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    262 results match your criteria Hyperthyroidism Thyroid Storm & Graves Disease

    1 OF 6

    Type 2 Diabetes Decompensation as the Clinical Presentation of Thyroid Storm - Cause or Consequence?
    Eur Endocrinol 2017 Aug 22;13(2):99-101. Epub 2017 Aug 22.
    Endocrinology Department, Hospital de Braga, Braga, Portugal.
    This case study aims to discuss the unusual forms of hyperthyroidism presentation, the nonspecific symptoms and precipitating events. A 70-year-old male was taken to the emergency department for hyperglycaemia, nausea, vomiting and altered mental status with a week of evolution. He had a past medical history of type 2 diabetes, hypertension and dyslipidemia. Read More

    Thyrotoxic crisis as an acute clinical presentation in a child.
    BMJ Case Rep 2018 Mar 23;2018. Epub 2018 Mar 23.
    Paediatrics, University Hospitals of Leicester Foundation Trust, Leicester, UK.
    A previously well, 4-year-old girl presented with a 4-6 weeks' history of increased appetite, weight loss, tiredness, sleep difficulty, excessive sweating, swelling in the neck and new-onset 'prominent, protruding eyes.' Family history revealed paternal grandmother receiving treatment for hyperthyroidism. Clinical assessment demonstrated features of thyrotoxicosis (tachycardia, warm peripheries, small smooth goitre with no nodules, exophthalmos). Read More

    Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm.
    Intern Med 2018 Feb 28. Epub 2018 Feb 28.
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan.
    We herein report a case of central diabetes insipidus complicated with thyroid storm. A middle-aged woman who was receiving treatment for Graves' disease suddenly complained of polydipsia, polyuria and general fatigue. Laboratory tests showed hyperthyroidism, hypernatremia, hypoosmolar urine and a decreased plasma vasopressin level. Read More

    Cytomegalovirus-mononucleosis-induced thyroiditis in an immunocompetent patient.
    Endocrinol Diabetes Metab Case Rep 2017 24;2017. Epub 2017 Nov 24.
    Division of Endocrinology, Jewish General Hospital, Montréal, Québec, Canada.
    Enteroviruses, including coxsackieviruses and Echovirus, are well known pathogens responsible for the development of thyroiditis. We describe the case of a 49-year-old woman with no personal or family history of thyroid disease who presented to the emergency room with a two-week history of daily fevers up to 39°C, a sore throat, occasional palpitations and diaphoresis, decreased appetite and an unintentional 10 kg weight loss over the same time course Physical examination revealed mild tachycardia, an intention tremor and a normal-sized, nontender thyroid gland without palpable nodules. The remainder of the physical examination was unremarkable and without stigmata of Graves' disease. Read More

    Preoperative management in patients with Graves' disease.
    Gland Surg 2017 Oct;6(5):476-481
    Department of Medicine and Surgery, University of Insubria, Varese, Italy.
    Graves' disease is the most frequent cause of hyperthyroidism in iodine-sufficient geographical areas and is characterized by the presence in patients' serum of autoantibodies directed against the thyrotropin receptor (TRAb) that cause overproduction and release of thyroid hormones. Clinical presentation results from both hyperthyroidism and underlying autoimmunity. The diagnosis is based on characteristic clinical features and biochemical abnormalities. Read More

    Total Thyroidectomy for Thyroid Cancer Followed by Thyroid Storm due to Thyrotropin Receptor Antibody Stimulation of Metastatic Thyroid Tissue.
    Eur Thyroid J 2017 Sep 3;6(5):276-280. Epub 2017 Aug 3.
    Department of Endocrinology, Odense University Hospital, Odense, Denmark.
    Background: Graves disease (GD) is an autoimmune condition characterized by the presence of antibodies against the thyrotropin receptor (TRAB), which stimulate the thyroid gland to produce excess thyroid hormone. Theoretically, TRAB could stimulate highly differentiated thyroid cancer tissue and/or metastases to produce thyroid hormone.

    Case: A 68-year-old male, with weight loss and palpitations, was diagnosed with thyrotoxicosis. Read More

    Malignant Hyperthermia Versus Thyroid Storm in a Patient With Symptomatic Graves Disease: A Case Report.
    A A Pract 2018 Mar;10(5):97-99
    From the Department of Anesthesiology, Loyola University Medical Center, Maywood, Illinois.
    Malignant hyperthermia and thyroid storm are intraoperative emergencies with overlapping symptoms but different treatment protocols. We faced this diagnostic dilemma in a 25-year-old patient with symptomatic hyperthyroidism, elevated free T3 and free T4, and low thyroid-stimulating hormone from Graves disease despite treatment with propranolol 80 mg daily and methimazole 40 mg every 8 hours. During thyroidectomy, he developed hyperthermia and hypercarbia without tachycardia. Read More

    Thyroid storm and warm autoimmune hemolytic anemia.
    Transfus Apher Sci 2017 Aug 18;56(4):606-608. Epub 2017 Aug 18.
    Division of Hematology Oncology, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX, United States.
    Graves' disease is often associated with other autoimmune disorders, including rare associations with autoimmune hemolytic anemia (AIHA). We describe a unique presentation of thyroid storm and warm AIHA diagnosed concurrently in a young female with hyperthyroidism. The patient presented with nausea, vomiting, diarrhea and altered mental status. Read More

    Early Timing of Thyroidectomy for Hyperthyroidism in Graves' Disease Improves Biochemical Recovery.
    World J Surg 2017 10;41(10):2545-2550
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich and University of Zurich, Frauenklinikstrasse 24, 8091, Zurich, Switzerland.
    Background: The role of thyroidectomy as an early treatment for hyperthyroidism has been poorly investigated. Our aim was to examine its success rates, particularly focusing on thyroidectomy as an early treatment.

    Methods: Patients with thyroidectomy for hyperthyroidism between February 2008 and October 2014 were included. Read More

    Lugol's solution-induced painless thyroiditis.
    Endocrinol Diabetes Metab Case Rep 2017 30;2017. Epub 2017 May 30.
    Division of Endocrinology and Metabolism, Department of Medicine, McGill University Health Centre, Montreal, QuebecCanada.
    Lugol's solution is usually employed for a limited period for thyroidectomy preparation in patients with Graves' disease and for the control of severe thyrotoxicosis and thyroid storm. We describe a rare case of Lugol's solution-induced painless thyroiditis. In November 2014, a 59-year-old woman was prescribed Lugol's solution four drops per day for the alleviation of menopausal symptoms. Read More

    Successful treatment of thyroid storm presenting as recurrent cardiac arrest and subsequent multiorgan failure by continuous renal replacement therapy.
    Endocrinol Diabetes Metab Case Rep 2017 31;2017. Epub 2017 Mar 31.
    Division of Nephrology, Kosin University College of Medicine, BusanRepublic of Korea.
    Summary: Thyroid storm is a rare and potentially life-threatening medical emergency. We experienced a case of thyroid storm associated with sepsis caused by pneumonia, which had a catastrophic course including recurrent cardiac arrest and subsequent multiple organ failure (MOF). A 22-year-old female patient with a 10-year history of Graves' disease was transferred to our emergency department (ED). Read More

    Hyperthyroidism-associated hypercalcemic crisis: A case report and review of the literature.
    Medicine (Baltimore) 2017 Jan;96(4):e6017
    Department of Endocrinology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
    Rationale: Hyperthyroidism is one of the major clinical causes of hypercalcaemia, however, hyperthyroidism-related hypercalcemic crisis is rare, only 1 case have been reported. The potential mechanisms are still not too clear. It may be related that thyroid hormone stimulate bone turnover, elevate serum calcium, increase urinary and fecal calcium excretion. Read More

    Thyroid Storm Precipitated by Diabetic Ketoacidosis and Influenza A: A Case Report and Literature Review.
    Intern Med 2017 15;56(2):181-185. Epub 2017 Jan 15.
    Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center, Japan.
    A 46-year-old woman with a history of Graves' disease presented with the chief complaints of appetite loss, weight loss, fatigue, nausea, and sweating. She was diagnosed with diabetic ketoacidosis (DKA), thyroid storm, and influenza A. She was treated with an intravenous insulin drip, intravenous fluid therapy, intravenous hydrocortisone, oral potassium iodine, and oral methimazole. Read More

    Association of KCNJ2 Genetic Variants with Susceptibility to Thyrotoxic Periodic Paralysis in Patients with Graves' Disease.
    Exp Clin Endocrinol Diabetes 2017 Feb 22;125(2):75-78. Epub 2016 Dec 22.
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
    Thyrotoxic periodic paralysis (TPP) is characterized by acute onset paralysis and hypokalemia predominantly in male patients with thyrotoxicosis. Recent studies have emphasized the importance of potassium channels, which might explain the underlying mechanism of TPP. The gene encodes the inward-rectifying potassium channel. Read More

    A case of hypercalcaemic crisis secondary to coexistence of primary hyperparathyroidism and Graves' disease.
    Endocr Regul 2016 Oct;50(4):225-228
    A 46 year-old female patient presented to the hospital with ongoing and progressively increasing fatigue, severe nausea and vomiting, loss of appetite, constipation, palpitations and somnolence. Laboratory evaluation revealed a severe hypercalcaemia and overt hyperthyroidism. She was diagnosed with primary hyperparathyroidism accompanied by Graves' disease. Read More

    A Case of Thyroid Storm Associated with Cardiomyopathy and Poststreptococcal Glomerulonephritis.
    Case Rep Pediatr 2016 27;2016:7192359. Epub 2016 Oct 27.
    Department of Pediatric Endocrinology and Diabetes and Department of Pediatric Nephrology, The Children's Hospital at Montefiore, 3415 Bainbridge Ave., Bronx, NY 10467, USA.
    Thyroid storm has a high mortality rate and is often associated with a precipitating factor such as intercurrent illness or infection. It is rare in pediatric patients. Cardiac disease in hyperthyroidism mostly manifests itself as tachycardia but more serious cardiac findings have also been described. Read More

    Low cardiac output thyroid storm in a girl with Graves' disease.
    Pediatr Int 2016 Oct;58(10):1080-1083
    Division of Endocrinology and Metabolism, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    A 15-year-old girl with Graves' disease presented with hypotension after methimazole and propranolol were re-started for hyperthyroidism. She was found to have pulmonary artery hypertension resulting in obstructive shock. Thyroid storm was diagnosed according to Burch and Wartofsky score. Read More

    Antithyroid drugs during breastfeeding.
    Clin Endocrinol (Oxf) 2016 Dec 22;85(6):827-830. Epub 2016 Sep 22.
    Department of Nutrition-Related Disease Prevention, School of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland.
    Antithyroid drugs (ATDs) are widely used for the treatment of Graves' disease (GD) in the general population. Over the past decade, there has been an increasing awareness that several disturbances of thyroid function may occur in mothers after delivery which may be more prevalent than previously appreciated. Exacerbation of immune reactions occurs 3-12 month following delivery. Read More

    Sanguineous Pericardial Effusion and Cardiac Tamponade in the Setting of Graves' Disease: Report of a Case and Review of Previously Reported Cases.
    Case Rep Med 2016 29;2016:9653412. Epub 2016 Jun 29.
    Department of Internal Medicine, The University of New Mexico, Albuquerque, NM 87106, USA.
    Introduction. Pericardial effusion in the setting of hyperthyroidism is rare. We present a patient with Graves' disease who developed a sanguineous pericardial effusion and cardiac tamponade. Read More

    Thyrotoxic crisis presenting with jaundice.
    BMC Res Notes 2016 Jun 23;9:320. Epub 2016 Jun 23.
    Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
    Background: Thyrotoxic crisis is a medical emergency requiring early diagnosis and urgent management, which can be challenging due to its diverse clinical presentations. While common presentations include fever, sweating, palpitations, tremors and confusion, presence of jaundice is rare.

    Case Presentation: We report a 35-year-old male who presented with jaundice due to cholestasis along with other features of thyrotoxic crisis due to Graves' disease. Read More

    A rare case of thyroid storm.
    BMJ Case Rep 2016 Apr 18;2016:10.1136/bcr-2016-214603. Epub 2016 Apr 18.
    Department of Family Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
    Thyroid storm is a rare and life-threatening state of thyroid hormone excess. Rapid recognition of thyroid storm is key to decreasing the morbidity and mortality of this condition. Clinical manifestations of thyroid storm include unexplained weight loss, hyperactivity and irritability. Read More

    Lancet 2016 Aug 30;388(10047):906-918. Epub 2016 Mar 30.
    Endocrine Unit, Fondazione IRCCS Cà Granda, Milan, Italy (S De Leo MD); Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy (S De Leo); and Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA (S De Leo, S Y Lee MD, Prof L E Braverman MD).
    Hyperthyroidism is characterised by increased thyroid hormone synthesis and secretion from the thyroid gland, whereas thyrotoxicosis refers to the clinical syndrome of excess circulating thyroid hormones, irrespective of the source. The most common cause of hyperthyroidism is Graves' disease, followed by toxic nodular goitre. Other important causes of thyrotoxicosis include thyroiditis, iodine-induced and drug-induced thyroid dysfunction, and factitious ingestion of excess thyroid hormones. Read More

    Onset of ulcerative colitis after thyrotoxicosis: a case report and review of the literature.
    Eur Rev Med Pharmacol Sci 2016 ;20(4):685-8
    Department of Internal Medicine, Gastroenterology and Liver Disease, Catholic University of the Sacred Heart of Rome, Rome, Italy.
    Objective: Ulcerative colitis is a chronic disease that could be triggered by acute stressful events, such as gastrointestinal infections or emotional stress.

    Patients And Methods: We reported the case of the onset of an ulcerative colitis after a thyrotoxicosis crisis and reviewed the literature about the relationships between thyroid dysfunctions and ulcerative colitis.

    Results: A 38-year-old woman was diagnosed with ulcerative colitis after her third thyrotoxicosis crisis, two years after the diagnosis of Graves' disease. Read More

    Impact of thyroidectomy on cardiac manifestations of Graves' disease.
    Laryngoscope 2016 05 1;126(5):1256-9. Epub 2016 Mar 1.
    Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.
    Objectives/hypothesis: Graves' disease (GD) has multiple adverse effects on the cardiovascular system. We aimed to examine the outcome of thyroidectomy in patients with cardiac manifestations of GD and evaluate their associated postoperative complications.

    Study Design: Retrospective analysis using a prospectively collected database. Read More

    Sudden cardiac arrest as a presentation of Brugada syndrome unmasked by thyroid storm.
    BMJ Case Rep 2015 Dec 30;2015. Epub 2015 Dec 30.
    Department of Intensive Care, Gelderse Vallei Hospital, Ede, The Netherlands.
    An 18-year-old man suffered a sudden cardiac arrest with ventricular fibrillation and was successfully resuscitated. He had neither a medical nor family history of cardiac disease/sudden death, but was known to have Graves' disease, for which he was treated with radioactive iodine. Recently, block-and-replacement therapy had been discontinued to evaluate thyroid functioning. Read More

    Thyroid storm in a patient with Wolff-Parkinson-White syndrome.
    BMJ Case Rep 2015 Dec 15;2015. Epub 2015 Dec 15.
    Department of Endocrinology, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
    A 44-year-old woman with no medical history presented to the emergency department with a 2 h history of sudden onset chest pressure, palpitations, diaphoresis and shortness of breath. She reported a 90-pound unintentional weight loss, increased appetite, irritability, night sweats and palpitations for 2 months. Physical examination revealed a heart rate (HR) of 269 bpm and a blood pressure of 116/94 mm Hg. Read More

    Simultaneous occurrence of diabetic ketoacidosis, thyroid storm, and multiple cerebral infarctions due to Moyamoya disease.
    J Pediatr Endocrinol Metab 2016 Feb;29(2):221-5
    Diabetic ketoacidosis (DKA) is one of the precipitating factors that can evoke a thyroid storm. Thyroid storm may cause cerebral ischemia in Moyamoya disease, which can coexist in patients with Graves' disease. A 16-year-old girl complaining of dizziness and palpitations visited the emergency department and was diagnosed with DKA combined with hyperthyroidism. Read More

    Hyperthyroidism in children.
    Pediatr Rev 2015 Jun;36(6):239-48
    Pediatric Endocrine Unit, Massachusetts General Hospital for Children and Harvard Medical School, Boston, MA.
    On the basis of strong research evidence, hyperthyroidism is a rare but potentially serious disorder in childhood that, if uncontrolled, can lead to a wide range of complications, including effects on growth and development. • On the basis of strong research evidence, Graves' disease is the most common cause of hyperthyroidism in children, accounting for greater than 95% of cases. It is caused by stimulating antibodies to the thyroid-stimulating hormone receptor. Read More

    Thyroid diseases during pregnancy: a number of important issues.
    Hormones (Athens) 2015 Jan-Mar;14(1):59-69
    Department of Endocrinology, St. Paul Hospital, Thessaloniki, Greece.
    The most common thyroid diseases during pregnancy are hyper- and hypothyroidism and their variants including isolated hypothyroxinemia (hypo-T4), autoimmune thyroid disease (AITD) and different types of goiter. AITD represents the main cause of hypothyroidism during pregnancy ranging in prevalence between 5 and 20% with an average of 7.8%. Read More

    Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease.
    Intern Med 2015 1;54(7):813-8. Epub 2015 Apr 1.
    Department of Medicine, Diabetes, Metabolism and Endocrinology, Matsuyama Red Cross Hospital, Japan.
    We herein describe a case of hypercalcemic crisis in a 52-year-old Japanese woman. She suffered from thirst and fatigue for one month. Her serum calcium (a) levels were 19. Read More

    Neonatal thyroid storm accompanied with severe anaemia.
    J Pediatr Endocrinol Metab 2015 Jul;28(7-8):773-6
    Neonatal thyroid storm is rare; the diagnostic criteria and management of neonatal thyroid storm have not been well established. In this paper, we report a preterm infant diagnosed with neonatal hyperthyroidism secondary to maternal Graves' disease who was discharged after therapy. Unfortunately, he was rehospitalised for neonatal thyroid storm. Read More

    A 46-Year-Old Woman With Dyspnea From an Inhalational Exposure, Triggering Thyroid Storm and Subsequent Multi-Organ System Failure.
    J Intensive Care Med 2015 Dec 12;30(8):518-20. Epub 2015 Feb 12.
    UMass Memorial Medical Center, Department of Pulmonary, Allergy and Critical Care, Worcester, MA, USA.
    Background: Thyroid storm is a rare, life-threatening condition which arises in patients with thyrotoxicosis, with an annual incidence of 2 patients per 1,000,000 and a mortality rate of 11%.

    Case: We present the case of a 46-year-old-female with a medical history of controlled mild intermittent asthma, who presented with a severe asthma exacerbation, that triggered thyroid storm after exposure to polyurethane fumes.

    Conclusion: This patient represents, to the best of our knowledge, the first patient in whom the stress related to a severe asthma attack triggered the development of thyroid storm. Read More

    Jod-Basedow effect due to prolonged use of lugol solution-case report.
    Rev Med Chir Soc Med Nat Iasi 2014 Oct-Dec;118(4):1013-7
    University of Medicine and Pharmacy Grigore T. Popa - Iaşi, Department of Medical Specialties (II).
    Graves' disease is the most common form of hyperthyroidism, accounting for 60-80% of all cases of thyrotoxicosis. If left untreated, it may lead to severe thyrotoxicosis with cardiovascular, ocular, psychiatric complication, and in extreme cases thyrotoxic crisis with a high mortality rate. We present the case of a 50-years-old woman diagnosed in another service with Graves' disease and treated for many years with antithyroid drugs (ATDs), admitted to our service for a relapse due to treatment discontinuation. Read More

    [Prolonged psychosis associated with thyrotoxicosis during the subacute stage of cardioembolic stroke in a patient with untreated basedow disease].
    Brain Nerve 2014 Dec;66(12):1509-14
    Department of Neurology, Fukuoka University Faculty of Medicine.
    A 57-year-old female developed dizziness and forgetfulness several days before admission. She was admitted to our hospital because of a headache and nausea. On admission, she had a mild disturbance of consciousness and right hemiparesis. Read More

    Hashimoto's encephalopathy: report of three cases.
    J Formos Med Assoc 2014 Nov 3;113(11):862-6. Epub 2012 Mar 3.
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:
    Both severe thyrotoxicosis and hypothyroidism may affect brain function and cause a change in consciousness, as seen with a thyroid storm or myxedema coma. However, encephalopathy may also develop in patients with autoimmune thyroid diseases independent of actual thyroid function level, and this is known as Hashimoto's encephalopathy. Although most patients are found to have Hashimoto's thyroiditis, less frequently they have Graves' disease. Read More

    Review of oral cholecystographic agents for the management of hyperthyroidism.
    Endocr Pract 2014 Oct;20(10):1084-92
    Department of Medicine, University of California, Los Angeles, Los Angeles, California.
    Objective: Although the use of oral cholecystographic agents (OCAs) had declined due to limited availability, there is literature to suggest it is an effective medication for thyrotoxicosis in appropriate clinical situations.

    Methods: The authors performed a PubMed search and systematically reviewed all the English written case reports, original studies and reviews from 1953 to 2012. Additional information was supplemented from available online pharmacologic databases. Read More

    L-carnitine treatment in a seriously ill cancer patient with severe hyperthyroidism.
    Hormones (Athens) 2014 Jul-Sep;13(3):407-12
    Section of Endocrinology, Department of Clinical & Experimental Medicine, University of Messina, Messina, Interdepartmental Program of Molecular & Clinical Endocrinology and Women's Endocrine Health, A.O.U. Policlinico G. Martino, Italy.
    Objective: To report a case of vaccine-induced Graves' disease successfully managed with L-carnitine and propranolol and without antithyroid drugs (ATDs). ATDs sometimes need to be used at low doses or can be contraindicated/refused. One of the ancillary compounds available is L-carnitine. Read More

    [Oedema and haemorrhagic diathesis in a 50-year-old woman with thyrotoxicosis].
    Internist (Berl) 2014 Nov;55(11):1352-5
    Abteilung für Innere Medizin, St. Josef-Hospital Troisdorf, Hospitalstr. 45, 53840, Troisdorf, Deutschland,
    We describe the case of a 50-year-old woman who presented with tachyarrhythmia, mild fever, peripheral oedema, ascites, epistaxis and gastrointestinal haemorrhage. Blood analysis revealed hyperthyroxinaemia. Analysis of thyroid-stimulating antibodies highlighted Graves' disease being the cause of the prevailing thyrotoxic crisis. Read More

    Sudden unexpected death in the setting of undiagnosed Graves' disease.
    Forensic Sci Med Pathol 2014 Sep 1;10(3):452-6. Epub 2014 Jun 1.
    Department of Forensic Medicine, Victorian Institute of Forensic Medicine, Monash University, 57-83 Kavanagh Street, Southbank, VIC, 3006, Australia,
    Graves' disease is the most common cause of hyperthyroidism and is classically characterized by the clinical triad of diffuse toxic goiter, infiltrative ophthalmopathy with exophthalmos and an infiltrative dermopathy. While the name of the Irishman Robert Graves has received the eponymous honor, the first description of the condition in the English language can be attributed to the Englishman Caleb Perry, while in continental Europe the entity in name once honored Karl von Basedow. We present the case of a previously well 43 year old woman who presented in supraventricular tachycardia and acute pulmonary edema and died despite treatment and without a diagnosis for cause of death. Read More

    Thyroid storm following radioactive iodine (RAI) therapy for pediatric graves disease.
    Am J Case Rep 2014 14;15:212-5. Epub 2014 May 14.
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, U.S.A.
    Patient: Female, 11 FINAL DIAGNOSIS: Thyroid storm Symptoms: Diarrhea • tachycardia • tachypnea • tremor • wheezing

    Medication: - Clinical Procedure: - Specialty: -

    Objective: Rare disease.

    Background: A growing number of pediatric endocrinologists treat Graves disease with radioactive iodine (RAI) therapy due to the typically definitive nature of I-131 therapy. Given the published benefits and perceived low risks of RAI when compared to surgery or long-term anti-thyroid medication, the trend towards therapy with RAI is likely to continue. Read More

    Hyperthyroidism and thyrotoxicosis.
    Emerg Med Clin North Am 2014 May 15;32(2):277-92. Epub 2014 Mar 15.
    Department of Emergency Medicine, University of Maryland Medical System, University of Maryland, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA.
    Hyperthyroidism and thyrotoxicosis are hypermetabolic conditions that cause significant morbidity and mortality. The diagnosis can be difficult because symptoms can mimic many other disease states leading to inaccurate or untimely diagnoses and management. Thyroid storm is the most severe form of thyrotoxicosis, hallmarked by altered sensorium, and, if untreated, is associated with significant mortality. Read More

    A case of thyroid storm with a markedly elevated level of circulating soluble interleukin-2 receptor complicated by multiple organ failure and disseminated intravascular coagulation syndrome.
    Endocr J 2014 20;61(7):691-6. Epub 2014 May 20.
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
    Thyroid storm (TS) is a life-threatening endocrine emergency. However, the pathogenesis of TS is poorly understood. A 40-year-old man was admitted to a nearby hospital with body weight loss and jaundice. Read More

    Glucose variability before and after treatment of a patient with Graves' disease complicated by diabetes mellitus: assessment by continuous glucose monitoring.
    Endocr J 2014 11;61(4):321-8. Epub 2014 Jan 11.
    First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushyu 807-8555, Japan.
    A 48-year-old woman was diagnosed and treated for Graves' disease (GD) in 1999 but she discontinued treatment at her own discretion. In 2011, she was admitted to a local hospital for management of thyrotoxic crisis. Treatment with propylthiouracil, iodide potassium (KI), and prednisolone (PSL) was started, which resulted in improvement of the general condition. Read More

    Thyroid disease and the nervous system.
    Handb Clin Neurol 2014 ;120:703-35
    Sheffield Institute for Translational Neuroscience, University of Sheffield and Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK. Electronic address:
    Thyroid disorders are common in the general population and in hospitalized patients. Thyroid disease may present first with neurological complications or else may occur concurrently in patients suffering other neurological disorders, particularly those with an autoimmune etiology. For this reason neurologists will commonly encounter patients with thyroid disease. Read More

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