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    1 OF 289

    Thirty-day readmissions following parathyroidectomy: Evidence from the National Readmissions Database, 2013-2014.
    Am J Otolaryngol 2018 Jan 10. Epub 2018 Jan 10.
    University of Miami Miller School of Medicine, Miami, FL, USA.
    Purpose: Parathyroidectomy is one of the most common procedures performed in the United States, and are increasingly being performed safely in the outpatient setting. However, complications from surgery can be life-threatening, and thus an understanding of who may be at risk is essential. We analyzed and compared the risk factors for patients readmitted within 30 days following inpatient parathyroidectomy for primary or secondary hyperparathyroidism. Read More

    [Specifics of some calcium salts in intravenous therapy of hypocalcemia and their further use].
    Ceska Slov Farm 2017 ;66(4):160-163
    Hypocalcemia is a serious condition which has a major impact on the transmission of nerve impulses, contraction and relaxation of muscles (including myocardial) and pathological secretion of some hormones. The basic causal treatment is the parenteral administration of calcium, namely calcium gluconate, calcium chloride or calcium gluceptate. Parenteral formulations of these compounds must meet pharmacopoeial requirements, including the aluminum content limit. Read More

    An ICET- A survey on Hypoparathyroidism in Patients with Thalassaemia Major and Intermedia: A preliminary report.
    Acta Biomed 2018 Jan 16;88(4):435-444. Epub 2018 Jan 16.
    Quisisana Hospital, Ferrara.
    Hypoparathyroidism (HPT) is a rare disease with leading symptoms of hypocalcemia, associated with high serum phosphorus levels and absent or inappropriately low levels of parathyroid hormone (PTH). In patients with thalassemias it is mainly attributed to transfusional iron overload, and suboptimal iron chelation therapy. The main objectives of this survey were to provide data on the prevalence, demographic and clinical features of HPT in thalassemia major (TM) and intermedia (TI) patients living in different countries, and to assess its impact in clinical medical practice. Read More

    Association of Pre-ESRD Serum Calcium with Post-ESRD Mortality Among Incident ESRD Patients: a Cohort Study.
    J Bone Miner Res 2018 Jan 17. Epub 2018 Jan 17.
    Harold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California Irvine, Orange, CA, USA.
    Albumin-corrected serum calcium (cSCa) decline at late stages of chronic kidney disease and rise after dialysis initiation. While hypercalcemia is associated with higher mortality in end-stage renal disease (ESRD), there are scarce data on the impact of pre-ESRD cSCa on post-ESRD mortality. Therefore, we used a large national cohort of 21,826 US veterans with incident ESRD who transitioned to dialysis in all US Department of Veterans Affairs healthcare facilities over 2009-2014 to examine the associations with all-cause and cause-specific post-ESRD mortality of (1) cSCa concentrations averaged over the last six months and (2) its rate of decline during the last 12 months before dialysis initiation. Read More

    Prophylactic thyroidectomies in MEN2 syndrome: Management and outcomes.
    J Pediatr Surg 2017 Nov 13. Epub 2017 Nov 13.
    Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada; Department of Surgery, Division of Pediatric Surgery, CHU Sainte-Justine, Montreal, Quebec, Canada. Electronic address:
    Aim Of The Study: The aim of the study was to evaluate the outcomes of prophylactic thyroidectomies performed in an academic setting in the context of multiple endocrine neoplasia type 2 (MEN2) syndrome.

    Methods: A chart review of patients <18years old who underwent prophylactic thyroidectomy for a MEN2 syndrome at a children's hospital between 2006 and 2015 was performed.

    Main Results: The study included 21 patients (57% female) with a mean age of 6. Read More

    Risk Factors for Elevated Preoperative Alkaline Phosphatase in Patients with Refractory Secondary Hyperparathyroidism.
    Am Surg 2017 Dec;83(12):1368-1372
    Elevated preoperative levels of alkaline phosphatase (ALP) in patients with refractory secondary hyperparathyroidism are correlated with postoperative hypocalcemia and mortality. The aim of this study was to identify the predictors of preoperative ALP in patients with secondary hyperparathyroidism. From April 2012 to December 2015, 220 patients with refractory secondary hyperparathyroidism undergoing total parathyroidectomy without autotransplantation were reviewed. Read More

    Serum Parathyroid Hormone and 25-Hydroxyvitamin D Concentrations Before and After Biliopancreatic Diversion.
    Obes Surg 2018 Jan 10. Epub 2018 Jan 10.
    Endocrinology and Nephrology Unit, CHU de Québec Research Centre, Quebec City, Quebec, Canada.
    Background: Biliopancreatic diversion with duodenal switch (BPD-DS) decreases vitamin D and calcium absorption, which may result in secondary hyperparathyroidism. This study aimed at evaluating the prevalence of vitamin D deficiency and secondary hyperparathyroidism before and after BPD-DS.

    Methods: A retrospective analysis of patients who had undergone BPD-DS at a tertiary bariatric center between 2003 and 2010 and for whom simultaneous measurements of serum 25-hydroxyvitamin D and parathyroid hormone were available within 5 years post-op was performed. Read More

    The PGRIS and parathyroid splinting concepts for the analysis and prognosis of protracted hypoparathyroidism.
    Gland Surg 2017 Dec;6(Suppl 1):S86-S93
    Endocrine Surgery Unit, Hospital del Mar, Barcelona, Spain.
    Most patients with hypocalcemia after total thyroidectomy will recover the parathyroid function in a few weeks, but some 20-30% of them will still be in the need for replacement therapy one month after surgery and about 5-10% of those will develop permanent hypoparathyroidism. Although postoperative hypocalcemia has been related to several demographic and metabolic causes, parathyroid hormone (PTH) decline, resulting from autotransplantation, inadvertent excision or devascularization of the parathyroid glands, is the common final pathway. The number of parathyroid glands remaining in situ (PGRIS) is a key variable to understand the pathogenesis of protracted hypoparathyroidism and the chances for restoration of the parathyroid function. Read More

    Short and long-term impact of parathyroid autotransplantation on parathyroid function after total thyroidectomy.
    Gland Surg 2017 Dec;6(Suppl 1):S75-S85
    Endocrine Surgical Unit, University of Sydney, St Leonards, New South Wales, Australia.
    The most common complication of total thyroidectomy is parathyroid insufficiency. Acute, transient, post-operative hypoparathyroidism increases length of hospitalization, morbidity and cost associated with total thyroidectomy. While permanent hypoparathyroidism poses a significant medical burden with lifetime medication, regular follow up and considerable disease burden related to chronic renal failure and other sequelae. Read More

    Hypocalcaemia and permanent hypoparathyroidism after total/bilateral thyroidectomy in the BAETS Registry.
    Gland Surg 2017 Dec;6(Suppl 1):S69-S74
    Consultant Endocrine Surgeon, Nottingham University Hospitals, City Campus, Nottingham, UK.
    The UK Registry of Endocrine and Thyroid Surgeons (UKRETS) has been operated by the British Association of Endocrine and Thyroid Surgeons (BAETS) and Dendrite Clinical Systems Ltd. in a web-based electronic format since 2004. Data on over 90,000 endocrine procedures have been collected to date. Read More

    Incidence, prevalence and risk factors for post-surgical hypocalcaemia and hypoparathyroidism.
    Gland Surg 2017 Dec;6(Suppl 1):S59-S68
    Consultant Endocrine Surgeon, Endocrine Surgery Unit, Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
    Hypocalcaemia following thyroid surgery is common and is associated with significant short and long term morbidity. Damage to or devascularisation of parathyroid glands is the predominant underlying mechanism; although other factors such as hungry bone syndrome may occasionally contribute to it in the immediate post-operative period. The reported incidence of post-surgical hypocalcaemia and/or hypoparathyroidism (PoSH) varies significantly in the literature; the variation thought to be at least partly due to differences in the definitions used. Read More

    The role and timing of parathyroid hormone determination after total thyroidectomy.
    Gland Surg 2017 Dec;6(Suppl 1):S38-S48
    Section of Endocrine Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
    Postoperative hypocalcemia is a common complication of total thyroidectomy resulting from manipulation, resection, or devascularization of the parathyroid glands. Parathyroid hormone (PTH) levels assessed in the perioperative period have been used to predict development of hypocalcemia. Articles examining the role of PTH measurement in the perioperative period following total or completion thyroidectomy are reviewed. Read More

    To identify or not to identify parathyroid glands during total thyroidectomy.
    Gland Surg 2017 Dec;6(Suppl 1):S20-S29
    Department of Surgery, The University of Hong Kong, Hong Kong SAR, China.
    Hypoparathyroidism is one of the most common complications after total thyroidectomy and may impose a significant burden to both the patient and clinician. The extent of thyroid resection, surgical techniques, concomitant central neck dissection, parathyroid gland (PG) autotransplantation and inadvertent parathyroidectomy have long been some of the risk factors for postoperative hypoparathyroidism. Although routine identification of PGs has traditionally been advocated by surgeons, recent evidence has suggested that perhaps identifying fewer number of in situ PGs during surgery (i. Read More

    A nomogram to predict the likelihood of permanent hypoparathyroidism after total thyroidectomy based on delayed serum calcium and iPTH measurements.
    Gland Surg 2017 Dec;6(Suppl 1):S11-S19
    Endocrine Surgery Unit, University Hospital del Mar, Barcelona, Spain.
    Background: Retrospective studies have shown that delayed high-normal serum calcium and detectable iPTH are independent variables positively influencing outcome of prolonged parathyroid failure after total thyroidectomy (TT). The aim of the present study was to examine prospectively the ability of these two variables to predict permanent hypoparathyroidism in patients under replacement therapy for postoperative hypocalcemia.

    Methods: Prospective observational multicenter study of patients undergoing TT followed by postoperative parathyroid failure (serum calcium <8 mg/dL within 24 h and PTH <15 pg/mL 4 h after surgery). Read More

    Admission calcium levels and risk of acute kidney injury in hospitalised patients.
    Int J Clin Pract 2018 Jan 5. Epub 2018 Jan 5.
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
    Background: The risk of acute kidney injury (AKI) development among hospitalised patients with elevated calcium levels on admission remains unclear. The aim of this study was to assess the risk of AKI in hospitalised patients stratified by various admission serum calcium levels.

    Methods: This is a single-centre retrospective study conducted at a tertiary referral hospital. Read More

    Extracorporeal membrane oxygenation combined with continuous renal replacement therapy in cutaneous burn and inhalation injury caused by hydrofluoric acid and nitric acid.
    Medicine (Baltimore) 2017 Dec;96(48):e8972
    Department of Critical Care Medicine, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, China.
    Rationale: Hydrofluoric acid (HF) is a highly corrosive agent and can cause corrosive burns. HF can penetrate deeply into tissues through intact skin and the lipid barrier, leading to painful liquefactive necrosis, and inducing hypocalcemia and hypomagnesemia. In this study, we hypothesize that continuous renal replacement therapy (CRRT) may be beneficial in addressing hemodynamic instability in cases of HF poisoning. Read More

    Management of QT prolongation induced by anti-cancer drugs: Target therapy and old agents. Different algorithms for different drugs.
    Cancer Treat Rev 2017 Dec 6;63:135-143. Epub 2017 Dec 6.
    Division of Cardiology, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, Naples, Italy. Electronic address:
    The side effects of anticancer drugs still play a critical role in survival and quality of life. Although the recent progresses of cancer therapies have significantly improved the prognosis of oncologic patients, side effects of antineoplastic treatments are still responsible for the increased mortality of cancer survivors. Cardiovascular toxicity is the most dangerous adverse effect induced by anticancer therapies. Read More

    Does Surgery Without Lugol's Solution Pretreatment for Graves' Disease Increase Surgical Morbidity?
    World J Surg 2018 Jan 4. Epub 2018 Jan 4.
    The Department of Digestive and Endocrine Surgery, CHU Lyon Sud, Hospices Civils de Lyon, University of Lyon, 165 Chemin du Grand Revoyet, 69495, Pierre Bénite, France.
    Background: Total thyroidectomy can be performed for Graves' disease after a euthyroid state is achieved using inhibitors of thyroid hormone synthesis (thioamides). However, hypervascularization of the thyroid gland is associated with increased hemorrhage risk, in addition to complicating identification of the recurrent laryngeal nerve and parathyroid gland. Saturated iodine solution (Lugol's solution) has been recommended to reduce thyroid gland hypervascularization and intraoperative blood loss, although this approach is not used at our center based on our experience that it induces thyroid firmness and potentially hypoparathyroidism. Read More

    Comparison of indocyanine green fluorescence and parathyroid autofluorescence imaging in the identification of parathyroid glands during thyroidectomy.
    Gland Surg 2017 Dec;6(6):644-648
    Department of Endocrine Surgery, Cleveland Clinic, OH, USA.
    Background: Indocyanine green fluorescence (ICGF) and parathyroid autofluorescence (AF) are two new techniques that aid in the identification of parathyroid glands (PG) intraoperatively during thyroidectomy. There is no study comparing the efficacy of these techniques.

    Methods: This was an IRB-approved clinical study comparing the utility of ICGF and AF for identification of PGs during thyroidectomy. Read More

    TRIENNIAL LACTATION SYMPOSIUM/BOLFA: Serotonin and the regulation of calcium transport in dairy cows.
    J Anim Sci 2017 Dec;95(12):5711-5719
    The mammary gland regulates maternal metabolism during lactation. Numerous factors within the tissue send signals to shift nutrients to the mammary gland for milk synthesis. Serotonin is a monoamine that has been well documented to regulate several aspects of lactation among species. Read More

    The Importance of Networking in Pseudohypoparathyroidism: EuroPHP Network and Patient Support Associations.
    Pediatr Endocrinol Rev 2017 Nov;15(Suppl 1):92-97
    Molecular (Epi)Genetics Laboratory, BioAraba National Health Institute, Hospital Universitario Araba-Txagorritxu, Vitoria-Gasteiz, Spain.
    Pseudohypoparathyroidism is a rare endocrine disorder with an estimated prevalence of 1/100,000. It is characterized by hypocalcemia and hyperphosphatemia in the absence of vitamin D deficiency or impaired renal function. Research studies during the last 20 years have led to the identification of the molecular underlying cause of the disease, the characterization of the clinical and biochemical characteristics and the observation of an overlap between genetic and clinical manifestations. Read More

    Transcription factors that determine parathyroid development power PTH expression.
    Kidney Int 2018 Jan;93(1):7-9
    Hadassah Hebrew University Medical Center, Jerusalem, Ein Karem, Israel.
    Studies in patients with hypoparathyroidism and knockout mouse models have revealed key transcriptional cascades central for parathyroid organogenesis. Among the transcription factors essential for parathyroid development, Gata3, GCM2, and MafB, are expressed in the developing parathyroids as well as postnatally, implying that they also regulate parathyroid-specific gene expression and function in the adult. PTH gene expression is determined by transcriptional and posttranscriptional mechanisms. Read More

    One-Hour Postoperative Parathyroid Hormone Levels Do Not Reliably Predict Hypocalcemia After Thyroidectomy.
    World J Surg 2017 Dec 31. Epub 2017 Dec 31.
    Department of Surgery, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Blalock 606, Baltimore, MD, 21287, USA.
    Introduction: Hypocalcemia is a well-known complication after total thyroidectomy. Studies have indicated that the presence of low postoperative parathyroid hormone (PTH) levels can predict hypocalcemia. However, definitive study designs are lacking. Read More

    F18-fluorodeoxyglucose positron emission tomography/computed tomography for bone hemangiopericytoma.
    Mol Clin Oncol 2017 Dec 18;7(6):1147-1151. Epub 2017 Oct 18.
    Department of Radiology, Nuclear Medicine Section, Rutgers New Jersey Medical School, University Hospital, Newark, NJ 07103, USA.
    Bone hemangiopericytoma (HPC) is extremely rare, and its clinical manifestations and radiographic features are nonspecific. There are few case reports about application of F18-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in HPC. A total of four subjects with pathologically diagnosed bone HPC had FDG PET/CT for staging and/or restaging bone HPC. Read More

    Long-Term Safety of Short-Term Administration of Filgrastim (rhG-CSF) and Leukophresis Procedure in Healthy Children: Application of Peripheral Blood Stem Cell Collection in Pediatric Donors.
    Biol Blood Marrow Transplant 2017 Dec 25. Epub 2017 Dec 25.
    Children's Medical Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:
    Administration of filgrastim (recombinant human granulocyte colony-stimulating factor [rhG-CSF]) (Neupogen) in healthy donors to mobilize hematopoietic stem cells (HSCs) is a widespread practice in adults. Application of peripheral blood stem cell (PBSC) collection in normal pediatric donors is scarce due to ethical issues. Hence, there are insufficient data on the long-term impact of PBSC procedure in healthy children. Read More

    Effect of Prophylactic Calcitriol Administration on Serum Ionized Calcium Concentrations after Parathyroidectomy: 78 Cases (2005-2015).
    J Vet Intern Med 2017 Dec 27. Epub 2017 Dec 27.
    Department of Small Animal Clinical Studies, Michigan State University, East Lansing, MI.
    Background: Prophylactic administration of calcitriol has been suggested to mitigate the risk of hypocalcemia after parathyroidectomy. The effect of calcitriol on postoperative serum ionized calcium concentrations has not been evaluated in dogs after parathyroidectomy.

    Hypothesis/objectives: To determine the effect of prophylactic calcitriol administration on postoperative serum ionized calcium (iCa) concentrations in dogs with primary hyperthyroidism (PHPTH) treated by parathyroidectomy. Read More

    Hypoparathyroidism: what is the best calcium carbonate supplementation intake form?
    Braz J Otorhinolaryngol 2017 Nov 15. Epub 2017 Nov 15.
    Universidade Estadual Paulista "Júlio de Mesquita Filho" (Unesp), Faculdade de Medicina de Botucatu, Departamento de Medicina Interna, Botucatu, SP, Brazil. Electronic address:
    Introduction: In hypoparathyroidism, calcium supplementation using calcium carbonate is necessary for the hypocalcemia control. The best calcium carbonate intake form is unknown, be it associated with feeding, juice or in fasting.

    Objective: The objective was to evaluate the calcium, phosphorus and Calcium×Phosphorus product serum levels of hypoparathyroidism women after total thyroidectomy, following calcium carbonate intake in three different forms. Read More

    Perinatal complications in two cohort groups of preterm newborns in Intensive care unit for Children's Diseases of University Clinical Hospital Mostar.
    Psychiatr Danub 2017 Dec;29(Suppl 4):812-815
    Clinic of Gynecology and Obstetrics of the University Clinical Hospital Mostar, University Clinical Hospital Mostar, Bijeli Brijeg bb, 88000 Mostar, Bosnia and Herzegovina,
    Aim: To determine the frequency and type of complications in two cohort groups of preterm newborns.

    Subjects And Methods: The research involved 100 preterm newborns divided into two groups according to their gestational age: newborns from 24 to 33+6/7 weeks GA and newborns from 34 to 36+6/7 weeks GA. Parameters which were observed with mother were: age, number of births, course and complications in pregnancy. Read More

    Effects of prepartum dietary cation-anion difference and source of vitamin D in dairy cows: Health and reproductive responses.
    J Dairy Sci 2017 Dec 20. Epub 2017 Dec 20.
    Department of Animal Sciences, University of Florida, Gainesville 32611; D. H. Barron Reproductive and Perinatal Biology Research Program, University of Florida, Gainesville 32611. Electronic address:
    The objectives of the experiment were to evaluate the effects of feeding diets with distinct dietary cation-anion difference (DCAD) levels and supplemented with 2 sources of vitamin D during the prepartum transition period on postpartum health and reproduction in dairy cows. The hypotheses were that feeding acidogenic diets prepartum would reduce the risk of hypocalcemia and other diseases, and the benefits of a negative DCAD treatment on health would be potentiated by supplementing calcidiol compared with cholecalciferol. Cows at 252 d of gestation were blocked by parity (28 nulliparous and 52 parous cows) and milk yield within parous cows, and randomly assigned to 1 of 4 treatments arranged as a 2 × 2 factorial, with 2 levels of DCAD, positive (+130 mEq/kg) or negative (-130 mEq/kg), and 2 sources of vitamin D, cholecalciferol or calcidiol, fed at 3 mg for each 11 kg of diet dry matter. Read More

    Calcifediol Rather Than Cholecalciferol for a Patient Submitted to Malabsortive Bariatric Surgery: A Case Report.
    J Endocr Soc 2017 Aug 14;1(8):1079-1084. Epub 2017 Jul 14.
    Department of Clinical and Experimental Medicine, Unit of Endocrinology, University Hospital of Pisa, 56124 Pisa, Italy.
    Vitamin D deficiency following malabsorptive bariatric surgery can lead to osteomalacia. We report a patient with severe vitamin D deficiency following malabsorptive bariatric surgery successfully treated with calcifediol but not cholecalciferol. A 40-year-old woman, submitted to biliopancreatic diversion 20 years before and chronically treated with 50,000 IU cholecalciferol weekly, was admitted to our Endocrine Unit because of severe lower back pain, muscle weakness, and generalized muscular hypotrophy, associated with hypocalcemia and elevated PTH levels. Read More

    Hypocalcemia and osteomalacia after bariatric surgery.
    Clin Cases Miner Bone Metab 2017 May-Aug;14(2):227-229. Epub 2017 Oct 25.
    Endocrinologist, Practicing in Private Office, Karaj, Iran.
    Introduction: Obesity has become a major health problem not only in industrialized societies but also in developing countries. Multiple studies have shown that bariatric surgery has been effective in reducing substantial amount of weight and also the comorbidities and is being performed more frequently as an established treatment. Due to anatomical and physiological alterations after surgery that impairs absorption of vitamin D and calcium, two fundamental factors in bone formation, their intestinal absorption is highly compromised. Read More

    Effect of postparturient oral calcium administration on serum total calcium concentration in Holstein cows fed diets of different dietary cation-anion difference in late gestation.
    Res Vet Sci 2017 Nov 24;117:118-124. Epub 2017 Nov 24.
    College of Veterinary Medicine, University of Illinois, Urbana, USA.
    Minimizing the severity of post parturient hypocalcemia and the incidence of subclinical hypocalcaemia in multiparous dairy cows are important goals of the transition period. The primary objective of this study was to determine whether feeding an acidogenic ration in late gestation combined with oral CaCl2 administration after parturition improved calcium homeostasis when compared to feeding an acidogenic ration prepartum or oral CaCl2 administration postpartum alone. Forty-two Holstein dairy cows were randomly assigned to one of three groups of 14 cows. Read More

    Bisphosphonates in multiple myeloma: an updated network meta-analysis.
    Cochrane Database Syst Rev 2017 12 18;12:CD003188. Epub 2017 Dec 18.
    Center for Evidence Based Medicine and Health Outcomes Research, University of South Florida, Tampa, Florida, USA.
    Background: Bisphosphonates are specific inhibitors of osteoclastic activity and are used in the treatment of patients with multiple myeloma (MM). While bisphosphonates are shown to be effective in reducing vertebral fractures and pain, their role in improving overall survival (OS) remains unclear. This is an update of a Cochrane review first published in 2002 and previously updated in 2010 and 2012. Read More

    Trifluoroacetic acid: Three times the fluoride, three times the toxicity?
    Am J Emerg Med 2017 Dec 12. Epub 2017 Dec 12.
    Division of Medical Toxicology, University of California San Diego, San Diego, CA 92103, USA; Department of Emergency Medicine, University of California San Diego, San Diego, CA 92103, USA.
    Trifluoroacetic acid (TFAA) is a carboxylic acid, similar to acetic acid, used industrially and in laboratories. There is a paucity of data regarding exposure and the concern is that toxicity may mimic that of hydrofluoric acid (HF), causing electrolyte abnormalities, dysrhythmia, and cardiac arrest. We report a case of a 27-year-old male that presents with a dermal exposure to TFAA. Read More

    Method comparison and validation of a prototype device for measurement of ionized calcium concentrations cow-side against a point-of-care instrument and a benchtop blood-gas analyzer reference method.
    J Dairy Sci 2018 Feb 14;101(2):1334-1343. Epub 2017 Dec 14.
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853. Electronic address:
    The objective of this study was to assess an optimized ion-selective electrode Ca-module prototype as a potential cow-side device for ionized Ca (iCa) measurements in bovine blood. A linearity experiment showed no deviation from linearity over a range of iCa concentrations compared with a commercial point-of-care (POC) device commonly used in the field (POCVS; VetScan i-STAT, Abaxis North America, Union City, CA) and a laboratory gold standard benchtop blood-gas analyzer [reference analyzer (RA); ABL-800 FLEX, Radiometer Medical, Copenhagen, Denmark]. Coefficient of variation on 3 samples with high, within-range, and low iCa concentrations ranged from 1. Read More

    Prevalence of Hypocalcemia in Seizures in Infancy.
    Indian J Pediatr 2017 Dec 16. Epub 2017 Dec 16.
    KLE University, Belgaum, Karnataka, India.
    A one-year prospective study on developmentally normal children between 1-mo to 2-y with seizures was done to study the prevalence of hypocalcemia. The contribution of hypovitaminosis-D to hypocalcemia was also studied. Of 78 infants (51 boys) enrolled, 18 (23. Read More

    Video-Assisted Thyroidectomy for Papillary Thyroid Carcinoma: Oncologic Outcome in Patients with Follow-Up ≥ 10 Years.
    World J Surg 2018 Feb;42(2):402-408
    U.O.C. Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, L.go A. Gemelli 8, 00168, Rome, Italy.
    Background: Video-assisted thyroidectomy (VAT) arisen as a valid treatment for selected patients with papillary thyroid carcinoma (PTC), but no data concerning long-term oncologic outcome are available. The primary aim of the study was to evaluate the oncologic outcome of patients who underwent VAT for PTC with a follow-up ≥ 10 years.

    Methods: The medical charts of all the patients who successfully underwent VAT for PTC were reviewed. Read More

    Etelcalcetide: injectable calcimimetic for the treatment of secondary hyperparathyroidism in hemodialysis-dependent patients.
    Drugs Today (Barc) 2017 Sep;53(9):489-500
    INSERM U1132 and USPC Paris-Diderot, Department of Rheumatology, Hôpital Lariboisière, Paris, France.
    Chronic kidney disease is associated with mineral and bone disorders that are now considered as a syndrome. One of the major complications of this syndrome is secondary hyperparathyroidism (SHPT). SHPT increases bone turnover and the risk of fracture. Read More

    Persistent hypocalcemia and hungry bone syndrome after parathyroidectomy and renal transplantation in a patient with end-stage renal disease.
    Niger Med J 2017 Jan-Feb;58(1):50-52
    Students' Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
    Hungry bone syndrome (HBS) defines as persistent and severe hypocalcemia after parathyroidectomy surgery. It is treated by oral or venous discrimination of calcium carbonate. The present treatment is mostly effective. Read More

    Haemolytic anaemia and hepatocitolysis associated with hypermagnesaemia by repeated exposures to copper-calcium fungicides.
    J Enzyme Inhib Med Chem 2018 Dec;33(1):184-189
    c Faculty of Medicine , Titu Maiorescu University , Bucharest , Romania.
    For the medical practice, our manuscript acts as a signal, despite only presenting three cases which feature the association between hepatocytolysis, haemolysis and hypermagnesaemia. This clinical-biologic triad was highlighted with the workers who through the nature of their profession were exposing themselves periodically to vapours which contained copper sulphate neutralised with calcium hydroxide, a fungicide used for fruit trees. We are exclusively assessing the haematological perturbation. Read More

    Tumor Lysis Syndrome in Patients with Hematological Malignancies.
    J Oncol 2017 2;2017:9684909. Epub 2017 Nov 2.
    Department of Hematology & Immunohematology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
    Tumor lysis syndrome is a metabolic complication that may follow the initiation of cancer therapy. It commonly occurs in hematological malignant patients particularly non-Hodgkin's lymphoma and acute leukemia due to chemotherapy or spontaneously. It is characterized by a biochemical abnormality such as hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia and its clinical outcome is directly related to these biochemical abnormalities. Read More

    Georgian Med News 2017 Nov(272):118-127
    Republic of Kazakhstan, Semey State Medical University, Department of aftergraduated and additional education.
    The frequency of the combination of congenital heart defects (CHD) and connective tissue dysplasia remains poorly understood. And connective tissue dysplasia enhance severity the clinical of CHD. The aim of the study was to conduct a clinical and laboratory analysis of combinations of congenital heart defects and connective tissue dysplasia in children of Semey and to determine the risk for the development of these pathologies. Read More

    Tumor lysis syndrome with massive hyperphosphatemia and hyperuricemia.
    Clin Case Rep 2017 Dec 13;5(12):2158-2159. Epub 2017 Nov 13.
    University of FloridaGainesvilleFlorida.
    Tumor lysis syndrome (TLS) occurs when tumor cells release their contents into the bloodstream, typically in response to chemotherapy, leading to the characteristic findings of hyperuricemia, hyperkalemia, hyperphosphatemia, hypocalcemia, and acute kidney injury. Twinkle artifacts on renal ultrasound may indicate calcium phosphate deposits in such patients. Read More

    Effects of supplementation with ruminally protected choline on performance of multiparous Holstein cows did not depend upon prepartum caloric intake.
    J Dairy Sci 2018 Feb 8;101(2):1088-1110. Epub 2017 Dec 8.
    Department of Animal Sciences, University of Florida, Gainesville 32611. Electronic address:
    Objectives were to evaluate the effect of prepartum energy intake on performance of dairy cows supplemented with or without ruminally protected choline (RPC; 0 or 17.3 g/d of choline chloride; 0 or 60 g/d of ReaShure, Balchem Corp., New Hampton, NY). Read More

    Hypocalcemia Associated with Subcutaneous Fat Necrosis of the Newborn: Case Report and Literature Review.
    Oman Med J 2017 Nov;32(6):518-521
    Special Care Baby Unit, Department of Nursing Services, St Philomena Catholic Hospital, Benin City, Nigeria.
    Subcutaneous fat necrosis of the newborn (SCFNN) is a rare benign inflammatory disorder of the adipose tissue but may be complicated by hypercalcemia or less frequently, hypocalcemia, resulting in morbidity and mortality. Here we report the case of a neonate with subcutaneous fat necrosis who surprisingly developed hypocalcemia instead of hypercalcemia. A full-term female neonate was delivered by emergency cesarean section for fetal distress and was subsequently admitted to the Special Care Baby Unit. Read More

    Maternal vitamin D deficiency: A Culprit for Hypocalcaemia Induced Myocardial Failure in a Four-Month Old Infant: A Case Report From Tikur Anbessa Specialized Hospital, Ethiopia.
    Ethiop J Health Sci 2017 May;27(3):299-304
    Department Pediatrics, School of health Sciences, Addis Ababa University, Ethiopia.
    Background: A rare but reversible cause of dilated cardiomyopathy occurs in infants born to vitamin D deficient mothers due to hypocalcaemia.

    Case Report: We report a case of dilated cardiomyopathy due to hypocalcaemia secondary to maternal vitamin D deficiency in an infant presented with seizure disorder and heart failure. This was a four-month old female infant with respiratory distress and acute heart failure. Read More

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