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    400 results match your criteria Hypothyroidism and Myxedema Coma

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    Effects of Long-Term Combination LT4 and LT3 Therapy for Improving Hypothyroidism and Overall Quality of Life.
    South Med J 2018 Jun;111(6):363-369
    From the Departments of Internal Medicine, Research and Biostatistical Analysis, and Endocrinology, UPMC Pinnacle Health, Harrisburg, Pennsylvania.
    Objectives: Hypothyroidism results in decreased mood and neurocognition, weight gain, fatigue, and many other undesirable symptoms. The American Association of Clinical Endocrinologists, the American Thyroid Association (ATA), and The Endocrine Society recommend levothyroxine (LT4) monotherapy as the treatment for hypothyroidism; however, after years of monotherapy, some patients continue to experience impaired quality of life. Combination LT4 and synthetic liothyronine (LT3) therapy or the use of desiccated thyroid extract (DTE), has not been suggested for this indication based on short-duration studies with no significant benefits. Read More

    Amiodarone induced myxedema coma: Two case reports and literature review.
    Heart Lung 2018 May 21. Epub 2018 May 21.
    Department of Cardiology, New York Medical College, St. Joseph Medical Center, 703 Main Street, Paterson, NJ 07503, USA.
    Amiodarone is a benzofuran derivative that contains 37% iodine by weight and is structurally similar to the thyroid hormones. Amiodarone has a complex effect on the thyroid gland, ranging from abnormalities of thyroid function tests to overt thyroid dysfunction, with either thyrotoxicosis or hypothyroidism. Myxedema coma secondary to amiodarone use has been rarely reported in the literature. Read More

    Myxedema Coma due to Hashimoto Thyroiditis: A Rare but Real Presentation of Failure to Thrive in Infancy.
    Horm Res Paediatr 2018 May 4:1-5. Epub 2018 May 4.
    Background: Hashimoto thyroiditis (HT) is uncommon in infancy, and myxedema coma (MC) is even less common. While prior reports have documented these entities separately, to our knowledge, MC in combination with HT has not been reported before in this age group.

    Methods/results: A 10-month-old female presented with ptosis, lethargy, dysphagia, and failure to thrive (FTT). Read More

    Myxedema Coma.
    J Ayub Med Coll Abbottabad 2018 Jan-Mar;30(1):119-120
    Diabetes and Endocrinology, University Hospital of Hartlepool, UK.
    Myxedema may be the first presentation of patients with undiagnosed hypothyroidism. Definitive management is with thyroid hormone but supportive measures, identification and treatment of precipitating factors in an appropriately safe environment are vital. There is no consensus about preferred thyroid hormone regimen. Read More

    Management of concomitant metabolic encephalopathy and meningioma with vasogenic edema and impending herniation.
    Surg Neurol Int 2018 8;9:25. Epub 2018 Feb 8.
    Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, Illinois, USA.
    Background: Altered mental status describes impaired mental functioning ranging from confusion to coma and indicates an illness, either metabolic or structural in nature. Metabolic causes include hypothyroidism, hyperuremia, hypo/hyperglycemia, hypo/hypernatremia, and encephalopathy. The structural causes include tumors, brain hemorrhage, infection, and stroke. Read More

    Sudden cardiac arrest as a rare presentation of myxedema coma: case report.
    J Community Hosp Intern Med Perspect 2017 18;7(5):318-320. Epub 2017 Oct 18.
    Department of Pulmonary Medicine, Interfaith Medical Centre, Brooklyn, NY, USA.
    Myxedema coma is a decompensated hypothyroidism which occurs due to long-standing, undiagnosed, or untreated hypothyroidism. Untreated hypothyroidism is known to affect almost all organs including the heart. It is associated with a decrease in cardiac output, stroke volume due to decreased myocardial contractility, and an increase in systemic vascular resistance. Read More

    Split high-dose oral levothyroxine treatment as a successful therapy option in myxedema coma.
    Clin Case Rep 2017 Oct 8;5(10):1706-1711. Epub 2017 Sep 8.
    Division of Endocrinology and MetabolismDepartment of MedicineFaculty of Medicine Ramathibodi HospitalMahidol UniversityBangkok10400Thailand.
    High-dose intravenous thyroxine (T4) is the preferable treatment for myxedema coma. We describe the clinical course of a 69-year-old man who presented with myxedema coma and received oral levothyroxine (LT4) therapy (1 mg) in a split dose. This suggests split high-dose oral LT4 as a therapeutic option in myxedema coma. Read More

    Challenges in the Management of a Patient with Myxoedema Coma in Ghana: A Case Report.
    Ghana Med J 2017 Mar;51(1):39-42
    Neurology Unit, Department of Medicine and Therapeutics, School of Medicine and Dentistry, University of Ghana, PO Box GP 4236, Accra, Ghana.
    Myxoedema coma is a rare life-threatening disease, and it is essential that it is managed appropriately to reduce the associated high mortality. However, in the setting where efficient healthcare delivery is hampered by inadequacies, the management of such cases may pose a significant challenge. We present the case of a middle-aged woman diagnosed with myxoedema coma and severe hyponatremia. Read More

    [Thyroid emergencies : Thyroid storm and myxedema coma].
    Internist (Berl) 2017 Oct;58(10):1011-1019
    Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Marchioninistraße 15, 81377, München, Deutschland.
    Thyroid emergencies are rare life-threatening endocrine conditions resulting from either decompensated thyrotoxicosis (thyroid storm) or severe thyroid hormone deficiency (myxedema coma). Both conditions develop out of a long-standing undiagnosed or untreated hyper- or hypothyroidism, respectively, precipitated by an acute stress-associated event, such as infection, trauma, or surgery. Cardinal features of thyroid storm are myasthenia, cardiovascular symptoms, in particular tachycardia, as well as hyperthermia and central nervous system dysfunction. Read More

    [Myxedema coma].
    Medicina (B Aires) 2017 ;77(4):321-328
    Department of Medicine, Washington Hospital Center, Washington, DC, USA.
    Hypothyroidism is a frequently diagnosed and simply treated disease. If not recognised, however, in time it may develop into the most severe manifestation of hypothyroidism known as myxedema coma. The term "myxedema coma" is generally seen as misleading since most patients do not initially present in a coma. Read More

    Thoracentesis-reverting cardiac tamponade physiology in a patient with myxedema coma and large pleural effusion.
    Proc (Bayl Univ Med Cent) 2017 Jul;30(3):295-297
    Departments of Internal Medicine (Werlang) and Critical Care Medicine (Pimentel, Diaz-Gomez), Mayo Clinic, Jacksonville, Florida. Dr. Pimentel is currently at Irmandade Santa Casa de Misericordia, Porto Alegre, Brazil.
    A large pleural effusion causing cardiac tamponade physiology and severe hemodynamic compromise is an uncommon event. We report a case of a 53-year-old woman with severe hypothyroidism presenting with myxedema coma and refractory shock. Her hemodynamic status failed to respond to fluid resuscitation and vasopressors. Read More

    Myxedema coma: A case report of pediatric emergency care.
    Medicine (Baltimore) 2017 May;96(21):e6952
    aPediatric Critical Care Medicine, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine bDepartment of Pediatric Endocrinology/Genetics, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai Institute for Pediatric Research, Shanghai, China.
    Raionale: Myxedema coma (MC) is extremely rare but lethal in pediatric patients with hypothyroidism leading to altered mental status and hypothermia. But there is no clinical guideline for such cases.

    Patient Concerns: A 6-year-old Chinese girl presented with coma and hypothermia preceded by pneumonia. Read More

    Diagnosis of myxedema coma complicated by renal failure: a case report.
    Clin Case Rep 2017 Apr 21;5(4):399-402. Epub 2017 Feb 21.
    Department of General Medicine Himi Municipal Hospital Kanazawa Medical University 31-9 Saiwai-cho Himi Toyama Japan.
    Myxedema coma, caused by severe lack of thyroid hormone, is characterized by deterioration of mental status, hypothermia, hypotension, hyponatremia, and hypoventilation. We describe an 84-year-old woman who presented with renal failure and new onset severe hypothyroidism leading to challenges in the recognition of myxedema coma. Read More

    Clinical characteristics and outcomes of myxedema coma: Analysis of a national inpatient database in Japan.
    J Epidemiol 2017 Mar 5;27(3):117-122. Epub 2017 Jan 5.
    Department of General Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
    Background: Myxedema coma is a life-threatening and emergency presentation of hypothyroidism. However, the clinical features and outcomes of this condition have been poorly defined because of its rarity.

    Methods: We conducted a retrospective observational study of patients diagnosed with myxedema coma from July 2010 through March 2013 using a national inpatient database in Japan. Read More

    Myxedema Psychosis in a Patient With Undiagnosed Hashimoto Thyroiditis.
    J Am Osteopath Assoc 2017 Jan;117(1):50-54
    Myxedema psychosis is uncommon in patients with primary hypothyroidism. Most often, this disease state can be found in patients with Hashimoto thyroiditis or after total thyroidectomy. Chronic hypothyroidism can lead to an insidious onset of psychiatric symptoms in patients, such as dementia, delirium, psychosis, hallucinations, and coma. Read More

    An Atypical Case of Myxedema Coma with Concomitant Nonconvulsive Seizure.
    Case Rep Crit Care 2016 30;2016:3438080. Epub 2016 Oct 30.
    Pulmonary and Critical Care, St. John's Riverside Hospital, 967 N. Broadway, Yonkers, NY 10701, USA.
    Hypothyroidism is a prevalent condition in the general population that is treatable with appropriately dosed thyroid hormone replacement medication. Infrequently, patients will present with myxedema coma, characterized by hypothermia, hypotension, bradycardia, and altered mental status in the setting of severe hypothyroidism. Myxedema coma has also been known to manifest in a number of unusual and dangerous forms. Read More

    Impending myxedema coma as the initial presentation of lung cancer.
    J Formos Med Assoc 2017 06 4;116(6):488-489. Epub 2016 Nov 4.
    Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

    Myxedema Coma Secondary to Central Hypothyroidism: A Rare but Real Cause of Altered Mental Status in Pediatrics.
    Horm Res Paediatr 2017 16;87(5):350-353. Epub 2016 Sep 16.
    Section of Endocrinology, Metabolism and Diabetes, Nationwide Children's Hospital, Columbus, Ohio, USA.
    Background: Myxedema coma (MC), a medical emergency defined as severe hypothyroidism leading to altered mental status, is more common in older women with hypothyroidism.

    Methods/results: A 7-year-old Caucasian male with chromosome 1q deletion presented with altered mental status preceded by milestone regression. His presenting labs results were: thyroid-stimulating hormone (TSH) 0. Read More

    Thyroid Emergencies.
    J Infus Nurs 2016 Sep-Oct;39(5):281-6
    Division of Endocrinology, David Geffen School of Medicine at UCLA, and the VA Greater Los Angeles Healthcare System, Los Angeles, California. Angela M. Leung, MD, MSc, is an assistant clinical professor of medicine in the Division of Endocrinology at the David Geffen School of Medicine at the University of California, Los Angeles, and the VA Greater Los Angeles Healthcare System, both in Los Angeles, California.
    Myxedema coma and thyroid storm are thyroid emergencies associated with increased mortality. Prompt recognition of these states-which represent the severe, life-threatening conditions of extremely reduced or elevated circulating thyroid hormone concentrations, respectively-is necessary to initiate treatment. Management of myxedema coma and thyroid storm requires both medical and supportive therapies and should be treated in an intensive care unit setting. Read More

    Pediatric Patient With Altered Mental Status and Hypoxemia: Case Report.
    Pediatr Emerg Care 2017 Jul;33(7):486-488
    From the *Department of Pediatrics, University of Pittsburgh School of Medicine; †Department of Pediatrics, Children's Hospital of Pittsburgh; ‡Division of Pediatric Endocrinology, Department of Pediatrics, University of Pittsburgh School of Medicine; and §Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA.
    Childhood cases of myxedema coma are extremely rare. We report a case of a 5-year-old girl transferred to a tertiary care pediatric emergency department with hypoxemia and altered mental status and diagnosed with severe hypothyroidism and myxedema coma in the setting of acute influenza infection. Although it is rare, myxedema coma must remain in the differential diagnosis for altered mental status and organ dysfunction in the pediatric population. Read More

    A rabbit model of fatal hypothyroidism mimicking "myxedema coma" established by microscopic total thyroidectomy.
    Endocr J 2016 Jun 26;63(6):523-32. Epub 2016 Mar 26.
    Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.
    Myxedema coma (MC) is a life-threatening endocrine crisis caused by severe hypothyroidism. However, validated diagnostic criteria and treatment guidelines for MC have not been established owing to its rarity. Therefore, a valid animal model is required to investigate the pathologic and therapeutic aspects of MC. Read More

    Precision Medicine Comes to Thyroidology.
    J Clin Endocrinol Metab 2016 Mar 23;101(3):799-803. Epub 2016 Feb 23.
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-0003.
    Context: The broad spectrum of thyroid disease severity--from subclinical hypothyroidism to myxedema coma, subclinical thyrotoxicosis to thyroid storm, and microscopic papillary to anaplastic cancers--has always demanded that clinicians individualize their management of thyroid patients. Deepening knowledge of thyroid pathophysiology along with advances in diagnostic, prognostic, and therapeutic technologies applicable to thyroid diseases position this field to ride the wave of precision medicine in the decade ahead. Read More

    Myxoedema coma in the setting of hyperglycaemic hyperosmolar state.
    BMJ Case Rep 2016 Jan 11;2016. Epub 2016 Jan 11.
    Anaesthesia and Critical Care, Tameside Hospital NHS Foundation Trust, Lancashire, UK.
    Decompensated hypothyroidism is a rare endocrine emergency but a differential that should be considered in patients presenting critically unwell with systemic illness. We report a case of myxoedema coma in a woman presenting with respiratory failure, hypotension, hypothermia and a reduced level of consciousness, all of which are poor prognostic features in decompensated hypothyroidism. The patient was admitted to critical care for mechanical ventilation and cardiovascular support and treated with a combination of insulin, liothyronine and levothyroxine, making a good recovery. Read More

    Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis.
    Case Rep Endocrinol 2015 5;2015:169194. Epub 2015 Nov 5.
    Endocrinology and Diabetes Department, Prince Charles Hospital, Cwm Taf University Health Board, Merthyr Tydfil CF47 9DT, UK.
    An 82-year-old female with known hypothyroidism was admitted to hospital after being found on the floor. On examination, she was unkempt, confused, bradycardic, hypothermic, and barely arousable. Initial biochemistry revealed a thyroid stimulating hormone (TSH) of >100 mU/L and free thyroxine (FT4) level of 1. Read More

    Myxedema coma with cardiac tamponade and severe cardiomyopathy.
    Proc (Bayl Univ Med Cent) 2015 Oct;28(4):509-11
    Department of Internal Medicine (Majid-Moosa), the Division of Cardiology (Schussler), and the Division of Pulmonary and Critical Care Medicine (Mora), Baylor University Medical Center at Dallas; the Jack and Jane Hamilton Heart and Vascular Hospital (Schussler); and the Texas A&M College of Medicine (Schussler).
    Myxedema coma is an infrequent but potentially fatal complication of hypothyroidism. We present a rare case of previously undiagnosed hypothyroidism presenting in cardiogenic shock from pericardial tamponade and depressed myocardial contractility in myxedema coma. Here, we focus on cardiovascular complications associated with the condition. Read More

    Myxedema Coma with Reversible Cardiopulmonary Failure: a Rare Entity in 21 Century.
    Maedica (Buchar) 2015 Sep;10(3):268-271
    Department of Internal Medicine, Division of Hematology-Oncology, Nebraska Medical Center, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
    Myxedema coma, a rare entity in 21st century in developed nations, is a decompensated phase of hypothyroidism with high mortality rates. We describe a young woman with myxedema, who developed respiratory failure, congestive heart failure and significant pericardial effusion, some of the uncommon manifestations. Decreased cardiac contractility can result in cardiomyopathy and heart failure. Read More

    A Rare Case of Myxedema Coma with Neuroleptic Malignant Syndrome (NMS).
    J Clin Diagn Res 2015 May 1;9(5):VD01-VD03. Epub 2015 May 1.
    DNB Resident, Department of Psychiatry, Base Hospital , Delhi Cantt, India .
    Myxedema coma or hypothyroid crisis is an endocrine emergency and needs ICU management. Neuroleptic malignant syndrome (NMS) is another medical emergency which needs high degree of clinical suspicion else mortality can be high. There is a paradox in co existence of myxedema coma and NMS. Read More

    Complete recovery after severe myxoedema coma complicated by status epilepticus.
    BMJ Case Rep 2015 Mar 25;2015. Epub 2015 Mar 25.
    Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus C, Denmark.
    We report a case of life-threatening myxoedema presenting with hypothermia, hypotension, bradycardia, pericardial effusion and deep coma. The condition was complicated by prolonged status epilepticus. The optimal treatment strategy has been debated over the years and the literature is briefly reviewed. Read More

    Development of an objective tool for the diagnosis of myxedema coma.
    Transl Res 2015 Sep 13;166(3):233-43. Epub 2015 Jan 13.
    Department of Medicine, Indiana University School of Medicine and Methodist Research Institute, Indianapolis, Ind. Electronic address:
    Myxedema coma, a rare entity, with a reported 25%-65% mortality had no objective criteria for making the diagnosis when we began our study. We developed an objective screening tool for myxedema coma to more easily identify patients and examine the best treatment method in future prospective studies to reduce the mortality of this entity. We conducted a retrospective chart review to find all patients aged ≥18 years admitted with myxedema coma from January 1, 2005 through June 13, 2010 at Indiana University Health Methodist Hospital. Read More

    Hashimoto's encephalopathy: report of three cases.
    J Formos Med Assoc 2014 Nov 3;113(11):862-6. Epub 2012 Mar 3.
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:
    Both severe thyrotoxicosis and hypothyroidism may affect brain function and cause a change in consciousness, as seen with a thyroid storm or myxedema coma. However, encephalopathy may also develop in patients with autoimmune thyroid diseases independent of actual thyroid function level, and this is known as Hashimoto's encephalopathy. Although most patients are found to have Hashimoto's thyroiditis, less frequently they have Graves' disease. Read More

    Lithium toxicity and myxedema crisis in an elderly patient.
    Indian J Endocrinol Metab 2013 Dec;17(Suppl 3):S654-6
    Department of Endocrinology, Sheri-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India.
    Unlabelled: While thyroid dysfunction is a frequent complication of lithium treatment, myxedema crisis is a rare occurrence with a handful of cases described. Here, we describe a patient receiving lithium for about a decade for bipolar disorder, who presented with myxedema crisis and lithium toxicity. In this patient, myxedema crisis was likely precipitated by lithium toxicity and community acquired pneumonia. Read More

    Hypothyroidism: causes, killers, and life-saving treatments.
    Emerg Med Clin North Am 2014 May 6;32(2):303-17. Epub 2014 Mar 6.
    Emergency Medicine Residency Program, University of Maryland Medical Center, 110 South Paca Street, 6th Floor Suite 200, Baltimore, MD 21201, USA.
    Hypothyroidism is a very common, yet often overlooked disease. It can have a myriad of signs and symptoms, and is often nonspecific. Identification requires analysis of thyroid hormones circulating in the bloodstream, and treatment is simply replacement with exogenous hormone, usually levothyroxine (Synthroid). Read More

    Amiodarone-induced myxoedema coma.
    BMJ Case Rep 2014 Apr 12;2014. Epub 2014 Apr 12.
    Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
    A 62-year-old man was found to have bradycardia, hypothermia and respiratory failure 3 weeks after initiation of amiodarone therapy for atrial fibrillation. Thyroid-stimulating hormone was found to be 168 μIU/mL (nl. 0. Read More

    Heart failure presenting as myxedema coma: case report and review article.
    Tenn Med 2014 Feb;107(2):39-41
    Department of Cardiovascular Disease, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.
    Hypothyroidism is a common medical problem easily treated when diagnosed but requiring regular follow-up and patient medication compliance. At times, this diagnosis can go untreated resulting in the development of severe consequences such as Myxedema Coma. Of all the clinical symptoms, cardiovascular manifestations tend to be especially severe and often life threatening. Read More

    [Hypothyroidism after radiotherapy of the neck area: monitoring of thyroid function is important].
    Ned Tijdschr Geneeskd 2014 ;158:A6714
    Universitair Medisch Centrum Groningen, Groningen.
    We present three patients with primary hypothyroidism after previous radiotherapy of the neck area. Myxoedema coma occurred in one of these patients. Lifelong follow-up of thyroid function is recommended after radiotherapy of the neck. Read More

    Postoperative myxoedema coma.
    BMJ Case Rep 2014 Feb 13;2014. Epub 2014 Feb 13.
    Department of Medicine, Maharishi Markandeshwar Medical College and Hospital, Solan, Solan, Himachal Pradesh, India.
    Hypothyroidism is a commonly diagnosed endocrine disorder in medicine. Hyponatraemia is reported in up to 10% of hypothyroid patients, although it is usually mild and rarely causes symptoms. Myxoedema coma is a rare manifestation of hypothyroidism and it can be lethal if it goes undiagnosed and untreated. Read More

    A diagnostic scoring system for myxedema coma.
    Endocr Pract 2014 Aug;20(8):808-17
    Division of Endocrinology, Department of Medicine, MedStar Washington Hospital Center, Washington DC.
    Objective: To develop diagnostic criteria for myxedema coma (MC), a decompensated state of extreme hypothyroidism with a high mortality rate if untreated, in order to facilitate its early recognition and treatment.

    Methods: The frequencies of characteristics associated with MC were assessed retrospectively in patients from our institutions in order to derive a semiquantitative diagnostic point scale that was further applied on selected patients whose data were retrieved from the literature. Logistic regression analysis was used to test the predictive power of the score. Read More

    Myxoedema coma: an almost forgotten, yet still existing cause of multiorgan failure.
    BMJ Case Rep 2014 Jan 30;2014. Epub 2014 Jan 30.
    Department of Nephrology, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.
    A 48-year-old man was admitted to department of emergency medicine at a tertiary referral hospital due to dizziness and fatigue. Clinical features on admission were non-pitting oedema, dry skin, very sparse hair, a hoarse voice, hypothermia (rectal temperature 28.7°C), macroglossia, sinus bradycardia and slow cerebration. Read More

    [Myxedema coma in a patient with type 1 neurofibromatosis: rare association].
    Arq Bras Endocrinol Metabol 2013 Dec;57(9):743-7
    Myxedema coma, a rare but fatal emergency, is an extreme expression of hypothyroidism. We describe a 51-year-old male patient who has discontinued hypothyroidism treatment 10 months earlier and developed lethargy, edema, and cold intolerance symptoms. He also had a previous diagnosis of neurofibromatosis. Read More

    Thyroid disease and the nervous system.
    Handb Clin Neurol 2014 ;120:703-35
    Sheffield Institute for Translational Neuroscience, University of Sheffield and Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK. Electronic address:
    Thyroid disorders are common in the general population and in hospitalized patients. Thyroid disease may present first with neurological complications or else may occur concurrently in patients suffering other neurological disorders, particularly those with an autoimmune etiology. For this reason neurologists will commonly encounter patients with thyroid disease. Read More

    Cardiac tamponade as initial presenting feature of primary hypothyroidism in the ED.
    Am J Emerg Med 2014 Jun 26;32(6):683.e1-3. Epub 2013 Nov 26.
    Department of Emergency Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. Electronic address:
    Pericardial effusion is commonly detected in patients with severe hypothyroidism and is typically mild; rarely, it may lead to cardiac tamponade. Cardiac tamponade with myxedema coma as initial presenting feature of previously unrecognized hypothyroidism is rare. This case highlights that previously undiagnosed hypothyroidism can manifest as myxedema coma with shock due to pericardial tamponade particularly in winters because a cold environment can precipitate myxedema. Read More

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