108 results match your criteria ISRN cardiology[Journal]


Mouse bone marrow-derived endothelial progenitor cells do not restore radiation-induced microvascular damage.

ISRN Cardiol 2014 27;2014:506348. Epub 2014 Mar 27.

Division of Biological Stress Response (H3), The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Background. Radiotherapy is commonly used to treat breast and thoracic cancers but it also causes delayed microvascular damage and increases the risk of cardiac mortality. Endothelial cell proliferation and revascularization are crucial to restore microvasculature damage and maintain function of the irradiated heart. Read More

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http://dx.doi.org/10.1155/2014/506348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005028PMC
August 2014
12 Reads

Open versus Endovascular Repair of Abdominal Aortic Aneurysm in the Elective and Emergent Setting in a Pooled Population of 37,781 Patients: A Systematic Review and Meta-Analysis.

ISRN Cardiol 2014 2;2014:149243. Epub 2014 Apr 2.

Cardiology Service MCHE-MDC, Brooke Army Medical Center, 3551 Roger Brooke Drive, San Antonio, TX 78234-6200, USA.

Background. We evaluated the incidence of mortality and myocardial infarction (MI) in endovascular repair (EVAR) as compared to open aneurysm repair (OAR) in both elective and ruptured abdominal aortic aneurysm (AAA ) setting. Methods. Read More

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http://dx.doi.org/10.1155/2014/149243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004021PMC
July 2014
16 Reads
3 Citations

Exclusion of left atrial appendage thrombus using single phase coronary computed tomography as compared to transesophageal echocardiography in patients undergoing pulmonary vein isolation.

ISRN Cardiol 2014 20;2014:838727. Epub 2014 Feb 20.

Cardiology Service, Brooke Army Medical Center, 3551 Roger Brooke Drive, Fort Sam Houston, San Antonio, TX 78234-6200, USA.

Background. Transesophageal echocardiography (TEE) is used for the evaluation of the presence of left atrial appendage (LAA) thrombus prior to pulmonary vein isolation (PVI), while coronary computed tomography angiography (CCTA) is used for anatomic mapping during PVI. Methods. Read More

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http://dx.doi.org/10.1155/2014/838727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950652PMC
April 2014
9 Reads

Abdominal aortic aneurysms and coronary artery disease in a small country with high cardiovascular burden.

ISRN Cardiol 2014 20;2014:825461. Epub 2014 Feb 20.

Clinical Research, Hamad General Hospital, HMC, P.O. Box 3050, Doha, Qatar ; Clinical Medicine, Weill Cornell Medical School, P.O. Box 24144, Doha, Qatar ; Cardiology Unit, Internal Medicine, Ahmed Maher Teaching Hospital, Cairo, Egypt.

We aimed to evaluate the frequency, clinical profiles and outcomes of abdominal aortic aneurysms (AAA), and their association with coronary artery disease (CAD) in a small country with high cardiovascular burden. Methods. Data were collected for all adult patients who underwent abdominal computed tomography scans at Hamad General Hospital in Qatar between 2004 and 2008. Read More

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http://dx.doi.org/10.1155/2014/825461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950591PMC
April 2014
5 Reads

Myocardial injury in critically ill children: a case control study.

ISRN Cardiol 2014 11;2014:919150. Epub 2014 Feb 11.

Clinical Pathology Department, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.

Objectives. The aim of this study was to investigate the occurrence of myocardial injury in critically ill children through assessment of cardiac troponin T levels and whether levels are associated with disease severity and myocardial dysfunction measured by echocardiography. Methods. Read More

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http://dx.doi.org/10.1155/2014/919150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934765PMC
March 2014
6 Reads

Mitochondrial morphofunctional alterations in smooth muscle cells of aorta in rats.

ISRN Cardiol 2014 6;2014:739526. Epub 2014 Feb 6.

Cátedra de Física Biomédica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina ; Cátedra de Física Biomédica, Facultad de Ciencias Médicas, Universidad Nacional de La Rioja, La Rioja, Argentina ; Los Médanos 3155, Alto Verde, 5009 Córdoba, Argentina.

In an experimental model of atherogenesis induced by hyperfibrinogenemia (HF), the pharmacological response of vitamin E was studied in order to assess its antioxidant effect on the mitochondrial morphofunctional alterations in aortic smooth muscle cells. Three groups of male rats were used: (Ctr) control, (AI) atherogenesis induced for 120 days, and (AIE) atherogenesis induced for 120 days and treated with vitamin E. HF was induced by adrenalin injection (0. Read More

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http://dx.doi.org/10.1155/2014/739526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933528PMC
March 2014
4 Reads

Angiotensin receptor antagonists to prevent sudden death in heart failure: does the dose matter?

ISRN Cardiol 2014 6;2014:652421. Epub 2014 Feb 6.

Cardiology, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, Sapienza University, Via di Grottarossa 1035-39, 00189 Rome, Italy ; I.R.C.C.S. Neuromed, Pozzilli, Italy.

International guidelines recommend ICD implantation in patients with severe left ventricular dysfunction of any origin only after careful optimization of medical therapy. Indeed, major randomized clinical trials suggest that suboptimal use of fundamental drugs, such as ACE inhibitors (ACE-i) and beta-blockers, may affect ICD shock-free survival, sudden cardiac death (SCD), and overall mortality. While solid evidence in favour of pharmacological therapy based on ACE-i with or without beta-blockers is available, data on SCD in HF patients treated with angiotensin receptor blockers (ARBs) are limited. Read More

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http://www.hindawi.com/journals/isrn/2014/652421/
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http://dx.doi.org/10.1155/2014/652421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933036PMC
June 2014
8 Reads

Risks and Benefits of Thrombolytic, Antiplatelet, and Anticoagulant Therapies for ST Segment Elevation Myocardial Infarction: Systematic Review.

ISRN Cardiol 2014 6;2014:416253. Epub 2014 Feb 6.

Serviço de Cardiologia e Cirurgia Cardiovascular, Hospital das Clínicas da Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena 110, Campus Saúde, 30130-100 Belo Horizonte, MG, Brazil ; Departamento de Clínica Médica da Faculdade de Medicina da Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena 190, Campus Saúde, 30130-100 Belo Horizonte, MG, Brazil.

Objectives. Assess the impact of associating thrombolytics, anticoagulants, antiplatelets, and primary angioplasty (PA) on death, reinfarction (AMI), and major bleeding (MB) in STEMI therapy. Methods. Read More

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http://dx.doi.org/10.1155/2014/416253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933035PMC
June 2014
3 Reads

Evaluation of the Pericardium with CT and MR.

ISRN Cardiol 2014 29;2014:174908. Epub 2014 Jan 29.

St. Luke's Hospital, 915 East First Street, Duluth, MN 55805, USA.

The pericardium plays an important role in optimizing cardiac motion and chamber pressures and serves as a barrier to pathology. In addition to pericardial anatomy and function, this review article covers a variety of pericardial conditions, with mention of potential pitfalls encountered during interpretation of diagnostic imaging. Normal and abnormal appearance of pericardium on CT and MR imaging is emphasized, including dynamic imaging correlates of pericardial pathophysiology. Read More

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http://dx.doi.org/10.1155/2014/174908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926415PMC
June 2014
5 Reads

Doxapram hydrochloride aggravates adrenaline-induced arrhythmias accompanied by bidirectional ventricular tachycardia.

ISRN Cardiol 2014 9;2014:212045. Epub 2014 Jan 9.

Division of Clinical Pathophysiology, Graduate School of Health Sciences, Fujita Health University, 1-98 Dengakugakubo Kutsukake, Toyoake, Japan.

Objectives. Doxapram hydrochloride is a respiratory stimulant that has an inhibitory effect on myocardial IK1 potassium channels and is thought to increase membrane instability and excitability in myocardial cells. We examined the arrhythmogenic effects of doxapram hydrochloride in a rat model of halothane adrenaline-induced arrhythmia. Read More

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http://dx.doi.org/10.1155/2014/212045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912761PMC
February 2014
10 Reads

Attitudes of Implanting Physicians about Cardiac Rhythm Management Devices and Their Features.

ISRN Cardiol 2013 26;2013:247586. Epub 2013 Dec 26.

Frederik Meijer Heart & Vascular Institute and Spectrum Health, 2900 Bradford Street NE, Grand Rapids, MI 49525, USA ; Michigan State College of Human Medicine, Grand Rapids, MI 49525, USA.

Modern cardiac rhythm management systems have become increasingly complex. The decision on which specific system to implant in a given patient often rests with the implanting physician. We conducted a multiple-choice survey to assess the opinions and preferences of cardiologists and electrophysiologists who implant and follow cardiac rhythm management systems. Read More

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http://dx.doi.org/10.1155/2013/247586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888691PMC
February 2014
2 Reads

Hybrid surgical and catheter treatment for atrial fibrillation.

ISRN Cardiol 2013 Dec 16;2013:920635. Epub 2013 Dec 16.

Department of Cardiac Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, USA.

Advances in surgery for atrial fibrillation from cut and sew technique to thoracoscopy and new energy source have enabled minimally invasive approach which avoids median sternotomy and cardiopulmonary bypass. However, minimally invasive approach is unable to match the outcome of classic surgical technique due to difficulty in creating some of linear ablation lines. Hybrid procedure using catheter mapping and ablation in addition to minimally invasive surgical ablation has gained interest to combine the advantages of both procedures. Read More

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http://dx.doi.org/10.1155/2013/920635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876832PMC
December 2013
9 Reads

The Role of BNP and CRP in Predicting the Development of Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Surgery.

ISRN Cardiol 2013 Dec 25;2013:235018. Epub 2013 Dec 25.

1st Cardiology Department, Onassis Cardiac Surgery Center, Kallithea, 17674 Athens, Greece.

Objective. To evaluate the association of BNP and CRP with the development of postoperative atrial fibrillation following coronary artery bypass grafting surgery. Methods. Read More

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http://dx.doi.org/10.1155/2013/235018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886441PMC
December 2013
14 Reads

Relationship of plasma adiponectin levels with acute coronary syndromes and coronary lesion severity in north Indian population.

ISRN Cardiol 2013 10;2013:854815. Epub 2013 Dec 10.

Department of Cardiology, GB Pant Hospital and Associated Maulana Azad Medical College, Jawahar Lal Nehru Marg, New Delhi 110002, India.

Adiponectin is an adipocyte specific cytokine which, in contrast to other adipokines, has been described to have antiinflammatory, antithrombotic, and anti-atherogenic properties. This study evaluates the association between plasma adiponectin levels with acute coronary syndrome (ACS) and angiographic coronary lesion severity in Indian population. Ninety patients included in the study were divided in two groups in 1 : 1 ratio-patients admitted with a diagnosis of ACS and those without ACS. Read More

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https://www.hindawi.com/archive/2013/854815/
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http://dx.doi.org/10.1155/2013/854815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872405PMC
January 2014
7 Reads

Risk factors for asymptomatic ventricular dysfunction in rheumatoid arthritis patients.

ISRN Cardiol 2013 3;2013:635439. Epub 2013 Dec 3.

Massachusetts General Hospital Interpreter Services, Boston, MA 02114, USA.

Objective. The aim of the study was to describe echocardiographic abnormalities in patients with rheumatoid arthritis, concurrent systemic comorbidities, rheumatologic clinical activity, serologic markers of rheumatoid arthritis, and inflammatory activity. Methods. Read More

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http://dx.doi.org/10.1155/2013/635439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866864PMC
December 2013
9 Reads

Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin-Receptor Blockers (ARBs) in Patients at High Risk of Cardiovascular Events: A Meta-Analysis of 10 Randomised Placebo-Controlled Trials.

ISRN Cardiol 2013 Nov 6;2013:478597. Epub 2013 Nov 6.

Consultant Cardiologist, HT Ong Heart Clinic, 251C Burma Road, Penang 10350, Malaysia.

Context. Whether angiotensin converting-enzyme inhibitors (ACEI) and angiotensin-receptor blockers (ARB) are useful in high risk patients without heart failure is unclear. We perform a meta-analysis of prospective randomized placebo-controlled ACEI or ARB trials studying patients with a combination of risk factors to assess treatment impact on all cause mortality, cardiovascular mortality, nonfatal myocardial infarction (MI) and stroke. Read More

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http://dx.doi.org/10.1155/2013/478597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836383PMC
November 2013
32 Reads

Development of a closed chest model of chronic myocardial infarction in Swine: magnetic resonance imaging and pathological evaluation.

ISRN Cardiol 2013 27;2013:781762. Epub 2013 Oct 27.

Jesús Usón Minimally Invasive Surgery Centre, Carretera N-521, Km 41.8, 10071 Cáceres, Spain.

Our aim was to develop an easy-to-induce, reproducible, and low mortality clinically relevant closed-chest model of chronic myocardial infarction in swine using intracoronary ethanol and characterize its evolution using MRI and pathology. We injected 3-4 mL of 100% ethanol into the mid-LAD of anesthetized swine. Heart function and infarct size were assessed serially using MRI. Read More

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http://dx.doi.org/10.1155/2013/781762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825272PMC
November 2013
5 Reads

Human immunodeficiency virus and pulmonary arterial hypertension.

ISRN Cardiol 2013 Aug 21;2013:903454. Epub 2013 Aug 21.

Department of Internal Medicine, Saint Joseph Hospital, 2900 North Lake Shore, Chicago, LL 60657, USA.

Human immunodeficiency virus- (HIV-) related pulmonary arterial hypertension (PAH) is a rare complication of HIV infection. The pathophysiology of HIV-related PAH is complex, with viral proteins seeming to play the major role. However, other factors, such as coinfection with other microorganisms and HIV-related systemic inflammation, might also contribute. Read More

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http://dx.doi.org/10.1155/2013/903454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763567PMC
August 2013
7 Reads

Adequacy of cancer screening in adult women with congenital heart disease.

ISRN Cardiol 2013 1;2013:827696. Epub 2013 Aug 1.

Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Adults with congenital heart disease (ACHD) face noncardiac healthcare challenges as the population ages. We assessed whether women with ACHD have comparable cancer screening rates to non-ACHD women in a cardiac practice and to the general population. We performed a retrospective review of 175 adult women seen in a cardiac care center in 2009-2011. Read More

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http://www.hindawi.com/journals/isrn.cardiology/2013/827696/
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http://dx.doi.org/10.1155/2013/827696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747419PMC
August 2013
8 Reads

Association of oral health and cardiovascular disease risk factors "results from a community based study on 5900 adult subjects".

ISRN Cardiol 2013 9;2013:782126. Epub 2013 Jul 9.

Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Objectives. This study aimed to determine the association between some oral health status as a risk factor for cardiac diseases and other cardiovascular disease (CVD) risk factors in a sample of Iranian population in 2011. Methods. Read More

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http://dx.doi.org/10.1155/2013/782126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727197PMC
August 2013
21 Reads

Alcohol-attributable fraction of ischemic heart disease mortality in Russia.

Authors:
Y E Razvodovsky

ISRN Cardiol 2013 15;2013:287869. Epub 2013 Jul 15.

Grodno State Medical University, Gorky street 80, 230008 Grodno, Belarus.

Objective. The aim of the present study was to estimate the premature ischemic heart disease (IHD) mortality attributable to alcohol abuse in Russia on the basis of aggregate-level data of mortality and alcohol consumption. Method. Read More

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http://dx.doi.org/10.1155/2013/287869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728494PMC
August 2013
5 Reads

Assessment of Risk Factor for Cardiovascular Disease Using Heart Rate Variability in Postmenopausal Women: A Comparative Study between Urban and Rural Indian Women.

ISRN Cardiol 2013 11;2013:858921. Epub 2013 Jul 11.

K S Hegde Medical Academy, Nitte University, Mangalore 575 018, India.

Cardiovascular diseases are important causes of morbidity and mortality in postmenopausal women. A major determinant of cardiovascular health is the status of autonomic nervous system and assessment of Heart Rate Variability (HRV). Heart Rate Variability is a noninvasive and sensitive technique to evaluate cardiovascular autonomic control. Read More

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http://dx.doi.org/10.1155/2013/858921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725838PMC
August 2013
3 Reads

Risk factors for coronary drug-eluting stent thrombosis: influence of procedural, patient, lesion, and stent related factors and dual antiplatelet therapy.

ISRN Cardiol 2013 23;2013:748736. Epub 2013 Jun 23.

Abbott Vascular, Inc., Santa Clara, 3200 Lakeside Dr., Santa Clara, CA 95054-2807, USA ; Center for Cardiovascular Technology, Stanford University, Palo Alto, CA 94305-5637, USA.

The complication of stent thrombosis (ST) emerged at a rate of 0.5% annually for first-generation drug-eluting stents (DES), often presenting as death or myocardial infarction. Procedural factors such as stent underexpansion and malapposition are risk factors for ST in patients. Read More

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http://dx.doi.org/10.1155/2013/748736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706013PMC
July 2013
5 Reads

Left-to-Right Shunt with Congenital Heart Disease: Single Center Experience.

ISRN Cardiol 2013 23;2013:301617. Epub 2013 Jun 23.

Gazi University Medical Faculty Hospital, Department of Pediatric Cardiology, 06560 Ankara, Turkey.

Objective. The objective of this study was to determine the frequency of pulmonary arterial hypertension (PAH) in congenital heart disease (CHD) with an isolated, large left-to-right shunt and to indicate the factors in the development of PAH. Methods. Read More

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http://dx.doi.org/10.1155/2013/301617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706015PMC
July 2013
7 Reads

A review of most relevant complications of transcatheter aortic valve implantation.

ISRN Cardiol 2013 12;2013:956252. Epub 2013 May 12.

Department of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, 3400 Bainbridge Avenue, MAP 5, New York, NY 10467, USA.

Transcatheter aortic valve implantation (TAVI) has emerged for treating aortic stenosis in patients who are poor candidates for surgical aortic valve replacement. Currently, the balloon-expandable Edwards Sapien valve-which is usually implanted via a transfemoral or transapical approach-and the self-expanding CoreValve ReValving system-which is designed for retrograde application-are the most widely implanted valves worldwide. Although a promising approach for high-risk patients, the indication may be expanded to intermediate- and eventually low-risk patients in the future; however, doing so will require a better understanding of potential complications, risk factors for these complications, and strategies to individualize each patient to a different access route and a specific valve. Read More

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http://dx.doi.org/10.1155/2013/956252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703377PMC
July 2013
20 Reads

Dual antiplatelet therapy can be discontinued at three months after implantation of zotarolimus-eluting stent in patients with coronary artery disease.

ISRN Cardiol 2013 4;2013:518968. Epub 2013 Apr 4.

Department of Cardiology, Fukuyama City Hospital, 5-23-1 Zaou-chou, Fukuyama, Hiroshima 721-8511, Japan.

Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention increases the risk of bleeding. We studied the safety and clinical outcomes of switching from DAPT to aspirin monotherapy at 3 months after ZES implantation. We retrospectively evaluated 168 consecutive patients with coronary artery disease who had been implanted with a ZES from June 2009 through March 2010. Read More

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http://dx.doi.org/10.1155/2013/518968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649238PMC
June 2013
19 Reads

Elevated cardiac troponins in setting of systemic inflammatory response syndrome, sepsis, and septic shock.

Authors:
Nasir Hussain

ISRN Cardiol 2013 11;2013:723435. Epub 2013 Apr 11.

Saint Joseph Hospital, Presence Health, Department of Internal Medicine, 2900 North Lake Shore Drive, Chicago, IL 60657, USA.

Elevation of cardiac troponins and creatinine kinase is frequently observed in setting of systemic inflammatory response syndrome (SIRS), sepsis, or septic shock. Underlying pathophysiologic mechanism for such troponin leak, its clinical significance, and what different could be done in such settings remain elusive. In this paper we have briefly overviewed the proposed pathogenic mechanisms for SIRS, sepsis, or septic shock-related troponin elevation (SRTE) and have provided brief overview on its clinical significance. Read More

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http://dx.doi.org/10.1155/2013/723435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649176PMC
May 2013
5 Reads

The Transaxial Orientation Is Superior to Both the Short Axis and Horizontal Long Axis Orientations for Determining Right Ventricular Volume and Ejection Fraction Using Simpson's Method with Cardiac Magnetic Resonance.

ISRN Cardiol 2013 14;2013:268697. Epub 2013 Apr 14.

Department of Diagnostic Imaging, Rhode Island Hospital, Warren Alpert School of Medicine of Brown University, 593 Eddy Street, Providence, RI 02903, USA.

We sought to determine which of the three orientations is the most reliable and accurate for quantifying right ventricular (RV) volume and ejection fraction (EF) by cardiac magnetic resonance using Simpson's method. We studied 20 patients using short axis (SA), transaxial (TA), and horizontal long axis (HLA) orientations. Three readers independently traced RV endocardial contours at end-diastole and end-systole for each orientation. Read More

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http://dx.doi.org/10.1155/2013/268697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649247PMC
May 2013
9 Reads

Hyperoxic vasoconstriction of human pulmonary arteries: a novel insight into acute ventricular septal defects.

ISRN Cardiol 2013 31;2013:685735. Epub 2013 Mar 31.

Department of Cardiothoracic Surgery, Castle Hill Hospital, Cottingham HU16 5JQ, UK.

Objectives. Acute rises in pulmonary artery pressures following postinfarction ventricular septal defects present a challenge. We hypothesised that the abnormally high oxygen content exposure to the pulmonary arteries may be a factor. Read More

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http://dx.doi.org/10.1155/2013/685735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628186PMC
April 2013
12 Reads
2 Citations

Intracoronary adenosine versus intravenous adenosine during primary PCI for ST-elevation myocardial infarction: which one offers better outcomes in terms of microvascular obstruction?

ISRN Cardiol 2013 27;2013:248476. Epub 2013 Mar 27.

Cardiology Department, John Radcliffe Hospital, Oxford OX3 9DU, UK.

Aims. Previous studies have suggested that intravenous administration of adenosine improves myocardial reperfusion and reduces infarct size in ST-elevation myocardial infarction (STEMI) patients. Intracoronary administration of adenosine has shown conflicting results. Read More

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http://dx.doi.org/10.1155/2013/248476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623473PMC
April 2013
18 Reads

Diagnosis and treatment of asymptomatic left ventricular systolic dysfunction after myocardial infarction.

ISRN Cardiol 2013 12;2013:731285. Epub 2013 Mar 12.

Chair and Division of Cardiology, Policlinico Universitario "Paolo Giaccone", Palermo, Italy.

The increased survival after acute myocardial infarction induced an increase in heart failure with left ventricular systolic dysfunction. Early detection and treatment of asymptomatic left ventricular systolic dysfunction give the chance to improve outcomes and to reduce costs due to the management of patients with overt heart failure. Read More

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http://dx.doi.org/10.1155/2013/731285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610361PMC
April 2013
5 Reads

Amiodarone-induced cirrhosis of liver: what predicts mortality?

ISRN Cardiol 2013 14;2013:617943. Epub 2013 Mar 14.

Department of Internal Medicine, Saint Joseph Hospital, Resurrection Health Care, 2900 North Lake Shore Drive, Chicago, IL 60657, USA.

Introduction. Amiodarone has been used for more than 5 decades for the treatment of various tachyarrhythmias and previously for the treatment of refractory angina. There are multiple well-established side effects of amiodarone. Read More

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http://dx.doi.org/10.1155/2013/617943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612472PMC
April 2013
14 Reads

QRS Complex Enlargement as a Predictor of Ventricular Arrhythmias in Patients Affected by Surgically Treated Tetralogy of Fallot: A Comprehensive Literature Review and Historical Overview.

ISRN Cardiol 2013 20;2013:782508. Epub 2013 Feb 20.

Department of Medical Sciences "M. Aresu", University of Cagliari, Policlinico Universitario, S.S. 554, bivio di Sestu, Monserrato, 09042 Cagliari, Italy.

Tetralogy of Fallot (TOF) is a congenital heart disease frequently treated by surgical repair to relieve symptoms and improve survival. However, despite the performing of an optimal surgical repair, TOF patients are at times characterized by a poor long-term survival rate, likely due to cardiac causes such as ventricular arrhythmias, with subsequent sudden death. In the 80s it was irrefutably demonstrated that QRS prolongation ≥180 msec at basal electrocardiogram is a strong predictor for refining risk stratification for ventricular tachycardia in these patients. Read More

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http://dx.doi.org/10.1155/2013/782508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590565PMC
March 2013
4 Reads

Pathobiology of obstructive sleep apnea-related dyslipidemia: focus on the liver.

ISRN Cardiol 2013 2;2013:687069. Epub 2013 Jan 2.

Department of Internal Medicine, Saint Joseph Hospital, 2900 North Lake Shore, Chicago, IL 60657, USA.

Obstructive sleep apnea and dyslipidemia are common medical disorders that independently increase vascular morbidity and mortality. Current animal and human data show that, indeed, obstructive sleep apnea may mediate pathological alterations in cholesterol and triglyceride metabolism. The mechanisms involved are increased lipolysis, decreased lipoprotein clearance, and enhanced lipid output from the liver. Read More

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http://dx.doi.org/10.1155/2013/687069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549373PMC
January 2013
3 Reads

Changes in lipids and lipoprotein indices in relation to the severity of hypertension in newly diagnosed hypertensive nigerians.

ISRN Cardiol 2012 11;2012:972341. Epub 2012 Dec 11.

Department of Medicine, Nnamdi Azikiwe University Teaching Hospital, PMB 5025, Anambra State, Nnewi 435101, Nigeria.

Hypertension and dyslipidaemia are important components of metabolic syndrome and both are known to complicate each other. Materials and Methods. A total of 149 subjects consisting of 107 hypertensive patients, grouped into 3 (of 37, 35, and 35 patients categorized based on the grade of hypertension as grade 1, grade 2, and grade 3, resp. Read More

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http://dx.doi.org/10.5402/2012/972341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530229PMC
January 2013
3 Reads

Cardiac ion channelopathies and the sudden infant death syndrome.

Authors:
Ronald Wilders

ISRN Cardiol 2012 5;2012:846171. Epub 2012 Dec 5.

Department of Anatomy, Embryology and Physiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands.

The sudden infant death syndrome (SIDS) causes the sudden death of an apparently healthy infant, which remains unexplained despite a thorough investigation, including the performance of a complete autopsy. The triple risk model for the pathogenesis of SIDS points to the coincidence of a vulnerable infant, a critical developmental period, and an exogenous stressor. Primary electrical diseases of the heart, which may cause lethal arrhythmias as a result of dysfunctioning cardiac ion channels ("cardiac ion channelopathies") and are not detectable during a standard postmortem examination, may create the vulnerable infant and thus contribute to SIDS. Read More

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http://dx.doi.org/10.5402/2012/846171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529486PMC
January 2013
6 Reads

Depression and coronary heart disease.

ISRN Cardiol 2012 22;2012:743813. Epub 2012 Nov 22.

Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University, New York, NY 10032, USA.

There are exciting findings in the field of depression and coronary heart disease. Whether diagnosed or simply self-reported, depression continues to mark very high risk for a recurrent acute coronary syndrome or for death in patients with coronary heart disease. Many intriguing mechanisms have been posited to be implicated in the association between depression and heart disease, and randomized controlled trials of depression treatment are beginning to delineate the types of depression management strategies that may benefit the many coronary heart disease patients with depression. Read More

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http://dx.doi.org/10.5402/2012/743813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514821PMC
December 2012
9 Reads

Computational cardiology: the heart of the matter.

ISRN Cardiol 2012 14;2012:269680. Epub 2012 Nov 14.

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, 3400 North Charles Street, Hackerman Hall Room 216, Baltimore, MD 21218, USA.

This paper reviews the newest developments in computational cardiology. It focuses on the contribution of cardiac modeling to the development of new therapies as well as the advancement of existing ones for cardiac arrhythmias and pump dysfunction. Reviewed are cardiac modeling efforts aimed at advancing and optimizing existent therapies for cardiac disease (defibrillation, ablation of ventricular tachycardia, and cardiac resynchronization therapy) and at suggesting novel treatments, including novel molecular targets, as well as efforts to use cardiac models in stratification of patients likely to benefit from a given therapy, and the use of models in diagnostic procedures. Read More

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http://dx.doi.org/10.5402/2012/269680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505657PMC
December 2012
4 Reads

Glycemic Control during Coronary Artery Bypass Graft Surgery.

Authors:
Harold L Lazar

ISRN Cardiol 2012 14;2012:292490. Epub 2012 Nov 14.

Department of Cardiothoracic Surgery, The Boston Medical Center and The Boston University School of Medicine, 88 East Newton Street, Boston, MA 02118, USA.

Hyperglycemia, which occurs in the perioperative period during cardiac surgery, has been shown to be associated with increased morbidity and mortality. The management of perioperative hyperglycemia during coronary artery bypass graft surgery and all cardiac surgical procedures has been the focus of intensive study in recent years. This report will paper the pathophysiology responsible for the detrimental effects of perioperative hyperglycemia during cardiac surgery, show how continuous insulin infusions in the perioperative period have improved outcomes, and discuss the results of trials designed to determine what level of a glycemic control is necessary to achieve optimal clinical outcomes. Read More

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http://dx.doi.org/10.5402/2012/292490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504366PMC
December 2012
3 Reads

Carotid artery disease and stroke: assessing risk with vessel wall MRI.

Authors:
William S Kerwin

ISRN Cardiol 2012 14;2012:180710. Epub 2012 Nov 14.

Department of Radiology, University of Washington, Seattle, WA 98109, USA ; VPDiagnostics Incorporation, Seattle, WA 98101, USA.

Although MRI is widely used to diagnose stenotic carotid arteries, it also detects characteristics of the atherosclerotic plaque itself, including its size, composition, and activity. These features are emerging as additional risk factors for stroke that can be feasibly acquired clinically. This paper summarizes the state of evidence for a clinical role for MRI of carotid atherosclerosis. Read More

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http://dx.doi.org/10.5402/2012/180710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504380PMC
December 2012
42 Reads

Physical activity, health benefits, and mortality risk.

Authors:
Peter Kokkinos

ISRN Cardiol 2012 30;2012:718789. Epub 2012 Oct 30.

Cardiology Department, Veterans Affairs Medical Center, 50 Irving Street NW, Washington, DC 20422, USA ; Division of Cardiology, Department of Medicine, Georgetown University, 4000 Reservoir Road NW, Washington, DC 20057-2197, USA ; Physical Therapy and Health Care Services, George Washington University, 2121 I Street, Washington, DC 20052, USA.

A plethora of epidemiologic evidence from large studies supports unequivocally an inverse, independent, and graded association between volume of physical activity, health, and cardiovascular and overall mortality. This association is evident in apparently healthy individuals, patients with hypertension, type 2 diabetes mellitus, and cardiovascular disease, regardless of body weight. Moreover, the degree of risk associated with physical inactivity is similar to, and in some cases even stronger than, the more traditional cardiovascular risk factors. Read More

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http://dx.doi.org/10.5402/2012/718789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501820PMC
December 2012
4 Reads

Left ventricular hypertrophy is associated with diastolic filling alterations in normotensive offspring of hypertensive nigerians.

ISRN Cardiol 2012 30;2012:256738. Epub 2012 Oct 30.

Department of Medicine, University of Ilorin, PMB 1515, Ilorin, Nigeria.

Contribution of left ventricular diastolic dysfunction to adverse events in patients with cardiovascular diseases is increasingly being recognized and individuals with pedigree for hypertension are thought to exhibit anatomic and or functional changes in their left ventricle before they become hypertensive. This study aimed at characterizing left ventricular diastolic function in normotensive offspring of hypertensive Nigerians. Sixty-five offspring of hypertensive parents aged 15-25 years (subjects) with 65-age and sex-matched offspring of normotensive parents (controls) were studied for early makers of hypertensive cardiovascular disease using Doppler echocardiogram. Read More

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http://dx.doi.org/10.5402/2012/256738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501814PMC
November 2012
3 Reads

Insights into the pathogenesis of takotsubo syndrome, which with persuasive reasons should be regarded as an acute cardiac sympathetic disease entity.

Authors:
Shams Y-Hassan

ISRN Cardiol 2012 15;2012:593735. Epub 2012 Oct 15.

Department of Cardiology, Karolinska Institute, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.

The pathogenesis of takotsubo syndrome (TS) has not been established yet. The literature data dealing with the pathogenesis of TS are abundant but scattered among different medical specialities. Subarachnoid hemorrhage and other acute intracranial diseases and injuries are among the important and currently well-recognized trigger factors for TS. Read More

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http://dx.doi.org/10.5402/2012/593735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478743PMC
November 2012
5 Reads

The sweet spot: continued search for the glycemic threshold for macrovascular disease-a retrospective single center experience.

ISRN Cardiol 2012 14;2012:874706. Epub 2012 Oct 14.

Department of Cardiology and Internal Medicine, St. John Hospital and Medical Center, Detroit, MI 48267-3271, USA.

Background. Atherosclerotic cardiovascular disease (ASCVD) is a common complication of diabetes mellitus and impaired fasting glucose (IFG). We hypothesized that the relation of fasting glucose levels to ASCVD is linear, with the prevalence of clinical ASCVD beginning to increase even among individuals currently categorized as normoglycemic. Read More

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http://dx.doi.org/10.5402/2012/874706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477768PMC
October 2012
7 Reads

Clinical evaluation of a mobile heart rhythm telemonitoring system.

ISRN Cardiol 2012 14;2012:192670. Epub 2012 Oct 14.

Clinic of Cardiology, National Cardiology Hospital, 1309 Sofia, Bulgaria.

Purpose. To evaluate the clinical applicability of a telemonitoring system: telemetric system for collection and distant surveillance of medical information (TEMEO). Methods. Read More

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http://dx.doi.org/10.5402/2012/192670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477669PMC
October 2012
2 Reads

Persistent atrial fibrillation is associated with worse prognosis than paroxysmal atrial fibrillation in acute cerebral infarction.

ISRN Cardiol 2012 27;2012:650915. Epub 2012 Sep 27.

Department of Neurology, Haukeland University Hospital, 5021 Bergen, Norway.

Background and Purpose. We hypothesized that patients with persistent atrial fibrillation (AF) suffer from more severe cerebral infarction than patients with paroxysmal AF due to differences in clot structure and volume. Methods. Read More

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http://dx.doi.org/10.5402/2012/650915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465895PMC
October 2012
5 Reads

Effect of staged preconditioning on biochemical markers in the patients undergoing coronary artery bypass grafting.

ISRN Cardiol 2012 2;2012:204624. Epub 2012 Aug 2.

Department of Cardiothoracic, Imam Khomeini Hospital, Ardabil 56197, Iran.

The present study has investigated the effectiveness of staged-preconditioning, in both remote and target organs. After IP the myocardial release of the biochemical markers including, creatine phosphokinase (CPK), cardiac creatine kinase (CK-MB), cardiac troponin T (cTnT) and lactate dehydrogenase (LDH) were evaluated in patients who underwent CABG, with and without staged-preconditioning. Sixty-one patients entered the study; there were 32 patients in the staged-preconditioning group and 29 patients in the control group. Read More

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https://www.hindawi.com/archive/2012/204624/
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http://dx.doi.org/10.5402/2012/204624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417168PMC
October 2012
12 Reads

MMP-2 and sTNF-R1 Variability in Patients with Essential Hypertension: 1-Year Follow-Up Study.

ISRN Cardiol 2012 13;2012:501894. Epub 2012 Sep 13.

Cardiocirculatory Unit, Research Center, Hospital Universitario y Politécnico La Fe, 46009 Valencia, Spain.

The aim of this study is to analyze MMP-2 and sTNF-R1 variability, potent predictors of cardiovascular events, in stable hypertensive patients during a 12-month followup. 234 asymptomatic patients (age 60 ± 13, 136 male) out of 252 patients with essential hypertension were followed up. MMP-2 and sTNF-R1 were measured at baseline and after 12 months (stage I). Read More

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http://dx.doi.org/10.5402/2012/501894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449115PMC
September 2012
12 Reads

Recurrent syncope in patients with carotid sinus hypersensitivity.

ISRN Cardiol 2012 10;2012:216206. Epub 2012 Sep 10.

UO Emergency Medicine and Syncope Unit, Ospedale Santa Maria Nuova-Firenze, Piazza S. Maria Nuova, 1-50131, Florence, Italy ; Cardiology Unit, Electrophysiology and Syncope Unit, Ospedale Santa Maria Nuova-Firenze, Piazza S. Maria Nuova, 1-50131, Florence, Italy.

Syncope recurrence in pacemaker-implanted subjects for the cardio-inhibitory response to sinus carotid massage (SCM) was investigated. The study-hypothesis was that recurrences had significant vasodepressor responses that could justify the loss of consciousness. Forty-six patients were enrolled (16 patients and 30 controls), followed and revaluated after 5-7 years. Read More

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http://dx.doi.org/10.5402/2012/216206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444836PMC
September 2012
3 Reads