3,189 results match your criteria ISRN surgery[Journal]


Ceramic-on-Ceramic in Total Hip Replacement Revision.

Z Orthop Unfall 2018 06 27;156(3):272-280. Epub 2018 Feb 27.

Department of Orthopaedics and Trauma Surgery, Universitätsklinikum Bonn, Germany.

Background: The use of Ceramic-on-Ceramic (CoC) bearings in primary total hip arthroplasty (THA) is increasing and has been intensively analysed. This bearing plays a particularly relevant role in young, active patients and shows advantages over other bearings in biocompatibility, wear rate and lubrication properties. On the contrary, CoC bearings in revision THA are seldom used and scarcely analysed. Read More

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June 2018
3 Reads

Reconstructive Neurosurgery: A Challenge.

Acta Neurochir Suppl 2017 ;124:1-4

Institute of Neurosurgery, Medical School, Catholic University of Rome, Rome, Italy.

The International Society of Reconstructive Neurosurgery (ISRN) is an "open" multidisciplinary Society in evolution. Many different members of the Society inspire new trends in many different neurosurgical fields, all dealing with neurosurgical reconstruction.Spine and peripheral nerve reconstructive surgery, central nervous system revascularization (via surgery and interventional radiology), neuromodulation, bioengineering, and transplantation are recent tools used to promote reconstruction, restoration, and rehabilitation. Read More

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November 2017
7 Reads

n-Nucleotide circular codes in graph theory.

Philos Trans A Math Phys Eng Sci 2016 03;374(2063)

Faculty for Computer Sciences, Institute of Mathematical Biology, Mannheim University of Applied Sciences, Mannheim 68163, Germany.

The circular code theory proposes that genes are constituted of two trinucleotide codes: the classical genetic code with 61 trinucleotides for coding the 20 amino acids (except the three stop codons {TAA,TAG,TGA}) and a circular code based on 20 trinucleotides for retrieving, maintaining and synchronizing the reading frame. It relies on two main results: the identification of a maximal C(3) self-complementary trinucleotide circular code X in genes of bacteria, eukaryotes, plasmids and viruses (Michel 2015 J. Theor. Read More

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March 2016
7 Reads

Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial.

Lancet Neurol 2015 Apr 12;14(4):361-7. Epub 2015 Feb 12.

Background: Extracranial carotid and vertebral artery dissection is an important cause of stroke, especially in young people. In some observational studies it has been associated with a high risk of recurrent stroke. Both antiplatelet drugs and anticoagulant drugs are used to reduce risk of stroke but whether one treatment strategy is more effective than the other is unknown. Read More

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April 2015
6 Reads

Effects of Nitrate Supplementation on Cardiovascular and Autonomic Reactivity in African-American Females.

ISRN Physiol 2014 Feb;2014

Department of Physiology & Biophysics, Howard University College of Medicine, Washington, DC 20059, USA.

Previous studies have shown that beetroot juice (BJ) decreases systolic blood pressure (SBP) and oxygen demand. This study tests the hypothesis that a beetroot juice (BJ) treatment increases heart rate variability (HRV) measured by the average standard deviation of normal-normal electrocardiogram RR intervals (SDNN) and the low frequency (LF), mainly sympathetic, fast Fourier transform spectral index of HRV. The subjects were 13 healthy young adult African-American females. Read More

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February 2014
2 Reads

Construction and Characterization of Recombinant HSV-1 Expressing Early Growth Response-1.

ISRN Virol 2014 ;2014

Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland Eastern Shore, 1 College Backbone Road, Princess Anne, MD 21853, USA.

Early Growth response-1 (Egr-1) is a transcription factor that possesses a variety of biological functions. It has been shown to regulate HSV-1 gene expression and replication in different cellular environments through the recruitment of distinct cofactor complexes. Previous studies demonstrated that Egr-1 can be induced by HSV-1 infection in corneal cells but the level was lower compared to other cell types. Read More

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January 2014

Transformer 2β homolog (Drosophila) (TRA2B) regulates protein kinase C δI (PKCδI) splice variant expression during 3T3L1 preadipocyte cell cycle.

J Biol Chem 2014 Nov 26;289(46):31662-72. Epub 2014 Sep 26.

Department of Molecular Medicine, University of South Florida, Tampa, Florida 33612 From the James A. Haley Veterans Hospital and

Obesity is characterized by adipocyte hyperplasia and hypertrophy. We previously showed that PKCδ expression is dysregulated in obesity (Carter, G., Apostolatos, A. Read More

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November 2014
12 Reads

Knowledge and Perception of Stroke: A Population-Based Survey in Uganda.

ISRN Stroke 2014 ;2014

University Hospitals Case Medical Center, Neurological Institute Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA.

Purpose: This study, designed to complement a large population survey on prevalence of stroke risk factors, assessed knowledge and perception of stroke and associated factors.

Methods: A population survey was conducted in urban Nansana and rural Busukuma, Wakiso district, central Uganda. Adult participants selected by multistage stratified sampling were interviewed about selected aspects of stroke knowledge and perception in a pretested structured questionnaire. Read More

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January 2014
4 Reads

Role of Th17 Cells in the Pathogenesis of Human IBD.

Authors:
Julio Gálvez

ISRN Inflamm 2014 25;2014:928461. Epub 2014 Mar 25.

CIBER-EHD, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, Avenida del Conocimiento s/n, Granada, 18100 Armilla, Spain.

The gastrointestinal tract plays a central role in immune system, being able to mount efficient immune responses against pathogens, keeping the homeostasis of the human gut. However, conditions like Crohn's disease (CD) or ulcerative colitis (UC), the main forms of inflammatory bowel diseases (IBD), are related to an excessive and uncontrolled immune response against normal microbiota, through the activation of CD4(+) T helper (Th) cells. Classically, IBD was thought to be primarily mediated by Th1 cells in CD or Th2 cells in UC, but it is now known that Th17 cells and their related cytokines are crucial mediators in both conditions. Read More

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August 2014
1 Read

Emergence of bla TEM Type Extended-Spectrum β -Lactamase Producing Salmonella spp. in the Urban Area of Bangladesh.

ISRN Microbiol 2014 10;2014:715310. Epub 2014 Mar 10.

International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh.

Salmonellosis, an acute invasive enteric infection, is endemic in Bangladesh. We analyzed 128,312 stool samples of diarrheal patients to identify Salmonella spp. during 2005-2013. Read More

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August 2014
6 Reads
1 Citation

Cadmium Impairs p53 Activity in HepG2 Cells.

ISRN Toxicol 2014 13;2014:976428. Epub 2014 Mar 13.

Institute for Health and Consumer Protection, Joint Research Centre, Via Enrico Fermi 2749, 21027 Ispra, Italy.

Cadmium and cadmium compounds are contaminants of the environment, food, and drinking water and are important constituents of cigarette smoke. Cd exposure has also been associated with airborne particulate CdO and with Cd-containing quantum dots in medical therapy. Adverse cadmium effects reported in the literature have stimulated during recent years an ongoing discussion to better elucidate cadmium outcomes at cell and molecular level. Read More

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Alginate Particles as Platform for Drug Delivery by the Oral Route: State-of-the-Art.

Authors:
Alejandro Sosnik

ISRN Pharm 2014 9;2014:926157. Epub 2014 Apr 9.

Group of Pharmaceutical Nanomaterials Science, Department of Materials Science and Engineering, Technion-Israel Institute of Technology De-Jur Building, Office 607, Technion City, 32000 Haifa, Israel.

Pharmaceutical research and development aims to design products with ensured safety, quality, and efficacy to treat disease. To make the process more rational, coherent, efficient, and cost-effective, the field of Pharmaceutical Materials Science has emerged as the systematic study of the physicochemical properties and behavior of materials of pharmaceutical interest in relation to product performance. The oral route is the most patient preferred for drug administration. Read More

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August 2014
4 Reads

Orbital Volumetry in Graves' Orbitopathy: Muscle and Fat Involvement in relation to Dysthyroid Optic Neuropathy.

ISRN Ophthalmol 2014 2;2014:435276. Epub 2014 Apr 2.

Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark ; Eye Clinic 2061, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, Denmark.

Purpose. We wanted to investigate the relative significance of fat and muscle enlargement in the development of dysthyroid optic neuropathy (DON) in Graves' orbitopathy (GO). Methods. Read More

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Sarcoma excision and pattern of complicating sensory neuropathy.

ISRN Oncol 2014 24;2014:168698. Epub 2014 Mar 24.

Edinburgh Orthopaedic Trauma Unit, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK.

A potential complication of sarcoma excision surgery is a sensory neurological dysfunction around the surgical scar. This study utilised both objective and subjective sensation assessment modalities, to evaluate 22 patients after sarcoma surgery, for a sensory deficit. 93% had an objective sensory deficit. Read More

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August 2014
7 Reads

Mouse bone marrow-derived endothelial progenitor cells do not restore radiation-induced microvascular damage.

ISRN Cardiol 2014 27;2014:506348. Epub 2014 Mar 27.

Division of Biological Stress Response (H3), The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Background. Radiotherapy is commonly used to treat breast and thoracic cancers but it also causes delayed microvascular damage and increases the risk of cardiac mortality. Endothelial cell proliferation and revascularization are crucial to restore microvasculature damage and maintain function of the irradiated heart. Read More

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August 2014
12 Reads

Female asthma has a negative effect on fertility: what is the connection?

ISRN Allergy 2014 27;2014:131092. Epub 2014 Mar 27.

Respiratory Research Unit, Department of Respiratory Medicine, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark.

Reproductive changes such as impaired fertility and adverse pregnancy outcomes have been related to female asthma. We recently found that time to pregnancy is prolonged in asthmatic females especially in women with moderate to severe asthma and in those above 30 years of age. Despite their reproductive difficulties the asthmatics ultimately conceived just as many biological children as healthy throughout their reproductive lives. Read More

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August 2014
4 Reads

Prescreening with FOBT Improves Yield and Is Cost-Effective in Colorectal Screening in the Elderly.

ISRN Gastroenterol 2014 6;2014:179291. Epub 2014 Apr 6.

Division of Gastroenterology, Department of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, NY 11205, USA.

Background. Utilization of colonoscopy for routine colorectal cancer (CRC) screening in the elderly (patients over 75) is controversial. This study was designed to evaluate if using fecal occult blood test (FOBT) to select patients for colonoscopy can improve yield and be a cost- effective approach for the elderly. Read More

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August 2014
5 Reads

Present and possible therapies for age-related macular degeneration.

ISRN Ophthalmol 2014 16;2014:608390. Epub 2014 Apr 16.

Ophthalmology Department, University Hospital Aintree, Liverpool L9 7AL, UK.

Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly population worldwide and is defined as a chronic, progressive disorder characterized by changes occurring within the macula reflective of the ageing process. At present, the prevalence of AMD is currently rising and is estimated to increase by a third by 2020. Although our understanding of the several components underpinning the pathogenesis of this condition has increased significantly, the treatment options for this condition remain substantially limited. Read More

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August 2014
1 Read

Idelalisib for the treatment of chronic lymphocytic leukemia.

ISRN Oncol 2014 1;2014:931858. Epub 2014 Apr 1.

Department of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USA.

Chronic lymphocytic leukemia is the most common leukemia in the United States. It is a slowly progressive disease, with an 82% five-year survival rate. The treatment strategies are highly individualized with patients in the early and stable stages typically not requiring treatment. Read More

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August 2014
2 Reads

"Negotiating, navigating, and networking": three strategies used by nursing leaders to shape the adoption and incorporation of simulation into nursing curricula-a grounded theory study.

ISRN Nurs 2014 8;2014:854785. Epub 2014 Apr 8.

Department of Nursing, Faculty of Applied Health Sciences, Brock University, 500 Glenridge Drive, St. Catharines, ON, Canada L2S 3A1.

Background. Implementing simulation requires a substantial commitment of human and financial resources. Despite this, little is known about the strategies used by academic nursing leaders to facilitate the implementation of a simulation program in nursing curricula. Read More

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August 2014
6 Reads

Dental extraction can be performed safely in patients on aspirin therapy: a timely reminder.

Authors:
Gaurav Verma

ISRN Dent 2014 1;2014:463684. Epub 2014 Apr 1.

Department of Oral and Maxillofacial Surgery, Himachal Institute of Dental Sciences, Paonta Sahib, Himachal Pradesh 135001, India.

Cardiac patients on aspirin therapy may require extractions for their diseased teeth. It is a common practice among physicians and treating surgeons to stop aspirin prior to tooth extraction because of fear of bleeding complications. This practice often predisposes the patient to adverse thromboembolic events. Read More

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August 2014
1 Read

Is CT Angiogram of the Abdominal Vessels Needed following the Diagnosis of Ischemic Colitis? A Multicenter Community Study.

ISRN Gastroenterol 2014 12;2014:756926. Epub 2014 Feb 12.

Division of Gastroenterology, Department of Internal Medicine, Saint Francis Hospital, 355 Ridge Avenue, Evanston, IL 60202, USA.

Background. CT angiogram is frequently obtained after diagnosis of ischemic colitis (IC). Aims. Read More

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Antidepressant Effects of Mallotus oppositifolius in Acute Murine Models.

ISRN Pharmacol 2014 12;2014:324063. Epub 2014 Mar 12.

Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Objective. Hydroalcoholic extract of leaves of Mallotus oppositifolius (MOE), a plant used for CNS conditions in Ghana, was investigated for acute antidepressant effects in the forced swimming (FST) and tail suspension tests (TST). Results. Read More

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July 2014
3 Reads

Environmental Tobacco Smoke Exposure during Intrauterine Period, Promotes Caspase Dependent and Independent DNA Fragmentation in Sertoli-Germ Cells.

ISRN Obstet Gynecol 2014 12;2014:170124. Epub 2014 Mar 12.

Samsun 19 Mayıs University, Faculty of Medicine, 55220 Samsun, Turkey.

Objectives. To investigate the effect of cigarette smoke exposure during intrauterine period on neonatal rat testis. Methods. Read More

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July 2014
5 Reads

Investigation of Bacterial Cellulose Biosynthesis Mechanism in Gluconoacetobacter hansenii.

ISRN Microbiol 2014 16;2014:836083. Epub 2014 Mar 16.

School of Life Sciences, North Maharashtra University, P.O. Box 80, Jalgaon 425001, India.

The present study explores the mechanism of cellulose biosynthesis in Gluconoacetobacter hansenii. The cellulose synthase enzyme was purified as membrane fraction and solubilized by treatment with 0.1% digitonin. Read More

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July 2014
1 Read

Phagocytized neutrophil fragments in the bone marrow: a phenomenon most commonly associated with hodgkin lymphoma.

ISRN Hematol 2014 18;2014:363854. Epub 2014 Mar 18.

Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.

Bone marrow macrophages containing other cells, or large pieces of other cells, represent a distinctive feature of diseases such as Hemophagocytic Lymphohistiocytosis (HLH) and Rosai-Dorfman disease. We describe a distinct variation of phagocytic histiocyte morphology, featuring histiocytes containing predominantly fragments of neutrophil nuclei. We retrospectively reviewed initial bone marrow samples for Hodgkin lymphoma, Burkitt lymphoma, Ewing sarcoma, or evaluation for nonneoplastic conditions, scoring the presence or absence of the above-described histiocytes. Read More

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Anxiety, automatic negative thoughts, and unconditional self-acceptance in rheumatoid arthritis: a preliminary study.

ISRN Rheumatol 2014 20;2014:317259. Epub 2014 Mar 20.

Social Work Department, University "Eftimie Murgu" of Re ș i ț a, Train Vuia Square, No. 1-4, 320085 Re ș i ț a, Romania.

Objectives. This research was carried out in two stages: the objectives of the first stage were (1) to identify the existing relationships between the level of anxiety, the frequency of automatic negative thoughts, and unconditional self-acceptance and (2) to capture the existing differences regarding these variables between people diagnosed with rheumatoid arthritis and those with no such medical history. Methods. Read More

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Appetite sensations, appetite signaling proteins, and glucose in obese adolescents with subclinical binge eating disorder.

ISRN Obes 2014 11;2014:312826. Epub 2014 Mar 11.

Healthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, ON, Canada K1H 8L1 ; School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada K1N 6N5 ; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada K1N 6N5.

Objective. This study aimed to investigate potential differences in appetite sensations, ghrelin, peptide YY, and glucose and their relationship with energy and macronutrient intake in obese adolescents with subclinical binge eating disorder. Methods. Read More

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July 2014
7 Reads

Factors Determining Survival and Retention among HIV-Infected Children and Adolescents in a Community Home-Based Care and a Facility-Based Family-Centred Approach in Kampala, Uganda: A Cohort Study.

ISRN AIDS 2014 1;2014:852489. Epub 2014 Apr 1.

Department of Paediatrics, University of Padua, Via Giustiniani 3, 35128 Padua, Italy.

We describe factors determining retention and survival among HIV-infected children and adolescents engaged in two health care delivery models in Kampala, Uganda: one is a community home-based care (CHBC) and the other is a facility-based family-centred approach (FBFCA). This retrospective cohort study reviewed records from children aged from 0 to 18 years engaged in the two models from 2003 to 2010 focussing on retention/loss to follow-up, mortality, use of antiretroviral therapy (ART), and clinical characteristics. Kaplan Meier survival curves with log rank tests were used to describe and compare retention and survival. Read More

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Emergence of drug resistance in human immunodeficiency virus type 1 infected patients from pune, India, at the end of 12 months of first line antiretroviral therapy initiation.

ISRN AIDS 2014 10;2014:674906. Epub 2014 Apr 10.

National AIDS Research Institute (Indian Council of Medical Research), Pune, India.

Introduction. In India, 4,86,173 HIV infected patients are on first line antiretroviral therapy (ART) as of January 2012. HIV drug resistance (HIVDR) is drug and regimen-specific and should be balanced against the benefits of providing a given ART regimen. Read More

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July 2014
3 Reads
2 Citations

Rapid Tests versus ELISA for Screening of HIV Infection: Our Experience from a Voluntary Counselling and Testing Facility of a Tertiary Care Centre in North India.

ISRN AIDS 2014 7;2014:296840. Epub 2014 Apr 7.

Department of Microbiology, Maulana Azad Medical College, New Delhi 110002, India.

Early and accurate diagnosis of human immunodeficiency virus (HIV) infection is essential for timely identification of patients needing antiretroviral therapy and for instituting HIV prevention strategies. The primary methodology for HIV testing has shifted from enzyme linked immunosorbent assay (ELISA) to rapid diagnostic tests (RDTs) in recent years, especially in resource limited settings. However, the diagnostic performance of RDTs is a matter of concern. Read More

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July 2014
1 Read
5 Citations

Understanding the Profile of Tuberculosis and Human Immunodeficiency Virus Coinfection: Insights from Expanded HIV Surveillance at a Tuberculosis Facility in Durban, South Africa.

ISRN AIDS 2014 7;2014:260329. Epub 2014 Apr 7.

Department of Public Health Medicine, University of KwaZulu-Natal, Durban 4000, South Africa.

Background. Expanded HIV surveillance in TB patients forms part of the World Health Organization framework for strategic collaborative activity. Surveillance helps understand the epidemiology of the local dual epidemic and enables design of a tailored response to these challenges. Read More

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July 2014
1 Read

Substitution of soy protein for casein prevents oxidative modification and inflammatory response induced in rats fed high fructose diet.

ISRN Inflamm 2014 15;2014:641096. Epub 2014 Apr 15.

Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu 608002, India.

Fructose-rich diet is known to cause metabolic dysregulation, oxidative stress, and inflammation. We aimed to compare the effects of two dietary proteins of animal and plant origins on fructose-induced oxidative stress and inflammatory changes in liver. Wistar rats were fed either starch or fructose (60%) diet with casein or soy protein (20%) as the protein source for 8 weeks. Read More

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Ziprasidone as adjunctive therapy in severe bipolar patients treated with clozapine.

ISRN Psychiatry 2014 7;2014:904829. Epub 2014 Apr 7.

Dipartimento di Medicina Clinica e Sperimentale, Sezione di Psichiatria, Università di Pisa, Azienda Ospedaliero-Universitaria Pisana, Via Roma, No. 67, 56126 Pisa, Italy.

Aim. To confirm the efficacy and tolerability of ziprasidone as adjunctive therapy in bipolar patients partially responding to clozapine or with persisting negative symptoms, overweight, or with metabolic syndrome. Methods. Read More

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July 2014
3 Reads

Clinical practice guidelines in psychiatry: more confusion than clarity? A critical review and recommendation of a unified guideline.

ISRN Psychiatry 2014 31;2014:828917. Epub 2014 Mar 31.

Department of Psychiatry, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore 560029, India.

The discipline of psychiatry has a plethora of guidelines, designed to serve the needs of the clinician. Yet, even a cursory glance is enough to discern the differences between the various guidelines. This paper reviews the current standard guidelines being followed across the world and proposes a unified guideline on the backbone of current evidence and practice being followed. Read More

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July 2014
1 Read

Empathy in undergraduate medical students of bangladesh: psychometric analysis and differences by gender, academic year, and specialty preferences.

ISRN Psychiatry 2014 7;2014:375439. Epub 2014 Apr 7.

Department of Surgery, Diabetic Association Medical College, Faridpur, Bangladesh.

Empathy is considered to be associated with better patient compliance, satisfaction, and clinical outcomes. The aim of the study is to measure and examine empathy among a sample of undergraduate medical students of Bangladesh. It was a cross-sectional study and all the medical students of first through fifth year enrolled at Chattagram Maa-O-Shishu Hospital Medical College during the study period of 2014 were surveyed. Read More

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July 2014
1 Read
5 Citations

Prevalence and Genetic Characterization of Carbapenem- and Polymyxin-Resistant Acinetobacter baumannii Isolated from a Tertiary Hospital in Terengganu, Malaysia.

ISRN Microbiol 2014 19;2014:953417. Epub 2014 Mar 19.

Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Nosocomial infection caused by Acinetobacter baumannii is of great concern due to its increasing resistance to most antimicrobials. In this study, 54 nonrepeat isolates of A. baumannii from the main tertiary hospital in Terengganu, Malaysia, were analyzed for their antibiograms and genotypes. Read More

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July 2014
16 Reads

Function and Evolution of the Sox Multienzyme Complex in the Marine Gammaproteobacterium Congregibacter litoralis.

Authors:
Stefan Spring

ISRN Microbiol 2014 31;2014:597418. Epub 2014 Mar 31.

Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Inhoffenstraße 7B, 38124 Braunschweig, Germany.

Core sets of sox genes were detected in several genome sequenced members of the environmental important OM60/NOR5 clade of marine gammaproteobacteria. However, emendation of media with thiosulfate did not result in stimulation of growth in two of these strains and cultures of Congregibacter litoralis DSM 17192(T) did not oxidize thiosulfate to sulfate in concentrations of one mmol L(-1) or above. On the other hand, a significant production of sulfate was detected upon growth with the organic sulfur compounds, cysteine and glutathione. Read More

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July 2014
1 Read

High-amylose sodium carboxymethyl starch matrices: development and characterization of tramadol hydrochloride sustained-release tablets for oral administration.

ISRN Pharm 2014 8;2014:391523. Epub 2014 Apr 8.

Faculté de Pharmacie, Université de Montréal, P.O. Box 6128, Downtown Station, Montreal, QC, Canada H3C 3J7.

Substituted amylose (SA) polymers were produced from high-amylose corn starch by etherification of its hydroxyl groups with chloroacetate. Amorphous high-amylose sodium carboxymethyl starch (HASCA), the resulting SA polymer, was spray-dried to obtain an excipient (SD HASCA) with optimal binding and sustained-release (SR) properties. Tablets containing different percentages of SD HASCA and tramadol hydrochloride were produced by direct compression and evaluated for dissolution. Read More

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July 2014
2 Reads

Neutrophil-lymphocyte ratio in small renal masses.

ISRN Urol 2014 12;2014:759253. Epub 2014 Mar 12.

Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

Introduction. To evaluate the association between preoperative neutrophil-lymphocyte ratio (NLR) and clinicopathologic characteristics in patients with small renal masses (SRM). Methods. Read More

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July 2014
2 Reads

Alpha 1-adrenoceptor blocker may improve not only voiding but also storage lower urinary tract symptoms caused by (125) I brachytherapy for prostate cancer.

ISRN Urol 2014 30;2014:140654. Epub 2014 Mar 30.

Department of Urology, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Fukui 910-1193, Japan.

Purpose. To assess changes in lower urinary tract symptoms (LUTS) within 1 year after brachytherapy in patients receiving alpha 1-adrenoceptor antagonists. Methods. Read More

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July 2014
5 Reads

Three ports laparoscopic resection for colorectal cancer: a step on refining of reduced port surgery.

ISRN Surg 2014 12;2014:781549. Epub 2014 Mar 12.

Department of Surgical Oncology, National Cancer Institute, Cairo University, Cairo, Egypt.

Background. Reduced port surgery (RPS) is becoming increasingly popular for some surgeries. However, the application of RPS to the field of colectomy is still underdeveloped. Read More

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July 2014
3 Reads

An audit of operating room time utilization in a teaching hospital: is there a place for improvement?

ISRN Surg 2014 13;2014:431740. Epub 2014 Mar 13.

Department of Surgery, Faculty of Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.

Aim. To perform a thorough and step-by-step assessment of operating room (OR) time utilization, with a view to assess the efficacy of our practice and to identify areas of further improvement. Materials and Methods. Read More

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July 2014
7 Reads

Pathology slide review in vulvar cancer does not change patient management.

ISRN Surg 2014 25;2014:385386. Epub 2014 Mar 25.

Department of Gynecological Oncology, Erasmus Medical Center, Rotterdam, Cancer Institute, P.O. Box 5201, 3008 AE Rotterdam, The Netherlands.

Hypothesis. Pathology slide review in vulvar cancer is only necessary in a restricted number of cases. Methods. Read More

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July 2014
3 Reads

Perforation peritonitis and the developing world.

ISRN Surg 2014 2;2014:105492. Epub 2014 Apr 2.

Department of General Surgery, Lok Nayak Hospital, New Delhi 110002, India.

Background. Perforation peritonitis is the one of the commonest emergency encountered by surgeons. The aim of this paper is to provide an overview of the spectrum of perforation peritonitis managed in a single unit of a tertiary care hospital in Delhi. Read More

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July 2014
4 Reads

Association of auditory steady state responses with perception of temporal modulations and speech in noise.

ISRN Otolaryngol 2014 14;2014:374035. Epub 2014 Apr 14.

Department of Audiology & Speech Language Pathology, Kasturba Medical College, Manipal University, Mangalore, Karnataka 575 001, India.

Amplitude modulations in the speech convey important acoustic information for speech perception. Auditory steady state response (ASSR) is thought to be physiological correlate of amplitude modulation perception. Limited research is available exploring association between ASSR and modulation detection ability as well as speech perception. Read More

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July 2014
1 Read

The vestibular-auditory interaction for auditory brainstem response to low frequencies.

ISRN Otolaryngol 2014 31;2014:103598. Epub 2014 Mar 31.

Department of Audiology, Faculty of Rehabilitation, Hamadan University of Medical Sciences and Health Services, Hamadan 16657-696, Iran.

Since saccular projection is sound sensitive, the objective is to investigate the possibility that the saccular projections may contribute to auditory brainstem response to 500 HZ tone burst (ABR500 HZ). During the case-control research, twenty healthy controls compared to forty selected case groups as having chronic and resistant BPPV were evaluated in the audiology department of Hamadan University of Medical Sciences (Hamadan, Iran). Assessment is comprised of audiologic examinations, cervical vestibular evoked myogenic potentials (cVEMPs), and ABR500 HZ. Read More

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July 2014
1 Read

Aspheric intraocular lenses implantation for cataract patients with extreme myopia.

ISRN Ophthalmol 2014 19;2014:403432. Epub 2014 Mar 19.

Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, China.

Objective. To evaluate the postoperative visual quality of cataract patients with extreme myopia after implantation of aspheric intraocular lenses (IOLs). Methods. Read More

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July 2014
22 Reads

Survival prediction score: a simple but age-dependent method predicting prognosis in patients undergoing palliative radiotherapy.

ISRN Oncol 2014 19;2014:912865. Epub 2014 Mar 19.

Department of Oncology and Palliative Medicine, Nordland Hospital, 8092 Bodø, Norway ; Institute of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.

Purpose. Validation of a Canadian three-tiered prognostic model (survival prediction score, SPS) in Norwegian cancer patients referred for palliative radiotherapy (PRT), and evaluation of age-dependent performance of the model. Patients and Methods. Read More

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July 2014
13 Reads

Palliative Radiotherapy with or without Additional Care by a Multidisciplinary Palliative Care Team: A Retrospective Comparison.

ISRN Oncol 2014 30;2014:715396. Epub 2014 Mar 30.

Department of Oncology and Palliative Medicine, Nordland Hospital, 8092 Bodø, Norway.

Purpose. To analyze pattern of care and survival after palliative radiotherapy (RT) in patients managed exclusively by regular oncology staff or a multidisciplinary palliative care team (MPCT) in addition. Methods. Read More

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July 2014
4 Reads