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    1 OF 87

    Iodine-Starch test for assessment of hyperhidrosis in amputees, evaluation of different methods of application.
    Disabil Rehabil 2017 Aug 21:1-5. Epub 2017 Aug 21.
    a Division of Physical Medicine and Rehabilitation , University of Utah School of Medicine , Salt Lake City , UT , USA.
    Purpose: Hyperhidrosis is a common problem for amputees. The iodine-starch test is frequently used to assess hyperhidrosis, but a method for its application has not been described for amputees.

    Methods: We performed an unblinded comparison of the iodine-starch test using various methods to protect the prosthesis in 10 prosthetic limb users with hyperhidrosis. Read More

    The Etiology of Primary Hyperhidrosis: A Systematic Review.
    Clin Auton Res 2017 Aug 19. Epub 2017 Aug 19.
    Department of Cardiothoracic Surgery, Odense University Hospital, Odense, 5000, Denmark.
    Purpose: Primary hyperhidrosis is a pathological disorder of unknown etiology, affecting 0.6-5% of the population, and causing severe functional and social handicaps. As the etiology is unknown, it is not possible to treat the root cause. Read More

    A novel organotypic 3D sweat gland model with physiological functionality.
    PLoS One 2017 10;12(8):e0182752. Epub 2017 Aug 10.
    Henkel AG & Co. KGaA, Düsseldorf, Germany.
    Dysregulated human eccrine sweat glands can negatively impact the quality-of-life of people suffering from disorders like hyperhidrosis. Inability of sweating can even result in serious health effects in humans affected by anhidrosis. The underlying mechanisms must be elucidated and a reliable in vitro test system for drug screening must be developed. Read More

    Keratin 17 Mutations in Four Families from India with Pachyonychia Congenita.
    Indian J Dermatol 2017 Jul-Aug;62(4):422-426
    School of Life Sciences, Division of Biological Chemistry and Drug Discovery, Dermatology and Genetic Medicine, University of Dundee, Dundee, UK.
    Pachyonychia congenita (PC) is a rare autosomal dominant genetic skin disorder due to a mutation in any one of the five keratin genes, KRT6A, KRT6B, KRT6C, KRT16, or KRT17. The main features are palmoplantar keratoderma, plantar pain, and nail dystrophy. Cysts of various types, follicular hyperkeratosis, oral leukokeratosis, hyperhidrosis, and natal teeth may also be present. Read More

    Acquired Ulcero-Mutilating Bilateral Acro-Osteopathy (Bureau-Barrière Syndrome).
    Open Access Maced J Med Sci 2017 Jul 24;5(4):558-560. Epub 2017 Jul 24.
    Abdominal and Thoracic Surgery, Department of Special Surgery, Medical University of Plovdiv, bul. "Peshtersko shose" Nr 66, 4000 Plovdiv, Bulgaria.
    We present a 35-year-old male patient with Bureau-Barrière syndrome. Bureau-Barrière syndrome is an ulcero-mutilating acropathy almost invariably associated with excessive alcohol intake. It presents with a triad of trophic skin changes with recurrent ulcerations, bone lesions and nerve damage. Read More

    Hyperhidrosis Substantially Reduces Quality of Life in Children: A Retrospective Study Describing Symptoms, Consequences and Treatment with Botulinum Toxin.
    Acta Derm Venereol 2017 Aug 1. Epub 2017 Aug 1.
    Hidrosis Clinic, Warfvinges väg 35, SE-112 51 Stockholm, Sweden.
    Studies on children with hyperhidrosis are sparse. This retrospective study presents clinical data and quality of life, along with treatment effect and safety of botulinum toxin (BTX). Case reports from 366 children were included to capture the medical history of hyperhidrosis. Read More

    Strategies to decrease injection site pain in botulinum toxin therapy.
    J Neural Transm (Vienna) 2017 Jul 24. Epub 2017 Jul 24.
    Movement Disorders Section, Department of Neurology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
    Botulinum toxin is now used for numerous indications including dystonias, spasticity, cerebral palsy, hyperhidrosis, cosmetics and chronic migraine. It has to be injected into its target tissues thus causing injection site pain. We wanted to compare the efficacy of various analgesic interventions suggested for reduction of injection site pain. Read More

    Sequential Extended Thoracoscopic Sympathicotomy for Palmo-Axillo-Plantar Hyperhidrosis.
    Ann Thorac Surg 2017 Jul 17. Epub 2017 Jul 17.
    General Surgery Department, Mansoura University, Egypt.
    Background: Palmo-axillo-plantar hyperhidrosis (HH) exists in approximately 70% to 100% of patients complaining of HH. Many studies have documented variable effects of thoracoscopic sympathicotomy (TS) on plantar sweating. The present trial evaluated sequential extended thoracoscopic sympathicotomy for the treatment of palmo-axillo-plantar HH regarding its feasibility and outcome on each domain of HH, particularly the plantar domain METHODS: Forty-two patients with severe palmo-axillo-plantar HH underwent sequential extended (T3 to T12) thoracoscopic sympathicotomy. Read More

    [Evaluation and management of hyperhidrosis].
    Rev Med Suisse 2017 Mar;13(556):710-714
    Service de dermatologie et vénéréologie, HUG, 1211 Genève 14.
    Hyperhidrosis is excessive sweating beyond what is expected for thermoregulatory needs. Nearly 3 % of the population has hyperhidrosis. It may be primary or secondary to medications or general medical conditions, including diabetes mellitus, hyperthyroidism, Parkinson disease, etc. Read More

    Interventions for treating lymphocytic colitis.
    Cochrane Database Syst Rev 2017 Jul 13;7:CD006096. Epub 2017 Jul 13.
    London Health Sciences Centre - Victoria Hospital, Room E6-321A, 800 Commissioners Road East, London, ON, Canada, N6A 5W9.
    Background: Lymphocytic colitis is a cause of chronic diarrhea. It is a subtype of microscopic colitis characterized by chronic, watery, non-bloody diarrhea and normal endoscopic and radiologic findings. The etiology of this disorder is unknown. Read More

    Video-Assisted Thoracoscopic Sympathectomy for Facial Hyperhidrosis: The Influence of the Main Site of Complaint.
    Ann Vasc Surg 2017 Jul 6. Epub 2017 Jul 6.
    Division of Vascular and Endovascular Surgery, Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil; Division of Vascular and Endovascular Surgery, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
    Introduction: Facial hyperhidrosis (FH) may lead patients to a significantly impaired quality of life (QOL). Video-assisted thoracoscopic sympathectomy (VATS) is reserved for more severe cases refractory to common first-line agents. The aim of this study was to evaluate the efficacy of VATS for FH and to compare the results between patients with facial hyperhidrosis as main complaint (FHMC) and patients with facial hyperhidrosis as nonmain complaint (FHNMC). Read More

    Brachial plexus injury after microwave-based treatment for axillary hyperhidrosis and osmidrosis.
    J Cosmet Laser Ther 2017 Jun 28:1-3. Epub 2017 Jun 28.
    a Department of Plastic Surgery , Tri-Service General Hospital , Taipei , Taiwan.
    Axillary hyperhidrosis combined with osmidrosis is a common problem, especially in Asian communities, that patients find annoying. Even though several surgical techniques have been reported to treat hyperhidrosis/osmidrosis permanently, patients would prefer a non-surgical approach. A microwave-based device was invented during this decade, and it has proven to be a safe and efficient way to treat axillary hyperhidrosis/osmidrosis without major complications. Read More

    Topical Oxybutynin 10% Gel for the Treatment of Primary Focal Hyperhidrosis: A Randomized Double-blind Placebo-controlled Split Area Study.
    Acta Derm Venereol 2017 Jun 27. Epub 2017 Jun 27.
    Department of Dermatology, Tel Aviv Medical Center, 6 Weizman Street, Tel Aviv, 6423906, Israel.
    Limited efficacy, costs, side-effects and complications are issues of concern for most current therapeutic modalities for focal hyperhidrosis. This study evaluated the efficacy of topical oxybutynin 10% gel in treating 61 patients with primary focal hyperhidrosis. The gel was applied to the right or left axilla, palms or soles vs. Read More

    Klippel-Trenauney syndrome with axillary hyperhidrosis.
    Dermatol Online J 2017 Jun 15;23(6). Epub 2017 Jun 15.
    MD Program, Tufts University School of Medicine, Boston, Massachusetts,.
    Klippel-Trenaunay syndrome (KTS) is a rare, clinically variable congenital disorder involving capillary malformations, soft tissue or bone hypertrophy, and venous malformations or varicose veins. We report a 28-year-old man who presented with a hypertrophic right arm as well as markedly increased ipsilateral axillary hyperhidrosis and erythematous patches on the back, chest, and arm. This case of KTS is unusual because our patient presented with a markedly increased unilateral axillary hyperhidrosis ipsilateral to the hypertrophic limb. Read More

    Early-Onset Shapiro Syndrome Variant Treated with Pizotifen: A Case Report.
    Neurodiagn J 2017 ;57(2):139-146
    a Child Neuropsychiatry Unit , Giannina Gaslini Pediatric Institute , Genoa , Italy.
    Shapiro Syndrome is a rare entity defined by the triad of recurrent spontaneous hypothermia, hyperhidrosis, and agenesis of the corpus callosum. Fewer than 100 cases have been reported so far and there are only few cases without a complete agenesis of corpus callosum ("Shapiro Syndrome Variant"). In this article, we report the clinical, electroencephalographic, and neuroimaging data of a patient with early-onset Shapiro Syndrome Variant. Read More

    Skin findings in autoimmune and nonautoimmune thyroid disease with respect to thyroid functional status and healthy controls.
    Turk J Med Sci 2017 Jun 12;47(3):764-770. Epub 2017 Jun 12.
    Department of Dermatology, İstanbul Medeniyet University, Göztepe Research and Training Hospital, İstanbul, Turkey.
    Background/aim: Thyroid disorders are associated with a wide variety of skin disorders that respond to treatment of hormone imbalance in most cases and thus are of vital importance to dermatologists. This study aimed to evaluate skin findings associated with autoimmune and nonautoimmune thyroid disease with respect to thyroid functional status and healthy controls.

    Materials And Methods: A total of 300 consecutive patients with either autoimmune (n = 173) or nonautoimmune (n = 127) thyroid disease and 100 healthy control subjects were included in this cross-sectional study. Read More

    Botulinum Toxin Off-Label Use in Dermatology: A Review.
    Skin Appendage Disord 2017 Mar 1;3(1):39-56. Epub 2017 Feb 1.
    Dermatology Unit, Department of Clinical and Molecular Sciences, United Hospital of Ancona, Polytechnic Marche University, Ancona, Italy.
    Background: Botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It is currently used for aesthetic treatments and in the focal hyperhidrosis. Recently, botulinum toxin has also been used experimentally in many other dermatological conditions with good results. Read More

    [Assessment of the radial and ulnar arteries hemodynamic changes by ultrasound in patients with primary palmar hyperhidrosis after thoracic sympathetic block].
    Zhonghua Yi Xue Za Zhi 2017 Jun;97(22):1729-1733
    Department of Anesthesiology and Pain Medicine, the First Hospital of Jiaxing City, Zhejiang Province, Jiaxing 314001, China.
    Objective: To evaluate the value of radial and ulnar arteries hemodynamic changes by ultrasound in patients with primary palmar hyperhidrosis after thoracic sympathetic block. Methods: This was a prospective study, from January 2016 to September 2016, 23 patients with primary palmar hyperhidrosis were admitted to the First Hospital of Jiaxing City, Zhejiang Province, 92 arteries of these patients who underwent thoracic sympathetic block were enrolled into this study. Diameters, peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive index (RI) of the radial and ulnar arteries were examined one day before and after the operation by color Doppler ultrasound. Read More

    The impact of hyperhidrosis on patients' daily life and quality of life: a qualitative investigation.
    Health Qual Life Outcomes 2017 Jun 8;15(1):121. Epub 2017 Jun 8.
    Institute of Medicines Development, Duffryn House, Cardiff, CF, 23 6NP, UK.
    Background: An understanding of the daily life impacts of hyperhidrosis and how patients deal with them, based on qualitative research, is lacking. This study investigated the impact of hyperhidrosis on the daily life of patients using a mix of qualitative research methods.

    Methods: Participants were recruited through hyperhidrosis patient support groups such as the Hyperhidrosis Support Group UK. Read More

    Dependent Erythema of the Legs Associated With Mild Autonomic Nervous System Dysfunction.
    J Cutan Med Surg 2017 Jun 1:1203475417714801. Epub 2017 Jun 1.
    2 Department of Medicine, Memorial University, St John's, NL, Canada.
    Introduction: Dependent erythema or rubor is an erythematous discoloration of the limbs, most commonly associated with peripheral artery disease. We present a case of florid dependent erythema, associated with additional autonomic symptoms.

    Methods: Examination and full workup of a 16-year-old healthy girl with an 8-year history of dependent erythema, chronic diarrhea, and mild hyperhidrosis. Read More

    Comparison of the Long-Term Results of R3 and R4 Sympathicotomy for Palmar Hyperhidrosis.
    Korean J Thorac Cardiovasc Surg 2017 Jun 5;50(3):197-201. Epub 2017 Jun 5.
    Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine.
    Background: Video-assisted thoracoscopic sympathicotomy has been determined to be the best way to treat palmar hyperhidrosis. However, satisfaction with the surgical outcomes decreases with the onset of compensatory hyperhidrosis (CH) over time. The ideal level of sympathicotomy is controversial. Read More

    Mahuannin B an adenylate cyclase inhibitor attenuates hyperhidrosis via suppressing β2-adrenoceptor/cAMP signaling pathway.
    Phytomedicine 2017 Jul 10;30:18-27. Epub 2017 Mar 10.
    State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China. Electronic address:
    Background: Based on the traditional application of traditional Chinese Medicines (TCMs), Ephedra Herba (EH) is used to cure cold fever by inducing sweating, whereas Ephedra Radix (ER) is used to treat hyperhidrosis. Although they come from the same plant, Ephedra sinica Stapf, but have play opposing roles in clinical applications. EH is known to contain ephedrine alkaloids, which is the driver of the physiological changes in sweating, heart rate and blood pressure. Read More

    Oxybutynin as an alternative treatment for hyperhidrosis.
    An Bras Dermatol 2017 Mar-Apr;92(2):217-220
    Departament of Drugs and Medicines of the Universidade Estadual Paulista "Júlio de Mesquita Filho" (Unesp) - Botucatu (SP), Brazil.
    Hyperhidrosis is the excessive production of sweating, which can be primary and focal or secondary to various pathologies. The exact cause of primary focal hyperhidrosis is still unknown, although a genetic basis is recognized, and its prevalence varies from 1% to 2.8%. Read More

    Comparative Study of Efficacy and Safety of Botulinum Toxin a Injections and Subcutaneous Curettage in the Treatment of Axillary Hyperhidrosis.
    J Cutan Aesthet Surg 2017 Jan-Mar;10(1):33-39
    Department of Dermatology, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
    Background: Primary focal axillary hyperhidrosis is a chronic distressing disorder affecting both the sexes. When the condition is refractory to conservative management, we should go for more promising therapies like intradermal botulinum toxin A (BtxA) injections in the axilla, and surgical therapies like subcutaneous curettage of sweat glands.

    Aims And Objectives: The aim of this study is to compare the efficacy, safety and duration of action of intradermal BtxA injections in one axilla and subcutaneous curettage of sweat glands in the other axilla of the same patient with axillary hyperhidrosis. Read More

    Perfusion Index: An Indicator of Success During Endoscopic Thoracic Sympathectomy for Hyperhidrosis.
    Ann Thorac Surg 2017 Aug 17;104(2):426-430. Epub 2017 May 17.
    Division of Thoracic and Cardiovascular Surgery, University of Florida, Gainesville, Florida; Department of Anesthesiology, University of Florida, Gainesville, Florida.
    Background: Endoscopic thoracic sympathectomy (ETS) is indicated for refractory hyperhidrosis. The pulse oximetry-derived perfusion index (PI) quantifies pulsatile blood flow at the oximeter. Thoracic sympathectomy increases blood flow; thus we postulate it will reliably increase PI. Read More

    Electro-Acupuncture at Zusanli Acupoint (ST36) Suppresses Inflammation in Allergic Contact Dermatitis Via Triggering Local IL-10 Production and Inhibiting p38 MAPK Activation.
    Inflammation 2017 Aug;40(4):1351-1364
    Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Hubei University of Chinese Medicine, 1 Huangjiahu West Road, Hongshan District, Wuhan, Hubei, 430065, China.
    Acupuncture has shown beneficial effect in the treatment of multiple dermatologic conditions including dermatitis, pruritus, urticaria, and hyperhidrosis; however, the detailed mechanisms are still kept unclear. This study aimed to investigate if electro-acupuncture (EA) treatment prevents 2,4-dinitrofluorobenzene (DNFB)-induced allergic contact dermatitis (ACD) in rats and explore its underlying mechanisms. ACD was induced by sensitizing and challenging with DNFB topically. Read More

    Clinical effect of montelukast sodium combined with inhaled corticosteroids in the treatment of OSAS children.
    Medicine (Baltimore) 2017 May;96(19):e6628
    Department of Otolaryngology, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China.
    This study was designed to investigate the clinical effect of montelukast sodium combined with inhaled corticosteroids in the treatment of children with obstructive sleep apnea syndrome (OSAS).One hundred ninety-five children were enrolled and divided into 3 groups: groups A, B, and C; the group A (oral use of montelukast sodium), group B (nasal spray of mometasone furoate), and group C (oral use of montelukast sodium + nasal spray of mometasone furoate). Telephone questionnaire surveys were carried out. Read More

    Videothoracoscopic Sympathectomy Results after Oxybutynin Chloride Treatment Failure.
    Ann Vasc Surg 2017 Aug 3;43:283-287. Epub 2017 May 3.
    Department of Vascular Surgery, University of São Paulo, São Paulo, Brazil.
    Background: Videothoracoscopy sympathectomy (VATS) is the only definitive treatment for primary hyperhidrosis (HH). Since 2007, in our institution, patients with HH were initially treated with oxybutynin chloride to avoid VATS and reduce compensatory hyperhidrosis incidence with good results. The aim of this study was to analyze the surgical response of patients suffering from essential hyperhidrosis after failure of oxybutynin chloride treatment. Read More

    Botulinum toxin-induced acute anterior uveitis in a patient with Behçet's disease under infliximab treatment: a case report.
    J Med Case Rep 2017 May 4;11(1):124. Epub 2017 May 4.
    Department of Ophthalmology, Asai Hospital, 178-1 Yakata-cho, Seto, Aichi, 489-0866, Japan.
    Background: Injections of lipopolysaccharide in animal models generate acute anterior uveitis (also known as endotoxin-induced uveitis), but the effects of lipopolysaccharide injection are unknown in humans. We describe an unusual case in which acute anterior uveitis was dramatically activated subsequent to botulinum toxin injection in a patient with Behçet's disease but the acute anterior uveitis was satisfactorily attenuated by infliximab.

    Case Presentation: A 53-year-old Japanese man had normal ocular findings at his regularly scheduled appointment. Read More

    The clinical features of 590 patients with brucellosis in Xinjiang, China with the emphasis on the treatment of complications.
    PLoS Negl Trop Dis 2017 May 1;11(5):e0005577. Epub 2017 May 1.
    Department of Infection Disease Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
    Background: This study aims to analyze the clinical characteristics and treatment outcomes of 590 patients with brucellosis in Xinjiang, China.

    Methodology And Principal Findings: The clinical characteristics, laboratory findings, complications and prognosis of 590 patients infected with brucellosis were retrospectively analyzed. These patients had a mean age of 44. Read More

    Thoracic sympathectomy for hyperhidrosis: from surgical indications to clinical results.
    J Thorac Dis 2017 Apr;9(Suppl 3):S178-S192
    Thoracic Surgery Department, Hospital Federal do Andaraí, Rio de Janeiro, Brazil.
    Sympathectomy and its variations have been performed in thoracic surgery for more than 100 years. However, its indications have undergone profound modifications in this period. Likewise, since then the surgical technique has also evolved dramatically up to the minimally invasive techniques worldwide accessible in present days. Read More

    A New Device of Needlescopic Thoracic Sympathectomy Through a Skin Incision.
    Ann Thorac Surg 2017 May;103(5):e465-e467
    Department of Surgery, Kobe Health University, Kobe, Japan.
    We describe a new technique of performing sympathectomy with a new device. A single skin incision 3 mm long was made in the armpit. The device enables complete resection of the sympathetic segment through a single skin incision, whereas sympathectomy is limited by the use of the conventional needle technique. Read More

    Comparison of T2 and T3 sympathectomy for compensatory sweating on palmar hyperhidrosis.
    Medicine (Baltimore) 2017 Apr;96(16):e6697
    Department of Thoracic Surgery, Karadeniz Technical University Medical School, Trabzon, Turkey.
    Background: An otherwise successfully performed endoscopic thoracic sympathectomy (ETS) to treat palmar hyperhidrosis (PH) often has a serious side effect: compensatory sweating (CS). This side effect occurs in other parts of the body to a disturbing extent. The objective of this study is to determine whether there is a relationship between the level of ETS performed on patients with PH, and the occurrence and severity of postoperational CS. Read More

    Eccrine Nevus Presenting with Umbilical Discharge: A Case Report and Review of the Literature.
    Case Rep Dermatol Med 2017 21;2017:9761843. Epub 2017 Mar 21.
    Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Eccrine nevus is a rare skin lesion with protean manifestations like hyperhidrosis, discolored nodules, papules, and so forth, which has been reported in various anatomic parts of the body including the forearm, leg, thigh, back, and coccyx. Our patient was a 26-year-old male, who presented with increasing colorless and odorless episodic umbilical discharge. First impression for the patient was an umbilical sinus and the patient underwent surgery. Read More

    Confirmatory factor analysis of the Sleep Disturbance Scale for Children (SDSC) in a clinical sample of children and adolescents.
    J Sleep Res 2017 Apr 12. Epub 2017 Apr 12.
    School of Psychological Science, University of Western Australia, Crawley, WA, Australia.
    The Sleep Disturbance Scale for Children was developed as a parent-report measure to screen for sleep disturbances within the preceding 6 months. Notably, the scale was developed using a sample of typically developing children and children with sleep disorders. The aim of this study was to factor analyse the Sleep Disturbance Scale for Children using a clinical sample of children with a range of neuropsychological conditions and co-morbidities, and determine whether the original six-factor structure was retained. Read More

    Optimal targeting of sympathetic chain levels for treatment of palmar hyperhidrosis: an updated systematic review.
    Surg Endosc 2017 Apr 7. Epub 2017 Apr 7.
    Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jie Fang Avenue, Wuhan, 430030, Hubei, China.
    Background: Palmar hyperhidrosis involves excessive sweating of the palms, with no known etiology. Endoscopic thoracic sympathectomy (ETS) is a safe and effective treatment for palmar hyperhidrosis, but compensatory hyperhidrosis is a common complication after ETS, leading to reduced patient satisfaction and postoperative quality of life. However, the appropriate level of the sympathetic chain to target with ETS to achieve maximum efficacy and reduce the risk of compensatory hyperhidrosis (CH) is controversial. Read More

    New Uses of AbobotulinumtoxinA in Aesthetics.
    Aesthet Surg J 2017 05;37(suppl_1):S45-S58
    Dermatologist in private practice in Miami, FL, USA.
    BotulinumtoxinA (BoNT-A) is now widely established for the main approved indication of reducing glabellar lines, and is also widely used off-label to improve the appearance of wrinkles and lines in other parts of the face. The number of aesthetic procedures continues to increase as the patient population becomes more diverse, in particular with increasing numbers of people of color and men. Further developments in treatment may continue to expand the audience for BoNT-A by making procedures more comfortable and by delivering a more natural, less static appearance. Read More

    AbobotulinumtoxinA: A 25-Year History.
    Aesthet Surg J 2017 05;37(suppl_1):S4-S11
    Director and Founder of Toxin Science Limited, Wrexham, UK.
    During the late 1960s and early 1970s, Alan Scott showed that intramuscular injections of botulinum toxin (BoNT) corrected nonaccommodative strabismus without resorting to surgery. The UK doctors who trained with Scott soon realized the significant potential offered by BoNT type A as a therapeutic option for several difficult-to-treat diseases. This led to a collaboration between these pioneering clinicians and the Centre for Applied Microbiology and Research at Porton Down, United Kingdom, and, in turn, to the development and commercialization of abobotulinumtoxinA as Dysport (Dystonia/Porton Down; Ipsen Biopharm Ltd. Read More

    Percutaneous CT-Guided Sympathicolysis with Radiofrequency for the Treatment of Palmar Hyperhidrosis.
    J Vasc Interv Radiol 2017 Jun 30;28(6):877-885. Epub 2017 Mar 30.
    Radiology Service, Clinica Universidad de Navarra, Pamplona, Spain.
    Purpose: To evaluate the benefits of computed tomography (CT)-guided percutaneous sympathicolysis with radiofrequency in patients with primary palmar hyperhidrosis (PPHH) in terms of safety, patient satisfaction, and short- and long-term efficacy.

    Materials And Methods: A total of 139 procedures in 108 patients (mean age, 29.89 y ± 10. Read More

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