4,652 results match your criteria Idiopathic Intracranial Hypertension


Advances in the understanding of headache in idiopathic intracranial hypertension.

Curr Opin Neurol 2019 Feb;32(1):92-98

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston.

Purpose Of Review: To review the most relevant developments in the understanding of headache in idiopathic intracranial hypertension (IIH).

Recent Findings: The phenotype of the typical IIH headache is diverging from the historical thinking of a raised intracranial pressure headache, with the majority being classified as having migraine. A larger proportion of those with IIH have a past medical history of migraine, compared with the general population, highlighting the importance of re-examining those who have a change or escalation in their headache. Read More

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http://Insights.ovid.com/crossref?an=00019052-900000000-9906
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http://dx.doi.org/10.1097/WCO.0000000000000651DOI Listing
February 2019
2 Reads

Mesalazine treatment causing resolution of intracranial hypertension secondary to ulcerative colitis: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13365

Department of Ophthalmology, Fondation Ophtalmologique Adolphe de Rothschild.

Rationale: The association between intracranial hypertension (ICH) and ulcerative colitis (UC) is rare. We report the unusual case of a male patient with UC and ICH in whom both conditions resolved with mesalazine therapy.

Patient Concerns: A 48-year-old Caucasian man presented to our department in June 2016 for decreased vision, transient visual obscuration, pulsatile tinnitus and headaches of 7 months duration. Read More

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http://dx.doi.org/10.1097/MD.0000000000013365DOI Listing
December 2018

Cerebral Venous Thrombosis: An Uncommon Cause of Papilledema on Bedside Ocular Ultrasound.

J Emerg Med 2018 Dec 8. Epub 2018 Dec 8.

Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, Florida.

Background: Cerebral venous thrombosis (CVT) is a rare, difficult-to-diagnose form of venous thromboembolic disease and is considered a type of stroke. Its presentation is highly variable and may be easily confused for more common and less debilitating or life-threatening diagnoses such as migraine, seizure, or idiopathic intracranial hypertension.

Case Report: A 25-year-old woman presented with a complaint of bifrontal throbbing headache and blurry vision. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.10.036DOI Listing
December 2018

Short-term Optic Disc Cupping Reversal in a Patient with Mild Juvenile Open-angle Glaucoma Due to Early Idiopathic Intracranial Hypertension.

J Glaucoma 2018 Dec 10. Epub 2018 Dec 10.

Vanderbilt Eye Institute, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232.

Purpose: The purpose of this study is to report a case of optic disc cupping reversal in an adult without significant intraocular pressure lowering treatment.

Patient: A 20-year-old female with a history of mild juvenile open-angle glaucoma who developed subjective blurred vision and a decrease in cupping of her optic discs.

Results: Dilated examination demonstrated decreased cup-to-disc ratios in both eyes with slight blurring of the disc margin in the right eye. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001151DOI Listing
December 2018

Optic nerve appearance as a predictor of visual outcome in patients with idiopathic intracranial hypertension.

Br J Ophthalmol 2018 Dec 8. Epub 2018 Dec 8.

Department of Ophthalmology, Emory University, Atlanta, Georgia, USA

Background/aims: It remains unclear whether the presence of optic disc haemorrhages (ODH) or cotton wool spots (CWS) at presentation in patients with papilloedema from idiopathic intracranial hypertension (IIH) has prognostic value. The aim of this study was to determine if optic disc appearance at presentation predicts visual outcome in patients with IIH.

Methods: Retrospective study of 708 eyes of 360 consecutive patients with IIH who had baseline optic disc photographs before or within 30 days of their diagnostic lumbar puncture and initiation of medical treatment. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2018-313329DOI Listing
December 2018

Management of sphenoid lateral recess encephalocoeles.

Curr Opin Otolaryngol Head Neck Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Purpose Of Review: Sphenoid sinus lateral recess encephalocoeles (SSLRE) are rare occurrences and pose unique challenges due to limited surgical access for endoscopic endonasal repair and also the lack of consensus on optimal perioperative managements specifically in the spontaneous cases, which are also believed to be a variant of idiopathic intracranial hypertension (IIH). Endoscopic endonasal approaches have largely replaced the transcranial route and the techniques are continuously being refined to reduce the neurovascular morbidity and improve outcome.

Recent Findings: Transpetrygoid is the most utilized approach with modifications suggested to limit bone removal, exposure and preservation of the neurovascular structures as dictated by the extent of the lateral recess. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000508DOI Listing
November 2018
1 Read

Herpes simplex encephalitis and pseudotumour cerebri due to ısotretinoin.

J Pak Med Assoc 2018 Dec;68(12):1833-11835

Department of Internal Medicine, Medical School, Firat University, Elazig Turkey.

Isotretinoin can have significant adverse reactions on multiple systems. We report a unique case of pseudotumour cerebri and herpes encephalitis resulting due to isotretinoin. A 19-year-old female patient was admitted to our clinic, presenting with headache, nausea, vomiting and fever since three days. Read More

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December 2018
8 Reads

Pseudotumor Cerebri Syndrome is the Best Term for This Condition.

Pediatr Neurol 2018 Oct 16;87:9-10. Epub 2018 Aug 16.

Departments of Neurology and Ophthalmology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Division of Ophthalmology, Neuro-ophthalmology Service, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2018.08.018DOI Listing
October 2018

Eliminating the Secret Handshake: A Plea for Clarity in Medical Terminology.

Authors:
E Steve Roach

Pediatr Neurol 2018 Oct 16;87:7-8. Epub 2018 Aug 16.

The University of Texas Dell Medical School, Austin, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2018.08.019DOI Listing
October 2018

Diagnostic error and neuro-ophthalmology.

Curr Opin Neurol 2019 Feb;32(1):62-67

Department of Ophthalmology.

Purpose Of Review: This review summarizes the recent literature on diagnostic error relevant to the practice of neuro-ophthalmology, and evaluates the potential for increased access to neuro-ophthalmology to decrease rates of diagnostic error, thereby reducing medical harm and spending on unnecessary tests and treatments.

Recent Findings: Despite medical advances, current research continues to show alarmingly high rates of diagnostic error. Research into diagnostic error shows that many of these errors can be traced to cognitive errors. Read More

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http://Insights.ovid.com/crossref?an=00019052-900000000-9906
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http://dx.doi.org/10.1097/WCO.0000000000000635DOI Listing
February 2019
4 Reads

Suprasellar Epidermoid Cyst Originating from the Infundibulum: Case Report and Literature Review.

Cureus 2018 Aug 29;10(8):e3226. Epub 2018 Aug 29.

Neurological Surgery, George Washington University, Washington DC, USA.

Epidermoid cysts account for a small fraction of intracranial brain tumors, most commonly found in the cerebellopontine angle and parasellar cisterns. Here we present a rare case of an epidermoid cyst located in the suprasellar region, specifically originating from the infundibulum. Only one additional case with an epidermoid cyst originating within the pituitary stalk has been previously reported in the literature. Read More

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http://dx.doi.org/10.7759/cureus.3226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263494PMC
August 2018
1 Read

Intracranial hypertension after Chiari decompression resolving after removal of a levonorgestrel-releasing intrauterine device: case report.

Authors:

J Neurosurg 2018 Oct 1:1-4. Epub 2018 Oct 1.

Levonorgestrel-releasing intrauterine devices (LIUDs) are thought to release this progestin locally in the uterus to limit side effects. Authors here present a case of treatment-refractory hydrocephalus and pseudomeningocele (PMC), both of which fully resolved after LIUD removal.A 35-year-old woman with an implanted LIUD developed symptomatic PMC and hydrocephalus after suboccipital craniectomy for Chiari malformation type I. Read More

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http://dx.doi.org/10.3171/2018.5.JNS18315DOI Listing
October 2018
1 Read

Diffusion tensor imaging of the optic disc in idiopathic intracranial hypertension?

Authors:
Halil Onder

Neuroradiology 2018 Nov 28. Epub 2018 Nov 28.

Neurology Clinic, Yozgat City Hospital, Yozgat, Turkey.

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http://dx.doi.org/10.1007/s00234-018-2144-8DOI Listing
November 2018
1 Read

Cerebro-venous hypertension: a frequent cause of so-called "external hydrocephalus" in infants.

Childs Nerv Syst 2018 Nov 24. Epub 2018 Nov 24.

Division of Pediatric Neurosurgery, Department of Neurosurgery, University Hospital of Tuebingen, Tuebingen, Germany.

Introduction: External hydrocephalus (eHC) is commonly defined as a subtype of infant "hydrocephalus" consisting of macrocepahly associated with enlarged subarachnoid space and no or mild ventriculomegaly. This status is thought to be related to impaired CSF absorption because of arachnoid villi immaturity. However, other factors like the venous system might be involved in the development of the clinical picture. Read More

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http://link.springer.com/10.1007/s00381-018-4007-3
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http://dx.doi.org/10.1007/s00381-018-4007-3DOI Listing
November 2018
5 Reads

Non-Syndromic Craniosynostosis Mimicking Primary Pseudotumor Cerebri Syndrome.

Headache 2018 Nov 25. Epub 2018 Nov 25.

Department of Pediatric Neurology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/head.13450DOI Listing
November 2018
1 Read

Neuro-Ophthalmic Disorders in Pregnancy.

Neurol Clin 2019 Feb;37(1):85-102

Department of Neurology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Department of Ophthalmology, Massachusetts Eye and Ear, 243 Charles Street, Boston, MA 02114, USA. Electronic address:

The physiologic changes that accompany pregnancy can have important implications for neuro-ophthalmic disease. This article discusses pregnancy-related considerations for meningioma, pituitary disorders, demyelinating disease, myasthenia gravis, thyroid eye disease, idiopathic intracranial hypertension, cerebral venous sinus thrombosis, stroke, migraine, and cranial neuropathies. The article also details the potential neuro-ophthalmic complications of preeclampsia and eclampsia and reviews the use of common diagnostic studies during pregnancy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338619183125
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http://dx.doi.org/10.1016/j.ncl.2018.09.001DOI Listing
February 2019
4 Reads

Differences in the Calculated Transvenous Pressure Drop between Chronic Hydrocephalus and Idiopathic Intracranial Hypertension.

AJNR Am J Neuroradiol 2018 Nov 22. Epub 2018 Nov 22.

Biomedical Engineering (A.R.B.), University of New South Wales, Sydney, New South Wales, Australia.

Background And Purpose: Chronic hydrocephalus is associated with dilated ventricles despite a normal intracranial pressure. In idiopathic intracranial hypertension, the ventricles are normal despite an elevated intracranial pressure. This apparent paradox has largely remained unexplained. Read More

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http://dx.doi.org/10.3174/ajnr.A5883DOI Listing
November 2018

Imaging of Tinnitus.

Neuroimaging Clin N Am 2019 Feb 31;29(1):49-56. Epub 2018 Oct 31.

Department of Radiology, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA. Electronic address:

Although not all patients with tinnitus require imaging, patients with tinnitus and asymmetric hearing loss, additional neurologic findings, or pulsatile tinnitus should be evaluated with an appropriately tailored imaging study. Choice of imaging study should be guided by type of hearing loss and additional physical examination findings, such as middle ear lesion, presence of carotid bruit, or pulsatile tinnitus extinguished by jugular compression. Read More

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http://dx.doi.org/10.1016/j.nic.2018.09.006DOI Listing
February 2019
3 Reads

Transcranial Color-Coded Sonography for Monitoring Idiopathic Intracranial Hypertension.

Ultraschall Med 2018 Nov 20. Epub 2018 Nov 20.

Neurology, Madonna-del-Soccorso-Hospital, San Benedetto del Tronto (AP), Italy.

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http://dx.doi.org/10.1055/a-0783-2541DOI Listing
November 2018

Skull Base Dural Thickness and Relationship to Demographic Features: A Postmortem Study and Literature Review.

J Neurol Surg B Skull Base 2018 Dec 5;79(6):614-620. Epub 2018 Jun 5.

Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States.

Dural membrane is an important anatomic structure that surrounds and protects the entire central nervous system. Physical properties of the dura have many pathophysiological and therapeutic implications in cranial surgery, especially skull base disorders. The aim of this study is to investigate variation in skull base dural thickness and correlation with different demographic parameters. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1651501
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http://dx.doi.org/10.1055/s-0038-1651501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239876PMC
December 2018
4 Reads

[Clinical evaluation of vocal fold paralysis in 207 children].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Nov;53(11):847-850

Department of Otorhinolaryngology Head and Neck Surgery, Children's Hospital of Fudan University, Shanghai 201102, China.

To investigate the etiology and clinical characteristics of vocal fold paralysis in children. To provide useful information for diagnosis, management and prognosis in the clinical work. Two hundred and seven children with vocal fold paralysis in Children's Hospital of Fudan University were retrospectively studied, and followed-up. Read More

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November 2018
3 Reads

Pseudotumor cerebri and lung cancer-associated jugular vein thrombosis: Role of anatomical variations of torcular herophili.

eNeurologicalSci 2018 Dec 2;13:18-20. Epub 2018 Nov 2.

Laboratory of Neural Circuitry, Graduate School of Brain Science, Doshisha University, Japan.

A 71-year-old male appeared at the facility complaining of disturbance of consciousness and bilateral papilledema. The laboratory test revealed anemia and coagulation abnormality. A physical examination and magnetic resonance imaging (MRI) of the brain with and without gadolinium showed no abnormalities. Read More

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http://dx.doi.org/10.1016/j.ensci.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222035PMC
December 2018
1 Read

A study of clinical, radiological and etiological profile of cerebral venous sinus thrombosis at a tertiary care center.

Med J Armed Forces India 2018 Oct 16;74(4):326-332. Epub 2017 Dec 16.

Resident (Medicine), INHS Asvini, Mumbai, India.

Background: A prospective, observational study was done at a tertiary care hospital in Western Maharashtra to describe the etiologies, clinical features, diagnosis and prognosis of cerebral venous sinus thrombosis in an Indian population.

Methods: 54 patients with clinical and MRI features suggestive of cerebral venous sinus thrombosis (CVST), were studied with detailed clinical evaluation and pro-thrombotic work up. All were followed up monthly for 6 months, to assess the response to therapy and clinical outcomes. Read More

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http://dx.doi.org/10.1016/j.mjafi.2017.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224650PMC
October 2018
3 Reads

Fluid-structure Interaction in the Cerebral Venous Transverse Sinus.

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:4544-4547

The biomechanics of the cerebral venous system plays an important role in determining blood flow to the brain. Computational approaches to help elucidate the role of the cerebral venous system in health and disease have largely focused on lumped-parameter models and one-dimensional computational fluid dynamics simulations. To expand upon the prior work, and to investigate the possible role of cerebral venous collapse in normal physiology and pathological conditions, we developed a fluid-structure interaction (FSI) model of the cerebral venous transverse sinus (TS), coupled to a lumpedparameter representation of the upstream cerebral circulation to provide boundary conditions for the FSI simulation. Read More

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http://dx.doi.org/10.1109/EMBC.2018.8513150DOI Listing

Preoperative management of spontaneous cerebrospinal fluid rhinorrhea with acetazolamide.

Int Forum Allergy Rhinol 2018 Nov 15. Epub 2018 Nov 15.

University of Virginia School of Medicine, Charlottesville, VA.

Background: Spontaneous cerebrospinal fluid (CSF) rhinorrhea has been associated with elevated intracranial pressure (ICP). As such, ICP reducing measures are commonly employed to optimize repair. Although postoperative acetazolamide use has been described, no data currently exists on the potential for preoperative use. Read More

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http://doi.wiley.com/10.1002/alr.22245
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http://dx.doi.org/10.1002/alr.22245DOI Listing
November 2018
5 Reads

Stent Survival and Stent-Adjacent Stenosis Rates following Venous Sinus Stenting for Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis.

Interv Neurol 2018 Oct 31;7(6):490-500. Epub 2018 Jul 31.

Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.

Background: Idiopathic intracranial hypertension (IIH) is characterized by an elevated intracranial pressure without any identifiable causative factor such as an intracranial mass. Dural venous sinus stenosis (DVSS) has been suggested to be associated with IIH.

Objective: We performed an updated systematic review and meta-analysis to determine clinical outcomes as well as stent survival and stent-adjacent stenosis rates in patients undergoing DVSS for the management of medically refractory IIH. Read More

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https://www.karger.com/Article/FullText/490578
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http://dx.doi.org/10.1159/000490578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216784PMC
October 2018
3 Reads

Incidence of idiopathic intracranial hypertension in Fife.

Scott Med J 2018 Nov 5:36933018809727. Epub 2018 Nov 5.

3 Consultant Ophthalmologist, NHS Fife, UK.

Background And Aims: Idiopathic intracranial hypertension is a clinical syndrome of intracranial hypertension with normal cerebrospinal fluid in the absence of a mass lesion or hydrocephalus on brain imaging. Headache is the most common symptom of idiopathic intracranial hypertension, and about 10-15% of patients suffer from irreversible visual impairment. Previous estimates of the annual incidence of idiopathic intracranial hypertension vary worldwide from 0. Read More

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http://dx.doi.org/10.1177/0036933018809727DOI Listing
November 2018
6 Reads

Efficacy of stenting in patients with cerebral venous sinus thrombosis-related cerebral venous sinus stenosis.

J Neurointerv Surg 2018 Nov 2. Epub 2018 Nov 2.

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Background: Venous stenting has been proven to be a safe and effective therapeutic option for patients with idiopathic intracranial hypertension (IIH) and cerebral venous sinus stenosis (CVSS). However, its use in patients with cerebral venous sinus thrombosis-related CVSS has been less reported.

Purpose: To explore the safety and efficacy of stenting for patients with cerebral venous sinus thrombosis (CVST)-related CVSS. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014328DOI Listing
November 2018
1 Read

Clinical Features of Pediatric Idiopathic Intracranial Hypertension and Applicability of New ICHD-3 Criteria.

Front Neurol 2018 28;9:819. Epub 2018 Sep 28.

Child Neurology Unit, Department of Neuroscience and Neurorehabilitation, Headache Center, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Idiopathic intracranial hypertension (IIH) is characterized by intracranial pressure >28 cmHO in the absence of identifiable causes. Aim of this paper is to describe the clinical phenotype of pediatric IIH and to analyze the applicability of ICHD-3 criteria in comparison to the ICHD-2. We conducted a retrospective analysis of full clinical data of pediatric patients diagnosed with IIH between January 2007 and June 2018. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2018.00819
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http://dx.doi.org/10.3389/fneur.2018.00819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190892PMC
September 2018
5 Reads

The expanding burden of idiopathic intracranial hypertension.

Eye (Lond) 2018 Oct 24. Epub 2018 Oct 24.

Birmingham Neuro-Ophthalmology Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2TH, UK.

Objective: To quantify the hospital burden and health economic impact of idiopathic intracranial hypertension.

Methods: Hospital Episode Statistics (HES) national data was extracted between 1st January 2002 and 31st December 2016. All those within England with a diagnosis of idiopathic intracranial hypertension were included. Read More

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http://www.nature.com/articles/s41433-018-0238-5
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http://dx.doi.org/10.1038/s41433-018-0238-5DOI Listing
October 2018
10 Reads

B-Mode Transorbital Ultrasonography for the Diagnosis of Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis.

Ultraschall Med 2018 Oct 22. Epub 2018 Oct 22.

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.

In patients with idiopathic intracranial hypertension (IIH), transorbital sonography (TOS) may reveal an enlargement of the optic nerve sheath diameter (ONSD) and the presence of optic disc elevation (ODE), as a sign of an increase in intracranial pressure (ICP). We systematically reviewed the TOS findings in adults with IIH. MEDLINE, EMBASE, Cochrane Library and CENTRAL (1966 - May 2017) were searched to identify studies reporting data on patients with IIH assessed by B mode-TOS. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0719-4903
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http://dx.doi.org/10.1055/a-0719-4903DOI Listing
October 2018
3 Reads

Assessment of variations in sphenoid sinus pneumatization in Indian population: A multidetector computed tomography study.

Indian J Radiol Imaging 2018 Jul-Sep;28(3):273-279

Department of Radiodiagnosis, Pushpagiri Institute of Medical Sciences and Research Centre, Thiruvalla, Kerala, India.

Background And Purpose: The purpose of our study was to assess the prevalence of variations in the extent of sphenoid pneumatization in the Indian population and compare with existing literature.

Materials And Methods: This retrospective study included 500 patients who underwent CT of the paranasal sinuses. The multiplanar reformations of paranasal sinus were assessed for the type of pneumatization of the sphenoid sinus and type of clival, lateral recess, lesser wing, and anterior recess extensions. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_70_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176678PMC
October 2018
1 Read

Atypical Anti-MOG syndrome with aseptic meningoencephalitis and pseudotumor cerebri-like presentations.

Mult Scler Relat Disord 2018 Oct 3;27:30-33. Epub 2018 Oct 3.

UT Southwestern Medical Center, 5323 Harry Hines Blvd Dallas, Texas, TX 75235, United States.

Objective: To describe 2 atypical cases with Anti-MOG antibody related demyelinating syndrome.

Methodology: Case series.

Results: We present two cases. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22110348183036
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http://dx.doi.org/10.1016/j.msard.2018.10.003DOI Listing
October 2018
2 Reads

Obstructive Sleep Apnea in Neuro-Ophthalmology.

J Neuroophthalmol 2018 Oct 8. Epub 2018 Oct 8.

Save Sight Institute, Discipline of Ophthalmology, Faculty of Medicine and Health Sciences, University of Sydney, Sydney, Australia; Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

Background: Obstructive sleep apnea (OSA) is a common pulmonary disorder with many systemic sequelae. Its association with diseases seen in neuro-ophthalmology is being increasingly recognized. Treatment of OSA with continuous positive airway pressure (CPAP) may reverse the pathology in some eye diseases. Read More

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http://Insights.ovid.com/crossref?an=00041327-900000000-9920
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http://dx.doi.org/10.1097/WNO.0000000000000728DOI Listing
October 2018
2 Reads
1.810 Impact Factor

European headache federation guideline on idiopathic intracranial hypertension.

J Headache Pain 2018 Oct 8;19(1):93. Epub 2018 Oct 8.

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston, UK.

Background: Idiopathic Intracranial Hypertension (IIH) is characterized by an elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely unknown, however observations made in a number of recent clinical studies are increasing the understanding of the disease and now provide the basis for evidence-based treatment strategies.

Methods: The Embase, CDSR, CENTRAL, DARE and MEDLINE databases were searched up to 1st June 2018. Read More

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http://dx.doi.org/10.1186/s10194-018-0919-2DOI Listing
October 2018
6 Reads

Delayed presentation of iatrogenic ventriculoperitoneal shunt transection following laparoscopic weight loss surgery in a patient with idiopathic intracranial hypertension.

Ann R Coll Surg Engl 2018 Oct 5:e1-e3. Epub 2018 Oct 5.

King's College Hospital, Department of Neurosurgery , London , UK.

Idiopathic intracranial hypertension is strongly associated with central obesity and consequential raised intra-abdominal pressure. If left untreated it poses significant risk to vision and can eventually cause blindness. Owing to its pathophysiology, this condition is managed by both medical and surgical specialities. Read More

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http://dx.doi.org/10.1308/rcsann.2018.0147DOI Listing
October 2018
1 Read

Intracranial Hypertension Secondary to Cervical Dural Arteriovenous Fistula.

Asian J Neurosurg 2018 Jul-Sep;13(3):854-857

Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, L9 7LJ, UK.

Idiopathic intracranial hypertension (IIH) is a disease of mainly unknown etiology. Latest theories as to the pathogenesis have postulated a final common pathway of cerebral venous hypertension secondary to venous outflow impairment leading to decreased cerebrospinal fluid absorption. We present the case of a 42-year-old female who was treated for several years for headache and for approximately 12 months for IIH until appropriate imaging showed a right-sided cervical dural arteriovenous fistula (AVF) at the level of C4. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_328_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159076PMC
October 2018
1 Read

Co-occurrence of acute ophthalmoplegia (without ataxia) and idiopathic intracranial hypertension.

Eur J Ophthalmol 2018 Oct 3:1120672118803532. Epub 2018 Oct 3.

University of Malaya, Kuala Lumpur, Malaysia.

Background: Acute ophthalmoparesis without ataxia was designated as 'atypical Miller Fisher syndrome' as it presents with progressive, relatively symmetrical ophthalmoplegia, but without ataxia nor limb weakness, in the presence of anti-GQ1b antibody. Idiopathic intracranial hypertension is characterized by signs of raised intracranial pressure occurring in the absence of cerebral pathology, with normal composition of cerebrospinal fluid and a raised opening pressure of more than 20 cmHO during lumbar puncture. We aim to report a rare case of acute ophthalmoplegia with co-occurrence of raised intracranial pressure. Read More

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http://journals.sagepub.com/doi/10.1177/1120672118803532
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http://dx.doi.org/10.1177/1120672118803532DOI Listing
October 2018
3 Reads

Epidural Blood Patch for Postdural Puncture Headache due to Lumboperitoneal Shunt Placement in a Patient With Pseudotumor Cerebri: A Case Report.

A A Pract 2018 Sep 26. Epub 2018 Sep 26.

From the Department of Anesthesiology, University of Kansas Medical Center, Kansas City, Kansas.

The epidural blood patch (EBP) is commonly used to treat postdural puncture headaches (PDPHs) from spinal anesthesia, dural puncture with epidural anesthesia, and diagnostic and therapeutic lumbar puncture. We present a case of a patient with pseudotumor cerebri (idiopathic intracranial hypertension) who had a lumboperitoneal shunt placed for persistent headaches and subsequently developed symptoms similar to a PDPHs that were successfully treated with an EBP. While the exact mechanism by which our patient was experiencing PDPH symptoms is unknown, the EBP administration proved to be both therapeutic and diagnostic by ruling out shunt catheter malfunction through a resolution of symptoms. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000897DOI Listing
September 2018
3 Reads

Telemetry in intracranial pressure monitoring: sensor survival and drift.

Acta Neurochir (Wien) 2018 Nov 29;160(11):2137-2144. Epub 2018 Sep 29.

Clinic of Neurosurgery, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Background: Telemetric intracranial pressure (ICP) monitoring enable long-term ICP monitoring on patients during normal day activities and may accordingly be of use during evaluation and treatment of complicated ICP disorders. However, the benefits of such equipment depend strongly on the validity of the recordings and how often the telemetric sensor needs to be re-implanted. This study investigates the clinical and technical sensor survival time and drift of the telemetric ICP sensor: Raumedic Neurovent-P-tel. Read More

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http://link.springer.com/10.1007/s00701-018-3691-9
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http://dx.doi.org/10.1007/s00701-018-3691-9DOI Listing
November 2018
4 Reads

Changes in End-Tidal Carbon Dioxide Partial Pressure Alter Venous Sinus Pressure Measurements in Idiopathic Intracranial Hypertension.

World Neurosurg 2018 Dec 26;120:495-499. Epub 2018 Sep 26.

Department of Neurological Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Background: In the diagnosis of venous stenosis associated with idiopathic intracranial hypertension, previous studies have identified significant differences when venous pressures are measured under conscious sedation versus general anesthesia. No previous reports have investigated the effect that respiratory parameters may have on cerebral venous sinus pressure and the associated trans-stenosis pressure gradient.

Case Description: Two patients with idiopathic intracranial hypertension were retrospectively identified from a prospective database wherein venous manometry was performed as part of a venous stenting procedure with waveform recording during changes in end-tidal carbon dioxide level (EtCO). Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.117DOI Listing
December 2018

Prognostic value of JAK2V617F mutation in pseudotumor cerebri associated with cerebral venous sinus thrombosis.

Acta Neurol Scand 2018 Sep 25. Epub 2018 Sep 25.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objectives: To examine the clinical characteristics and prognosis of cerebral venous sinus thrombosis (CVST) that presented as pseudotumor cerebri (PTC) patients with JAK2V617F mutation.

Methods: Medical records of all consecutive patients that presented with PTC and a JAK2V617F mutation who were treated were retrospectively reviewed. Data regarding demographics and ocular presenting symptoms and signs, neurological signs, hematological factors treatment, and prognosis were collected. Read More

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http://dx.doi.org/10.1111/ane.13032DOI Listing
September 2018
6 Reads

Endovascular Treatment for Venous Sinus Stenosis in Idiopathic Intracranial Hypertension: An Observational Study of Clinical Indications, Surgical Technique, and Long-Term Outcomes.

World Neurosurg 2019 Jan 21;121:e165-e171. Epub 2018 Sep 21.

Norton Neuroscience Institute, Norton Healthcare, Louisville, Kentucky, USA. Electronic address:

Background: Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure. IIH causes significant morbidity marked by incapacitating headaches and visual disturbances. This study investigated the long-term outcomes of venous sinus stenting in a large group of patients with IIH. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.070DOI Listing
January 2019
2.420 Impact Factor

A Population-Based, Case-Control Evaluation of the Association Between Hormonal Contraceptives and Idiopathic Intracranial Hypertension.

Am J Ophthalmol 2019 Jan 21;197:74-79. Epub 2018 Sep 21.

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:

Purpose: To determine if the use of oral contraceptive pills (OCP) and other hormonal contraceptives are associated with a higher incidence of idiopathic intracranial hypertension (IIH).

Design: Retrospective, population-based, case-control study.

Methods: Setting: Female IIH patients evaluated between January 1, 1990, and December 31, 2016 were identified using the Rochester Epidemiology Project (REP), a record-linkage system of medical records for all patient-physician encounters among Olmsted County, Minnesota, residents. Read More

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http://dx.doi.org/10.1016/j.ajo.2018.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291342PMC
January 2019
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Identifying Incidence of and Risk Factors for Fluoroscopy-Guided Lumbar Puncture and Subsequent Persistent Low-Pressure Syndrome in Patients With Idiopathic Intracranial Hypertension.

J Neuroophthalmol 2018 Sep 20. Epub 2018 Sep 20.

Department of Ophthalmology and Visual Sciences (PL, JBH, MOG, GPVS), Washington University School of Medicine, St. Louis, Missouri; Mallinckrodt Institute of Radiology (MG), Washington University School of Medicine, St. Louis, Missouri; and Department of Neurology (MG, GPVS), Washington University School of Medicine, St. Louis, Missouri.

Background: To explore the incidence of and potential risk factors for developing persistent low-pressure syndrome after lumbar puncture (LP) in patients with idiopathic intracranial hypertension (IIH), as measured by use of blood patches.

Methods: A retrospective chart review was conducted of patients with definitively diagnosed IIH by clinical examination and LP, comparing them to patients with multiple sclerosis (MS) as controls who also received diagnostic LPs. Demographic, clinical, and radiological data were collected for each patient. Read More

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http://Insights.ovid.com/crossref?an=00041327-900000000-9921
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http://dx.doi.org/10.1097/WNO.0000000000000719DOI Listing
September 2018
3 Reads

The role of lumboperitoneal shunts in managing chronic hydrocephalus with slit ventricles.

J Neurosurg Pediatr 2018 Sep 21:1-6. Epub 2018 Sep 21.

Departments of Neurosurgery and Pediatric Neurosurgery, Wayne State University School of Medicine and Children's Hospital of Michigan, Detroit; and.

Objective: Lumboperitoneal (LP) shunts have a role not only in pseudotumor cerebri, but also in patients with slit-like ventricles who are treated with CSF shunting on a chronic basis. Hesitation to utilize LP shunts is based on previous conventional beliefs including the tendency for overdrainage, difficulties accessing the shunt to tap or revise, and risk of progressive cerebellar tonsillar herniation. The authors hypothesized that the use of horizontal-vertical (HV) valves may reduce the risk of these complications, particularly overdrainage and development of Chiari malformation. Read More

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http://dx.doi.org/10.3171/2018.6.PEDS17642DOI Listing
September 2018
5 Reads
1.370 Impact Factor

Acetazolamide Mitigates Intracranial Pressure Spikes Without Affecting Functional Outcome After Experimental Hemorrhagic Stroke.

Transl Stroke Res 2018 Sep 17. Epub 2018 Sep 17.

Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.

Increased intracranial pressure (ICP) after stroke can lead to poor outcome and death. Novel treatments to combat ICP rises are needed. The carbonic anhydrase inhibitor acetazolamide diminishes cerebrospinal fluid (CSF) production, reduces ICP in healthy animals, and is beneficial for idiopathic intracranial hypertension patients. Read More

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http://link.springer.com/10.1007/s12975-018-0663-6
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http://dx.doi.org/10.1007/s12975-018-0663-6DOI Listing
September 2018
5 Reads

Familial Occurrence of Idiopathic Intracranial Hypertension.

Isr Med Assoc J 2018 Sep;20(9):557-560

Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Idiopathic intracranial hypertension (IIH) is a disorder of unknown etiology. Its occurrence in the general population is 1/100,000, and 20/100,000 among overweight women of childbearing age. Familial occurrence is reportedly uncommon and not well-characterized. Read More

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September 2018
7 Reads

Impaired drainage of vein of Labbé following venous sinus stenting for idiopathic intracranial hypertension.

J Neurointerv Surg 2018 Sep 15. Epub 2018 Sep 15.

Division of Interventional Neuroradiology, Department of Neurological Surgery, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, USA.

Purpose: The impact of venous sinus stenting (VSS) on vein of Labbé (VOL) drainage is poorly understood. The purpose of the study is to examine the incidence and potential high risk factors of impaired VOL drainage among idiopathic intracranial hypertension (IIH) patients following VSS.

Materials And Methods: Institutional review board approved prospective evaluation of all IIH patients who underwent VSS over a 5 year period (January 2012 to December 2017) at Weill Cornell Medical Center constituted the study population. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014153DOI Listing
September 2018
1 Read