Search our Database of Scientific Publications and Authors

I’m looking for a

    250 results match your criteria Hyperthyroidism Thyroid Storm & Graves Disease

    1 OF 5

    Hyperthyroidism-associated hypercalcemic crisis: A case report and review of the literature.
    Medicine (Baltimore) 2017 Jan;96(4):e6017
    Department of Endocrinology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
    Rationale: Hyperthyroidism is one of the major clinical causes of hypercalcaemia, however, hyperthyroidism-related hypercalcemic crisis is rare, only 1 case have been reported. The potential mechanisms are still not too clear. It may be related that thyroid hormone stimulate bone turnover, elevate serum calcium, increase urinary and fecal calcium excretion. Read More

    Thyroid Storm Precipitated by Diabetic Ketoacidosis and Influenza A: A Case Report and Literature Review.
    Intern Med 2017 15;56(2):181-185. Epub 2017 Jan 15.
    Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center, Japan.
    A 46-year-old woman with a history of Graves' disease presented with the chief complaints of appetite loss, weight loss, fatigue, nausea, and sweating. She was diagnosed with diabetic ketoacidosis (DKA), thyroid storm, and influenza A. She was treated with an intravenous insulin drip, intravenous fluid therapy, intravenous hydrocortisone, oral potassium iodine, and oral methimazole. Read More

    Association of KCNJ2 Genetic Variants with Susceptibility to Thyrotoxic Periodic Paralysis in Patients with Graves' Disease.
    Exp Clin Endocrinol Diabetes 2017 Feb 22;125(2):75-78. Epub 2016 Dec 22.
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
    Objective: Thyrotoxic periodic paralysis (TPP) is characterized by acute onset paralysis and hypokalemia predominantly in male patients with thyrotoxicosis. Recent studies have emphasized the importance of potassium channels, which might explain the underlying mechanism of TPP. The KCNJ2 gene encodes the inward-rectifying potassium channel. Read More

    A case of hypercalcaemic crisis secondary to coexistence of primary hyperparathyroidism and Graves' disease.
    Endocr Regul 2016 Oct;50(4):225-228
    A 46 year-old female patient presented to the hospital with ongoing and progressively increasing fatigue, severe nausea and vomiting, loss of appetite, constipation, palpitations and somnolence. Laboratory evaluation revealed a severe hypercalcaemia and overt hyperthyroidism. She was diagnosed with primary hyperparathyroidism accompanied by Graves' disease. Read More

    A Case of Thyroid Storm Associated with Cardiomyopathy and Poststreptococcal Glomerulonephritis.
    Case Rep Pediatr 2016 27;2016:7192359. Epub 2016 Oct 27.
    Department of Pediatric Endocrinology and Diabetes and Department of Pediatric Nephrology, The Children's Hospital at Montefiore, 3415 Bainbridge Ave., Bronx, NY 10467, USA.
    Thyroid storm has a high mortality rate and is often associated with a precipitating factor such as intercurrent illness or infection. It is rare in pediatric patients. Cardiac disease in hyperthyroidism mostly manifests itself as tachycardia but more serious cardiac findings have also been described. Read More

    Low cardiac output thyroid storm in a girl with Graves' disease.
    Pediatr Int 2016 Oct;58(10):1080-1083
    Division of Endocrinology and Metabolism, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    A 15-year-old girl with Graves' disease presented with hypotension after methimazole and propranolol were re-started for hyperthyroidism. She was found to have pulmonary artery hypertension resulting in obstructive shock. Thyroid storm was diagnosed according to Burch and Wartofsky score. Read More

    Antithyroid drugs during breastfeeding.
    Clin Endocrinol (Oxf) 2016 Dec 22;85(6):827-830. Epub 2016 Sep 22.
    Department of Nutrition-Related Disease Prevention, School of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland.
    Antithyroid drugs (ATDs) are widely used for the treatment of Graves' disease (GD) in the general population. Over the past decade, there has been an increasing awareness that several disturbances of thyroid function may occur in mothers after delivery which may be more prevalent than previously appreciated. Exacerbation of immune reactions occurs 3-12 month following delivery. Read More

    Sanguineous Pericardial Effusion and Cardiac Tamponade in the Setting of Graves' Disease: Report of a Case and Review of Previously Reported Cases.
    Case Rep Med 2016 29;2016:9653412. Epub 2016 Jun 29.
    Department of Internal Medicine, The University of New Mexico, Albuquerque, NM 87106, USA.
    Introduction. Pericardial effusion in the setting of hyperthyroidism is rare. We present a patient with Graves' disease who developed a sanguineous pericardial effusion and cardiac tamponade. Read More

    Thyrotoxic crisis presenting with jaundice.
    BMC Res Notes 2016 Jun 23;9:320. Epub 2016 Jun 23.
    Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
    Background: Thyrotoxic crisis is a medical emergency requiring early diagnosis and urgent management, which can be challenging due to its diverse clinical presentations. While common presentations include fever, sweating, palpitations, tremors and confusion, presence of jaundice is rare.

    Case Presentation: We report a 35-year-old male who presented with jaundice due to cholestasis along with other features of thyrotoxic crisis due to Graves' disease. Read More

    A rare case of thyroid storm.
    BMJ Case Rep 2016 Apr 18;2016:10.1136/bcr-2016-214603. Epub 2016 Apr 18.
    Department of Family Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
    Thyroid storm is a rare and life-threatening state of thyroid hormone excess. Rapid recognition of thyroid storm is key to decreasing the morbidity and mortality of this condition. Clinical manifestations of thyroid storm include unexplained weight loss, hyperactivity and irritability. Read More

    Lancet 2016 Aug 30;388(10047):906-18. Epub 2016 Mar 30.
    Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA. Electronic address:
    Hyperthyroidism is characterised by increased thyroid hormone synthesis and secretion from the thyroid gland, whereas thyrotoxicosis refers to the clinical syndrome of excess circulating thyroid hormones, irrespective of the source. The most common cause of hyperthyroidism is Graves' disease, followed by toxic nodular goitre. Other important causes of thyrotoxicosis include thyroiditis, iodine-induced and drug-induced thyroid dysfunction, and factitious ingestion of excess thyroid hormones. Read More

    Onset of ulcerative colitis after thyrotoxicosis: a case report and review of the literature.
    Eur Rev Med Pharmacol Sci 2016 ;20(4):685-8
    Department of Internal Medicine, Gastroenterology and Liver Disease, Catholic University of the Sacred Heart of Rome, Rome, Italy.
    Objective: Ulcerative colitis is a chronic disease that could be triggered by acute stressful events, such as gastrointestinal infections or emotional stress.

    Patients And Methods: We reported the case of the onset of an ulcerative colitis after a thyrotoxicosis crisis and reviewed the literature about the relationships between thyroid dysfunctions and ulcerative colitis.

    Results: A 38-year-old woman was diagnosed with ulcerative colitis after her third thyrotoxicosis crisis, two years after the diagnosis of Graves' disease. Read More

    Impact of thyroidectomy on cardiac manifestations of Graves' disease.
    Laryngoscope 2016 May 1;126(5):1256-9. Epub 2016 Mar 1.
    Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.
    Objectives/hypothesis: Graves' disease (GD) has multiple adverse effects on the cardiovascular system. We aimed to examine the outcome of thyroidectomy in patients with cardiac manifestations of GD and evaluate their associated postoperative complications.

    Study Design: Retrospective analysis using a prospectively collected database. Read More

    Sudden cardiac arrest as a presentation of Brugada syndrome unmasked by thyroid storm.
    BMJ Case Rep 2015 Dec 30;2015. Epub 2015 Dec 30.
    Department of Intensive Care, Gelderse Vallei Hospital, Ede, The Netherlands.
    An 18-year-old man suffered a sudden cardiac arrest with ventricular fibrillation and was successfully resuscitated. He had neither a medical nor family history of cardiac disease/sudden death, but was known to have Graves' disease, for which he was treated with radioactive iodine. Recently, block-and-replacement therapy had been discontinued to evaluate thyroid functioning. Read More

    Thyroid storm in a patient with Wolff-Parkinson-White syndrome.
    BMJ Case Rep 2015 Dec 15;2015. Epub 2015 Dec 15.
    Department of Endocrinology, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
    A 44-year-old woman with no medical history presented to the emergency department with a 2 h history of sudden onset chest pressure, palpitations, diaphoresis and shortness of breath. She reported a 90-pound unintentional weight loss, increased appetite, irritability, night sweats and palpitations for 2 months. Physical examination revealed a heart rate (HR) of 269 bpm and a blood pressure of 116/94 mm Hg. Read More

    Simultaneous occurrence of diabetic ketoacidosis, thyroid storm, and multiple cerebral infarctions due to Moyamoya disease.
    J Pediatr Endocrinol Metab 2016 Feb;29(2):221-5
    Diabetic ketoacidosis (DKA) is one of the precipitating factors that can evoke a thyroid storm. Thyroid storm may cause cerebral ischemia in Moyamoya disease, which can coexist in patients with Graves' disease. A 16-year-old girl complaining of dizziness and palpitations visited the emergency department and was diagnosed with DKA combined with hyperthyroidism. Read More

    Hyperthyroidism in children.
    Pediatr Rev 2015 Jun;36(6):239-48
    Pediatric Endocrine Unit, Massachusetts General Hospital for Children and Harvard Medical School, Boston, MA.
    On the basis of strong research evidence, hyperthyroidism is a rare but potentially serious disorder in childhood that, if uncontrolled, can lead to a wide range of complications, including effects on growth and development. • On the basis of strong research evidence, Graves' disease is the most common cause of hyperthyroidism in children, accounting for greater than 95% of cases. It is caused by stimulating antibodies to the thyroid-stimulating hormone receptor. Read More

    Thyroid diseases during pregnancy: a number of important issues.
    Hormones (Athens) 2015 Jan-Mar;14(1):59-69
    Department of Endocrinology, St. Paul Hospital, Thessaloniki, Greece.
    The most common thyroid diseases during pregnancy are hyper- and hypothyroidism and their variants including isolated hypothyroxinemia (hypo-T4), autoimmune thyroid disease (AITD) and different types of goiter. AITD represents the main cause of hypothyroidism during pregnancy ranging in prevalence between 5 and 20% with an average of 7.8%. Read More

    Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease.
    Intern Med 2015 1;54(7):813-8. Epub 2015 Apr 1.
    Department of Medicine, Diabetes, Metabolism and Endocrinology, Matsuyama Red Cross Hospital, Japan.
    We herein describe a case of hypercalcemic crisis in a 52-year-old Japanese woman. She suffered from thirst and fatigue for one month. Her serum calcium (a) levels were 19. Read More

    Neonatal thyroid storm accompanied with severe anaemia.
    J Pediatr Endocrinol Metab 2015 Jul;28(7-8):773-6
    Neonatal thyroid storm is rare; the diagnostic criteria and management of neonatal thyroid storm have not been well established. In this paper, we report a preterm infant diagnosed with neonatal hyperthyroidism secondary to maternal Graves' disease who was discharged after therapy. Unfortunately, he was rehospitalised for neonatal thyroid storm. Read More

    A 46-Year-Old Woman With Dyspnea From an Inhalational Exposure, Triggering Thyroid Storm and Subsequent Multi-Organ System Failure.
    J Intensive Care Med 2015 Dec 12;30(8):518-20. Epub 2015 Feb 12.
    UMass Memorial Medical Center, Department of Pulmonary, Allergy and Critical Care, Worcester, MA, USA.
    Background: Thyroid storm is a rare, life-threatening condition which arises in patients with thyrotoxicosis, with an annual incidence of 2 patients per 1,000,000 and a mortality rate of 11%.

    Case: We present the case of a 46-year-old-female with a medical history of controlled mild intermittent asthma, who presented with a severe asthma exacerbation, that triggered thyroid storm after exposure to polyurethane fumes.

    Conclusion: This patient represents, to the best of our knowledge, the first patient in whom the stress related to a severe asthma attack triggered the development of thyroid storm. Read More

    Jod-Basedow effect due to prolonged use of lugol solution-case report.
    Rev Med Chir Soc Med Nat Iasi 2014 Oct-Dec;118(4):1013-7
    University of Medicine and Pharmacy Grigore T. Popa - Iaşi, Department of Medical Specialties (II).
    Graves' disease is the most common form of hyperthyroidism, accounting for 60-80% of all cases of thyrotoxicosis. If left untreated, it may lead to severe thyrotoxicosis with cardiovascular, ocular, psychiatric complication, and in extreme cases thyrotoxic crisis with a high mortality rate. We present the case of a 50-years-old woman diagnosed in another service with Graves' disease and treated for many years with antithyroid drugs (ATDs), admitted to our service for a relapse due to treatment discontinuation. Read More

    [Prolonged psychosis associated with thyrotoxicosis during the subacute stage of cardioembolic stroke in a patient with untreated basedow disease].
    Brain Nerve 2014 Dec;66(12):1509-14
    Department of Neurology, Fukuoka University Faculty of Medicine.
    A 57-year-old female developed dizziness and forgetfulness several days before admission. She was admitted to our hospital because of a headache and nausea. On admission, she had a mild disturbance of consciousness and right hemiparesis. Read More

    Hashimoto's encephalopathy: report of three cases.
    J Formos Med Assoc 2014 Nov 3;113(11):862-6. Epub 2012 Mar 3.
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:
    Both severe thyrotoxicosis and hypothyroidism may affect brain function and cause a change in consciousness, as seen with a thyroid storm or myxedema coma. However, encephalopathy may also develop in patients with autoimmune thyroid diseases independent of actual thyroid function level, and this is known as Hashimoto's encephalopathy. Although most patients are found to have Hashimoto's thyroiditis, less frequently they have Graves' disease. Read More

    Review of oral cholecystographic agents for the management of hyperthyroidism.
    Endocr Pract 2014 Oct;20(10):1084-92
    Department of Medicine, University of California, Los Angeles, Los Angeles, California.
    Objective: Although the use of oral cholecystographic agents (OCAs) had declined due to limited availability, there is literature to suggest it is an effective medication for thyrotoxicosis in appropriate clinical situations.

    Methods: The authors performed a PubMed search and systematically reviewed all the English written case reports, original studies and reviews from 1953 to 2012. Additional information was supplemented from available online pharmacologic databases. Read More

    L-carnitine treatment in a seriously ill cancer patient with severe hyperthyroidism.
    Hormones (Athens) 2014 Jul-Sep;13(3):407-12
    Section of Endocrinology, Department of Clinical & Experimental Medicine, University of Messina, Messina, Interdepartmental Program of Molecular & Clinical Endocrinology and Women's Endocrine Health, A.O.U. Policlinico G. Martino, Italy.
    Objective: To report a case of vaccine-induced Graves' disease successfully managed with L-carnitine and propranolol and without antithyroid drugs (ATDs). ATDs sometimes need to be used at low doses or can be contraindicated/refused. One of the ancillary compounds available is L-carnitine. Read More

    [Oedema and haemorrhagic diathesis in a 50-year-old woman with thyrotoxicosis].
    Internist (Berl) 2014 Nov;55(11):1352-5
    Abteilung für Innere Medizin, St. Josef-Hospital Troisdorf, Hospitalstr. 45, 53840, Troisdorf, Deutschland,
    We describe the case of a 50-year-old woman who presented with tachyarrhythmia, mild fever, peripheral oedema, ascites, epistaxis and gastrointestinal haemorrhage. Blood analysis revealed hyperthyroxinaemia. Analysis of thyroid-stimulating antibodies highlighted Graves' disease being the cause of the prevailing thyrotoxic crisis. Read More

    Sudden unexpected death in the setting of undiagnosed Graves' disease.
    Forensic Sci Med Pathol 2014 Sep 1;10(3):452-6. Epub 2014 Jun 1.
    Department of Forensic Medicine, Victorian Institute of Forensic Medicine, Monash University, 57-83 Kavanagh Street, Southbank, VIC, 3006, Australia,
    Graves' disease is the most common cause of hyperthyroidism and is classically characterized by the clinical triad of diffuse toxic goiter, infiltrative ophthalmopathy with exophthalmos and an infiltrative dermopathy. While the name of the Irishman Robert Graves has received the eponymous honor, the first description of the condition in the English language can be attributed to the Englishman Caleb Perry, while in continental Europe the entity in name once honored Karl von Basedow. We present the case of a previously well 43 year old woman who presented in supraventricular tachycardia and acute pulmonary edema and died despite treatment and without a diagnosis for cause of death. Read More

    Thyroid storm following radioactive iodine (RAI) therapy for pediatric graves disease.
    Am J Case Rep 2014 14;15:212-5. Epub 2014 May 14.
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, U.S.A.
    Patient: Female, 11 FINAL DIAGNOSIS: Thyroid storm Symptoms: Diarrhea • tachycardia • tachypnea • tremor • wheezing

    Medication: - Clinical Procedure: - Specialty: -

    Objective: Rare disease.

    Background: A growing number of pediatric endocrinologists treat Graves disease with radioactive iodine (RAI) therapy due to the typically definitive nature of I-131 therapy. Given the published benefits and perceived low risks of RAI when compared to surgery or long-term anti-thyroid medication, the trend towards therapy with RAI is likely to continue. Read More

    Hyperthyroidism and thyrotoxicosis.
    Emerg Med Clin North Am 2014 May 15;32(2):277-92. Epub 2014 Mar 15.
    Department of Emergency Medicine, University of Maryland Medical System, University of Maryland, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA.
    Hyperthyroidism and thyrotoxicosis are hypermetabolic conditions that cause significant morbidity and mortality. The diagnosis can be difficult because symptoms can mimic many other disease states leading to inaccurate or untimely diagnoses and management. Thyroid storm is the most severe form of thyrotoxicosis, hallmarked by altered sensorium, and, if untreated, is associated with significant mortality. Read More

    A case of thyroid storm with a markedly elevated level of circulating soluble interleukin-2 receptor complicated by multiple organ failure and disseminated intravascular coagulation syndrome.
    Endocr J 2014 20;61(7):691-6. Epub 2014 May 20.
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
    Thyroid storm (TS) is a life-threatening endocrine emergency. However, the pathogenesis of TS is poorly understood. A 40-year-old man was admitted to a nearby hospital with body weight loss and jaundice. Read More

    Glucose variability before and after treatment of a patient with Graves' disease complicated by diabetes mellitus: assessment by continuous glucose monitoring.
    Endocr J 2014 11;61(4):321-8. Epub 2014 Jan 11.
    First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushyu 807-8555, Japan.
    A 48-year-old woman was diagnosed and treated for Graves' disease (GD) in 1999 but she discontinued treatment at her own discretion. In 2011, she was admitted to a local hospital for management of thyrotoxic crisis. Treatment with propylthiouracil, iodide potassium (KI), and prednisolone (PSL) was started, which resulted in improvement of the general condition. Read More

    Thyroid disease and the nervous system.
    Handb Clin Neurol 2014 ;120:703-35
    Sheffield Institute for Translational Neuroscience, University of Sheffield and Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK. Electronic address:
    Thyroid disorders are common in the general population and in hospitalized patients. Thyroid disease may present first with neurological complications or else may occur concurrently in patients suffering other neurological disorders, particularly those with an autoimmune etiology. For this reason neurologists will commonly encounter patients with thyroid disease. Read More

    [Thyrotoxic hypokalemic periodic paralysis. A case report].
    Semergen 2013 Nov-Dec;39(8):e68-70. Epub 2012 Nov 2.
    Servicio de Medicina Interna, Hospital de Antequera, Málaga, España.
    Thyrotoxic hypokalemic periodic paralysis is an uncommon complication of thyrotoxicosis, characterized by attacks of generalized muscular weakness associated with hypokalemia in patients with hyperthyroidism, most frequently with Graves-Basedow disease. Treatment with antithyroid drugs and potassium supplements reversed the symptoms and the episodes of acute muscular weakness did not reappear. Read More

    Thyroidectomy in a patient with thyroid storm: report of a case.
    Surg Today 2015 Jan 17;45(1):110-4. Epub 2013 Oct 17.
    Department of Surgery, Tottori Prefectural Kousei Hospital, 150 Higashisyouwa-machi, Kurayoshi, Tottori, 682-0804, Japan,
    Thyroid storm is a life-threatening condition that is generally considered to be a contradiction to surgical intervention. We herein describe the case of a 37-year-old patient with a history of Graves' disease who was transferred to Tottori University Hospital with thyroid storm. She had been followed by her family doctor since 2006, but she had stopped taking her medication of her own volition in 2010. Read More

    Total thyroidectomy for Graves' disease: compliance with American Thyroid Association guidelines may not always be necessary.
    Surgery 2013 Nov 26;154(5):1009-15. Epub 2013 Sep 26.
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Nashville, TN. Electronic address:
    Background: Total thyroidectomy (TT) is the preferred operative approach to Graves' disease. Current guidelines of the American Thyroid Association call for the administration of potassium iodide (KI) and achievement of euthyroid state before operation. Small numbers and a mixture of operative approaches spanning several decades hinder previous operative series. Read More

    Thyroid storm and arrhythmic storm: a potentially fatal combination.
    Am J Emerg Med 2013 Sep 23;31(9):1418.e3-5. Epub 2013 May 23.
    Cardiology Department, Hospital Santo António - Centro Hospitalar do Porto, Porto, Portugal. Electronic address:
    Thyroid storm is a rare clinical emergency with a mortality rate between 20% and 30%. Cardiac arrhythmias associated with thyrotoxicosis are usually supraventricular. Ventricular arrhythmias are rarely associated with this entity and tend to occur in patients with intrinsic cardiac disease. Read More

    A patient who experienced thyroid storm complicated by rhabdomyolysis, deep vein thrombosis, and a silent pulmonary embolism: a case report.
    BMC Res Notes 2013 May 20;6:198. Epub 2013 May 20.
    Background: Thyroid storm is a serious condition of thyrotoxicosis. Hyperthyroidism often presents with thrombotic events, especially at cerebral sites; however, the possible association between a lower extremity deep vein thrombosis (LEDVT) and thyroid storm has not been previously reported. We encountered a patient who developed thyroid storm, associated with rhabdomyolysis, followed by LEDVT and a small silent pulmonary embolism (PE). Read More

    Takotsubo cardiomyopathy associated with thyrotoxicosis: a case report and review of the literature.
    Thyroid 2014 Feb 25;24(2):383-9. Epub 2013 Jul 25.
    1 Department of Internal Medicine, Medstar Washington Hospital Center , Washington, District of Columbia.
    Background: Takotsubo or stress-induced cardiomyopathy is a form of reversible cardiomyopathy commonly associated with emotional or physical stress. Thyrotoxicosis has been identified as a rare cause of Takotsubo cardiomyopathy, with only 12 cases reported in the literature. Here, we report a case of thyroid storm presenting with Takotsubo cardiomyopathy in the setting of Graves' disease. Read More

    [Diagnosis and treatment of thyroid storm].
    Nihon Rinsho 2012 Nov;70(11):2000-4
    First Department of Medicine, Wakayama Medical University.
    Thyrotoxic storm is a life-threatening condition requiring emergency treatment. Neither its epidemiological data nor diagnostic criteria have been fully established. We clarified the clinical and epidemiological characteristics of thyroid storm using nationwide surveys and then formulate diagnostic criteria for thyroid storm. Read More

    [Guidelines for the diagnosis and management of thyroid disease and their utility].
    Nihon Rinsho 2012 Nov;70(11):1857-64
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine.
    Thyroid dysfunction is a common disorder in daily clinical practice, however due to unspecific and diverse symptoms of the disease, it is sometimes hard to make a definite diagnosis. Japan thyroid association (JTA) published 'Guideline for the diagnosis of thyroid disease, 2010' and it is open to the public on the JTA website(http : //www.japanthyroid. Read More

    Thyroid storm masked by hemodialysis and glucocorticoid therapy in a patient with rheumatoid arthritis.
    Case Rep Nephrol Urol 2012 Jan 16;2(1):6-10. Epub 2012 Feb 16.
    Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.
    Thyroid function test values are generally at low levels in patients with end-stage kidney disease. Life-threatening thyrotoxicosis or thyroid storm is rare, especially in hemodialysis (HD) patients, and is characterized by multisystem involvement and a high mortality rate if not immediately recognized and treated. Here, we report a female patient with severe symptomatic thyroid storm, receiving long-term HD and glucocorticoid therapy. Read More

    Surviving the storm: two cases of thyroid storm successfully treated with plasmapheresis.
    BMJ Case Rep 2012 Oct 19;2012. Epub 2012 Oct 19.
    Department of Medicine/Endocrinology, Baylor College of Medicine, Houston, Texas, USA.
    Thyroid storm is a rare, but critical, illness that can lead to multiorgan failure and carries a high death rate. The following case series describes two adult men with Graves' disease who presented in thyroid storm and either failed or could not tolerate conventional medical management. However, both patients responded well to plasmapheresis, which resulted in clinical and biochemical stabilisation of their disease processes. Read More

    Significant attenuation of stimulated cortisol in early Graves disease without adrenal autoimmunity.
    Endocr Pract 2012 Nov-Dec;18(6):924-30
    Section of Diabetes and Endocrinology, Caerphilly Miners' Hospital, Caerphilly, UK.
    Objective: To investigate cortisol responses to adrenocorticotropic hormone during thyrotoxic (G1) and euthyroid (G2) phases in patients with Graves disease (GD) who were without adrenal autoimmunity.

    Methods: Fifteen patients with GD, who were thyrotropin receptor antibody positive and 21-hydroxylase antibody negative, were recruited to this prospective pilot study. A modified short Synacthen test (SST) was performed, in which cortisol was measured every 30 minutes for 2 hours during G1 and G2. Read More

    Cholestatic hepatic injury due to a thyroid storm: a case report from a resource limited setting.
    Thyroid Res 2012 Jul 28;5(1). Epub 2012 Jul 28.
    Department of Medicine, Makerere University College of Health Sciences and Emergency Medicine unit, Mulago national referral and teaching hospital, Kampala, Uganda.
    Introduction: Thyroid storm is an endocrinological emergency caused by an exacerbation of the hyperthyroid state and is characterized by multi organ dysfunction. Liver dysfunction or injury predominantly of a cholestatic type is one of the atypical manifestations of thyroid storm and has been previously described in literature. However, there have been few published case reports among African patients and from resource limited settings. Read More

    1 OF 5