOI Listing
February 2019
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RE: "An Estimation of the Risk of Pseudotumor Cerebri Among Users of the Levonorgestrel Intrauterine Device".

Neuroophthalmology 2019 Feb 27;43(1):67-69. Epub 2018 Jul 27.

Pharmacovigilance, Medical Affairs & Pharmacovigilance, Pharmaceuticals, Bayer Oy, Espoo, Finland.

The current letter to the editor describes some of the limitations of Valenzuela et al.'s study on the association between levonorgestrel-releasing intrauterine system use and pseudotumor cerebri/idiopathic intracranial hypertension and further reinforces the authors' interpretations of the findings. Read More

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http://dx.doi.org/10.1080/01658107.2018.1465439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351020PMC
February 2019
1 Read

Idiopathic Intracranial Hypertension in a Mother and Pre-pubertal Twins.

Neuroophthalmology 2019 Feb 26;43(1):49-52. Epub 2018 Jun 26.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.

Idiopathic intracranial hypertension is a syndrome of elevated intracranial pressure without an identifiable cause. The majority of cases appear to be sporadic, and incidence is highest in obese women of childbearing age. The role of genetics in the pathophysiology of the disease is unclear, and familial cases are rare. Read More

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http://dx.doi.org/10.1080/01658107.2018.1480047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351011PMC
February 2019

Ganglion Cell Complex Analysis as a Potential Indicator of Early Neuronal Loss in Idiopathic Intracranial Hypertension.

Neuroophthalmology 2019 Feb 19;43(1):10-17. Epub 2018 Jun 19.

The New England Eye Center, Tufts Medical Center, Boston, Massachusetts, USA.

Reliable visual field testing is the gold standard in identifying future vision loss in patients with Idiopathic Intracranial hypertension (IIH). However, when field performance is unreliable, GCC analysis may be useful. We evaluated IIH patients over three visits: initial visit, follow-up visit and a third visit, almost 1 year later. Read More

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http://dx.doi.org/10.1080/01658107.2018.1476558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351016PMC
February 2019

Do Optic Canal Dimensions Measured on CT Influence the Degree of Papilloedema and Visual Dysfunction in Idiopathic Intracranial Hypertension?

Neuroophthalmology 2019 Feb 26;43(1):3-9. Epub 2018 Jun 26.

Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK.

A recent study found that increased optic canal area on magnetic resonance imaging was associated with worse papilloedema in idiopathic intracranial hypertension (IIH). We repeated this study using more accurate computerized tomography derived measurements. Optic canal dimensions were measured from 42 IIH patients and 24 controls. Read More

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http://dx.doi.org/10.1080/01658107.2018.1483406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351014PMC
February 2019
1 Read

Minocycline-induced transient depersonalization: A case report.

SAGE Open Med Case Rep 2019 17;7:2050313X18823827. Epub 2019 Jan 17.

Division of Dermatology, McGill University, Montreal, QC, Canada.

Minocycline is a medication commonly used for the treatment of acne vulgaris. The central nervous system-induced side effects of minocycline include headaches, pseudotumor cerebri, ataxia, and vestibular dysfunction. Many minocycline-related side effects have been presented in the literature, however, reports of depersonalization symptoms induced by the medication are rare. Read More

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http://dx.doi.org/10.1177/2050313X18823827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349971PMC
January 2019
1 Read

Pattern of Idiopathic Intracranial Hypertension in Indian Population.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):47-51

Department of Neuromedicine, Medical College, Kolkata, West Bengal, India.

Objective: To evaluate the clinical and demographic profile, laboratory parameters and outcomes of Idiopathic Intracranial hypertension (IIH) patients from Indian subpopulation.

Materials And Method: We did a prospective study on patients who fulfilled the revised diagnostic criteria for Primary pseudotumor cerebri syndrome in adults and children, proposed by Friedman et al in 2013. All patients were examined for BMI, papilloedema, extraocular muscle movement, opening CSF pressure and underwent MRI, MR venography of brain and perimetry. Read More

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http://dx.doi.org/10.4103/aian.AIAN_116_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327693PMC
January 2019

Contrast-Enhanced 3D-FLAIR Imaging of the Optic Nerve and Optic Nerve Head: Novel Neuroimaging Findings of Idiopathic Intracranial Hypertension.

AJNR Am J Neuroradiol 2019 Feb 24;40(2):334-339. Epub 2019 Jan 24.

From the Departments of Radiology (E.G., J.-P.J.Y., T.A.K.)

Background And Purpose: The sensitivity of contrast-enhanced 3D-FLAIR has not been assessed in patients with idiopathic intracranial hypertension. The purpose of this study was to evaluate whether hyperintensity of the optic nerve/optic nerve head on contrast-enhanced 3D-FLAIR imaging is associated with papilledema in patients with idiopathic intracranial hypertension.

Materials And Methods: A retrospective review was conducted from 2012 to 2015 of patients with clinically diagnosed idiopathic intracranial hypertension and age- and sex-matched controls who had MR imaging with contrast-enhanced 3D-FLAIR. Read More

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http://dx.doi.org/10.3174/ajnr.A5937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375763PMC
February 2019

Diagnosis and Management of Cerebral Venous Diseases in Neuro-Ophthalmology: Ongoing Controversies.

Asia Pac J Ophthalmol (Phila) 2019 Jan 23. Epub 2019 Jan 23.

Department of Ophthalmology, Weill Cornell Medical College, New York, United States.

Diseases of the cerebral venous system frequently lead to neuro-ophthalmic complications. Cortical venous sinus thrombosis and dural arteriovenous fistulas may be complicated by elevation of intracranial pressure, with secondary papilledema or abducens palsies. There is increasing recognition that stenosis at the transverse sinus-sigmoid sinus junction plays a role in the pathophysiology of idiopathic intracranial hypertension and offers a new avenue of treatment in patients who fail medical therapy. Read More

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http://dx.doi.org/10.22608/APO.2018239DOI Listing
January 2019
2 Reads

Isolated spontaneous cerebrospinal fluid rhinorrhoea as a rare presentation of idiopathic intracranial hypertension: Case reports with comprehensive review of literature.

Indian J Radiol Imaging 2018 Oct-Dec;28(4):406-411

Department of Radiology, Yale New Haven Health Bridgeport Hospital, Bridgeport, CT, USA.

Isolated cerebrospinal fluid (CSF) rhinorrhoea as a sole presenting symptom of idiopathic intracranial hypertension (IIH) is extremely rare. IIH typically presents with headache, pulsatile tinnitus, dizziness, nausea, vomiting, and visual disturbance. We report two cases which presented with acute onset spontaneous CSF rhinorrhoea without any other symptom. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_228_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319102PMC
January 2019
1 Read

Ventriculo-peritoneal shunting is a safe and effective treatment for idiopathic intracranial hypertension.

Br J Neurosurg 2019 Jan 17:1-9. Epub 2019 Jan 17.

a Department of Neurosurgery , Cambridge University Hospitals NHS Foundation Trust , Cambridge , UK.

Purpose: To determine the outcome of ventriculo-peritoneal shunts as a treatment for idiopathic intracranial hypertension (IIH) Materials and Methods: Retrospective case series of 28 patients with IIH and evidence of raised intracranial pressure (ICP) who underwent shunt insertion. Patients were identified from a prospectively updated operative database. A case-notes review was performed and data on type of shunt, pre- and post-operative symptoms, ophthalmological findings and post-operative complications were recorded. Read More

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http://dx.doi.org/10.1080/02688697.2018.1538478DOI Listing
January 2019
2 Reads

The Effect of Acetazolamide and Weight Loss on Intraocular Pressure in Idiopathic Intracranial Hypertension Patients.

J Glaucoma 2019 Jan 7. Epub 2019 Jan 7.

*Neuro-Ophthalmology, New York Eye and Ear Infirmary and Icahn School of Medicine at Mount Sinai, New York, New York †Dept. of Electrical and Computer Engineering, The University of Iowa, Iowa City, IA ‡Iowa City VA Health Care System and Iowa City VA Center for the Prevention and Treatment of Visual Loss, Iowa City, IA.

Purpose: Acetazolamide (ACZ) lowers IOP, acutely in normal eyes and both acutely and chronically in eyes with glaucoma, and cerebrospinal fluid pressure (CSFp), chronically in patients with idiopathic intracranial hypertension (IIH). We hypothesize chronic daily ACZ would significantly reduce IOP and contribute to a translaminar pressure gradient change reflected by alteration in the CSFp-IOP difference and the deformation of the neural canal in patients with IIH and no glaucoma.

Methods And Patients: Prior to randomization to ACZ or placebo treatment for six months, 165 participants in the IIH Treatment Trial had evaluations that included Goldmann applanation, CSFp measurement, and OCT determination of the neural canal deformation. Read More

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http://Insights.ovid.com/crossref?an=00061198-900000000-9823
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http://dx.doi.org/10.1097/IJG.0000000000001189DOI Listing
January 2019
1 Read
2.427 Impact Factor

Association Between Peripapillary Bruch's Membrane Shape and Intracranial Pressure: Effect of Image Acquisition Pattern and Image Analysis Method, a Preliminary Study.

Front Neurol 2018 21;9:1137. Epub 2018 Dec 21.

Department of Ophthalmology, Stanford University, Palo Alto, CA, United States.

High intracranial pressure (ICP) is associated with changes in peripapillary Bruch's membrane (pBM) shape on optical coherence tomography (OCT) images of the optic nerve head. It is not known if image acquisition pattern and analysis method impact this association. Cross sectional OCT scans of the optic nerve head were obtained at six angles using a radial scan pattern in 21 subjects immediately prior to ICP measurement via lumbar puncture. Read More

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http://dx.doi.org/10.3389/fneur.2018.01137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308322PMC
December 2018

Sulcal FLAIR hyperintensity after CSF removal in two patients with intracranial hypertension.

Eur J Radiol Open 2019 24;6:33-35. Epub 2018 Dec 24.

Department of Radiology and Radiologic Sciences, Neuroradiology, Medical University of South Carolina, Charleston, SC, United States.

Sulcal hyperintensity on fluid-attenuated inversion recovery (FLAIR) sequence is a frequently encountered finding that could be due to an abnormality of cerebrospinal fluid, a secondary finding related to an intracranial pathologic process, or be artifactual or iatrogenic. Here we present two cases of sulcal FLAIR hyperintensity in the setting of intracranial hypotension after CSF removal for intracranial hypertension. Read More

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http://dx.doi.org/10.1016/j.ejro.2018.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308253PMC
December 2018
1 Read

Adolescent with unilateral vision loss.

Arch Dis Child Educ Pract Ed 2019 Jan 7. Epub 2019 Jan 7.

Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

QUESTION 1: What is the most likely diagnosis?Optical neuritis (ON).Central nervous system (CNS) tumour.Functional visual loss (FVL). Read More

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http://dx.doi.org/10.1136/archdischild-2018-316153DOI Listing
January 2019
2 Reads

PARACENTRAL ACUTE MIDDLE MACULOPATHY ASSOCIATED WITH IDIOPATHIC INTRACRANIAL HYPERTENSION.

Retin Cases Brief Rep 2019 Jan 3. Epub 2019 Jan 3.

Department of Ophthalmology, California Pacific Medical Center, San Francisco, California.

Purpose: Paracentral acute middle maculopathy (PAMM) is a recently identified clinical entity with numerous retinal vascular and systemic associations. To our knowledge, this is the first reported case of PAMM associated with idiopathic intracranial hypertension.

Methods: A case is presented with multimodal imaging. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000846DOI Listing
January 2019

Pseudotumour cerebri associated with mycoplasma pneumoniae infection and treatment with levofloxacin: a case report.

BMC Pediatr 2019 Jan 5;19(1). Epub 2019 Jan 5.

Pediatric Highly Intensive Care Unit, Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, and a Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Background: Idiopathic intracranial hypertension (IIH), also known as pseudotumour cerebri syndrome (PTCS), is characterized by the presence of signs and symptoms of raised intracranial pressure without evidence of any intracranial structural cause and with normal cerebrospinal fluid microscopy and biochemistry. Obesity, various systemic diseases and endocrine conditions, and a number of medications are known to be risk factors for PTCS. The medications commonly associated with PTCS are amiodarone, antibiotics, corticosteroids, cyclosporine, growth hormone, oral contraceptives, vitamin A analogues, lithium, phenytoin, NSAIDs, leuprolide acetate, and some neuroleptic drugs. Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-018-1371-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320575PMC
January 2019
3 Reads

Optimization of 3D phase contrast venography for the assessment of the cranio-cervical venous system at 1.5 T.

Neuroradiology 2019 Jan 4. Epub 2019 Jan 4.

Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department for Radiology and Neuroradiology, University Medical Center, Arnold Heller Street 3, Building 41, 24105, Kiel, Germany.

Purpose: The aim of this work was to optimize a three-dimensional (3D) phase-contrast venography (PCV) product MR pulse sequence in order to obtain clinically reliable images with less artifacts for an improved depiction of the cranio-cervical venous vessels.

Methods: Starting from the product sequence, the 3D PCV protocol was optimized in eight steps with respect to the velocity encoding (V) direction and value, slice thickness, reduction of susceptibility artifacts and arterial contamination, gradient mode and radio-frequency (RF)-spoiling, B-Shimming, asymmetric echo technique and RF-pulse type, and flip angle. The product and optimized protocol was used to perform 3D PCV in 12 healthy male volunteers with a median age of 50 years using a state-of-the-art 1. Read More

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http://dx.doi.org/10.1007/s00234-018-2146-6DOI Listing
January 2019
2 Reads

Peripapillary Vessel Density Measured by Optical Coherence Tomography Angiography in Idiopathic Intracranial Hypertension.

J Neuroophthalmol 2018 Dec 31. Epub 2018 Dec 31.

Ophthalmology Department, Ankara University Faculty of Medicine, Ankara, Turkey.

Background: Although alterations in the peripapillary retinal nerve fiber layer (RNFL) in patients with idiopathic intracranial hypertension (IIH) have been characterized using optical coherence tomography (OCT), there are little data regarding the peripapillary vasculature in this patient population. Our aim was to evaluate findings of OCT angiography (OCT-A) in the peripapillary region in addition to the RNFL measurements on OCT in patients with IIH.

Methods: Thirty-eight eyes of 19 patients with IIH and 42 eyes of 21 healthy controls were enrolled in our study. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000745DOI Listing
December 2018
4 Reads

Femoral-Long Sheath-Reshape-Anchoring-Stenting (FLRAS) Technique in Venous Sinus Stenting for Idiopathic Intracranial Hypertension.

World Neurosurg 2018 Dec 24. Epub 2018 Dec 24.

West China Hospital, Sichuan University, Guoxuexiang 37, Chengdu, 611137, China. Electronic address:

Objective: To evaluate the efficacy and safety of the novel Femoral-Long Sheath-Reshape-Anchoring-Stenting (FLRAS) technique (developed by Dr. Hongbo Zheng) for venous sinus stenting in patients with idiopathic intracranial hypertension.

Design: Retrospective, single center study. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.052DOI Listing
December 2018

Optical coherence tomography represents a sensitive and reliable tool for routine monitoring of idiopathic intracranial hypertension with and without papilledema.

Eur J Neurol 2018 Dec 26. Epub 2018 Dec 26.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.

Background And Purpose: We previously reported that certain optical coherence tomography (OCT) measures were sensitive and reliable in identifying idiopathic intracranial hypertension (IIH). This prospective study aimed to define OCT measures that allow differentiation of IIH with and without papilledema, thereby helping clinical decision-making.

Methods: Eight patients with IIH with papilledema, nine without papilledema and 19 with other neurological diseases were included. Read More

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http://dx.doi.org/10.1111/ene.13893DOI Listing
December 2018
2 Reads

Melanopsin Retinal Ganglion Cells and Pupil: Clinical Implications for Neuro-Ophthalmology.

Front Neurol 2018 7;9:1047. Epub 2018 Dec 7.

Unità Operativa Complessa Clinica Neurologica, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Bellaria, Bologna, Italy.

Melanopsin retinal ganglion cells (mRGCs) are intrinsically photosensitive RGCs that mediate many relevant non-image forming functions of the eye, including the pupillary light reflex, through the projections to the olivary pretectal nucleus. In particular, the post-illumination pupil response (PIPR), as evaluated by chromatic pupillometry, can be used as a reliable marker of mRGC function . In the last years, pupillometry has become a promising tool to assess mRGC dysfunction in various neurological and neuro-ophthalmological conditions. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2018.01047
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http://dx.doi.org/10.3389/fneur.2018.01047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292931PMC
December 2018
3 Reads

The link between idiopathic intracranial hypertension, fibromyalgia, and chronic fatigue syndrome: exploration of a shared pathophysiology.

J Pain Res 2018 10;11:3129-3140. Epub 2018 Dec 10.

Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Musculoskeletal Rehabilitation Research Unit, University of Leuven, Leuven, Belgium,

Purpose: Idiopathic intracranial hypertension (IICH) is a condition characterized by raised intracranial pressure (ICP), and its diagnosis is established when the opening pressure measured during a lumbar puncture is elevated >20 cm HO in nonobese patients or >25 cm HO in obese patients. Papilledema is caused by forced filling of the optic nerve sheath with cerebrospinal fluid (CSF). Other common but underappreciated symptoms of IICH are neck pain, back pain, and radicular pain in the arms and legs resulting from associated increased spinal pressure and forced filling of the spinal nerves with CSF. Read More

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https://www.dovepress.com/the-link-between-idiopathic-intrac
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http://dx.doi.org/10.2147/JPR.S186878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292399PMC
December 2018
9 Reads

Predictors of Primary Intracranial Hypertension in Children Using a Newly Suggested Opening Pressure Cutoff of 280 mm HO.

Pediatr Neurol 2019 Feb 19;91:27-33. Epub 2018 Oct 19.

Department of Emergency Medicine, Department of Informatics, Boston Children's Hospital, Boston, Massachusetts. Electronic address:

Objectives: We assessed the clinical characteristics of primary intracranial hypertension (PIH) in children using a newly recommended threshold for cerebrospinal fluid opening pressure (280 mm HO).

Method: Cross-sectional study of patients age ≤21 years who had a lumbar puncture done for evaluation of PIH. Patients were excluded if lumbar puncture was done for a suspected infection, seizure, mental status changes, multiple sclerosis, or Guillain-Barre syndrome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183071
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http://dx.doi.org/10.1016/j.pediatrneurol.2018.09.013DOI Listing
February 2019
8 Reads

Pseudotumor cerebri in childhood and adolescence: data from a specialized service.

Arq Neuropsiquiatr 2018 Nov;76(11):751-755

Universidade Federal de São Paulo, Departamento de Pediatria, Unidade de Reumatologia Pediátrica, São Paulo SP, Brasil.

Objective: To report cases of children and adolescents diagnosed with pseudotumor cerebri associated or not with rheumatic disease.

Methods: This was a retrospective study based on medical reports of 29 patients, up to 18 years of age and diagnosed with pseudotumor cerebri, followed up in the Pediatric Rheumatology and Neurology outpatient clinics of a tertiary hospital, until December 2016.

Results: Among the 29 patients diagnosed with pseudotumor cerebri, 51. Read More

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http://dx.doi.org/10.1590/0004-282X20180131DOI Listing
November 2018
4 Reads

Idiopathic intracranial hypertension in the British population with obesity.

Acta Neurochir (Wien) 2019 Feb 18;161(2):239-246. Epub 2018 Dec 18.

Academic Unit, Department of Surgery and Cancer, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

Purpose: Idiopathic intracranial hypertension (IIH) is a syndrome that is characterized by persistently high intracranial pressure and associated with high rates of morbidity and visual loss. Its exact etiology and clinical picture is poorly understood, but it is known to be associated with obesity. The aim of this study was to investigate the prevalence and clinical manifestations of IIH using a large nationwide database of British subjects. Read More

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http://dx.doi.org/10.1007/s00701-018-3772-9DOI Listing
February 2019
11 Reads

Evaluation of CSF flow metrics in patients with communicating hydrocephalus and idiopathic intracranial hypertension.

Radiol Med 2018 Dec 17. Epub 2018 Dec 17.

Department of Radiology, BezmialemVakif University, Istanbul, Turkey.

Purpose: To search for CSF dynamics of idiopathic intracranial hypertension (IIH) and communicating hydrocephalus and any correlation between MRI findings, CSF metrics and CSF opening pressure in IIH.

Materials And Methods: Healthy subjects (30) and subjects with IIH (29) and high-pressure communicating hydrocephalus (43) were enrolled. Nonparametric Kruskal-Wallis test (p = 0. Read More

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http://link.springer.com/10.1007/s11547-018-0979-z
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http://dx.doi.org/10.1007/s11547-018-0979-zDOI Listing
December 2018
5 Reads
1.368 Impact Factor

Advances in the understanding of headache in idiopathic intracranial hypertension.

Curr Opin Neurol 2019 Feb;32(1):92-98

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston.

Purpose Of Review: To review the most relevant developments in the understanding of headache in idiopathic intracranial hypertension (IIH).

Recent Findings: The phenotype of the typical IIH headache is diverging from the historical thinking of a raised intracranial pressure headache, with the majority being classified as having migraine. A larger proportion of those with IIH have a past medical history of migraine, compared with the general population, highlighting the importance of re-examining those who have a change or escalation in their headache. Read More

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http://Insights.ovid.com/crossref?an=00019052-900000000-9906
Publisher Site
http://dx.doi.org/10.1097/WCO.0000000000000651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343949PMC
February 2019
16 Reads

Mesalazine treatment causing resolution of intracranial hypertension secondary to ulcerative colitis: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13365

Department of Ophthalmology, Fondation Ophtalmologique Adolphe de Rothschild.

Rationale: The association between intracranial hypertension (ICH) and ulcerative colitis (UC) is rare. We report the unusual case of a male patient with UC and ICH in whom both conditions resolved with mesalazine therapy.

Patient Concerns: A 48-year-old Caucasian man presented to our department in June 2016 for decreased vision, transient visual obscuration, pulsatile tinnitus and headaches of 7 months duration. Read More

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http://dx.doi.org/10.1097/MD.0000000000013365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310519PMC
December 2018
3 Reads

Cerebral Venous Thrombosis: An Uncommon Cause of Papilledema on Bedside Ocular Ultrasound.

J Emerg Med 2018 Dec 8. Epub 2018 Dec 8.

Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, Florida.

Background: Cerebral venous thrombosis (CVT) is a rare, difficult-to-diagnose form of venous thromboembolic disease and is considered a type of stroke. Its presentation is highly variable and may be easily confused for more common and less debilitating or life-threatening diagnoses such as migraine, seizure, or idiopathic intracranial hypertension.

Case Report: A 25-year-old woman presented with a complaint of bifrontal throbbing headache and blurry vision. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.10.036DOI Listing
December 2018
1 Read

Short-term Optic Disc Cupping Reversal in a Patient with Mild Juvenile Open-angle Glaucoma Due to Early Idiopathic Intracranial Hypertension.

J Glaucoma 2018 Dec 10. Epub 2018 Dec 10.

Vanderbilt Eye Institute, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232.

Purpose: The purpose of this study is to report a case of optic disc cupping reversal in an adult without significant intraocular pressure lowering treatment.

Patient: A 20-year-old female with a history of mild juvenile open-angle glaucoma who developed subjective blurred vision and a decrease in cupping of her optic discs.

Results: Dilated examination demonstrated decreased cup-to-disc ratios in both eyes with slight blurring of the disc margin in the right eye. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001151DOI Listing
December 2018

Optic nerve appearance as a predictor of visual outcome in patients with idiopathic intracranial hypertension.

Br J Ophthalmol 2018 Dec 8. Epub 2018 Dec 8.

Department of Ophthalmology, Emory University, Atlanta, Georgia, USA

Background/aims: It remains unclear whether the presence of optic disc haemorrhages (ODH) or cotton wool spots (CWS) at presentation in patients with papilloedema from idiopathic intracranial hypertension (IIH) has prognostic value. The aim of this study was to determine if optic disc appearance at presentation predicts visual outcome in patients with IIH.

Methods: Retrospective study of 708 eyes of 360 consecutive patients with IIH who had baseline optic disc photographs before or within 30 days of their diagnostic lumbar puncture and initiation of medical treatment. Read More

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3133
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http://dx.doi.org/10.1136/bjophthalmol-2018-313329DOI Listing
December 2018
4 Reads

Management of sphenoid lateral recess encephalocoeles.

Curr Opin Otolaryngol Head Neck Surg 2019 Feb;27(1):37-46

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Purpose Of Review: Sphenoid sinus lateral recess encephalocoeles (SSLRE) are rare occurrences and pose unique challenges due to limited surgical access for endoscopic endonasal repair and also the lack of consensus on optimal perioperative managements specifically in the spontaneous cases, which are also believed to be a variant of idiopathic intracranial hypertension (IIH). Endoscopic endonasal approaches have largely replaced the transcranial route and the techniques are continuously being refined to reduce the neurovascular morbidity and improve outcome.

Recent Findings: Transpetrygoid is the most utilized approach with modifications suggested to limit bone removal, exposure and preservation of the neurovascular structures as dictated by the extent of the lateral recess. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000508DOI Listing
February 2019
2 Reads

Herpes simplex encephalitis and pseudotumour cerebri due to ısotretinoin.

J Pak Med Assoc 2018 Dec;68(12):1833-11835

Department of Internal Medicine, Medical School, Firat University, Elazig Turkey.

Isotretinoin can have significant adverse reactions on multiple systems. We report a unique case of pseudotumour cerebri and herpes encephalitis resulting due to isotretinoin. A 19-year-old female patient was admitted to our clinic, presenting with headache, nausea, vomiting and fever since three days. Read More

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December 2018
12 Reads

Pseudotumor Cerebri Syndrome is the Best Term for This Condition.

Pediatr Neurol 2018 Oct 16;87:9-10. Epub 2018 Aug 16.

Departments of Neurology and Ophthalmology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Division of Ophthalmology, Neuro-ophthalmology Service, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183087
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http://dx.doi.org/10.1016/j.pediatrneurol.2018.08.018DOI Listing
October 2018
6 Reads

Eliminating the Secret Handshake: A Plea for Clarity in Medical Terminology.

Authors:
E Steve Roach

Pediatr Neurol 2018 Oct 16;87:7-8. Epub 2018 Aug 16.

The University of Texas Dell Medical School, Austin, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2018.08.019DOI Listing
October 2018
1 Read

Diagnostic error and neuro-ophthalmology.

Curr Opin Neurol 2019 Feb;32(1):62-67

Department of Ophthalmology.

Purpose Of Review: This review summarizes the recent literature on diagnostic error relevant to the practice of neuro-ophthalmology, and evaluates the potential for increased access to neuro-ophthalmology to decrease rates of diagnostic error, thereby reducing medical harm and spending on unnecessary tests and treatments.

Recent Findings: Despite medical advances, current research continues to show alarmingly high rates of diagnostic error. Research into diagnostic error shows that many of these errors can be traced to cognitive errors. Read More

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http://Insights.ovid.com/crossref?an=00019052-900000000-9906
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http://dx.doi.org/10.1097/WCO.0000000000000635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310060PMC
February 2019
10 Reads

Suprasellar Epidermoid Cyst Originating from the Infundibulum: Case Report and Literature Review.

Cureus 2018 Aug 29;10(8):e3226. Epub 2018 Aug 29.

Neurological Surgery, George Washington University, Washington DC, USA.

Epidermoid cysts account for a small fraction of intracranial brain tumors, most commonly found in the cerebellopontine angle and parasellar cisterns. Here we present a rare case of an epidermoid cyst located in the suprasellar region, specifically originating from the infundibulum. Only one additional case with an epidermoid cyst originating within the pituitary stalk has been previously reported in the literature. Read More

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http://dx.doi.org/10.7759/cureus.3226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263494PMC
August 2018
1 Read

Intracranial hypertension after Chiari decompression resolving after removal of a levonorgestrel-releasing intrauterine device: case report.

J Neurosurg 2018 Oct 1:1-4. Epub 2018 Oct 1.

Levonorgestrel-releasing intrauterine devices (LIUDs) are thought to release this progestin locally in the uterus to limit side effects. Authors here present a case of treatment-refractory hydrocephalus and pseudomeningocele (PMC), both of which fully resolved after LIUD removal.A 35-year-old woman with an implanted LIUD developed symptomatic PMC and hydrocephalus after suboccipital craniectomy for Chiari malformation type I. Read More

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http://dx.doi.org/10.3171/2018.5.JNS18315DOI Listing
October 2018
1 Read

Diffusion tensor imaging of the optic disc in idiopathic intracranial hypertension?

Authors:
Halil Onder

Neuroradiology 2019 Jan 28;61(1):17-18. Epub 2018 Nov 28.

Neurology Clinic, Yozgat City Hospital, Yozgat, Turkey.

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http://dx.doi.org/10.1007/s00234-018-2144-8DOI Listing
January 2019
1 Read

Cerebro-venous hypertension: a frequent cause of so-called "external hydrocephalus" in infants.

Childs Nerv Syst 2019 Feb 24;35(2):251-256. Epub 2018 Nov 24.

Division of Pediatric Neurosurgery, Department of Neurosurgery, University Hospital of Tuebingen, Tuebingen, Germany.

Introduction: External hydrocephalus (eHC) is commonly defined as a subtype of infant "hydrocephalus" consisting of macrocepahly associated with enlarged subarachnoid space and no or mild ventriculomegaly. This status is thought to be related to impaired CSF absorption because of arachnoid villi immaturity. However, other factors like the venous system might be involved in the development of the clinical picture. Read More

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http://link.springer.com/10.1007/s00381-018-4007-3
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http://dx.doi.org/10.1007/s00381-018-4007-3DOI Listing
February 2019
8 Reads

Non-Syndromic Craniosynostosis Mimicking Primary Pseudotumor Cerebri Syndrome.

Headache 2019 Feb 25;59(2):264-265. Epub 2018 Nov 25.

Department of Pediatric Neurology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/head.13450DOI Listing
February 2019
1 Read

Neuro-Ophthalmic Disorders in Pregnancy.

Neurol Clin 2019 Feb;37(1):85-102

Department of Neurology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Department of Ophthalmology, Massachusetts Eye and Ear, 243 Charles Street, Boston, MA 02114, USA. Electronic address:

The physiologic changes that accompany pregnancy can have important implications for neuro-ophthalmic disease. This article discusses pregnancy-related considerations for meningioma, pituitary disorders, demyelinating disease, myasthenia gravis, thyroid eye disease, idiopathic intracranial hypertension, cerebral venous sinus thrombosis, stroke, migraine, and cranial neuropathies. The article also details the potential neuro-ophthalmic complications of preeclampsia and eclampsia and reviews the use of common diagnostic studies during pregnancy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338619183125
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http://dx.doi.org/10.1016/j.ncl.2018.09.001DOI Listing
February 2019
10 Reads