A Prospective Single-Arm Trial of Modified Long Biliopancreatic and Short Alimentary Limbs Roux-En-Y Gastric Bypass in Type 2 Diabetes Patients with Mild Obesity.
- Abdon José Murad,
- Ricardo Vitor Cohen,
- Eudes Paiva de Godoy,
- Christian Lamar Scheibe,
- Giuliano Peixoto Campelo,
- Almino Cardoso Ramos,
- Roclides Castro de Lima,
- Luís Eduardo Veras Pinto,
- Daniel Coelho,
- Hamilton Belo França Costa,
- Ígor Marreiros Pereira Pinto,
- Tiago Pereira,
- Francisco Raúl Santos Teófilo,
- José Aparecido Valadão
Obes Surg 2017 Sep 20. Epub 2017 Sep 20.
Center for Bariatric and Metabolic Surgery, São Domingos Hospital, São Luís, Brazil.
Background: Type-2 diabetes (T2D) patients with body mass index (BMI) below 35 kg/m(2) carry lower remission rates than severely obese T2D individuals submitted to "standard limb lengths" Roux-en-Y gastric bypass (RYGB). Mild-obese patients appear to have more severe forms of T2D, where the mechanisms of glycemic control after a standard-RYGB may be insufficient. The elongation of the biliopancreatic limb may lead to greater stimulation of the distal intestine, alterations in bile acids and intestinal microbiota, among other mechanisms, leading to better metabolic outcomes. Read More