126 results match your criteria Hyperkeratosis of the Nipple and Areola


Costello syndrome with special cutaneous manifestations and HRAS G12D mutation: A case report and literature review.

Mol Genet Genomic Med 2021 May 1:e1690. Epub 2021 May 1.

Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Background: Costello syndrome (CS, OMIM 218040) is a rare congenital disorder caused by mutations in HRAS. Previous studies reported that approximately 80% of patients with CS share the same pathogenic variant in HRAS gene in c.34G> A (p. Read More

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Spontaneous regression of long-standing bilateral nevoid hyperkeratosis of the nipple and areola in a young female: A case report.

J Dermatol 2021 Apr 18;48(4):e188-e189. Epub 2021 Feb 18.

Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.

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Bilateral nipple neoformations.

JAAD Case Rep 2021 Feb 24;8:86-88. Epub 2020 Nov 24.

Hospital General "Dr. Manuel Gea González", Mexico City, Mexico.

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February 2021

Clinical and macroscopic morphological features of canine tungiasis.

Parasitol Res 2021 Mar 21;120(3):807-818. Epub 2021 Jan 21.

Programa de Pós-Graduação em Ciência Animal, Departamento de Ciências Agrárias e Ambientais, Universidade Estadual de Santa Cruz - UESC, Campus Soane Nazaré de Andrade, Rodovia Jorge Amado, Km 16, Bairro Salobrinho, CEP, Ilheus, BA, 45662-900, Brazil.

Tungiasis is a public health problem in endemic resource-poor communities, where dogs are important reservoirs of Tunga spp., contributing significantly to the process of transmission of this zoonosis. In order to optimize the diagnosis of canine tungiasis, macroscopic morphological characteristics and clinical signs of the lesions were investigated, based on the inspection of 40 dogs infested by T. Read More

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Candida albicans Mastitis in Breastfeeding Woman: An Under Recognized Diagnosis.

Cureus 2020 Dec 11;12(12):e12026. Epub 2020 Dec 11.

Biology, University Djilali Liabes, Sidi Bel Abbès, DZA.

Breastfeeding has been demonstrated to have many benefits for both mother and child. The diagnosis and management of Candida in the breastfeeding dyad are difficult because diagnosis is most often based on subjective signs and symptoms. Few studies have attempted to confirm the diagnosis with biological tests. Read More

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December 2020

Size of supernumerary teats in sheep correlates with complexity of the anatomy and microenvironment.

J Anat 2020 05 2;236(5):954-962. Epub 2020 Jan 2.

Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.

Supernumerary nipples or teats (polythelia) are congenital accessory structures that may develop at any location along the milk line and have been implicated in the pathogenesis of mastitis. We describe the anatomy and histology of 27 spontaneously occurring supernumerary teats from 16 sheep, delineating two groups of teats - simple and anatomically complex - according to the complexity of the anatomy and microenvironment. Anatomically complex supernumerary teats exhibited significantly increased length and barrel diameter compared with simple supernumerary teats. Read More

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Eczematous, Pruritic, Brownish Plaque of the Nipple and Areola: A Quiz.

Acta Derm Venereol 2019 Dec;99(13):1317-1318

Unit of Dermatology, Department of Medicine - DIMED, University of Padova, Via Gallucci 4, IT-35121 Padova, Italy.

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December 2019

Nevoid hyperkeratosis of male breast: Successful treatment with minocycline.

Dermatol Ther 2019 09 21;32(5):e13019. Epub 2019 Jul 21.

Department of Histopathology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Nevoid hyperkeratosis of the nipple and/or areola (NHNA) is an uncommon disease with no definite etiology. NHNA of the male breast is rare in clinical practice. Despite being a benign disease, it is distressing for patients and therapeutically challenging for clinicians. Read More

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September 2019

Erratum: "Crusted nipple and areola: a new aetiology of secondary hyperkeratosis of the nipple and areola".

Authors:

Indian J Dermatol Venereol Leprol 2019 May-Jun;85(3):349

[This corrects the article DOI: 10.4103/ijdvl.IJDVL_399_17]. Read More

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Focal nevoid hyperkeratosis of the nipple in a prepubertal girl.

Pediatr Dermatol 2019 Mar 17;36(2):247-248. Epub 2019 Feb 17.

Department of Dermatology, Hospital Infantil Niño Jesús, Madrid, Spain.

Nevoid hyperkeratosis (NH) of the nipple and areola is an extremely uncommon condition in prepubertal children. We report on a prepubertal girl with NH and provide dermoscopic findings that helped to make the diagnosis. Read More

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Hyperkeratosis of the nipple and areola: a histopathologic pitfall.

J Dtsch Dermatol Ges 2018 Nov 8;16(11):1368-1370. Epub 2018 Oct 8.

Department of Dermatology, University Hospital Regensburg, Germany.

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November 2018

Treatment of nevoid hyperkeratosis of the areola and nipple with topical tacalcitol: A case report.

Dermatol Ther 2018 Jul 6;31(4):e12602. Epub 2018 Apr 6.

Department of Medical, Surgical and Neurological Science, Dermatology Section, University of Siena, S. Maria alle Scotte Hospital, Siena, Italy.

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Dermoscopic assessment of skin toxicities in patients with melanoma during treatment with vemurafenib.

Postepy Dermatol Alergol 2018 Feb 20;35(1):39-46. Epub 2018 Feb 20.

Department of Bone Marrow Transplantation and Onco-Hematology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Poland.

Introduction: The use of vemurafenib in melanoma has improved the survival of patients; however, it is associated with skin toxicities.

Aim: To assess skin toxicities by dermoscopy in patients treated with vemurafenib.

Material And Methods: Eight patients with BRAF V600 mutation positive metastatic melanoma were examined dermoscopically during vemurafenib treatment. Read More

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February 2018

Crusted nipple and areola: A new aetiology of secondary hyperkeratosis of the nipple and areola.

Indian J Dermatol Venereol Leprol 2019 Mar-Apr;85(2):169-170

Department of Dermatology, Faculty of Medicine, Northern Borders University, Arar, Kingdom of Saudi Arabia.

Hyperkeratosis of the nipple and areola is a rare condition first described by Tauber in 1923. Less than 100 cases have been reported in the literature. Hyperkeratosis of the nipple and areola presents as hyperkeratotic, hyperpigmented plaques on the nipple and areola. Read More

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Bilateral hyperkeratosis of the nipples and areolae with linear nevus: a rare case report and review of the literature.

Postgrad Med 2018 Apr 5;130(3):361-364. Epub 2018 Mar 5.

a Beijing Friendship Hospital , Capital Medical University , Beijing , China.

Hyperkeratosis of the nipple and areola is an uncommon dermatosis without well-defined etiology, which occurs mostly in young women and may only be a cosmetic problem. In 1938, Levy-Frankel classified this disease into three variants; type I involves hyperkeratosis with an epidermal nevus, and has rarely been reported. We report a case of a 23-year-old woman with long-term bilateral pigmentation and thickening of the nipples and areolae, accompanied with dark brown, flat lesions with a linear distribution on her left forearm. Read More

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[Hyperkeratotic lesion of the nipple and areola].

Presse Med 2017 Jun 25;46(6 Pt 1):626-628. Epub 2017 May 25.

CHU Ibn Sina, université Mohammed V, faculté de médecine et de pharmacie, dermatologie-vénérologie, Rabat, Maroc.

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Painful nipple hyperkeratosis secondary to vemurafenib.

Dermatol Ther 2017 May 17;30(3). Epub 2017 Feb 17.

Department of Dermatology, Baylor Scott & White Health, Texas A&M Health Science Center College of Medicine, Temple, Texas, 76508.

Vemurafenib is a selected BRAF kinase inhibitor approved for treating metastatic or unresectable melanoma, which has numerous cutaneous side effects unfortunately, including three previously reported cases of asymptomatic areola and/or nipple hyperkeratosis. We present the first case of painful bilateral nipple hyperkeratosis secondary to vemurafenib in an 84-year-old woman. She was successfully treated with tretinoin 0. Read More

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Nevoid hyperkeratosis of the nipple mimicking a pigmented basal cell carcinoma.

JAAD Case Rep 2016 Nov 7;2(6):500-501. Epub 2016 Dec 7.

Department of Clinical Medicine and Surgery, Section of Dermatology, University Federico II, Naples, Italy.

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November 2016

Radical treatment of extensive nevoid hyperkeratosis of the areola and breast with surgical excision after mild response to topical agents: A case report.

Int J Surg Case Rep 2016 22;28:117-120. Epub 2016 Sep 22.

Clinic of Plastic and Reconstructive Surgery, Department of Neurosciences, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.

Introduction: Nevoid hyperkeratosis of the nipple and/or areola (NHNA) is a benign lesion with a female predominance and an aesthetically disturbing appearance. Spontaneous remission is not reported and medical treatments proposed so far have shown variable results.

Presentation Of Case: We describe a rare case of an extensive variant of NHNA covering almost the entire breasts' surface. Read More

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September 2016

Radiofrequency ablation of bilateral nevoid hyperkeratosis of nipple and areola.

Authors:
Anupama Singh

Indian J Dermatol Venereol Leprol 2016 Nov-Dec;82(6):730-732

Department of Skin and V.D., Patna Medical College, Patna, Bihar, India.

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Asymptomatic Hyperpigmented Lesions on the Areolas of a Pediatric Patient.

Actas Dermosifiliogr 2017 05 18;108(4):368. Epub 2016 Jun 18.

Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, España.

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Nevoid hyperkeratosis of the nipple and the areola.

Dermatol Online J 2016 Feb 17;22(2). Epub 2016 Feb 17.

Complejo Hospitalario Torrecardenas, Almeria.

A 25-year-old woman presented to our dermatology unit with progressive diffuse thickening of the both areolas. A skin biopsy was taken from the right areola showing irregular filiform acanthosis with elongation and anastomosis of rete ridges, irregular orthokeratotic hyperkeratosis, pseudocyst formation, and hyperpigmentation of the basal layer. The cause of nevoid hyperkeratosis of the nipple and areola is unknown. Read More

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February 2016

Naevoid hyperkeratosis of the nipple/areola with mycosis fungoides-like changes.

Pathology 2016 Jun 29;48(4):390-3. Epub 2016 Apr 29.

Department of Anatomical Pathology, PathWest, QEII Medical Centre, Perth, Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Perth, WA, Australia. Electronic address:

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The Dilemma of Coexisting Nevoid Hyperkeratosis of the Nipple and Areola in Mycosis Fungoides: A Report of Three Cases.

Dermatopathology (Basel) 2015 Jul-Dec;2(3):61-6. Epub 2015 Nov 17.

Departments of Dermatology and Venereology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.

Nevoid hyperkeratosis of the nipple and areola (NHNA) is a rare clinicopathological entity showing persistent and strictly localized hyperkeratotic lesions of the nipple, areola or both with unknown etiopathogenesis. A similar clinical appearance may also be seen in different diseases with specific histopathological features. There are a few anecdotal reports on the association of NHNA with mycosis fungoides (MF), but they do not describe a uniform condition. Read More

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Successful Breastfeeding Outcome of a Woman with a Nevus of the Nipple: A Case Study.

J Hum Lact 2016 May 21;32(2):361-3. Epub 2016 Mar 21.

Austin Lactation Associates, Manchaca, TX, USA

Unusual conditions of the nipple and breast may interfere with breastfeeding. Nevi of the nipple are rare, and breastfeeding outcomes of women with this condition have only been briefly reported in the literature. This case describes the proactive lactation management and successful breastfeeding outcome of a woman with a large, roughly textured nevus located on her right nipple and areola. Read More

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Pigmented lesion of the nipple - a clinicopathological challenge.

Dermatol Online J 2016 Oct 15;22(10). Epub 2016 Oct 15.

Serviço de Dermatologia e Venereologia, Centro Hospitalar de São João EPE, Porto, Portugal.

Differential diagnoses of pigmented lesions of the nipple include melanocytic nevus, melanosis of the nipple, seborrheic keratosis, pigmented basal cell carcinoma, melanoma and Paget disease. The histologic exam with appropriate immunohistochemistry is a fundamental tool to achieve a correct diagnosis. We present a patient with a pigmented lesion of her right nipple revealing mammary Paget disease and elucidate diagnostic obstacles and prognostic importance of early breast cancer detection. Read More

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October 2016

Dark Brown Plaques and Patches on the Breast and Areola in a 14-Year-Old Female. Nevoid hyperkeratosis of the areola and breast.

Am J Dermatopathol 2015 Aug;37(8):621-2, 659

*Section of Dermatopathology, Department of Dermatology, Boston University School of Medicine, Boston, MA; †Department of Dermatology, Boston University, Boston, MA; and ‡Department of Dermatology, Boston University School of Medicine, Boston, MA.

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Mycosis fungoides mimicking nevoid hyperkeratosis of the nipple and areola in an adolescent.

Turk J Pediatr 2014 Sep-Oct;56(5):565-7

Department of Dermatology, Yıldırım Beyazıt University Faculty of Medicine, Ankara, Turkey; Clinic of Dermatology, Ankara Numune Training and Research Hospital, Ankara, Turkey.

Mycosis fungoides is one of the great imitators in dermatology; it can mimic many dermatoses. Nevoid hyperkeratosis of the nipple and areola is a rare idiopathic disease with typical clinical features of verrucous thickening and brownish discoloration of the nipple, areola or both. Here, a 16-year-old male patient with mycosis fungoides mimicking nevoid hyperkeratosis of the nipple and areola has been reported. Read More

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Vemurafenib-induced hyperkeratosis of the areola treated with topical adapelene.

Clin Exp Dermatol 2016 Mar 22;41(2):148-51. Epub 2015 Feb 22.

Dorset County Hospital, Dorchester, UK.

We present a rare condition, hyperkeratosis of the areola, induced by vemurafenib. Only a few papers have described an association of BRAF inhibitors with hyperkeratosis of the areola and/or nipple. Vemurafenib is a selective BRAF inhibitor used in patients with unresectable or metastatic melanoma who are positive for the V600 mutation. Read More

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