Search Our Scientific Publications & Authors

J Gynecol Obstet Hum Reprod 2021 Jun 21:102188. Epub 2021 Jun 21.

APHP, Hôpital Bichat - Claude-Bernard, Department of Obstetrics and Gynaecology, 46 rue Henri-Huchard, 75018, Paris, France.

Objective: To provide guidelines from the French College of Obstetricians and Gynaecologists (CNGOF), based on the best evidence available, concerning the impact of endometrial destruction on bleeding and endometrial cancer risk reduction in patients candidates for operative hysteroscopy.

Methods: Recommendations were made according to AGREE II and the GRADE® (Grading of Recommendations Assessment, Development and Evaluation) systems to determine separately the quality of evidence (QE) and in the level of recommendation.

Results: In a retrospective study comparing the incidence of endometrial cancer in 4 776 patients with menorrhagia treated with endometrial destruction vs 229 945 patients with a medical treatment. Read More

Minim Invasive Ther Allied Technol 2021 Jun 22:1-6. Epub 2021 Jun 22.

Faculty of Medicine, Institute of Obstetrics and Gynecology, University of Debrecen, Debrecen, Hungary.

The extent of the 2020 pandemic not only extends to the infected patients but also to patients who have been waiting for medical procedures. Reevaluation of the healthcare system is important in order to help assist the needs of intensive care units. The urgency of the gynaecological cases should be aligned based on surgical interventions and minimally invasive methods should be preferred. Read More

J Obstet Gynaecol Res 2021 Jun 21. Epub 2021 Jun 21.

Department of Gynecologic Oncology, The First Hospital of Jilin University, Changchun, China.

Aim: To determine whether hysteroscopy (HSC) increases the risk of intraperitoneal dissemination in endometrial cancer patients.

Methods: We conducted a comprehensive review of multiple databases. Quality assessments of eligible studies were performed using the Newcastle-Ottawa and Jadad scales. Read More

Am J Transl Res 2021 15;13(5):4500-4509. Epub 2021 May 15.

Obstetrics and Gynecology Hospital of Fudan University Shanghai, China.

Objective: In sonography, homogeneous endometrium is defined as uniform endometrial echogenicity and heterogeneous, asymmetrical or cystic endometrium is defined as non-uniform. However, the relationship between the non-uniform endometrial echogenicity and the presence or absence of pathology is not known. A retrospective study of the patients with ultrasound non-uniform endometrium who underwent hysteroscopy-directed biopsy was performed to explore its clinical meaning in the diagnosis of endometrial lesions. Read More

Curr Opin Obstet Gynecol 2021 Jun 18. Epub 2021 Jun 18.

Department of Obstetrics and Gynecology, Brigham and Women's Hospital/Massachusetts General Hospital, Boston Center for Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Newton-Wellesley Hospital, Newton Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Purpose Of Review: Retained products of conception (POC) may occur independently or as a consequence of placenta accreta spectrum (PAS). Managing these conditions depends on the clinical scenario, and in some cases, can involve the use of minimally invasive techniques. This review presents the role of hysteroscopy and laparoscopy in the treatment of retained POC and the adherent placenta. Read More

Sci Rep 2021 Jun 18;11(1):12887. Epub 2021 Jun 18.

Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China.

Recently, few noninvasive methods have been reported to evaluate endometrial fibrosis. Our study was to investigate the feasibility of intravoxel incoherent motion (IVIM) MR imaging in the detection of endometrial fibrosis in patients with intrauterine injury. 30 patients with hysteroscopy-confirmed endometrial fibrosis and 28 healthy women were enrolled to undergo MR examination including the IVIM sequence. Read More

BMC Anesthesiol 2021 Jun 18;21(1):173. Epub 2021 Jun 18.

Department of Anaesthesiology, Mengcheng County No. 1 People's Hospital, Mengcheng, 233500, Anhui Province, P. R. China.

Eur J Obstet Gynecol Reprod Biol 2021 May 25;263:1-6. Epub 2021 May 25.

Department of Obstetrics and Gynecology, Maastricht University Medical Centre+, P. Debyelaan 25, 6229 HX, Maastricht, the Netherlands. Electronic address:

Objective: To analyze perioperative findings and complications in surgical removal of Essure® microinserts.

Study Design: A prospective cohort study of 274 patients who underwent surgical removal of Essure® microinserts. Outcomes of the surgical procedures and complications were entered into a digital case report form (CRF) by the surgeon and registered in an online database. Read More

Fertil Steril 2021 Jun 8. Epub 2021 Jun 8.

Reproductive Biology Associates, Atlanta, Georgia.

Objective: To illustrate a novel surgical management technique for interstitial ectopic pregnancies (IP).

Design: Video description of the case, demonstration of the surgical technique, reevaluation at the 6-week postoperative follow-up, and review of the advantages of this surgical technique for IP.

Setting: Tertiary referral center. Read More

Acta Med Litu 2020 21;27(2):84-89. Epub 2020 Dec 21.

Department of Obstetrics and Gynecology, General and Teaching Hospital Celje, Slovenia.

Unicornuate uterus with non-communicating rudimentary horn is a type of congenital uterine abnormality that occurs as a consequence of the arrested development of one of the two Müllerian ducts. Patients with unicornuate uterus have increased incidence of obstetric and gynaecological complications. We present a report of a clinical case of a 28-years-old female, who was referred to the hospital for evaluation of her infertility. Read More

J Gynecol Obstet Hum Reprod 2021 Jun 7:102182. Epub 2021 Jun 7.

Professor in Obstetrics and Gynaecology, Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Greece.

Purpose: To evaluate the proposed criteria in a large sample and in additional subgroups in order to test the validity of the hysteroscopic features widely-accepted as suggestive of CE METHOD(S): All patients (n: 2675) underwent outpatient hysteroscopy, with the vaginoscopic approach technique. Hysteroscopic features such as, stromal oedema, diffuse or focal hyperaemia, "strawberry aspect", micropolyposis and endometrial polyps, are often indicate the presence of chronic endometritis. All hysteroscopic features, alone and in combination were applied in 7 (seven) different subgroups of the sample: total sample, women in reproductive age, women with infertility issues/IVF screening, women with history of recurrent miscarriages, menopausal women, and women with hysteroscopic indication of Abnormal Uterine Bleeding (AUB) in women of reproductive age and postmenopausal bleeding (PMB). Read More

J Obstet Gynaecol Can 2021 Jun 5. Epub 2021 Jun 5.

Department of Obstetrics and Gynecology, Surgical Endoscopic Unit. Hospital Universitari Son Llàtzer, Palma Spain.

Colouterine fistula associated with the use of an intrauterine device (IUD) is extremely rare. Clinical presentation may vary; however, to our knowledge, only 1 paper has previously reported menochezia as the main symptom of an utero-intestinal fistula as a complication of IUD use. Surgery is generally needed for definitive resolution of the fistula. Read More

J Minim Invasive Gynecol 2021 Jun 2. Epub 2021 Jun 2.

Birmingham Women's Hospital, Birmingham, UK.

Objective: To identify technologies associated with the least operative pain in women undergoing operative office hysteroscopic procedures.

Data Sources: MEDLINE, EMBASE, CINAHL and CENTRAL were searched until January 2021 using a combination of keywords "hysteroscop*", "endometrial ablation", "outpatient", "ambulatory", "office" and associated MeSH headings.

Methods Of Study Selection: Randomized controlled trials (RCTs) evaluating the effect of hysteroscopic devices on pain experienced by women undergoing operative office hysteroscopy were included. Read More

Ann Saudi Med 2021 May-Jun;41(3):135-140. Epub 2021 Jun 1.

From the Department of Obstetrics and Gynecology, Nigde Omer Halisdemir University, Merkez Nigde, Turkey.

Background: Abnormal uterine bleeding (AUB) affects approximately 14% to 25% of women of reproductive age. The most common use of office hysteroscopy is to evaluate pathologies related to AUB and reproductive health, but office hysteroscopy can also be used for the diagnosis and treatment of other intrauterine pathologies.

Objective: Investigate the effects of the temperature of the distension fluid on pain severity in patients undergoing diagnostic office hysteroscopy due to AUB. Read More

J Hum Reprod Sci 2021 Jan-Mar;14(1):94-96. Epub 2021 Mar 30.

Department of Reproductive Medicine, Nova IVF Fertility, Ahmedabad, Gujarat, India.

Improvement in cancer treatments has allowed more women to plan a pregnancy once the disease is cured. The effects of chemotherapy on ovaries are well proven but those on the uterus, especially the endometrium and embryo implantation are still unknown. Usage of newer tyrosine kinase inhibitors such as nilotinib has revolutionized the management of leukemias. Read More

J Hum Reprod Sci 2021 Jan-Mar;14(1):61-67. Epub 2021 Mar 30.

Department of Obstetrics and Gynaecology, AIIMS, New Delhi, India.

Context: Hysteroscopic metroplasty (HM) is the gold standard treatment for women with septate uterus with recurrent pregnancy loss. Miniresectoscope requires less cervical dilatation as compared to conventional resectoscope. Very few studies are available in the literature on use of miniresectoscope for operative purpose. Read More

Turk J Obstet Gynecol 2021 06;18(2):151-158

Sebasticook Valley Hospital, Clinic of Internal Medicine, Pittsfield, Maine, USA

Office hysteroscopy (OH) is a common procedure in gynecology. Pain is the most frequently reported problem in OH. In this study, we aimed to investigate the role of tramadol administration in relieving pain in women undergoing OH. Read More

J Turk Ger Gynecol Assoc 2021 Jun 4. Epub 2021 Jun 4.

Department of Obstetrics and Gynecology, University Hospitals Schleswig-Holstein, Campus Kiel, Kiel, Germany.

Modern surgical technologies allow gynecologists to treat most submucosal myomas by some form of resection hysteroscopically. What appears on imaging or direct visualization to be a submucosal myoma can be a single tumor, or may represent multiple smaller myomas appearing as one, compacted together in a typical pseudo capsule. During myoma resection, the effect of the distending media can be different depending on the morphology of the myomas. Read More

Int J Gen Med 2021 26;14:2087-2094. Epub 2021 May 26.

Department of Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, 361000, People's Republic of China.

Purpose: This study aimed to investigate the clinical efficacy of temporary ligation of the bilateral uterine arteries during laparoscopy combined with hysteroscopy in the treatment of caesarean scar pregnancy (CSP).

Patients And Methods: This study was a retrospective analysis of 83 patients who had initially undergone laparoscopy combined with hysteroscopy for CSP between 2012 and 2018 at Xiamen Women and Children's Hospital. Patients were assigned to the ligation group or the no ligation group according to whether they underwent temporary ligation of the bilateral uterine arteries. Read More

Afr J Reprod Health 2020 Jun;24(2):123-128

Assisted Reproduction Unit, Gynescope Specialist Hospital: 22/24 Gynescope Drive Port Harcourt, Rivers State.

The effect of endometrial thickness on in vitro fertilization (IVF) outcome is still a subject of debate. It is unclear why a thin endometrium reduces IVF success rates. Our objective was to analyze the hysteroscopic findings in women scheduled for IVF who had an endometrial thickness less than 7 mm. Read More

J Clin Med 2021 May 29;10(11). Epub 2021 May 29.

Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.

A retrospective cohort study of the concordance between the magnetic resonance imaging (MRI) diagnosis and final diagnosis in patients with Müllerian duct anomalies (MDAs) was conducted, and diagnostic clues were suggested. A total of 463 cases of young women who underwent pelvic MRIs from January 1995 to February 2019 at Seoul Asan Medical Center were reviewed. Interventions consisted of clinical examinations, abdominal or transvaginal/rectal ultrasound, MRI, and operative procedures, including hysteroscopy and laparoscopy. Read More

J Clin Med 2021 May 17;10(10). Epub 2021 May 17.

Assisted Reproduction Unit, Second Department of Obstetrics and Gynecology, "Aretaieion Hospital", Medical School, National and Kapodistrian University of Athens, Vas. Sofias 76, 11528 Athens, Greece.

(1) Background: Recurrent implantation failure (RIF) after IVF remains a challenging topic for fertility specialists and a frustrating reality for patients with infertility. Various approaches have been investigated and applied towards the improvement of clinical outcomes. Through a nonrandomized clinical trial, we evaluated the effect of the combination of hysteroscopic endometrial injury and the freeze-all technique on pregnancy parameters in a cohort of RIF patients; (2) Methods: The study group comprised of 30 patients with RIF that underwent a hysteroscopic endometrial injury prior to a frozen embryo transfer cycle; another 30 patients with RIF, comprising the control group, underwent a standard frozen cycle with no adjuvant treatment before. Read More

Fertil Steril 2021 May 27. Epub 2021 May 27.

Department of Gynecology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China. Electronic address:

Objective: To introduce a special case of endometrial cavity fluid (ECF), highlighting the application of hysteroscopy and laparoscopic surgical techniques in the treatment of cervical sinus tract.

Design: Narrated video featuring the diagnosis and surgical management of a case of recurrent ECF. Informed consent was obtained from the patient, and approval was granted by the ethics committee of the First Affiliated Hospital of the Wenzhou Medical University. Read More

J Minim Invasive Gynecol 2021 May 27. Epub 2021 May 27.

Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Alexandra Hospital, Greece.

Gynecol Obstet Fertil Senol 2021 May 26. Epub 2021 May 26.

AP-HP, GHU-Sud, CHU Bicêtre, Service Gynécologie Obstétrique, 78, rue du Général Leclerc, 94270 Le Kremlin Bicêtre, France; Faculté de Médecine Paris-Sud Saclay, 63, rue Gabriel Péri, 94270 Le Kremlin Bicêtre, France; Université Paris-Saclay, UVSQ, Inserm, CESP, 94807 Villejuif, France. Electronic address:

Synechiae are intrauterine adhesions that affect the fertility of women. They are most often of post-traumatic origin. The management of pregnancy abortions in the first trimester and post-delivery retention are the main contributing factors. Read More

Reprod Health 2021 May 28;18(1):109. Epub 2021 May 28.

School of Medicine, The University of Jordan, Amman, Jordan.

Background: Pelvic inflammatory disease (PID) is the inflammation of the adnexa of the uterus, that mainly manifests in a subclinical/chronic context and goes largely underreported. However, it poses a major threat to women's health, as it is responsible for infertility and ectopic pregnancies, as well as chronic pelvic pain. Previous studies in Jordan have not reported PID, attributed mainly to the social structure of the country which largely represents a sexually conservative population. Read More

J Obstet Gynaecol Can 2021 May 25. Epub 2021 May 25.

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, McGill University, Montréal Quebec H3A 0G4, Canada.

Objective: To determine feasibility and accuracy of post-hysteroscopic transvaginal ultrasonography (TVUS) measurement of pelvic fluid accumulation as a screening method for tubal patency (TP).

Methods: We conducted a retrospective cohort study of 85 patients who underwent uterine cavity assessment by office hysteroscopy at our university-affiliated fertility centre from November 2019 to October 2020. During the study period, two-dimensional (2D) TVUS was performed pre- and post-hysteroscopy to evaluate TP. Read More

J Matern Fetal Neonatal Med 2021 May 27:1-9. Epub 2021 May 27.

Department of Obstetrics and Gynecology, Amsterdam UMC, location VU University Medical Center, Amsterdam, The Netherlands.

Background: Moderate to severe intrauterine adhesions (IUAs) may greatly impact fertility, predisposing to pregnancy and obstetric complications. The impact of mild IUAs on reproductive performance remains unclear. A systematic review and meta-analysis was performed to examine the long-term reproductive outcomes in women with hysteroscopic identified and treated mild IUAs mild intrauterine adhesions (IUAs). Read More

Gynecol Minim Invasive Ther 2021 Apr-Jun;10(2):121-123. Epub 2021 Apr 30.

Department of Obstetrics and Gynecology, University of Health Sciences Turkey, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Retained intrauterine objects are rare causes of persistent vaginal discharge and pelvic inflammatory disease. Hysteroscopy is a minimally invasive technique used for removing these materials. A 47-year-old female who had recurrent vaginal discharge was admitted to our emergency department with pelvic pain. Read More

Front Endocrinol (Lausanne) 2021 10;12:659647. Epub 2021 May 10.

Department of Obstetrics and Gynaecology, The University of Auckland, Auckland, New Zealand.

Objective: The outcomes of subsequent pregnancies and fertility in women with a history of caesarean scar pregnancy have not been well described. In this study, we followed up 149 women with a history of caesarean scar pregnancy and analysed the effect on their fertility.

Methods: 149 women with a history of caesarean scar pregnancy were followed up for five years. Read More