3,167 results match your criteria Hypersensitivity Vasculitis


Are there distinct clinical and pathological features distinguishing Idiopathic from Drug-Induced Subacute Cutaneous Lupus Erythematosus? A European retrospective multicenter study.

J Am Acad Dermatol 2019 Feb 11. Epub 2019 Feb 11.

Dermatology - Department Medical Science and Public Health, University of Cagliari, Via Ospedale 54, 09124 Cagliari Italy; European Academy of Dermatology and Venereology (EADV) Task Force of Dermatopathology; SIDEMAST Dermatopathology Study Group of Italian Society of Dermatology.

Background: Clinical and pathological criteria to distinguish drug-induced subacute lupus erythematosus (DI-SCLE) from idiopathic (I-SCLE) are controversial.

Objective: Aim of the survey was a retrospective analysis of a consistent number of iatrogenous and idiopathic SCLE cases, by means of clinical and histopathological investigation.

Methods: Eleven European University Dermatology Units collected all diagnosed cases from January 2000 to December 2016. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.02.009DOI Listing
February 2019

Tamoxifen induced non-purpuric cutaneous leukocytoclastic vasculitis.

Breast J 2019 Feb 12. Epub 2019 Feb 12.

Department of Oncology, University of Alberta and Cross Cancer Institute, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/tbj.13218DOI Listing
February 2019

Azathioprine hypersensitivity syndrome in anti-myeloperoxidase anti-neutrophil cytoplasmic antibody-associated vasculitis.

Clin Kidney J 2019 Feb 23;12(1):89-91. Epub 2018 May 23.

Department of Internal Medicine, Division of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.

Two patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) and rapid onset of high fever, tachycardia and systemic hypotension accompanied by elevated laboratory markers of infection were diagnosed with azathioprine hypersensitivity syndrome only after repeat exposure. Azathioprine hypersensitivity can closely mimic sepsis and/or vasculitis activity and should be considered in AAV, a condition with frequent use of this drug. We discuss the pitfalls in diagnosis and the possible pathophysiologic background. Read More

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http://dx.doi.org/10.1093/ckj/sfy038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366126PMC
February 2019

Hypersensitivity Myocarditis and Necrotizing Coronary Vasculitis by Clomipramine Causing Steroid-Sensitive Cardiogenic Shock.

Circ Cardiovasc Imaging 2019 Feb;12(2):e008736

Department of Cardiovascular, Nephrologic, Anesthesiologic and Geriatric Sciences, La Sapienza University of Rome (A.F., C.C.).

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http://dx.doi.org/10.1161/CIRCIMAGING.118.008736DOI Listing
February 2019
1 Read

Case of both rivaroxaban- and dabigatran-induced leukocytoclastic vasculitis, during management of pulmonary thromboembolism.

Respir Med Case Rep 2019 25;26:219-222. Epub 2019 Jan 25.

Department of Internal Medicine, Inha University College of Medicine, South Korea.

Leukocytoclastic vasculitis is a disorder characterized by neutrophilic inflammation that is predominantly limited to the superficial cutaneous postcapillary venules. This condition may be idiopathic or may have a defined cause. Rivaroxaban and dabigatran have been widely used as warfarin alternatives, because of their efficacy and safety. Read More

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http://dx.doi.org/10.1016/j.rmcr.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356047PMC
January 2019
1 Read

Cutaneous paraneoplastic syndromes.

Semin Diagn Pathol 2019 Jan 31. Epub 2019 Jan 31.

PRW Laboratories, Charlottesville, VA, United State.

A variety of cutaneous abnormalities can be seen in patients with malignant diseases, some of which are infectious, with others representing direct involvement of the skin by the underlying disorder. Yet another group of lesions can be regarded as associated markers of the malignant process, and, as such, are termed "paraneoplastic." This review considers the latter collection of conditions, grouping them by the generic type of malignancy that is usually linked to the paraneoplasia. Read More

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http://dx.doi.org/10.1053/j.semdp.2019.01.001DOI Listing
January 2019
1 Read

[Essential mixed cryoglobulinemia type II: case report.]

Rev Fac Cien Med Univ Nac Cordoba 2018 11 13;75(4):292-298. Epub 2018 Nov 13.

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The cryoglobulinemic syndrome is produced by precipitating immunoglobulins at low temperatures. Its production is associated with several causes, such as lymphoproliferative disorders, chronic infections and autoimmune disorders. However, the etiology is unknow. Read More

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http://dx.doi.org/10.31053/1853.0605.v74.n3.17550DOI Listing
November 2018
1 Read

Hyperacute Paraplegia and Neurovascular (Immuno Vasculotoxic) Catastrophe of Nicolau Syndrome: Primum Non nocere.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):104-108

Department of Pathology, Kasturba Medical College (Manipal University), Mangalore, Karnataka, India.

A case of Nicolau syndrome (NS) in a 36-year-old adult taking an unusual and devastating hyperacute irreversible paraplegia after an intramuscular injection of benzathine penicillin as a part of routine chemoprophylaxis of her rheumatic heart disease is reported. Although this syndrome is a considerably rare, iatrogenic and underappreciated dermatologic entity, we reiterate in this report, its extracutaneous systemic potential for a catastrophic neurovascular phenomenon and morbidity as well as its possible preventive measures. The apoplectiform onset of T10 flaccid areflexic paraplegia, with the cutaneous hallmark of "embolia cutis medicamentosa" was corroborated by magnetic resonance imaging evidence of centromedullary complete cord involvement from T10 to conus medullaris. Read More

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http://dx.doi.org/10.4103/aian.AIAN_298_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327711PMC
January 2019
2 Reads

Androgen deprivation therapy for prostate cancer and the risk of autoimmune diseases.

Prostate Cancer Prostatic Dis 2019 Jan 28. Epub 2019 Jan 28.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.

Background: Androgen deprivation therapy (ADT) has been a mainstay of treatment for advanced prostate cancer (PCa), but limited studies have been performed to investigate the association between ADT and autoimmune diseases.

Methods: We conducted a population-based nationwide cohort study of 17,168 patients newly diagnosed with PCa between 1996 and 2013 using the National Health Insurance Research Database (NHIRD) of Taiwan. Cox proportional hazards models with 1:1 propensity score-matched analysis were used to investigate the association between ADT use and the risk of autoimmune diseases. Read More

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http://www.nature.com/articles/s41391-019-0130-9
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http://dx.doi.org/10.1038/s41391-019-0130-9DOI Listing
January 2019
5 Reads

Cutaneous leukocytoclastic vasculitis associated with erlotinib treatment: A case report and review of the literature.

Exp Ther Med 2019 Feb 19;17(2):1128-1131. Epub 2018 Nov 19.

CMI Dermamed, 540530 Târgu Mureş, Romania.

Erlotinib is a targeted anticancer therapy used for treating epidermal growth factor receptor (EGFR) mutation positive lung cancer in advanced stage as well as for other malignancies. The most common cutaneous side effect of erlotinib, are well documented; however the number of reports regarding cutaneous leukocytoclastic vasculitis (CLCV) are limited. We report a case, a 58-year-old, 60 kg weight, non-smoking woman suffering of lung adenocarcinoma and brain metastases treated with erlotinib monotherapy with 150 mg/day dose, who presents cutaneous leukocytoclastic vasculitis after 8 months of initiating the treatment. Read More

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http://dx.doi.org/10.3892/etm.2018.6988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327513PMC
February 2019
1 Read

Rare Association of Leukocytoclastic Vasculitis in Visceral Leishmaniaisis.

Oman Med J 2019 Jan;34(1):66-69

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

A 30-year-old man presented with fever, hepatosplenomegaly, and a rash over his lower limbs (palpable purpura). Evaluation revealed pancytopenia and hypergammaglobulinemia. A subsequent bone marrow examination and serology confirmed visceral leishmaniasis (kala-azar), while the biopsy of skin lesion suggested leukocytoclastic vasculitis. Read More

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http://dx.doi.org/10.5001/omj.2019.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330183PMC
January 2019
1 Read

Successful treatment of normocomplementemic urticarial vasculitis with omalizumab: A report of three cases and literature review.

Asian Pac J Allergy Immunol 2019 Jan 13. Epub 2019 Jan 13.

Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Urticarial vasculitis (UV) is a rare form of cutaneous leukocytoclastic vasculitis with persistent urticarial lesions. UV may be severe and refractory to standard treatment including antihistamines, anti-inflammatories, antimalarials, corticosteroids and immunosuppressants. Omalizumab, an anti-IgE antibody, is approved for chronic spontaneous urticaria. Read More

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http://dx.doi.org/10.12932/AP-050918-0402DOI Listing
January 2019
5 Reads

Cutaneous leukocytoclastic vasculitis as the first manifestation of malignant syphilis coinfected with human immunodeficiency virus.

J Cutan Pathol 2019 Jan 10. Epub 2019 Jan 10.

Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China.

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http://dx.doi.org/10.1111/cup.13420DOI Listing
January 2019
2 Reads

Vancomycin-Induced Leukocytoclastic Vasculitis: A Rare Case Report.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618820873. Epub 2018 Dec 21.

St. Joseph Hospital, Bangor, ME, USA.

Vancomycin causes different types of hypersensitivity reactions, ranging from localized skin reactions to generalized cardiovascular collapse. However, cases of vancomycin-induced leukocytoclastic vasculitis are rare. In this article, we present a case where the patient developed palpable purpura on his bilateral lower limbs following treatment with vancomycin. Read More

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http://journals.sagepub.com/doi/10.1177/2324709618820873
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http://dx.doi.org/10.1177/2324709618820873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304699PMC
December 2018
2 Reads

Urticarial vasculitis as an initial manifestation of colonic carcinoma: a case report and review of the literature.

Authors:
A A Younis

Reumatismo 2018 Dec 20;70(4):259-263. Epub 2018 Dec 20.

Rheumatology Department, Faruk Medical City.

Cutaneous vasculitis may behave as a paraneoplastic syndrome. Paraneoplastic vasculitis as a phenomenon of colonic adenocarcinoma has been described in the literature. To the best of my knowledge, this is the first case report of urticarial vasculitis being an initial presentation of signet-ring cell carcinoma of the colon. Read More

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http://dx.doi.org/10.4081/reumatismo.2018.1052DOI Listing
December 2018
1 Read

Vasculitis-What Do We Have to Know? A Review of Literature.

Int J Low Extrem Wounds 2018 Dec 3;17(4):218-226. Epub 2018 Dec 3.

1 Women's College Hospital, Toronto, Ontario, Canada.

Cutaneous and other vasculitides are specific inflammations of the blood vessel wall that can take place in any organ system of the body including the skin. Vasculitis has been traditionally divided according to the size of the vessel involved (small, medium, and large). Vasculitis is more of a reaction pattern rather than a specific disease entity. Read More

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http://dx.doi.org/10.1177/1534734618804982DOI Listing
December 2018
1 Read

Purpuric drug eruption without leukocytoclastic vasculitis associated with vancomycin.

Asian Pac J Allergy Immunol 2018 Oct 15. Epub 2018 Oct 15.

Department of Pediatrics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan.

Vancomycin (VCM) has been reported to elicit adverse cutaneous drug reactions. However, VCM-associated purpuric drug eruption has not been reported yet, except leukocytoclastic vasculitis. A 16-year-old Japanese girl was admitted with a respiratory infection. Read More

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http://apjai-journal.org/wp-content/uploads/2018/10/AP-21051
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http://dx.doi.org/10.12932/AP-210518-0319DOI Listing
October 2018
9 Reads
1.255 Impact Factor

Hypersensitivity reactions to non-vitamin K oral anticoagulants - a review of literature and diagnostic work-up proposal.

Eur Ann Allergy Clin Immunol 2019 Jan 12;51(1):7-14. Epub 2018 Nov 12.

UOC Medicina Interna e Reumatologia, Allergologia, Ospedale Infermi, Rimini, Italy.

Summary: Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly being used in hospital and outpatient settings as safe alternatives to warfarin. Hypersensitivity reactions have been described for NOACs and can be classified according to Gell and Coombs. We reviewed case reports of possible drug hypersensitivity reactions, noticing a predominance of delayed reactions (both mild and severe) and the absence of cross-reactions to warfarin and low molecu-lar weight heparins. Read More

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http://www.eurannallergyimm.com/cont/online-first/642/review
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.80DOI Listing
January 2019
19 Reads

Leukocytoclastic Vasculitis Associated with HHV6-A/ciHHV6-A and HHV6-B Coinfection in an Immunocompetent Woman. LCV with HHV6-A/ciHHV6-A and HHV6-B Coinfection.

Endocr Metab Immune Disord Drug Targets 2018 Nov 6. Epub 2018 Nov 6.

Microbiology and Virology Unit, Policlinico University Hospital of Bari. Italy.

Background And Objective: Leukocytoclastic vasculitis (LCV) is a small vessel vasculitis that can be limited to the skin but may also affect other organs. Often, its cause is unknown. LCV has previously been reported to occur with the reactivation of human herpesvirus 6 (HHV-6). Read More

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http://dx.doi.org/10.2174/1871530318666181106153758DOI Listing
November 2018
3 Reads

Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report.

J Med Case Rep 2018 Oct 31;12(1):320. Epub 2018 Oct 31.

Division of Hematology, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan.

Background: Multiple myeloma is a very heterogeneous disease comprising a number of genetic entities that differ from each other in their evolution, mode of presentation, response to therapy, and prognosis. Due to its more chronic nature and cumulative toxicities that patients develop from multiple lines of treatments, a number of symptoms are associated with multiple myeloma. However, the mechanisms responsible for the relationship between these symptoms and multiple myeloma currently remain unclear. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1857-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208011PMC
October 2018
4 Reads

Palisaded neutrophilic and granulomatous dermatitis associated with systemic lupus erythematosus: possible involvement of CD163 M2 macrophages in two cases, and a review of published works.

Lupus 2018 Dec 30;27(14):2220-2227. Epub 2018 Oct 30.

1 Department of Dermatology, Kansai Medical University, Hirakata, Japan.

Background: Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a commonly occurring condition related to systemic autoimmune disease. It is characterized histopathologically by a distinct pattern of granulomatous inflammation in the presence or absence of leukocytoclastic vasculitis. The properties of granulomatous cells in PNGD are still uncertain. Read More

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http://journals.sagepub.com/doi/10.1177/0961203318809892
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http://dx.doi.org/10.1177/0961203318809892DOI Listing
December 2018
3 Reads

Levamisole-induced vasculopathy with gastric involvement in a cocaine user.

Cutis 2018 Sep;102(3):169;170;175;176

Department of Dermatology, Vanderbilt University, Nashville, Tennessee, USA.

Reports of levamisole-induced vasculopathy (LIV) secondary to use of levamisole-contaminated cocaine largely have been limited to the skin. We report the case of a 35-year-old woman with painful purpuric lesions affecting the cheeks, nose, ears, arms, and legs of several days' duration. She recently had used crack cocaine. Read More

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September 2018
10 Reads

Azathioprine Hypersensitivity Syndrome in a Cohort of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Patients.

J Allergy Clin Immunol Pract 2018 Oct 24. Epub 2018 Oct 24.

Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

Background: Azathioprine hypersensitivity syndrome is a rare complication of azathioprine therapy. Its symptoms resemble infection or relapse of inflammatory disease, hindering correct diagnosis. Current literature is limited to sporadic case reports and reviews. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183067
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http://dx.doi.org/10.1016/j.jaip.2018.10.018DOI Listing
October 2018
15 Reads

[Vasculitides and eosinophilic pulmonary diseases].

Z Rheumatol 2018 Dec;77(10):907-922

Abt. für Rheumatologie, Immunologie und Rehabilitation, Kantonsspital St. Gallen, St. Gallen, Schweiz.

Eosinophilic granulocytes form peripheral effector cells controlled by Th2 lymphocytes, which cause local cell, tissue, and functional disorders of infiltrated organs via the release of cytotoxic basic proteins and oxygen radicals. Diseases associated with eosinophilia include systemic and organ-related forms. The lungs are involved in eosinophilic granulomatosis with polyangiitis (EGPA, formerly known as Churg-Strauss syndrome), acute and chronic eosinophilic pneumonia, as well as in an organ manifestation in hypereosinophilic syndrome and certain parasitic diseases. Read More

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http://link.springer.com/10.1007/s00393-018-0561-z
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http://dx.doi.org/10.1007/s00393-018-0561-zDOI Listing
December 2018
14 Reads

Vasculitis of small and large vessels, a casual association?

Rev Assoc Med Bras (1992) 2018 Jul;64(7):590-594

Internal Medicine Department - III, District Hospital of Santarem, Portugal.

The authors report a case of a 69-year-old man with idiopathic leukocytoclastic cutaneous vasculitis. For three years, the lesions recurred with progressive worsening and were associated with systemic manifestations of low-grade fever, weight loss and raised inflammatory markers. The patient latter presented a 6th cranial nerve involvement, raising the concern of a possible systemic vasculitis, which was latter evidenced by the development of deep vein thrombosis and angina pectoris. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1806-9282.64.07.590DOI Listing
July 2018
7 Reads

Erythema elevatum diutinum a rare and poorly understood cutaneous vasculitis: A single institution experience.

J Cutan Pathol 2019 Feb 3;46(2):97-101. Epub 2018 Dec 3.

Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.

Background: Erythema elevatum diutinum (EED) is a rare vasculitis with variable clinical presentation which diagnosis can be challenging. Herein we want to describe the clinicopathological spectrum of findings in five cases of EED.

Methods: We retrospectively analyzed five cases in a single institution collected over a period of 27 years. Read More

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http://doi.wiley.com/10.1111/cup.13378
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http://dx.doi.org/10.1111/cup.13378DOI Listing
February 2019
10 Reads

Patient-reported outcomes in urticarial vasculitis treated with omalizumab: case report.

BMC Dermatol 2018 10 25;18(1). Epub 2018 Oct 25.

Respiralab, Respiralab Research Group, Guayaquil, Ecuador.

Background: Despite the current knowledge of UV, there is a lack of consensus among diagnostic criteria and management. In general, antihistamine therapy is regularly used for the symptomatic management of pruritus but does not control inflammation or alter the course of the disease. Monoclonal antibodies such as omalizumab (anti-IgE) have been proposed as a potential treatment for urticarial vasculitis. Read More

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https://bmcdermatol.biomedcentral.com/articles/10.1186/s1289
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http://dx.doi.org/10.1186/s12895-018-0077-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203196PMC
October 2018
14 Reads

Use of QuantiFERON-TB Gold to determine the aetiology of idiopathic erythema induratum: A case report.

SAGE Open Med Case Rep 2018 10;6:2050313X18804076. Epub 2018 Oct 10.

Toronto Regional Dermatology and Wound Healing Clinic, Mississauga, ON, Canada.

Although rare, erythema induratum is the most common entity presenting as lobular panniculitis with vasculitis. It is usually caused by a hypersensitivity reaction to , although other aetiologies have been reported. We present a case of a 73-year-old male with multiple recurring tender erythematous nodules on the backs of both calves and shins. Read More

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http://journals.sagepub.com/doi/10.1177/2050313X18804076
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http://dx.doi.org/10.1177/2050313X18804076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180361PMC
October 2018
7 Reads

A case of Graves' disease associated with membranoproliferative glomerulonephritis and leukocytoclastic vasculitis.

J Pediatr Endocrinol Metab 2018 Oct;31(10):1165-1168

Ghent University, Department of Pediatrics and Medical Genetics, Ghent, Belgium.

Background The association of hyperthyroidism with renal disease is very rare and the importance of timely clinical recognition cannot be overemphasized. Case presentation An 11-year-old girl presented with gastrointestinal symptoms while hypertension, edema and abdominal pain were noticed on clinical examination. Laboratory investigation revealed: hemoglobin 9. Read More

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http://dx.doi.org/10.1515/jpem-2018-0186DOI Listing
October 2018
4 Reads

Annular Lesions: Diagnosis and Treatment.

Am Fam Physician 2018 Sep;98(5):283-291

Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Annular lesions can present in a variety of diseases. Knowledge of the physical appearance and history of presentation of these skin findings can help in the diagnosis. A pruritic, annular, erythematous patch that grows centrifugally should prompt evaluation for tinea corporis. Read More

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September 2018
9 Reads

[Sweet syndrome in a 5-year-old girl].

Arch Argent Pediatr 2018 Oct;116(5):e671-e674

Servicio de Pediatría del Instituto Roosevelt, Universidad del Rosario.

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is an infrequent dermatological disorder in pediatrics. Clinically it is characterized by the development of papular and/or nodular lesions of a reddish-violet coloration with local hypersensitivity. We report the case of a 5-year-old female who consulted 1 month after the appearance of the lesion in the nasal arch. Read More

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http://dx.doi.org/10.5546/aap.2018.e671DOI Listing
October 2018

[Drug-induced vasculitis].

Therapie 2018 Jul 24. Epub 2018 Jul 24.

Département de pharmacologie, faculté de médecine de Sousse, université de Sousse, avenue Md Karoui, 4002 Sousse, Tunisie.

Introduction: Drug-induced vasculitis is reported in almost 10-20 % of vasculitis. Several drugs may be incriminated in their occurrence. Our study aimed to study the epidemiological, clinical, histopathological and evolutionary characteristics of drug-indced vasculitis from a series of cases and to specify the different drugs involved. Read More

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http://dx.doi.org/10.1016/j.therap.2018.07.005DOI Listing
July 2018
36 Reads

Severe/uncontrolled asthma and overall survival in atopic patients with eosinophilic granulomatosis with polyangiitis.

Respir Med 2018 09 24;142:66-72. Epub 2018 Jul 24.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. Electronic address:

Background: Although asthma, rhinitis/rhinosinusitis and peripheral eosinophilia are present in virtually all patients with eosinophilic granulomatosis with polyangiitis (EGPA), the role of atopy in these patients is not well defined.

Objective: To clarify the role of atopy in patients affected with EGPA.

Methods: Clinical, laboratory and standard spirometry data have been abstracted from medical records. Read More

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http://dx.doi.org/10.1016/j.rmed.2018.07.017DOI Listing
September 2018
6 Reads

HIV-associated erythema elevatum diutinum: a case report and review of a clinically distinct variant.

Dermatol Online J 2018 05 15;24(5). Epub 2018 May 15.

Medstar Georgetown University Hospital, Washington, District of Columbia.

A 24-year-old man with untreated human immunodeficiency virus (HIV) infection consulted our outreach clinic owing to the development of numerous asymptomatic nodules on his palms and fingers. Histopathologic evaluation revealed leukocytoclastic vasculitis and prominent fibrosis with a neutrophilic infiltrate consistent with erythema elevatum diutinum (EED). We referred the patient for initiation of antiretroviral therapy and started him on dapsone. Read More

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May 2018
9 Reads

[Vasculitides and eosinophilic pulmonary diseases].

Internist (Berl) 2018 09;59(9):898-910

Abt. für Rheumatologie, Immunologie und Rehabilitation, Kantonsspital St. Gallen, St. Gallen, Schweiz.

Eosinophilic granulocytes form peripheral effector cells controlled by Th2 lymphocytes, which cause local cell, tissue, and functional disorders of infiltrated organs via the release of cytotoxic basic proteins and oxygen radicals. Diseases associated with eosinophilia include systemic and organ-related forms. The lungs are involved in eosinophilic granulomatosis with polyangiitis (EGPA, formerly known as Churg-Strauss syndrome), acute and chronic eosinophilic pneumonia, as well as in an organ manifestation in hypereosinophilic syndrome and certain parasitic diseases. Read More

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http://link.springer.com/10.1007/s00108-018-0479-1
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http://dx.doi.org/10.1007/s00108-018-0479-1DOI Listing
September 2018
20 Reads

Cutaneous Vasculitis in Cogan's Syndrome: A Report of Two Cases Associated with Chlamydia Infection.

J Nippon Med Sch 2018 ;85(3):172-177

Department of Dermatology, Nippon Medical School.

Cogan's syndrome (CS) is defined by the combination of hearing loss, vertigo, and ocular inflammation of uncertain cause, and can be associated with variable vessel vasculitis. Vasculitic manifestations may include arteritis (affecting large, medium or small arteries), aortitis, and aortic and mitral valvulitis. Cutaneous manifestations including erythema, papules, subcutaneous nodules, and purpura sometimes occur; however, to date, only six cases have been histologically confirmed to have genuine vasculitis. Read More

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http://dx.doi.org/10.1272/jnms.JNMS.2018_85-25DOI Listing
October 2018
14 Reads

A Unique Case Report on Hypersensitivity Vasculitis as an Allergic Reaction to the Herpes Zoster Vaccine.

Vasc Endovascular Surg 2018 Aug 20:1538574418794079. Epub 2018 Aug 20.

1 Department of Vascular Medicine, Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.

Hypersensitivity vasculitis (HV) or leukocytoclastic vasculitis is a rare small-vessel vasculitis that may occur as a manifestation of the body's extreme allergic reaction to a drug, infection, or other foreign substance. Characterized by the presence of inflammatory neutrophils in vessel walls, HV results in inflammation and damage to blood vessels, primarily in the skin. Histologically, when neutrophils undergo leukocytoclasia and release nuclear debris into the vasculature, vascular damage manifests as palpable purpura. Read More

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http://dx.doi.org/10.1177/1538574418794079DOI Listing
August 2018
13 Reads

Cutaneous and Gastrointestinal Leukocytoclastic Vasculitis Induced by Palbociclib in a Metastatic Breast Cancer Patient: A Case Report.

Clin Breast Cancer 2018 Oct 16;18(5):e755-e758. Epub 2018 Aug 16.

Medical Oncology Department, Institut de Cancérologie de l'Ouest, Centre Paul Papin, Angers, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15268209183031
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http://dx.doi.org/10.1016/j.clbc.2018.07.006DOI Listing
October 2018
19 Reads

Erythema elevatum diutinum: a case report and review of literature.

Int J Dermatol 2018 Aug 3. Epub 2018 Aug 3.

The Kimberly and Eric J. Waldman Department of Dermatology and Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Erythema elevatum diutinum (EED) is a rare cutaneous leukocytoclastic vasculitis thought to be related to increased levels of circulating antibodies. It has been shown to be associated with HIV infection, tuberculosis, as well as various autoimmune diseases. A retrospective review of all cases of EED indexed in PubMed between 1990 and 2014 was performed. Read More

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http://dx.doi.org/10.1111/ijd.14169DOI Listing
August 2018
2 Reads

Case 2: Hemolacria, Hematochezia, and Hematuria in an 11-month-old Boy.

Pediatr Rev 2018 Aug;39(8):418-420

Department of Pediatrics, Cohen Children's Medical Center at Northwell Health, New Hyde Park, NY.

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http://dx.doi.org/10.1542/pir.2016-0155DOI Listing
August 2018
2 Reads

Erythema elevatum diutinum.

An Bras Dermatol 2018 Jul-Aug;93(4):614-615

Service of Dermatology, Hospital Guilherme Álvaro, Centro Universitário Lusíada, Santos (SP), Brazil.

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http://dx.doi.org/10.1590/abd1806-4841.20187470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063113PMC
August 2018
6 Reads

Unusual presentation of erythema elevatum diutinum with underlying hepatitis B infection.

Cutis 2018 Jun;101(6):462-465

Ohio State University Medical Center, Columbus, USA.

Erythema elevatum diutinum (EED) is a rare, chronic, cutaneous small vessel vasculitis of unclear pathogenesis. Classically, lesions present as symmetric red to purple plaques, papules, and nodules overlying joints. First-line therapy is dapsone. Read More

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June 2018
3 Reads

Paraneoplastic cutaneous small-vessel vasculitis as a presentation of recurrent metastatic breast cancer.

JAAD Case Rep 2018 Jun 7;4(5):477-479. Epub 2018 May 7.

Division of Dermatology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.jdcr.2017.11.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031593PMC
June 2018
2 Reads

Delayed leucoencephalopathy after coil embolisation of unruptured cerebral aneurysm.

BMJ Case Rep 2018 Jun 23;2018. Epub 2018 Jun 23.

Department of Comprehensive Strokology, Fujita Health University School of Medicine, Toyoake, Japan.

A 56-year-old right-handed woman was successfully treated by coil embolisation for a large unruptured paraclinoid aneurysm of the left internal carotid artery. Though she was discharged on day 3 after the intervention with uneventful clinical course, she was rehospitalised for continuous headache and right upper limb weakness 2 weeks after the treatment. Subsequent progression of cognitive dysfunction and right hemiparesis were observed. Read More

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http://dx.doi.org/10.1136/bcr-2018-224569DOI Listing
June 2018
3 Reads

Cutaneous and Mucosal Manifestations Associated with Celiac Disease.

Nutrients 2018 Jun 21;10(7). Epub 2018 Jun 21.

Dermatology Unit, Hospital Universitario Central de Asturias (HUCA), Avda. de Roma s/n, 33011 Oviedo, Asturias, Spain.

Celiac disease (CD) is an immune-mediated, gluten-induced enteropathy that affects predisposed individuals of all ages. Many patients with CD do not report gastrointestinal symptoms making it difficult to reach an early diagnosis. On the other hand, CD is related to a wide spectrum of extra-intestinal manifestations, with dermatitis herpetiformis (DH) being the best characterized. Read More

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http://dx.doi.org/10.3390/nu10070800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073559PMC
June 2018
3 Reads

Hemostasis in Allergy.

Semin Thromb Hemost 2018 Oct 19;44(7):669-675. Epub 2018 Jun 19.

Division of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Technion Faculty of Medicine, Haifa, Israel.

The involvement of the hemostatic system in immune-mediated inflammation is widely reported. Many coagulation factors play a role in the pathogenesis of autoimmune diseases, such as systemic vasculitis and systemic lupus erythematosus. Hemostatic disorders are also involved in asthma and chronic spontaneous urticaria (CSU). Read More

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http://dx.doi.org/10.1055/s-0038-1648232DOI Listing
October 2018
19 Reads

IgA nephropathy with leucocytoclastic vasculitis.

J Int Med Res 2018 Jul 10;46(7):3009-3014. Epub 2018 Jun 10.

1 Department of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Leucocytoclastic vasculitis is a rare type of allergic disease caused by immune complexes. IgA nephropathy is a glomerulopathy characterized by recurrent episodes of gross haematuria or microscopic haematuria and IgA deposition in the glomerular mesangial region. IgA nephropathy complicating leucocytoclastic vasculitis is rare documented. Read More

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http://dx.doi.org/10.1177/0300060518775814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124258PMC
July 2018
1 Read

Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?

Acta Dermatovenerol Croat 2018 Apr;26(1):61-63

Benigno Monteagudo-Sánchez, MD, Hospital Arquitecto Marcide, Avenida Residencia SN , 15405 Ferrol (A Coruńa), A Coruńa, Spain;

Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). Read More

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April 2018
20 Reads

Hypocomplementemic urticarial vasculitis occurring in a patient with relapsing polychondritis.

Int J Dermatol 2018 11 20;57(11):1363-1364. Epub 2018 May 20.

University of Tunis El Manar, Department of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia.

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http://dx.doi.org/10.1111/ijd.14051DOI Listing
November 2018
9 Reads