5,018 results match your criteria Idiopathic Intracranial Hypertension


Quality of life, need for retreatment, and the re-equilibration phenomenon after venous sinus stenting for idiopathic intracranial hypertension.

J Neurointerv Surg 2020 Jul 1. Epub 2020 Jul 1.

Neurological Surgery, Wake Forest University, Winston-Salem, North Carolina, United States

Background: Long term failure rates after venous sinus stenting (VSS) for idiopathic intracranial hypertension (IIH) are poorly understood.

Methods: Retrospective analysis was performed on a prospectively-maintained single center database to identify patients with medically refractory IIH who underwent VSS. Patients with persistent or severe recurrent symptoms after VSS undergo lumbar puncture (LP), therefore LP serves as a marker for treatment failure. Read More

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http://dx.doi.org/10.1136/neurintsurg-2020-016124DOI Listing

Antipsychotic pitfalls: idiopathic intracranial hypertension and antipsychotic-induced weight gain.

Authors:
Hirofumi Namiki

BMJ Case Rep 2020 Jun 30;13(6). Epub 2020 Jun 30.

Tokachi-Ikeda Community Center, Japan Association for Development of Community Medicine, Ikeda-cho, Nakagawa-gun, Hokkaido, Japan

Idiopathic intracranial hypertension (IIH) is a condition associated with poor vision and headaches that can cause disability and reduced quality of life. The onset of IIH is typically associated with sudden weight gain and obesity, which may be due to first-generation or second-generation antipsychotics. This case involved the use of quetiapine in an obese, 28-year-old woman; she gained significant weight after starting the antipsychotic and later developed headaches and blurred vision. Read More

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http://dx.doi.org/10.1136/bcr-2020-236161DOI Listing

Pseudotumor Cerebri in Young Children: Is It Different From Adults?

J Child Neurol 2020 Jun 29:883073820935720. Epub 2020 Jun 29.

Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1177/0883073820935720DOI Listing

Transverse venous sinus stenosis in idiopathic intracranial hypertension: a prospective pilot study.

Can J Ophthalmol 2020 Jun 23. Epub 2020 Jun 23.

Dalhousie University, Halifax, N.S.; Division of Neuroradiology, Department of Diagnostic Imaging, Nova Scotia Health Authority, Halifax, N.S.; Department of Radiology, University of Manitoba, Winnipeg, MB.. Electronic address:

Objective: Whether transverse venous sinus stenosis (TVSS) causes idiopathic intracranial hypertension (IIH) or is an effect of the increased intracranial pressures is controversial. The purpose of this study was to assess the feasibility of serial imaging in patients with IIH on medical management.

Design And Participants: Patients found to have IIH and TVSS on contrast-enhanced magnetic resonance venography (CEMRV) were recruited in a prospective cohort study. Read More

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http://dx.doi.org/10.1016/j.jcjo.2020.05.008DOI Listing

An Update on Imaging in Idiopathic Intracranial Hypertension.

Front Neurol 2020 10;11:453. Epub 2020 Jun 10.

Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Neuroimaging plays an essential role in the diagnostic workup of idiopathic intracranial hypertension with the aims to exclude secondary causes of elevated intracranial pressure and to identify imaging signs that are commonly observed in this disorder. As a valuable expansion of brain imaging, the imaging of the retina using optical coherence tomography has been of increasing value. In particular, this is the case with the latest devices that allow a more accurate distinction between a reduction in retinal nerve fiber layer thickness due to an improvement of papilledema or due to a worsening caused by optic nerve atrophy. Read More

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http://dx.doi.org/10.3389/fneur.2020.00453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297913PMC

Unilateral high myopia leading to asymmetric disc edema in idiopathic intracranial hypertension.

Authors:
Sumit Monga

Indian J Ophthalmol 2020 Jul;68(7):1475-1477

Centre for Sight Group of Eye Hospitals, Delhi NCR, India.

Asymmetrical disc edema in idiopathic intracranial hypertension (IIH) is an uncommon finding, with an unclear understanding. This report reinforces the importance of recognizing this entity in IIH diagnosis, and not misdiagnose the condition as unilateral disc edema. In this unique report, the causative association of asymmetric optic disc edema, with optic nerve kink, due to unilateral high myopia, is documented. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1799_19DOI Listing

Paradoxical response of intracranial pressure to shunt valve setting adjustments.

Acta Neurochir (Wien) 2020 Jun 24. Epub 2020 Jun 24.

Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, London, UK.

Background: The hydrodynamics of cerebrospinal fluid shunts have been described in vitro; however, knowledge on the response of intracranial pressure (ICP) to valve settings adjustments in vivo is limited. This study describes the effect of adjusting the shunt valve setting on ICP in a cohort of patients with complex symptom management.

Method: Single-centre retrospective observational study. Read More

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http://dx.doi.org/10.1007/s00701-020-04462-yDOI Listing

Optic Nerve Tortuosity in Idiopathic Intracranial Hypertension.

Intern Med 2020 Jun 23. Epub 2020 Jun 23.

Division of Neurology, Department of Internal Medicine, Showa University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.5086-20DOI Listing

Spontaneous CSF Leaks and IIH: A Flawless Connection? An Experience With 167 Patients.

Laryngoscope 2020 Jun 18. Epub 2020 Jun 18.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.

Objectives: Spontaneous cerebrospinal fluid (CSF) leaks are a rare but insidious clinical entity. In the recent literature, their pathogenesis has been linked with idiopathic intracranial hypertension (IIH). Considering a worse surgical outcome compared to traumatic leaks, a medical treatment of the underlying IIH has been suggested in order to prevent relapses. Read More

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http://dx.doi.org/10.1002/lary.28828DOI Listing

Optic nerve sheath fenestration via a supero-medial eyelid skin crease approach for the treatment of idiopathic intracranial hypertension in a UK population.

Eye (Lond) 2020 Jun 17. Epub 2020 Jun 17.

Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK.

Background/aims: Optic nerve sheath fenestration (ONSF) is a surgical intervention in the management of idiopathic intracranial hypertension (IIH) infrequently performed in the United Kingdom. Numerous surgical approaches have been described, including medial transconjunctival, lateral and endoscopic. We describe our outcomes and complications from ONSF via a supero-medial eyelid skin crease incision in patients with IIH. Read More

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http://dx.doi.org/10.1038/s41433-020-1024-8DOI Listing

Spontaneous Skull Base Cerebrospinal Fluid Leaks and Their Relationship to Idiopathic Intracranial Hypertension.

Am J Rhinol Allergy 2020 Jun 19:1945892420932490. Epub 2020 Jun 19.

Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.

Background: The association between spontaneous skull base cerebrospinal fluid (CSF) leaks and idiopathic intracranial hypertension (IIH) has been suggested, but its significance remains unclear.

Objective: To estimate the prevalence of IIH in spontaneous skull base CSF leak patients.

Methods: Systematic collection of demographics, neuro-ophthalmic and magnetic resonance imaging evaluation of spontaneous skull base CSF leak patients seen pre- and post-leak repair in one neuro-ophthalmology service. Read More

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http://dx.doi.org/10.1177/1945892420932490DOI Listing

Innominate vein stenosis causing raised intracranial pressure and blindness.

J Vasc Surg Cases Innov Tech 2020 Jun 6;6(2):282-284. Epub 2020 Jun 6.

UNC Rex Hospital, Raleigh, NC.

Central venous stenosis causing elevated intracranial pressure is a rare and potentially reversible cause of blindness in patients undergoing hemodialysis. We present the case of a 69-year-old man with progressive vision loss and raised intracranial pressure that was successfully treated with an innominate vein stent. Read More

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http://dx.doi.org/10.1016/j.jvscit.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283974PMC

Cerebrospinal Fluid Findings of 36 Adult Patients with Autism Spectrum Disorder.

Brain Sci 2020 Jun 8;10(6). Epub 2020 Jun 8.

Section for Experimental Neuropsychiatry, Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79085 Freiburg im Breisgau, Germany.

Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by difficulties with social interaction, repetitive behavior, and additional features, such as special interests. Its precise etiology is unclear. Recently, immunological mechanisms, such as maternal autoantibodies/infections, have increasingly been the subject of discussion. Read More

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http://dx.doi.org/10.3390/brainsci10060355DOI Listing

Female-to-male transgender patient with idiopathic intracranial hypertention.

J Neurol Sci 2020 Jun 3;415:116970. Epub 2020 Jun 3.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jns.2020.116970DOI Listing

COVID-19 and benign intracranial hypertension: A case report.

Rev Soc Bras Med Trop 2020 8;53:e20200325. Epub 2020 Jun 8.

Universidade Federal do Rio de Janeiro, Departamento de Radiologia, Rio de Janeiro, RJ, Brasil.

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http://dx.doi.org/10.1590/0037-8682-0325-2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294953PMC

Intra-dialytic intracranial pressure monitoring in a patient with lumbo-peritoneal shunt for idiopathic intracranial hypertension.

Br J Neurosurg 2020 Jun 9:1-3. Epub 2020 Jun 9.

Renal Unit, James Cook University Hospital, Middlesbrough, UK.

We present the case of a 25-year-old female with End-Stage Renal Disease (ESRD) and Idiopathic Intracranial Hypertension (IIH) who developed severe headaches during haemodialysis (HD). The headaches resolved several hours after each HD session. We were able to diagnose dialysis disequilibrium syndrome (DDS) following intracranial pressure (ICP) monitoring and use a novel strategy to treat her symptoms. Read More

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http://dx.doi.org/10.1080/02688697.2020.1774509DOI Listing

Neuroendovascular Cerebral Sinus Stenting in Idiopathic Intracranial Hypertension.

Interv Neurol 2020 Jan 4;8(2-6):164-171. Epub 2019 Jun 4.

Department of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, USA.

Idiopathic intracranial hypertension (IIH) is a rare, ill-understood disease of significant morbidity. Because the pathophysiology is poorly understood, treatment protocols are not uniform and are directed towards alleviating the most common symptoms: headache and visual loss. In this review, we analyze 25 case series, all of which included IIH patients ( = 408) who were treated with placement of a venous sinus stent. Read More

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http://dx.doi.org/10.1159/000500051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253862PMC
January 2020

Enlargement of Dorello's Canal as a Novel Radiographic Marker of Idiopathic Intracranial Hypertension.

J Neurol Surg B Skull Base 2020 Jun 3;81(3):232-236. Epub 2019 May 3.

Department of Otorhinolaryngology - Head and Neck Surgery, Rush Sinus Program, Rush University Medical Center, Chicago, Illinois, United States.

 The objective of this study is to compare the visibility and size of Dorello's canal (DC) on magnetic resonance imaging between patients with idiopathic intracranial hypertension (IIH) and control patients, for its evaluation as a potential novel marker for chronic increased intracranial pressure (ICP).  Retrospective blinded case-control study.  Tertiary care academic center. Read More

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http://dx.doi.org/10.1055/s-0039-1688783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253306PMC

Etiology of Papilledema in Patients in the Eye Clinic Setting.

JAMA Netw Open 2020 Jun 1;3(6):e206625. Epub 2020 Jun 1.

Department of Ophthalmology, Mayo Clinic College of Medicine, Rochester, Minnesota.

Importance: The study of health conditions associated with papilledema will augment the clinical judgment of eye care professionals treating patients with optic disc edema in determining the urgency of additional evaluation and counseling patients accordingly.

Objectives: To determine the incidence, demographic characteristics, and etiologies of papilledema based on a unique records-linkage research platform; and to describe the demographic and clinical differences between patients with idiopathic intracranial hypertension (IIH) and other causes of papilledema.

Design, Setting, And Participants: Retrospective population-based cross-sectional study of patients treated for papilledema at outpatient eye clinics in Olmsted County, Minnesota, using the Rochester Epidemiology Project. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.6625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267843PMC

Reductions in bilateral transverse sinus pressure gradients with unilateral transverse venous sinus stenting for idiopathic intracranial hypertension.

J Neurointerv Surg 2020 Jun 1. Epub 2020 Jun 1.

Radiology, Mayo Clinic, Rochester, MN, United States

Background: Venous sinus stenting is an effective treatment for papilledema associated with idiopathic intracranial hypertension (IIH). It is unclear whether unilateral transverse-sigmoid sinus (TSS) stenting adequately decompresses the contralateral TSS system in cases of bilateral transverse sinus stenosis. The objective of this study was to compare changes in bilateral TSS pressure gradients following unilateral TSS stenting in a series of patients with IIH. Read More

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http://dx.doi.org/10.1136/neurintsurg-2020-016170DOI Listing

Lumbo-peritoneal shunt as treatment modality for visual symptoms in idiopathic intracranial hypertension: A single institution experience.

Neurocirugia (Astur) 2020 May 29. Epub 2020 May 29.

Post Graduate Institute of Neurological Surgery, Dr. Achanta Lakshmipathi Neurosurgical Centre, Voluntary Health Services Multi-speciality Hospital & Research Centre, TTTI Post, Taramani, Chennai 600113, Tamil Nadu, India.

Objectives: To evaluate the efficacy of lumbo-peritoneal shunt (LPS) in patients of idiopathic intracranial hypertension presenting with visual symptoms.

Methods: Between Apr. 2014 and Mar. Read More

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http://dx.doi.org/10.1016/j.neucir.2020.03.001DOI Listing

Can dynamic memory changes represent an index of raised intracranial pressure in Idiopathic Intracranial Hypertension? From Luria to Higgins et al.

Med Hypotheses 2020 May 21;143:109832. Epub 2020 May 21.

Department of Neurosurgery, Epilepsy Surgery Unit, School of Medicine, Evangelismos Hospital, National and Kapodistrian University of Athens, Greece.

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http://dx.doi.org/10.1016/j.mehy.2020.109832DOI Listing

Unusual presentation of idiopathic intracranial hypertension.

BMJ Case Rep 2020 May 31;13(5). Epub 2020 May 31.

Mercy Health Hauenstein Neuroscience Center, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA.

Idiopathic intracranial hypertension typically presents with holocephalic headache associated with nausea, vomiting and bilateral papilledema. Involvement of the sixth cranial nerve is relatively common. The involvement of other cranial nerves, however, is rare in this disorder. Read More

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http://dx.doi.org/10.1136/bcr-2020-234741DOI Listing

Effect of Shunting on Visual Outcomes and Headache in Patients with Idiopathic Intracranial Hypertension.

World Neurosurg 2020 May 28. Epub 2020 May 28.

Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital forNeuroscience, Philadelphia, Pennsylvania, USA. Electronic address:

Background: Visual dysfunction and headache are major symptoms in patients with idiopathic intracranial hypertension (IIH).

Objective: We aim to evaluate the improvement of these symptoms in patients who underwent ventriculoperitoneal (VPS) and lumboperitoneal (LPS) shunting.

Methods: Electronic medical records were reviewed to identify baseline and treatment characteristics for patients diagnosed with IIH over ten years. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.186DOI Listing
May 2020
2.417 Impact Factor

An update on idiopathic intracranial hypertension in adults: a look at pathophysiology, diagnostic approach and management.

J Neurol 2020 May 27. Epub 2020 May 27.

Department "GF Ingrassia", Section of Neurosciences, University of Catania, Via Santa Sofia 78, 95123, Catania, Italy.

Idiopathic intracranial hypertension is a neurological syndrome determined by a rise in intracranial pressure without a detectable cause. Course and prognosis may be changeable, requiring a multidisciplinary approach for its diagnosis and management. Although its precise pathogenesis is still unknown, many studies have been carried out to define the possible causal and associated factors, such as retinoids, steroid hormones, body mass index and recent weight gains, cytokines and adipokines levels. Read More

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http://dx.doi.org/10.1007/s00415-020-09943-9DOI Listing

Psychiatric symptoms are frequent in idiopathic intracranial hypertension patients.

Neurosurg Rev 2020 May 26. Epub 2020 May 26.

Group of Cerebral Hydrodynamics, Division of Functional Neurosurgery, Institute of Psychiatry, Hospital das Clínicas, University of São Paulo, São Paulo, Brazil.

Idiopathic intracranial hypertension (IIH) is a rare disease with an incidence rate of 0.5-2.0/100,000/year. Read More

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http://dx.doi.org/10.1007/s10143-020-01321-3DOI Listing

The prevalence of papilledema in patients with migraine: a crucial cooccurrence of migraine and idiopathic intracranial hypertension.

Neurol Sci 2020 May 26. Epub 2020 May 26.

Department of Ophthalmology, Yozgat City Hospital, Yozgat, Turkey.

Objective: We aimed to investigate the prevalence of idiopathic intracranial hypertension (IIH) in patients with migraine by screening for papilledema.

Materials And Methods: We have included all the patients with migraine who applied to our neurology clinic during December 2019 and accepted to participate in the study. The demographic and clinical characteristics including migraine subtype (episodic/chronic), headache frequency per month, and headache characteristics of all patients were interrogated. Read More

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http://dx.doi.org/10.1007/s10072-020-04473-8DOI Listing

Infectious and inflammatory disorders might increase the risk of developing idiopathic intracranial hypertension - a national case-control study.

Cephalalgia 2020 May 25:333102420928079. Epub 2020 May 25.

Department of Clinical Neuroscience, Karolinska Institutet and Department of Neurology, Karolinska University Hospital, Sweden.

Objective: To investigate whether conditions causing inflammatory activation are associated with increased risk of idiopathic intracranial hypertension.

Methods: All newly diagnosed idiopathic intracranial hypertension patients (cases) in Sweden between 2000-2016 were identified using pre-determined algorithms (n = 902) and matched with five controls from the general population and five individuals with an obesity diagnosis (n = 4510) for age, sex, region, and vital status. National health registers provided information on infections, inflammatory disorders and dispensed medications. Read More

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http://dx.doi.org/10.1177/0333102420928079DOI Listing

The Role of Arachnoid Granulations and the Glymphatic System in the Pathophysiology of Idiopathic Intracranial Hypertension.

Curr Neurol Neurosci Rep 2020 May 22;20(7):20. Epub 2020 May 22.

Interventional Neuroradiology, Department of Neurological Surgery, Weill Cornell Medicine, New York, NY, USA.

Purpose Of Review: Idiopathic intracranial hypertension (IIH) is a disorder characterized by long-standing elevated intracranial pressure (ICP). As the name applies, no uniform cause has been identified. IIH is typically characterized by headaches, pulsatile tinnitus, and visual deterioration. Read More

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http://dx.doi.org/10.1007/s11910-020-01044-4DOI Listing

A systematic review on persistent trigeminal artery, in searching for a therapeutic solution to idiopathic and unresponsive trigeminal nerve inflammations and migraines.

J Biol Regul Homeost Agents 2019 Nov-Dec;33(6 Suppl. 2):155-169

Pham Ngoc Thac University of Medicine, Department of Histology, Embryology and Genetics, Ho Chi Minh City, Vietnam.

The rarely diagnosed persistent trigeminal artery (PTA) originates from the posterior bend or lateral wall of the intracavernous carotid artery and is the most common occurring type of remnant primitive fetal arteries. Even if PTA is uncommon, information and awareness about it could be of great help for clinicians dealing with cranial vascular imaging and operating this region. In addition, it could give a supporting response to the presence of a wide range of idiopathic and unresponsive disturbs that sometimes are erroneously interpreted and treated. Read More

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Update in Pediatric Pseudotumor Cerebri Syndrome.

Authors:
Shannon J Beres

Semin Neurol 2020 Jun 18;40(3):286-293. Epub 2020 May 18.

Department of Neurology and Ophthalmology, Stanford University, Palo Alto, California.

Pseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idiopathic, also known as idiopathic intracranial hypertension or primary intracranial hypertension, or can be secondary to medications and associated medical conditions. Given the threat to vision, early detection and treatment is needed in all age groups. Read More

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http://dx.doi.org/10.1055/s-0040-1708847DOI Listing

Idiopathic Intracranial Hypertension: Contemporary Management and Endovascular Techniques.

Semin Intervent Radiol 2020 Jun 14;37(2):175-181. Epub 2020 May 14.

Department of Radiology, University of Colorado School of Medicine, Aurora, Colorado.

Idiopathic intracranial hypertension (IIH) is a disease process of abnormally increased intracranial pressure in the absence of a mass lesion. Medical management, optic nerve fenestration, and surgical shunting procedures have failed to produce consistently successful results. In an unknown percentage of cases, IIH is caused by dural venous sinus obstruction which can be cured by endovascular treatment with dural venous sinus stent placement. Read More

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http://dx.doi.org/10.1055/s-0040-1709172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224981PMC

Neuroangiography: Review of Anatomy, Periprocedural Management, Technique, and Tips.

Semin Intervent Radiol 2020 Jun 14;37(2):166-174. Epub 2020 May 14.

Department of Neurosurgery, University of Colorado School of Medicine, Aurora, Colorado.

Neuroangiography (NA) is a minimally invasive procedure used to diagnose patients with neurovascular diseases. Noninvasive imaging has improved dramatically in recent years and is utilized more frequently; however, further evaluation with NA is still required in certain cases. NA indications include intracranial (cerebral aneurysms, arteriovenous malformations, dural arteriovenous fistula, cerebral vasculitis, cerebral vasospasm, ischemic stroke, nontraumatic subarachnoid hemorrhage, intracerebral hemorrhage, Moyamoya, vein of Galen malformation, intracranial tumors, and pseudotumor cerebri) and extracranial (internal and common carotid artery stenosis, vertebral artery stenosis, carotid artery blowout, vertebral artery blowout, epistaxis, oropharyngeal bleeding, and carotid body tumor) pathologies which can help with diagnosis and potential subsequent endovascular treatment. Read More

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http://dx.doi.org/10.1055/s-0040-1709171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224980PMC

Outcome of idiopathic intracranial hypertension after laparoscopic sleeve gastrectomy.

Surg Obes Relat Dis 2020 Apr 11. Epub 2020 Apr 11.

Ophthalmology Department, Alexandria University Faculty of Medicine, Alexandria, Egypt.

Background: Idiopathic intracranial hypertension (IIH) predominantly affects young, obese women and presents with signs and symptoms of increased intracranial pressure, such as headaches and visual impairment.

Objective: We aim to present our experience in the management of IIH.

Setting: University Hospital. Read More

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http://dx.doi.org/10.1016/j.soard.2020.03.032DOI Listing

Optical coherence tomography use in idiopathic intracranial hypertension.

Ann Eye Sci 2020 Mar 15;5. Epub 2020 Mar 15.

Department of Ophthalmology, Stanford University, Palo Alto, CA, USA.

Idiopathic intracranial hypertension (IIH) is a condition in which elevated pressure in the cerebrospinal fluid can lead to optic nerve head (ONH) dysfunction and subsequent visual impairment. Physicians are currently limited in their ability to monitor and manage this condition, as clinical symptoms and exam findings are often delayed in response to changes in intracranial pressure. In order to find other biomarkers of disease, researchers are using imaging modalities such as optical coherence tomography (OCT) to observe microscopic changes in the eye in this condition. Read More

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http://dx.doi.org/10.21037/aes.2019.12.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220123PMC

Transcranial Doppler for Monitoring and Evaluation of Idiopathic Intracranial Hypertension.

J Neurosci Rural Pract 2020 Apr 2;11(2):309-314. Epub 2020 May 2.

Department of Neurology, Ramaiah Medical College, Bengaluru, Karnataka, India.

 Idiopathic intracranial hypertension (IIH) is a disorder of unknown origin, characterized by features of raised intracranial pressure (ICP). Existing literature is inconclusive about the role of transcranial Doppler (TCD) in the management of IIH.  To study the TCD changes in IIH patients, pre- and post-cerebrospinal fluid (CSF) drainage. Read More

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http://dx.doi.org/10.1055/s-0040-1710086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214091PMC

Role of Adjunct Treatments for Idiopathic CSF Leaks After Endoscopic Repair.

Laryngoscope 2020 May 13. Epub 2020 May 13.

Department of Otolaryngology-Head & Neck Surgery, University of Miami-Miller School of Medicine, Miami, Florida, U.S.A.

Objective: A higher incidence of recurrent cerebrospinal fluid (CSF) leaks has been reported with idiopathic CSF leaks. A growing number of institutions advocate for routine use of intracranial pressure-lowering adjunct treatments after endoscopic repair. We report our results in a patient cohort in which only symptomatic patients are subjected to further testing and treatment. Read More

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http://dx.doi.org/10.1002/lary.28720DOI Listing

Long-term Kinetic Papilledema Improvement After Venous Sinus Stenting in Idiopathic Intracranial Hypertension.

Clin Neuroradiol 2020 May 12. Epub 2020 May 12.

Department of Ophthalmology, Pitié-Salpêtrière Hospital, APHP, 47, Bd de l'Hôpital, 75013, Paris, France.

Background And Purpose: The aim of this study was to assess the safety and effectiveness of lateral sinus stenosis (LSS) stenting in patients with idiopathic intracranial hypertension (IIH) who are refractory to medical treatment, particularly focusing on visual outcomes including papilledema.

Material And Methods: Retrospective study of consecutive patients with IIH refractory to medical treatment who underwent LSS stenting. Clinical features, visual fields and optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thicknesses were assessed before stenting, at 1 month poststenting and at last follow-up. Read More

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http://dx.doi.org/10.1007/s00062-020-00908-zDOI Listing

Posterior Globe Flattening without Papilledema in Idiopathic Intracranial Hypertension.

Neuroophthalmology 2020 Apr 19;44(2):69-70. Epub 2019 Jun 19.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

A 64-year-old woman had a one-year history of transient visual obscurations in the left eye and was found to have left optic disc oedema with preserved visual function. She was diagnosed with unilateral papilloedema related to idiopathic intracranial hypertension. Magnetic resonance imaging of the orbits showed flattening of the globe in the right eye, which did not have disc oedema. Read More

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http://dx.doi.org/10.1080/01658107.2019.1604765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202410PMC

Central Venous Obstruction-Induced Intracranial Hypertension in Hemodialysis Patients: An Underrecognized Cause of Elevated Intracranial Pressure.

J Neuroophthalmol 2020 Jun;40(2):218-225

Departments of Neurology (DDM, SMT), Ophthalmology (DDM), Neurosurgery (DDM), and Indiana University School of Medicine, Indianapolis, Indiana.

Background: Central venous obstruction (stenosis or occlusion) is common in patients with renal failure on hemodialysis and may be associated with intracranial hypertension (IH). Causes include vein injury from an endoluminal device, lumen obstruction from a device or thrombus, external vein compression, and high venous flow leading to vein intimal hyperplasia. A combination of high venous flow and central venous obstruction can lead to intracranial venous hypertension, impaired cerebrospinal fluid (CSF) resorption, and subsequent IH. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000964DOI Listing

Endovascular Neuromodulation: Safety Profile and Future Directions.

Front Neurol 2020 24;11:351. Epub 2020 Apr 24.

Department of Medicine, Vascular Bionics Laboratory, Melbourne Brain Centre, The University of Melbourne, Melbourne, VIC, Australia.

Endovascular neuromodulation is an emerging technology that represents a synthesis between interventional neurology and neural engineering. The prototypical endovascular neural interface is the Stentrode, a stent-electrode array which can be implanted into the superior sagittal sinus via percutaneous catheter venography, and transmits signals through a transvenous lead to a receiver located subcutaneously in the chest. Whilst the Stentrode has been conceptually validated in ovine models, questions remain about the long term viability and safety of this device in human recipients. Read More

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http://dx.doi.org/10.3389/fneur.2020.00351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193719PMC

Hemifacial Spasm as a Rare Clinical Presentation of Idiopathic Intracranial Hypertension: Case Report and Literature Review.

Ann Otol Rhinol Laryngol 2020 May 11:3489420920319. Epub 2020 May 11.

Department of Otolaryngology - Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Objectives: To report a rare case of idiopathic intracranial hypertension (IIH) presenting with hemifacial spasm (HFS) and review the current literature.

Methods: Case report and literature review. The patient's medical record was reviewed for demographic and clinical data. Read More

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http://dx.doi.org/10.1177/0003489420920319DOI Listing

Assessment of the optic nerve using strain and shear-wave elastography in patients with pseudotumour cerebri.

Clin Radiol 2020 May 4. Epub 2020 May 4.

Department of Neurology, Kirikkale University School of Medicine, Kirikkale, Turkey.

Aim: To evaluate the optic nerve using strain elastography (SE) and shear-wave elastography (SWE) in idiopathic intracranial hypertension (IIH) patients in comparison to participants in the control group.

Materials And Methods: Eighty eyes were evaluated in 40 cases consisting of 20 IIH patients and 20 participants in the control group. This study was conducted using SE and SWE in addition optic nerve sonography measurements of participants in the IIH patient group and the control group. Read More

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http://dx.doi.org/10.1016/j.crad.2020.03.038DOI Listing

Influence of Optic Nerve Appearance on Visual Outcome in Pediatric Idiopathic Intracranial Hypertension.

Can J Neurol Sci 2020 May 4:1-5. Epub 2020 May 4.

Department of Ophthalmology, Emory University, Atlanta, GA, USA.

Objectives: To determine whether optic disc hemorrhages (ODH) and cotton wool spots (CWS) at presentation are associated with worse visual outcomes in pediatric patients with idiopathic intracranial hypertension (IIH).

Methods: Retrospective institutional review of 100 eyes of 50 consecutive pediatric IIH patients (aged 16 years or less) who had baseline optic disc photographs before or within 30 days of their diagnostic lumbar puncture and initiation of medical treatment. Optic disc photographs were independently graded by three ophthalmologists in a standardized manner. Read More

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http://dx.doi.org/10.1017/cjn.2020.89DOI Listing

Idiopathic Intracranial Hypertension Without Papilledema With Improvement in Visual Field Defect Following Optic Nerve Sheath Fenestration: Comment.

Authors:
Edward Margolin

J Neuroophthalmol 2020 Apr 30. Epub 2020 Apr 30.

Department of Ophthalmology and Vision Sciences and Department of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/WNO.0000000000000968DOI Listing

Styloidogenic jugular venous compression syndrome: a case report and review of the literature.

Childs Nerv Syst 2020 Apr 28. Epub 2020 Apr 28.

Department of Neurosurgery, University of Alabama at Birmingham, 1802 6th Avenue South, FOT 1001, Birmingham, AL, 35233, USA.

Background: Styloidogenic jugular venous compression syndrome (SJVCS) has been shown to present with a similar symptomatology to idiopathic intracranial hypertension (IIH) and is caused by compression of the internal jugular vein (IJV) between the lateral tubercle of C1 and the styloid process. Treatments including venous stenting and styloidectomy have been reported with good outcomes; however, treatment of a pediatric patient with SJVCS with styloidectomy has not previously been reported in the literature.

Case Report: A 12-year-old male presented with refractory positional headaches, nausea, and vomiting, and after, workup including lumbar puncture (LP) and intracranial pressure (ICP) monitoring was found to have intracranial hypertension associated with contralateral neck turning. Read More

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http://dx.doi.org/10.1007/s00381-020-04622-6DOI Listing

Single arm access venous sinus stenting (SAVeS) technique: Technical note.

Interv Neuroradiol 2020 Apr 27:1591019920920992. Epub 2020 Apr 27.

Division of Interventional Neuroradiology, Department of Neurological Surgery, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA.

Intracranial venous sinus stenting is gaining acceptance as an effective treatment for idiopathic intracranial hypertension (IIH). The typical approach is via femoral venous and arterial access for transvenous stenting with simultaneous angiography. These patients are at an above average risk for groin complications considering obesity is typically associated with IIH and the need for heparinization and dual antiplatelet therapy. Read More

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http://dx.doi.org/10.1177/1591019920920992DOI Listing

A systematic review of surgical treatments of idiopathic intracranial hypertension (IIH).

Neurosurg Rev 2020 Apr 25. Epub 2020 Apr 25.

Department of Neurological Surgery, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA.

Idiopathic intracranial hypertension denotes raised intracranial pressure in the absence of an identifiable cause and presents with symptoms relating to elevated ICP, namely headaches and visual deterioration. Treatment of IIH aims at reducing intracranial pressure, relieving headache and salvaging patients' vision. Surgical interventions are recommended for medically refractory IIH and include CSF diversion techniques, optic nerve sheath fenestration, bariatric surgery and venous sinus stenting. Read More

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http://dx.doi.org/10.1007/s10143-020-01288-1DOI Listing