1,187 results match your criteria Hyperthyroidism Thyroid Storm & Graves Disease


Sepsis and thyroid storm in a patient with methimazole-induced agranulocytosis.

BMJ Case Rep 2020 Jul 6;13(7). Epub 2020 Jul 6.

Department of Pediatrics, University of Kentucky, Lexington, Kentucky, USA.

Paediatric hyperthyroidism cases are mostly caused by Grave's disease. Thyroid storm is a life-threatening condition seen rarely, in severe thyrotoxicosis, occurring in about 1%-2% of patients with hyperthyroidism. Antithyroid medications and beta-blockers are typically the first-line management of thyroid storm. Read More

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http://dx.doi.org/10.1136/bcr-2020-235536DOI Listing

Acute Flaccid Quadriplegic Myopathy and Encephalopathy with Extensive Muscle Magnetic Resonance Imaging Changes in Thyroid Storm.

Ann Indian Acad Neurol 2020 May-Jun;23(3):342-344. Epub 2020 Jun 10.

Ajantha Clinic, Kochi, Kerala, India.

Thyroid storm (TS) is a rare hyperthyroidism associated multisystem decompensation and can mimic a systemic inflammatory response syndrome. It is diagnosed in the presence of fever with cardiovascular, central nervous system, and gastrointestinal complications. Only a few reports of acute flaccid quadriplegic thyrotoxic myopathy (TM) with TS have been reported. Read More

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http://dx.doi.org/10.4103/aian.AIAN_358_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313581PMC

[Iodine-induced thyroid dysfunction].

Med Klin Intensivmed Notfmed 2020 Jun 24. Epub 2020 Jun 24.

Klinik für Allgemeine Innere Medizin, Endokrinologie, Diabetologie, Infektiologie, Klinikum Bielefeld Mitte, Bielefeld, Deutschland.

Background: Iodine-induced thyroid dysfunctions are, despite their rare occurrence, important clinical syndromes. Their immediate recognition can avoid serious consequences. Important triggers can be iodine-containing contrast agents, amiodarone or iodine-containing disinfectants. Read More

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http://dx.doi.org/10.1007/s00063-020-00699-8DOI Listing

Therapeutic Plasma Exchange Combined with Total Thyroidectomy to Rescue a Case of Thyroid Storm Intolerant to Antithyroid Drugs.

J Coll Physicians Surg Pak 2020 May;30(5):532-534

Department of Endocrinology, Second Hospital of Lanzhou University, China.

Thyroid storm is a syndrome related to acute exacerbation of thyrotoxicosis for which timely diagnosis and treatment are crucial. Importance of antithyroid drug therapy in thyroid storm patients has been emphasised in clinical treatments for a long time. These patients should receive definitive therapy for their underlying hyperthyroidism to avoid recurrence after controlling thyroid storm. Read More

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http://dx.doi.org/10.29271/jcpsp.2020.05.532DOI Listing

Perioperative Management and Outcomes of Hyperthyroid Patients Unable to Tolerate Antithyroid Drugs.

World J Surg 2020 Jun 22. Epub 2020 Jun 22.

Section of Endocrine Surgery, Division of Surgical Oncology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, USA.

Background: Prior to thyroidectomy for hyperthyroidism, it is recommended that patients are managed with antithyroid drugs (ATDs) and rendered euthyroid to decrease the risk of thyroid storm. However, not all patients tolerate ATD and the risk of thyroid storm during thyroidectomy in these patients is unclear. Therefore, the aim of this study was to compare the management and outcomes of hyperthyroid patients that were on ATDs prior to surgery to those who were not. Read More

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http://dx.doi.org/10.1007/s00268-020-05654-4DOI Listing

A case of thyroxine (T4) toxicosis complicated by thyroid storm with an unusual precipitant.

Caspian J Intern Med 2020 ;11(2):231-234

Endocrinology, Diabetes and Metabolism Division, Department of Internal Medicine, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.

Background: Thyrotoxicosis, though commonly encountered in endocrinology practice in Nigeria, seldom presents solely as thyroxine (T4) toxicosis. Thyroid storm, a known life-threatening complication of thyrotoxicosis, can be precipitated by myriad factors. Fine need aspiration for cytology is not known, and has not been previously reported (to the best of our knowledge) to precipitate thyroid storm. Read More

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http://dx.doi.org/10.22088/cjim.11.2.231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265511PMC
January 2020

ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of hyperthyroidism and hypothyroidism.

Eur J Endocrinol 2020 Jul;183(1):G33-G39

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

This manuscript provides guidance on the management of thyroid dysfunction during the COVID-19 pandemic. Autoimmune thyroid diseases are not linked to increased risks of COVID-19. Uncontrolled thyrotoxicosis may result in more severe complications from SARS-CoV-2 infection, including thyroid storm. Read More

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http://dx.doi.org/10.1530/EJE-20-0445DOI Listing

Strangulation-Induced Thyrotoxicosis in a Patient with Undiagnosed Underlying Graves' Disease.

Case Rep Endocrinol 2020 19;2020:7986581. Epub 2020 Mar 19.

Reading Hospital, Wyomissing, USA.

Thyrotoxicosis is a constellation of symptoms including palpitations, tremors, agitation, and heat intolerance, caused by excess thyroid hormone. It can be life-threatening in its most serious form. We present a rare case of thyrotoxicosis provoked by mechanical trauma to the neck via strangulation in a young female with a history of self-resolving postpartum symptoms of hyperthyroidism one year prior, but no formal diagnosis of thyroid dysfunction. Read More

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http://dx.doi.org/10.1155/2020/7986581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106904PMC

Hyperthyroidism.

Gland Surg 2020 Feb;9(1):124-135

Division of Endocrine Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

Hyperthyroidism is a condition where the thyroid gland produces and secretes inappropriately high amounts of thyroid hormone which can lead to thyrotoxicosis. The prevalence of hyperthyroidism in the United States is approximately 1.2%. Read More

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http://dx.doi.org/10.21037/gs.2019.11.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082267PMC
February 2020

An uncommon cause of fever in a patient with hyperthyroidism.

J Family Med Prim Care 2020 Jan 28;9(1):432-434. Epub 2020 Jan 28.

Department of Endocrinology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

Fever as an indicator of disease has always been and remains a clinical symptom of great importance. It may be a manifestation of any inflammatory process of the thyroid and also may be presenting feature of thyroid storm. Melioidosis, is an infection caused by the gram negative bacterium Burkholderia pseudomallei and the commonest co-morbidity observed in India is diabetes mellitus. Read More

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http://dx.doi.org/10.4103/jfmpc.jfmpc_933_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014895PMC
January 2020

Thyroid Storm in a Toddler Presenting as a Febrile Seizure.

Pediatrics 2020 02;145(2)

Division of Pediatric Endocrinology, Department of Pediatrics and.

Although simple febrile seizures are relatively common and benign in toddlers, it is important to rule out any underlying critical disease that necessitates further intervention and treatment. Thyroid storm, the extreme manifestation of hyperthyroidism, is relatively rare and not often considered in the differential diagnosis of a febrile seizure despite its high mortality rate. Here, we report 1 of the youngest patients with thyroid storm, who initially presented with a febrile seizure. Read More

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http://dx.doi.org/10.1542/peds.2019-1920DOI Listing
February 2020

FLAIL MITRAL VALVE: A RARE COMPLICATION OF A THYROID STORM.

AACE Clin Case Rep 2019 Jan-Feb;5(1):e4-e6. Epub 2019 Jan 30.

Objective: Thyroid storm is a life-threatening presentation, with heart failure and tachyarrhythmias being common manifestations. This case highlights that a flail mitral valve from chordae tendineae rupture can be a cause of worsening heart failure and cardiogenic shock in a thyroid storm, albeit a rare complication.

Methods: We describe a patient who was admitted for a thyroid storm precipitated by pneumonia, who later developed an acute flail mitral valve from chordae tendineae rupture. Read More

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http://dx.doi.org/10.4158/ACCR-2018-0137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876983PMC
January 2019

Thyroid storm after coronary artery bypass surgery: a case report.

Authors:
Jae Hoon Lee

J Cardiothorac Surg 2020 Jan 16;15(1):22. Epub 2020 Jan 16.

Department of Thoracic and Cardiovascular Surgery, Sanggye Paik Hospital, Inje University School of Medicine, 1342 Dongil-ro, Nowon-gu, Seoul, South Korea.

Background: Thyroid storm is a rare, life-threatening disease triggered by an acute event or trauma, such as surgery of the thyroid or another area, and infection. However, recent studies have shown that irregular use or discontinuation of antithyroid drugs is the most common cause of thyroid storm. A cardiovascular event caused by thyroid storm following coronary artery bypass graft (CABG) is high output heart failure with extreme tachycardia, which can be fatal. Read More

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http://dx.doi.org/10.1186/s13019-020-1044-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964208PMC
January 2020

Thyroid storm: Is there a role for thyroid function test?

Malays J Pathol 2019 Dec;41(3):355-358

Universiti Putra Malaysia, Faculty of Medicine & Health Sciences, Department of Pathology, Serdang, Malaysia.

Introduction: Thyroid storm (TS) is an endocrine emergency. Early diagnosis for prompt treatment is essential as it has a high mortality rate.

Case Report: A 31-year-old lady with underlying hyperthyroidism, dilated cardiomyopathy with severe mitral regurgitation presented with shortness of breath. Read More

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December 2019

Gestational Trophoblastic Disease-induced Thyroid Storm.

Clin Pract Cases Emerg Med 2019 Nov 21;3(4):409-412. Epub 2019 Oct 21.

Temple University Hospital, Department of Emergency Medicine, Philadelphia, Pennsylvania.

In the United States, gestational trophoblastic diseases (GTD), including molar pregnancies, occur in 121 out of 100,000 pregnancies.1 Many patients with GTD may develop hyperthyroidism. GTD-induced thyroid storm is a rare but life-threatening complication of GTD. Read More

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http://dx.doi.org/10.5811/cpcem.2019.9.43656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861026PMC
November 2019

Thyroid Storm in the ICU: A Retrospective Multicenter Study.

Crit Care Med 2020 01;48(1):83-90

Assistance Publique-Hôpitaux de Paris (APHP), Pitié-Salpêtrière Hospital, Medical Intensive Care Unit, 75651 Paris Cedex 13, Paris, France.

Objectives: Thyroid storm represents a rare but life-threatening endocrine emergency. Only rare data are available on its management and the outcome of the most severe forms requiring ICU admission. We aimed to describe the clinical manifestations, management and in-ICU and 6-month survival rates of patients with those most severe thyroid storm forms requiring ICU admission. Read More

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http://dx.doi.org/10.1097/CCM.0000000000004078DOI Listing
January 2020
5 Reads

Thyroid Storm with Multiorgan Failure Treated with Plasmapheresis.

Case Rep Endocrinol 2019 9;2019:2475843. Epub 2019 Oct 9.

Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.

Background: Thyroid storm is a severe manifestation of thyrotoxicosis and can present with multiorgan failure. First line treatment of thyroid storm is directed towards decreasing thyroid hormone production and peripheral conversion of T4 to T3, and treating adrenergic symptoms. When medical therapy fails, plasmapheresis is an alternative treatment option. Read More

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http://dx.doi.org/10.1155/2019/2475843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811794PMC
October 2019
1 Read

Immune checkpoint inhibitor-associated thyroid dysfunction: a disproportionality analysis using the WHO Adverse Drug Reaction Database, VigiBase.

Eur J Endocrinol 2020 Jan;182(1):1-9

Department of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou City, Fujian Province, China.

Objective: Our study aimed to identify and characterize thyroid dysfunctions associated with immune checkpoint inhibitors (ICIs).

Design: Data were obtained from VigiBase, between January 1, 2011 to March 6, 2019.

Methods: All thyroid drug-adverse events are classified by group queries according to the Medical Dictionary for Regulatory Activities. Read More

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http://dx.doi.org/10.1530/EJE-19-0535DOI Listing
January 2020
1 Read

Hungry bone syndrome after thyroidectomy for thyroid storm.

BMJ Case Rep 2019 Oct 10;12(10). Epub 2019 Oct 10.

Metabolism and Endocrinology, Kanto Central Hospital of the Mutual Aid Association of Public School Teachers, Setagaya-ku, Tokyo, Japan.

A 39-year-old man was admitted to our hospital with the diagnosis of thyroid storm due to Graves' disease. Near-total thyroidectomy was performed after 1 month's pharmacological treatment, and he presented with tetany next morning. Serum corrected calcium value was 5. Read More

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http://dx.doi.org/10.1136/bcr-2019-231411DOI Listing
October 2019
2 Reads

Fulminant hepatitis and elevated levels of sIL-2R in thyroid storm.

Endocrinol Diabetes Metab Case Rep 2019 Sep 27;2019. Epub 2019 Sep 27.

Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Summary: We report the case of a 48-year-old man with thyroid storm associated with fulminant hepatitis and elevated levels of soluble interleukin-2 receptor (sIL-2R). Fatigue, low-grade fever, shortness of breath, and weight loss developed over several months. The patient was admitted to the hospital because of tachycardia-induced heart failure and liver dysfunction. Read More

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http://dx.doi.org/10.1530/EDM-19-0078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765318PMC
September 2019
1 Read

McCune-Albright Syndrome With Unremitting Hyperthyroidism at Early Age: Management Perspective for Early Thyroidectomy.

Glob Pediatr Health 2019 9;6:2333794X19875153. Epub 2019 Sep 9.

Baylor College of Medicine, Houston, TX, USA.

. McCune-Albright syndrome (MAS) is characterized by hyperpigmented macules, endocrinopathies, and fibrous dysplasia. Hyperthyroidism is the second most common endocrinopathy in MAS and its management is challenging, particularly among infants and toddlers. Read More

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http://dx.doi.org/10.1177/2333794X19875153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734602PMC
September 2019
1 Read

Thyroid Storm-induced Severe Dilated Cardiomyopathy and Ventricular Tachycardia.

Cureus 2019 Jul 4;11(7):e5079. Epub 2019 Jul 4.

Cardiology, University of Central Florida College of Medicine/Hospital Corporation of America Graduate Medical Education Consortium, Orlando, USA.

Thyroid storm is an extreme form of hyperthyroidism associated with a high mortality rate. Heart failure is considered the leading cause of mortality in patients with thyroid storm, though the underlying cardiac pathology is unclear. Approximately 6% of patients with thyroid storm have heart failure symptoms as the initial presenting complaint. Read More

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https://www.cureus.com/articles/19670-thyroid-storm-induced-
Publisher Site
http://dx.doi.org/10.7759/cureus.5079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726417PMC
July 2019
20 Reads

[Thyroid storm and exacerbation of autoimmune hemolytic anemia following childbirth].

Rinsho Ketsueki 2019 ;60(8):924-928

Department of Hematology, Gunma University Graduate School of Medicine.

A 32-year-old woman was diagnosed with autoimmune hemolytic anemia (AIHA) at 12 weeks of a pregnancy examination and followed up closely without treatment. At 40 weeks of gestation, she underwent emergency caesarean section because of premature rupture. On postoperative day one, the patient exhibited worsening hemolysis and tachycardia and developed high-output heart failure; she was diagnosed with Basedow disease based on the tachycardia pattern and thyroid storm based on the presence of hyperthyroidism, fever, tachycardia, and heart failure. Read More

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http://dx.doi.org/10.11406/rinketsu.60.924DOI Listing
September 2019
5 Reads

Atypical presentation of thyroid storm: a diagnostic dilemma.

BMJ Case Rep 2019 Aug 26;12(8). Epub 2019 Aug 26.

Critical and Intensive Care, All India Institute of Medical Sciences, New Delhi, India.

Thyroid storm (accelerated hyperthyroidism) is an uncommon life-threatening emergency. The diagnosis is difficult and at times delayed owing to atypical presentation. Early diagnosis is the key to its successful management. Read More

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http://dx.doi.org/10.1136/bcr-2019-231090DOI Listing
August 2019
2 Reads

Intramuscular levothyroxine: a solution to a mental health related thyroid crisis.

BMJ Case Rep 2019 Aug 20;12(8). Epub 2019 Aug 20.

Diabetes and Endocrinology, Homerton University Hospital NHS Foundation Trust, London, UK.

A 53-year-old woman was admitted with thyroid storm and severe behavioural problems. She had longstanding bipolar affective disorder. She was psychotic and obstructed in-patient medical management for thyroid storm. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22814
Publisher Site
http://dx.doi.org/10.1136/bcr-2018-228147DOI Listing
August 2019
4 Reads

Candida tropicalis Thyroiditis Presenting With Thyroid Storm in a Pediatric Patient With Acute Lymphocytic Leukemia.

Pediatr Infect Dis J 2019 10;38(10):1051-1053

From the Section of Infectious Diseases, Department of Pediatrics.

Suppurative thyroiditis is uncommon in the pediatric population and particularly rare to be caused by fungi. We present a case of Candida tropicalis thyroiditis in an adolescent male with acute lymphocytic leukemia that led to disseminated candidiasis, thyroid storm and eventual total thyroidectomy for source control. Read More

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http://dx.doi.org/10.1097/INF.0000000000002424DOI Listing
October 2019
2 Reads

Thyrotoxicosis-induced cardiomyopathy treated with venoarterial extracorporeal membrane oxygenation.

Heart Lung 2020 Mar - Apr;49(2):165-166. Epub 2019 Jul 5.

Department of Medicine, Division of Cardiology, Loyola University Medical Center, 2160 S First Ave, Suite 6232-6234, Maywood, 60153 IL, USA. Electronic address:

A 37-year-old woman with no past medical history presented with longstanding untreated hyperthyroidism and consequentially developed thyrotoxicosis-induced cardiomyopathy. Upon admission, she was noted with a heart rate of 172 beats per minute and an EKG consistent with supraventricular tachycardia which was unresponsive to adenosine. Shortly after the initiation of a non-cardioselective beta-blocker for the treatment of persistent tachycardia, she developed profound cardiogenic shock refractory to vasopressors and inotropes. Read More

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http://dx.doi.org/10.1016/j.hrtlng.2019.06.006DOI Listing
July 2019
9 Reads

Postpartum Thyroid Storm in Poorly Controlled Graves' Disease: A Case Report.

A A Pract 2019 Oct;13(8):299-302

From the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Hyperthyroidism during pregnancy is a relatively rare event, but poor control of hyperthyroidism during pregnancy is associated with a host of issues. These include intrauterine fetal demise, hypertensive disorders of pregnancy, preterm delivery, low birth weight, intrauterine growth restriction, and maternal congestive heart failure. One of the most feared sequelae of hyperthyroidism is thyroid storm, which has a mortality rate >10%. Read More

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http://dx.doi.org/10.1213/XAA.0000000000001059DOI Listing
October 2019
3 Reads

Thyroid emergencies.

Pol Arch Intern Med 2019 08 25;129(7-8):526-534. Epub 2019 Jun 25.

Endocrinology Division, Department of Medicine, Georgetown University School of Medicine, Washington DC, United States

Myxedema coma and thyroid storm are among the most common endocrine emergencies presenting to general hospitals. Myxedema coma represents the most extreme, life‑threatening expression of severe hypothyroidism, with patients showing deteriorating mental status, hypothermia, and multiple organ system abnormalities. It typically appears in patients with preexisting hypothyroidism via a common pathway of respiratory decompensation with carbon dioxide narcosis leading to coma. Read More

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http://dx.doi.org/10.20452/pamw.14876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721612PMC
August 2019
10 Reads

High-output congestive heart failure: a potentially deadly complication of thyroid storm.

Oxf Med Case Reports 2019 Jun 14;2019(6):omz045. Epub 2019 Jun 14.

Beaumont Hospital-Farmington Hills, MI. USA. Teaching Hospital of Michigan State University. Departments of Emergency Medicine and Internal Medicine.

Hyperthyroidism, thyrotoxicosis and thyroid storm are a continuum of disease. A life-threatening and potentially fatal manifestation of thyrotoxicosis is thyroid storm. Thyroid storm is considered rare with an occurrence rate of 1-2% of all patients with hyperthyroidism, making a high index of suspicion important in the early recognition of this debilitating complication. Read More

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http://dx.doi.org/10.1093/omcr/omz045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568196PMC
June 2019
4 Reads

A 'Natural' thyroid storm!

J Clin Pharm Ther 2019 Oct 18;44(5):813-814. Epub 2019 Jun 18.

Department of Physiology and Pharmacology, University of the Pacific, Stockton, California.

What Is Known And Objective: Over the counter supplements are often taken for granted during medication reconciliation in the emergency department. Supplements are not regulated by FDA, and some can be potentially dangerous.

Case Summary: We report a case of thyrotoxicosis secondary to over the counter bovine thyroid supplements. Read More

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http://dx.doi.org/10.1111/jcpt.12996DOI Listing
October 2019
9 Reads

Concurrent presentation of thyroid storm and diabetic ketoacidosis: a systematic review of previously reported cases.

BMC Endocr Disord 2019 May 17;19(1):49. Epub 2019 May 17.

Department of Pharmacology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, 50008, Sri Lanka.

Background: Simultaneous development of thyroid storm and diabetic ketoacidosis (DKA) is a rare condition. The review aims to summarise its clinical presentation, investigation findings and treatment options.

Methods: Databases and reference lists of the selected articles were searched for case reports in English which describe concurrent presentation of thyroid storm and diabetic ketoacidosis. Read More

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http://dx.doi.org/10.1186/s12902-019-0374-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525384PMC
May 2019
3 Reads

[Thyroid storm].

MMW Fortschr Med 2019 May;161(9):54-55

BG Universitätsklinikum Bergmannsheil gGmbH, Bochum, Deutschland.

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http://dx.doi.org/10.1007/s15006-019-0514-8DOI Listing
May 2019
9 Reads

Assessment of Molecular Subtypes in Thyrotoxic Periodic Paralysis and Graves Disease Among Chinese Han Adults: A Population-Based Genome-Wide Association Study.

JAMA Netw Open 2019 05 3;2(5):e193348. Epub 2019 May 3.

The Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People's Hospital, State Key Laboratory of Medical Genomics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Importance: Thyrotoxic periodic paralysis (TPP) is a potentially lethal complication of hyperthyroidism. However, only 1 specific susceptibility locus for TPP has been identified. Additional genetic determinants should be detected so that a prediction model can be constructed. Read More

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2019.3348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503496PMC
May 2019
13 Reads

Severe Myasthenic Manifestation of Leptospirosis Associated with New Sequence Type of Leptospira interrogans.

Emerg Infect Dis 2019 05;25(5):968-971

We report the rapid development of a myasthenic crisis as the first-time manifestation of myasthenia gravis. The symptoms developed in the course of acute leptospirosis associated with a new sequence type of Leptospira interrogans. Antibiotic treatment led to rapid amelioration of myasthenia. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1591_article.htm
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http://dx.doi.org/10.3201/eid2505.181591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478190PMC
May 2019
7 Reads

The Delayed Diagnosis of Thyroid Storm in Patients with Psychosis.

Intern Med 2019 Aug 17;58(15):2195-2199. Epub 2019 Apr 17.

Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center, Japan.

We herein report two cases of patients with thyroid storm with a delayed diagnosis due to psychosis. The patients were a 63-year-old woman with bipolar II disorder and a 37-year-old man with major depressive disorder. The psychoses in both patients were well controlled with medication. Read More

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http://dx.doi.org/10.2169/internalmedicine.2681-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709321PMC
August 2019
4 Reads

Endocrine Emergencies in Obstetrics.

Clin Obstet Gynecol 2019 06;62(2):339-346

Department of Obstetrics/Gynecology, Division of Maternal Fetal Medicine, Medical University of South Carolina, Charleston, South Carolina.

Endocrine emergencies in pregnancy can be life threatening and are associated with increased morbidity for both the mother and fetus. Thyroid storm, diabetic ketoacidosis, and hypercalcemic crisis require a high clinical suspicion, rapid treatment, and multidisciplinary care to ensure best outcomes. Critical care consultation and intensive care unit admission are often warranted. Read More

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http://dx.doi.org/10.1097/GRF.0000000000000433DOI Listing
June 2019
4 Reads

Management of Endocrine Emergencies in the ICU.

Authors:
Judith Jacobi

J Pharm Pract 2019 Jun 10;32(3):314-326. Epub 2019 Mar 10.

1 Pharmacy Department, Indiana University Health Methodist Hospital, Indianapolis, IN, USA.

Endocrine emergencies are frequent in critically ill patients and may be the cause of admission or can be secondary to other critical illness. The ability to anticipate endocrine abnormalities such as adrenal excess or , hypothyroidism, can mitigate their duration and severity. Hyperglycemic crisis may trigger hospital and intensive care unit (ICU) admission and may be life threatening. Read More

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http://dx.doi.org/10.1177/0897190019834771DOI Listing
June 2019
6 Reads

Therapeutic plasma exchange and continuous renal replacement therapy for severe hyperthyroidism and multi-organ failure: A case report.

World J Clin Cases 2019 Feb;7(4):500-507

Department of Medical Intensive Unit, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.

Background: Severe hyperthyroidism is a life-threatening exacerbation of thyrotoxicosis, characterized by high fever and multiorgan failure. The most common medical treatments are administration of antithyroid drugs and radioactive iodine, and thyroidectomy. In some patients, antithyroid therapy is limited due to serious adverse effects or failure to control disease progression. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i4.500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397818PMC
February 2019
10 Reads

The value of total thyroidectomy as the definitive treatment for Graves' disease: A single centre experience of 594 cases.

J Clin Transl Endocrinol 2019 Jun 7;16:100183. Epub 2019 Feb 7.

University of Palermo, Department of Surgical Oncological and Oral Sciences, Division of General and Oncological Surgery, Palermo, Italy.

Purpose: Thyroidectomy is the preferred approach as the definitive treatment for Graves' disease. The outcomes for total thyroidectomy in a large series of 594 patients, who were observed in the last decade, will be presented in this study.

Methods: The study concerned a retrospective review of 594 patients, undergoing a total thyroidectomy for Graves' disease. Read More

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http://dx.doi.org/10.1016/j.jcte.2019.100183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377402PMC
June 2019
11 Reads

Review article: Non-fatal strangulation: Hidden injuries, hidden risks.

Authors:
Julia De Boos

Emerg Med Australas 2019 Jun 19;31(3):302-308. Epub 2019 Feb 19.

Emergency Department, Mount Isa Base Hospital, Mornington, Queensland, Australia.

Non-fatal strangulation (NFS) can be a cause of severe injury. However, the prevalence and rates of injuries from NFS are unknown, as few victims present to medical attention after strangulation. As up to 40% of fatal strangulations have no external signs, and the majority of surviving victims have few or minor injuries, finding those people severely injured remains challenging. Read More

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http://doi.wiley.com/10.1111/1742-6723.13243
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http://dx.doi.org/10.1111/1742-6723.13243DOI Listing
June 2019
10 Reads

First case report of thyroid abscess caused by Helicobacter cinaedi presenting with thyroid storm.

BMC Infect Dis 2019 Feb 15;19(1):166. Epub 2019 Feb 15.

Division of Pulmonary Medicine, Department of Internal Medicine, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, 4-2-22 Nishikicho, Tachikawa, Tokyo, 190-8531, Japan.

Background: Helicobacter cinaedi is a microaerobic Gram-negative spiral-shaped bacterium that causes enteritis, cellulitis, and bacteremia in both immunocompromised and immunocompetent patients. While there have been increasing numbers of reported H. cinaedi infections recently, there has been no thyroid abscess case caused by H. Read More

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http://dx.doi.org/10.1186/s12879-019-3808-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377776PMC
February 2019
8 Reads

Simultaneous presentation of thyroid storm and diabetic ketoacidosis in a previously healthy 21-year-old man.

BMJ Case Rep 2019 Jan 28;12(1). Epub 2019 Jan 28.

Department of Biomedical Sciences, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, Michigan, USA.

A 21-year-old young man with no history of diabetes or thyroid disease presented to the emergency department with simultaneous thyroid storm and diabetic ketoacidosis. Notable findings on admission were a ventricular rate of 235 beats/min, tachypnoea, tremors, polydipsia and a lack of fever. Due to the unusual constellation of symptoms, diagnosis was only possible after initial laboratory results came back. Read More

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http://dx.doi.org/10.1136/bcr-2018-227554DOI Listing
January 2019
8 Reads

A case of Graves' disease developing with exacerbation of sarcoidosis.

Sarcoidosis Vasc Diffuse Lung Dis 2019 1;36(4):318-324. Epub 2019 May 1.

Department of Diagnostic Pathology, Nara Medical University Hospital, Kashiwara, Japan.

A 53-year old female was referred to our hospital with bilateral abnormal shadow in the chest X-ray. Computed tomography revealed multifocal ill-defined densities and thickening of bronchial wall and pulmonary vessels by fine nodules combined with massive enlargement of bilateral mediastinal and hilar lymph nodes. Analyses of bronchoalveolar lavage fluid and transbronchial lung biopsy specimen showed the increase in CD4/CD8 ratio and the presence of non-caseating granulomas, respectively. Read More

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http://dx.doi.org/10.36141/svdld.v36i4.8307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247091PMC

Thyroid storm: a case of haemodynamic failure promptly reversed by aggressive medical therapy with antithyroid agents and steroid pulse.

BMJ Case Rep 2018 Dec 14;11(1). Epub 2018 Dec 14.

Intensive Care Unit, Centro Hospitalar do Médio Tejo EPE, Unidade de Abrantes, Abrantes, Santarém, Portugal.

Hyperthyroidism is a common metabolic disorder, although its presentation as an endocrine emergency called thyroid storm is rare. Here we review a case of a thyroid storm as the initial presentation of thyrotoxicosis, with multiple organ failure and haemodynamic collapse due to low-output cardiac dysfunction. Quick intervention with aggressive antithyroid therapy, including steroid pulse, and supportive intensive care measures led to an outstanding improvement and full recovery. Read More

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http://dx.doi.org/10.1136/bcr-2018-226669DOI Listing
December 2018
14 Reads

Unfavorable Socioeconomic Factors Underlie High Rates of Hospitalization for Complicated Thyrotoxicosis in Some Regions of the United States.

Thyroid 2019 01;29(1):27-35

1 Division of Endocrinology, Department of Internal Medicine, Texas Tech University Health Sciences Center School of Medicine, Lubbock, Texas.

Objective: The authors' institution-a safety net, university, and tertiary-care hospital located in West Texas-has a high number of hospital admissions for complicated thyrotoxicosis. It was hypothesized that unfavorable socioeconomic conditions result in increased risk of poor outcomes in hyperthyroid patients, and increased rates of hospitalization for thyrotoxicosis in West Texas. The primary aim of this study was to identify factors associated with admission for complicated thyrotoxicosis in patients living in the Panhandle and Llano Estacado of Texas. Read More

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https://www.liebertpub.com/doi/10.1089/thy.2018.0353
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http://dx.doi.org/10.1089/thy.2018.0353DOI Listing
January 2019
21 Reads

Diabetic Ketoacidosis Associated with Thyroxine (T₄) Toxicosis and Thyrotoxic Cardiomyopathy.

Medicina (Kaunas) 2018 Nov 26;54(6). Epub 2018 Nov 26.

Department of Internal Medicine, Hospital Regional Lambayeque, Chiclayo, Lambayeque 14012, Peru.

Thyrotoxicosis and diabetic ketoacidosis (DKA) both may present as endocrine emergencies and may have devastating consequences if not diagnosed and managed promptly and effectively. The combination of diabetes mellitus (DM) with thyrotoxicosis is well known, and one condition usually precedes the other. Furthermore, thyrotoxicosis is complicated by some degree of cardiomyopathy in at least 5% de patients; but the coexistence of DKA, thyroxin (T₄) toxicosis, and acute cardiomyopathy is extremely rare. Read More

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http://dx.doi.org/10.3390/medicina54060093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306916PMC
November 2018
5 Reads

Thyroid Storm Induced by Trauma: A Challenging Combination.

Am Surg 2018 Feb;84(2):e44-e46

Division of GI, Tumor, and Endocrine Surgery, Department of Surgery, University of Colorado, Aurora, Colorado, USA.

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February 2018
4 Reads

Acute Thyroid Storm Following Thymectomy: A Surprising Result of Undiagnosed Graves' Disease.

Cureus 2018 Aug 31;10(8):e3239. Epub 2018 Aug 31.

Surgery, University of Texas Medical Branch, Galveston, USA.

Postoperative thyroid storm represents a diagnostic dilemma in patients with overlooked hyperthyroid state undergoing a nonthyroid surgery. We report a 30-year-old female with a history of mixed connective tissue disease who presented with an anterior mediastinal mass and underwent a thoracoscopic resection of the mass. On postoperative day 1, she had an acute change in mental status with fever, tachycardia and hypercapnic respiratory failure requiring intubation and mechanical ventilation. Read More

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http://dx.doi.org/10.7759/cureus.3239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209514PMC
August 2018
39 Reads

National Trends in Incidence, Mortality, and Clinical Outcomes of Patients Hospitalized for Thyrotoxicosis With and Without Thyroid Storm in the United States, 2004-2013.

Thyroid 2019 01 18;29(1):36-43. Epub 2018 Dec 18.

1 Department of Medicine, Division of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, Georgia.

Background: Current evidence on the incidence and outcomes of patients with thyroid storm in the United States is limited to single-center case series. This study determined the national incidence of thyrotoxicosis with and without thyroid storm and clinical outcomes among hospitalized patients during a 10-year period in the United States.

Methods: Retrospective longitudinal analysis was conducted of clinical characteristics, mortality, hospital length of stay, and costs from 2004 to 2013. Read More

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http://dx.doi.org/10.1089/thy.2018.0275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916241PMC
January 2019
25 Reads