- Jason M Springer,
- Vineesh V Raveendran,
- Selina A Gierer,
- Mehrdad Maz,
- Kottarappat N Dileepan
Front Immunol 2017 23;8:990. Epub 2017 Aug 23.
Division of Allergy, Clinical Immunology and Rheumatology, Department of Medicine, University of Kansas Medical Center, Kansas City, KS, United States.
Mast cells are important cells of the immune system. Although traditionally considered as key players in allergic and hypersensitivity reactions, emerging evidence suggests that mast cells have many complex roles in vascular disease. These include regulation of vasodilation, angiogenesis, activation of matrix metalloproteinases, apoptosis of smooth muscle cells, and activation of the renin angiotensin system. Read More