Search our Database of Scientific Publications and Authors

I’m looking for a

    14123 results match your criteria Hypocalcemia

    1 OF 283

    Endocrine Complications of Surgical Treatment of Thyroid Cancer: An Update.
    Exp Clin Endocrinol Diabetes 2017 Apr 25. Epub 2017 Apr 25.
    Department of Endocrinology. Hospital Ramón y Cajal, Madrid (Spain).
    Postoperative hypoparathyroidism (HypoPT) and hypothyroidism (HypoT) are the main endocrine complications after the surgical treatment for thyroid cancer. Postsurgical HypoPT can be transient, protracted or permanent. Its frequency varies according to the underlying cervical pathology, surgical technique, and mainly the experience of the surgeon. Read More

    A rare variant in the FHL1 gene associated with X-linked recessive hypoparathyroidism.
    Hum Genet 2017 Apr 25. Epub 2017 Apr 25.
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
    Isolated familial hypoparathyroidism is an extremely rare disorder, which to date has been linked to several loci including mutations in CASR, GCM2, and PTH, as well as a rare condition defined as X-linked recessive hypoparathyroidism, previously associated with a 1.5 Mb region on Xq26-q27. Here, we report a patient with hypocalcemia-induced seizures leading to the diagnosis of primary hypoparathyroidism. Read More

    Risk factors for postoperative hypocalcemia.
    Updates Surg 2017 Apr 25. Epub 2017 Apr 25.
    Department of General Surgery, General and Obesity Surgical Unit, Second University of Naples, Naples, Italy.
    Hypocalcaemia is one of the most common complications after thyroidectomy; however, it is still unclear what preoperative factors could predict this event. The aim of this study was to evaluate the role of risk factors for hypocalcaemia after total thyroidectomy (TT). Consecutive patients who underwent total thyroidectomyat our institution between January 2014 and January 2016 were enrolled. Read More

    The High Calcium, High Phosphorus Rescue Diet Is Not Suitable to Prevent Secondary Hyperparathyroidism in Vitamin D Receptor Deficient Mice.
    Front Physiol 2017 10;8:212. Epub 2017 Apr 10.
    Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-WittenbergHalle, Germany.
    The vitamin D receptor (VDR) knockout (KO) mouse is a common model to unravel novel metabolic functions of vitamin D. It is recommended to feed these mice a high calcium (2%), high phosphorus (1.25%) diet, termed rescue diet (RD) to prevent hypocalcaemia and secondary hyperparathyroidism. Read More

    A link between central kynurenine metabolism and bone strength in rats with chronic kidney disease.
    PeerJ 2017 20;5:e3199. Epub 2017 Apr 20.
    Department of Pharmacodynamics, Medical University of Bialystok, Bialystok, Poland.
    Background: Disturbances in mineral and bone metabolism represent one of the most complex complications of chronic kidney disease (CKD). Serotonin, a monoamine synthesized from tryptophan, may play a potential role in bone metabolism. Brain-derived serotonin exerts a positive effect on the bone structure by limiting bone resorption and enhancing bone formation. Read More

    Ambulatory thyroidectomy: an anesthesiologist's perspective.
    Local Reg Anesth 2017 5;10:31-39. Epub 2017 Apr 5.
    Department of Anaesthesia and Critical Care.
    Thyroidectomy has been performed on an inpatient basis because of concerns regarding postoperative complications. These include cervical hematoma, bilateral recurrent laryngeal nerve injury and symptomatic hypocalcemia. We have reviewed the current available evidence and aimed to collate published data to generate incidence of the important complications. Read More

    Endocrine and metabolic changes in transition dairy cows are affected by prepartum infusions of a serotonin precursor.
    J Dairy Sci 2017 Apr 20. Epub 2017 Apr 20.
    Veterinary Physiology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland. Electronic address:
    Serotonin (5-HT) has been shown to be involved in calcium homeostasis, modulating calcium concentration in blood. In addition, 5-HT participates in a variety of metabolic pathways, mainly through the modulation of glucose and lipid metabolism. The hypothesis of the present study was that the prepartum administration of 5-hydroxy-l-tryptophan (5-HTP), a 5-HT precursor, would affect endocrine systems related to calcium homeostasis, and interact with other endocrine and metabolic pathways during the transition period. Read More

    Effects of prepartum dietary cation-anion difference on aspects of peripartum mineral and energy metabolism and performance of multiparous Holstein cows.
    J Dairy Sci 2017 Apr 20. Epub 2017 Apr 20.
    Department of Animal Science, Ithaca, NY 14853. Electronic address:
    The objectives of this study were to determine the effect of decreasing dietary cation-anion difference [DCAD; (Na(+) + K(+)) - (Cl(-) + S(2-))] of the prepartum diet on aspects of mineral metabolism, energy metabolism, and performance of peripartum dairy cows. Multiparous Holstein cows (n = 89) were enrolled between 38 and 31 d before expected parturition and randomized to treatments in a completely randomized design (restricted to balance for previous 305-d mature equivalent milk production, parity, and body condition score) at 24 d before expected parturition. Treatments consisted of a low-K ration without anion supplementation [CON; n = 30, DCAD = +18. Read More

    Persistent and recurrent hyperparathyroidism.
    Updates Surg 2017 Apr 22. Epub 2017 Apr 22.
    Department of Endocrine Surgery, La Conception Hospital, Assistance Publique Hopitaux de Marseille, 147 BD Baille, 13005, Marseille, France.
    Despite remarkable progress in imaging modalities and surgical management, persistence or recurrence of primary hyperparathyroidism (PHPT) still occurs in 2.5-5% of cases of PHPT. The aim of this review is to expose the management of persistent and recurrent hyperparathyroidism. Read More

    Resolution of Primary Immune Defect in 22q11.2 Deletion Syndrome.
    J Clin Immunol 2017 Apr 20. Epub 2017 Apr 20.
    Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
    Purpose: Patients with 22q11.2 deletion syndrome have a variable decrease in immunological parameters, especially regarding T cell counts. The aim of this study was to investigate immunological change over time and factors associated with immunological recovery among patients with 22q11. Read More

    Can Parathormon Levels after Ipsilateral Lobectomy Predict Postoperative Hypocalcemia in Patients Undergoing Total Thyroidectomy?
    Am Surg 2017 Apr;83(4):421-427
    The purpose of this study was to investigate the relationship between the serum parathormone (PTH) levels measured after completion of hemithyroidectomy on the first side during total thyroidectomy and the postoperative hypocalcemia. The patients were divided into two groups, as those who demonstrated a decrease in PTH levels measured after completion of hemithyroidectomy of the first side (Group 1, n = 43) and those who did not demonstrate a decrease in PTH levels (Group 2, n = 24). The serum PTH levels were measured just before the incision (PTHi), when the hemithyroidectomy stage had been completed (PTHht), at the end of the operation (PTHtt), and at the postoperative 24th hour (PTH24hr). Read More

    Six-Year Experience of Outpatient Total and Completion Thyroidectomy at a Single Academic Institution.
    Am Surg 2017 Apr;83(4):381-384
    Outpatient thyroidectomy has become slowly accepted with various published reports predominantly examining partial or subtotal thyroidectomy. Concerns regarding the safety of outpatient total and completion thyroidectomy remain, especially with regard to vocal fold paralysis, hypocalcemia, and catastrophic hematoma. We aimed to evaluate the safety of outpatient thyroid surgery in a large cohort by retrospectively comparing outcomes in those who underwent outpatient (n = 251) versus inpatient (n = 291) completion or total thyroidectomy between February 2009 and February 2015. Read More

    Idiopathic hypoparathyroidism with extensive intracranial calcification in children: First report from Saudi Arabia.
    Medicine (Baltimore) 2017 Apr;96(16):e6347
    aPediatric Hepatologist, Faculty of Medicine, Cairo University, Cairo, Egypt. Pediatric Hepatologist, Alhada Armed Forces Hospital, Taif, KSA bPediatric endocrinologist, Armed Forces Hospitals of Taif Region, Taif, KSA cPediatric neonatologist, Alhada Armed Forces Hospital, Taif, KSA dPediatric endocrinologist, Alhada Armed Forces Hospital, Taif, KSA ePediatrics, Children Hospital, Taif, KSA fPediatric Allergist and immunologist Alhada Armed Forces Hospital, Taif, KSA gPediatric Nephrologist, College of Medicine, Taif University, Taif, KSA hMedical intern, Taif University, Taif, KSA iPediatric Hematologist and Oncologist, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
    Rationale: Pediatric idiopathic hypoparathyroidism with extensive intracranial calcifications outside the basal ganglia (BG) is extremely rare with less than 10 cases worldwide.

    Patient Concerns: An 11-year-old Saudi male child presented with tetany with otherwise normal neurological and other body system examination diagnoses severe hypocalcemia for differential diagnosis.

    Interventions: Further investigations revealed hyperphosphatemia and undetectable serum intact parathyroid hormone. Read More

    Association of Preoperative Calcium and Calcitriol Therapy With Postoperative Hypocalcemia After Total Thyroidectomy.
    JAMA Otolaryngol Head Neck Surg 2017 Apr 13. Epub 2017 Apr 13.
    Department of Otolaryngology-Head and Neck Surgery, University of Virginia Health System, Charlottesville.
    Importance: Hypocalcemia is the most common complication after total thyroidectomy and can result in prolonged hospital admissions and increased hospital charges.

    Objective: To determine the effectiveness of preoperative calcium and calcitriol supplementation in reducing hypocalcemia following total thyroidectomy.

    Design, Setting, And Participants: A retrospective cohort study was conducted at a tertiary care center in 65 patients undergoing total thyroidectomy by a single surgeon. Read More

    Can denosumab be a substitute, competitor, or complement to bisphosphonates?
    Korean J Pain 2017 Apr 31;30(2):86-92. Epub 2017 Mar 31.
    Department of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, Yangsan, Korea.
    Osteoblasts, originating from mesenchymal cells, make the receptor activator of the nuclear factor kappa B ligand (RANKL) and osteoprotegerin (OPG) in order to control differentiation of activated osteoclasts, originating from hematopoietic stem cells. When the RANKL binds to the RANK of the pre-osteoclasts or mature osteoclasts, bone resorption increases. On the contrary, when OPG binds to the RANK, bone resorption decreases. Read More

    Association between subclinical hypocalcemia in the first 3 days of lactation and reproductive performance of dairy cows.
    Theriogenology 2017 May 25;94:1-7. Epub 2017 Jan 25.
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA. Electronic address:
    The objective of this study was to determine the effects of subclinical hypocalcemia on reproductive performance in dairy cows. In a prospective cohort study, 97 cows on 2 dairy farms with automatic milking systems were monitored for subclinical hypocalcemia. Animals were enrolled 7 ± 3 days prior to estimated calving date and three parity groups were defined based on the lactation that the animals were going to start: lactation = 1, lactation = 2, and lactation ≥3. Read More

    A noninferiority trial comparing a heparin-grafted membrane plus citrate-containing dialysate versus regional citrate anticoagulation: results of the CiTED study.
    Nephrol Dial Transplant 2017 Apr;32(4):707-714
    Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
    Background.: Anticoagulation is a prerequisite for successful haemodialysis. Heparin and low-molecular weight heparins are routinely used despite increased bleeding risk. Read More

    Transoral endoscopic thyroidectomy: preliminary experience in Italy.
    Updates Surg 2017 Apr 12. Epub 2017 Apr 12.
    Minimally Invasive and Endocrine Surgery Division, Department of Surgery Police General Hospital, Bangkok, Thailand.
    Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a feasible novel surgical procedure that does not need visible incisions. We describe our initial experience with TOETVA. We recruited 15 patients who were willing to undergo TOETVA. Read More

    Single-Incision, Gasless, Endoscopic Trans-Axillary Total Thyroidectomy: A Feasible and Oncologic Safe Surgery in Patients with Papillary Thyroid Carcinoma.
    J Laparoendosc Adv Surg Tech A 2017 Apr 12. Epub 2017 Apr 12.
    1 Department of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
    Background: The aim of this study is to compare the feasibility and oncologic safety of Single-incision, gasless, Endoscopic trans-axillary bilateral Total thyroidectomy (SET) with open cervical total thyroidectomy in patients with papillary thyroid carcinoma (PTC).

    Materials And Methods: From March 2008 to December 2012, PTC patients underwent bilateral total thyroidectomy. Conventional, open surgery was performed on 538 patients (Group O) and endoscopic surgery was performed on 200 patients (Group E). Read More

    Cholecalciferol 20 000 IU Once Weekly in HIV-Positive Patients with Low Vitamin D Levels: Result from a Cohort Study.
    J Int Assoc Provid AIDS Care 2017 Jan 1:2325957417702487. Epub 2017 Jan 1.
    5 MUC Research, Munich, Germany.
    Purpose: To evaluate efficacy and safety of 20 000 IU cholecalciferol weekly in HIV-infected patients.

    Methods: Longitudinal data for 243 HIV-infected patients with paired 25-OH-vitamin D3 values for the same month in 2 consecutive years were stratified by the initiation of supplementation in this retrospective study.

    Results: After 1 year of administration of cholecalciferol 20 000 IU weekly, about 78% of patients with initial vitamin D level <20 µg/L achieved vitamin D levels >20 µg/L and 42% achieved levels >30 µg/L. Read More

    Basal Ganglia Calcification with Tetanic Seizure Suggest Mitochondrial Disorder.
    Am J Case Rep 2017 Apr 9;18:375-380. Epub 2017 Apr 9.
    Department of Radiology, Krankenanstalt Rudolfstiftung, Vienna, Austria.
    BACKGROUND Basal ganglia calcification (BGC) is a rare sporadic or hereditary central nervous system (CNS) abnormality, characterized by symmetric or asymmetric calcification of the basal ganglia. CASE REPORT We report the case of a 65-year-old Gypsy female who was admitted for a tetanic seizure, and who had a history of polyneuropathy, restless-leg syndrome, retinopathy, diabetes, hyperlipidemia, osteoporosis with consecutive hyperkyphosis, cervicalgia, lumbalgia, struma nodosa requiring thyroidectomy and consecutive hypothyroidism, adipositas, resection of a vocal chord polyp, arterial hypertension, coronary heart disease, atheromatosis of the aorta, peripheral artery disease, chronic obstructive pulmonary disease, steatosis hepatis, mild renal insufficiency, long-term hypocalcemia, hyperphosphatemia, impingement syndrome, spondylarthrosis of the lumbar spine, and hysterectomy. History and clinical presentation suggested a mitochondrial defect which also manifested as hypoparathyroidism or Fanconi syndrome resulting in BGC. Read More

    What is the care pathway of patients who undergo thyroid surgery in France and its potential pitfalls? A national cohort.
    BMJ Open 2017 Apr 7;7(4):e013589. Epub 2017 Apr 7.
    Caisse Nationale d'Assurance Maladie des Travailleurs Salariés, Paris, France.
    Context: The rate of thyroid cancer is increasing in France, as well as concerns about overdiagnosis and treatment.

    Objectives: To examine the care pathway of patients who undergo thyroid surgery in France and detect potential pitfalls.

    Design: A large observational study based on medical reimbursements, 2009-2011. Read More

    Management of childhood thyroid nodules: Surgical and endocrinological experience in more than one hundred cases.
    J Clin Res Pediatr Endocrinol 2017 Apr 7. Epub 2017 Apr 7.
    Objective: The management of childhood thyroid nodules is still a big challenge for clinicians. In this study, we aimed to present our surgical and endocrinological experience in more than one hundred cases as a large experience in children.

    Methods: Retrospective analysis of patients admitted with a thyroid nodule between 2006-2014 was performed. Read More

    Retrospective Study Looking at Cinacalcet in the Management of Hyperparathyroidism after Kidney Transplantation.
    J Transplant 2017 13;2017:8720283. Epub 2017 Mar 13.
    Division of Nephrology, Maisonneuve-Rosemont Hospital and the Department of Medicine, University of Montreal, Montreal, QC, Canada.
    Objectives. The primary objective of this study is to evaluate the use of cinacalcet in the management of hyperparathyroidism in kidney transplant recipients. The secondary objective is to identify baseline factors that predict cinacalcet use after transplantation. Read More

    Delayed Post-Surgical Hypoparathyroidism: The Forgotten Chameleon!
    J Clin Diagn Res 2017 Feb 1;11(2):OD07-OD09. Epub 2017 Feb 1.
    Senior Specialist and Head of Department, Department of Medicine, Tata Main Hospital , Jamshedpur, Jharkhand, India .
    Delayed hypoparathyroidism, due to accidental gland removal or ischemia of parathyroids can present many years after thyroidectomy and symptoms may be non-specific. This condition, if not diagnosed timely, may prove fatal and have serious consequences. Hence, clinicians must have a high index of suspicion to treat this condition. Read More

    Iatrogenic Calcinosis Cutis Successfully Treated with Topical Sodium Thiosulfate.
    Pediatr Dermatol 2017 Apr 6. Epub 2017 Apr 6.
    Department of Pediatrics, Hospital Universitario Virgen del Rocío, Seville, Spain.
    Calcinosis cutis is a term used to describe a group of disorders in which calcium salt deposits form in the skin and subcutaneous tissue. We report a 6-year-old boy with hypoparathyroidism after thyroidectomy who was admitted to the hospital for severe hypocalcemia being treated with calcium gluconate intravenous infusion through peripheral veins. Within a few days we made a diagnosis of iatrogenic calcinosis cutis and treatment with 10% topical sodium thiosulfate was prescribed; complete resolution of lesions was achieved after 6 months, with no local or systemic adverse effects. Read More

    Thyroid Cysts in Cats: A Retrospective Study of 40 Cases.
    J Vet Intern Med 2017 Apr 6. Epub 2017 Apr 6.
    Department of Clinical Science, College of Veterinary Medicine, Cornell University, Ithaca, NY.
    Background: Thyroid cysts are rare in cats and poorly documented.

    Objectives: To report distinguishing clinical features and treatment responses of cats with thyroid cysts.

    Animals: Forty client-owned cats. Read More

    Use and safety of denosumab in cancer patients.
    Int J Clin Pharm 2017 Apr 5. Epub 2017 Apr 5.
    Pharmacy Department, Hospital Clinic de Barcelona, Villarroel 170, 08036, Barcelona, Spain.
    Background Few data have been reported on the use and safety of denosumab in patients with solid tumors and bone metastasis in clinical practice. Objectives To describe the use of denosumab and to analyze its adverse effects (AE) in tertiary hospital cancer outpatients. Methods Retrospective study of patients who started denosumab between January 2013 and June 2015. Read More

    An Adult Case of Chromosome 22q11.2 Deletion Syndrome Associated with a High-positioned Right Aortic Arch.
    Intern Med 2017 1;56(7):865-872. Epub 2017 Apr 1.
    Department of Internal Medicine, Keiaido Hospital, Japan.
    Chromosome 22q11.2 deletion syndrome (22q11.2 DS) has a very wide phenotypic spectrum that includes dysmorphic features, cardiac anomalies, and hypocalcemia arising from hypoparathyroidism. Read More

    Managing hypocalcemia in massive blood transfusion.
    Nursing 2017 May;47(5):26-32
    In New York City, Fidelindo Lim is a clinical assistant professor at New York University College of Nursing, Leon L. Chen is a nurse practitioner in the department of anesthesia and critical care at Memorial Sloan Kettering Cancer Center, and Daniel Borski is a clinical nurse at New York Presbyterian Weill Cornell Hospital.

    Serum 25-Hydroxyvitamin D Insufficiency in Search of a Bone Disease.
    J Clin Endocrinol Metab 2017 Mar 30. Epub 2017 Mar 30.
    Department of Endocrinology, Austin Health, University of Melbourne.
    Introduction: Vitamin D 'insufficiency' and 'deficiency' are defined as a serum 25-hydroxyvitamin D (25(OH)D) below 75 and 30 nmol/L respectively. We aimed to determine whether these values signal hypocalcaemia and hypophosphatemia, secondary hyperparathyroidism, high bone remodeling, low areal bone mineral density (aBMD), microstructural deterioration, or reduced matric mineralization density (MMD), and so suggest whether bone fragility is present.

    Method: Concentrations of 25(OH)D, calcium, phosphate, creatinine and parathyroid hormone (PTH) were measured in 11,855 subjects. Read More

    Secondary Hyperparthyroidism: Pathogenesis, Diagnosis, Preventive and Therapeutic Strategies.
    Rev Endocr Metab Disord 2017 Mar;18(1):79-95
    Laboratory of Nephrology, IIS Fundación Jiménez Díaz, REDinREN, Madrid, Spain.
    Uremic secondary hyperparathyroidism is a multifactorial and complex disease often present in advanced stages of chronic kidney disease. The accumulation of phosphate, the increased FGF23 levels, the reduction in active vitamin D production, and the tendency to hypocalcemia are persistent stimuli for the development and progression of parathyroid hyperplasia with increased secretion of PTH. Parathyroid proliferation may become nodular mainly in cases of advanced hyperparathyroidism. Read More

    Hungry bone syndrome.
    Curr Opin Nephrol Hypertens 2017 Apr 1. Epub 2017 Apr 1.
    aDivision of Nephrology, University of Arkansas for Medical Sciences bCentral Arkansas Veterans Affairs Healthcare System, Little Rock, Arkansas cOffice of Education, Central Alabama Veterans Healthcare System, Montgomery, Alabama, USA.
    Purpose Of Review: In the United States, the number of parathyroidectomies among patients with chronic dialysis has remained stable in the last decade. A fall in serum calcium concentration is common postparathyroidectomy in patients with hyperparathyroidism, which usually resolves in 2-4 days. A severe drop in serum total calcium concentration less than 2. Read More

    Is prophylactic central neck dissection necessary for cN0 differentiated thyroid cancer patients at initial treatment? A meta-analysis of the literature.
    Acta Otorhinolaryngol Ital 2017 Feb;37(1):1-8
    Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Dadong District, Shenyang, Liaoning Province, People's Republic of China.
    Central lymph node metastases are common in patients with differentiated thyroid cancer (DTC). The management of preoperatively nodenegative (cN0) DTC is still under debate. The aim of this study was to analyse the difference in recurrence and surgical complications between thyroidectomy (TT) alone and TT combined with prophylactic central neck dissection (pCND) as initial treatments to DTC patients with cN0 and evaluate the clinic significance of pCND for these patients. Read More

    Safety and Efficacy of Treatment with Asfotase Alfa in Patients with Hypophosphatasia: Results from a Japanese Clinical Trial.
    Clin Endocrinol (Oxf) 2017 Apr 4. Epub 2017 Apr 4.
    Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.
    Objective: Hypophosphatasia (HPP) is a rare skeletal disease characterized by hypomineralization and low alkaline phosphatase activity. Asfotase alfa (AA) has been recently developed to treat HPP complications. This study evaluated its safety and efficacy in Japan. Read More

    Rachitic hypocalcemic cardiomyopathy in an infant.
    J Saudi Heart Assoc 2017 Apr 11;29(2):143-147. Epub 2016 Jun 11.
    Department of Pediatric Cardiology, Medinah Maternity and Children's Hospital, Ministry of Health, Medina, Saudi Arabia.
    Cardiomyopathy in infants is characterized by heart failure in apparently normal children without previous organic cardiac lesions. Cardiomyopathy has been found to comprise four types. Rickets is common in Saudi Arabia, that is why I reviewed this subject. Read More

    Hyperlactatemia Predicts Citrate Intolerance With Regional Citrate Anticoagulation During Continuous Renal Replacement Therapy.
    J Intensive Care Med 2017 Jan 1:885066617701068. Epub 2017 Jan 1.
    1 Division of Nephrology, University Medicine Cluster, National University Hospital, Republic of Singapore.
    Purpose: We aim to determine whether hyperlactatemia, which suggests multi-organ dysfunction and impaired organic substrate metabolism, may predict intolerance to regional citrate anticoagulation (RCA) during continuous venovenous hemofiltration (CVVH).

    Methods: We performed a single-center, retrospective observational study in critically ill patients with acute kidney injury or end-stage renal disease and evaluated the association of peak serum lactate levels with citrate intolerance (CI) during the initial 72 hours of RCA-CVVH, defined by serum total-to-ionized calcium >2.5 plus systemic hypocalcemia. Read More

    Preoperative vitamin D level as predictor of post-thyroidectomy hypocalcemia in patients sustaining transient parathyroid injury.
    Head Neck 2017 Mar 29. Epub 2017 Mar 29.
    Department of Otolaryngology - Head and Neck Surgery, Division of Head and Neck Oncologic and Microvascular Surgery, University of Virginia Health System, Charlottesville, Virginia.
    Background: Several studies have sought to identify predictors of postoperative hypocalcemia after total thyroidectomy; however, there have been conflicting results regarding the impact of preoperative vitamin D deficiency.

    Methods: The medical records of patients undergoing total thyroidectomy were retrospectively reviewed. The number of parathyroid glands identified or reimplanted at the time of surgery was used as a marker of transient parathyroid gland damage. Read More

    Therapeutic efficacy of nutritional support by percutaneous endoscopic gastrostomy in critically ill patients: A self-control clinical trial.
    Pak J Med Sci 2017 Jan-Feb;33(1):75-80
    Yi-Qun Hu Departments of Gastroenterology, Zhongshan Hospital Affiliated to Xiamen University, Xiamen 361004, Fujian, China.
    Background & Objective: Percutaneous endoscopic gastrostomy (PEG) is a procedure to provide enteral nutrition for critically ill patients. It is commonly used in clinical practice; however, the widespread use of PEG is controversial. Our objective was to evaluate the therapeutic effect of nutritional support by PEG in these critically ill patients. Read More

    A safe and effective multi-day colonoscopy bowel preparation for individuals with spinal cord injuries.
    J Spinal Cord Med 2017 Apr 1:1-8. Epub 2017 Apr 1.
    a Spinal Cord Injury Service , Veterans Affairs Puget Sound Health Care System , Seattle , WA , USA.
    Context/objective: Colonoscopy with polypectomy is associated with a reduced risk of colorectal cancer (CRC), but poor bowel cleansing limits the diagnostic yield of the procedure. Patients with spinal cord injury (SCI) frequently have suboptimal bowel cleansing with standard pre-colonoscopy bowel preparation regimens. We aimed to assess the safety, tolerability, and efficacy of a multi-day inpatient bowel preparation regimen in a population of patients with SCI. Read More

    Increased identification of parathyroid glands using near infrared light during thyroid and parathyroid surgery.
    Surg Endosc 2017 Mar 31. Epub 2017 Mar 31.
    Department of General Surgery and The Bariatric and Metabolic Institute, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL, 33331, USA.
    Background: Parathyroid gland (PG) identification during thyroid and parathyroid surgery is challenging. Accidental parathyroidectomy increases the rate of postoperative hypocalcaemia. Recently, autofluorescence with near infrared light (NIRL) has been described for PG visualization. Read More

    Acute symptomatic hypocalcemia from immune checkpoint therapy-induced hypoparathyroidism.
    Am J Emerg Med 2017 Feb 27. Epub 2017 Feb 27.
    Department of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:
    Background: Ipilimumab (a monoclonal antibody against CTLA-4) and nivolumab (a humanized antibody against PD-1) target these immune checkpoint pathways and are used for treatment of melanoma and an increasing number of other cancers. However, they may cause immune-related adverse effects (IRAEs). Although many endocrinopathies are known to be IRAEs, primary hypoparathyroidism with severe hypocalcemia has never been reported. Read More

    Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation.
    J Vis Exp 2017 Mar 14(121). Epub 2017 Mar 14.
    Endocrine Unit, Massachusetts General Hospital, Harvard Medical School;
    Hypoparathyroidism (HP) is a disorder characterized by low levels of PTH which lead to hypocalcemia, hyperphosphatemia, and low bone turnover. The most common cause of the disease is accidental removal of the parathyroid glands during thyroid surgery. Novel therapies for HP are needed, but testing them requires reliable animal models of acquired HP. Read More

    Clinical characteristics of children with hemolytic uremic syndrome in Hangzhou, China.
    World J Pediatr 2017 Apr 28;13(2):183-185. Epub 2017 Mar 28.
    Department of Nephrology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
    Background: Hemolytic uremic syndrome (HUS) is a main cause of acute renal failure in children. This study aimed to analyze the clinical characteristics of HUS.

    Methods: A retrospective analysis was performed in 46 children with sporadic HUS. Read More

    [Diagnostic approach and management of hypercalcaemia in dogs exemplary of primary hyperparathyroidism].
    Tierarztl Prax Ausg K Kleintiere Heimtiere 2017 Apr 29;45(2):122-133. Epub 2017 Mar 29.
    Dr. B. Désirée Ballhausen, Tierärztliche Fachklinik für Kleintiere, Keferloher Straße 25, 85540 Haar, E-Mail:
    Hypercalcaemia can be caused by many different diseases. This article summarizes the causes, pathophysiologic mechanisms and diagnostic procedures as well as treatment recommendations. The main focus is on hypercalcaemia in primary hyperparathyroidism (PH), complemented by a case report. Read More

    Parathyroid score can predict the duration of required calcium supplementation after total thyroidectomy.
    PLoS One 2017 28;12(3):e0174088. Epub 2017 Mar 28.
    Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
    Background: Postoperative hypoparathyroidism is the most common complication after total thyroidectomy, owing to unintentional injury or decreased blood flow to the parathyroid glands. Prediction of postoperative hypoparathyroidism would be helpful for surgeons to manage postoperative hypocalcemia. In this study, we scored the discoloration of the parathyroid glands using a new parathyroid scoring system and evaluated the correlation between the parathyroid score and duration of required calcium supplementation after total thyroidectomy. Read More

    Comparative study of obstructive urolithiasis and its sequelae in buffalo calves.
    Vet World 2017 Feb 8;10(2):156-162. Epub 2017 Feb 8.
    Department of Animal Medicine (Internal Medicine), Faculty of Veterinary Medicine, Zagazig University, Egypt.
    Aim: The present work was designed to study the incidence of obstructive urolithiasis and to apply comparative diagnosis to urine retention cases.

    Materials And Methods: A total of 78 non-castrated buffalo calves aging 3-11 months were included in this study, 68 calves were admitted to the Veterinary Teaching Hospital, Zagazig University, Egypt, during the study period with a history of anuria, and they were classified into three groups; intact bladder group (19 calves), uroperitoneum group (45 calves), and ruptured urethra group (4 calves). 10 apparently healthy calves were used for comparison. Read More

    Effects of a sustained release formulation of 1,25-dihydroxyvitamin D3-glycosides for milk fever prevention on serum 1,25-dihydroxyvitamin D3, calcium and phosphorus in dairy cows.
    J Steroid Biochem Mol Biol 2017 Mar 23. Epub 2017 Mar 23.
    Institute for Animal Nutrition, Ludwig Maximilians University München, D-85764 Oberschleissheim, Germany. Electronic address:
    Milk fever (MF) is a metabolic disease in dairy cows around parturition. The clinical lead sign is muscular paresis leading in severe cases to paralysis of the affected animal. Multiparturient animals of high performing dairy breeds are most likely to be affected and have a high probability of recurrence. Read More

    1 OF 283