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    1 OF 89

    Evaluation of Quality of Life: Functional Assessment of Chronic Illness Therapy after Thoracic Sympathectomy for Palmar Hyperhidrosis.
    Thorac Cardiovasc Surg 2018 Apr 19. Epub 2018 Apr 19.
    Department of General, Endocrine and Transplant Surgery, Gdanski Uniwersytet Medyczny, Gdansk, Poland.
    Background:  Primary hyperhidrosis is a condition that significantly decreases the quality of life (QOL). Thoracic sympathectomy is safe and efficient method of treatment in palmar hyperhidrosis.

    Objective:  The aim of the study was to evaluate the change in QOL in patients with palmar hyperhidrosis who underwent thoracic sympathectomy. Read More

    Investigation on Aetiological Factors in Patients with Hyperhidrosis.
    Cutan Ocul Toxicol 2018 Apr 18:1-17. Epub 2018 Apr 18.
    a Department of Dermatology , Ministry of Health Atatürk Training and Research Hospital , Ankara , Turkey.
    Background: Hyperhidrosis is a condition where the amount of sweat released to skin surface increases due to the over-active eccrine sweat glands. Hyperhidrosis causes considerable psychosocial distress in affected people. It affects the quality of life and leads to social anxiety disorders. Read More

    [Videothoracoscopic Sympathetic Clipping in a Patient With Azygos Lobe. Intraoperative Management to Avoid Potential Complications].
    Zentralbl Chir 2018 Apr 17. Epub 2018 Apr 17.
    Thoraxchirurgische Abteilung in der Chirurgischen Klinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland.
    Introduction: Sympathetic clipping in the presence of an azygos lobe is a rare combination. Anatomical relations between the sympathetic trunk and the mesoazygos impede surgical handling and can be associated with potential complications.

    Indication: We report the case of a 25-year old woman with grade III palmoplantar and axillary hyperhidrosis with azygos lobe incidentally found on preoperative chest X-ray. Read More

    A comparative trial of ice application versus EMLA cream in alleviation of pain during botulinum toxin injections for palmar hyperhidrosis.
    Clin Cosmet Investig Dermatol 2018 3;11:137-140. Epub 2018 Apr 3.
    Department of Dermatology, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia.
    Background: Botulinum toxin is a safe and effective therapy for palmar hyperhidrosis, but the associated pain from injections limits the usefulness of this method of treatment.

    Purpose: To evaluate the efficacy of Eutectic Mixture of Local Anesthetics (EMLA) cream versus ice application in alleviation of pain during botulinum toxin injections for palmar hyperhidrosis.

    Methods: In this prospective study, 23 patients underwent palm Botox injections to treat their excessive sweating. Read More

    Topical Botulinum Toxin Type A Liposomal Cream for Primary Axillary Hyperhidrosis: A Double-Blind, Randomized, Split-Site, Vehicle-Controlled Study.
    Dermatol Surg 2018 Apr 13. Epub 2018 Apr 13.
    Department of Pediatrics, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Pathumwan, Bangkok, Thailand.
    Background: Despite its effectiveness in treating primary axillary hyperhidrosis (PAH), topical botulinum toxin type A (BTX-A) is highly resistant to transdermal absorption. Topical BTX-A liposomal cream is recommended as a novel, noninvasive modality to enhance skin penetration.

    Objective: To evaluate the efficacy and safety of topical BTX-A liposomal cream in comparison with liposomal vehicle cream alone in the treatment of PAH. Read More

    Postoperative Harlequin Syndrome: Case Report of a Rare but Clinically Striking Condition.
    A A Pract 2018 Apr;10(8):215-217
    From the Departments of Anesthesiology, Pediatric Anesthesiology, and Pediatric General Surgery, New York Medical College at Westchester Medical Center, Valhalla, New York.
    We present a case of a 2-year-old boy who underwent thoracoscopic resection of a left paraspinal mediastinal mass and developed Harlequin syndrome postoperatively. Harlequin syndrome is a rare neurological condition characterized by unilateral hyperhidrosis and erythema of the head and neck. Our discussion highlights this condition and other differential diagnoses that may present similarly in the postoperative period. Read More

    Combination of topical agents and oxybutynin as a therapeutic modality for patients with both osmidrosis and hyperhidrosis.
    Rev Assoc Med Bras (1992) 2018 Feb;64(2):127-132
    Division of Vascular and Endovascular Surgery, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
    Introduction: The association of osmidrosis and hyperhidrosis often causes emotional and social problems that may impair the patients' quality of life. The purpose of our study was to analyze the therapeutic results of oxybutynin and topical agents in 89 patients with both osmidrosis and hyperhidrosis.

    Method: We conducted an observational study at two specialized centers of hyperhidrosis between April 2007 and August 2013. Read More

    An open prospective pilot study of a herbal combination "Relief" as a supportive dietetic measure during alcohol withdrawal.
    Neuro Endocrinol Lett 2018 Mar 1;39(1):1-8. Epub 2018 Mar 1.
    OncoTherapeutica, Inc., MA, USA.
    Objective: A herbal combination (saffron extract, passion flower herb extract, cocoa seed extract, radish extract and black cumin extract) called "Relief" was designed as a supportive therapy of alcohol withdrawal syndrome (AWS). This combination was based on the scientific evidence of each constituent effect on AWS-like symptoms. In addition, our preclinical studies have shown the effectiveness of Relief on AWS detoxification. Read More

    Understanding Patient Experience With Hyperhidrosis: A National Survey of 1,985 Patients.
    J Drugs Dermatol 2018 Apr;17(4):392-396
    Hyperhidrosis affects 4.8% of the US population, and despite the well documented negative impact of hyperhidrosis on patients' lives, data are generally lacking on the patient experience with this condition. The International Hyperhidrosis Society (IHHS) conducted a study in 2014, and initial results confirmed the multifaceted impact of hyperhidrosis on quality of life and underscored the need for disease awareness and effective management. Read More

    Interventional Management of Hyperhidrosis in Secondary Care: A Systematic Review.
    Br J Dermatol 2018 Mar 24. Epub 2018 Mar 24.
    Centre for Reviews and Dissemination, University of York.
    Background: Hyperhidrosis is uncontrollable excessive sweating, which occurs at rest, regardless of temperature. The symptoms of hyperhidrosis can significantly affect quality of life.

    Objectives: To undertake a systematic review of the clinical effectiveness and safety of treatments available in secondary care for the management of primary hyperhidrosis. Read More

    Curative effect of minimally invasive surgery on palmar and foot hyperhidrosis and its influence on serum-related cytokines and immunoglobulins.
    Exp Ther Med 2018 Apr 15;15(4):3759-3764. Epub 2018 Feb 15.
    Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan 650000, P.R. China.
    The curative effect of minimally invasive surgery on palmar and foot hyperhidrosis and its influence on serum-related cytokines and immunoglobulins were investigated. Seventy-six patients with palmar and foot hyperhidrosis admitted to Yunnan University Hospital from August 2014 to July 2016 were selected and randomly divided into control group (n=38) and observation group (n=38) using a random number table. Patients in control group received drug therapy, while those in observation group underwent laparoscopic thoracic-4 sympathetic chain combined with thoracic-3 branch amputation. Read More

    Cardiorespiratory Side Effects in the Clipping Technique for the Treatment of Axillary and Palmar Hyperhidrosis.
    Arch Bronconeumol 2018 Mar 12. Epub 2018 Mar 12.
    Servicio de Cirugía Torácica, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, España; Servicio de Neumología, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, España.

    Asymptomatic loss of intraepidermal nerve fibers with preserved thermal detection thresholds after repeated exposure to severe cold.
    Brain Behav 2018 Mar 4;8(3):e009147. Epub 2018 Feb 4.
    Department of NeurologyOdense University HospitalOdense CDenmark.
    Background: Cold-induced peripheral neuropathy has been described in individuals exposed to severe cold resulting in pain, hypersensitivity to cold, hyperhidrosis, numbness, and skin changes. Nerve conduction studies and thermal detection thresholds are abnormal in symptomatic patients, and intraepidermal nerve fiber density (IENFD) in skin biopsies is reduced.

    Case Presentation: A 41-year-old male was included as a healthy subject in a study of the spontaneous variability of quantitative sensory testing (QST), nerve conduction studies (NCS), and IENFD. Read More

    Transcriptomic analysis of FUCA1 knockdown in keratinocytes reveals new insights in the pathogenesis of fucosidosis skin lesions.
    Exp Dermatol 2018 Mar 8. Epub 2018 Mar 8.
    Center For Research in Genetics and Genomics-CIGGUR. GENIUROS Research Group. School of Medicine and Health Sciences, Universidad del Rosario. Bogotá, Colombia.
    Fucosidosis is a rare lysosomal storage disease which has been classified into two subtypes, depending on the severity of clinical signs and symptoms. Fucosidosis patients' skin abnormalities include angiokeratoma corporis diffusum, widespread telangiectasia, thick skin, hyperhidrosis and hypohidrosis, acrocyanosis and distal transverse nail bands. It has been described that >50% of fucosidosis patients have angiokeratoma. Read More

    Lumbar sympathectomy can improve symptoms associated with ischaemia, vasculitis, diabetic neuropathy and hyperhidrosis affecting the lower extremities-a single-centre experience.
    Ir J Med Sci 2018 Mar 7. Epub 2018 Mar 7.
    Department of Vascular Surgery, Mercy University Hospital, Cork, Ireland.
    Background: Lumbar sympthectomy (LS) was traditionally performed for intermittent claudication but is now eclipsed by revascularisation for that indication. However, it retains a role in the management of critical limb ischaemia and other conditions causing lower limb pain with or without ischaemia. We report the role of LS in modern surgical practice when revascularisation and pain management options have been exhausted. Read More

    Results of a 10-year follow-up study of botulinum toxin A therapy for primary axillary hyperhidrosis in Australia.
    Intern Med J 2018 Mar;48(3):343-347
    Southern Suburbs Dermatology, Sydney, New South Wales, Australia.
    Primary hyperhidrosis has a prevalence of 3-5% in the United States. It is a psychosocially disabling condition leading to low self-esteem, chronic stress and depressive symptoms. Several medical and surgical treatments exist, including botulinum toxin A, which internationally, has been shown effectively and safely to treat this condition achieving high patient satisfaction. Read More

    Hyperhidrosis - Sweating Sites Matter: Quality of Life in Primary Hyperhidrosis according to the Sweating Sites Measured by SF-36.
    Dermatology 2017 2;233(6):441-445. Epub 2018 Mar 2.
    Department of Public Health and Clinical Medicine, Dermatology and Venereology, Umeå University, Umeå, Sweden.
    Background: Primary hyperhidrosis has negative impacts on quality of life. The aim of this study was to investigate whether the impacts of primary hyperhidrosis on quality of life are different depending on the localisation of the sweating.

    Method: We compiled background data, Hyperhidrosis Disease Severity Scale (HDSS), and Short-Form Health Survey (SF-36) post hoc results from 2 previous studies. Read More

    Versajet-Assisted Hydraulic Epilation Through Small Incisions for Axillary Osmidrosis.
    Aesthetic Plast Surg 2018 Feb 20. Epub 2018 Feb 20.
    Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul, 03181, Republic of Korea.
    Background: Osmidrosis is a malodorous disease caused by the breakdown of sweat secreted from the apocrine glands by surface bacteria. The aim of this study was to evaluate the effect of Versajet-assisted hydraulic epilation for the treatment of axillary osmidrosis.

    Methods: Thirty-two patients with axillary osmidrosis (64 axillae) underwent Versajet-assisted hydraulic epilation between January 2016 and January 2017. Read More

    Generalized hyperhidrosis secondary to presumed eccrine gland dysfunction with possible apocrine metaplasia.
    Dermatol Online J 2017 Dec 15;23(12). Epub 2017 Dec 15.
    New York University Health, New York.
    We present a 57 year-old man presented with generalized hyperhidrosis and widespread, smooth, flesh colored papules on the torso and extremities.Histological examination from multiple biopsies demonstrated morphologic alteration of the eccrine glands with an apocrine phenotype, suggesting eitherapocrine metaplasia or the presence of "apoeccrine glands." The morphologic similarities between eccrine, apocrine, and apoeccrine as they relate to ourpatient's histologic findings are discussed. Read More

    Extended uniportal bilateral sympathectomy.
    J Vis Surg 2018 30;4:27. Epub 2018 Jan 30.
    Section of Thoracic Surgery, Department of General and Medical Specialties, Policlinico University Hospital of Catania, University of Catania, Catania, Italy.
    Hyperhidrosis affect 3% of the population and, despite benign nature of the disease, the individuals seek medical advice in order to improve their quality of life which can be severely compromised. The interruption of the sympathetic chain (sympathectomy) and of the nerve of Kuntz established its role as the definitive treatment of primary hyperhidrosis. In this manuscript, we present our extended uniportal technique with the aid of the video. Read More

    The First Reported Case of Fibrous Hamartoma of Infancy with Hyperhidrosis and Hypertrichosis in Korea.
    J Korean Med Sci 2018 Feb 26;33(9):e66. Epub 2018 Feb 26.
    Department of Dermatology, Yeungnam University College of Medicine, Daegu, Korea.
    Fibrous hamartoma of infancy (FHI) is a rare entity with a benign nature. The typical clinical features are a single, slowly growing, painless mass on the trunk that appears within the first 2 years of life. We report a 13-month-old boy who presented with a plaque on the lower back since 4 months of age. Read More

    Alternative Surgical Methods in Patients with Recurrent Palmar Hyperhidrosis and Compensatory Hyperhidrosis.
    Yonsei Med J 2018 Mar;59(2):345-348
    Department of Thoracic and Cardiovascular Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
    Recurrent hyperhidrosis after thoracic sympathectomy is an uncomfortable condition, and compensatory hyperhidrosis (CH) is one of the most troublesome side effects. Here, we describe two patients with recurrent palmar hyperhidrosis (PH) and CH over the whole body simultaneously. They were treated with bilateral T4 sympathetic clipping and reconstruction of the sympathetic nerve from a T5 to T8 sympathetic nerve graft, which was transferred to the resected T3 sympathetic bed site. Read More

    Inguinal Hyperhidrosis: Case Report of an Uncommon Cause of Vaginitis.
    J Pediatr Adolesc Gynecol 2018 Feb 6. Epub 2018 Feb 6.
    Division of Pediatric and Adolescent Gynecology, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.
    Background: Hyperhidrosis (excessive sweating) affects 1%-3% of the population. Primary focal hyperhidrosis most commonly affects the axilla, palms, and soles. There are few case reports of hyperhidrosis of the genital region, typically described as inguinal hyperhidrosis or Hexsel's hyperhidrosis. Read More

    Two patients with localised hyperhidrosis of the hand based on functional and structural abnormalities of sweat glands.
    BMJ Case Rep 2018 Jan 31;2018. Epub 2018 Jan 31.
    Dermatology and Allergy Center, University Hospital of Odense, Odense, Denmark.
    A 14-year-old girl and a 30-year-old woman presented with localised hyperhidrosis on the dorsal hand and wrist, respectively, provoked by different stimuli such as physical activity and minor trauma to the skin. The skin was seemingly normal in both patients where an iodine-starch test revealed a well-demarcated area of hyperhidrosis. Following histopathological examination, the diagnosis was unilateral localised hyperhidrosis in both cases; one with normal histology and one with a nevus sudoriferous. Read More

    Severe dysautonomia as a main feature of anti-GAD encephalitis: Report of a paediatric case and literature review.
    Eur J Paediatr Neurol 2018 May 12;22(3):548-551. Epub 2018 Jan 12.
    Research Unit UR12 SP24 and Department of Child and Adolescent Neurology, National Institute Mongi Ben Hmida of Neurology, Tunis, Tunisia; Université de Tunis El Manar, Faculté de Médecine de Tunis, 1007, Tunis, Tunisia.
    Introduction: Anti-glutamic acid decarboxylase (anti-GAD65) antibodies are a rare cause of autoimmune encephalitis. This entity is mainly recognized in adults and very few cases were reported in children. We report on a paediatric case of anti-GAD encephalitis with severe presentation and uncontrollable dysautonomia. Read More

    Oxybutynin 3% gel for the treatment of primary focal hyperhidrosis in adolescents and young adults.
    Pediatr Dermatol 2018 Mar 15;35(2):208-212. Epub 2018 Jan 15.
    Department of Pediatrics, School of Medicine, University of Colorado, Aurora, CO, USA.
    Background/objectives: There are no reliably effective, well-tolerated topical agents for the treatment of hyperhidrosis. We sought to evaluate the efficacy and tolerability of oxybutynin 3% gel in adolescents and young adults with primary focal hyperhidrosis.

    Methods: Patients with severe axillary hyperhidrosis were treated with topical oxybutynin 3% gel for 4 weeks. Read More

    Laser treatment of primary axillary hyperhidrosis: a review of the literature.
    Lasers Med Sci 2018 Apr 11;33(3):675-681. Epub 2018 Jan 11.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Miami, FL, 33136, USA.
    Hyperhidrosis o`ccurs when the body produces sweat beyond what is essential to maintain thermal homeostasis. The condition tends to occur in areas marked by high-eccrine density such as the axillae, palms, and soles and less commonly in the craniofacial area. The current standard of care is topical aluminum chloride hexahydrate antiperspirant (10-20%), but other treatments such as anticholinergics, clonidine, propranolol, antiadrenergics, injections with attenuated botulinum toxin, microwave technology, and surgery have been therapeutically implicated as well. Read More

    Granulosis Rubra Nasi Response to Topical Tacrolimus.
    Case Rep Dermatol Med 2017 29;2017:2519814. Epub 2017 Nov 29.
    Department of Dermatology, Venereology & Leprosy, Jawaharlal Nehru Medical College and KLE's Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum, Karnataka 590 010, India.
    Granulosis Rubra Nasi (GRN) is a rare disorder of the eccrine glands. It is clinically characterized by hyperhidrosis of the central part of the face, most commonly on the tip of the nose, followed by appearance of diffuse erythema over the nose, cheeks, chin, and upper lip. It is commonly seen in childhood but it can present in adults. Read More

    Evaluation of topical liposome incorporated clove oil in the treatment of idiopathic palmar hyperhidrosis: Single-blinded placebo-controlled study.
    J Cosmet Dermatol 2017 Dec 28. Epub 2017 Dec 28.
    Department of Dermatology and Venerology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
    Introduction: Palmar hyperhidrosis is of great concern to patients because of its physical, occupational, and psychological impact on quality of life. Topical clove oil has been used in many conditions due to its major component Eugenol that exerts blocking effect on nerve transmission.

    Aim Of The Work: To assess the efficacy of topical liposome incorporated clove oil in decreasing the rate of sweating among patients with idiopathic palmar hyperhidrosis. Read More

    Synchronous bilateral pheochromocytomas and paraganglioma with novel germline mutation in MAX: a case report.
    Surg Case Rep 2017 Dec 28;3(1):131. Epub 2017 Dec 28.
    Department of Breast and Endocrine Surgery (Surgery II), Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
    Background: Recent advance of genetic testing has contributed to the diagnosis of hereditary pheochromocytoma and paraganglioma (PPGL). The clinical characteristics of hereditary PPGL are varying among the types of mutational genes. It is still difficult to specify the pathognomonic symptoms in the case of rare genetic mutations. Read More

    [Prevention and treatment of Horner syndrome in treatment of head and face hyperhidrosis by thoracic sympathetic nerve modulation].
    Zhonghua Yi Xue Za Zhi 2017 Dec;97(46):3624-3627
    Bengbu Medical College Graduate Department, Bengbu 233030, China.
    By summarize the Prevention and Treatment of Horner Syndrome of CT-guided thoracic sympathetic nerve modulation in the treatment of head and face Hyperhidrosis, reduce the occurrence of the complications. A retrospective analysis was made on 116 patients of CT-guided thoracic sympathetic nerve modulation in the treatment of head and face Hyperhidrosis in The First Hospital of Jiaxing from January 2010 to December 2016. Analysis the reasons of Horner syndrome and external management to sum up the corresponding prevention and treatment measures. Read More

    Interventions for hyperhidrosis in secondary care: a systematic review and value-of-information analysis.
    Health Technol Assess 2017 Dec;21(80):1-280
    Centre for Reviews and Dissemination, University of York, York, UK.
    Background: Hyperhidrosis is uncontrollable excessive sweating that occurs at rest, regardless of temperature. The symptoms of hyperhidrosis can significantly affect quality of life. The management of hyperhidrosis is uncertain and variable. Read More

    [Application of functional parotidectomy via retroauricular hairline incision in the excising superficial parotid tumor].
    Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Dec;52(12):905-908
    Department of Otorhinolaryngology Head and Neck Surgery, University of Hong Kong-Shenzhen Hospital, Shenzhen 518053, China;Division of Otorhinolaryngology Head and Neck Surgery, Department of Surgery, University of Hong Kong Li Ka Shing Faculty of Medicine, Hong Kong 999077, China.
    To evaluate the usefulness of retroauricular hairline incision (RAHI) in partial superficial parotidectomy (PSP) by comparison with modified Blair incision (MBI). A retrospective analysis of 64 medical records for patients with benign parotid tumors who underwent partial superficial parotidectomy was undertaken (28 were in MBI group, 36 in RAHI group). Size and location of tumors, operative time, occurrence of facial nerve paralysis and Frey's syndrome, and cosmetic outcomes were compared between RAHI and MBI groups. Read More

    The therapeutic effect of modified Huangqi Guizhi Wuwu Tang for multiple myeloma: An 18-year follow-up case report.
    Medicine (Baltimore) 2017 Dec;96(49):e9074
    aBasic Medicine CollegebInternational Jingfang Institute, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China.
    Rationale: Multiple myeloma (MM) is a hematologic malignancy characterized by proliferation of clonal plasma cells in the bone marrow. The median survival has increased to 6 years in recent years. But MM remains incurable. Read More

    Postmenopausal craniofacial hyperhidrosis.
    Clin Exp Dermatol 2018 Mar 13;43(2):180-182. Epub 2017 Dec 13.
    Department of Dermatology, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Broadgreen Hospital, Liverpool, UK.
    Hyperhidrosis is a condition marked by excessive sweating, which can either be localized or generalized. Primary focal hyperhidrosis (PFH) can arise from the palms, plantar feet, axillae and also from the face and scalp. PFH primarily affects a younger population of children and young adults, with the majority presenting before the age of 25 years. Read More

    Antidiabetic and Lipid-Lowering Effects of the Polyphenol Extracts from the Leaves of Clausena lansium (Lour.) Skeels on Streptozotocin-Induced Type 2 Diabetic Rats.
    J Food Sci 2018 Jan 11;83(1):212-220. Epub 2017 Dec 11.
    Coll. of Pharmacy, Guangdong Pharmaceutical Univ., Guangzhou 510006, China.
    Clausena lansium (Lour.) Skeels (Wampee) is widely grown in China and considered as a healthy fruit. Its leaves are also considered as traditional herbs. Read More

    Is compensatory hyperhidrosis after thoracic sympathicotomy in palmar hyperhidrosis patients related to the excitability of thoracic sympathetic ganglions?
    J Thorac Dis 2017 Sep;9(9):3069-3075
    Department of Thoracic Surgery, Xiamen Hospital of Traditional Chinese Medicine, Xiamen 361000, China.
    Background: The mechanism of compensatory hyperhidrosis remains unclear. The aim of this study was to explore the relationship between compensatory hyperhidrosis and thoracic sympathetic ganglion excitability to assess the effectiveness of thoracoscopic T4 sympathicotomy for treating palmar hyperhidrosis.

    Methods: Sixty-six cases of T4 sympathetic ganglions were prospectively collected from patients with palmar hyperhidrosis who underwent thoracoscopic T4 sympathicotomy from 2013 to 2016 in our department. Read More

    Survival study of treatment adherence by patients given oral oxibutynin for hyperhidrosis.
    J Eur Acad Dermatol Venereol 2017 Dec 8. Epub 2017 Dec 8.
    Dermatology Department, Hospital Costa del Sol, Marbella, Málaga, Spain.
    Introduction: In recent years, increasing use has been made of oral anticholinergics such as oxybutynin for the management of hyperhidrosis. The primary aim of this study is to determine the variables associated with adherence to this treatment, and secondarily to obtain data on its effectiveness, safety and adverse effects.

    Material And Methods: This is a prospective study of patients with hyperhidrosis, at any location, receiving treatment with oral oxybutynin in the period 2007-2016. Read More

    Polyarthritis is a Rare Manifestation of Pachydermoperiostosis: A Case Report.
    Mymensingh Med J 2017 Oct;26(4):939-943
    Dr Md Faysal Ahmmed, Resident, Department of Rheumatology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
    Pachydermoperiostosis or primary hypertrophic osteoarthropathy, also known as Touraine-Solente-Gole syndrome, is a rare process, frequently inherited. In its complete form it is characterized by pachydermia (thickening of the skin), skeletal changes (periostosis) and acropachia (digital clubbing). Diagnosis can be made considering the typical clinical features and the histological feature. Read More

    Pulsed radiofrequency stimulation suppresses palmar hyperhidrosis in an animal study.
    Brain Behav 2017 Nov 26;7(11):e00833. Epub 2017 Sep 26.
    Department of Veterinary MedicineSchool of Veterinary MedicineNational Taiwan UniversityTaipeiTaiwan.
    Objectives: Palmar hyperhidrosis (PH) exhibits excessive and unpredictable sweating. The most effective treatment for permanent cure is the ablation of thoracic sympathetic ganglia innervating hands. However, sympathectomy of T2 sympathetic ganglion by clipping or cauterization causes irreversible nerve damage, and results in a compensatory hyperhidrosis (CH). Read More

    Treatment of Palmar Hyperhidrosis with Tap Water Iontophoresis: A Randomized, Sham-Controlled, Single-Blind, and Parallel-Designed Clinical Trial.
    Ann Dermatol 2017 Dec 30;29(6):728-734. Epub 2017 Oct 30.
    Department of Dermatology, Dongguk University Ilsan Hospital, Goyang, Korea.
    Background: Palmar hyperhidrosis is a common disorder of excessive sweating. A number of studies have demonstrated the effectiveness of iontophoresis in the treatment of palmar hyperhidrosis. However, controlled clinical studies on iontophoresis for palmar hyperhidrosis have been limited. Read More

    [Aripiprazole-Induced Hyperhidrosis: Two Case Reports].
    Turk Psikiyatri Derg 2017 ;28(2):132-134
    Many drugs including anti-depressants and anti-psychotics are known to cause excessive sweating (hyperhidrosis). Hyperhidrosis may be caused by drugs acting at the hypothalamus, spinal thermoregulatory centres, and sympathetic ganglia or at the eccrine-neuroeffector junction. Hyperhidrosis can be distressing and embarrassing symptom, which if not addressed properly, may lead to non-concordance to medication. Read More

    Dermatologic manifestations of endocrine disorders.
    Transl Pediatr 2017 Oct;6(4):300-312
    The Ohio State University College of Medicine, Columbus, OH, USA.
    The skin serves as a window for clinicians to understand, diagnose, and monitor endocrine disease. Dermatologic manifestations of endocrinopathies contribute significantly to an individual's health and quality of life. In this review, we outline various disorders of the hypothalamic-pituitary axis, thyroid gland, pancreas, adrenal gland, and androgen axis as well as hereditary endocrine syndromes. Read More

    Phase IIIb safety results from an expanded-access protocol of talimogene laherparepvec for patients with unresected, stage IIIB-IVM1c melanoma.
    Melanoma Res 2018 Feb;28(1):44-51
    Department of Hematology and Oncology, Minnesota Oncology, Fridley, Minnesota.
    Talimogene laherparepvec is a genetically modified herpes simplex virus-1-based oncolytic immunotherapy for the local treatment of unresectable cutaneous, subcutaneous, and nodal tumors in patients with melanoma recurrence following surgery. We aim to describe the safety of talimogene laherparepvec. Intralesional talimogene laherparepvec was administered at less than or equal to 4 ml×10 PFU/ml at protocol day 1, then less than or equal to 4 ml×10 PFU/ml 21 days later, and then every 14 days. Read More

    [Palmar and axillary hyperhidrosis in children: endoscopic thoracic sympathectomy using clips for an underestimated problem].
    Ned Tijdschr Geneeskd 2017 ;161(0):D1615
    Albert Schweitzer ziekenhuis, Dordrecht.
    Background: Palmar and axillary hyperhidrosis are defined as perspiration exceeding the body's 'normal' physiological need for thermal regulation. This condition affects about 1% of adolescents and children and may lead to psychosocial problems and poor school performance.

    Case Description: We carried out an endoscopic thoracic sympathectomy (ETS) with clips in a 14-year-old girl and a 16-year-old girl who suffered from debilitating palmar and axillary hyperhidrosis. Read More

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