277 results match your criteria Hyperthyroidism Thyroid Storm and Graves Disease


Simultaneous presentation of thyroid storm and diabetic ketoacidosis in a previously healthy 21-year-old man.

BMJ Case Rep 2019 Jan 28;12(1). Epub 2019 Jan 28.

Department of Biomedical Sciences, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, Michigan, USA.

A 21-year-old young man with no history of diabetes or thyroid disease presented to the emergency department with simultaneous thyroid storm and diabetic ketoacidosis. Notable findings on admission were a ventricular rate of 235 beats/min, tachypnoea, tremors, polydipsia and a lack of fever. Due to the unusual constellation of symptoms, diagnosis was only possible after initial laboratory results came back. Read More

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http://dx.doi.org/10.1136/bcr-2018-227554DOI Listing
January 2019
1 Read

Acute Thyroid Storm Following Thymectomy: A Surprising Result of Undiagnosed Graves' Disease.

Cureus 2018 Aug 31;10(8):e3239. Epub 2018 Aug 31.

Surgery, University of Texas Medical Branch, Galveston, USA.

Postoperative thyroid storm represents a diagnostic dilemma in patients with overlooked hyperthyroid state undergoing a nonthyroid surgery. We report a 30-year-old female with a history of mixed connective tissue disease who presented with an anterior mediastinal mass and underwent a thoracoscopic resection of the mass. On postoperative day 1, she had an acute change in mental status with fever, tachycardia and hypercapnic respiratory failure requiring intubation and mechanical ventilation. Read More

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http://dx.doi.org/10.7759/cureus.3239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209514PMC
August 2018
12 Reads

Weathering the storm: A case of thyroid storm refractory to conventional treatment benefiting from therapeutic plasma exchange.

J Clin Apher 2018 Dec 15;33(6):678-681. Epub 2018 Oct 15.

Department of Pathology, Division of Transfusion Medicine, University of Texas Medical Branch, Galveston, Texas.

Thyroid storm is a severe manifestation of thyrotoxicosis characterized by systemic organ dysfunction secondary to a hypermetabolic state. Although antithyroid drugs, steroids, beta-blockers, antipyretics, and cholestyramine are the standard of care, some patients inadequately respond to these conventional therapies. Therapeutic plasma exchange has been previously utilized as a treatment modality in patients with a poor response to routine therapies or with contraindications to them. Read More

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http://dx.doi.org/10.1002/jca.21658DOI Listing
December 2018
1 Read

Thyroid storm following rapid sequence intubation.

Am J Emerg Med 2018 Dec 3;36(12):2338.e5-2338.e6. Epub 2018 Sep 3.

Department of Emergency Medicine, University of Texas Health Science Center at San Antonio, United States of America. Electronic address:

Thyroid storm is a rare complication with an estimated incidence ranging from 0.61 to 0.76 cases per 100,000 people. Read More

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http://dx.doi.org/10.1016/j.ajem.2018.09.006DOI Listing
December 2018
5 Reads

[Thyroid storm and diabetic ketoacidosis (DKA) in a previously healthy male - a significant differential diagnostic challenge].

Lakartidningen 2018 08 24;115. Epub 2018 Aug 24.

Medicinkliniken, Hallands sjukhus Halmstad - Halmstad, Sweden Medicinkliniken, Hallands sjukhus Halmstad - Halmstad, Sweden.

Thyroid storm is a potentially lethal condition sometimes seen in cases of untreated thyrotoxicosis. Hypermetabolism, fever, and tachycardia are typical symptoms of the increased thyroid hormone activity. Thyroid storm is often triggered by infection, trauma or recent surgery and rarely by other causes. Read More

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August 2018
3 Reads

Thyrotoxic Periodic Paralysis and Cardiomyopathy in a Patient with Graves' Disease.

Cureus 2018 Jun 19;10(6):e2837. Epub 2018 Jun 19.

Critical Care, Maimonides Medical Center, Brooklyn, USA.

Thyrotoxic periodic paralysis (TPP) and cardiomyopathy are two established complications of thyrotoxicosis. Emergent management is essential as TPP and cardiac events secondary to thyrotoxic cardiomyopathy can be fatal. We report a unique case of a patient with Graves' disease presenting with symptoms secondary to both these complications. Read More

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http://dx.doi.org/10.7759/cureus.2837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101465PMC
June 2018
4 Reads

Thyroid Storm and Complete Heart Block after Treatment with Radioactive Iodine.

Case Rep Endocrinol 2018 11;2018:8214169. Epub 2018 Jun 11.

Division of Endocrinology and Diabetes, The Robert Larner, M.D. College of Medicine, The University of Vermont, Burlington, VT, USA.

Thyroid storm is a rare endocrine emergency characterized by dysfunction of multiple organ systems. Thyroid storm is more common in Graves' disease and can be precipitated by surgery, trauma, infection, metabolic abnormalities, iodine load, and parturition. We present a diagnostically challenging case of thyroid storm precipitated by radioiodine therapy and accompanied by bradycardia, a rare but life-threatening complication related to treatment for hyperthyroidism. Read More

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https://www.hindawi.com/journals/crie/2018/8214169/
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http://dx.doi.org/10.1155/2018/8214169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016161PMC
June 2018
11 Reads

Therapeutic plasmapheresis in thyrotoxic patients.

Endocrine 2018 10 2;62(1):144-148. Epub 2018 Jul 2.

Ege University Medical Faculty, Division of Endocrinology and Metabolism Disorders, Izmir, Turkey.

Purpose: For the treatment of thyrotoxicosis, alternative treatment modalities may be necessary if anti-thyroid drugs cannot be used due to side effects, inefficiencies, or there is a need to start a rapid action such as thyroid storm. By using therapeutic plasma exchange (TPE), it is possible to effectively and rapidly remove the increased thyroid hormones. We evaluated our results and experience on a rapid, effective, and reliable alternative treatment modality in thyrotoxic patients. Read More

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http://dx.doi.org/10.1007/s12020-018-1661-xDOI Listing
October 2018
6 Reads

Does thyrotoxic periodic paralysis have a genetic predisposition? A case report.

Ann Clin Biochem 2018 Nov 20;55(6):713-716. Epub 2018 Jul 20.

1 Department of Clinical Chemistry, Tallaght University Hospital, Tallaght, Dublin, Ireland.

Thyrotoxic periodic paralysis is a rare complication of hyperthyroidism where increased influx of potassium into skeletal muscle cells leads to profound hypokalaemia and paralysis. Most cases arise sporadically in Asians; however, it is being increasingly reported in Caucasians. It is regarded as a channelopathy where a genetic and/or acquired defect in the sodium-potassium (Na/K-ATPase) pump renders it more sensitive to excess thyroid hormone in susceptible individuals. Read More

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http://dx.doi.org/10.1177/0004563218785395DOI Listing
November 2018
34 Reads

A retrospective cohort study: do patients with graves' disease need to be euthyroid prior to surgery?

J Otolaryngol Head Neck Surg 2018 May 21;47(1):37. Epub 2018 May 21.

Department of Otolaryngology - Head and Neck surgery, Jewish General Hospital, McGill University, 3755 Côte-Sainte-Catherine Road, Montreal, Quebec, H3T 1E2, Canada.

Background: The 2016 American Thyroid Association guidelines indicate that patients with Graves' disease who undergo a thyroidectomy should be rendered euthyroid through the use of antithyroid drugs (ATD) prior to surgery to avoid complications such as a thyroid storm. At times, the use of ATDs can have limited efficacy and therefore some patients will inevitably remain biochemically hyperthyroid at the time of surgery. The aim of this study is to assess if hyperthyroid patients undergoing a thyroidectomy are at an increased risk of developing a thyroid storm in comparison to euthyroid patients. Read More

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http://dx.doi.org/10.1186/s40463-018-0281-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963139PMC
May 2018
4 Reads

Type 2 Diabetes Decompensation as the Clinical Presentation of Thyroid Storm - Cause or Consequence?

Eur Endocrinol 2017 Aug 22;13(2):99-101. Epub 2017 Aug 22.

Endocrinology Department, Hospital de Braga, Braga, Portugal.

This case study aims to discuss the unusual forms of hyperthyroidism presentation, the nonspecific symptoms and precipitating events. A 70-year-old male was taken to the emergency department for hyperglycaemia, nausea, vomiting and altered mental status with a week of evolution. He had a past medical history of type 2 diabetes, hypertension and dyslipidemia. Read More

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http://www.touchendocrinology.com/articles/type-2-diabetes-d
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http://dx.doi.org/10.17925/EE.2017.13.02.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813473PMC
August 2017
11 Reads

Thyrotoxic crisis as an acute clinical presentation in a child.

BMJ Case Rep 2018 Mar 23;2018. Epub 2018 Mar 23.

Paediatrics, University Hospitals of Leicester Foundation Trust, Leicester, UK.

A previously well, 4-year-old girl presented with a 4-6 weeks' history of increased appetite, weight loss, tiredness, sleep difficulty, excessive sweating, swelling in the neck and new-onset 'prominent, protruding eyes.' Family history revealed paternal grandmother receiving treatment for hyperthyroidism. Clinical assessment demonstrated features of thyrotoxicosis (tachycardia, warm peripheries, small smooth goitre with no nodules, exophthalmos). Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22285
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http://dx.doi.org/10.1136/bcr-2017-222850DOI Listing
March 2018
23 Reads

More, less or both?

BMJ Case Rep 2018 Mar 5;2018. Epub 2018 Mar 5.

Department of Internal medicine, VU Medical Center, Amsterdam, The Netherlands.

A 67-year-old Caucasian woman with no prior medical history was admitted to our hospital with complaints of generalised weakness, nausea, diarrhoea and weight loss. The patient suffered from tachycardia and hypotension. Blood tests revealed Graves' thyrotoxicosis and the patient was treated accordingly. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22235
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http://dx.doi.org/10.1136/bcr-2017-222355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847917PMC
March 2018
3 Reads

Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm.

Intern Med 2018 Jul 28;57(13):1939-1942. Epub 2018 Feb 28.

Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan.

We herein report a case of central diabetes insipidus complicated with thyroid storm. A middle-aged woman who was receiving treatment for Graves' disease suddenly complained of polydipsia, polyuria and general fatigue. Laboratory tests showed hyperthyroidism, hypernatremia, hypoosmolar urine and a decreased plasma vasopressin level. Read More

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http://dx.doi.org/10.2169/internalmedicine.0063-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064704PMC
July 2018
11 Reads

Cytomegalovirus-mononucleosis-induced thyroiditis in an immunocompetent patient.

Endocrinol Diabetes Metab Case Rep 2017 24;2017. Epub 2017 Nov 24.

Division of Endocrinology, Jewish General Hospital, Montréal, Québec, Canada.

Enteroviruses, including coxsackieviruses and Echovirus, are well known pathogens responsible for the development of thyroiditis. We describe the case of a 49-year-old woman with no personal or family history of thyroid disease who presented to the emergency room with a two-week history of daily fevers up to 39°C, a sore throat, occasional palpitations and diaphoresis, decreased appetite and an unintentional 10 kg weight loss over the same time course Physical examination revealed mild tachycardia, an intention tremor and a normal-sized, nontender thyroid gland without palpable nodules. The remainder of the physical examination was unremarkable and without stigmata of Graves' disease. Read More

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http://dx.doi.org/10.1530/EDM-17-0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704440PMC
November 2017
7 Reads

Preoperative management in patients with Graves' disease.

Gland Surg 2017 Oct;6(5):476-481

Department of Medicine and Surgery, University of Insubria, Varese, Italy.

Graves' disease is the most frequent cause of hyperthyroidism in iodine-sufficient geographical areas and is characterized by the presence in patients' serum of autoantibodies directed against the thyrotropin receptor (TRAb) that cause overproduction and release of thyroid hormones. Clinical presentation results from both hyperthyroidism and underlying autoimmunity. The diagnosis is based on characteristic clinical features and biochemical abnormalities. Read More

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http://dx.doi.org/10.21037/gs.2017.05.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676164PMC
October 2017
7 Reads

Iodinated Contrast Administration Resulting in Cardiogenic Shock in Patient with Uncontrolled Graves Disease.

J Emerg Med 2017 Dec 6;53(6):e125-e128. Epub 2017 Nov 6.

Virginia Tech Carilion Emergency Medicine Residency, Department of Emergency Medicine, Virginia Tech Carilion School of Medicine, Roanoke, Virginia.

Background: Thyroid storm (also known as thyroid or thyrotoxic crisis) is part of the spectrum of thyrotoxicosis and represents the extreme end of that spectrum. The condition is quite rare, yet mortality rates are high and may approach 10-30%.

Case Report: A 34-year-old-man who had a history of Graves disease presented in atrial fibrillation with rapid ventricular response and mild congestive heart failure. Read More

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http://dx.doi.org/10.1016/j.jemermed.2017.08.096DOI Listing
December 2017
8 Reads

Total Thyroidectomy for Thyroid Cancer Followed by Thyroid Storm due to Thyrotropin Receptor Antibody Stimulation of Metastatic Thyroid Tissue.

Eur Thyroid J 2017 Sep 3;6(5):276-280. Epub 2017 Aug 3.

Department of Endocrinology, Odense University Hospital, Odense, Denmark.

Background: Graves disease (GD) is an autoimmune condition characterized by the presence of antibodies against the thyrotropin receptor (TRAB), which stimulate the thyroid gland to produce excess thyroid hormone. Theoretically, TRAB could stimulate highly differentiated thyroid cancer tissue and/or metastases to produce thyroid hormone.

Case: A 68-year-old male, with weight loss and palpitations, was diagnosed with thyrotoxicosis. Read More

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http://dx.doi.org/10.1159/000479061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649237PMC
September 2017
24 Reads

Malignant Hyperthermia Versus Thyroid Storm in a Patient With Symptomatic Graves Disease: A Case Report.

A A Pract 2018 Mar;10(5):97-99

From the Department of Anesthesiology, Loyola University Medical Center, Maywood, Illinois.

Malignant hyperthermia and thyroid storm are intraoperative emergencies with overlapping symptoms but different treatment protocols. We faced this diagnostic dilemma in a 25-year-old patient with symptomatic hyperthyroidism, elevated free T3 and free T4, and low thyroid-stimulating hormone from Graves disease despite treatment with propranolol 80 mg daily and methimazole 40 mg every 8 hours. During thyroidectomy, he developed hyperthermia and hypercarbia without tachycardia. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000639DOI Listing
March 2018
9 Reads

Thyroid storm and warm autoimmune hemolytic anemia.

Transfus Apher Sci 2017 Aug 18;56(4):606-608. Epub 2017 Aug 18.

Division of Hematology Oncology, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX, United States.

Graves' disease is often associated with other autoimmune disorders, including rare associations with autoimmune hemolytic anemia (AIHA). We describe a unique presentation of thyroid storm and warm AIHA diagnosed concurrently in a young female with hyperthyroidism. The patient presented with nausea, vomiting, diarrhea and altered mental status. Read More

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http://dx.doi.org/10.1016/j.transci.2017.08.003DOI Listing
August 2017
14 Reads

[Thyroid storm associated with multiorganic dysfunction].

Medicina (B Aires) 2017 ;77(4):337-340

Servicio de Endocrinología, Fundación Valle del Lili, Cali, Colombia. E-mail:

Thyroid storm is a rare and potentially fatal condition. Unusual presentations in patients with thyroid storm have been described but multiorganic dysfunction is uncommonly seen. We describe the case of a 36-year-old woman with unknown underlying Graves's disease who developed thyroid storm. Read More

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July 2018
56 Reads

Early Timing of Thyroidectomy for Hyperthyroidism in Graves' Disease Improves Biochemical Recovery.

World J Surg 2017 10;41(10):2545-2550

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich and University of Zurich, Frauenklinikstrasse 24, 8091, Zurich, Switzerland.

Background: The role of thyroidectomy as an early treatment for hyperthyroidism has been poorly investigated. Our aim was to examine its success rates, particularly focusing on thyroidectomy as an early treatment.

Methods: Patients with thyroidectomy for hyperthyroidism between February 2008 and October 2014 were included. Read More

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http://dx.doi.org/10.1007/s00268-017-4052-1DOI Listing
October 2017
31 Reads

Lugol's solution-induced painless thyroiditis.

Endocrinol Diabetes Metab Case Rep 2017 30;2017. Epub 2017 May 30.

Division of Endocrinology and Metabolism, Department of Medicine, McGill University Health Centre, Montreal, QuebecCanada.

Lugol's solution is usually employed for a limited period for thyroidectomy preparation in patients with Graves' disease and for the control of severe thyrotoxicosis and thyroid storm. We describe a rare case of Lugol's solution-induced painless thyroiditis. In November 2014, a 59-year-old woman was prescribed Lugol's solution four drops per day for the alleviation of menopausal symptoms. Read More

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http://dx.doi.org/10.1530/EDM-17-0034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467656PMC
May 2017
20 Reads

Successful treatment of thyroid storm presenting as recurrent cardiac arrest and subsequent multiorgan failure by continuous renal replacement therapy.

Endocrinol Diabetes Metab Case Rep 2017 31;2017. Epub 2017 Mar 31.

Division of Nephrology, Kosin University College of Medicine, BusanRepublic of Korea.

Summary: Thyroid storm is a rare and potentially life-threatening medical emergency. We experienced a case of thyroid storm associated with sepsis caused by pneumonia, which had a catastrophic course including recurrent cardiac arrest and subsequent multiple organ failure (MOF). A 22-year-old female patient with a 10-year history of Graves' disease was transferred to our emergency department (ED). Read More

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https://edm.bioscientifica.com/view/journals/edm/2017/1/EDM1
Publisher Site
http://dx.doi.org/10.1530/EDM-16-0115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404465PMC
March 2017
23 Reads

Hyperthyroidism-associated hypercalcemic crisis: A case report and review of the literature.

Medicine (Baltimore) 2017 Jan;96(4):e6017

Department of Endocrinology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China.

Rationale: Hyperthyroidism is one of the major clinical causes of hypercalcaemia, however, hyperthyroidism-related hypercalcemic crisis is rare, only 1 case have been reported. The potential mechanisms are still not too clear. It may be related that thyroid hormone stimulate bone turnover, elevate serum calcium, increase urinary and fecal calcium excretion. Read More

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http://dx.doi.org/10.1097/MD.0000000000006017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287984PMC
January 2017
19 Reads

Thyroid Storm Precipitated by Diabetic Ketoacidosis and Influenza A: A Case Report and Literature Review.

Intern Med 2017 15;56(2):181-185. Epub 2017 Jan 15.

Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center, Japan.

A 46-year-old woman with a history of Graves' disease presented with the chief complaints of appetite loss, weight loss, fatigue, nausea, and sweating. She was diagnosed with diabetic ketoacidosis (DKA), thyroid storm, and influenza A. She was treated with an intravenous insulin drip, intravenous fluid therapy, intravenous hydrocortisone, oral potassium iodine, and oral methimazole. Read More

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http://dx.doi.org/10.2169/internalmedicine.56.7593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337464PMC
March 2017
16 Reads

A case of fatal heart and liver failure accompanied by thyroid storm treated with prompt plasma exchange.

J Cardiol Cases 2017 Mar 17;15(3):100-103. Epub 2017 Jan 17.

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

A 36-year-old man with a history of Graves' disease was admitted complaining of dyspnea. He was diagnosed with acute heart failure and severe liver dysfunction accompanied by thyroid storm. Left ventricular ejection fraction was 19%, and liver enzyme levels were markedly elevated followed with coagulation disorders. Read More

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http://dx.doi.org/10.1016/j.jccase.2016.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135025PMC

An autopsy case of hyperthyroid cardiomyopathy manifesting lethal congestive heart failure.

Pathol Int 2017 Feb 23;67(2):110-112. Epub 2016 Dec 23.

Department of Pathology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan.

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http://dx.doi.org/10.1111/pin.12491DOI Listing
February 2017
6 Reads

Association of KCNJ2 Genetic Variants with Susceptibility to Thyrotoxic Periodic Paralysis in Patients with Graves' Disease.

Exp Clin Endocrinol Diabetes 2017 Feb 22;125(2):75-78. Epub 2016 Dec 22.

Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

Thyrotoxic periodic paralysis (TPP) is characterized by acute onset paralysis and hypokalemia predominantly in male patients with thyrotoxicosis. Recent studies have emphasized the importance of potassium channels, which might explain the underlying mechanism of TPP. The gene encodes the inward-rectifying potassium channel. Read More

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http://dx.doi.org/10.1055/s-0042-119527DOI Listing
February 2017
79 Reads

A case of hypercalcaemic crisis secondary to coexistence of primary hyperparathyroidism and Graves' disease.

Endocr Regul 2016 Oct;50(4):225-228

A 46 year-old female patient presented to the hospital with ongoing and progressively increasing fatigue, severe nausea and vomiting, loss of appetite, constipation, palpitations and somnolence. Laboratory evaluation revealed a severe hypercalcaemia and overt hyperthyroidism. She was diagnosed with primary hyperparathyroidism accompanied by Graves' disease. Read More

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http://dx.doi.org/10.1515/enr-2016-0024DOI Listing
October 2016
15 Reads

A Case of Thyroid Storm Associated with Cardiomyopathy and Poststreptococcal Glomerulonephritis.

Case Rep Pediatr 2016 27;2016:7192359. Epub 2016 Oct 27.

Department of Pediatric Endocrinology and Diabetes and Department of Pediatric Nephrology, The Children's Hospital at Montefiore, 3415 Bainbridge Ave., Bronx, NY 10467, USA.

Thyroid storm has a high mortality rate and is often associated with a precipitating factor such as intercurrent illness or infection. It is rare in pediatric patients. Cardiac disease in hyperthyroidism mostly manifests itself as tachycardia but more serious cardiac findings have also been described. Read More

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http://dx.doi.org/10.1155/2016/7192359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102721PMC
October 2016
19 Reads

Low cardiac output thyroid storm in a girl with Graves' disease.

Pediatr Int 2016 Oct;58(10):1080-1083

Division of Endocrinology and Metabolism, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

A 15-year-old girl with Graves' disease presented with hypotension after methimazole and propranolol were re-started for hyperthyroidism. She was found to have pulmonary artery hypertension resulting in obstructive shock. Thyroid storm was diagnosed according to Burch and Wartofsky score. Read More

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http://dx.doi.org/10.1111/ped.13102DOI Listing
October 2016
11 Reads

Thyroid Storm Precipitated by Radioactive Iodine Therapy.

J Assoc Physicians India 2015 Dec;63(12):95-96

Registrar, Seth G.S. Medical College & K.E.M.H., Mumbai, Maharashtra.

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December 2015
1 Read

Antithyroid drugs during breastfeeding.

Clin Endocrinol (Oxf) 2016 Dec 22;85(6):827-830. Epub 2016 Sep 22.

Department of Nutrition-Related Disease Prevention, School of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland.

Antithyroid drugs (ATDs) are widely used for the treatment of Graves' disease (GD) in the general population. Over the past decade, there has been an increasing awareness that several disturbances of thyroid function may occur in mothers after delivery which may be more prevalent than previously appreciated. Exacerbation of immune reactions occurs 3-12 month following delivery. Read More

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http://dx.doi.org/10.1111/cen.13176DOI Listing
December 2016
11 Reads

[Endocrine and Metabolic Emergencies; Points of Initial Management. Topics: III. Thyroid storm].

Authors:
Takashi Akamizu

Nihon Naika Gakkai Zasshi 2016 Apr;105(4):653-7

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April 2016
7 Reads

Sanguineous Pericardial Effusion and Cardiac Tamponade in the Setting of Graves' Disease: Report of a Case and Review of Previously Reported Cases.

Case Rep Med 2016 29;2016:9653412. Epub 2016 Jun 29.

Department of Internal Medicine, The University of New Mexico, Albuquerque, NM 87106, USA.

Introduction. Pericardial effusion in the setting of hyperthyroidism is rare. We present a patient with Graves' disease who developed a sanguineous pericardial effusion and cardiac tamponade. Read More

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http://dx.doi.org/10.1155/2016/9653412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942679PMC
July 2016
16 Reads

Thyrotoxic crisis presenting with jaundice.

BMC Res Notes 2016 Jun 23;9:320. Epub 2016 Jun 23.

Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.

Background: Thyrotoxic crisis is a medical emergency requiring early diagnosis and urgent management, which can be challenging due to its diverse clinical presentations. While common presentations include fever, sweating, palpitations, tremors and confusion, presence of jaundice is rare.

Case Presentation: We report a 35-year-old male who presented with jaundice due to cholestasis along with other features of thyrotoxic crisis due to Graves' disease. Read More

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http://dx.doi.org/10.1186/s13104-016-2126-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917949PMC
June 2016
10 Reads

A rare case of thyroid storm.

BMJ Case Rep 2016 Apr 18;2016:10.1136/bcr-2016-214603. Epub 2016 Apr 18.

Department of Family Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Thyroid storm is a rare and life-threatening state of thyroid hormone excess. Rapid recognition of thyroid storm is key to decreasing the morbidity and mortality of this condition. Clinical manifestations of thyroid storm include unexplained weight loss, hyperactivity and irritability. Read More

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http://dx.doi.org/10.1136/bcr-2016-214603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840694PMC
April 2016
7 Reads

Hyperthyroidism.

Lancet 2016 Aug 30;388(10047):906-918. Epub 2016 Mar 30.

Endocrine Unit, Fondazione IRCCS Cà Granda, Milan, Italy (S De Leo MD); Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy (S De Leo); and Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA (S De Leo, S Y Lee MD, Prof L E Braverman MD).

Hyperthyroidism is characterised by increased thyroid hormone synthesis and secretion from the thyroid gland, whereas thyrotoxicosis refers to the clinical syndrome of excess circulating thyroid hormones, irrespective of the source. The most common cause of hyperthyroidism is Graves' disease, followed by toxic nodular goitre. Other important causes of thyrotoxicosis include thyroiditis, iodine-induced and drug-induced thyroid dysfunction, and factitious ingestion of excess thyroid hormones. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01406736160027
Publisher Site
http://dx.doi.org/10.1016/S0140-6736(16)00278-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014602PMC
August 2016
77 Reads
29 Citations
45.220 Impact Factor

Onset of ulcerative colitis after thyrotoxicosis: a case report and review of the literature.

Eur Rev Med Pharmacol Sci 2016 ;20(4):685-8

Department of Internal Medicine, Gastroenterology and Liver Disease, Catholic University of the Sacred Heart of Rome, Rome, Italy.

Objective: Ulcerative colitis is a chronic disease that could be triggered by acute stressful events, such as gastrointestinal infections or emotional stress.

Patients And Methods: We reported the case of the onset of an ulcerative colitis after a thyrotoxicosis crisis and reviewed the literature about the relationships between thyroid dysfunctions and ulcerative colitis.

Results: A 38-year-old woman was diagnosed with ulcerative colitis after her third thyrotoxicosis crisis, two years after the diagnosis of Graves' disease. Read More

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October 2016
10 Reads

Impact of thyroidectomy on cardiac manifestations of Graves' disease.

Laryngoscope 2016 05 1;126(5):1256-9. Epub 2016 Mar 1.

Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.

Objectives/hypothesis: Graves' disease (GD) has multiple adverse effects on the cardiovascular system. We aimed to examine the outcome of thyroidectomy in patients with cardiac manifestations of GD and evaluate their associated postoperative complications.

Study Design: Retrospective analysis using a prospectively collected database. Read More

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http://dx.doi.org/10.1002/lary.25687DOI Listing
May 2016
8 Reads

Sudden cardiac arrest as a presentation of Brugada syndrome unmasked by thyroid storm.

BMJ Case Rep 2015 Dec 30;2015. Epub 2015 Dec 30.

Department of Intensive Care, Gelderse Vallei Hospital, Ede, The Netherlands.

An 18-year-old man suffered a sudden cardiac arrest with ventricular fibrillation and was successfully resuscitated. He had neither a medical nor family history of cardiac disease/sudden death, but was known to have Graves' disease, for which he was treated with radioactive iodine. Recently, block-and-replacement therapy had been discontinued to evaluate thyroid functioning. Read More

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http://casereports.bmj.com/content/2015/bcr-2015-212351.full
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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2015-21235
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http://dx.doi.org/10.1136/bcr-2015-212351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716267PMC
December 2015
19 Reads

Thyroid storm in a patient with Wolff-Parkinson-White syndrome.

BMJ Case Rep 2015 Dec 15;2015. Epub 2015 Dec 15.

Department of Endocrinology, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

A 44-year-old woman with no medical history presented to the emergency department with a 2 h history of sudden onset chest pressure, palpitations, diaphoresis and shortness of breath. She reported a 90-pound unintentional weight loss, increased appetite, irritability, night sweats and palpitations for 2 months. Physical examination revealed a heart rate (HR) of 269 bpm and a blood pressure of 116/94 mm Hg. Read More

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http://casereports.bmj.com/content/2015/bcr-2015-212569.full
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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2015-21256
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http://dx.doi.org/10.1136/bcr-2015-212569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680325PMC
December 2015
10 Reads

Simultaneous occurrence of diabetic ketoacidosis, thyroid storm, and multiple cerebral infarctions due to Moyamoya disease.

J Pediatr Endocrinol Metab 2016 Feb;29(2):221-5

Diabetic ketoacidosis (DKA) is one of the precipitating factors that can evoke a thyroid storm. Thyroid storm may cause cerebral ischemia in Moyamoya disease, which can coexist in patients with Graves' disease. A 16-year-old girl complaining of dizziness and palpitations visited the emergency department and was diagnosed with DKA combined with hyperthyroidism. Read More

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http://dx.doi.org/10.1515/jpem-2015-0204DOI Listing
February 2016
9 Reads

Hyperthyroidism in children.

Pediatr Rev 2015 Jun;36(6):239-48

Pediatric Endocrine Unit, Massachusetts General Hospital for Children and Harvard Medical School, Boston, MA.

On the basis of strong research evidence, hyperthyroidism is a rare but potentially serious disorder in childhood that, if uncontrolled, can lead to a wide range of complications, including effects on growth and development. • On the basis of strong research evidence, Graves' disease is the most common cause of hyperthyroidism in children, accounting for greater than 95% of cases. It is caused by stimulating antibodies to the thyroid-stimulating hormone receptor. Read More

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http://pedsinreview.aappublications.org/cgi/doi/10.1542/pir.
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http://dx.doi.org/10.1542/pir.36-6-239DOI Listing
June 2015
23 Reads

Thyroid diseases during pregnancy: a number of important issues.

Hormones (Athens) 2015 Jan-Mar;14(1):59-69

Department of Endocrinology, St. Paul Hospital, Thessaloniki, Greece.

The most common thyroid diseases during pregnancy are hyper- and hypothyroidism and their variants including isolated hypothyroxinemia (hypo-T4), autoimmune thyroid disease (AITD) and different types of goiter. AITD represents the main cause of hypothyroidism during pregnancy ranging in prevalence between 5 and 20% with an average of 7.8%. Read More

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http://www.hormones.gr/pdf/Hormones_2015_59.pdf
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January 2016
5 Reads

Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease.

Intern Med 2015 1;54(7):813-8. Epub 2015 Apr 1.

Department of Medicine, Diabetes, Metabolism and Endocrinology, Matsuyama Red Cross Hospital, Japan.

We herein describe a case of hypercalcemic crisis in a 52-year-old Japanese woman. She suffered from thirst and fatigue for one month. Her serum calcium (a) levels were 19. Read More

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http://dx.doi.org/10.2169/internalmedicine.54.2605DOI Listing
September 2015
8 Reads

Neonatal thyroid storm accompanied with severe anaemia.

J Pediatr Endocrinol Metab 2015 Jul;28(7-8):773-6

Neonatal thyroid storm is rare; the diagnostic criteria and management of neonatal thyroid storm have not been well established. In this paper, we report a preterm infant diagnosed with neonatal hyperthyroidism secondary to maternal Graves' disease who was discharged after therapy. Unfortunately, he was rehospitalised for neonatal thyroid storm. Read More

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http://dx.doi.org/10.1515/jpem-2014-0171DOI Listing
July 2015
10 Reads

A 46-Year-Old Woman With Dyspnea From an Inhalational Exposure, Triggering Thyroid Storm and Subsequent Multi-Organ System Failure.

J Intensive Care Med 2015 Dec 12;30(8):518-20. Epub 2015 Feb 12.

UMass Memorial Medical Center, Department of Pulmonary, Allergy and Critical Care, Worcester, MA, USA.

Background: Thyroid storm is a rare, life-threatening condition which arises in patients with thyrotoxicosis, with an annual incidence of 2 patients per 1,000,000 and a mortality rate of 11%.

Case: We present the case of a 46-year-old-female with a medical history of controlled mild intermittent asthma, who presented with a severe asthma exacerbation, that triggered thyroid storm after exposure to polyurethane fumes.

Conclusion: This patient represents, to the best of our knowledge, the first patient in whom the stress related to a severe asthma attack triggered the development of thyroid storm. Read More

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http://journals.sagepub.com/doi/10.1177/0885066615571527
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http://dx.doi.org/10.1177/0885066615571527DOI Listing
December 2015
10 Reads