Search our Database of Scientific Publications and Authors

I’m looking for a

    4273 results match your criteria Hyperhidrosis

    1 OF 86

    Thoracic sympathectomy for hyperhidrosis: from surgical indications to clinical results.
    J Thorac Dis 2017 Apr;9(Suppl 3):S178-S192
    Thoracic Surgery Department, Hospital Federal do Andaraí, Rio de Janeiro, Brazil.
    Sympathectomy and its variations have been performed in thoracic surgery for more than 100 years. However, its indications have undergone profound modifications in this period. Likewise, since then the surgical technique has also evolved dramatically up to the minimally invasive techniques worldwide accessible in present days. Read More

    Comparison of T2 and T3 sympathectomy for compensatory sweating on palmar hyperhidrosis.
    Medicine (Baltimore) 2017 Apr;96(16):e6697
    Department of Thoracic Surgery, Karadeniz Technical University Medical School, Trabzon, Turkey.
    Background: An otherwise successfully performed endoscopic thoracic sympathectomy (ETS) to treat palmar hyperhidrosis (PH) often has a serious side effect: compensatory sweating (CS). This side effect occurs in other parts of the body to a disturbing extent. The objective of this study is to determine whether there is a relationship between the level of ETS performed on patients with PH, and the occurrence and severity of postoperational CS. Read More

    Eccrine Nevus Presenting with Umbilical Discharge: A Case Report and Review of the Literature.
    Case Rep Dermatol Med 2017 21;2017:9761843. Epub 2017 Mar 21.
    Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Eccrine nevus is a rare skin lesion with protean manifestations like hyperhidrosis, discolored nodules, papules, and so forth, which has been reported in various anatomic parts of the body including the forearm, leg, thigh, back, and coccyx. Our patient was a 26-year-old male, who presented with increasing colorless and odorless episodic umbilical discharge. First impression for the patient was an umbilical sinus and the patient underwent surgery. Read More

    Confirmatory factor analysis of the Sleep Disturbance Scale for Children (SDSC) in a clinical sample of children and adolescents.
    J Sleep Res 2017 Apr 12. Epub 2017 Apr 12.
    School of Psychological Science, University of Western Australia, Crawley, WA, Australia.
    The Sleep Disturbance Scale for Children was developed as a parent-report measure to screen for sleep disturbances within the preceding 6 months. Notably, the scale was developed using a sample of typically developing children and children with sleep disorders. The aim of this study was to factor analyse the Sleep Disturbance Scale for Children using a clinical sample of children with a range of neuropsychological conditions and co-morbidities, and determine whether the original six-factor structure was retained. Read More

    Optimal targeting of sympathetic chain levels for treatment of palmar hyperhidrosis: an updated systematic review.
    Surg Endosc 2017 Apr 7. Epub 2017 Apr 7.
    Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jie Fang Avenue, Wuhan, 430030, Hubei, China.
    Background: Palmar hyperhidrosis involves excessive sweating of the palms, with no known etiology. Endoscopic thoracic sympathectomy (ETS) is a safe and effective treatment for palmar hyperhidrosis, but compensatory hyperhidrosis is a common complication after ETS, leading to reduced patient satisfaction and postoperative quality of life. However, the appropriate level of the sympathetic chain to target with ETS to achieve maximum efficacy and reduce the risk of compensatory hyperhidrosis (CH) is controversial. Read More

    New Uses of AbobotulinumtoxinA in Aesthetics.
    Aesthet Surg J 2017 May;37(suppl_1):S45-S58
    Dr Schlessinger is a dermatologist and cosmetic surgeon in private practice in Omaha, NE. Dr Gilbert is a dermatologist in private practice in Brooklyn, NY. Dr Cohen is a dermatologist in private practice in Greenwood Village, CO. Dr Kaufman is dermatologist in private practice in Miami, FL.
    BotulinumtoxinA (BoNT-A) is now widely established for the main approved indication of reducing glabellar lines, and is also widely used off-label to improve the appearance of wrinkles and lines in other parts of the face. The number of aesthetic procedures continues to increase as the patient population becomes more diverse, in particular with increasing numbers of people of color and men. Further developments in treatment may continue to expand the audience for BoNT-A by making procedures more comfortable and by delivering a more natural, less static appearance. Read More

    Percutaneous CT-Guided Sympathicolysis with Radiofrequency for the Treatment of Palmar Hyperhidrosis.
    J Vasc Interv Radiol 2017 Mar 30. Epub 2017 Mar 30.
    Radiology Service, Clínica Universidad de Navarra, Avenida Pío XII, 36, C.P. 31008, Pamplona, Spain.
    Purpose: To evaluate the benefits of computed tomography (CT)-guided percutaneous sympathicolysis with radiofrequency in patients with primary palmar hyperhidrosis (PPHH) in terms of safety, patient satisfaction, and short- and long-term efficacy.

    Materials And Methods: A total of 139 procedures in 108 patients (mean age, 29.89 y ± 10. Read More

    Occupational mercury vapour poisoning with a respiratory failure, pneumomediastinum and severe quadriparesis.
    SAGE Open Med Case Rep 2017 23;5:2050313X17695472. Epub 2017 Feb 23.
    Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Wroclaw, Poland.
    Objectives: Despite restrictions, mercury continues to pose a health concern. Mercury has the ability to deposit in most parts of the body and can cause a wide range of unspecific symptoms leading to diagnostic mistakes.

    Methods And Results: We report the case of severe mercury vapour poisoning after occupational exposure in a chloralkali plant worker that resulted in life-threatening respiratory failure, pneumomediastinum and quadriparesis. Read More

    The PARP inhibitor veliparib can be safely added to bendamustine and rituximab and has preliminary evidence of activity in B-cell lymphoma.
    Clin Cancer Res 2017 Mar 17. Epub 2017 Mar 17.
    Medicine - Lymphoma Service, Memorial Sloan-Kettering Cancer Center.
    Purpose: The PARP inhibitor veliparib enhances the cytotoxicity of alkylating agents. This phase 1 study evaluated veliparib with the bifunctional alkylator bendamustine (VB) in patients with relapsed/refractory lymphoma, multiple myeloma, and solid malignancies, with a cohort expansion of VB with rituximab (VBR) in patients with B-cell lymphomas.

    Experimental Design: This dose-escalation study evaluated safety, pharmacokinetics and preliminary efficacy of veliparib (20-400 mg BID, days 1-7 of 28-day cycle) and bendamustine (70 and 90 mg/m2 IV, days 1 and 2). Read More

    Randomized, Placebo- and Active-Controlled Crossover Study of the Safety and Efficacy of THVD-102, a Fixed-dose Combination of Oxybutynin and Pilocarpine, in Subjects With Primary Focal Hyperhidrosis.
    J Drugs Dermatol 2017 Feb;16(2):127-132
    Background: While muscarinic antagonists (anticholinergics) have shown efficacy in treating primary focal hyperhidrosis (PFH), side effects - most commonly dry mouth - are intolerable for most patients. THVD-102, a fixed-dose combination product has been developed combining oxybutynin, a muscarinic antagonist, and pilocarpine, a muscarinic agonist. The pilocarpine is at a dose level and release profile optimized to correct salivary flow impaired by oxybutynin yet not interfere with the therapeutic muscarinic antagonist effect of oxybutynin upon the sweat glands. Read More

    Efficacy and safety of escitalopram in treatment of severe depression in Chinese population.
    Metab Brain Dis 2017 Mar 15. Epub 2017 Mar 15.
    Xi'an Janssen Pharmaceutical Ltd, Beijing, China.
    Severe depression accounts for one-third of depressed patients. Increasing severity of depression usually hinders patients from achieving remission. This study evaluated the efficacy and safety of escitalopram in acute-phase treatment of severe major depressive disorder (MDD). Read More

    Pourfour du Petit Syndrome Associated With Right Eye Pressure.
    Headache 2017 Mar 13. Epub 2017 Mar 13.
    Garibay is a medical student-so just medical student, Baylor College of Medicine, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.
    Pourfour du Petit (PDP) syndrome is a rare disorder characterized by ipsilateral mydriasis, eyelid retraction, and hemifacial hyperhidrosis caused by hyperactivity of the ipsilateral oculosympathetic pathway. A case is presented of PDP syndrome associated with likely ipsilateral occipital neuralgia. We review the causes and co-morbidities and the clinical features of PDP. Read More

    Microwave Treatment for Axillary Hyperhidrosis and Bromhidrosis.
    Actas Dermosifiliogr 2017 Mar 8. Epub 2017 Mar 8.
    Clínica Ruber y Clínica Dermatológica Internacional, Madrid, España.
    Axillary hyperhidrosis (AH) and bromhidrosis are common causes of consultation in dermatology. Currently, the most widely prescribed treatment for AH is botulinum toxin, a very effective but temporary option; it is totally ineffective in bromhidrosis. Sympathectomy is an increasingly infrequent choice of treatment due to the high incidence of compensatory hyperhidrosis. Read More

    R3 versus R4 Thoracoscopic Sympathectomy for Severe Palmar Hyperhidrosis.
    Thorac Cardiovasc Surg 2017 Mar 10. Epub 2017 Mar 10.
    Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, JiangXi, China.
    Background Thoracoscopic sympathectomy (TS) was the preferred surgical treatment for palmar hyperhidrosis (PH), but postoperative complications such as compensatory sweating (CS) were common. This study was projected to compare R3 versus R4 TS for treating severe PH. Methods From April 2009 and March 2015, 106 consecutive patients with severe PH underwent bilateral R3 (n = 62) or R4 (n = 44) TS at The Second Affiliated Hospital of Nanchang University. Read More

    Influence of Body Mass Index on Compensatory Sweating in Patients after Thoracic Sympathectomy due to Palmar Hyperhidrosis.
    Thorac Cardiovasc Surg 2017 Mar 10. Epub 2017 Mar 10.
    Department of General, Endocrine and Transplant Surgery, Gdanski Uniwersytet Medyczny, Ringgold Standard Institution, Gdansk, Poland.
    Background Thoracic sympathectomy (TS) is one of the most effective methods of treatment of primary hyperhidrosis. One of the side effects of this procedure is compensatory sweating (CS). Objective The aim of our study was to evaluate the influence of body mass index (BMI) on CS in patients after TS due to palmar hyperhidrosis. Read More

    A systematic review of microwave-based therapy for axillary hyperhidrosis.
    J Cosmet Laser Ther 2017 Mar 10:1-8. Epub 2017 Mar 10.
    b Department of Dermatology , Shuang Ho Hospital, Taipei Medical University , Taipei , Taiwan.
    Objective: To systematically analyse the literature on the use of the microwave-based device for subdermal thermolysis of the axilla and its efficacy for the treatment of axillary hyperhidrosis.

    Materials And Methods: A systematic review was conducted using PubMed, Embase, SCOPUS and Cochrane databases on 2 June 2016. The inclusion criteria including: (1) studies with human subjects, (2) full-text articles published in English, (3) a microwave-based device used to treat axillary hyperhidrosis and (4) trials that precisely evaluated axillary hyperhidrosis. Read More

    A systematic review and meta-analysis of T2, T3 or T4, to evaluate the best denervation level for palmar hyperhidrosis.
    Sci Rep 2017 Dec 9;7(1):129. Epub 2017 Mar 9.
    Department of Cardiothoracic surgery, The second affiliated hospital of Nanchang University, Nanchang, China.
    We systematically reviewed and compared the clinical outcomes of thoracoscopic sympathectomy (TS) at different denervation levels for palmar hyperhidrosis. We searched PubMed, Ovid MEDLINE, EMBASE, Web of Science, ScienceDirect, the Cochrane Library, Scopus and Google Scholar for relevant studies published during 1990-2016. Symptom resolution, patient satisfaction, compensatory sweating (CS), recurrence, dry hands and gustatory sweating were assessed. Read More

    Comparison between high and low levels thoracic sympathectomy for the treatment of palmar and axillary primary hyperhidrosis: systematic review and meta-analysis.
    Rev Col Bras Cir 2016 Dec;43(6):486-492
    Medical School, University of Marília, Marília, São Paulo, Brazil.
    Primary hyperhidrosis (PH) is a condition that has a great impact on affected individuals' quality of life, regardless of its location. Its surgical treatment is done through thoracic sympathectomy performed by videothoracoscopy. Standardization of the technique includes section of the sympathetic trunk at different levels, according to the site of symptoms. Read More

    Methadone-Induced Hyperhidrosis Treated With Oxybutynin.
    J Addict Med 2017 Feb 27. Epub 2017 Feb 27.
    Department of Psychiatry, Metropolitan Hospital Center, New York Medical College, New York, NY.
    Objectives: This case report aims to help healthcare providers and methadone clinic patients to recognize one of the less recognized adverse effects of methadone, hyperhidrosis, and to suggest oxybutynin as a possible solution.

    Methods: A 35-year-old man on methadone maintenance therapy presented with excessive sweating, which began promptly after methadone was introduced. Urine toxicology was conducted every 2 weeks to rule out other illicit substances that may have contributed to the sweating. Read More

    Osteopathic Manipulative Treatment in the Management of Isaacs Syndrome.
    J Am Osteopath Assoc 2017 Mar;117(3):194-198
    Isaacs syndrome is a rare neuromuscular disorder characterized by chronic muscle stiffness, cramping, fasciculations, myokymia, and hyperhidrosis. Pathogenesis includes autoimmunity, paraneoplastic disorders, genetic predisposition, or toxin exposure. There is no known cure for Isaacs syndrome. Read More

    Botulinum toxin in the management of head and neck disorders.
    Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Apr 7;123(4):419-428. Epub 2016 Dec 7.
    Department of Oral Medicine and Radiology, New Horizon Dental College and Research Institute, Sakri, Bilaspur, India.
    Botulinum toxin is a polypeptide protoxin synthesized by Clostridium botulinum that results in localized reduction of muscle activity by inhibiting acetylcholine release at the neuromuscular junction. In 2004, the US Food and Drug Administration approved its application in the treatment of various medical conditions, such as facial wrinkles, strabismus, cervical dystonia, blepharospasm, and hyperhidrosis. Later, its application extended to improving dental esthetics and gummy smile. Read More

    Drug safety and adverse drug reaction reporting behavior related to outpatient opioid replacement therapy: Results from a survey among physicians.
    J Subst Abuse Treat 2017 Mar 14;74:7-15. Epub 2016 Dec 14.
    University of Ulm, Department of Psychiatry and Psychotherapy III, Leimgrubenweg 12-14, 89075 Ulm, Germany.
    To study drug safety and the reporting behavior of adverse drug reactions (ADR) related to agents used for opioid replacement therapy (ORT) we conducted a cross-sectional questionnaire-based telephone survey among physicians who provide outpatient ORT in Germany (n=176; response rate=55.7%). Most respondents (n=97/55. Read More

    Initial study of transdermal oxybutynin for treating hyperhidrosis.
    J Dermatol 2017 Jan 20. Epub 2017 Jan 20.
    Dermatology Department, Hospital Costa del Sol, Marbella, Málaga, Spain.
    Oral oxybutynin for treating hyperhidrosis is effective and safe. Its side-effects are mild but frequent so we consider whether transdermal oxybutynin (considered to have a better side-effect profile) could be an alternative for treating hyperhidrosis. During 2015, a prospective study was conducted. Read More

    [Fabry disease].
    Ann Dermatol Venereol 2017 Feb 16;144(2):137-146. Epub 2017 Jan 16.
    Département de dermatologie, Hôpital Hôtel-Dieu de France, Faculté de médecine, Université Saint-Joseph, Beyrouth, Liban.
    Fabry disease, also known as Anderson-Fabry disease or angiokeratoma corporis diffusum universale, is an X-linked recessive form of sphingolipidosis caused by total or partial deficiency of the lysosomal hydrolase, alpha-galactosidase A. From the youngest age, it results in a gradual ubiquitous build-up of glycosphingolipids that are not degraded by the missing enzyme. Cutaneous, neurological, nephrologic, cardiac, gastrointestinal, ophthalmological, respiratory, cochleovestibular and haematological involvement are responsible for increased mortality and significant impairment of quality of life in subjects affected by the disease. Read More

    Palmar hyperhidrosis: clinical, pathophysiological, diagnostic and therapeutic aspects.
    An Bras Dermatol 2016 Nov-Dec;91(6):716-725
    Universidade Estadual Paulista "Júlio de Mesquita Filho" (Unesp) - Botucatu (SP), Brazil.
    Palmar hyperhidrosis affects up to 3% of the population and inflict significant impact on quality of life. It is characterized by chronic excessive sweating, not related to the necessity of heat loss. It evolves from a localized hyperactivity of the sympathetic autonomic system and can be triggered by stressful events. Read More

    Clonidine is effective for the treatment of primary idiopathic hyperhidrosis and hot flushes: a case report.
    J Med Case Rep 2017 Jan 17;11(1):16. Epub 2017 Jan 17.
    Internal Medicine Department, College of Medicine, Prince Sattam bin Abdulaziz University, P.O. Box 173, Al-Kharj, 11942, Saudi Arabia.
    Background: While primary hyperhidrosis can be seen in men, accompanying hot flushes is rarely seen in men. Primary hyperhidrosis is thought to be related to overactivity of the sympathetic nervous system while hot flushes are believed to be related to altered peripheral vascular reactivity and a narrowed thermoregulatory zone.

    Case Presentation: I report the case of a 29-year-old man of Arab origin who presented to a dermatology clinic with a complaint of generalized sweating, with heavier involvement of his inguinal region, axilla, and lower back. Read More

    The impact of skin diseases on quality of life: A multicenter study.
    Actas Dermosifiliogr 2017 Apr 4;108(3):244-252. Epub 2017 Jan 4.
    Grupo de Investigación Dermatológica (GRID), Universidad de Antioquia, Medellín, Colombia.
    Introduction: To date, no formal study has been published regarding how Colombian patients with skin disorders could be affected according to their perception of disease.

    Objective: To determine the impact in quality of life of skin diseases in a Colombian population.

    Methods: This multicenter study included patients with skin disease from almost the whole country. Read More

    Spinal fusion and antibiotic treatment illustrating lumbar osteomyelitis and spinal instability as a previously unrecognized and surgically treatable cause of autonomic dysreflexia.
    Spinal Cord Ser Cases 2016 21;2:16013. Epub 2016 Jul 21.
    Department of Neurosurgery, Penn State Hershey Medical Center , Hershey, PA, USA.
    Autonomic dysreflexia (AD) following spinal cord injury can lead to a physiologic state where there is unopposed sympathetic tone and subsequent hypertension, bradycardia, hyperhidrosis and anxiety. It is known to be triggered by nociceptive stimuli below the level of injury-most commonly constipation and bladder retention. We present a case of a C6-7 tetraplegic who developed AD 20 years after his injury with the unusual trigger of positional spinal instability due to osteomyelitis and discitis. Read More

    BoNT/AB hybrid maintains similar duration of paresis as BoNT/A wild-type in murine running wheel assay.
    Neurotoxicology 2017 Mar 30;59:1-8. Epub 2016 Dec 30.
    Institut für Toxikologie, Medizinische Hochschule Hannover, Hannover, Germany. Electronic address:
    The highly potent Botulinum neurotoxins (BoNT) are successful drugs to treat neuromuscular disorders. Efforts are being made to further reduce the injected BoNT dose and to lengthen the interval between treatments. Detailed knowledge of the BoNT structure-activity relationship (SAR) allows combining the best features of the different BoNT serotypes. Read More

    A case of anti aquapolin-4 antibody positive myelitis with hyperhidrosis, following herpes zoster.
    Rinsho Shinkeigaku 2017 Jan 23;57(1):26-28. Epub 2016 Dec 23.
    Department of Neurology, Toranomon Hospital.
    We report an acute myelitis in a 53-year-old woman that occurred in 7 days after the diagnosis of Th5-6 herpes zoster. Clinical examination revealed hyperhidrosis of left side of her face, neck, arm and upper chest. She also had muscle weakness of her left leg and sensory impairment for light touch and temperature in her chest and legs. Read More

    Translation and validation of Hyperhidrosis Disease Severity Scale.
    Rev Assoc Med Bras (1992) 2016 Dec;62(9):843-847
    Vascular Surgery Department, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
    Introduction: The evaluation of patients with hyperhidrosis (HH) can be accomplished, among other ways, through questionnaires and scales. The Hyperhidrosis Disease Severity Scale (HDSS) has been used as a simple and quick tool to perform this evaluation. Although HDSS has been well established in several languages, it has not been translated into Portuguese, restricting its specific use for Brazilian patients. Read More

    [Anesthetic effect and safety of ultrasound-guided thoracic paravertebral blockade in sympathectomy for palmar hyperhidrosis: a randomized controlled trial].
    Nan Fang Yi Ke Da Xue Xue Bao 2016 Dec;36(12):1655-1659
    Department of Anesthesiology, Guangdong General Hospital and Guangdong Academy of Medical Science, Guangzhou 510080, China. E-mail:
    Objective: To explore the anesthetic effect and safety of ultrasound-guided thoracic paravertebral blockade in video-assisted thoracoscopic sympathectomy for treatment of palmar hyperhidrosis.

    Methods: A total of 120 patients undergoing video-assisted thoracoscopic sympathectomy for moderate or severe hyperhidrosis were randomized to receive ultrasound-guided thoracic paravertebral blockade (group A, n=60) or general anesthesia with tracheal intubation (group B, n=60). In both groups routine monitoring and radial artery catheterization were used. Read More

    Great saphenous vein dilatation with reflux at the saphenofemoral junction: A rare underlying association of eccrine angiomatous hamartoma.
    Indian Dermatol Online J 2016 Nov-Dec;7(6):533-535
    Department of Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College (DMIMSU-DU), Sawangi, Wardha, Maharashtra, India.
    Eccrine angiomatous hamartoma (EAH) is an exceedingly rare benign tumor-like lesion prevalent in childhood, which can produce pain and marked sweating. Histological features include proliferation of eccrine sweat glands and angiomatous capillary channels. It may be rarely associated with underlying pathological conditions. Read More

    Relationship between anxiety, depression and quality of life with the intensity of reflex sweating after thoracoscopic sympathectomy for treatment of primary hyperhidrosis.
    Rev Col Bras Cir 2016 Sep-Oct;43(5):354-359
    Post-graduate Program in Surgery Sciences, Faculty of Medical Sciences, Campinas State University (Unicamp), Campinas, SP, Brazil.
    Objective:: to compare the intensity of reflex sweating with the degree of anxiety and its interference in the quality of life of patients undergoing Thoracoscopic (VATS) sympathectomy in the pre- and postoperative period.

    Methods:: we evaluated 54 patients with a mean age of 26 years (16-49 years) undergoing sympathectomy in the R3-R4 level. We applied two questionnaires at three different times: "Quality of life in patients with primary hyperhidrosis" and "Scale for anxiety and depression". Read More

    A new case series of Crisponi syndrome in a Turkish family and review of the literature.
    Clin Dysmorphol 2017 Apr;26(2):66-72
    aDepartment of Neonatology, Bezmialem Vakif University bHaseki Teaching and Research Hospital, Pediatric Intensive Care Unit, Istanbul, Turkey cInstitute of Biomedical and Genetics Research, National Research Council, Monserrato, Italy.
    Crisponi syndrome/cold-induced sweating syndrome (CS/CISS) is a rare autosomal recessive disorder with a complex phenotype, reported in the neonatal period for CS and in the evolutive one for CISS. The syndrome usually manifests at birth. The aim of this study was to report on three new patients with CS and review the Turkish patients. Read More

    Treatment of primary hyperhidrosis with oral anticholinergic medications: a systematic review.
    J Eur Acad Dermatol Venereol 2016 Dec 15. Epub 2016 Dec 15.
    Department of Surgery, Royal Free Hospital, London, UK.
    Primary hyperhidrosis is a condition characterized by excessive sweating. Patients are treated off-license with oral anticholinergic medications and report adverse events associated with systemic anticholinergic interactions. This review assesses clinical evidence of efficacy, impact on quality of life and adverse events associated with oral anticholinergic therapy for primary hyperhidrosis. Read More

    Parotid Branches of the Auriculotemporal Nerve: An Anatomical Study With Implications for Frey Syndrome.
    J Craniofac Surg 2017 Jan;28(1):262-264
    *Seattle Science Foundation, Seattle, WA †Department of Anatomy, Kurume University School of Medicine ‡Dental and Oral Medical Center, Kurume University School of Medicine, Kurume, Japan §Swedish Neuroscience Institute, Swedish Medical Center ||Swedish Maxillofacial Surgery, Swedish Medical Center, Seattle, WA.
    The auriculotemporal nerve is one of the many branches of the mandibular division of the trigeminal nerve. Of these, its superficial temporal branch has been most described. Although the parotid branches, secretomotor fibers to the parotid gland, are well known as the cause of Frey syndrome, there have been almost no descriptions of their anatomy. Read More

    [Use of intracutaneous or subcutaneous botulinum toxin for postherpetic neuralgia].
    Nervenarzt 2017 Apr;88(4):408-414
    Universitätsklinik für Anästhesiologie und Intensivmedizin, Klinische Abteilung für Spezielle Anästhesiologie, Schmerz- und Intensivmedizin, Medizinische Universität Graz, Auenbruggerplatz 29, 8036, Graz, Österreich.
    Background: Botulinum neurotoxin (BoNT), a toxin of the anaerobic spore-forming bacterium Clostridium botulinum is used as a drug for alleviating muscle spasticity. Other indications include the cosmetic application in facial muscles, hyperhidrosis and neurogenic bladder disorders. It has been approved since 2010 as the first prophylactic treatment for chronic migraine. Read More

    Tap water iontophoresis in the treatment of pediatric hyperhidrosis.
    J Pediatr Surg 2017 Feb 14;52(2):309-312. Epub 2016 Nov 14.
    Department of Dermatology, University Hospitals of Leicester, Leicester, UK.
    Aim Of The Study: The treatment options for localized hyperhidrosis include antiperspirants, anticholinergics, iontophoresis, botulinum toxin and surgery. Tap water iontophoresis (TWI) involves immersing the affected area in tap water and passing a small electrical current through the area. Our aim was to assess the success of this therapy in a pediatric cohort. Read More

    Thoracoscopic bilateral T3 sympathectomy for primary focal hyperhidrosis in children.
    J Pediatr Surg 2017 Feb 14;52(2):313-316. Epub 2016 Nov 14.
    Division of General, Thoracic and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
    Aim Of The Study: Present our experience in the surgical treatment of primary focal hyperhidrosis of the hands by thoracoscopic bilateral T3 sympathectomy in pediatric patients.

    Methods: Retrospective chart review of all patients operated between 2013 and 2015.

    Results: We operated and included in the study 28 patients, 22 females and 6 males. Read More

    Treatment of Palmar Hyperhidrosis With Needle Injection Versus Low-Pressure Needle-Free Jet Injection of OnabotulinumtoxinA: An Open-Label Prospective Study.
    Dermatol Surg 2017 Feb;43(2):264-269
    *All authors are affiliated with the Department of Medicine, Dermatology Division, Hôpital Saint-Luc du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec.
    Background: OnabotulinumtoxinA (OnabotA) injections are effective to treat palmar hyperhidrosis (HH) but are quite painful.

    Objective: To evaluate efficacy and pain of OnabotA injection using a needle-free jet apparatus compared with the traditional needle injection to treat palmar HH.

    Methods: Twenty patients were recruited for a prospective open-label study. Read More

    Cardiac Autonomic Changes After Thoracic Sympathectomy: A Prospective, Randomized Study.
    Ann Thorac Surg 2017 Jan 23;103(1):216-224. Epub 2016 Nov 23.
    Department of Cardio-Thoracic Science, Thoracic Surgery Unit, Second University of Naples, Naples, Italy.
    Background: We evaluated whether cardiac autonomic changes could be associated with different extent of sympathetic nerve resection in the management of essential palmar hyperhidrosis.

    Methods: Sixty patients with essential palmar hyperhidrosis were randomly allocated to undergo excision of T3 ganglia (sympathicectomy group; n = 30) or to interruption of sympathetic chain at the T2 to T3 level with ganglion sparing (sympathicotomy group; n = 30). Time and frequency domains were measured with a 24-Holter monitor during daytime, nighttime, and 24-hour periods at different interval points (7 days before operation; 24 hours; and 1, 3, and 6 months later), and the differences were statistically compared. Read More

    Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency.
    BMC Med Genet 2016 Nov 24;17(1):88. Epub 2016 Nov 24.
    Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
    Background: The WNT10A protein is critical for the development of ectodermal appendages. Variants in the WNT10A gene may be associated with a spectrum of ectodermal abnormalities including extensive tooth agenesis.

    Methods: In seven patients with severe tooth agenesis we identified anomalies in primary dentition and additional ectodermal symptoms, and assessed WNT10A mutations by genetic analysis. Read More

    Prevalence of Multifocal Primary Hyperhidrosis and Symptom Severity Over Time: Results of a Targeted Survey.
    Dermatol Surg 2016 Dec;42(12):1347-1353
    *Department of Dermatology, St. Louis University School of Medicine, St. Louis, Missouri; †International Hyperhidrosis Society, Charleston, South Carolina; ‡Candesant Biomedical, Palo Alto, California; §Department of Dermatology, Eastern Virginia Medical School, Norfolk, Virginia.
    Background: There is a paucity of data on the prevalence of multifocal primary hyperhidrosis and changes in hyperhidrosis severity over time.

    Objective: The goal of this study was to better understand multifocal primary hyperhidrosis, prevalence and distribution of hyperhidrosis by focal site, age of onset of symptoms by focal area, and change in hyperhidrosis severity over time and with seasons.

    Materials And Methods: The International Hyperhidrosis Society, through an unrestricted research grant from Revance Therapeutics, conducted an online survey of registered visitors to its Web site. Read More

    1 OF 86