Acute kidney injury in a postpartum woman with paroxysmal nocturnal hemoglobinuria: A case report and literature review.
- Masatoshi Nishimoto,
- Masaru Matsui,
- Hideo Tsushima,
- Kaori Tanabe,
- Miho Tagawa,
- Ken-Ich Samejima,
- Yasuhiro Akai,
- Yoshihiko Saito
Hemodial Int 2017 Aug 10. Epub 2017 Aug 10.
First Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.
Paroxysmal nocturnal hemoglobinuria is a rare clonal hematopoietic stem cell disorder characterized by intravascular hemolysis, hemoglobinuria, and inflammatory thrombotic state. Intravascular hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) can lead to acute and chronic renal injury through hemoglobin-mediated toxicity. A 32-year-old pregnant woman with myelodysplastic syndrome was admitted to our hospital with severe preeclampsia. Read More