3,182 results match your criteria Hypersensitivity Vasculitis


Obstructive sleep apnoea in patients with fibrotic diffuse parenchymal lung disease-characterization and treatment compliance assessment.

Can J Respir Ther 2018 1;54(2):35-40. Epub 2018 Aug 1.

Pulmonology Department, Centro Hospitalar São João, Oporto, Portugal.

Introduction: Recent studies have reported a high prevalence of obstructive sleep apnoea (OSA) among patients with diffuse parenchymal lung disease (DPLD), mainly idiopathic pulmonary fibrosis (IPF). Effective OSA treatment appears to have a positive impact on morbidity and mortality in these patients. However, poor compliance to positive airway pressure (PAP) treatment in fibrotic DPLD patients has been reported. Read More

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http://dx.doi.org/10.29390/cjrt-2018-005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422053PMC
August 2018
1 Read

The rash with maculopapules and fever in children.

Clin Dermatol 2019 Mar - Apr;37(2):119-128. Epub 2018 Dec 5.

Dermatology Department, University of CT Health Center, Farmington, Connecticut, USA. Electronic address:

Several medical conditions can cause children to present with fever and a maculopapular rash Although some presentations are benign, others may be medical emergencies, which warrant a prompt diagnosis. We review some of the more common causes of fever and maculopapular dermatitirs, rash including infectious processes (roseola; rubeola; rubella; parvovirus B19; hand, foot, and mouth disease; scarlet fever; meningococcemia; Epstein-Barr virus infection), hypersensitivity reactions (exanthematous drug reactions), and vasculitis syndromes (Kawasaki disease). We have included a diagnostic algorithm to facilitate rapid identification of the etiology of the rash and fever. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0738081X183025
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http://dx.doi.org/10.1016/j.clindermatol.2018.12.005DOI Listing
December 2018
3 Reads

Exceptional association of hypocomplementemic urticarial vasculitis syndrome (HUVS) and symptomatic pulmonary histoplasmosis: a case-based literature review.

Clin Rheumatol 2019 Apr 13. Epub 2019 Apr 13.

Departments of Medicine and Rheumatology, MetroHealth Medical Center, Cleveland, OH, USA.

Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare type III hypersensitivity disorder characterized by urticarial vasculitis and prolonged hypocomplementemia. Individuals with HUVS may also have joint involvement, pulmonary manifestations, ocular disease, kidney inflammation, or any other form of organ involvement. Hypocomplementemia, the presence of C1q antibody in the serum, and urticarial vasculitis are the keys to the diagnosis of HUVS. Read More

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http://dx.doi.org/10.1007/s10067-019-04548-8DOI Listing
April 2019
1 Read

Fatal necrotizing esophagitis in a patient with leukocytoclastic cutaneous vasculitis and ankylosing spondylitis.

Autops Case Rep 2019 Apr-Jun;9(2):e2018070. Epub 2019 Mar 22.

Universidade de São Paulo (USP), Hospital Universitário, Internal Medicine Division. São Paulo, SP, Brazil.

Esophageal infection by spp. is a common opportunistic entity in immunocompromised hosts; however, systemic fungal dissemination due to perforation or transmural necrosis, also known as necrotizing esophagitis (NCE), is rare. We report the case of a 61-year-old male patient with diagnosed ankylosing spondylitis, severe arteriosclerosis, and vasculitis under immunosuppressive therapy who presented NCE with fungal and bacterial septicemia diagnosed at autopsy. Read More

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http://www.autopsyandcasereports.org/article/doi/10.4322/acr
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http://dx.doi.org/10.4322/acr.2018.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433139PMC
March 2019
3 Reads

Multiple cutaneous and mucosal lesions in a patient with cocaine-levamisole-induced vasculopathy syndrome.

Proc (Bayl Univ Med Cent) 2019 Jan 27;32(1):93-95. Epub 2018 Dec 27.

Division of Rheumatology, Department of Internal Medicine, Rush University Medical CenterChicagoIllinois.

Levamisole is an adulterant found in nearly 70% of cocaine in the United States. The concomitant use of levamisole and cocaine leads to a distinct clinical syndrome that typically manifests as agranulocytosis, leukocytoclastic vasculitis, and elevated antineutrophil cytoplasmic antibody (ANCA) levels. Systemic involvement has also been rarely reported with this syndrome. Read More

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http://dx.doi.org/10.1080/08998280.2018.1503478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442875PMC
January 2019
2 Reads

Dermatologic Aspects of Systemic Vasculitis.

Neurol Clin 2019 May 16;37(2):465-473. Epub 2019 Mar 16.

Department of Pathology, Division of Dermatology and Dermatopathology, Albany Medical College, 43 New Scotland Avenue, MC-81, Albany, NY 12208, USA.

Systemic and localized vasculitis affects the skin and subcutis, due to large vascular beds and hemodynamic factors, such as stasis in lower extremities, and environmental influences, as occur in cold exposure. Initial cutaneous manifestations of vasculitides include diverse and dynamic patterns of discoloration, swelling, hemorrhage, and necrosis. One-half of affected patients present with localized, self-limited disease to the skin without any known trigger or associated systemic disease, known as idiopathic cutaneous leukocytoclastic vasculitis. Read More

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http://dx.doi.org/10.1016/j.ncl.2019.01.017DOI Listing
May 2019
1 Read

Targetoid Skin Lesions in a Child: Acute Hemorrhagic Oedema of Infancy and Its Differential Diagnosis.

Int J Environ Res Public Health 2019 Mar 6;16(5). Epub 2019 Mar 6.

Pediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, 06129 Perugia, Italy.

Acute hemorrhagic oedema of infancy (AHEI) is a cutaneous leukocytoclastic small-vessel vasculitis presenting with localized purpuric large skin plaques that are frequently associated with fever and oedema. It must be promptly differentiated from a number of diseases with similar dermatologic manifestations with potentially severe clinical courses that require adequate monitoring and prompt therapy to avoid the risk of a negative evolution. A 15-month-old girl with a negative personal medical clinical history was admitted for the sudden appearance of petechiae on the soft palate. Read More

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http://dx.doi.org/10.3390/ijerph16050823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427215PMC
March 2019
2 Reads

Cutaneous Polyarteritis Nodosa Treated with Pentoxifylline and Clobetasol Propionate: A Case Report.

Saudi J Med Med Sci 2018 May-Aug;6(2):104-107. Epub 2018 Apr 16.

Department of Dermatology, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Cutaneous polyarteritis nodosa is a rare type of cutaneous vasculitis. It affects the small- and medium-sized arteries of the dermis and subcutaneous tissue without extracutaneous involvement. The diagnosis is by skin biopsy, and the characteristic finding is a leukocytoclastic vasculitis. Read More

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http://dx.doi.org/10.4103/sjmms.sjmms_148_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196709PMC
April 2018
1 Read

Are there distinct clinical and pathological features distinguishing Idiopathic from Drug-Induced Subacute Cutaneous Lupus Erythematosus? A European retrospective multicenter study.

J Am Acad Dermatol 2019 Feb 11. Epub 2019 Feb 11.

Dermatology - Department Medical Science and Public Health, University of Cagliari, Via Ospedale 54, 09124 Cagliari Italy; European Academy of Dermatology and Venereology (EADV) Task Force of Dermatopathology; SIDEMAST Dermatopathology Study Group of Italian Society of Dermatology.

Background: Clinical and pathological criteria to distinguish drug-induced subacute lupus erythematosus (DI-SCLE) from idiopathic (I-SCLE) are controversial.

Objective: Aim of the survey was a retrospective analysis of a consistent number of iatrogenous and idiopathic SCLE cases, by means of clinical and histopathological investigation.

Methods: Eleven European University Dermatology Units collected all diagnosed cases from January 2000 to December 2016. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.02.009DOI Listing
February 2019
3 Reads
4.449 Impact Factor

Tamoxifen induced non-purpuric cutaneous leukocytoclastic vasculitis.

Breast J 2019 Mar 12;25(2):320-321. Epub 2019 Feb 12.

Department of Oncology, University of Alberta and Cross Cancer Institute, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/tbj.13218DOI Listing
March 2019
1 Read

Azathioprine hypersensitivity syndrome in anti-myeloperoxidase anti-neutrophil cytoplasmic antibody-associated vasculitis.

Clin Kidney J 2019 Feb 23;12(1):89-91. Epub 2018 May 23.

Department of Internal Medicine, Division of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.

Two patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) and rapid onset of high fever, tachycardia and systemic hypotension accompanied by elevated laboratory markers of infection were diagnosed with azathioprine hypersensitivity syndrome only after repeat exposure. Azathioprine hypersensitivity can closely mimic sepsis and/or vasculitis activity and should be considered in AAV, a condition with frequent use of this drug. We discuss the pitfalls in diagnosis and the possible pathophysiologic background. Read More

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http://dx.doi.org/10.1093/ckj/sfy038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366126PMC
February 2019

Hypersensitivity Myocarditis and Necrotizing Coronary Vasculitis by Clomipramine Causing Steroid-Sensitive Cardiogenic Shock.

Circ Cardiovasc Imaging 2019 Feb;12(2):e008736

Department of Cardiovascular, Nephrologic, Anesthesiologic and Geriatric Sciences, La Sapienza University of Rome (A.F., C.C.).

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http://dx.doi.org/10.1161/CIRCIMAGING.118.008736DOI Listing
February 2019
1 Read

Case of both rivaroxaban- and dabigatran-induced leukocytoclastic vasculitis, during management of pulmonary thromboembolism.

Respir Med Case Rep 2019 25;26:219-222. Epub 2019 Jan 25.

Department of Internal Medicine, Inha University College of Medicine, South Korea.

Leukocytoclastic vasculitis is a disorder characterized by neutrophilic inflammation that is predominantly limited to the superficial cutaneous postcapillary venules. This condition may be idiopathic or may have a defined cause. Rivaroxaban and dabigatran have been widely used as warfarin alternatives, because of their efficacy and safety. Read More

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http://dx.doi.org/10.1016/j.rmcr.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356047PMC
January 2019
3 Reads

Cutaneous paraneoplastic syndromes.

Semin Diagn Pathol 2019 Jan 31. Epub 2019 Jan 31.

PRW Laboratories, Charlottesville, VA, United State.

A variety of cutaneous abnormalities can be seen in patients with malignant diseases, some of which are infectious, with others representing direct involvement of the skin by the underlying disorder. Yet another group of lesions can be regarded as associated markers of the malignant process, and, as such, are termed "paraneoplastic." This review considers the latter collection of conditions, grouping them by the generic type of malignancy that is usually linked to the paraneoplasia. Read More

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http://dx.doi.org/10.1053/j.semdp.2019.01.001DOI Listing
January 2019
15 Reads

[Essential mixed cryoglobulinemia type II: case report.]

Rev Fac Cien Med Univ Nac Cordoba 2018 11 13;75(4):292-298. Epub 2018 Nov 13.

.

The cryoglobulinemic syndrome is produced by precipitating immunoglobulins at low temperatures. Its production is associated with several causes, such as lymphoproliferative disorders, chronic infections and autoimmune disorders. However, the etiology is unknow. Read More

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http://dx.doi.org/10.31053/1853.0605.v74.n3.17550DOI Listing
November 2018
3 Reads

Hyperacute Paraplegia and Neurovascular (Immuno Vasculotoxic) Catastrophe of Nicolau Syndrome: Primum Non nocere.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):104-108

Department of Pathology, Kasturba Medical College (Manipal University), Mangalore, Karnataka, India.

A case of Nicolau syndrome (NS) in a 36-year-old adult taking an unusual and devastating hyperacute irreversible paraplegia after an intramuscular injection of benzathine penicillin as a part of routine chemoprophylaxis of her rheumatic heart disease is reported. Although this syndrome is a considerably rare, iatrogenic and underappreciated dermatologic entity, we reiterate in this report, its extracutaneous systemic potential for a catastrophic neurovascular phenomenon and morbidity as well as its possible preventive measures. The apoplectiform onset of T10 flaccid areflexic paraplegia, with the cutaneous hallmark of "embolia cutis medicamentosa" was corroborated by magnetic resonance imaging evidence of centromedullary complete cord involvement from T10 to conus medullaris. Read More

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http://dx.doi.org/10.4103/aian.AIAN_298_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327711PMC
January 2019
3 Reads

Androgen deprivation therapy for prostate cancer and the risk of autoimmune diseases.

Prostate Cancer Prostatic Dis 2019 Jan 28. Epub 2019 Jan 28.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.

Background: Androgen deprivation therapy (ADT) has been a mainstay of treatment for advanced prostate cancer (PCa), but limited studies have been performed to investigate the association between ADT and autoimmune diseases.

Methods: We conducted a population-based nationwide cohort study of 17,168 patients newly diagnosed with PCa between 1996 and 2013 using the National Health Insurance Research Database (NHIRD) of Taiwan. Cox proportional hazards models with 1:1 propensity score-matched analysis were used to investigate the association between ADT use and the risk of autoimmune diseases. Read More

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http://www.nature.com/articles/s41391-019-0130-9
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http://dx.doi.org/10.1038/s41391-019-0130-9DOI Listing
January 2019
19 Reads

Cutaneous leukocytoclastic vasculitis associated with erlotinib treatment: A case report and review of the literature.

Exp Ther Med 2019 Feb 19;17(2):1128-1131. Epub 2018 Nov 19.

CMI Dermamed, 540530 Târgu Mureş, Romania.

Erlotinib is a targeted anticancer therapy used for treating epidermal growth factor receptor (EGFR) mutation positive lung cancer in advanced stage as well as for other malignancies. The most common cutaneous side effect of erlotinib, are well documented; however the number of reports regarding cutaneous leukocytoclastic vasculitis (CLCV) are limited. We report a case, a 58-year-old, 60 kg weight, non-smoking woman suffering of lung adenocarcinoma and brain metastases treated with erlotinib monotherapy with 150 mg/day dose, who presents cutaneous leukocytoclastic vasculitis after 8 months of initiating the treatment. Read More

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http://dx.doi.org/10.3892/etm.2018.6988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327513PMC
February 2019
2 Reads

Rare Association of Leukocytoclastic Vasculitis in Visceral Leishmaniaisis.

Oman Med J 2019 Jan;34(1):66-69

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

A 30-year-old man presented with fever, hepatosplenomegaly, and a rash over his lower limbs (palpable purpura). Evaluation revealed pancytopenia and hypergammaglobulinemia. A subsequent bone marrow examination and serology confirmed visceral leishmaniasis (kala-azar), while the biopsy of skin lesion suggested leukocytoclastic vasculitis. Read More

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http://dx.doi.org/10.5001/omj.2019.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330183PMC
January 2019
2 Reads

Successful treatment of normocomplementemic urticarial vasculitis with omalizumab: A report of three cases and literature review.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Urticarial vasculitis (UV) is a rare form of cutaneous leukocytoclastic vasculitis with persistent urticarial lesions. UV may be severe and refractory to standard treatment including antihistamines, anti-inflammatories, antimalarials, corticosteroids and immunosuppressants. Omalizumab, an anti-IgE antibody, is approved for chronic spontaneous urticaria. Read More

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http://dx.doi.org/10.12932/AP-050918-0402DOI Listing
January 2019
10 Reads

Cutaneous leukocytoclastic vasculitis as the first manifestation of malignant syphilis coinfected with human immunodeficiency virus.

J Cutan Pathol 2019 May 7;46(5):393-395. Epub 2019 Feb 7.

Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China.

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http://dx.doi.org/10.1111/cup.13420DOI Listing
May 2019
4 Reads

Vancomycin-Induced Leukocytoclastic Vasculitis: A Rare Case Report.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618820873. Epub 2018 Dec 21.

St. Joseph Hospital, Bangor, ME, USA.

Vancomycin causes different types of hypersensitivity reactions, ranging from localized skin reactions to generalized cardiovascular collapse. However, cases of vancomycin-induced leukocytoclastic vasculitis are rare. In this article, we present a case where the patient developed palpable purpura on his bilateral lower limbs following treatment with vancomycin. Read More

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http://journals.sagepub.com/doi/10.1177/2324709618820873
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http://dx.doi.org/10.1177/2324709618820873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304699PMC
December 2018
3 Reads

Urticarial vasculitis as an initial manifestation of colonic carcinoma: a case report and review of the literature.

Authors:
A A Younis

Reumatismo 2018 Dec 20;70(4):259-263. Epub 2018 Dec 20.

Rheumatology Department, Faruk Medical City.

Cutaneous vasculitis may behave as a paraneoplastic syndrome. Paraneoplastic vasculitis as a phenomenon of colonic adenocarcinoma has been described in the literature. To the best of my knowledge, this is the first case report of urticarial vasculitis being an initial presentation of signet-ring cell carcinoma of the colon. Read More

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http://dx.doi.org/10.4081/reumatismo.2018.1052DOI Listing
December 2018
2 Reads

Acute hemorrhagic edema of infancy: guide to prevent misdiagnosis.

Cutis 2018 Nov;102(5):359-362

Department of Dermatology, Geisinger Health System, Danville, Pennsylvania, USA.

We report the case of a 10-month-old previously healthy boy who presented with acute rash, edema, and low-grade fever in the setting of recent diarrhea. We differentiate between acute hemorrhagic edema of infancy (AHEI) and Henoch-Schönlein purpura (HSP). Read More

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November 2018
15 Reads

Vasculitis-What Do We Have to Know? A Review of Literature.

Int J Low Extrem Wounds 2018 Dec 3;17(4):218-226. Epub 2018 Dec 3.

1 Women's College Hospital, Toronto, Ontario, Canada.

Cutaneous and other vasculitides are specific inflammations of the blood vessel wall that can take place in any organ system of the body including the skin. Vasculitis has been traditionally divided according to the size of the vessel involved (small, medium, and large). Vasculitis is more of a reaction pattern rather than a specific disease entity. Read More

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http://dx.doi.org/10.1177/1534734618804982DOI Listing
December 2018
2 Reads

Purpuric drug eruption without leukocytoclastic vasculitis associated with vancomycin.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Pediatrics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan.

Vancomycin (VCM) has been reported to elicit adverse cutaneous drug reactions. However, VCM-associated purpuric drug eruption has not been reported yet, except leukocytoclastic vasculitis. A 16-year-old Japanese girl was admitted with a respiratory infection. Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-21051
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http://dx.doi.org/10.12932/AP-210518-0319DOI Listing
October 2018
14 Reads
1.255 Impact Factor

Hypersensitivity reactions to non-vitamin K oral anticoagulants - a review of literature and diagnostic work-up proposal.

Eur Ann Allergy Clin Immunol 2019 Jan 12;51(1):7-14. Epub 2018 Nov 12.

UOC Medicina Interna e Reumatologia, Allergologia, Ospedale Infermi, Rimini, Italy.

Summary: Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly being used in hospital and outpatient settings as safe alternatives to warfarin. Hypersensitivity reactions have been described for NOACs and can be classified according to Gell and Coombs. We reviewed case reports of possible drug hypersensitivity reactions, noticing a predominance of delayed reactions (both mild and severe) and the absence of cross-reactions to warfarin and low molecu-lar weight heparins. Read More

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http://www.eurannallergyimm.com/cont/online-first/642/review
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.80DOI Listing
January 2019
24 Reads

Leukocytoclastic Vasculitis Associated with HHV6-A/ciHHV6-A and HHV6-B Coinfection in an Immunocompetent Woman.

Endocr Metab Immune Disord Drug Targets 2019 ;19(2):221-225

Microbiology and Virology Unit, Policlinico University Hospital of Bari, Italy.

Background And Objective: Leukocytoclastic vasculitis (LCV) is a small vessel vasculitis that can be limited to the skin but may also affect other organs. Often, its cause is unknown. LCV has previously been reported to occur with the reactivation of human herpesvirus 6 (HHV-6). Read More

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http://dx.doi.org/10.2174/1871530318666181106153758DOI Listing
January 2019
4 Reads

Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report.

J Med Case Rep 2018 Oct 31;12(1):320. Epub 2018 Oct 31.

Division of Hematology, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan.

Background: Multiple myeloma is a very heterogeneous disease comprising a number of genetic entities that differ from each other in their evolution, mode of presentation, response to therapy, and prognosis. Due to its more chronic nature and cumulative toxicities that patients develop from multiple lines of treatments, a number of symptoms are associated with multiple myeloma. However, the mechanisms responsible for the relationship between these symptoms and multiple myeloma currently remain unclear. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1857-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208011PMC
October 2018
8 Reads

Palisaded neutrophilic and granulomatous dermatitis associated with systemic lupus erythematosus: possible involvement of CD163 M2 macrophages in two cases, and a review of published works.

Lupus 2018 Dec 30;27(14):2220-2227. Epub 2018 Oct 30.

1 Department of Dermatology, Kansai Medical University, Hirakata, Japan.

Background: Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a commonly occurring condition related to systemic autoimmune disease. It is characterized histopathologically by a distinct pattern of granulomatous inflammation in the presence or absence of leukocytoclastic vasculitis. The properties of granulomatous cells in PNGD are still uncertain. Read More

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http://journals.sagepub.com/doi/10.1177/0961203318809892
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http://dx.doi.org/10.1177/0961203318809892DOI Listing
December 2018
4 Reads

Levamisole-induced vasculopathy with gastric involvement in a cocaine user.

Cutis 2018 Sep;102(3):169;170;175;176

Department of Dermatology, Vanderbilt University, Nashville, Tennessee, USA.

Reports of levamisole-induced vasculopathy (LIV) secondary to use of levamisole-contaminated cocaine largely have been limited to the skin. We report the case of a 35-year-old woman with painful purpuric lesions affecting the cheeks, nose, ears, arms, and legs of several days' duration. She recently had used crack cocaine. Read More

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September 2018
15 Reads

Azathioprine Hypersensitivity Syndrome in a Cohort of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Patients.

J Allergy Clin Immunol Pract 2019 Mar 24;7(3):1004-1009. Epub 2018 Oct 24.

Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

Background: Azathioprine hypersensitivity syndrome is a rare complication of azathioprine therapy. Its symptoms resemble infection or relapse of inflammatory disease, hindering correct diagnosis. Current literature is limited to sporadic case reports and reviews. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183067
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http://dx.doi.org/10.1016/j.jaip.2018.10.018DOI Listing
March 2019
21 Reads

[Vasculitides and eosinophilic pulmonary diseases].

Z Rheumatol 2018 Dec;77(10):907-922

Abt. für Rheumatologie, Immunologie und Rehabilitation, Kantonsspital St. Gallen, St. Gallen, Schweiz.

Eosinophilic granulocytes form peripheral effector cells controlled by Th2 lymphocytes, which cause local cell, tissue, and functional disorders of infiltrated organs via the release of cytotoxic basic proteins and oxygen radicals. Diseases associated with eosinophilia include systemic and organ-related forms. The lungs are involved in eosinophilic granulomatosis with polyangiitis (EGPA, formerly known as Churg-Strauss syndrome), acute and chronic eosinophilic pneumonia, as well as in an organ manifestation in hypereosinophilic syndrome and certain parasitic diseases. Read More

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http://link.springer.com/10.1007/s00393-018-0561-z
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http://dx.doi.org/10.1007/s00393-018-0561-zDOI Listing
December 2018
19 Reads

Vasculitis of small and large vessels, a casual association?

Rev Assoc Med Bras (1992) 2018 Jul;64(7):590-594

Internal Medicine Department - III, District Hospital of Santarem, Portugal.

The authors report a case of a 69-year-old man with idiopathic leukocytoclastic cutaneous vasculitis. For three years, the lesions recurred with progressive worsening and were associated with systemic manifestations of low-grade fever, weight loss and raised inflammatory markers. The patient latter presented a 6th cranial nerve involvement, raising the concern of a possible systemic vasculitis, which was latter evidenced by the development of deep vein thrombosis and angina pectoris. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.64.07.590DOI Listing
July 2018
13 Reads

Erythema elevatum diutinum a rare and poorly understood cutaneous vasculitis: A single institution experience.

J Cutan Pathol 2019 Feb 3;46(2):97-101. Epub 2018 Dec 3.

Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.

Background: Erythema elevatum diutinum (EED) is a rare vasculitis with variable clinical presentation which diagnosis can be challenging. Herein we want to describe the clinicopathological spectrum of findings in five cases of EED.

Methods: We retrospectively analyzed five cases in a single institution collected over a period of 27 years. Read More

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http://doi.wiley.com/10.1111/cup.13378
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http://dx.doi.org/10.1111/cup.13378DOI Listing
February 2019
16 Reads

Patient-reported outcomes in urticarial vasculitis treated with omalizumab: case report.

BMC Dermatol 2018 10 25;18(1). Epub 2018 Oct 25.

Respiralab, Respiralab Research Group, Guayaquil, Ecuador.

Background: Despite the current knowledge of UV, there is a lack of consensus among diagnostic criteria and management. In general, antihistamine therapy is regularly used for the symptomatic management of pruritus but does not control inflammation or alter the course of the disease. Monoclonal antibodies such as omalizumab (anti-IgE) have been proposed as a potential treatment for urticarial vasculitis. Read More

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https://bmcdermatol.biomedcentral.com/articles/10.1186/s1289
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http://dx.doi.org/10.1186/s12895-018-0077-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203196PMC
October 2018
19 Reads

Use of QuantiFERON-TB Gold to determine the aetiology of idiopathic erythema induratum: A case report.

SAGE Open Med Case Rep 2018 10;6:2050313X18804076. Epub 2018 Oct 10.

Toronto Regional Dermatology and Wound Healing Clinic, Mississauga, ON, Canada.

Although rare, erythema induratum is the most common entity presenting as lobular panniculitis with vasculitis. It is usually caused by a hypersensitivity reaction to , although other aetiologies have been reported. We present a case of a 73-year-old male with multiple recurring tender erythematous nodules on the backs of both calves and shins. Read More

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http://journals.sagepub.com/doi/10.1177/2050313X18804076
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http://dx.doi.org/10.1177/2050313X18804076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180361PMC
October 2018
13 Reads

Antineutrophil cytoplasmic antibodies negative levamisole-induced leukocytoclastic vasculitis: a presumed case and literature review.

Int J Dermatol 2018 Dec 25;57(12):1411-1416. Epub 2018 Sep 25.

Department of Dermatology, University of Texas Medical Branch, Galveston, TX, USA.

Levamisole-contaminated cocaine toxicity is a serious emerging public health concern, and providers should be aware of its presentation and management. Most cases of levamisole-induced vasculitis/vasculopathy (LIV) are associated with high antineutrophil cytoplasmic antibodies (ANCA). We describe a unique case of a cocaine user who presented with an acute purpuric eruption and negative ANCA laboratory findings. Read More

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http://dx.doi.org/10.1111/ijd.14249DOI Listing
December 2018
12 Reads

A case of Graves' disease associated with membranoproliferative glomerulonephritis and leukocytoclastic vasculitis.

J Pediatr Endocrinol Metab 2018 Oct;31(10):1165-1168

Ghent University, Department of Pediatrics and Medical Genetics, Ghent, Belgium.

Background The association of hyperthyroidism with renal disease is very rare and the importance of timely clinical recognition cannot be overemphasized. Case presentation An 11-year-old girl presented with gastrointestinal symptoms while hypertension, edema and abdominal pain were noticed on clinical examination. Laboratory investigation revealed: hemoglobin 9. Read More

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http://dx.doi.org/10.1515/jpem-2018-0186DOI Listing
October 2018
7 Reads

Annular Lesions: Diagnosis and Treatment.

Am Fam Physician 2018 Sep;98(5):283-291

Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Annular lesions can present in a variety of diseases. Knowledge of the physical appearance and history of presentation of these skin findings can help in the diagnosis. A pruritic, annular, erythematous patch that grows centrifugally should prompt evaluation for tinea corporis. Read More

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September 2018
9 Reads

[Sweet syndrome in a 5-year-old girl].

Arch Argent Pediatr 2018 Oct;116(5):e671-e674

Servicio de Pediatría del Instituto Roosevelt, Universidad del Rosario.

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is an infrequent dermatological disorder in pediatrics. Clinically it is characterized by the development of papular and/or nodular lesions of a reddish-violet coloration with local hypersensitivity. We report the case of a 5-year-old female who consulted 1 month after the appearance of the lesion in the nasal arch. Read More

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http://dx.doi.org/10.5546/aap.2018.e671DOI Listing
October 2018
1 Read

[Drug-induced vasculitis].

Therapie 2018 Jul 24. Epub 2018 Jul 24.

Département de pharmacologie, faculté de médecine de Sousse, université de Sousse, avenue Md Karoui, 4002 Sousse, Tunisie.

Introduction: Drug-induced vasculitis is reported in almost 10-20 % of vasculitis. Several drugs may be incriminated in their occurrence. Our study aimed to study the epidemiological, clinical, histopathological and evolutionary characteristics of drug-indced vasculitis from a series of cases and to specify the different drugs involved. Read More

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http://dx.doi.org/10.1016/j.therap.2018.07.005DOI Listing
July 2018
47 Reads

Severe/uncontrolled asthma and overall survival in atopic patients with eosinophilic granulomatosis with polyangiitis.

Respir Med 2018 09 24;142:66-72. Epub 2018 Jul 24.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. Electronic address:

Background: Although asthma, rhinitis/rhinosinusitis and peripheral eosinophilia are present in virtually all patients with eosinophilic granulomatosis with polyangiitis (EGPA), the role of atopy in these patients is not well defined.

Objective: To clarify the role of atopy in patients affected with EGPA.

Methods: Clinical, laboratory and standard spirometry data have been abstracted from medical records. Read More

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http://dx.doi.org/10.1016/j.rmed.2018.07.017DOI Listing
September 2018
8 Reads

HIV-associated erythema elevatum diutinum: a case report and review of a clinically distinct variant.

Dermatol Online J 2018 05 15;24(5). Epub 2018 May 15.

Medstar Georgetown University Hospital, Washington, District of Columbia.

A 24-year-old man with untreated human immunodeficiency virus (HIV) infection consulted our outreach clinic owing to the development of numerous asymptomatic nodules on his palms and fingers. Histopathologic evaluation revealed leukocytoclastic vasculitis and prominent fibrosis with a neutrophilic infiltrate consistent with erythema elevatum diutinum (EED). We referred the patient for initiation of antiretroviral therapy and started him on dapsone. Read More

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May 2018
13 Reads

[Vasculitides and eosinophilic pulmonary diseases].

Internist (Berl) 2018 09;59(9):898-910

Abt. für Rheumatologie, Immunologie und Rehabilitation, Kantonsspital St. Gallen, St. Gallen, Schweiz.

Eosinophilic granulocytes form peripheral effector cells controlled by Th2 lymphocytes, which cause local cell, tissue, and functional disorders of infiltrated organs via the release of cytotoxic basic proteins and oxygen radicals. Diseases associated with eosinophilia include systemic and organ-related forms. The lungs are involved in eosinophilic granulomatosis with polyangiitis (EGPA, formerly known as Churg-Strauss syndrome), acute and chronic eosinophilic pneumonia, as well as in an organ manifestation in hypereosinophilic syndrome and certain parasitic diseases. Read More

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http://link.springer.com/10.1007/s00108-018-0479-1
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http://dx.doi.org/10.1007/s00108-018-0479-1DOI Listing
September 2018
26 Reads

Cutaneous Vasculitis in Cogan's Syndrome: A Report of Two Cases Associated with Chlamydia Infection.

J Nippon Med Sch 2018 ;85(3):172-177

Department of Dermatology, Nippon Medical School.

Cogan's syndrome (CS) is defined by the combination of hearing loss, vertigo, and ocular inflammation of uncertain cause, and can be associated with variable vessel vasculitis. Vasculitic manifestations may include arteritis (affecting large, medium or small arteries), aortitis, and aortic and mitral valvulitis. Cutaneous manifestations including erythema, papules, subcutaneous nodules, and purpura sometimes occur; however, to date, only six cases have been histologically confirmed to have genuine vasculitis. Read More

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http://dx.doi.org/10.1272/jnms.JNMS.2018_85-25DOI Listing
October 2018
18 Reads

A Unique Case Report on Hypersensitivity Vasculitis as an Allergic Reaction to the Herpes Zoster Vaccine.

Vasc Endovascular Surg 2019 Jan 20;53(1):75-78. Epub 2018 Aug 20.

1 Department of Vascular Medicine, Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.

Hypersensitivity vasculitis (HV) or leukocytoclastic vasculitis is a rare small-vessel vasculitis that may occur as a manifestation of the body's extreme allergic reaction to a drug, infection, or other foreign substance. Characterized by the presence of inflammatory neutrophils in vessel walls, HV results in inflammation and damage to blood vessels, primarily in the skin. Histologically, when neutrophils undergo leukocytoclasia and release nuclear debris into the vasculature, vascular damage manifests as palpable purpura. Read More

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http://dx.doi.org/10.1177/1538574418794079DOI Listing
January 2019
14 Reads

Cutaneous and Gastrointestinal Leukocytoclastic Vasculitis Induced by Palbociclib in a Metastatic Breast Cancer Patient: A Case Report.

Clin Breast Cancer 2018 10 16;18(5):e755-e758. Epub 2018 Aug 16.

Medical Oncology Department, Institut de Cancérologie de l'Ouest, Centre Paul Papin, Angers, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15268209183031
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http://dx.doi.org/10.1016/j.clbc.2018.07.006DOI Listing
October 2018
27 Reads

Anti-PD1 therapy-associated cutaneous leucocytoclastic vasculitis: A case series.

Eur J Intern Med 2018 11 31;57:e11-e12. Epub 2018 Jul 31.

Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1016/j.ejim.2018.07.023DOI Listing
November 2018
1 Read