4,593 results match your criteria Hyperhidrosis


Exploring hyperhidrosis and related thermoregulatory symptoms as a possible clinical identifier for the dysautonomic subtype of Parkinson's disease.

J Neurol 2019 Apr 17. Epub 2019 Apr 17.

King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neurosciences, De Crespigny Park, London, SE5 8AF, UK.

Objective: To identify associated (non-)motor profiles of Parkinson's disease (PD) patients with hyperhidrosis as a dominant problem.

Methods: This is a cross-sectional, exploratory, analysis of participants enrolled in the Non-motor Longitudinal International Study (NILS; UKCRN No: 10084) at the Parkinson's Centre at King's College Hospital (London, UK). Hyperhidrosis scores (yes/no) on question 28 of the Non-Motor Symptom Questionnaire were used to classify patients with normal sweat function (n = 172) and excessive sweating (n = 56) (Analysis 1; n = 228). Read More

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http://dx.doi.org/10.1007/s00415-019-09325-wDOI Listing
April 2019
1 Read

Establishing a non-intubated thoracoscopic surgery programme for bilateral uniportal sympathectomy.

Swiss Med Wkly 2019 Apr 17;149:w20064. Epub 2019 Apr 17.

Department of Thoracic Surgery, University Hospital Zurich, Switzerland.

Aim Of The Study: Non-intubated, video-assisted thoracoscopic surgery (NiVATS) has been successfully developed in several centres worldwide. Local anaesthesia techniques and techniques to perform thoracoscopic surgery on a spontaneously breathing lung are the two key elements which must be adopted to establish a NiVATS programme. We established NiVATS by performing bilateral, uniportal sympathectomies, and compared it to classical video-assisted thoracoscopic surgery (VATS) under general anaesthesia with double-lumen intubation. Read More

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http://dx.doi.org/10.4414/smw.2019.20064DOI Listing
April 2019
1 Read

A Comparison of Patient Reported Disease Severity and Sweat Measurements in Primary Focal Hyperhidrosis.

J Am Acad Dermatol 2019 Apr 12. Epub 2019 Apr 12.

Professor, Interim Chair, Department of Dermatology, Saint Louis University.

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http://dx.doi.org/10.1016/j.jaad.2019.04.015DOI Listing

Hyperhidrosis and Dysautonomia in a Patient with a History of Tetraplegia following Cervical Facet Radiofrequency Ablation: A Case Report.

PM R 2019 Apr 15. Epub 2019 Apr 15.

UC San Diego Health Center, Department of Anesthesia, Pain medicine.

Chronic pain in those with spinal cord injury (SCI) can significantly impact quality of life, with prevalence ranging from 26%-96% . Treatment of chronic pain is notoriously challenging and unsatisfactory for providers and patients . Patients with traumatic SCI and fusion can develop adjacent-level degeneration . Read More

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http://dx.doi.org/10.1002/pmrj.12168DOI Listing

Indurated Dusky Red Swelling on the Forearm of an Infant: Tufted Angioma.

Indian J Dermatol 2019 Mar-Apr;64(2):146-148

Department of Pathology, University College of Medical Sciences and GTB Hospital (University of Delhi), New Delhi, India.

Tufted angioma (TA) is a rare benign vascular tumor that may be congenital or acquired and generally presents as an asymptomatic or painful solitary erythematous to violaceous poorly defined plaque. Hyperhidrosis and hypertrichosis may be associated. The lesions have tendency to resolve spontaneously, in majority, within 2 years of disease onset. Read More

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http://dx.doi.org/10.4103/ijd.IJD_468_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440174PMC

Integrated transcriptomic and proteomic analysis of human eccrine sweat glands identifies missing and novel proteins.

Mol Cell Proteomics 2019 Apr 12. Epub 2019 Apr 12.

Laboratory Medicine and Pathology, Mayo Clinic, United States of America

The eccrine sweat gland is an exocrine gland that is involved in the secretion of sweat for control of temperature. Malfunction of the sweat glands can result in disorders such as miliaria, hyperhidrosis and bromhidrosis. Understanding the transcriptome and proteome of sweat glands is important for understanding their physiology and role in diseases. Read More

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http://www.mcponline.org/lookup/doi/10.1074/mcp.RA118.001101
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http://dx.doi.org/10.1074/mcp.RA118.001101DOI Listing
April 2019
3 Reads

Glycopyrronium Tosylate (Qbrexza) for Hyperhidrosis

Skin Therapy Lett 2019 Mar;24(2):1-3

Department of Dermatology, McGovern Medical School, The University of Texas Health Sciences Center, Houston, TX, USA

Hyperhidrosis is a condition characterized by excessive sweat production beyond which is physiologically necessary for thermal regulation. Affecting over 4.8% of the United States population, studies have shown that severe primary hyperhidrosis interferes with daily activities and can be considered intolerable, negatively impacting a patient’s quality of life. Read More

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March 2019
1 Read

Analysis of Contact Position for Subthalamic Nucleus Deep Brain Stimulation-Induced Hyperhidrosis.

Parkinsons Dis 2019 6;2019:8180123. Epub 2019 Mar 6.

Department of Neurosurgery, Second Military Medical University, Changhai Hospital, No. 168 Changhai Road, Yangpu District, Shanghai, China.

Objectives: To analyze the hyperhidrosis neural network structure induced by subthalamic nucleus (STN) - deep brain stimulation (DBS).

Materials And Methods: Patients with Parkinson's disease treated with STN-DBS in Changhai Hospital between July 1, 2015, and December 1, 2016, were analyzed retrospectively. Using records of side effects of the intraoperative macrostimulation test, patients with skin sweats were selected as the sweating group. Read More

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http://dx.doi.org/10.1155/2019/8180123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431408PMC
March 2019
1 Read

[Spanish validation of the Autonomic Standards Assessment Form in spinal cord injuries].

Rehabilitacion (Madr) 2019 Jan - Mar;53(1):20-27. Epub 2018 Dec 7.

Unidad de Lesionados Medulares, Área de Rehabilitación, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, Barcelona, España.

Introduction And Objectives: Autonomic nervous system (ANS) dysfunction in patients with spinal cord injury (SCI) severely impacts morbidity and mortality. However, research initiatives aiming to gain insight into the direct impact of ANS dysfunction on health outcomes in persons with SCI are still lacking. Thus, this study had 2main objectives: 1) to translate into Spanish the revised edition of the International Standards on documentation of remaining Autonomic Function after SCI (ISAFSCI), and 2) to describe the impact of ANS dysfunction in a sample of SCI patients. Read More

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http://dx.doi.org/10.1016/j.rh.2018.10.007DOI Listing
December 2018
2 Reads

Angiocentric Centrofacial Lymphoma as a Challenging Diagnosis in an Elderly Man.

Am J Case Rep 2019 Mar 30;20:412-418. Epub 2019 Mar 30.

School of Medicine and Health Sciences, Tecnologico de Monterrey, Guadalajara, Jalisco, Mexico.

BACKGROUND Angiocentric centrofacial lymphomas, now known as nasal-type extranodal natural killer T-cell lymphomas, are neoplasms of highly destructive characteristics that mainly affect the nasal cavity and palate. The most frequent clinical presentation includes fever, weight loss, nasal obstruction, epistaxis, nasal or facial edema, as well as necrotic ulcers in the nasal cavity, gums, and palate. It has been found to have an important association with the Epstein-Barr virus. Read More

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https://www.amjcaserep.com/abstract/index/idArt/913856
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http://dx.doi.org/10.12659/AJCR.913856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454582PMC
March 2019
2 Reads

Takotsubo cardiomyopathy associated with serotonin syndrome in a patient with stroke: A case report.

Medicine (Baltimore) 2019 Mar;98(13):e15057

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daemyungdong, Namku, Taegu, Republic of Korea.

Rationale: Takotsubo cardiomyopathy (TC) is characterized by transient left ventricular dysfunction. We describe a patient with stroke who presented with TC caused by serotonin syndrome (SS) following the administration of serotonergic and dopaminergic agents.

Patient Concerns: A 55-year-old man with stroke was administered venlafaxine, tianeptine, ropinirole, carbidopa/levodopa, bromocriptine, and methylphenidate during rehabilitation. Read More

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http://dx.doi.org/10.1097/MD.0000000000015057DOI Listing
March 2019
3 Reads

Bilateral Eccrine Angiomatous Hamartoma with Symmetric Volar Wrist Nodules: A Case Report.

JBJS Case Connect 2019 Jan-Mar;9(1):e20

Departments of Orthopaedic Surgery and Pathology, and the Division of Pediatric Dermatology, Departments of Pediatrics and Dermatology, The Johns Hopkins University, Baltimore, Maryland.

Case: We describe a 13-year-old girl with bilateral symmetric eccrine angiomatous hamartoma (EAH) on the volar aspect of the wrists. The lesions were painless and had been enlarging progressively for 1 year; the enlargement of the nodule on the right wrist was more substantial than that on the left wrist. She had palmar hyperhidrosis, which has a known association with EAH. Read More

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http://dx.doi.org/10.2106/JBJS.CC.18.00230DOI Listing

A novel anesthetic technique for palmar botulinum toxin injections: novel but no anesthetic.

J Am Acad Dermatol 2019 Mar 21. Epub 2019 Mar 21.

Infinity Family Medicine Clinic, The Village Mall, Jumeirah Beach Road, P.O. Box 215428, Dubai, UAE. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2019.02.069DOI Listing

Pharmacology, toxicology and clinical safety of glycopyrrolate.

Toxicol Appl Pharmacol 2019 May 21;370:154-169. Epub 2019 Mar 21.

Dr. August Wolff GmbH & Co. KG Arzneimittel, Bielefeld, Germany.

The clinical use of the anticholinergic glycopyrrolate dates back to the early 1960s when it was first approved in the U.S. Since then, oral and inhalation formulations have been developed as therapeutic agents inhibiting the muscarinic acetylcholine receptor in various indications including chronic obstructive pulmonary disease (COPD), excessive salivation, and peptic ulcers. Read More

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http://dx.doi.org/10.1016/j.taap.2019.03.016DOI Listing
May 2019
1 Read

Intramedullary Spinal Cord Ganglioglioma Presenting as Hyperhidrosis: A Rare Case Report and literature Review.

World Neurosurg 2019 Mar 20. Epub 2019 Mar 20.

Departments of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. Electronic address:

Background: Hyperhidrosis is caused by sympathetic dysfunction of the central or peripheral nervous system. However, intramedullary spinal cord tumors presenting with hyperhidrosis as an initial symptom had been rarely reported in the literature.

Case Description: This case involves an 18-year-old man who presented with abnormal enhanced sweating and flushing on the bilateral side of his face and neck that had persisted for 6 years. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.115DOI Listing
March 2019
1 Read

Radiofrequency Therapy and Noncosmetic Cutaneous Conditions.

Dermatol Surg 2019 Mar 18. Epub 2019 Mar 18.

Department of Dermatology, University of California, Irvine, Irvine, California.

Background: The need for noninvasive methods in treatment of cutaneous disease has continued to evolve exponentially. Amidst the search for technologies, radiofrequency (RF) has proven efficacious in numerous skin disease processes. Although RF is well known for its cosmetic utility, its mechanism is valued in the treatment of many noncosmetic cutaneous conditions of various etiologies. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001925DOI Listing
March 2019
9 Reads

Beta-mannosidosis caused by a novel homozygous intragenic inverted duplication in MANBA.

Cold Spring Harb Mol Case Stud 2019 Mar 18. Epub 2019 Mar 18.

Institute of Biomedicine, Sahlgrenska Academy, Gothenburg University.

Beta-mannosidosis is a lysosomal storage disorder characterized by accumulation of disaccharides due to deficiency of the lysosomal enzyme beta-mannosidase. The disease is caused by mutations in MANBA and is extremely rare in humans. Although the clinical presentation is heterogeneous, common symptoms include various degrees of developmental delay, behavioral disturbances, hearing loss and frequent infections. Read More

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http://dx.doi.org/10.1101/mcs.a003954DOI Listing
March 2019
2 Reads

Rare Complication of Botox Injection: A Case Report.

World J Plast Surg 2019 Jan;8(1):116-119

Department of Surgery, Iran University of Medical Science, Tehran, Iran.

Botulinum toxin (BTX) is also well-known as Botox is produced by a gram-positive anaerobic bacterium called Generally, clinical manifestations of BTX can be observed after consumption of contaminated food, from colonization of the infant gastrointestinal tract, as well as following the infection of the wound to this bacterium. There are seven types of this neurotoxin labeled as A, B, C (C1, C2), D, E, and F. Human botulinum is caused by types A, B, E and rarely F. Read More

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http://dx.doi.org/10.29252/wjps.8.1.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409137PMC
January 2019
7 Reads

A case of acromegaly caused by Rathke's cleft cyst mimicking a plurihormonal pituitary adenoma.

World Neurosurg 2019 Mar 9. Epub 2019 Mar 9.

Department of Neurosurgery, Fukuoka University Chikushi Hospital, Chikushino-city, Japan.

Background: Acromegaly caused by Rathke's cleft cyst (RCC) mimicking a plurihormonal pituitary adenoma (PA) is rare.

Case Description: We report a 71-year-old woman who presented with hyperhidrosis in 2013. Magnetic resonance imaging (MRI) performed in April 2018 revealed that the patient had a pituitary tumor, and she was referred to our hospital. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.163DOI Listing
March 2019
2 Reads

Dyshidrosis associated with diabetes mellitus: Hypohidrosis associated with diabetic neuropathy and compensated hyperhidrosis.

J Dermatol 2019 Mar 12. Epub 2019 Mar 12.

Department of Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.14840DOI Listing
March 2019
3 Reads

Does clip removal help for compensatory hyperhidrosis complicating thoracic sympathetic clipping?

Clin Auton Res 2019 Mar 11. Epub 2019 Mar 11.

Department of Anesthesiology and Reanimation, Bakirkoy Research and Training Hospital, Istanbul, Turkey.

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http://dx.doi.org/10.1007/s10286-019-00599-8DOI Listing

Qbrexza - A glycopyrronium cloth for axillary hyperhidrosis.

Authors:

Med Lett Drugs Ther 2019 Jan;61(1564):10-11

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January 2019
2 Reads

Efficacy and Safety of Botulinum Toxin A in Axillary Bromhidrosis and Associated Histological Changes in Sweat Glands: A Prospective Randomized Double-Blind Side-by-Side Comparison Clinical Study.

Dermatol Surg 2019 Feb 28. Epub 2019 Feb 28.

Division of Plastic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Background: The efficacy of botulinum toxin A (BTX-A) therapy in axillary hyperhidrosis has been documented; however, there are a few studies reporting the efficacy of BTX-A in treating axillary bromhidrosis. The histological changes occurring in sweat glands after BTX-A treatment are also unknown.

Objective: The authors report on the efficacy and safety of BTX-A in the treatment of axillary bromhidrosis and on the histological changes in sweat glands after BTX-A treatment. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001906DOI Listing
February 2019
2.109 Impact Factor

The Treatment of Primary Focal Hyperhidrosis

Skin Therapy Lett 2019 01;24(1):1-7

Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC, USA

Primary focal hyperhidrosis is a relatively common disease that has a significant impact on afflicted patient’s quality of life. The pathogenesis of the disease is thought to stem from increased cholinergic activity on eccrine sweat glands. Topical aluminum chloride based antiperspirants are good first-line agents for all affected body sites. Read More

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January 2019
12 Reads

Clinical and histological evaluation of a single high energy microwave treatment for primary axillary hyperhidrosis in Asians: A prospective, randomized, controlled, split-area comparative trial.

Lasers Surg Med 2019 Feb 27. Epub 2019 Feb 27.

Department of Dermatology, Wakayama Medical University, Wakayama, Japan.

Background And Objectives: Microwave treatment is an effective non-invasive treatment option for primary axillary hyperhidrosis (PAH), but the treatment parameters vary and no histopathological studies have been performed to validate clinical outcomes. This study investigated its efficacy and safety and histopathological changes after a single microwave treatment at the maximum energy level for PAH in Asians.

Materials And Methods: A prospective, clinical, and histological split-area randomized controlled trial (RCT) was performed in Japan. Read More

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http://dx.doi.org/10.1002/lsm.23073DOI Listing
February 2019
2 Reads

[Impact of Selective Quality of Life Analysis in Patients with Local Hyperhidrosis after Sympathicus Clipping].

Zentralbl Chir 2019 Apr 22;144(2):139-145. Epub 2019 Feb 22.

Thoraxchirurgische Abteilung in der Chirurgischen Klinik, Universitätsklinikum, Friedrich-Alexander-Universität Erlangen-Nürnberg, Deutschland.

Introduction: Hyperhidrosis (HH) is associated with physical and psychological restrictions. The treatment includes both conservative and surgical methods and aims to permanently improve the quality of life (QoL) of those affected. Endoscopic sympathetic blockade (ESB) is an established surgical therapeutic method and is considered effective when conservative treatment options fail. Read More

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http://dx.doi.org/10.1055/a-0808-5003DOI Listing
April 2019
1 Read

Pachydermoperiostosis (Touraine-Solente-Gole syndrome): a case report.

J Med Case Rep 2019 Feb 21;13(1):39. Epub 2019 Feb 21.

Tribhuvan University Institute of Medicine, Maharajgunj, Kathmandu, Nepal.

Background: Pachydermoperiostosis (PDP) is a rare disorder characterized by clubbing of the fingers, thickening of the skin (pachyderma), and excessive sweating (hyperhidrosis). It typically appears during childhood or adolescence, often around the time of puberty, and progresses slowly. Clinical presentations of PDP can be confused with secondary hypertrophic osteoarthropathy, psoriatic arthritis, rheumatoid arthritis, thyroid acropachy, and acromegaly. Read More

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http://dx.doi.org/10.1186/s13256-018-1961-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383214PMC
February 2019
1 Read

Hyperhidrotic Macrodactylism Caused by Osteoid Osteoma: A Case Report and Review of the Literature.

J Foot Ankle Surg 2019 Feb 8. Epub 2019 Feb 8.

Professor, Department of Orthopedics, The First Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China. Electronic address:

Macrodactylism or macrodactyly is referred to as congenital deformity of fingers or toes, and the corresponding incidence rate is relatively low. In this article, we describe a young male with macrodactylism of the second toe of his right foot. He was suffering from persistent pain, overgrowth, and hyperhidrosis of the involved toe. Read More

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http://dx.doi.org/10.1053/j.jfas.2018.09.008DOI Listing
February 2019
5 Reads

Longitudinal follow-up of cardiac vagal activity in individuals undergoing endoscopic thoracic sympathectomy.

J Bras Pneumol 2018 Nov-Dec;44(6):456-460

. Programa de Pós-Graduação Strictu Sensu, Universidade do Estado do Rio de Janeiro - UERJ - Rio de Janeiro (RJ) Brasil.

Objective: To conduct a longitudinal investigation of cardiac vagal activity (CVA) by measuring resting HR and calculating the cardiac vagal index (CVI) in individuals undergoing sympathectomy for the treatment of primary hyperhidrosis.

Methods: This was a descriptive longitudinal study involving 22 patients, 13 of whom were female. The mean age was 22. Read More

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http://dx.doi.org/10.1590/S1806-37562017000000464DOI Listing

Using gauze to evenly spread starch for hyperhidrosis testing.

J Am Acad Dermatol 2019 Jan 30. Epub 2019 Jan 30.

Division of Dermatology, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2019.01.058DOI Listing
January 2019

The Etiology, Diagnosis and Management of Hyperhidrosis: A Comprehensive Review. Part I. Etiology and Clinical Work-Up.

J Am Acad Dermatol 2019 Jan 30. Epub 2019 Jan 30.

Rutgers- Robert Wood Johnson Medical School, Department of Dermatology, 1 World's Fair Drive, Suite 2400, Somerset, NJ 08873.

Hyperhidrosis (HH) is a dermatologic disorder defined by sweat production beyond the thermoregulatory requirements. Clinically, HH is diagnosed when excess sweating creates significant emotional, physical, or social discomfort, causing negative impact on the patient's quality of life. Existing data imply that this condition may affect at least 4. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.12.071DOI Listing
January 2019

The Etiology, Diagnosis and Management of Hyperhidrosis: A Comprehensive Review. Part II. Therapeutic Options.

J Am Acad Dermatol 2019 Jan 30. Epub 2019 Jan 30.

Rutgers- Robert Wood Johnson Medical School, Department of Dermatology, 1 World's Fair Drive, Suite 2400, Somerset, NJ 08873.

Hyperhidrosis (HH) is a chronic disorder of excess sweat production that may have a significant adverse effect on quality of life. A variety of treatment modalities currently exist to manage HH. Initial treatment includes lifestyle and behavioral recommendations. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.11.066DOI Listing
January 2019
8 Reads

Bilateral brachial plexus injury after MiraDry® procedure for axillary hyperhidrosis: a case report.

World Neurosurg 2019 Jan 28. Epub 2019 Jan 28.

Department of Orthopedic Surgery. Electronic address:

Multiple treatments are available for primary axillary hyperhidrosis, including non-invasive, microwave based thermal treatments designed to destroy sweat glands in the axilla. Often these procedures involve local anesthetic injection to the axilla, followed by placement of the microwave emitter onto the skin and applying the heat treatment to varying depths of the subcutaneous tissues. CASE REPORT: A 49-year old, thin and active woman (BMI 19. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.093DOI Listing
January 2019
2 Reads

The quality of life and satisfaction rate of patients with upper limb hyperhidrosis before and after bilateral endoscopic thoracic sympathectomy.

Saudi J Anaesth 2019 Jan-Mar;13(1):16-22

Department of Surgery, Thoracic Surgery Division, College of Medicine, King Saud University, King Khalid University Hospital, Riyadh, Saudi Arabia.

Background: Hyperhidrosis is a functional disorder identified by excessive sweating. Its incidence is approximately 1% in any population. Bilateral endoscopic thoracic sympathectomy (BETS) intervention is the definitive treatment of choice for palmar and axillary hyperhidrosis. Read More

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http://dx.doi.org/10.4103/sja.SJA_335_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329233PMC
January 2019
9 Reads

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy.

J Vis Exp 2019 Jan 10(143). Epub 2019 Jan 10.

Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital; Wound Healing Center, Peking University Third Hospital.

Chemical lumbar sympathectomy (CLS) is a commonly used, minimally invasive procedure for the treatment of conditions including ischemic diseases of the lower extremities, hyperhidrosis, etc. It is commonly practiced to position the puncture needle tip in front of the anterior fascia of the psoas major muscle and inject the inactivating agent around the sympathetic trunk, which is defined as conventional CLS. Although relatively rare, ureteropelvic damage is the most frequently reported complication of conventional CLS and can cause serious harm to patients. Read More

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http://dx.doi.org/10.3791/58894DOI Listing
January 2019
1 Read

Effectiveness of bilateral clipping of the thoracic sympathetic chain for the treatment of severe palmar and/or axillary hyperhidrosis and facial flushing.

Cir Esp 2019 Apr 23;97(4):196-202. Epub 2019 Jan 23.

Cirugía Torácica, Hospital Universitari Sagrat Cor, Barcelona, España; Cirugía Torácica, Hospital Clínic, Universitat de Barcelona, Barcelona, España.

Introduction: Division of the thoracic sympathetic chain is the standard treatment for severe palmar and/or axillary hyperhidrosis and facial flushing. Clipping is an alternative option which allows the block to be reverted in cases of intolerable compensatory sweating.

Methods: This is a prospective study performed to assess: a) results of clipping of the thoracic sympathetic chain in patients with palmar and/or axillary hyperhidrosis and facial flushing; and b) to determine the improvement obtained after removal of the clip in patients with unbearable compensatory sweating. Read More

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http://dx.doi.org/10.1016/j.ciresp.2018.11.009DOI Listing
April 2019
1 Read

The Association between Obesity and Hyperhidrosis: A Nationwide, Cross Sectional Study of 2.77 Million Israeli Adolescents.

J Am Acad Dermatol 2019 Jan 21. Epub 2019 Jan 21.

The Israel Defense Forces Medical Corps, Tel Hashomer, Ramat Gan, Israel; Sackler School of Medicine, Tel-Aviv University, Israel; Department of Military Medicine, Hebrew University, Jerusalem, Israel; Department of Medicine and the Dr. Pinchas Bornstein Talpiot Medical Leadership Program, Sheba Medical Center, Tel Hashomer, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2019.01.019DOI Listing
January 2019
1 Read

Topical Treatment of Primary Focal Hyperhidrosis, Part 1.

Authors:
Eyal Zur

Int J Pharm Compd 2019 Jan-Feb;23(1):23-31

Compounding Pharmacist, Israel.

Primary focal hyperhidrosis is idiopathic, localized, uncontrollable, excessive, and unpredictable sweating beyond what is necessary to regulate body temperature. Primary hyperhidrosis is thought to affect approximately 2% to 3% of the population, and its effect on a patient's quality of life is very significant. Primary focal hyperhidrosis can be managed using various therapeutic options, including drugs (topical and systemic), nonsurgical interventions (e. Read More

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January 2019
4 Reads

Clinical profile of recurrent vesicular palmoplantar dermatitis in children and adolescents.

Clin Cosmet Investig Dermatol 2019 3;12:23-28. Epub 2019 Jan 3.

Sector of Dermatology, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Background: Previously known as dyshidrosis, recurrent vesicular palmoplantar dermatitis (RVPD) is presented as severe eruption of nonerythematous, symmetrical vesicles or bullae located along the lateral sides of fingers, on the palmar or plantar areas, and developing into a chronic and recurrent condition. Although very frequently observed on the hands, there are no specific studies about such eczema in children and adolescents.

Objectives: To report on the RVPD clinical profile in children and adolescents, and monitor the association of RVPD with seasonal variations, hyperhidrosis, atopy and nickel sulfate. Read More

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http://dx.doi.org/10.2147/CCID.S150778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322509PMC
January 2019
3 Reads

A Retrospective Analysis of the use of Tap Water Iontophoresis for Focal Hyperhidrosis at a District General Hospital: The Patients' Perspective.

J Dermatolog Treat 2019 Jan 16:1-9. Epub 2019 Jan 16.

a Dermatology Department , Croydon University Hospital , Surrey , UK.

Tap water iontophoresis as a treatment for focal hyperhidrosis, is given as an initial series of treatments in hospital followed by home maintenance treatments. Our study assessed quality of life and perception of hyperhidrosis with the use of iontophoresis. All patients treated with iontophoresis at our hospital from 2012 - 2017 were retrospectively assessed (n = 82, mean age 34 years; 60% female). Read More

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http://dx.doi.org/10.1080/09546634.2019.1569751DOI Listing
January 2019
6 Reads

Pourfour du Petit Syndrome: A Rare Association With Cluster Headache.

Ophthalmic Plast Reconstr Surg 2019 Jan/Feb;35(1):e15-e16

Department of Ophthalmology, Nîmes University Hospital, Nîmes Cedex 9.

Pourfour du Petit syndrome is an uncommon cause of eyelid retraction, associated with unilateral mydriasis and hemifacial hyperhidrosis. This syndrome is caused by hyperactivity of the ipsilateral oculosympathetic pathway and needs to be recognized because it has an opposite clinical presentation but the same topographic and diagnostic value as Horner syndrome. The authors report a rare case of Pourfour du Petit syndrome associated with cluster headache and discuss pathophysiological hypotheses, clinical presentation, complementary exams, pharmacologic testing, treatment options, and prognosis. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001281DOI Listing
January 2019
3 Reads

Autonomic dysfunction in Parkinson disease and animal models.

Clin Auton Res 2019 Jan 2. Epub 2019 Jan 2.

Preclinical Parkinson's Research Program, Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.

Parkinson disease has traditionally been classified as a movement disorder, despite patients' accounts of diverse symptoms stemming from impairments in numerous body systems. Today, Parkinson disease is increasingly recognized by clinicians and scientists as a complex neurodegenerative disorder featuring both motor and nonmotor manifestations concomitant with pathology throughout all major branches of the nervous system. Dysfunction of the autonomic nervous system, or dysautonomia, is a common feature of Parkinson disease. Read More

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http://link.springer.com/10.1007/s10286-018-00584-7
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http://dx.doi.org/10.1007/s10286-018-00584-7DOI Listing
January 2019
4 Reads

Examining hyperhidrosis: an update on new treatments.

Authors:
Carolyn I Jacob

Am J Manag Care 2018 Dec;24(23 Suppl):S496-S501

Director, Chicago Cosmetic Surgery and Dermatology; affiliate clinical instructor, Northwestern University Feinberg School of Medicine, Chicago, IL. Email:

Primary hyperhidrosis is a debilitating condition that causes significant distress and financial burden for affected patients, triggering them to seek medical care for their excessive sweating. Once a diagnosis of primary hyperhidrosis has been established, treatment is initiated to help control sweat production and increase quality of life. While there are no current guidelines in the United States for the treatment of primary hyperhidrosis, there are International Hyperhidrosis Society guidelines that clinicians can use. Read More

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December 2018
15 Reads

Hyperhidrosis and its impact on those living with it.

Am J Manag Care 2018 Dec;24(23 Suppl):S491-S495

Department of Dermatology, Emory University School of Medicine, Atlanta, GA. Email:

Sweating plays a vital role for humans. However, excessive sweating, also called hyperhidrosis, is a condition resulting in sweating beyond what is physiologically necessary. The increased rate of sweating is not caused by external stimuli or temperature fluctuations, as with an individual without hyperhidrosis. Read More

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December 2018
14 Reads

[Nagashima-type palmoplantar keratoderma: A little-known palmoplantar keratoderma in Europe].

Ann Dermatol Venereol 2019 Feb 21;146(2):125-130. Epub 2018 Dec 21.

Service de dermatologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. Electronic address:

Background: Herein we present a case of palmoplantar keratoderma (PPK) in a young adopted girl of Chinese origin living in France.

Observation: The patient, aged six years, had presented transgressive PPK since birth, as well as erythema progressing in congestive inflammatory episodes, palmoplantar hyperhidrosis and progressive characteristics (moderate hyperkeratosis in areas of rubbing other than the palms and soles, namely the elbows and knees). Histopathological examination of a skin biopsy revealed a thick epidermis with lengthening and thickening of crests. Read More

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http://dx.doi.org/10.1016/j.annder.2018.11.005DOI Listing
February 2019
16 Reads

[Occupational characteristics and clinical manifestations of 245 cases of occupational brucellosis].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2018 Oct;36(10):755-758

HulunBuir People's Hospital, Department of Brucellosis, HulunBuir Clinical Medical College, Inner Mongolia University for Nationalitie, HulunBuir 021008, China.

To analyse epidemiological, clinical characteristics and laboratory examination results of 245 occupational brucellosis form 2008 to 2018, which providing theoretical basis for prevention and control of occupational brucellosis. Based on the China Center for Disease Control and Prevention Information System, a database of occupational brucellosis cases in HunlunBuir from January 2008 to July 2018 was established. The Epidemiological characteristics, Clinical manifestation, laboratory examination of 245 occupational brucellosis and 359 without occupational brucellosis were comparatively analyzed about the same period. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1001-9391.2018.10.009DOI Listing
October 2018
4 Reads

Lithium Treatment Is Safe in Children With Intellectual Disability.

Front Mol Neurosci 2018 22;11:425. Epub 2018 Nov 22.

Henan Key Laboratory of Child Brain Injury, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Lithium is a widely used and effective treatment for individuals with psycho-neurological disorders, and it exhibits protective and regenerative properties in multiple brain injury animal models, but the clinical experience in young children is limited due to potential toxicity. As an interim analysis, this paper reports the safety/tolerability profiles of low-dose lithium treatment in children with intellectual disability (ID) and its possible beneficial effects. In a randomized, single-center clinical trial, 124 children with ID were given either oral lithium carbonate 6 mg/kg twice per day or the same dose of calcium carbonate as a placebo ( = 62/group) for 3 months. Read More

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https://www.frontiersin.org/article/10.3389/fnmol.2018.00425
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http://dx.doi.org/10.3389/fnmol.2018.00425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262083PMC
November 2018
23 Reads

Short-Term Clinical Outcomes and Safety Associated With Percutaneous Radiofrequency Treatment for Excessive Sweating.

Aesthet Surg J 2018 Dec 9. Epub 2018 Dec 9.

Plastic surgeon in private practice in Osaka City, Japan.

Background: Primary excessive sweating of the axilla affects approximately 3.12% of the US population and has a negative impact on individuals' lives.

Objectives: We report the safety and effectiveness up to 90 days after treating excessive sweating with percutaneous radiofrequency when using a standardized protocol. Read More

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http://dx.doi.org/10.1093/asj/sjy277DOI Listing
December 2018
6 Reads

A Pocket-Friendly and Sustainable Iontophoresis Apparatus for Palmoplantar Hyperhidrosis: Advancement over a Previously Described Homemade Design.

J Cutan Aesthet Surg 2018 Jul-Sep;11(3):153-156

Department of Dermatology, People's College of Medical Sciences and Research Centre, People's University, Bhopal, Madhya Pradesh, India.

Introduction And Objectives: Tap water iontophoresis is a promising therapy for palmoplantar hyperhidrosis. Non-affordability and nonavailability of the marketed device restrict its usage for many patients hailing from villages or small cities.

Materials And Methods: In an article named "A simple user-made iontophoresis device for palmoplantar hyperhidrosis" published previously in this journal, a simple inexpensive homemade device that runs on 12 V direct current battery was described. Read More

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http://dx.doi.org/10.4103/JCAS.JCAS_58_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243828PMC
December 2018
2 Reads