408 results match your criteria Hypothyroidism and Myxedema Coma


Myxoedema coma in a 2-year-old girl with untreated congenital hypothyroidism: Case report and literature review.

J Paediatr Child Health 2018 Dec 12. Epub 2018 Dec 12.

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jpc.14339DOI Listing
December 2018

Postoperative myxedema coma in patients undergoing major surgery: Case series.

Auris Nasus Larynx 2018 Nov 16. Epub 2018 Nov 16.

Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: Myxedema coma is a serious complication of hypothyroidism that can be precipitated by major surgery. It is extremely rare, with only a few reports in the literature. This study aims to present a relatively large case series of post-surgical myxedema coma and to analyze medical and surgical risk factors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anl.2018.10.019DOI Listing
November 2018
14 Reads

Misleading symptoms and successful noninvasive rewarming of a patient with severe hypothermia (23.1 °C).

Anaesthesist 2018 Dec 30;67(12):931-935. Epub 2018 Oct 30.

Department of Anesthesiology, Ludwig Maximilian University Hospital, Marchioninistr. 15, 81377, Munich, Germany.

Accidental severe hypothermia is a medical emergency in which symptoms may include coma, apnea, pulmonary edema, ventricular dysrhythmia or asystole. Despite optimal treatment, mortality remains high. This article reports a case of severe hypothermia in a geriatric hypothyroid patient, where despite a body core temperature of 23. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00101-018-0508-4DOI Listing
December 2018
3 Reads

Comatose patient with hypothermia, dyspnea, and general edema in the emergency department: a case report.

J Int Med Res 2018 Oct 15;46(10):4338-4342. Epub 2018 Aug 15.

1 Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan.

Patients presenting to the emergency department with hypothermia are rare and often require prompt diagnosis and management. Myxedema coma, which may cause severe hypothermia, is a true endocrine emergency requiring early and appropriate treatment. We report on a 47-year-old woman with a history of hyperthyroidism who underwent thyroidectomy 5 years previously, with no regular medication or examinations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0300060518791074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166344PMC
October 2018
12 Reads

Myxedema Coma Following the Administration of Gonadotropin-releasing Hormone Agonist Complicated by Acute Pancreatitis.

Intern Med 2018 Nov 6;57(21):3117-3122. Epub 2018 Jun 6.

Diabetes Center, Ebina General Hospital, Japan.

Gonadotropin-releasing hormone (GnRH) agonists have been used for the treatment of various diseases. Although autoimmune thyroid disease has been reported as a rare complication of these agents, the symptoms are almost always transient and non-life-threatening. We herein report a rare case of an 83-year-old man receiving GnRH agonist treatment for prostate cancer who developed myxedema coma complicated by acute pancreatitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2169/internalmedicine.0639-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262710PMC
November 2018
30 Reads

Effects of Long-Term Combination LT4 and LT3 Therapy for Improving Hypothyroidism and Overall Quality of Life.

South Med J 2018 06;111(6):363-369

From the Departments of Internal Medicine, Research and Biostatistical Analysis, and Endocrinology, UPMC Pinnacle Health, Harrisburg, Pennsylvania.

Objectives: Hypothyroidism results in decreased mood and neurocognition, weight gain, fatigue, and many other undesirable symptoms. The American Association of Clinical Endocrinologists, the American Thyroid Association (ATA), and The Endocrine Society recommend levothyroxine (LT4) monotherapy as the treatment for hypothyroidism; however, after years of monotherapy, some patients continue to experience impaired quality of life. Combination LT4 and synthetic liothyronine (LT3) therapy or the use of desiccated thyroid extract (DTE), has not been suggested for this indication based on short-duration studies with no significant benefits. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14423/SMJ.0000000000000823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965938PMC
June 2018
42 Reads
1.120 Impact Factor

Amiodarone induced myxedema coma: Two case reports and literature review.

Heart Lung 2018 Jul - Aug;47(4):429-431. Epub 2018 May 21.

Department of Cardiology, New York Medical College, St. Joseph Medical Center, 703 Main Street, Paterson, NJ 07503, USA.

Amiodarone is a benzofuran derivative that contains 37% iodine by weight and is structurally similar to the thyroid hormones. Amiodarone has a complex effect on the thyroid gland, ranging from abnormalities of thyroid function tests to overt thyroid dysfunction, with either thyrotoxicosis or hypothyroidism. Myxedema coma secondary to amiodarone use has been rarely reported in the literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrtlng.2018.03.012DOI Listing
May 2018
5 Reads

Myxedema Coma due to Hashimoto Thyroiditis: A Rare but Real Presentation of Failure to Thrive in Infancy.

Horm Res Paediatr 2018 May 4:1-5. Epub 2018 May 4.

Background: Hashimoto thyroiditis (HT) is uncommon in infancy, and myxedema coma (MC) is even less common. While prior reports have documented these entities separately, to our knowledge, MC in combination with HT has not been reported before in this age group.

Methods/results: A 10-month-old female presented with ptosis, lethargy, dysphagia, and failure to thrive (FTT). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000488467DOI Listing
May 2018
26 Reads

[Thyroid Storm and Myxedema Coma].

Dtsch Med Wochenschr 2018 Mar 15;143(6):397-405. Epub 2018 Mar 15.

Thyroid storm and myxedema coma are the most severe clinical forms of thyroid dysfunction. While both hyper- and hypothyroidsm are common diseases, thyroid storm and myxedema coma are rare. Due to their unspecific signs and symptoms they are often difficult to diagnose. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0043-111728DOI Listing
March 2018
7 Reads

Myxedema Coma.

Authors:
Atif Munir

J Ayub Med Coll Abbottabad 2018 Jan-Mar;30(1):119-120

Diabetes and Endocrinology, University Hospital of Hartlepool, UK.

Myxedema may be the first presentation of patients with undiagnosed hypothyroidism. Definitive management is with thyroid hormone but supportive measures, identification and treatment of precipitating factors in an appropriately safe environment are vital. There is no consensus about preferred thyroid hormone regimen. Read More

View Article

Download full-text PDF

Source
August 2018
4 Reads

Dementia, cardiomyopathy and pseudo-obstruction in a 63-year-old female.

Authors:
A Garrahy A Agha

Eur J Intern Med 2018 09 2;55:e5-e6. Epub 2018 Mar 2.

Department of Endocrinology, Beaumont Hospital and RCSI Medical School, Beaumont, Dublin 9, Ireland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejim.2018.02.028DOI Listing
September 2018
3 Reads

Management of concomitant metabolic encephalopathy and meningioma with vasogenic edema and impending herniation.

Surg Neurol Int 2018 8;9:25. Epub 2018 Feb 8.

Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, Illinois, USA.

Background: Altered mental status describes impaired mental functioning ranging from confusion to coma and indicates an illness, either metabolic or structural in nature. Metabolic causes include hypothyroidism, hyperuremia, hypo/hyperglycemia, hypo/hypernatremia, and encephalopathy. The structural causes include tumors, brain hemorrhage, infection, and stroke. Read More

View Article

Download full-text PDF

Source
http://surgicalneurologyint.com/surgicalint-articles/managem
Publisher Site
http://dx.doi.org/10.4103/sni.sni_357_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820833PMC
February 2018
22 Reads

Case of myxedema coma induced by lithium carbonate in a patient with schizophrenia.

Psychiatry Clin Neurosci 2018 02 23;72(2):131. Epub 2017 Dec 23.

Department of Psychiatry, Otaru General Hospital, Hokkaido, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pcn.12626DOI Listing
February 2018
7 Reads

Sudden cardiac arrest as a rare presentation of myxedema coma: case report.

J Community Hosp Intern Med Perspect 2017 18;7(5):318-320. Epub 2017 Oct 18.

Department of Pulmonary Medicine, Interfaith Medical Centre, Brooklyn, NY, USA.

Myxedema coma is a decompensated hypothyroidism which occurs due to long-standing, undiagnosed, or untreated hypothyroidism. Untreated hypothyroidism is known to affect almost all organs including the heart. It is associated with a decrease in cardiac output, stroke volume due to decreased myocardial contractility, and an increase in systemic vascular resistance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/20009666.2017.1374110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676798PMC
October 2017
9 Reads

Myasthenic Crisis Complicated with Myxedema, Positive for Both Anti-acetylcholine Receptor and Anti-muscle-specific Tyrosine Kinase Antibodies.

Intern Med 2018 Jan 1;57(2):265-268. Epub 2017 Nov 1.

Department of Neurology, Obihiro Kosei General Hospital, Japan.

We herein report the case of myasthenic crisis occurring in a 51-year-old man. He had experienced ptosis, increased body weight with edema, and fatigue with dyspnea. He presented at our emergency department with disturbed consciousness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2169/internalmedicine.9291-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820048PMC
January 2018
2 Reads

Split high-dose oral levothyroxine treatment as a successful therapy option in myxedema coma.

Clin Case Rep 2017 10 8;5(10):1706-1711. Epub 2017 Sep 8.

Division of Endocrinology and Metabolism Department of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok 10400 Thailand.

High-dose intravenous thyroxine (T4) is the preferable treatment for myxedema coma. We describe the clinical course of a 69-year-old man who presented with myxedema coma and received oral levothyroxine (LT4) therapy (1 mg) in a split dose. This suggests split high-dose oral LT4 as a therapeutic option in myxedema coma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ccr3.1131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628197PMC
October 2017
7 Reads

Challenges in the Management of a Patient with Myxoedema Coma in Ghana: A Case Report.

Ghana Med J 2017 Mar;51(1):39-42

Neurology Unit, Department of Medicine and Therapeutics, School of Medicine and Dentistry, University of Ghana, PO Box GP 4236, Accra, Ghana.

Myxoedema coma is a rare life-threatening disease, and it is essential that it is managed appropriately to reduce the associated high mortality. However, in the setting where efficient healthcare delivery is hampered by inadequacies, the management of such cases may pose a significant challenge. We present the case of a middle-aged woman diagnosed with myxoedema coma and severe hyponatremia. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611947PMC
March 2017
9 Reads

[Thyroid emergencies : Thyroid storm and myxedema coma].

Internist (Berl) 2017 Oct;58(10):1011-1019

Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Marchioninistraße 15, 81377, München, Deutschland.

Thyroid emergencies are rare life-threatening endocrine conditions resulting from either decompensated thyrotoxicosis (thyroid storm) or severe thyroid hormone deficiency (myxedema coma). Both conditions develop out of a long-standing undiagnosed or untreated hyper- or hypothyroidism, respectively, precipitated by an acute stress-associated event, such as infection, trauma, or surgery. Cardinal features of thyroid storm are myasthenia, cardiovascular symptoms, in particular tachycardia, as well as hyperthermia and central nervous system dysfunction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00108-017-0306-0DOI Listing
October 2017
27 Reads

[Myxedema coma].

Medicina (B Aires) 2017 ;77(4):321-328

Department of Medicine, Washington Hospital Center, Washington, DC, USA.

Hypothyroidism is a frequently diagnosed and simply treated disease. If not recognised, however, in time it may develop into the most severe manifestation of hypothyroidism known as myxedema coma. The term "myxedema coma" is generally seen as misleading since most patients do not initially present in a coma. Read More

View Article

Download full-text PDF

Source
July 2018
37 Reads

Thyroid Emergencies: New Insight into Old Problems.

J Assoc Physicians India 2017 Aug;65(8):68-76

Senior Resident, Dept. of Medicine, LHMC and Associated Hospitals, New Delhi.

Thyroid emergencies are major life-threatening endocrine conditions associated with life-threatening disorders resulting from either severe deficiency or excess of thyroid hormones. Deficiency of thyroid hormones may present as myxedema coma whereas excessive hormone production can present as life threatening thyrotoxic storm. The diagnosis of both requires a high index of clinical suspicion. Read More

View Article

Download full-text PDF

Source
August 2017
14 Reads

Thoracentesis-reverting cardiac tamponade physiology in a patient with myxedema coma and large pleural effusion.

Proc (Bayl Univ Med Cent) 2017 Jul;30(3):295-297

Departments of Internal Medicine (Werlang) and Critical Care Medicine (Pimentel, Diaz-Gomez), Mayo Clinic, Jacksonville, Florida. Dr. Pimentel is currently at Irmandade Santa Casa de Misericordia, Porto Alegre, Brazil.

A large pleural effusion causing cardiac tamponade physiology and severe hemodynamic compromise is an uncommon event. We report a case of a 53-year-old woman with severe hypothyroidism presenting with myxedema coma and refractory shock. Her hemodynamic status failed to respond to fluid resuscitation and vasopressors. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468018PMC
July 2017
6 Reads

Myxedema coma: A case report of pediatric emergency care.

Medicine (Baltimore) 2017 May;96(21):e6952

aPediatric Critical Care Medicine, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine bDepartment of Pediatric Endocrinology/Genetics, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai Institute for Pediatric Research, Shanghai, China.

Raionale: Myxedema coma (MC) is extremely rare but lethal in pediatric patients with hypothyroidism leading to altered mental status and hypothermia. But there is no clinical guideline for such cases.

Patient Concerns: A 6-year-old Chinese girl presented with coma and hypothermia preceded by pneumonia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000006952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457868PMC
May 2017
20 Reads

Diagnosis of myxedema coma complicated by renal failure: a case report.

Clin Case Rep 2017 04 21;5(4):399-402. Epub 2017 Feb 21.

Department of General Medicine Himi Municipal Hospital Kanazawa Medical University 31-9 Saiwai-cho Himi Toyama Japan.

Myxedema coma, caused by severe lack of thyroid hormone, is characterized by deterioration of mental status, hypothermia, hypotension, hyponatremia, and hypoventilation. We describe an 84-year-old woman who presented with renal failure and new onset severe hypothyroidism leading to challenges in the recognition of myxedema coma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ccr3.850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378864PMC
April 2017
9 Reads

Clinical characteristics and outcomes of myxedema coma: Analysis of a national inpatient database in Japan.

J Epidemiol 2017 Mar 5;27(3):117-122. Epub 2017 Jan 5.

Department of General Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.

Background: Myxedema coma is a life-threatening and emergency presentation of hypothyroidism. However, the clinical features and outcomes of this condition have been poorly defined because of its rarity.

Methods: We conducted a retrospective observational study of patients diagnosed with myxedema coma from July 2010 through March 2013 using a national inpatient database in Japan. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.je.2016.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350620PMC
March 2017
8 Reads

Myxedema Psychosis in a Patient With Undiagnosed Hashimoto Thyroiditis.

J Am Osteopath Assoc 2017 Jan;117(1):50-54

Myxedema psychosis is uncommon in patients with primary hypothyroidism. Most often, this disease state can be found in patients with Hashimoto thyroiditis or after total thyroidectomy. Chronic hypothyroidism can lead to an insidious onset of psychiatric symptoms in patients, such as dementia, delirium, psychosis, hallucinations, and coma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7556/jaoa.2017.007DOI Listing
January 2017
9 Reads

An Atypical Case of Myxedema Coma with Concomitant Nonconvulsive Seizure.

Case Rep Crit Care 2016 30;2016:3438080. Epub 2016 Oct 30.

Pulmonary and Critical Care, St. John's Riverside Hospital, 967 N. Broadway, Yonkers, NY 10701, USA.

Hypothyroidism is a prevalent condition in the general population that is treatable with appropriately dosed thyroid hormone replacement medication. Infrequently, patients will present with myxedema coma, characterized by hypothermia, hypotension, bradycardia, and altered mental status in the setting of severe hypothyroidism. Myxedema coma has also been known to manifest in a number of unusual and dangerous forms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/3438080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107213PMC
October 2016
4 Reads

Impending myxedema coma as the initial presentation of lung cancer.

J Formos Med Assoc 2017 06 4;116(6):488-489. Epub 2016 Nov 4.

Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jfma.2016.09.009DOI Listing
June 2017
4 Reads
1.700 Impact Factor

Myxedema Coma Secondary to Central Hypothyroidism: A Rare but Real Cause of Altered Mental Status in Pediatrics.

Horm Res Paediatr 2017 16;87(5):350-353. Epub 2016 Sep 16.

Section of Endocrinology, Metabolism and Diabetes, Nationwide Children's Hospital, Columbus, Ohio, USA.

Background: Myxedema coma (MC), a medical emergency defined as severe hypothyroidism leading to altered mental status, is more common in older women with hypothyroidism.

Methods/results: A 7-year-old Caucasian male with chromosome 1q deletion presented with altered mental status preceded by milestone regression. His presenting labs results were: thyroid-stimulating hormone (TSH) 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000449223DOI Listing
March 2018
11 Reads

Thyroid Emergencies.

Authors:
Angela M Leung

J Infus Nurs 2016 Sep-Oct;39(5):281-6

Division of Endocrinology, David Geffen School of Medicine at UCLA, and the VA Greater Los Angeles Healthcare System, Los Angeles, California. Angela M. Leung, MD, MSc, is an assistant clinical professor of medicine in the Division of Endocrinology at the David Geffen School of Medicine at the University of California, Los Angeles, and the VA Greater Los Angeles Healthcare System, both in Los Angeles, California.

Myxedema coma and thyroid storm are thyroid emergencies associated with increased mortality. Prompt recognition of these states-which represent the severe, life-threatening conditions of extremely reduced or elevated circulating thyroid hormone concentrations, respectively-is necessary to initiate treatment. Management of myxedema coma and thyroid storm requires both medical and supportive therapies and should be treated in an intensive care unit setting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/NAN.0000000000000186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657262PMC
June 2017
13 Reads

Myxoedema coma: a forgotten presentation of extreme hypothyroidism.

BMJ Case Rep 2016 Jun 28;2016. Epub 2016 Jun 28.

The Reading Hospital and Medical Center, West Reading, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2016-216225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932398PMC
June 2016
7 Reads

Pediatric Patient With Altered Mental Status and Hypoxemia: Case Report.

Pediatr Emerg Care 2017 Jul;33(7):486-488

From the *Department of Pediatrics, University of Pittsburgh School of Medicine; †Department of Pediatrics, Children's Hospital of Pittsburgh; ‡Division of Pediatric Endocrinology, Department of Pediatrics, University of Pittsburgh School of Medicine; and §Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Childhood cases of myxedema coma are extremely rare. We report a case of a 5-year-old girl transferred to a tertiary care pediatric emergency department with hypoxemia and altered mental status and diagnosed with severe hypothyroidism and myxedema coma in the setting of acute influenza infection. Although it is rare, myxedema coma must remain in the differential diagnosis for altered mental status and organ dysfunction in the pediatric population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PEC.0000000000000722DOI Listing
July 2017
12 Reads

A rabbit model of fatal hypothyroidism mimicking "myxedema coma" established by microscopic total thyroidectomy.

Endocr J 2016 Jun 26;63(6):523-32. Epub 2016 Mar 26.

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Myxedema coma (MC) is a life-threatening endocrine crisis caused by severe hypothyroidism. However, validated diagnostic criteria and treatment guidelines for MC have not been established owing to its rarity. Therefore, a valid animal model is required to investigate the pathologic and therapeutic aspects of MC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1507/endocrj.EJ16-0005DOI Listing
June 2016
8 Reads

Precision Medicine Comes to Thyroidology.

Authors:
Paul W Ladenson

J Clin Endocrinol Metab 2016 Mar 23;101(3):799-803. Epub 2016 Feb 23.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-0003.

Context: The broad spectrum of thyroid disease severity--from subclinical hypothyroidism to myxedema coma, subclinical thyrotoxicosis to thyroid storm, and microscopic papillary to anaplastic cancers--has always demanded that clinicians individualize their management of thyroid patients. Deepening knowledge of thyroid pathophysiology along with advances in diagnostic, prognostic, and therapeutic technologies applicable to thyroid diseases position this field to ride the wave of precision medicine in the decade ahead. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2015-3695DOI Listing
March 2016
6 Reads

Myxoedema coma in the setting of hyperglycaemic hyperosmolar state.

BMJ Case Rep 2016 Jan 11;2016. Epub 2016 Jan 11.

Anaesthesia and Critical Care, Tameside Hospital NHS Foundation Trust, Lancashire, UK.

Decompensated hypothyroidism is a rare endocrine emergency but a differential that should be considered in patients presenting critically unwell with systemic illness. We report a case of myxoedema coma in a woman presenting with respiratory failure, hypotension, hypothermia and a reduced level of consciousness, all of which are poor prognostic features in decompensated hypothyroidism. The patient was admitted to critical care for mechanical ventilation and cardiovascular support and treated with a combination of insulin, liothyronine and levothyroxine, making a good recovery. Read More

View Article

Download full-text PDF

Source
http://casereports.bmj.com/content/2016/bcr-2015-213411.full
Web Search
http://casereports.bmj.com/lookup/doi/10.1136/bcr-2015-21341
Publisher Site
http://dx.doi.org/10.1136/bcr-2015-213411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716335PMC
January 2016
18 Reads

Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis.

Case Rep Endocrinol 2015 5;2015:169194. Epub 2015 Nov 5.

Endocrinology and Diabetes Department, Prince Charles Hospital, Cwm Taf University Health Board, Merthyr Tydfil CF47 9DT, UK.

An 82-year-old female with known hypothyroidism was admitted to hospital after being found on the floor. On examination, she was unkempt, confused, bradycardic, hypothermic, and barely arousable. Initial biochemistry revealed a thyroid stimulating hormone (TSH) of >100 mU/L and free thyroxine (FT4) level of 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2015/169194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651700PMC
November 2015
17 Reads

Myxedema coma with cardiac tamponade and severe cardiomyopathy.

Proc (Bayl Univ Med Cent) 2015 Oct;28(4):509-11

Department of Internal Medicine (Majid-Moosa), the Division of Cardiology (Schussler), and the Division of Pulmonary and Critical Care Medicine (Mora), Baylor University Medical Center at Dallas; the Jack and Jane Hamilton Heart and Vascular Hospital (Schussler); and the Texas A&M College of Medicine (Schussler).

Myxedema coma is an infrequent but potentially fatal complication of hypothyroidism. We present a rare case of previously undiagnosed hypothyroidism presenting in cardiogenic shock from pericardial tamponade and depressed myocardial contractility in myxedema coma. Here, we focus on cardiovascular complications associated with the condition. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569241PMC
October 2015
7 Reads

Myxedema Coma with Reversible Cardiopulmonary Failure: a Rare Entity in 21 Century.

Maedica (Buchar) 2015 Sep;10(3):268-271

Department of Internal Medicine, Division of Hematology-Oncology, Nebraska Medical Center, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.

Myxedema coma, a rare entity in 21st century in developed nations, is a decompensated phase of hypothyroidism with high mortality rates. We describe a young woman with myxedema, who developed respiratory failure, congestive heart failure and significant pericardial effusion, some of the uncommon manifestations. Decreased cardiac contractility can result in cardiomyopathy and heart failure. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327827PMC
September 2015
17 Reads

[Descent into hypothyroid coma].

Authors:
H S Füeßl

MMW Fortschr Med 2015 Aug;157(14):36

, .

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s15006-015-3413-7
Publisher Site
http://dx.doi.org/10.1007/s15006-015-3413-7DOI Listing
August 2015
7 Reads

A Rare Case of Myxedema Coma with Neuroleptic Malignant Syndrome (NMS).

J Clin Diagn Res 2015 May 1;9(5):VD01-VD03. Epub 2015 May 1.

DNB Resident, Department of Psychiatry, Base Hospital , Delhi Cantt, India .

Myxedema coma or hypothyroid crisis is an endocrine emergency and needs ICU management. Neuroleptic malignant syndrome (NMS) is another medical emergency which needs high degree of clinical suspicion else mortality can be high. There is a paradox in co existence of myxedema coma and NMS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7860/JCDR/2015/13008.5868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484133PMC
May 2015
7 Reads

[Patient with Parkinson's disease und unclear somnolence].

Authors:
Thomas Kuhl

Dtsch Med Wochenschr 2015 Apr 29;140(9):643, 689. Epub 2015 Apr 29.

Praxis für Kardiologie Dormagen.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0041-101568DOI Listing
April 2015
5 Reads

Complete recovery after severe myxoedema coma complicated by status epilepticus.

BMJ Case Rep 2015 Mar 25;2015. Epub 2015 Mar 25.

Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus C, Denmark.

We report a case of life-threatening myxoedema presenting with hypothermia, hypotension, bradycardia, pericardial effusion and deep coma. The condition was complicated by prolonged status epilepticus. The optimal treatment strategy has been debated over the years and the literature is briefly reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2014-209071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386296PMC
March 2015
11 Reads

Development of an objective tool for the diagnosis of myxedema coma.

Transl Res 2015 Sep 13;166(3):233-43. Epub 2015 Jan 13.

Department of Medicine, Indiana University School of Medicine and Methodist Research Institute, Indianapolis, Ind. Electronic address:

Myxedema coma, a rare entity, with a reported 25%-65% mortality had no objective criteria for making the diagnosis when we began our study. We developed an objective screening tool for myxedema coma to more easily identify patients and examine the best treatment method in future prospective studies to reduce the mortality of this entity. We conducted a retrospective chart review to find all patients aged ≥18 years admitted with myxedema coma from January 1, 2005 through June 13, 2010 at Indiana University Health Methodist Hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.trsl.2015.01.003DOI Listing
September 2015
7 Reads

Hashimoto's encephalopathy: report of three cases.

J Formos Med Assoc 2014 Nov 3;113(11):862-6. Epub 2012 Mar 3.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

Both severe thyrotoxicosis and hypothyroidism may affect brain function and cause a change in consciousness, as seen with a thyroid storm or myxedema coma. However, encephalopathy may also develop in patients with autoimmune thyroid diseases independent of actual thyroid function level, and this is known as Hashimoto's encephalopathy. Although most patients are found to have Hashimoto's thyroiditis, less frequently they have Graves' disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jfma.2011.05.012DOI Listing
November 2014
24 Reads

Lithium toxicity and myxedema crisis in an elderly patient.

Indian J Endocrinol Metab 2013 Dec;17(Suppl 3):S654-6

Department of Endocrinology, Sheri-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India.

Unlabelled: While thyroid dysfunction is a frequent complication of lithium treatment, myxedema crisis is a rare occurrence with a handful of cases described. Here, we describe a patient receiving lithium for about a decade for bipolar disorder, who presented with myxedema crisis and lithium toxicity. In this patient, myxedema crisis was likely precipitated by lithium toxicity and community acquired pneumonia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/2230-8210.123558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046609PMC
December 2013
7 Reads

Hypothyroidism: causes, killers, and life-saving treatments.

Emerg Med Clin North Am 2014 May 6;32(2):303-17. Epub 2014 Mar 6.

Emergency Medicine Residency Program, University of Maryland Medical Center, 110 South Paca Street, 6th Floor Suite 200, Baltimore, MD 21201, USA.

Hypothyroidism is a very common, yet often overlooked disease. It can have a myriad of signs and symptoms, and is often nonspecific. Identification requires analysis of thyroid hormones circulating in the bloodstream, and treatment is simply replacement with exogenous hormone, usually levothyroxine (Synthroid). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.emc.2013.12.003DOI Listing
May 2014
4 Reads

Amiodarone-induced myxoedema coma.

BMJ Case Rep 2014 Apr 12;2014. Epub 2014 Apr 12.

Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA.

A 62-year-old man was found to have bradycardia, hypothermia and respiratory failure 3 weeks after initiation of amiodarone therapy for atrial fibrillation. Thyroid-stimulating hormone was found to be 168 μIU/mL (nl. 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2013-202338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987248PMC
April 2014
9 Reads

Heart failure presenting as myxedema coma: case report and review article.

Tenn Med 2014 Feb;107(2):39-41

Department of Cardiovascular Disease, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.

Hypothyroidism is a common medical problem easily treated when diagnosed but requiring regular follow-up and patient medication compliance. At times, this diagnosis can go untreated resulting in the development of severe consequences such as Myxedema Coma. Of all the clinical symptoms, cardiovascular manifestations tend to be especially severe and often life threatening. Read More

View Article

Download full-text PDF

Source
February 2014
7 Reads

Acute colonic pseudo-obstruction (Ogilvie's syndrome) with myxedema coma and palmoplantar keratoderma.

Turk J Gastroenterol 2013 ;24(5):455-6

Adnan Menderes University Medical Faculty, Division of Hematology, Aydin, Turkey.

View Article

Download full-text PDF

Source
November 2014
6 Reads