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Int J Gynaecol Obstet 2019 Feb 14. Epub 2019 Feb 14.

Reproductive Medicine Center, Luoyang Center Hospital of Zhengzhou University, Luoyang, China.

Objective: To assess three-dimensional (3D) ultrasound combined with power Doppler (PD) for the differential diagnosis of endometrial lesions among infertile women.

Methods: A prospective study carried out at a reproductive medicine center in Luoyang, China, between January and December 2015. The inclusion criteria were asymptomatic infertility with normal endometrium or specific endometrial lesions. Read More

Medicine (Baltimore) 2019 Feb;98(7):e14075

Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

Objective: To study if hysteroscopy (HSC) before starting an in-vitro fertilization (IVF) cycle improves IVF outcomes in women with recurrent implantation failure (RIF).

Methods: The Medline, Cochrane, EMBASE, and Google Scholar databases were searched using the following keywords until March 31, 2017: in-vitro fertilization; infertility; hysteroscopy; recurrence; embryo implantation; and pregnancy. Randomized controlled trials (RCTs), two-arm prospective studies, and retrospective studies were included. Read More

Minerva Ginecol 2019 Feb 12. Epub 2019 Feb 12.

Baby Center, Center for Reproductive Medicine, São Paulo, Brazil -

Background: 3D printing has wide application in medicine while it provides customizability and precision for anatomical model development. Our aims were to perform a systematic review and to explore the use of 3D printing applications on human reproduction and reproductive surgery.

Methods: We have performed a systematic review in PubMed database to assess previous publications within 3D printing in human reproduction and gynecology. Read More

Medicine (Baltimore) 2019 Feb;98(6):e14464

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital.

The risk of malignancies and related factors among asymptomatic postmenopausal women with thickened endometrium in transvaginal sonography (TVS) are unclear.In this longitudinal study at a tertiary teaching hospital, all medical records of hysteroscopy were searched and retrospectively reviewed according to age, TVS results and diseases coded as International Classification of Diseases version 10. Asymptomatic postmenopausal women with endometrial thickness ≥5 mm from January 2006 to January 2016 were included. Read More

Acta Obstet Gynecol Scand 2019 Feb 3. Epub 2019 Feb 3.

Gynecology and Obstetrics Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.

Introduction: Atypical polypoid adenomyoma (APA) is an uncommon uterine lesion, which can coexist with endometrial atypical hyperplasia and/or cancer. APA affects premenopausal women in most cases, but it shows high recurrence rate if conservatively treated. To date, the management of patients is based on low quality evidence and not standardized. Read More

Fertil Steril 2019 Jan 30. Epub 2019 Jan 30.

Department of Obstetrics and Gynaecology, Faculty of Medicine, Assiut University, Assiut, Egypt. Electronic address:

Objective: To evaluate the evidence about the safety and efficacy of tramadol in pain relief during diagnostic outpatient hysteroscopy (OH).

Design: Systematic review and meta-analysis of randomized controlled trials.

Setting: Not applicable. Read More

J Minim Invasive Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Department of Emergency and Transplant of Organs (DETO), University of Bari, Italy, Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy.

Study Objective: To investigate the correlation between endometrial polyps (EPs) and chronic endometritis (CE).

Design: Single-center retrospective case-control study.

Setting: Academic Centre. Read More

Ultrasound Obstet Gynecol 2019 Jan 28. Epub 2019 Jan 28.

Department of Obstetrics and Gynecology; Maastricht UMC+, Maastricht, GROW- School for Oncology and Developmental Biology.

Introduction: Postmenopausal bleeding is a common complaint and is related to several benign and malignant conditions. Frequent findings in women with postmenopausal bleeding are endometrial polyps. The risk of a focal (pre)malignancy in a polyp in women with postmenopausal bleeding is up to 6%. Read More

J Minim Invasive Gynecol 2019 Jan 25. Epub 2019 Jan 25.

Department of Medical, Surgical, and Health Sciences, University of Trieste, 34149 Trieste, Italy.

Study Objective: To evaluate the efficacy of a total surgical treatment of ectopic cervical pregnancy, with a minimally invasive approach performed by hysteroscopy.

Design: Step-by-step video demonstration of the surgical technique using 5 mm hysteroscopy followed by 10 mm resectoscopy.

Setting: A Research and University Hospital; IRCCS Burlo Garofolo of Trieste, Italy. Read More

Fertil Steril 2019 Jan 22. Epub 2019 Jan 22.

Hysteroscopic Centre, Fu Xing Hospital, Capital Medical University, Beijing, People's Republic of China.

Objective: To evaluate the role of hysteroscopy in the diagnosis of chronic endometritis (CE).

Design: Retrospective cohort study.

Setting: University teaching hospital. Read More

Semin Perinatol 2018 Dec 20. Epub 2018 Dec 20.

Department of Obstetrics & Gynecology, Columbia University Medical Center, Fertility Center, 5 Columbus Circle, PH, New York, New York, USA.

Objective: To review the current understanding of the role the uterus plays in recurrent pregnancy loss.

Findings: Congenital and acquired uterine abnormalities are associated with recurrent pregnancy loss in the first and second trimester. Relevant congenital Mullerian tract anomalies include unicornuate, didelphys, bicornuate and septate uteri. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Jan 17;234:108-111. Epub 2019 Jan 17.

Department of Obstetrics and Gynecology, Assaf Harofe Medical Center, Affiliated with Sackler School of Medicine, Tel Aviv University, Israel.

Objective: To compare the prevalence of postpartum retained products of conception (RPOC) among parturients with a history of third stage of labor placental complications and parturients without those complications.

Study Design: All women operated for postpartum RPOC following vaginal delivery by hysteroscopy or suction curettage between January 2013 and December 2017 were included in the study. Their medical records were reviewed for the occurrence of third stage of labor placental complications (including early postpartum hemorrhage treated with uterotonics, manual separation of the placenta, and revision of the uterine cavity for removal of cotyledons). Read More

Gynecol Oncol 2019 Jan 21. Epub 2019 Jan 21.

Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai 200011, China. Electronic address:

Objective: This study aimed to evaluate the efficacy of comprehensive hysteroscopic evaluation and lesion resection combined with progestin therapy in young patients with endometrial atypical hyperplasia (EAH) and early stage endometrial cancer (EEC) who wished to preserve their fertility.

Methods: Patients with EAH (n = 120) or well-differentiated EEC (n = 40, FIGO stage IA, without myometrial invasion) were retrospectively included. All patients received constant oral progestin combined with hysteroscopic evaluation every 3 months until achieving complete response (CR). Read More

N Engl J Med 2019 01;380(4):325-334

From the Department of Obstetrics and Gynaecology, University of Auckland (S.L., D.O., C.F.), and Women's Health (L. Sadler) and Fertility Plus (D.G., C.F.), Auckland District Health Board, Auckland, Fertility Associates, Christchurch (S.A.W.), and Fertility Associates, Wellington (L. Searle, S.M.) - all in New Zealand; Bath Fertility Centre, Bath (S.A., E.N.), the Department of Medical Statistics, Manchester University NHS Foundation Trust, Manchester (J.W.), and the Department of Obstetrics and Gynaecology, King's College Hospital (K.V., H.H.), University College Hospital (L.W.), Homerton Fertility Centre, Homerton University Hospital NHS Foundation Trust (P.B.), and Guy's Hospital (Y.K.), London - all in the United Kingdom; the Department of Obstetrics and Gynecology, Institute of Clinical Sciences, University of Gothenburg, Reproductive Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden (C.S., A.S., C.B.); Leuven University Fertility Center, Department of Obstetrics and Gynecology, University Hospitals, Leuven, Belgium (A.H., K.P.); and Reproductive Services, Royal Women's Hospital, Melbourne, VIC, Australia (W.T.T.).

Background: Endometrial scratching (with the use of a pipelle biopsy) is a technique proposed to facilitate embryo implantation and increase the probability of pregnancy in women undergoing in vitro fertilization (IVF).

Methods: We conducted a pragmatic, multicenter, open-label, randomized, controlled trial. Eligible women were undergoing IVF (fresh-embryo or frozen-embryo transfer), with no recent exposure to disruptive intrauterine instrumentation (e. Read More

Niger J Clin Pract 2019 Jan;22(1):9-15

Department of Obstetrics and Gynaecology, University of Portharcout Teaching Hospital, Port Harcourt, Nigeria.

Background: Intrauterine lesions are important causes of infertility. This study aims to evaluate the abnormal findings at hysteroscopy among infertile women seen in 2 new Fertility/Gynaecological Endoscopy units in Nigeria.

Methods: A prospective study of 159 infertile women who had diagnostic hysteroscopy in Nnamdi Azikiwe University Teaching hospital Nnewi and Holy Rosary Specialist Hospital, Onitsha to evaluate the intrauterine lesions seen. Read More

Fertil Steril 2019 Jan 18. Epub 2019 Jan 18.

University of Glasgow, Glasgow, and Oriel College, University of Oxford, Oxford, United Kingdom.

Ther Clin Risk Manag 2019 7;15:83-89. Epub 2019 Jan 7.

Department of Gynecologic Oncology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, China,

Purpose: The purpose of this study was to investigate the efficiency, complications, and subsequent fertility outcomes of two methods in treating patients with cesarean scar pregnancy (CSP) after receiving uterine artery embolization (UAE) treatment.

Patients And Methods: A total of 62 CSP patients who visited our hospital and underwent UAE from January 2013 to January 2018 were retrospectively analyzed. Patients were either treated by dilation and curettage (D&C) guided by ultrasonography or hysteroscopy. Read More

Arch Gynecol Obstet 2019 Jan 19. Epub 2019 Jan 19.

1st Department of Obstetrics and Gynecology, Papageorgiou General Hospital, Ring Road, Municipality Pavlos Melas, N. Efkarpia, 56403, Thessaloniki, Greece.

Study Objective: To estimate the diagnostic accuracy of three-dimensional ultrasonography (3D US) compared to hysteroscopy/laparoscopy, in the investigation of uterine congenital anomalies using the ESHRE/ESGE classification of female genital tract congenital anomalies.

Design: Prospective blind, comparative, cohort study.

Setting: University Tertiary Hospital and affiliated private Hospital. Read More

J Minim Invasive Gynecol 2019 Jan 16. Epub 2019 Jan 16.

Department of Obstetrics and Gynecology, Hospital das Forças Armadas, Lisbon, Portugal (Drs. Mairos and Di Martino).

Study Objective: To assess how the location of intracavitary lesions during office hysteroscopy influences pain scores.

Design: Cohort study.

Setting: Department of Obstetrics and Gynecology, Hospital das Forças Armadas, Lisbon, Portugal. Read More

Biomed Res Int 2018 13;2018:8704346. Epub 2018 Dec 13.

Head of the Hysteroscopy Unit, Del Mar University Hospital, Barcelona, Spain.

Introduction: Insulin-like growth factor 1 is a peptide growth factor that promotes cell proliferation and inhibits apoptosis. The bioavailability of is regulated by the insulin-like growth factor binding protein 3 Genetic variations influence the levels of and . The purpose of this study was to examine the association of polymorphisms and with risk of endometrial polyps. Read More

J Obstet Gynaecol Can 2019 Jan 10. Epub 2019 Jan 10.

Department of Obstetrics and Gynecology, Kaplan Medical Center, Faculty of Health Sciences, Hebrew University, Rehovot, Israel.

Objective: This study sought to compare the value of transvaginal ultrasonography (TVUS) and hysteroscopy in premenopausal and postmenopausal women in the diagnosis of endometrial polyp.

Methods: The records of 694 women with an ultrasonographic diagnosis of suspected endometrial polyp who underwent hysteroscopy were studied. Patients were divided into two groups according to menopausal status, and a comparison was made between two groups. Read More

Taiwan J Obstet Gynecol 2019 Jan;58(1):90-93

Department of Obstetrics and Gynecology, Show Chwan Memorial Hospital, Changhua, Taiwan. Electronic address:

Objective: The standard treatment for endometrial cancer is surgery with hysterectomy. However, this procedure will cause infertility in young women who desire to preserve pregnant ability. Conservative management with hormone therapy has been shown to be satisfactory in both tumor control and fertility preservation. Read More

J Clin Pharm Ther 2019 Jan 11. Epub 2019 Jan 11.

Department of Anesthesiology and Reanimation, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.

What Is Known And Objective: The most appropriate sedative agent for conscious sedation in minor hysteroscopic surgeries is still unclear. Dexmedetomidine a sedative and analgesic agent, may be appropriate for outpatient procedures. The aim of our study was to compare the sedative, analgesic and hemodynamic effects of dexmedetomidine vs propofol in combination with fentanyl and midazolam in patients undergoing minor hysteroscopy surgery. Read More

Hum Reprod Update 2019 Jan 9. Epub 2019 Jan 9.

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.

Background: Early reproductive failure is the most common complication of pregnancy with only 30% of conceptions reaching live birth. Establishing a successful pregnancy depends upon implantation, a complex process involving interactions between the endometrium and the blastocyst. It is estimated that embryos account for one-third of implantation failures, while suboptimal endometrial receptivity and altered embryo-endometrial dialogue are responsible for the remaining two-thirds. Read More

Gynecol Endocrinol 2019 Jan 6:1-5. Epub 2019 Jan 6.

a Department of Obstetrics and Gynecology , Hacettepe University School of Medicine , Ankara , Turkey.

In this retrospective cohort study, a total of 707 couples underwent in vitro fertilization (IVF) at Hacettepe University Hospital between 01 January 2010 and 01 November 2014 with their chronologically first cycle were evaluated. Patients who have diagnostic hysteroscopy prior to first IVF cycle served as a study group (n = 42) and patients without diagnostic hysteroscopy served as control group (n = 282). In study group in all patients, diagnostic hysteroscopy was performed at the follicular phase of previous menstrual cycle, namely immediately before ovarian stimulation (OS) cycle. Read More

J Minim Invasive Gynecol 2019 Jan 4. Epub 2019 Jan 4.

Department of Obstetrics and Gynecology, The Yitzhak Shamir Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (all authors).. Electronic address:

Study Objective: To investigate whether hysteroscopic features can contribute to the diagnosis of malignancy in endometrial polyps.

Design: Retrospective review.

Setting: Obstetrics and gynecology department. Read More

J Formos Med Assoc 2019 Jan 2. Epub 2019 Jan 2.

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital (Linkou), Tao-Yuan, Taiwan; Chang Gung University College of Medicine, Tao-Yuan, Taiwan.

With the advances in miniature instruments, office hysteroscopy on conscious patients has been the standard to explore the intrauterine pathology, with the ability to perform some minor procedures concomitantly. Patients usually appreciate the efficient "see and treat" procedures with such minimal discomfort that exempt from the inconvenience of going into the operating room and the need for anesthesia. However, controversies exist in the appropriateness of its application in some clinical situations. Read More

Arch Gynecol Obstet 2019 Jan 4. Epub 2019 Jan 4.

Department of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.

J Minim Invasive Gynecol 2018 Dec 24. Epub 2018 Dec 24.

Mercy Hospital for Women, 163 Studley road, Heidelberg, Melbourne, Victoria 3984, Australia. Electronic address:

Study Objective: To study the hypothesis that the LNG-IUD can have a role in the treatment of endometrial polyps confirmed at outpatient hysteroscopy in premenopausal women.

Design: Canadian task force classification - Level II1 (controlled trial which is not randomised) SETTING: Outpatient hysteroscopy PATIENTS: premenopausal women who had a polyp diagnosed at outpatient hysteroscopy INTERVENTIONS: Premenopausal women who had a polyp diagnosed at outpatient hysteroscopy and had a LNG-IUD inserted were booked for GA hysteroscopy and polypectomy through the standard booking process. A contemporaneous control was taken sequentially from the outpatient hysteroscopy database to match the case. Read More

Case Rep Obstet Gynecol 2018 21;2018:1536801. Epub 2018 Nov 21.

Centre for Assisted Reproduction and Endocrinology, Singapore General Hospital, Outram Road, Singapore.

The management of retained products of conception (RPOC) may be medical or surgical. Surgical options include blind curettage, ultrasound guided curettage, or curettage under direct vision via hysteroscopy. The definitive management of patients presenting with retained products of conception will depend on several factors: severity of bleeding, presence of hemodynamic instability or infection, and patient preference. Read More

J Obstet Gynaecol Res 2018 Dec 21. Epub 2018 Dec 21.

Department of Obstetrics and Gynecology, Mansoura Faculty of Medicine, Mansoura University Hospital, Gomhoria Street, Mansoura 11271, Egypt.

Pan Afr Med J 2018 16;30:208. Epub 2018 Jul 16.

Service de Radiothérapie, CHU Hassan II Fès, Maroc.

In this paper, we report a case of primary squamous cell carcinoma of the endometrium (PSCCE) with a literature review. A 64-year-old woman was admitted because of postmenopausal bleeding. The gynecological exam found bleeding from the endocervix. Read More

J Minim Invasive Gynecol 2018 Dec 17. Epub 2018 Dec 17.

Department of Gynecology and Obstetrics, Women's Hospital, Zhejiang University School of Medicine, Zhejiang Province, China (Drs. Qi and Lv); Center for Uterine Cancer Diagnosis and Therapy Research of Zhejiang Province, Zhejiang Province, China (Dr. Lv).. Electronic address:

Study Objective: To evaluate the efficacy of hysteroscopy-assisted laparoscopy as a treatment strategy for type 2 cesarean scar pregnancy at gestational age >8 weeks.

Design: Retrospective case series (Canadian Task Force classification II-3).

Setting: A tertiary hospital. Read More

J Hum Reprod Sci 2018 Jul-Sep;11(3):286-290

Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: Midtrimester surgical abortions often result in retained intrauterine fetal bones and consequent secondary infertility.

Aim: To study the incidence of women presenting with retained intrauterine bones as a cause of secondary infertility in a tertiary level Indian hospital and pregnancy rates following retrieval of these fragments.

Setting And Design: Retrospective data analysis in the infertility clinic of PGIMER (Post Graduate Institute of Medical Education and Research), a tertiary level hospital of Northern India. Read More

Gynecol Obstet Invest 2018 Dec 14:1-13. Epub 2018 Dec 14.

Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Background/aims: Ulipristal acetate ([UPA], Esmya®) is an orally active selective progesterone-receptor modulator that has been approved as preoperative treatment for uterine myomas. This systematic review aims to summarize the available data on surgical outcomes of patients undergoing myomectomy by hysteroscopy or by laparoscopy after preoperative treatment with UPA.

Methods: this review was performed following PRISMA guidelines and was registered in PROSPERO (CRD42018092201). Read More

J Gynecol Obstet Hum Reprod 2018 Dec 12. Epub 2018 Dec 12.

AP-HP, Department of Gynecology and Obstetrics, Hospital Bicêtre, GHU Sud, F-94276, Le Kremlin Bicêtre, France; INSERM, U1018, Centre of research in Epidemiology and population health (CESP), F-94276, Le Kremlin Bicêtre, France; Faculty of medicine, University Paris Saclay, F-94276, Le Kremlin Bicêtre, France.

Retained product of conception complicates nearly 1% of pregnancies and can lead to synechiae and compromise ulterior fertility. The aim of this study is to evaluate efficiency of operative hysteroscopy in management of retained products of conception (RPOC). Secondary objectives are assessments of intra-uterine adhesions rate and later fertility. Read More

Isr Med Assoc J 2018 Dec;20(12):761-764

Department of Obstetrics and Gynecology, Wolfson Medical Center, Holon, Israel, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Different clinical and sonographic parameters have been suggested to identify patients with retained products of conception. In suspected cases, the main treatment is hysteroscopic removal.

Objectives: To compare clinical, sonographic, and intraoperative findings in cases of hysteroscopy for retained products of conception, according to histology. Read More

JSLS 2018 Oct-Dec;22(4)

School of Medicine, Istanbul University, Department of Obstetrics and Gynecology, Istanbul, Turkey.

Background And Objectives: The authors sought to assess the effect of the use of a new crosslinked hyaluronan (NCH) gel on the prevention of intrauterine adhesions (IUAs) in women underwent curettage in the second trimester.

Methods: Between June 2016 and September 2017, 60 patients who underwent curettage for retained placental tissue after medically induced or spontaneous pregnancy loss in the second trimester were enrolled in the study. The patients were randomly assigned to 1 of 2 groups: Group 1 patients received curettage plus NCH gel (intervention group), and group 2 patients received curettage alone (control group). Read More

Biomed Res Int 2018 8;2018:9494101. Epub 2018 Nov 8.

Department of Minimally Invasive Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China.

Objective: To compare the effect of intrauterine suitable balloon (ISB) and Foley balloon (FB) in the prevention of adhesion after hysteroscopic adhesiolysis in patients with intrauterine adhesions (IUAs).

Methods: A retrospective study was conducted on 150 women with moderate and severe IUAs, who underwent hysteroscopic adhesiolysis. According to the postoperative placement of the ISB or FB, the cohort was divided into the ISB group and the FB group. Read More

J Obstet Gynaecol Can 2018 Dec 6. Epub 2018 Dec 6.

School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON; Department of Obstetrics, Gynecology, and Newborn Care, Ottawa Hospital, Ottawa, ON.

Traditionally, hysteroscopy has been performed in the main operating room with the patient under general anaesthesia. Hysteroscopy performed in an office setting avoids the risks of general anaesthesia. The aim of this review was to evaluate the effectiveness of outpatient hysteroscopy compared with hysteroscopy performed in the operating room to diagnose and/or treat intrauterine pathology. Read More

J Minim Invasive Gynecol 2018 Dec 7. Epub 2018 Dec 7.

Department of Women's Health and Territorial Medicine (Dr. De Angelis), University of Rome "La Sapienza", Rome, Italy.

Study Objective: To compare the effectiveness and safety of different techniques of hysteroscopic polypectomy.

Design: Multicenter, prospective observational trial (Canadian Task Force classification II-2).

Setting: Nineteen Italian gynecologic departments (university-affiliated or public hospitals). Read More

Cochrane Database Syst Rev 2018 12 5;12:CD009461. Epub 2018 Dec 5.

Academic Centre for General Practice, Cochrane Belgium, Kapucijnenvoer 33, blok J bus 7001, Leuven, Belgium, 3000.

Background: Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are present in 10% to 15% of women seeking treatment for subfertility.

Objectives: To assess the effects of the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions suspected on ultrasound, hysterosalpingography, diagnostic hysteroscopy or any combination of these methods in women with otherwise unexplained subfertility or prior to intrauterine insemination (IUI), in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI).

Search Methods: We searched the following databases from their inception to 16 April 2018; The Cochrane Gynaecology and Fertility Group Specialised Register, the Cochrane Central Register of Studies Online, ; MEDLINE, Embase , CINAHL , and other electronic sources of trials including trial registers, sources of unpublished literature, and reference lists. Read More

Arch Gynecol Obstet 2018 Dec 5. Epub 2018 Dec 5.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Shuaifuyuan No 1, Dongcheng District, Beijing, China.

Objective: To investigate the incidence and predictors of gynecologic malignancies among postmenopausal patients with endometrial fluid collection (EFC).

Methods: All patients with EFC diagnosed by transvaginal sonography (TVS) were retrospectively reviewed if they had undergone biopsy of the endometrium from January 2008 to January 2016 in a tertiary teaching hospital. Follow-up ended in June 2017. Read More

J Obstet Gynaecol Res 2018 Dec 2. Epub 2018 Dec 2.

2nd Unit of Obstetrics and Gynecology, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy.

Aim: This retrospective multicenter study was carried out to evaluate feasibility, effectiveness and patient acceptability of a small diameter hysteroscopic tissue removal system in the treatment of large endometrial polyps (≥20 mm), usually not removed in an office setting.

Methods: Hundred and forty-six women with a single greater than 10-mm diameter polyp considered for polypectomy between April 2016 and August 2017. Sixty-five of these patients had a polyp size greater than 20 mm. Read More

Fertil Steril 2018 Dec;110(7):1408-1409

Department of Obstetrics and Gynecology, BC Women's Hospital and Health Centre, University of British Columbia, Vancouver, British Columbia, Canada.

Objective: To introduce and demonstrate an approach to the hysteroscopic removal of retained intrauterine devices (IUDs) in pregnancy. Pregnancy risks associated with retained IUDs are also discussed, specifically spontaneous abortion and preterm labor.

Design: A step-by-step explanation of the procedure with surgical video footage. Read More

Fertil Steril 2018 Dec;110(7):1231-1238

Department of Obstetrics and Gynecology, Free University Medical Center, Amsterdam, The Netherlands.

Objective: To examine whether intrauterine application of auto-cross-linked hyaluronic acid (ACP) gel after dilation and curettage (D&C) improves reproductive performance.

Design: Multicenter prospective randomized trial.

Setting: One university and seven university-affiliated teaching hospitals. Read More

Georgian Med News 2018 Oct(283):19-26

Institute of Pediatrics, Obstetrics and Gynecology named E.M. Lukyanova of the NAS of Ukraine.

The aim of the study is to improve the diagnostic approach in assessing the state of the endometrium with the help of ultrasonic endometrial diagnostics in accordance with the IETА criteria in combination with three-dimensional Doppler indices, calculating the volume of the endometrium, and the 3D reconstruction in postmenopausal women. 167 postmenopausal women underwent a 2D pelvic ultrasound examination and a combined three-dimensional complex pelvic ultrasound examination that included calculation of the volume of the endometrium, three-dimensional dopplerometric indices (vascularization index, blood flow index and vascularization ratio), and 3D-reconstruction mode. In the second stage, the patients underwent hysteroscopy/endometrial bipyroscopy with morphological evaluation of tissue samples, which retrospectively performed analysis of echographic and dopplerometric criteria in patients with benign changes in the endometrium and their comparison with atrophic endometrium. Read More

Pain Res Treat 2018 1;2018:9368298. Epub 2018 Nov 1.

Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand.

Abnormal uterine bleeding in women aged 35 years or over is an important clinical sign of many gynecological conditions. The diagnoses of these conditions require the pathological report of the endometrial tissue. Outpatient-based endometrial biopsy is an excellent option compared to standard fractional uterine curettage or hysteroscopy with endometrial biopsy in providing a definite diagnosis for abnormal uterine bleeding as it is less painful and does not require high potency anesthesia. Read More

Facts Views Vis Obgyn 2018 Mar;10(1):21-27

European Academy of Gynaecological Surgery, 3000 Leuven, Belgium.

In order to offer our patients, the "state of the art" treatment in gynaecology, we need a structured teaching program for trainees concerning the gynaecological skills. In recent years, training and education in endoscopic surgery has been critically reviewed. Clinicians, both surgeons as gynaecologists who perform endoscopic surgery without proper training of the specific psychomotor skills, are at higher risk to increased patient morbidity and mortality. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Jan 6;232:40-45. Epub 2018 Nov 6.

Department of Gynecology, Institut Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine-University of Barcelona, Barcelona, Spain. Electronic address:

Objective: Ulipristal acetate (UPA) is a progesterone receptor modulator (PRM) agent that has shown benefits in women with symptomatic uterine fibroids. However, its effects on the endometrium are complex and not fully understood. We describe exploratory findings on macroscopic observation of the endometrium at transvaginal sonography (TVS) and hysteroscopy. Read More