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Am J Obstet Gynecol 2019 Feb 12. Epub 2019 Feb 12.

Department of Obstetrics and Gynecology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea. Electronic address:

Background: Premenopausal hysterectomy is associated with a decreased ovarian reserve, follicular atresia, and subsequently reduced long-term estrogen secretion. Therefore, women who undergo hysterectomy will experience greater gradual bone mineral loss than women with an intact uterus and have an increased risk of osteoporosis.

Objective: This study aimed to evaluate the association between hysterectomy without/with bilateral oophorectomy (BO) and the occurrence of osteoporosis using a national sample cohort from South Korea. Read More

Rech Soins Infirm 2019 Jan;135(4):83-90

Hysterectomies are often linked to benign pathologies, but they are nevertheless the cause of anxiety and lead to significant physiological and psychological changes for these women. The uterus, as a symbol of femininity for women, has a unique meaning in relation to its reproductive function and its role in sexuality. Given this fact, does conversational hypnosis-used when a patient arrives at the hospital-have an impact on the pre- and postoperative anxiety of patients hospitalized for gynecological surgery in the form of a hysterectomy? To answer this question, a pilot study of comparative monocentric feasibility was performed with two parallel groups of 10 patients in 2014. Read More

Womens Midlife Health 2018 15;4. Epub 2018 Jan 15.

2Research Centre for Generational Health and Ageing, The University of Newcastle, Callaghan, NSW Australia.

Background: Age at natural menopause (ANM) is considered as a biologic marker of health and ageing. The relationship between intimate partner violence (IPV) and ANM is currently unknown, and whether smoking plays a role in this relationship is unclear. The aim of this study was to examine the association between IPV and ANM and to quantify the effect mediated through smoking. Read More

Int J Gynecol Cancer 2019 Feb 13. Epub 2019 Feb 13.

Oncological surgery, Clinica Astorga, Envigado, Colombia.

Background: Radical trachelectomy is considered a viable option for fertility preservation in patients with low-risk, early-stage cervical cancer. Standard approaches include laparotomy or minimally invasive surgery when performing radical trachelectomy.

Primary Objective: To compare disease-free survival between patients with FIGO (2009) stage IA2 or IB1 (≤2cm) cervical cancer who underwent open versus minimally invasive (laparoscopic or robotic) radical trachelectomy. Read More

Acta Obstet Gynecol Scand 2019 Feb 14. Epub 2019 Feb 14.

Norwegian National Advisory Unit on Women's Health, Rikshospitalet Oslo University Hospital, Oslo, Norway.

Introduction: Complete uterine rupture, a rare peripartum complication, is often associated with a catastrophic outcome for both mother and child. However, few studies have investigated large data sets to evaluate maternal outcomes after complete ruptures, particularly in unscarred uteri. This paucity of studies is partly due to the rarity of both the event and the serious outcomes, such as peripartum hysterectomy and maternal death. Read More

BMJ Open 2019 Feb 12;9(2):e022259. Epub 2019 Feb 12.

Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Objectives: To conduct a systematic review of qualitative studies which explore health professionals' experiences of and perspectives on the enhanced recovery after surgery (ERAS) pathway.

Design: Systematic review of qualitative literature using a qualitative content analysis. Literature includes the experiences and views of a wide range of multidisciplinary team and allied health professional staff, to incorporate a diverse range of clinical and professional perspectives. Read More

Ann Surg Oncol 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, China.

Background: Little data exist about the impact of dissection methods on bladder function during nerve-sparing radical hysterectomy (NSRH). This randomized controlled trial compared the urodynamic and survival outcomes of different methods dissecting the inferior hypogastric plexus (IHP) during laparoscopic NSRH.

Methods: Eligible patients presenting with stage IB cervical cancer from 9 May 2013 to 27 October 2015 were randomized at a ratio of 1:1 and subjected to waterjet (study group) or traditional blunt (control group) dissection of the IHP for laparoscopic type C radical hysterectomy. Read More

Ginekol Pol 2019 ;90(1):20-30

Department of Gynecology, Gynecologic Oncology and Gynecologic Endocrinology, Medical University of Gdansk, Poland.

Objectives: To assess the significance of pathologic ultrastaging (PU) of sentinel (SLN) and non-sentinel (nSLN) lymph nodes (LNs) and the influence on cancer staging in patients with International Federation of Gynecology and Obstetrics (FIGO) stage IA2-IB1 cervical cancer.

Material And Methods: A retrospective study was conducted with 54 patients divided into two equal-sized groups. In test group (n1), at least one SLN/patient was detected with blue dye. Read More

Pathologe 2019 Feb;40(1):21-35

Pathologisches Institut, Medizinische Fakultät, Ludwig-Maximilians-Universität München, München, Deutschland.

The present article summarises the relevant aspects of the S3 guidelines on endometrioid carcinomas. The recommendations include the processing rules of fractional currettings as well as for hysterectomy specimens and lymph node resections (including sentinel lymph nodes). Besides practical aspects, the guidelines consider the needs of the clinicians for appropriate surgical and radiotherapeutic treatment of the patients. Read More

Mymensingh Med J 2019 Jan;28(1):206-213

Dr Nasrin Akhter, Associate Professor, Department of Obstetrics & Gynecology, Dhaka Medical College, Dhaka, Bangladesh.

Genitourinary fistula is a psychophysiosocial distress that results in prolonged labour. Gradually, it has become a public health issue globally with advancing of its incidence day by day. A handsome number of mothers are also suffering in Bangladesh from genitourinary fistula. Read More

Clin Radiol 2019 Feb 9. Epub 2019 Feb 9.

Department of Clinical Pharmacy, Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences, Tehran, Iran. Electronic address:

Aim: To evaluate the efficacy and safety of the uterine artery embolisation (UAE) in combination with methotrexate (MTX) for conservative management of placental adhesive disorders.

Material And Methods: Patients with placental adhesive disorders (including accreta, increta, and percreta lesions) that were treated with UAE in combination with MTX were identified and were followed prospectively for outcomes including uterine preservation and complications.

Results: Twenty-six patients were identified who had the diagnosis of abnormal placenta implantation during this study. Read More

J Natl Cancer Inst 2019 Feb 11. Epub 2019 Feb 11.

Population Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.

Background: Recent studies have called into question the long-held belief that hysterectomy without oophorectomy protects against ovarian cancer. This population-based longitudinal record-linkage study aimed to explore this relationship, overall and by age at hysterectomy, time period, surgery type, and indication for hysterectomy.

Methods: We followed the female adult Western Australian population (837,942 women) across a 27-year period using linked electoral, hospital, births, deaths, and cancer records. Read More

Horm Mol Biol Clin Investig 2019 Feb 6. Epub 2019 Feb 6.

Department of Perinatology, Obstetrics and Gynecology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia.

Background Severe forms of adenomyosis are a serious gynecological problem. In most cases, conservative treatment of this pathology is unsuccessful. Adenomyomectomy by Osada's approach seems to be the most promising solution. Read More

Cochrane Database Syst Rev 2019 Feb 12;2:CD012828. Epub 2019 Feb 12.

Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, 123 Mitraparb Road, Amphur Muang, Khon Kaen, Thailand, 40002.

Background: Radical hysterectomy is one of the standard treatments for stage Ia2 to IIa cervical cancer. Bladder dysfunction caused by disruption of the pelvic autonomic nerves is a common complication following standard radical hysterectomy and can affect quality of life significantly. Nerve-sparing radical hysterectomy is a modified radical hysterectomy, developed to permit resection of oncologically relevant tissues surrounding the cervical lesion, while preserving the pelvic autonomic nerves. Read More

Diagn Pathol 2019 Feb 11;14(1):17. Epub 2019 Feb 11.

Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan.

Background: Retroperitoneal high-grade serous carcinoma (HGSC) is extremely rare and the origin remains unclear. We present a case of retroperitoneal HGSC and coexisting serous tubal intraepithelial carcinoma (STIC), which is considered as the main origin of ovarian HGSC. We reviewed the available literature and discussed about the origin of this rare disease. Read More

Cuad Bioet 2019 Jan-Apr;30(98):67-76

Academia Alphonsiana Roma. Italia.

The article presents a rare case of uterine rupture at the 19th week of gestation, in the presence of a scar after a caesarean section practiced two years earlier. The fetus was pulled out alive, but given the gestational age, died within a few minutes. The uterus was preserved, but the woman was advised to proceed with tubal ligation and, in any case, to absolutely avoid a new pregnancy. Read More

Obstet Gynecol 2019 Feb 4. Epub 2019 Feb 4.

Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, the Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, and the University of Cincinnati Department of Pediatrics, Cincinnati, Ohio.

Objective: In 2014, the Society for Maternal-Fetal Medicine, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the American Academy of Pediatrics, and the American College of Obstetricians and Gynecologists published an executive summary of a joint workshop to establish obstetric interventions to be considered for periviable births. We sought to evaluate changes in practice patterns since the publication of these guidelines.

Methods: We conducted a population-based cohort study of all singleton live births delivered between 22 0/7 and 23 6/7 weeks of gestation in the United States within two time epochs: pre-executive summary (Epoch 1: 2012-2013) and post-executive summary (Epoch 2: 2015-2016) guideline release. Read More

Obstet Gynecol 2019 Feb 4. Epub 2019 Feb 4.

Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, and Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, Tennessee.

Objective: To estimate the absolute and relative risk of venous thromboembolism (VTE) among women who initiate depot medroxyprogesterone acetate (DMPA) immediately postpartum compared with those who do not initiate hormonal contraception.

Methods: The IBM MarketScan Commercial Claims and Encounters databases were used to identify delivery hospitalizations among women aged 15-44 years during 2005 through 2014. Diagnosis, procedure, and drug codes were used to identify contraception, VTE, and potential confounding chronic or pregnancy-related conditions. Read More

Int Urogynecol J 2019 Feb 11. Epub 2019 Feb 11.

Department of Obstetrics and Gynecology, University of Texas Southwestern, Dallas, TX, USA.

Introduction And Hypothesis: We aimed to systematically review the literature on pelvic organ prolapse (POP) surgery with uterine preservation (hysteropexy). We hypothesized that different hysteropexy surgeries would have similar POP outcomes but varying adverse event (AE) rates.

Methods: MEDLINE, Cochrane, and clinicaltrials. Read More

J Gynecol Oncol 2019 Jan 3. Epub 2019 Jan 3.

Department of Obstetrics and Gynecology, Kyung Hee University Hospital at Gangdong, Seoul, Korea.

J Gynecol Oncol 2018 Nov 27. Epub 2018 Nov 27.

Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy.

Objectives: Nerve-sparing radical hysterectomy has been implemented in order to reduce pelvic floor dysfunctions in women undergoing radical surgery for cervical cancer. Here, we aimed to investigate if the adoption of laparoscopic surgery impacts on patients' outcomes.

Methods: Data of consecutive patients affected by cervical cancer who had laparoscopic nerve-sparing radical hysterectomy were matched 1:1 with an historical cohort of patients undergoing open procedure. Read More

J Gynecol Oncol 2018 Nov 7. Epub 2018 Nov 7.

Department of Radiation Oncology, Ajou University School of Medicine, Suwon, Korea.

Objective: This longitudinal study aimed to analyze the prevalence of mental disorders in endometrial cancer survivors in South Korea.

Methods: We assessed mental disorders in a nationwide cohort of 8,155 patients who were diagnosed with endometrial cancer between January 1, 2010, and December 31, 2014. We categorized the prevalence of mental disorders based on age and time of diagnosis. Read More

Acta Obstet Gynecol Scand 2019 Feb 10. Epub 2019 Feb 10.

OLVG locatie OostAmsterdam, Netherlands.

We wish to thank Dr. Matsubara et al. for their valuable response on our Editorial that deals with the important topic whether all residents still need to learn to perform abdominal hysterectomy. Read More

J Minim Invasive Gynecol 2019 Feb 7. Epub 2019 Feb 7.

Department of Gynecology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.

Study Objective: This study aimed to determine if it is possible and safe to obtain adenomyosis tissue in vivo without removing the uterus, in order to use those for further molecular investigations of adenomyosis, which would allow investigating the pathogenesis of the disease.

Study Design: Prospective cohort study (Canadian Task Force classification II-2) SETTING: A university hospital PATIENTS: 81 premenopausal women scheduled for a hysterectomy due to various benign indications were included.

Interventions: Ultrasound-guided, transvaginal uterine core biopsy samples were obtained and the required time was registered. Read More

J Minim Invasive Gynecol 2019 Feb 5. Epub 2019 Feb 5.

Department of Obstetrics and Gynecology Christiana Care Hospital System, Newark, DE.

Int Braz J Urol 2019 Jan 25;45. Epub 2019 Jan 25.

Department of Gynae-Oncology, Asian Cancer Institute, Mumbai, India.

We demonstrate robot assisted radical nephrectomy with hysterectomy in the same sitting position followed by specimen retrieval per vagina (NOSE- Natural Orifice Specimen Extraction) A 36 year old female P2L2, presented with long standing dysmenorrhoea. Abdominal sonography detected incidental large left renal mass with a large fundal fibroid. CT scan revealed 8cmx8cm mass arising from mid and lower zone of the left kidney without vascular invasion and lymphadenopathy with a large fundal fibroid. Read More

J Vis Exp 2019 Jan 17(143). Epub 2019 Jan 17.

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, China; Shenzhen Key Laboratory of Gynecological Diagnostic Technology Research, China;

Uterine fibroids are common benign tumors in the female reproductive system. A hysterectomy is the most effective treatment for symptomatic fibroids. For patients desiring pregnancy, laparoscopic intracapsular myomectomy (LM) is an alternative surgery option. Read More

Eur J Surg Oncol 2019 Jan 30. Epub 2019 Jan 30.

Department of Obstetrics and Gynecology, University Hospital of Bern and University of Berne, Berne, Switzerland.

Background: To evaluate sensitivity, false negative rate and negative predictive value of the combination of sentinel lymph node (SLN) mapping and frozen section (FS) in triaging cervical cancer patients to a definitive chemo-radiotherapy.

Methods: A retrospective analysis of patients with histologically proven cervical cancer undergoing laparoscopic SLN mapping and frozen section of the SLNs followed by a completion radical hysterectomy, pelvic and/or paraarotic lymphadenectomy. Sensitivity, false negative rate and negative predictive value of the SLN mapping, of the frozen section and of the combination of the two in identifying micro- and macrometastases were calculated. Read More

J Int Med Res 2019 Feb 8:300060518821824. Epub 2019 Feb 8.

1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

A uterine tumor resembling an ovarian sex cord tumor (UTROSCT) is a rare type of neoplasm that is almost thoroughly differentiated towards ovarian sex cord elements. Because of abnormal uterine bleeding, a 64-year-old postmenopausal woman received total abdominal hysterectomy with bilateral salpingo-oophorectomy. Under a microscope, the tumor cells showed an anastomosing fascicular and trabecular pattern with a reticular architecture. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Jan 30;234:218-222. Epub 2019 Jan 30.

Division of Gynecologic Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Division of Gynecology, San Carlo di Nancy Hospital, Rome, Italy.

Objective: To investigate the safety, feasibility and oncological adequacy of the Percutaneous Surgical System - PSS in a consecutive series of low-risk endometrial cancer staging.

Study Design: From May 2015 to April 2017, we prospectively performed 30 consecutive percutaneous staging for low/intermediate risk endometrial cancer (FIGO stage IA G1-G2, IB G1-G2, IA G3). All patients were divided in two different groups on the basis of surgical procedure received: Group A included patients submitted to radical Class A hysterectomy and bilateral salpingo-oophorectomy; Group B concerned patients that received a lymph nodal assessment also. Read More

J Matern Fetal Neonatal Med 2019 Feb 7:1-2. Epub 2019 Feb 7.

a Department of Obstetrics and Gynecology , Jichi Medical University , 3311-1 Yakushiji , Shimotsuke , Tochigi , Japan.

Rev Med Chil 2018 Sep;146(9):1074-1078

Sección Genética Hospital Clínico, Universidad de Chile, Santiago, Chile.

We report a 51-year-old female who had a first episode of thrombocytopenia at 23 years of age during a pregnancy. At the age of fifty, a hysterectomy was indicated due to a metrorrhagia: a platelet count of 21,000/ul was detected. She was treated with eltrombopag with a good response. Read More

J Med Internet Res 2019 Feb 6;21(2):e9938. Epub 2019 Feb 6.

Amsterdam Public Health Research Institute, Department of Occupational and Public Health, VU University Medical Center, Amsterdam, Netherlands.

Background: Support for guiding and monitoring postoperative recovery and resumption of activities is usually not provided to patients after discharge from the hospital. Therefore, a perioperative electronic health (eHealth) intervention ("ikherstel" intervention or "I recover" intervention) was developed to empower gynecological patients during the perioperative period. This eHealth intervention requires a need for further development for patients who will undergo various types of general surgical and gynecological procedures. Read More

Gynecol Oncol Rep 2019 Feb 16;27:69-71. Epub 2019 Jan 16.

Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH 43210, United States.

•Extreme obesity may preclude patients from primary surgical management of endometrial cancer.•Bariatric surgery is a safe and effective method of rapid weight loss in patients with extreme obesity.•Delayed hysterectomy, after weight loss from bariatric surgery, is an option in select patients with endometrial cancer. Read More

J Feline Med Surg 2019 Feb 5:1098612X19826700. Epub 2019 Feb 5.

2 Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.

Objectives: This study sought to determine if bupivacaine targeted at specific, potentially painful sites could enhance postoperative analgesia in routine feline ovariohysterectomies. A secondary objective was to assess the utility of multiple acute pain scales for cats in a high-volume surgery setting.

Methods: Two hundred and twelve cats were included in a prospective, randomized, double-blinded, placebo-controlled clinical trial. Read More

Eur Rev Med Pharmacol Sci 2019 Jan;23(2):892-902

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy.

Women suffering from Uterine Factor Infertility (UFI) arising from congenital conditions (e.g., Rokitansky-Kuster-Hauser syndrome) or hysterectomy can fulfill their wish to achieve motherhood only by resorting to surrogacy, which is, however, banned in most countries. Read More

Eur J Microbiol Immunol (Bp) 2018 Dec 15;8(4):155-158. Epub 2018 Nov 15.

Hospital General, Secretaría de Salud, Avenida 5 de febrero y Norman Fuentes, 34000 Durango, Mexico.

We determined the association between having a history of surgery and the seroreactivity to An age- and gender-matched case-control study of 391 subjects with a history of surgery and 391 subjects without this history was performed. Sera of subjects were analyzed for detection of anti- immunoglobulin G (IgG) and M (IgM) antibodies using enzyme-linked immunoassays. Anti- IgG antibodies were found in 25 (6. Read More

SAGE Open Med Case Rep 2019 16;7:2050313X18823901. Epub 2019 Jan 16.

Department of Pathology, School of Medicine, Dongsan Medical Center, Keimyung University, Daegu, Korea.

A 73-year-old woman was referred to the pulmonology department for abnormal findings on chest computed tomography. She had undergone a laparoscopic staging operation including a hysterectomy, bilateral salpingo-oophorectomy, bilateral pelvic node and para-aortic node dissection, and concurrent chemo-radiation therapy for endometrial serous carcinoma stage IIIc cancer 15 months earlier. A follow-up chest computed tomography after the chemotherapy showed that the right lower lobe bronchus was obstructed, and it was necessary to differentiate a primary lung malignancy from a metastasis and secretion. Read More

Int J Gynecol Cancer 2019 Feb 18;29(2):312-319. Epub 2019 Jan 18.

Department of Gynecology and Obstetrics, University of Parma, Parma, Italy.

Objective: To determine the incidence of long term lymphadenectomy complications in primary surgery for endometrial cancer and to elucidate risk factors for these complications.

Methods: A retrospective chart review was carried out for all patients with endometrial cancer managed at Parma University Hospital Unit of Gynecology and Obstetrics between 2010 and 2016. Inclusion criteria were surgical procedure including hysterectomy and lymphadenectomy (pelvic or pelvic and aortic). Read More

Gynecol Oncol 2019 Feb 2. Epub 2019 Feb 2.

The Ohio State University, James Cancer Hospital, Division of Gynecologic Oncology, 320 West 10(th) Avenue, Columbus, OH 43210, USA. Electronic address:

Objective: The impact of pathologic features of a cone biopsy on the management of women with early stage cervical cancer is understudied. Our objective was to evaluate the additive value of pathologic features of a cone biopsy toward identifying patients with high risk tumors for which adjuvant therapy may be indicated.

Methods: Patients with early stage cervical cancer undergoing a conization followed by radical hysterectomy from 1995 to 2016 were retrospectively identified. Read More

Eur Urol 2019 Feb 1. Epub 2019 Feb 1.

Essen University Hospital, University of Duisburg-Essen, Essen, Germany.

J Vasc Interv Radiol 2019 Feb;30(2):195-202.e1

Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, Korea.

Purpose: To compare the efficacy of lymph node (LN) embolization using N-butyl cyanoacrylate versus ethanol sclerotherapy in the management of symptomatic postoperative pelvic lymphorrhea.

Materials And Methods: Thirty-three patients with 40 instances of symptomatic postoperative lymphorrhea were treated with either LN embolization or sclerotherapy at Seoul National University Hospital from January 2009 to July 2017 and were retrospectively included (LN embolization group: 24 lymphoceles of 19 patients, mean age of 59.29 years; sclerotherapy group: 16 lymphoceles of 14 patients, mean age of 60. Read More

Z Geburtshilfe Neonatol 2019 Feb 4. Epub 2019 Feb 4.

Universitätsklinik für Frauenheilkunde, Geburtshilfe und Reproduktionsmedizin, Universitätsklinikum Magdeburg, Magdeburg.

An inverted uterus is defined as the eversion of the uterus into the vagina. It is a very rare event but has to be treated as an emergency. A woman with an inverted uterus is in serious danger of developing atony with high blood loss in a short time. Read More

Am J Obstet Gynecol 2019 Feb 1. Epub 2019 Feb 1.

Department of Obstetrics, Rigshospitalet, University of Copenhagen, Denmark.

Objective: The objective of this study was to evaluate the prevalence of placenta accreta spectrum in general population studies and the main maternal outcomes at delivery.

Study Design: Data sources: We searched PubMed, Google Scholar, clinicalTrials.gov and MEDLINE between 1982 and 2018. Read More

Acta Obstet Gynecol Scand 2019 Feb 3. Epub 2019 Feb 3.

Gynecology and Obstetrics Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.

Introduction: Atypical polypoid adenomyoma (APA) is an uncommon uterine lesion, which can coexist with endometrial atypical hyperplasia and/or cancer. APA affects premenopausal women in most cases, but it shows high recurrence rate if conservatively treated. To date, the management of patients is based on low quality evidence and not standardized. Read More

Intern Med 2019 Feb 1. Epub 2019 Feb 1.

Department of Pathology, Japanese Red Cross Ishinomaki Hospital, Japan.

We herein report a very rare case of spontaneous regression of recurrent undifferentiated carcinoma of the endometrium. An 80-year-old woman had undergone total hysterectomy with bilateral adnexectomy for undifferentiated carcinoma of the endometrium. The cancer recurred locally 10 months after surgery and then metastasized to the lung and liver. Read More

Best Pract Res Clin Obstet Gynaecol 2018 Dec 21. Epub 2018 Dec 21.

Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Absolute uterine factor infertility (AUFI), with uterine absence or presence of a non-functional uterus, was considered untreatable until 2014, when the first child was born after transplantation of a uterus from a postmenopausal woman to a woman of fertile age who was born with no uterus, as a part of the Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. Concerning gynaecological cancer, AUFI may occur after hysterectomy for malignancy or after surgery/radiation that will preserve the uterus but causing non-functionality in terms of future implantation and pregnancy. This review summarises the research preparations that paved the way for the clinical introduction of uterus transplantation (UTx) as a treatment for AUFI. Read More

J Glob Oncol 2019 Jan(5):1-7

4 Massachusetts General Hospital, Boston, MA.

Purpose: The aim of the study was to evaluate the efficacy of hysterectomy in the control of pelvic disease in patients with post-irradiated residual cervical cancer.

Patients And Methods: Forty patients were treated at either National Institute of Cancer Research and Hospital (NICRH) or Delta Cancer Hospital in Dhaka, Bangladesh, with International Federation of Gynecology and Obstetrics stage IIB to IIIB disease with residual disease after the following: either concurrent chemoradiation with or without brachytherapy, induction chemotherapy and external-beam radiotherapy (EBRT) with or without brachytherapy, or only EBRT. Patients were treated by either radical hysterectomy or extrafascial hysterectomy. Read More

JAMA Netw Open 2019 Feb 1;2(2):e187673. Epub 2019 Feb 1.

Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Cedars-Sinai Medical Center, Los Angeles, California.

Importance: Early postoperative ambulation is vital to minimizing length of stay (LOS), but few hospitals objectively measure ambulation to predict outcomes. Wearable activity monitors have the potential to transform assessment of postoperative ambulation, but key implementation data, including whether digitally monitored step count can identify patients at risk for poor efficiency outcomes, are lacking.

Objectives: To define the distribution of digitally measured daily step counts after major inpatient surgical procedures, to assess the accuracy of physician assessment and ordering of ambulation, and to quantify the association of digitally measured step count with LOS. Read More

Female Pelvic Med Reconstr Surg 2019 Jan 30. Epub 2019 Jan 30.

Objective(s): Most surgeons recommend restriction of activities after minimally invasive gynecologic and pelvic reconstructive surgery. The goal of this study was to identify and assess the postoperative guidelines gynecologists and urogynecologists provide their patients.

Methods: This was a cross-sectional study of physicians at a national gynecology conference in March 2018. Read More