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Medicine (Baltimore) 2022 Jun 24;101(25):e29418. Epub 2022 Jun 24.

Department of Internal Medicine, HANSUNG Union Internal Medicine Clinic and Dialysis Center, Daegu, Republic of Korea.

Rationale: Double-J stents (DJSs) are urologic devices widely used for urinary tract obstruction treatment. Perinephric abscess is a condition with purulent accumulation resulting from urinary tract infection retained between the renal capsule and Gerota's fascia. Emphysematous urinary tract infection in patients with a forgotten DJS is extremely rare. Read More

Front Immunol 2022 1;13:892534. Epub 2022 Jun 1.

Department of Clinical Pharmacology and Pharmacotherapy, KU Leuven, Leuven, Belgium.

Serum albumin (SA), the most abundant soluble protein in the body, maintains plasma oncotic pressure and regulates the distribution of vascular fluid and has a range of other important functions. The goals of this review are to expand clinical knowledge regarding the functions of SA, elucidate effects of dysregulated SA concentration, and discuss the clinical relevance of hypoalbuminemia resulting from various diseases. We discuss potential repercussions of SA dysregulation on cholesterol levels, liver function, and other processes that rely on its homeostasis, as decreased SA concentration has been shown to be associated with increased risk for cardiovascular disease, hyperlipidemia, and mortality. Read More

Data Brief 2022 Aug 6;43:108357. Epub 2022 Jun 6.

Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.

The anion gap is a calculated parameter derived from the difference between the major plasma cations and anions in serum/plasma or whole blood, with a widely used simple equation utilizing concentrations of sodium, chloride, and bicarbonate. While there is extensive literature on the clinical significance and causes of elevated anion gaps, there is comparatively less data on low anion gaps. Occasionally, anion gap calculations result in a negative number (-1 or less). Read More

Klin Lab Diagn 2022 Jun;67(6):330-333

Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation.

The aim of the study was to assess the zinc content and identify the relationship between the concentration of this element and changes in the biochemical status of patients and markers of inflammation during burn shock. We examined 23 patients aged 45.3±16. Read More

Healthcare (Basel) 2022 Jun 20;10(6). Epub 2022 Jun 20.

Medical Biology Centre, School of Nursing and Midwifery, Queen's University Belfast, 97 Lisburn Rd, Belfast BT9 7BL, UK.

Background: ESKD is a total or near-permanent failure in renal function. It is irreversible, progressive and ultimately fatal without peritoneal dialysis (PD), haemodialysis (HD) or kidney transplantation. Dialysis treatments can create new and additional problems for patients, one of which is foot amputation, as a result of non-healing wounds and vascular complications. Read More

Antibiotics (Basel) 2022 Jun 20;11(6). Epub 2022 Jun 20.

Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

bloodstream infection (SA-BSI) causes morbidity and mortality. We established a management protocol for patients with SA-BSI aimed at improving quality of care and patient outcomes. A retrospective pre-post intervention study was conducted at Maharaj Nakorn Chiang Mai Hospital from 1 October 2019 to 30 September 2020 in the pre-intervention period and from 1 November 2020 to 31 October 2021 in the post-intervention period. Read More

Animals (Basel) 2022 Jun 9;12(12). Epub 2022 Jun 9.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, Almas allé 8, 750 07 Uppsala, Sweden.

Information about prevalence and breed predisposition of canine chronic enteropathy (CE) is limited. The aim of this retrospective study was to investigate period prevalence, breed disposition, clinical features, diagnostic results, and treatment response of CE in dogs presenting at two Swedish animal hospitals during 2013-2018. A medical record search was performed to identify CE dogs including those with ≥3 visits because of gastrointestinal disease and/or that had undergone gastroduodenoscopy/colonoscopy during 2013-2018. Read More

Animals (Basel) 2022 Jun 8;12(12). Epub 2022 Jun 8.

Department of Production Animal Clinical Sciences, Norwegian University of Life Sciences, N-4325 Sandnes, Norway.

The liver fluke may cause severe infection in several mammalian species, including sheep and humans. Fasciolosis is a parasitic disease occurring worldwide in temperate climates and involves intermediate lymnaeid snails as vectors, in Europe the pond snail in particular. In the sheep industry, the disease is a serious welfare and health problem. Read More

Sci Rep 2022 Jun 23;12(1):10683. Epub 2022 Jun 23.

Department of Rheumatology and Immunology, Affiliated Nanjing Drum Tower Hospital, Medical School of Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China.

Studies on clinical features of systemic lupus erythematosus among different age-onset patients are lacking in China. This multicentre study aimed to systemically compare clinical manifestations, comorbidities, organ involvement, and laboratory findings among 797 Chinese juvenile-onset, adult-onset, and late-onset SLE (JSLE, ASLE, and LSLE) patients. They were classified into JSLE, ASLE, and LSLE groups if first diagnosed at < 18, 18-50, and > 50 years old, respectively. Read More

Spine J 2022 Jun 20. Epub 2022 Jun 20.

Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA. Electronic address:

Background Context: Spinal epidural abscess is a rare but severe condition with high rates of postoperative adverse events.

Purpose: The objective of the study was to identify independent prognostic factors for reoperation using two datasets: an institutional and national database.

Study Design/setting: Retrospective Review PATIENT SAMPLE: : Database 1: Review of five medical centers from 1993 to 2016. Read More

Rev Chilena Infectol 2022 02;39(1):20-28

Universidad tecnológica de Pereira, Pereira, Colombia.

Background: The prevalence of multi-resistant microorganisms is a public health problem that continues to grow globally. There is a population that is mainly susceptible to being colonized and subsequently infected, and these are cancer patients.

Aim: To identify the clinical and pathological characteristics of cancer patients and their relationship with infection with ESBL and CPE producing microorganisms. Read More

Expert Rev Clin Pharmacol 2022 Jun 26:1-11. Epub 2022 Jun 26.

Department of Clinical Pharmacy, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Introduction: Antibiotic prescription is a challenging issue in critical care settings. Different pharmacokinetic and pharmacodynamic properties, polypharmacy, drug interactions, and high incidence of multidrug-resistant microorganisms in this population can influence the selection, safety, and efficacy of prescribed antibiotics.

Areas Covered: In the current article we searched PubMed, Scopus and Google Scholar for neurotoxicities, hematologic toxicity and fluid stewardship in intensive care units. Read More

Ann Med Surg (Lond) 2022 Jun 31;78:103891. Epub 2022 May 31.

Nepalese Army Institute of Health and Sciences, Kathmandu, Nepal.

Introduction: Polyserositis in disseminated tuberculosis (TB) is an uncommon presentation. The exudative nature of effusion in disseminated TB can be masked by presence of malnutrition due TB.

Case Presentation: A 24-year-old female, diagnosed with disseminated TB, developed polyserositis with transudative nature of fluid. Read More

Front Pediatr 2022 30;10:875032. Epub 2022 May 30.

Department of Nephrology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Protein-losing enteropathy (PLE) is a clinical disorder in which an excessive amount of serum protein is lost into the gastrointestinal tract, resulting in hypoproteinemia and malnutrition. PLE is associated with a wide range of gastrointestinal disorders and the rare complication of constrictive pericarditis. We report a case in which pericardiectomy achieved marked improvement of extremely severe hypoalbuminemia caused by PLE associated with tuberculosis-related constrictive pericarditis. Read More

Maedica (Bucur) 2022 Mar;17(1):153-168

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Nephrotic syndrome is a rare condition with an incidence of 2-7 cases/100.000 children per year and three new cases/100.000 adults per year. Read More

J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096221104465

Medical College of Georgia, Augusta, USA.

A healthy 11-year-old girl presents with epigastric abdominal pain, fever, weight loss, and decreased appetite for 1 month. On physical examination, she appears ill, dehydrated, and cachectic. Her abdominal examination is significant for large ascites with a fluid wave and is nontender to palpation. Read More

J Taibah Univ Med Sci 2022 Jun 9;17(3):376-383. Epub 2021 Nov 9.

College of Agriculture and Biotechnology, Provincial Resources, Zhejiang University, Hangzhou, China.

Objective: Chronic kidney disease and/or disturbance in renal excretory function may lead to nitrogenous waste collection beyond the term as well as derangements of several serum biochemicals. There is no previous study from Pakistan that reveals serum electrolyte derangements in confirmed chronic kidney disease (CKD) patients and other biochemicals associated with CKD. This study aims to examine the derangements of serum biochemicals and the association of several risk factors with CKD. Read More

Cureus 2022 May 16;14(5):e25061. Epub 2022 May 16.

Clinical Medicine, QU Health, Qatar University, Doha, QAT.

Adrenal insufficiency is a rare disorder that results from etiological factors affecting either the hypothalamic-pituitary axis or the adrenal gland itself. Studies have associated an inherently increased risk of cardiovascular events with this condition. It is treated with exogenous steroid supplementation. Read More

Indian J Crit Care Med 2022 May;26(5):626-631

Department of Anaesthesiology, AIIMS Patna, Patna, Bihar, India.

Introduction: We researched blood urea nitrogen (BUN), albumin and their ratio (BAR), and compared them with C-reactive protein (CRP), D-dimer, and computed tomography severity scores (CT-SS), to predict in-hospital mortality.

Methods: One-hundred and thirty-one coronavirus disease-2019 (COVID-19) confirmed patients brought to the emergency department (ED) were dispensed to the survivor or non-survivor group, in light of in-hospital mortality. Information on age, gender, complaints, comorbidities, laboratory parameters, and outcome were gathered from the patient's record files. Read More

Infect Agent Cancer 2022 Jun 18;17(1):33. Epub 2022 Jun 18.

Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue, Guangzhou, China.

Background: The prognostic value of serum albumin in acquired immunodeficiency syndrome (AIDS)-related lymphoma (ARL) remains covered.

Methods: We retrospectively analyzed de novo ARL patients from 2013 to 2019 across three centers. Factors correlated with progression-free survival (PFS) and overall survival (OS) were evaluated in Kaplan-Meier, univariate and multivariate Cox proportional hazard models. Read More

J Gynecol Oncol 2022 Jun 7. Epub 2022 Jun 7.

Department of Gynecologic Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Objective: Advances in ovarian cancer cytoreductive surgery have enabled more extensive procedures to achieve maximal cytoreduction but with a consequent increase in postoperative morbidity and mortality. The aim of this study was to evaluate factors for postoperative morbidity after extensive cytoreductive surgery for primary epithelial ovarian cancer (EOC), particularly those which may be modifiable.

Methods: Electronic databases were searched. Read More

J Formos Med Assoc 2022 Jun 11. Epub 2022 Jun 11.

Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.

Background: Although blood test is a routine in major burns, its relationship with burn size and intensive care unit length of stay (ICULOS) remains undetermined. We investigated the feasibility of using these tests as a reference for definite diagnosis of major burn size, burn size >20% of the total body surface area (TBSA), and their relationships with ICULOS.

Methods: Data of routine laboratory blood tests within 24 h after burns (n = 73) were collected retrospectively. Read More

Respir Med 2022 Jun 4;200:106898. Epub 2022 Jun 4.

Department of Respiratory Medicine, National Hospital Organization Fukuoka National Hospital, 4-39-1 Yakatabaru, Minami-ku, Fukuoka City, Fukuoka, 811-1394, Japan.

Background: Several studies have reported that acute exacerbation (AE), which occurs during the clinical course of idiopathic pulmonary fibrosis (IPF), also occurs in rheumatoid arthritis-associated interstitial lung disease (RA-ILD). However, the incidence, clinical features, and risk factors for AE, a major cause of death of RA-ILD patients, and the differences in clinical aspects of AE between RA-ILD and IPF have yet to be fully understood.

Methods: We retrospectively reviewed data on 149 RA-ILD patients and 305 IPF patients. Read More

J Long Term Eff Med Implants 2022 ;32(2):35-43

Department of Orthopaedic Surgery and Rehabilitation Medicine, State University of New York, Downstate Medical Center/University Hospital Brooklyn, Brooklyn, New York 11203; New York City Health and Hospitals/Kings County, Brooklyn, New York 11203.

There is a lack of understanding of risk factors and postoperative outcomes of syndesmotic injuries with singular versus multipart fractures. A retrospective analysis was done between 2008 and 2016, utilizing the American College of Surgeons National Surgical Improvement Program database. Patients with open reduction and internal fixation of isolated lateral malleolus fractures, bimalleolar fractures, or trimalleolar fractures were identified. Read More

World Neurosurg 2022 Jun 9. Epub 2022 Jun 9.

Department of Neurosurgery, Baylor Scott & White Health, Scott and White Medical Center, Temple, Texas, USA; Department of Surgery, Texas A&M University College of Medicine, Temple, Texas, USA.

Background: The prevalence of carotid artery atherosclerosis and stroke is increasing. Carotid artery stenting (CAS), which treats carotid artery stenosis and prevents strokes, has benefited from advances in techniques and technology. In this study, we aimed to identify significant risk factors for major complications following contemporary CAS. Read More

BMC Musculoskelet Disord 2022 Jun 10;23(1):564. Epub 2022 Jun 10.

Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Jiangxi, People's Republic of China.

Background: Recent studies suggest that routine laboratory tests are not required within 1 day after partial knee arthroplasty. In this study, we evaluated the utility of routine postoperative laboratory tests after initial unilateral total knee arthroplasty (TKA) in an Asian population. In addition, we explored risk factors associated with abnormal test results. Read More

J Vet Diagn Invest 2022 Jun 10:10406387221101547. Epub 2022 Jun 10.

Department of Veterinary Sciences, University of Pisa, Pisa, Italy.

Serum protein electrophoresis (SPE) shows the distribution of protein fractions, helping clinicians to characterize some pathologic processes. Information is lacking in the literature about SPE alterations in dogs with chronic hepatitis (CH). Our aim was to describe SPE alterations in canine CH, to compare SPE results to histologic scores, and to study SPE trends during follow-up. Read More

Braz J Biol 2022 3;84:e257179. Epub 2022 Jun 3.

University of Agriculture Faisalabad, Department of Forestry and Range Management, Faisalabad, Pakistan.

Avian pathogenic Escherichia coli (APEC) induces colibacillosis, an acute and systemic disease, resulting in substantial economic losses in the poultry sector. This study aimed to investigate the antibiotic resistance pattern associated with frequent virulence gene distribution in APEC O78:K80 that may cause pathological alterations in chickens. The antibiogram profile showed high resistance to erythromycin, chloramphenicol, tetracycline, ampicillin, and co-trimoxazole, followed by intermediate resistance to ciprofloxacin, levofloxacin, enrofloxacin, norfloxacin, nitrofurantoin, and doxycycline hydrochloride, and sensitive to amikacin, streptomycin, gentamicin, and colistin. Read More

Vet Radiol Ultrasound 2022 Jun 8. Epub 2022 Jun 8.

Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA.

Postcontrast computed tomographic (CT) characteristics of gastrointestinal (GI) wall edema in humans have been described as GI wall thickening with a thickened submucosal layer and thin enhanced inner and outer layers. Published studies describing CT features of gastric wall edema in dogs are currently lacking. The aim of this retrospective, case series was to describe CT features of gastric wall edema in a group of dogs. Read More

Surg Neurol Int 2022 6;13:193. Epub 2022 May 6.

Department of Orthopaedics, University of California Irvine, Orange, California, United States.

Background: We analyzed the role of hypoalbuminemia, dialysis, and other risk factors that increase morbidity/ mortality following surgery for primary pyogenic spinal infections (PSIs). The American College of Surgeons' National Surgical Quality Improvement Program (ACS-NSQIP) that included 627 patients was utilized as our database.

Methods: Primary spinal surgery for spondylodiscitis was evaluated in a ACS-NSQIP database involving 627 patients between 2010 and 2019. Read More