- Matthieu Pelletier-Galarneau,
- Patrick Martineau,
- Ran Klein,
- Matthew Henderson,
- Lionel S Zuckier
J Appl Clin Med Phys 2017 Nov 22. Epub 2017 Nov 22.
Division of Nuclear Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada.
Background: Measurement of radioactive iodine uptake (RAIU) is an important aspect of the assessment and treatment of patients with hyperthyroidism. Its uncertainty affects how much of a true change in RAIU can be detected as well as appropriateness of the therapy dosage upon which it is based. In this study, a method of estimating the reproducibility and least significant change (LSC) values for RAIU measurements, and the implications of the values observed are discussed, with emphasis on application to quality assurance initiatives. Read More