Search Our Scientific Publications & Authors

Cochrane Database Syst Rev 2019 Apr 16;4:CD012856. Epub 2019 Apr 16.

Department of Reproductive Medicine, Christian Medical College, Ida Scudder Road, Vellore, Tamil Nadu, India, 632004.

Background: Screening hysteroscopy in infertile women with unexplained infertility, or prior to intrauterine insemination (IUI) or in vitro fertilisation (IVF) may reveal intrauterine pathology that may not be detected by routine transvaginal ultrasound. Hysteroscopy, whether purely diagnostic or operative may improve reproductive outcomes.

Objectives: To assess the effectiveness and safety of screening hysteroscopy in subfertile women undergoing evaluation for infertility, and subfertile women undergoing IUI or IVF. Read More

Rev Bras Ginecol Obstet 2019 Apr 16. Epub 2019 Apr 16.

Department of Specialized Medicine, Universidade Federal do Piauí, Teresina, PI, Brazil.

Background:  Most endometrial cancers (75%) are diagnosed in early stages (stages I and II), in which abnormal uterine bleeding is the most frequent clinical sign. When the diagnosis is performed in stage IV, the most common sites of metastasis are the lungs, liver and bones. Central nervous system (CNS) metastasis is a rare condition. Read More

Eur J Contracept Reprod Health Care 2019 Apr 15:1-3. Epub 2019 Apr 15.

a Department of Obstetrics and Gynaecology , Kawasaki Municipal Kawasaki Hospital , Kawasaki , Japan.

Objective: We investigated the effectiveness of removing lost intrauterine devices (IUDs) that had been in place for over 10 years, using Lin's biopsy grasper in an office setting.

Methods: This single-centre, retrospective study conducted between March 2006 and June 2018 included 49 women who had had an IUD in place for contraception for more than 10 years and who underwent removal of the lost IUD using Lin's biopsy grasper under transabdominal sonography without use of a tenaculum, anaesthesia and analgesia, after dilation of the cervical os and hysteroscopy.

Results: The women's median age was 52 years (range 34-80 years) and the median duration of insertion was 17 years (range 10-43 years). Read More

Gynecol Endocrinol 2019 Apr 13:1-5. Epub 2019 Apr 13.

b Department of Respiratory Medicine , The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army (Former Lanzhou General Hospital of Lanzhou Military Region) , Lanzhou , China.

Objective: To investigate the MRI manifestations of congenital vaginal atresia, analyze its imaging features, and improve the understanding of the disease.

Methods: MRI findings and clinical data of 12 patients with congenital vaginal atresia confirmed by hysteroscopy and laparoscopic surgery were retrospectively analyzed. Vaginal atresia was classified according to vaginal dysplasia in AFS female genital malformation classification system. Read More

Arch Gynecol Obstet 2019 Apr 11. Epub 2019 Apr 11.

Faculty of Medicine, Institute of Obstetrics and Gynaecology, University of Debrecen, Debrecen, Hungary.

Aim: Our purpose is to investigate if transcervical resection of endometrial polyps improves the fertility in ovulatory infertile women, and whether polyp histology, intrauterine location, and the technique of polypectomy have any influence on the pregnancy rates.

Methods: In this retrospective study, clinical data of 87 ovulatory infertile women who underwent hysteroscopy and polypectomy, and their 12-month follow-up have been analyzed. Subgroups according to the method of polyp removal (resectoscope or curettage), the polyp localization (utero-tubal, anterior, posterior, lateral, multiple) and the histological result were interpreted. Read More

ANZ J Surg 2019 Apr 11. Epub 2019 Apr 11.

Centre for Health Research Illawarra Shoalhaven Population, Australian Health Services Research Institute, University of Wollongong, Wollongong, New South Wales, Australia.

Background: Evidence about the impact of obesity on surgical resource consumption in the Australian setting is equivocal. Our objectives were to quantify the prevalence of obesity in four frequently performed surgical procedures and explore the association between body mass index (BMI) and hospital resource utilization including procedural duration, length of stay (LOS) and costs.

Methods: A retrospective cohort study of patients undergoing four surgical procedures at a tertiary referral centre in New South Wales, between 1 January 2016 and 31 December 2016, was conducted. Read More

Menopause 2019 Apr 8. Epub 2019 Apr 8.

Department of Gynecology and Obstetrics, School of Medical Sciences, University of Campinas (Unicamp), Campinas (SP), Brazil.

Objective: We analyzed tamoxifen use as a malignancy risk factor in women with endometrial polyps.

Methods: This retrospective study included 675 women who underwent hysteroscopic polypectomy in 2010 to 2015 at the University of Campinas. Women were divided into tamoxifen use (n = 169) and no tamoxifen use (n = 506) groups. Read More

World J Clin Cases 2019 Mar;7(6):753-758

Departamento de Toxicología, Centro de Investigación de Estudios, México City 07360, México.

Background: An isthmocele is a scar defect in the uterine wall due to a cesarean section. Its prevalence is unknown, but it has been associated with secondary infertility. Here, we present a case where the patient suffered from an isthmocele that was associated with persistent hydrometra, which developed during fertilization. Read More

J Obstet Gynaecol India 2019 Apr 31;69(2):166-172. Epub 2018 May 31.

Swapna Health Care, 6-3-1111/19, Nishathbagh, Begumpet, Hyderabad, Telangana 500 016 India.

Objective: This study was conducted at Swapna Health Care (a tertiary centre for endoscopy), to analyse the outcome of hysteroscopic resection of submucous fibroids in 125 symptomatic women.

Materials And Methods: A total of 125 women were diagnosed with submucous fibroids between 1994 and 2017, 83 presented with AUB, 31 with infertility and four with RPL. Seven postmenopausal women had thickened endometrium on routine transvaginal ultrasonography, and hysteroscopy showed submucous fibroids. Read More

Cell Mol Biol (Noisy-le-grand) 2019 Mar 31;65(3):94-100. Epub 2019 Mar 31.

Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital School of Medicine Zhejiang University, Qingchun Road 3rd, Zhejiang Hangzhou 310016, China.

The purpose of this study was to investigate the difference of Twist gene promoter methylation among ovarian ectopic endometrium, eutopic endometrium and non-endometriosis (EMs) endometrium . 15 patients with reproductive age hospitalized at Department of obstetrics and gynecology affiliated to Medicine School of Zhejiang University from January 2013 to June 2016 were selected. Among them, 5 patients underwent laparoscopic surgery due to ovarian type EMs, and were selected after histologic confirmation. Read More

Int J Womens Health 2019 20;11:191-198. Epub 2019 Mar 20.

Department of Gynecology, The Juliane Marie Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark,

Intrauterine adhesions with symptoms like hypomenorrhea or infertility are known under the term Asherman's syndrome. Although the syndrome has been widely investigated, evidence of both prevention of the syndrome and the ideal treatment are missing. Understanding the pathogenesis of intrauterine adherences is necessary for the prevention of the formation of intrauterine scarring. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Mar 26;236:160-165. Epub 2019 Mar 26.

Department of Obstetrics & Gynecology, Shaare Zedek Medical Center, affiliated with the Hebrew University Hadassah School of Medicine Jerusalem, Israel. Electronic address:

Objectives: To identify risk factors and complications associated with 3 stage of labor removal of placental fragments (3 SRPF) by manual uterine revision under a strict protocol.

Study Design: Ten years retrospective register-based cohort study of vaginal deliveries. Women with 3 SRPF n = 3297 (exposed) and those without n = 97,888 (non exposed) were compared. Read More

J Minim Invasive Gynecol 2019 Mar 26. Epub 2019 Mar 26.

The Advanced Gynecologic Surgery Institute, Chicago, IL.

Study Objective: Primary objective is to determine whether incorporation of operative hysteroscopy with biopsy of products of conception, in conjunction with a suction curettage for a first trimester missed abortion, affected the rate of maternal cell contamination when chromosomal analysis was performed on the products of conception. Secondary objective was to determine the rates of retained products of conception with incorporation of hysteroscopy post suction curettage.

Design: Retrospective chart study SETTING: Private, minimally invasive surgery and infertility practice with academic-community hospital affiliation. Read More

Minim Invasive Ther Allied Technol 2019 Mar 25:1-7. Epub 2019 Mar 25.

a Ningbo No. 2 Hospital , Ningbo , People's Republic of China.

Objective: To compare the effectiveness of misoprostol administration orally or vaginally for cervical ripening in women before operative hysteroscopy surgery.

Material And Methods: Two hundred seventy-five women eligible for operative hysteroscopy were recruited for a controlled, blinded, randomized trial. Twenty-two women were excluded from the study. Read More

J Minim Invasive Gynecol 2019 Mar 20. Epub 2019 Mar 20.

From "Arbor Vitae" Centre, Clinica Nuova Villa Claudia, Rome, Italy (Drs Mazzon, Di Angelo Antonio, and Villani), Department of Surgical and Biomedical Sciences, Section of Obstetrics and Gynecology, S. Maria della Misericordia Hospital, University of Perugia, Perugia, Italy (Drs Gerli and Favilli), Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea Hospital, Faculty of Medicine and Psychology University of Rome "Sapienza" Italy (Dr Assorgi).. Electronic address:

Study Objectives: To evaluate the outcomes of a new hysteroscopic technique for the treatment of longitudinal vaginal septum.

Design: A retrospective study.

Setting: Arbor Vitae Center for Endoscopic Gynecology, Rome, Italy. Read More

BJOG 2019 Mar 20. Epub 2019 Mar 20.

Reproductive Endocrinology and Infertility, Carolinas Medical Center, Charlotte, NC, USA.

Int J Hyperthermia 2019 20;36(1):421-427. Epub 2019 Mar 20.

b Department of Pathology , West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University , Chengdu , China.

Objective: To evaluate the safety and feasibility of combined procedures: HIFU combined with systemic MTX followed by ultrasound-guided curettage or hysteroscopic resection while treating placenta accreta (PA).

Method: This study included 21 patients diagnosed with retained PA with marked vascularity after abortion or delivery from July 2015 to December 2017. Patients with high serum β-hCG level (≥100 mIU/mL) received systemic MTX + HIFU treatment for 3 days and the ones with low β-hCG level (<100 mIU/mL) only received USgHIFU treatment for 3 days before ultrasound-guided curettage or hysteroscopic resection. Read More

Medicine (Baltimore) 2019 Mar;98(11):e14721

Department of Surgical, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.

This study aims to discuss the operative skills of hysteroscopic tubal embolization and reduce the occurrence of complications.Ninety-four patients were divided into group A and group B. The main surgical technique in group A: when the inner sleeve is sent to the fallopian tube and no longer accessible (but no >3 cm), remove the guide wire and put into the microcoil. Read More

J Minim Invasive Gynecol 2019 Mar 14. Epub 2019 Mar 14.

Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Hunan, China (all authors). Electronic address:

Study Objective: To identify factors that affect reproductive outcomes after hysteroscopic adhesiolysis in patients with severe intrauterine adhesions (IUAs, scored between 9 and 12 according to the American Fertility Society classification) and amenorrhea.

Design: A retrospective cohort study.

Setting: A university-affiliated hospital. Read More

J Minim Invasive Gynecol 2019 Mar 15. Epub 2019 Mar 15.

Department of Gynecological Endocrinology and Reproductive Medicine, Medical University of Vienna, Vienna, Austria (Drs. Ott, Hager, Nouri, Marschalek, and Kurz). Electronic address:

Study Objective: To evaluate whether the presence of a visualizable "flow" effect in the fallopian tube ostia in hysteroscopy was predictive of tubal patency.

Design: A prospective cohort study.

Setting: In a prospective study, infertile women who underwent surgery because of infertility between March and November 2018 were included. Read More

J Minim Invasive Gynecol 2019 Mar 8. Epub 2019 Mar 8.

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Hashomer, Israel (all authors).

Study Objective: Cesarean scar defect (CSD) is often associated with postmenstrual bleeding, infertility, and pain. Hysteroscopic CSD repair was described in the past, mainly as excision of the proximal edge of the defect to allow continuous blood flow during menstruation. In this study we aimed to evaluate the efficacy of extensive hysteroscopic cesarean scar niche excision in symptomatic patients. Read More

Fertil Steril 2019 Apr 8;111(4):828-830. Epub 2019 Mar 8.

Gynecology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Objectives: To describe our technique for transvaginal treatment of isthmocele.

Design: Surgical video article. Local Institutional Review Board approval for the video reproduction was obtained. Read More

J Minim Invasive Gynecol 2019 Mar 6. Epub 2019 Mar 6.

Research Center for Thalassemia and Hemoglobinopathy, Ahvaz, Iran (Dr. Choghakabodi).

Study Objective: The identification of less invasive methods with acceptable diagnostic value for evaluating intrauterine abnormalities can improve the satisfaction of patients and physicians. Although hysteroscopy plus biopsy has favorable predictive and diagnostic values, limited studies have evaluated its value, and the exact value of this method is not completely understood. The aim of this study was to evaluate the prevalence of chronic endometritis in patients with recurrent implantation failure (RIF) and recurrent pregnancy loss (RPL) by hysteroscopy and immunohistochemistry. Read More

Photodiagnosis Photodyn Ther 2019 Mar 5. Epub 2019 Mar 5.

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, 160-8582, Japan.

Endometrial cancer is diagnosed by endometrial biopsy, imaging and hysteroscopy, but it is sometimes difficult to find small lesions. 5-aminolevulinic acid (5ALA) forms protoporphyrin IX, which accumulates in tumors and fluoresces upon light irradiation. 5ALA is used for photodynamic diagnosis (PDD) for detecting malignant diseases. Read More

JSLS 2019 Jan-Mar;23(1)

Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Background And Objectives: An increasing number of women are seeking removal of the Essure sterilization device due to symptoms including pelvic pain, abnormal bleeding, and allergic reaction. A fraction of these women also desire a future pregnancy and request sterilization reversal at the time of device removal. We present a novel technique for Essure reversal in addition to our experience with three cases. Read More

JSLS 2019 Jan-Mar;23(1)

Department of Obstetrics and Gynecology, Ufuk University School of Medicine, Ankara, Turkey.

Background And Objectives: To compare the efficacy of 3 different techniques for prevention of adhesion reformation after hysteroscopic adhesiolysis in patients with moderate-to-severe intrauterine adhesions. Short-term assisted reproductive outcomes were also compared.

Study Design: Total of 72 cases were randomized to Lippes loop intrauterine device (IUD) only, IUD plus a new crosslinked hyaluronan (NCH) gel, or NCH gel only following hysteroscopic adhesiolysis. Read More

J Obstet Gynaecol Res 2019 Mar 5. Epub 2019 Mar 5.

Department of Obstetrics and Gynecology, University of Debrecen Clinical Center, Debrecen, Hungary.

Fertil Steril 2019 Mar;111(3):607-608

Minimally Invasive Surgery, Baylor College of Medicine, Houston, Texas. Electronic address:

Objective: To evaluate the feasibility of laparoscopic single-incision repair for a cesarean scar defect (CSD).

Design: Step-by-step explanation of surgery using an instructive video, with Institutional Review Board approval.

Setting: University Hospital, Shandong Province, People's Republic of China. Read More

Gynecol Endocrinol 2019 Feb 26:1-5. Epub 2019 Feb 26.

a Department of Surgical and Medical Sciences and Translational Medicine , Sapienza University of Rome, Sant'Andrea University Hospital , Rome , Italy.

Inadequate uterine receptivity is responsible for two-third of implanting failures. Aim of the study was to investigate the role of epithelial adherence and tight-junction molecules expressed by human endometrium in predicting womens' fertility outcome. A total of 76 consecutive women, including 24 fertile (G1), 40 primary infertile (G2), and 12 recurrent pregnancy loss (RPL, G3) women, who underwent diagnostic hysteroscopy plus endometrial biopsy between 2005 and 2016 at the Gynecology Division of Sant'Andrea Hospital, Sapienza University of Rome, in Italy, were retrospectively identified and included into the study. Read More

In Vivo 2019 Mar-Apr;33(2):515-521

Reproductive Medicine Unit, Genesis Athens Clinic, Athens, Greece.

Background/aim: Patients diagnosed with chronic endometritis (CE) may fail to respond to standard antibiotic treatment. The driver behind the approach reported here was the imperative need for alternative therapeutic solutions.

Case Report: This case report presents a woman with CE and premature ovarian insufficiency having experienced repeated implantation failures following donated embryo transfers. Read More

BJOG 2019 Feb 22. Epub 2019 Feb 22.

Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.

Objective: To evaluate whether vaginoscopy or standard hysteroscopy was more successful in the outpatient setting.

Design: Randomised controlled multicentre trial.

Setting: Outpatient hysteroscopy clinics at two UK hospitals. Read More

Biomed Res Int 2019 21;2019:8910374. Epub 2019 Jan 21.

Radiodiagnosis Departments, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.

Background: Abnormal uterine bleeding (AUB) may be acute or chronic and is defined as bleeding from the uterine corpus that is abnormal in regularity, volume, frequency, or duration and occurs in the absence of pregnancy. It is a widespread complaint in the primary care units. The prevalence of abnormal bleeding is up to 30% among women of reproductive age. Read More

Minim Invasive Ther Allied Technol 2019 Feb 22:1-10. Epub 2019 Feb 22.

f Department of Medicine , Universidad Cardenal Herrera-CEU CEU Universities , Valencia , Spain.

Outpatient hysteroscopy has become the standard technique for gynaecological exploration of the uterine cavity. The most common reason for failure of the procedure is pain. During the last decade many studies were carried out to improve the equipment as well as the procedural technical aspects. Read More

Rev Med Liege 2019 Feb;74(2):61-62

Service de Gynécologie, CHC Saint-Vincent, Liège, Belgique.

Med J Islam Repub Iran 2018 22;32:90. Epub 2018 Sep 22.

School of Medicine, International Campus (IC), Iran Medical University of Medical Sciences, Tehran, Iran.

Electrosurgery is widely used in reproductive related surgeries and technological advancements to improve efficacy and reduce potential complications. However, some reports have indicated lack of sufficient knowledge and training about basic principles and technical aspects of electrosurgery among obstetricians and gynecologists. In this paper we present a summary on basic concepts and principles of electrosurgery and review the recent evidence on the use of electrosurgical devices in gynecologic procedures including endometrial ablation, gynecologic malignancies, loop electrode excision procedure (LEEP), and infertility. Read More

Gynecol Minim Invasive Ther 2019 Jan-Mar;8(1):33-35. Epub 2019 Jan 23.

Department of Obstetrics and Gynecology, Queen Elizabeth Hospital, Kowloon, Hong Kong.

Conventionally, surgical management of retained placental tissue is largely performed using blind dilatation and curettage. Hysteroscopic removal using diathermy loop has been shown to be successful while increasing complete removal rates and reducing risk of uterine perforation. Our two cases demonstrated that complete removal of placental tissues can be achieved with hysteroscopic morcellation device which is known to be associated with less operative time and less operative risk compared to diathermy loop. Read More

Int J Gynaecol Obstet 2019 May 13;145(2):212-218. Epub 2019 Mar 13.

Reproductive Medicine Center, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, China.

Objective: To assess three-dimensional (3D) ultrasound combined with power Doppler (PD) for the differential diagnosis of endometrial lesions among infertile women.

Methods: A prospective study carried out at a reproductive medicine center in Luoyang, China, between January and December 2015. The inclusion criteria were asymptomatic infertility with normal endometrium or specific endometrial lesions. Read More

Medicine (Baltimore) 2019 Feb;98(7):e14075

Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

Objective: To study if hysteroscopy (HSC) before starting an in-vitro fertilization (IVF) cycle improves IVF outcomes in women with recurrent implantation failure (RIF).

Methods: The Medline, Cochrane, EMBASE, and Google Scholar databases were searched using the following keywords until March 31, 2017: in-vitro fertilization; infertility; hysteroscopy; recurrence; embryo implantation; and pregnancy. Randomized controlled trials (RCTs), two-arm prospective studies, and retrospective studies were included. Read More

Minerva Ginecol 2019 Feb 12. Epub 2019 Feb 12.

Baby Center, Center for Reproductive Medicine, São Paulo, Brazil -

Background: 3D printing has wide application in medicine while it provides customizability and precision for anatomical model development. Our aims were to perform a systematic review and to explore the use of 3D printing applications on human reproduction and reproductive surgery.

Methods: We have performed a systematic review in PubMed database to assess previous publications within 3D printing in human reproduction and gynecology. Read More

Medicine (Baltimore) 2019 Feb;98(6):e14464

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital.

The risk of malignancies and related factors among asymptomatic postmenopausal women with thickened endometrium in transvaginal sonography (TVS) are unclear.In this longitudinal study at a tertiary teaching hospital, all medical records of hysteroscopy were searched and retrospectively reviewed according to age, TVS results and diseases coded as International Classification of Diseases version 10. Asymptomatic postmenopausal women with endometrial thickness ≥5 mm from January 2006 to January 2016 were included. Read More

Acta Obstet Gynecol Scand 2019 Feb 3. Epub 2019 Feb 3.

Gynecology and Obstetrics Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.

Introduction: Atypical polypoid adenomyoma is an uncommon uterine lesion which can coexist with endometrial atypical hyperplasia and/or cancer. Atypical polypoid adenomyoma affects premenopausal women in most cases, but it shows high recurrence rate if conservatively treated. To date, the management of patients is based on low-quality evidence and is not standardized. Read More

Fertil Steril 2019 Mar 30;111(3):547-552. Epub 2019 Jan 30.

Department of Obstetrics and Gynaecology, Faculty of Medicine, Assiut University, Assiut, Egypt. Electronic address:

Objective: To evaluate the evidence about the safety and efficacy of tramadol in pain relief during diagnostic outpatient hysteroscopy (OH).

Design: Systematic review and meta-analysis of randomized controlled trials.

Setting: Not applicable. Read More

J Minim Invasive Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy (Dr. Resta).

Study Objective: To investigate the correlation between endometrial polyps (EPs) and chronic endometritis (CE).

Design: Single-center retrospective case-control study.

Setting: Academic center. Read More

Ultrasound Obstet Gynecol 2019 Jan 28. Epub 2019 Jan 28.

Department of Obstetrics and Gynecology; Maastricht UMC+, Maastricht, GROW- School for Oncology and Developmental Biology.

Introduction: Postmenopausal bleeding is a common complaint and is related to several benign and malignant conditions. Frequent findings in women with postmenopausal bleeding are endometrial polyps. The risk of a focal (pre)malignancy in a polyp in women with postmenopausal bleeding is up to 6%. Read More

J Minim Invasive Gynecol 2019 Jan 26. Epub 2019 Jan 26.

Department of Medical, Surgical, and Health Sciences, University of Trieste, Trieste, Italy (Dr. Ricci).

Study Objective: To evaluate the efficacy of total surgical treatment of ectopic cervical pregnancy [1] with a minimally invasive approach performed by hysteroscopy [2].

Design: Step-by-step video demonstration of the surgical technique using 5 mm hysteroscopy followed by 10 mm resectoscopy.

Setting: A research and university hospital (IRCCS Burlo Garofolo, Trieste, Italy). Read More

Fertil Steril 2019 Apr 22;111(4):772-779. Epub 2019 Jan 22.

Hysteroscopic Centre, Fu Xing Hospital, Capital Medical University, Beijing, People's Republic of China.

Objective: To evaluate the role of hysteroscopy in the diagnosis of chronic endometritis (CE).

Design: Retrospective cohort study.

Setting: University teaching hospital. Read More

Semin Perinatol 2019 Mar 20;43(2):74-79. Epub 2018 Dec 20.

Department of Obstetrics & Gynecology, Columbia University Medical Center, Fertility Center, 5 Columbus Circle, PH, New York, New York, USA.

Objective: To review the current understanding of the role the uterus plays in recurrent pregnancy loss.

Findings: Congenital and acquired uterine abnormalities are associated with recurrent pregnancy loss in the first and second trimester. Relevant congenital Mullerian tract anomalies include unicornuate, didelphys, bicornuate and septate uteri. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Mar 17;234:108-111. Epub 2019 Jan 17.

Department of Obstetrics and Gynecology, Assaf Harofe Medical Center, Affiliated with Sackler School of Medicine, Tel Aviv University, Israel.

Objective: To compare the prevalence of postpartum retained products of conception (RPOC) among parturients with a history of third stage of labor placental complications and parturients without those complications.

Study Design: All women operated for postpartum RPOC following vaginal delivery by hysteroscopy or suction curettage between January 2013 and December 2017 were included in the study. Their medical records were reviewed for the occurrence of third stage of labor placental complications (including early postpartum hemorrhage treated with uterotonics, manual separation of the placenta, and revision of the uterine cavity for removal of cotyledons). Read More

Gynecol Oncol 2019 Apr 21;153(1):55-62. Epub 2019 Jan 21.

Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai 200011, China. Electronic address:

Objective: This study aimed to evaluate the efficacy of comprehensive hysteroscopic evaluation and lesion resection combined with progestin therapy in young patients with endometrial atypical hyperplasia (EAH) and early stage endometrial cancer (EEC) who wished to preserve their fertility.

Methods: Patients with EAH (n = 120) or well-differentiated EEC (n = 40, FIGO stage IA, without myometrial invasion) were retrospectively included. All patients received constant oral progestin combined with hysteroscopic evaluation every 3 months until achieving complete response (CR). Read More

N Engl J Med 2019 01;380(4):325-334

From the Department of Obstetrics and Gynaecology, University of Auckland (S.L., D.O., C.F.), and Women's Health (L. Sadler) and Fertility Plus (D.G., C.F.), Auckland District Health Board, Auckland, Fertility Associates, Christchurch (S.A.W.), and Fertility Associates, Wellington (L. Searle, S.M.) - all in New Zealand; Bath Fertility Centre, Bath (S.A., E.N.), the Department of Medical Statistics, Manchester University NHS Foundation Trust, Manchester (J.W.), and the Department of Obstetrics and Gynaecology, King's College Hospital (K.V., H.H.), University College Hospital (L.W.), Homerton Fertility Centre, Homerton University Hospital NHS Foundation Trust (P.B.), and Guy's Hospital (Y.K.), London - all in the United Kingdom; the Department of Obstetrics and Gynecology, Institute of Clinical Sciences, University of Gothenburg, Reproductive Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden (C.S., A.S., C.B.); Leuven University Fertility Center, Department of Obstetrics and Gynecology, University Hospitals, Leuven, Belgium (A.H., K.P.); and Reproductive Services, Royal Women's Hospital, Melbourne, VIC, Australia (W.T.T.).

Background: Endometrial scratching (with the use of a pipelle biopsy) is a technique proposed to facilitate embryo implantation and increase the probability of pregnancy in women undergoing in vitro fertilization (IVF).

Methods: We conducted a pragmatic, multicenter, open-label, randomized, controlled trial. Eligible women were undergoing IVF (fresh-embryo or frozen-embryo transfer), with no recent exposure to disruptive intrauterine instrumentation (e. Read More