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Fertil Steril 2020 Jul;114(1):187-188

Instituto de Salud de la Mujer José Botella Llusiá, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain.

Objective: To study differences between robotic and laparoscopic approach in Essure device removal.

Design: Demonstration video of two different surgical approaches.

Setting: Clinico San Carlos University Hospital in Madrid, Spain. Read More

Ultrasound Obstet Gynecol 2020 Jul 4. Epub 2020 Jul 4.

Institute for Women's Health, University College London Hospitals, London, UK.

Objectives: The objective of our study was to assess the inter-rater agreement and reliability of using subjective pattern recognition to diagnose endometrial cancer on ultrasound in women with postmenopausal bleeding.

Methods: This was a prospective cross-sectional study at a gynaecological rapid access clinic, between Oct 2016 - Dec 2017, where consecutive women with postmenopausal bleeding and endometrial thickness of ≥4.5mm on transvaginal ultrasound scan were included. Read More

BJOG 2020 Jul 1. Epub 2020 Jul 1.

Birmingham Women's Hospital, Edgbaston, Birmingham, B15 2TG, United Kingdom.

We are all likely to need a blood test, a biopsy or wind up on the wrong end of an endoscope. We know that the experience is not going to be pleasant. Many of us will revert to techniques to divert attention away from painful stimuli, such as counting forwards or backwards in our heads, deep breathing, imagining tranquil places or listening to music. Read More

Cochrane Database Syst Rev 2020 Jul 1;7:CD011174. Epub 2020 Jul 1.

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.

Background: Non-tubal ectopic pregnancy is the implantation of an embryo at a site lying outside the uterine cavity or fallopian tubes. Sites include a caesarean scar, the cornua uteri, the ovary, the cervix, and the abdomen. There has been an increasing trend in the occurrence of these rare conditions, especially caesarean scar pregnancy (CSP). Read More

Rev Bras Ginecol Obstet 2020 Jun 30;42(6):325-332. Epub 2020 Jun 30.

Department of General Surgery ad Specialty, Universidade Federal Fluminense, Niterói, RJ, Brazil.

Objective:  To evaluate the insertion of the hysteroscopic intratubal sterilization device for female sterilization concerning the technique and the feasibility.

Methods:  Retrospective study with data collection of medical records of 904 patients who underwent device insertion between January and September 2016 in a public hospital in Rio de Janeiro (Brazil) with data analysis and descriptive statistics.

Results:  In 85. Read More

J Minim Invasive Gynecol 2020 Jun 27. Epub 2020 Jun 27.

The Advanced Gynecologic Institute, Park Ridge, IL. Electronic address:

Objective: To demonstrate our technique for robotic assisted laparoscopic ectopic pregnancy excision and concomitant scar revision.

Design: We present a stepwise narrated demonstration of our primary laparoscopic technique.

Setting: Although cesarean scar pregnancy is rare, it leads to life-threatening complications and often emergent hysterectomy. Read More

Neurosci Lett 2020 Jun 27:135215. Epub 2020 Jun 27.

Department of Gynaecology and Obstetrics, Maternal and Child Health Hospital of Cangxi, Guangyuan City, 628400, Sichuan Province, China. Electronic address:

To explore the clinical significance of pre-diagnostic curettage under hysteroscopy in the diagnosis of endometrial carcinoma, evaluate the clinical staging, and optimize the function of hysteroscopy computer information system after artificial intelligence algorithm optimization, 200 patients who were diagnosed as endometrial carcinoma in our hospital between June 2015 and July 2019 were included and divided into a hysteroscopy segmental curettage group (101 patients) and a segmented curettage group (99 patients). For patients in both groups, the histopathological examination was performed, and the abdominal lavage fluid was collected. The artificial intelligence algorithm was utilized to optimize the hysteroscopy computer information system. Read More

Acta Clin Croat 2019 Dec;58(4):627-631

1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.

The aim of our study was to determine the prevalence of endometrial premalignant and malignant lesions in women undergoing hysteroscopy and to identify anthropologic factors related to the presence of malignancy. Data on 3470 women with submucosal myomas or endometrial polyps suspected on ultrasound were retrospectively analyzed. Hysteroscopy was performed in all these women in order to make a more precise diagnosis. Read More

Med Sci Monit 2020 Jun 29;26:e924076. Epub 2020 Jun 29.

Department of Obstetrics and Gynecology, Ningbo Women's and Children's Hospital, Ningbo, Zhejiang, China (mainland).

BACKGROUND With the changes in China's family planning policy, the incidence of cesarean scar pregnancy (CSP) significantly increased in recent years. The present study aimed to investigate the clinical efficacy of combined hysteroscopic and laparoscopic surgery and reversible ligation of the uterine artery for cesarean scar excision and repair in patients with type II and III CSP. MATERIAL AND METHODS This was a retrospective study of 173 patients with type II and III CSP. Read More

Eur J Obstet Gynecol Reprod Biol 2020 Jun 17;252:112-117. Epub 2020 Jun 17.

The Fertility Clinic, Hvidovre Hospital, Copenhagen University Hospital, Kettegaard Allé 30, 2650, Hvidovre, Denmark; The Fertility Clinic, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark.

Objective: Endometrial scratch injury (ESI) has been proposed to improve endometrial receptivity and thereby increase implantation rates in assisted reproductive technology (ART) treatment. ESI has been widely incorporated into clinical practice despite inconclusive evidence of its effect on reproductive outcomes. We aimed to assess pregnancy and live birth rates in subfertile women receiving ESI before IVF treatment in comparison to controls. Read More

Medicine (Baltimore) 2020 Jun;99(26):e20491

Clinic of Obstetrics and Gynecology, DINOGMI, IRCCS San Martino Hospital, University of Genova, Genova (GE), Italy.

Background: Atypical polypoid adenomyoma (APA) is a rare uterine tumor typically found in fertile age and associated with infertility. Among young nullipara women, conservative treatment is proposed despite the high recurrence rate and the association with endometrial cancer.Our aim was to assess the risk of recurrence with different conservative treatments in fertile ages and the prevalence of malignant or pre-malignant associated lesions to better address an adequate patient counselling when treatment modalities are discussed. Read More

Eur J Obstet Gynecol Reprod Biol 2020 Jun 8;252:82-86. Epub 2020 Jun 8.

Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China. Electronic address:

Objective: To compare the safety and clinical effectiveness of high-intensity focused ultrasound (HIFU) and uterine artery embolization (UAE) for retained placenta accreta.

Study Design: A retrospective analysis was performed on women who underwent HIFU or UAE followed by hysteroscopic resection for retained placenta accreta from January 2015 to December 2019 at the Third Xiangya Hospital of Central South University.

Results: A total of 63 and 31 patients who underwent HIFU and UAE followed by hysteroscopic resection, respectively, were analyzed. Read More

J Obstet Gynaecol Res 2020 Jun 23. Epub 2020 Jun 23.

Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece.

The role of hysteroscopy in cases of chronic or subclinical endometritis remains uncertain. Reevaluating the clinical relevance of diagnostic hysteroscopic in these cases will improve the level of case in women's health worldwide. The objective of this systematic review was to assess the suitability of hysteroscopy in detecting and diagnosing female patients with chronic or subclinical endometritis, as a first-line diagnostic tool. Read More

Female Pelvic Med Reconstr Surg 2020 Jun 22. Epub 2020 Jun 22.

Providence Saint John's Health Center, Santa Monica, CA.

Objective: The aim of the study was to determine whether a hysterectomy at the time of native tissue pelvic organ prolapse repair is cost-effective for the prevention of endometrial cancer.

Methods: We created a decision analysis model using TreeAge Pro. We modeled prolapse recurrence after total vaginal hysterectomy with uterosacral ligament suspension (TVH-USLS) versus sacrospinous ligament fixation hysteropexy (SSLF-HPXY). Read More

BJOG 2020 Jun 23. Epub 2020 Jun 23.

School of Psychology, University of Leeds, UK.

Objective: To evaluate the effectiveness of virtual reality as a distraction technique in the management of acute pain and anxiety during outpatient hysteroscopy.

Design: Parallel group, prospective randomised controlled trial.

Setting: UK University Hospital. Read More

Eur J Obstet Gynecol Reprod Biol 2020 Jun 2;252:70-81. Epub 2020 Jun 2.

Birmingham Women's Hospital, Birmingham Women's and Children's NHS Foundation Trust, Mindelsohn Way, Birmingham, B15 2TG, UK.

Objective: To compare the effects of different types and routes of administration of local anaesthetic for pain control during and after office hysteroscopy.

Methods: Medline, Embase, CINAHL and the Cochrane library were searched from inception until October 2019, in order to perform a systematic review and meta-analysis of all randomised controlled trials investigating the use of a local anaesthetic compared to a control, for pain relief in women undergoing diagnostic or operative office hysteroscopy. Average pain scores and data regarding side-effects, feasibility, complications, acceptability and satisfaction were collected. Read More

Jpn J Clin Oncol 2020 Jun 22. Epub 2020 Jun 22.

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Background: To date, only few large studies are available concerning the safety and diagnostic concordance rates of outpatient flexible hysteroscopy. In our institution, outpatient hysteroscopy has been routinely and educationally applied Kosuke Tsuji to intrauterine lesions; thus, we retrospectively investigated the institution's outpatient flexible hysteroscopy cases.

Methods: A total of 1591 cases of outpatient flexible hysteroscopy conducted at our institution in 2012-2016 were retrospectively analyzed in terms of their clinical background, complications and diagnostic concordance rates. Read More

Rev Bras Ginecol Obstet 2020 Jun 19. Epub 2020 Jun 19.

Ginecology Department, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Objective:  Gonadotropin-releasing hormone analogues (GnRH-a) have been used preoperatively before hysteroscopic myomectomy to decrease the size and vascularization of the myomas, but evidence to support this practice is weak. Our objective was to analyze the use of GnRH-a in the reduction of submucous fibroid as a facilitator for surgical hysteroscopy from published clinical trials.

Data Sources:  Studies from electronic databases (Pubmed, Scielo, EMBASE, Scopus, PROSPERO), published between 1980 and December 2018. Read More

J Obstet Gynaecol Res 2020 Jun 17. Epub 2020 Jun 17.

Department of Obstetrics and Gynecology, Clinico University Hospital Lozano Blesa, University of Zaragoza, Zaragoza, Spain.

Uterine perforation is a potential complication of intrauterine procedures that can be associated with vascular or visceral injury. We report the case of a 35-year-old woman diagnosed with omentum incarceration, secondary to a uterine perforation, during a dilatation and curettage. This rare complication was successfully managed by release of incarcerated omentum hysteroscopically. Read More

J Int Med Res 2020 Jun;48(6):300060520931319

Department of Gynaecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Cases of urogenital sinus malformation with a huge calculus are complex and rare. Improper nursing care of these cases can lead to a series of problems. We report here a 23-year-old married woman who was admitted to hospital because of primary amenorrhea and failed sexual intercourse for 5 years. Read More

Oxf Med Case Reports 2020 Jun 13;2020(6):omaa038. Epub 2020 Jun 13.

Department of Pathology, Faculty of Medicine, Damascus University, Damascus, Syria.

Recurrent pregnancy loss (RPL) is a common disease, which presents as two, three or more failed pregnancies. It is attributed to many risk factors, yet half of the cases are idiopathic. In this report, we present a case of a 44-year-old woman with a complaint of secondary infertility for 10 years and a history of three spontaneous abortions. Read More

Obstet Gynecol Sci 2020 06 19. Epub 2020 Jun 19.

Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

Objective: The aim of the present study was to compare the efficacy of vaginal isoniazid (isonicotinic acid hydrazide [INH]) and vaginal misoprostol in cervical ripening before hysteroscopic surgery.

Methods: This randomized controlled trial included patients scheduled for hysteroscopic surgery during April 2016 and June 2017. The inclusion criteria were as follows: postmenopausal women or those at premenopausal age who had not had a vaginal delivery and candidate for diagnostic or operative hysteroscopy with closed cervix before intervention. Read More

Medicina (Kaunas) 2020 Jun 12;56(6). Epub 2020 Jun 12.

Institute for Maternal and Child Health IRCCS "Burlo Garofolo", 34100 Trieste, Italy.

Cervical pregnancy (CP) is a rare form of ectopic pregnancy (EP) in which the embryo implants and grows inside the endocervical canal. Early diagnosis is essential in order to allow conservative medical and surgical treatments. Although many treatment approaches are disponible, the most effective is still unclear. Read More

Int J Gynaecol Obstet 2020 Jun 15. Epub 2020 Jun 15.

Department of Gynecology, Maternal, Child Health Hospital of Hubei Province, Wuhan, Hubei, 430070, China.

Robert's uterus and bicornuate uterus are two different kinds of congenital uterine malformation. In the present study, the authors report a rare case of a 16-year-old girl diagnosed with hybrid Robert's uterus and bicornuate uterus, and unique ipsilateral renal agenesis. The authors performed a minimally invasive surgical procedure to obtain asymmetric uterine septum resection by combined hysteroscopy-laparoscopy. Read More

J Minim Invasive Gynecol 2020 Jun 12. Epub 2020 Jun 12.

Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN.

Study Objective: To trial the use of a novel endoscopic robot that functions using concentric tube robots enabling two-handed surgery in small spaces in a bioengineering laboratory. This was a feasibility study of the endoscopic robot for hysteroscopic applications, including removal of a simulated endometrial polyp. The endoscopic robot was successfully used to resect a simulated endometrial polyp from a porcine uterine tissue model in a fluid environment. Read More

Int J Gynaecol Obstet 2020 Jun 13. Epub 2020 Jun 13.

University of Debrecen, Faculty of Medicine, Department of Obstetrics and Gynecology, Debrecen, Hungary.

COVID-19 was was declared a pandemic by the World Health Organization (WHO) during its 51st situation report on March 11, 2020.[1] One purpose of the report was to advise restructuring of healthcare services by limiting them to urgent or emergent cases in order to reduce pressure on the intensive care units (ICU) of hospitals treating COVID-19-positive patients. Read More

Fertil Steril 2020 Jul 10;114(1):175-184. Epub 2020 Jun 10.

Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota; Division of Reproductive Endocrinology and Infertility, Mayo Clinic, Rochester, Minnesota; Division of Minimally Invasive Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota.

Objective: To evaluate blood transfusion risks and the associated 30-day postoperative morbidity after myomectomy.

Design: Retrospective cohort study.

Setting: Not applicable. Read More

Ceska Gynekol 2020 ;85(2):84-93

Objective: The aim of our study was to analyze a group of patients referred for endometrial biopsy. To evaluate the ultrasound finding of hyperplasia/polyp, the symptomatology of patients related to the result of definitive histology, to determine the severity of individual variables in connection with the detection of precancerosis/cancer. Due to the complexity of information identify women who are suitable for conservative approach. Read More

J Minim Invasive Gynecol 2020 Jun 8. Epub 2020 Jun 8.

University of Miami. Miller School of Medicine. Miami. USA. Electronic address:

Study Objective: Hysteroscopy is considered the gold standard technique for the diagnosis and management of intrauterine pathology allowing to "see and treat" in one session if desired (1-3). Pain and inability to enter the uterine cavity are the most common limitations of hysteroscopy, especially when performed in the office setting (4-7). Cervical stenosis is a common hysteroscopic finding frequently encountered in postmenopausal women, especially in patients with history of cervical procedures such as cone biopsy. Read More

Mol Cell Endocrinol 2020 Jun 7;514:110887. Epub 2020 Jun 7.

Department of Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, PR China. Electronic address:

Long noncoding RNAs (lncRNAs) modulate endometriosis. The current study investigated the mechanisms and effects of SNHG4 on endometriosis. The qRT-PCR was conducted to examine the miR-148a-3p and SNHG4 expressions in endometriosis tissues. Read More

Gynecol Obstet Fertil Senol 2020 Jun 6. Epub 2020 Jun 6.

Département de gynécologie, hôpital Femme-Mère-Enfant, HFME, hospices civils de Lyon, 59, boulevard Pinel, 69677 Bron, France.

Climacteric 2020 Jun 10:1-4. Epub 2020 Jun 10.

Gynaecological Endoscopy, Rosewalk Hospital, New Delhi, India.

Hysteroscopy is the gold standard for evaluating the uterine cavity, diagnosing intrauterine pathology, and operative intervention for some causes of abnormal uterine bleeding. The American College of Obstetricians and Gynecologists concluded that, when the endometrium measures ≤4 mm with transvaginal ultrasonography, the likelihood that bleeding is secondary to endometrial carcinoma is less than 1% (negative predictive value 99%), and endometrial biopsy is not recommended. Endometrial sampling in this clinical scenario will likely result in insufficient tissue for evaluation and it is reasonable to consider initial management for atrophy. Read More

Mil Med 2020 Jun 9. Epub 2020 Jun 9.

Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue Bethesda, MD 20889.

Introduction: Office hysteroscopy has become a cornerstone of modern gynecologic care through the advent of advanced technology and emphasis on an efficient healthcare system. In 2017, Medicare announced an increase in office hysteroscopy reimbursement by 237%, giving an incentive for gynecologists to move from the operating room into the clinic. The U. Read More

Updates Surg 2020 Jun 8. Epub 2020 Jun 8.

Department of Obstetrics and Gynecology, "Filippo Del Ponte" Hospital, University of Insubria, Varese, Italy.

Asherman syndrome (AS) consists of intrauterine adhesions development as a consequence of trauma, radiation, or infection in the endometrium. Clinical symptoms include menstrual alterations, infertility, and pregnancy complications, such as recurrent pregnancy loss or abnormal placentation. In this article, we performed a narrative review of the literature, searching electronic databases (i. Read More

Eur J Obstet Gynecol Reprod Biol 2020 May 11;251:173-179. Epub 2020 May 11.

Gynecology and Obstetrics, Copenhagen University Hospital, Copenhagen, Denmark.

Objective: To evaluate and compare the diagnostic efficiency of outpatient endometrial sampling (OES) and hysteroscopic resectoscope-directed biopsies (HY) to distinguish between endometrial cancer (EC) and atypical hyperplasia (AH) and to assess tumor type and grade (histotype) in women with EC.

Design: Patients with AH or EC (n = 266) among 1013 patients consecutively referred because of postmenopausal bleeding were included. Identification of EC versus AH, and unfavorable tumor types (endometrioid grade 3 or non-endometrioid tumors) using OES and HY was compared to final histopathology at hysterectomy. Read More

J Minim Invasive Gynecol 2020 Jun 3. Epub 2020 Jun 3.

Obstetrics, Gynecology and Reproductive Science Department. Minimally Invasive Gynecology Unit. University of Miami. Miller School of Medicine. Miami FL, USA. Electronic address:

J Obstet Gynaecol Res 2020 Jun 4. Epub 2020 Jun 4.

The Obstetrics and Gynaecology Clinic Narodni Front, Belgrade, Serbia.

Detectable serum levels of beta subunit of human chorionic gonadotropin (βhCG) in nonpregnant, perimenopausal women bring confusion in both clinician and patient and could lead to unnecessary diagnostic and therapeutic procedures. A 45-year-old woman with the continuous elevation of βhCG underwent hysteroscopy, two laparoscopic surgeries, two explorative uterine cavity curettages and three cycles of cytostatic therapy. No ultrasonographic, macroscopic or histological signs of pregnancy, both uterine and ectopic or gestational trophoblastic disease were found. Read More

Climacteric 2020 Jun 4:1-7. Epub 2020 Jun 4.

Department of Obstetrics and Gynaecology, Mater Clinic, Sydney, Australia.

Endometrial polyps are a common finding, with a prevalence of about 40%, and are usually diagnosed incidentally as most are asymptomatic. Symptomatic polyps usually present with abnormal uterine bleeding and/or sub-fertility. About 25% of polyps resolve spontaneously if managed conservatively. Read More

Eur Rev Med Pharmacol Sci 2020 May;24(10):5217-5222

Woman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche, Ancona, Italy.

Objective: Any diagnostic workup should be based on appropriateness criteria. Diagnostic hysteroscopy is a procedure widely used in endometrial pathology. Its high outpatient feasibility frequently leads to misuse. Read More

Minim Invasive Ther Allied Technol 2020 Jun 3:1-5. Epub 2020 Jun 3.

Department of Gynecologic Oncology, Bakirkoy Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Our objective was to compare the effect of rectal misoprostol (Cytotec) versus rectal hyoscine-n-butyl bromide (Buscopan) on patients undergoing hysteroscopy. We hypothesised that HBB may have a role in cervical priming. This trial was conducted at Bezmialem Vakif University Hospital. Read More

Wideochir Inne Tech Maloinwazyjne 2020 Jun 5;15(2):337-345. Epub 2019 Nov 5.

Department of Gynecology and Oncological Gynecology, Military Institute of Medicine, Warsaw, Poland.

Introduction: Hysteroscopy is the gold standard for diagnosis and treatment of uterine pathologies. The office setting seems to be safe, reducing the anesthesia risks and also decreasing the overall costs of the procedure. Recent literature suggests that hysteroscopy performed without anesthesia may not be as painless as it was previously considered. Read More

Wideochir Inne Tech Maloinwazyjne 2020 Jun 28;15(2):329-336. Epub 2019 Oct 28.

Department of Obstetrics and Gynecology, University of Health Sciences, Faculty of Medicine, Kanuni Sultan Suleyman Hospital, Istanbul, Turkey.

Introduction: Use of multimedia tools has been shown to improve patient comprehension, reduce pre-procedural anxiety, and increase patient satisfaction in various surgical settings.

Aim: To investigate the impact of video-based multimedia information (MMI) on the anxiety levels of patients undergoing office hysteroscopy (OH).

Material And Methods: All consecutive women aged 18-65 years and scheduled for diagnostic OH were enrolled in this prospective randomized study. Read More

BMC Pregnancy Childbirth 2020 May 30;20(1):333. Epub 2020 May 30.

Fetal Medicine Unit - Maternal and Child Health and Development Network (Red SAMID-RD12/0026/0016). Department of Obstetrics and Gynecology. University Hospital 12 de Octubre. 12 de Octubre Research Institute (imas12), Complutense University of Madrid, Madrid, Spain.

Background: The effects of endometrial scratching (ES) on embryo implantation have been studied for many years. Several studies have shown better outcomes when performed on patients undergoing intrauterine insemination and in vitro fertilization (IVF) cycles, but many other reports have not been able to find these differences. As far as cycles with donor eggs are concerned, reported evidence is scarce. Read More

J Pediatr Adolesc Gynecol 2020 May 27. Epub 2020 May 27.

Obstetrics and Gynecology Hospital of Fudan University,Shanghai,China. Electronic address:

Background: Mullerian anomalies (MAs) take many forms of manifestation. The oblique cervical septum with a complete uterine septum (OCSCUS), as a rare form of MA, has never been reported in the literature before.

Case: A 10-year-old female adolescent presented with progressive abdominal pain after the onset of menarche was diagnosed as OCSCUS by MRI and treated with hysteroscopic dissection of the uterine part of the septum. Read More

Reprod Sci 2020 May 28. Epub 2020 May 28.

Fetal Medicine Unit - Maternal and Child Health and Development Network (Red SAMID-RD12/0026/0016), Department of Obstetrics and Gynecology, University Hospital 12 de Octubre, 12 de Octubre Research Institute (imas12), Complutense University of Madrid, Avda. Andalucia s/n, Madrid, Spain.

The potential benefit of endometrial scratching (ES) on embryo implantation is still a controversial subject. At present, the single retrospective study in egg donor IVF cycles concluded that ES has no beneficial effect. Our objective was to determine if there are differences in clinical pregnancy rates (CPR) in egg donor cycles when an ES is performed. Read More

Gynecol Oncol 2020 May 25. Epub 2020 May 25.

Anatomopathology Unit, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Objective: To investigate the diagnostic accuracy of endometrial biopsy performed with hysteroscopic direct visualization using the "grasp technique" for the detection of endometrial carcinoma (EC) histology type and tumor grade.

Methods: A cross-sectional study including the clinical and pathology records of patients with confirmed EC who underwent definitive surgery at University of Naples was performed. The preoperative diagnosis of endometrial tumor type and grade obtained using the hysteroscopy grasp technique was correlated with the final pathology specimens. Read More

Reprod Biomed Online 2020 Jul 14;41(1):62-68. Epub 2020 Mar 14.

Universitair Ziekenhuis Brussel, Centre for Reproductive Medicine, Brussels, Belgium.

Research Question: Endometrial polyps are a frequent finding during fertility treatment. Although up to 27% of small polyps (<10 mm) regress spontaneously, there is clinical benefit to removing a polyp detected before intrauterine insemination (IUI), regardless of size. However, the clinical outcome of IUI following a new suspicion of a polyp during follicle tracking is unknown. Read More

J Clin Pharmacol 2020 May 23. Epub 2020 May 23.

Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

Mental disorders are thought to affect various clinical outcomes during the perioperative period. Among them, anxiety and depression are 2 of the most common types. However, the impacts of anxiety or depression on propofol requirements remain unclear. Read More

Reprod Biomed Online 2020 Jul 28;41(1):55-61. Epub 2020 Apr 28.

Obstetrics and Gynecology Unit, Department of General Surgery and Medical Surgical Specialties, University of Catania, Via Santa Sofia 78, Catania 95123, Italy. Electronic address:

Asherman syndrome is a rare acquired clinical condition resulting in the obliteration of the uterine cavity causedby the presence of partial or complete fibrous intrauterine adhesions involving at least two-thirds of the uterine cavity potentially obstructing the internal cervical orifice. Common reported symptoms of the disease are alterations of the menstrual pattern with decreased menstrual bleeding leading up to amenorrhoea and infertility. Hysteroscopy is currently considered the gold standard diagnostic and therapeutic approach for patients with intrauterine adhesions. Read More

Int J Womens Health 2020 6;12:359-367. Epub 2020 May 6.

Department of Anesthesia, School of Medicine, The University of Jordan, Amman, Jordan.

Objective: The aim of this study was to determine if combining intravenous oxytocin infusion and spinal anesthesia will reduce the amount of glycine absorption in patients undergoing operative hysteroscopy.

Patients And Methods: A prospective controlled study was conducted in premenopausal patients who had hysteroscopic surgery including endometrial resection, endometrial polypectomy, myomectomy resection and uterine septal resection. The effect of combined spinal anesthetic with oxytocin infusion on fluid deficit was studied. Read More