2,210 results match your criteria Hyperemesis Gravidarum


Usability of Pregnancy-Unique Quantification of Emesis questionnaire in women hospitalised for hyperemesis gravidarum: a prospective cohort study.

BMJ Open 2022 May 19;12(5):e058364. Epub 2022 May 19.

Department of Obstetrics and Gynecology, University of Turku Faculty of Medicine, Turku, Finland.

Objectives: Pregnancy-Unique Quantification of Emesis (PUQE) questionnaire is mainly used in outpatient care to assess the severity of nausea and vomiting of pregnancy (NVP). Our aim was to evaluate the usability of the Finnish-translated PUQE in hospitalised women with hyperemesis gravidarum (HG).

Design: Prospective cohort study. Read More

View Article and Full-Text PDF

Changes in Serum Levels of Ketone Bodies and Human Chorionic Gonadotropin during Pregnancy in Relation to the Neonatal Body Shape: A Retrospective Analysis.

Nutrients 2022 May 9;14(9). Epub 2022 May 9.

Department of Obstetrics and Gynecology, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan.

Among the physiological changes occurring during pregnancy, the benefits of morning sickness, which is likely mediated by human chorionic gonadotropin (HCG) and induces serum ketone production, are unclear. We investigated the relationship between serum levels of ketone bodies and HCG in the first, second, and third trimesters and neonatal body shape (i.e. Read More

View Article and Full-Text PDF

Hyperemesis Gravidarum Complicated by Wernicke's Encephalopathy: A Case Report.

Cureus 2022 Apr 10;14(4):e24009. Epub 2022 Apr 10.

Department of Medicine, University of Illinois at Chicago, Chicago, USA.

Wernicke's encephalopathy (WE) is a rare neurologic disease caused by a deficiency in thiamine (B1). It is characterized by features of altered mental status, cerebellar dysfunction, and ophthalmoplegia. Most often, cases are attributed to long-term alcohol use; however, rarer causes have been described in the literature. Read More

View Article and Full-Text PDF

The Relationship between Nausea-Vomiting during Pregnancy and Attachment Styles, Marital Adjustment, and Ways of Coping.

J Sex Marital Ther 2022 May 9:1-12. Epub 2022 May 9.

Department of Midwifery, Faculty of Health Sciences, Aydın Adnan Menderes University, Aydın, Turkey.

The objective of this study is to examine the relationship between nausea and vomiting during pregnancy (NVP) and attachment styles in close relationships, marital adjustment, and ways of coping with stress. This study was performed in 2019 as an analytic case-control design. The study group consists of 60 pregnant women hospitalized with a nausea-vomiting/hyperemesis gravidarum diagnosis. Read More

View Article and Full-Text PDF

Patterns of Use and Self-reported Effectiveness of Cannabis for Hyperemesis Gravidarum.

Geburtshilfe Frauenheilkd 2022 May 6;82(5):517-527. Epub 2022 May 6.

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

There is limited research on effective treatment of Hyperemesis Gravidarum (HG), the most extreme version of nausea and vomiting during pregnancy (NVP). This paper examines current patterns of use and self-reported effectiveness of cannabis/cannabis-based products (CBP) to treat HG. The study employed a 21-question survey to gather information on demographics, antiemetic prescription use, and experience with cannabis/CBPs among individuals who experienced extreme nausea and vomiting or HG during their pregnancy. Read More

View Article and Full-Text PDF

Pneumopericardium, Epidural Pneumatosis, and Muscular Emphysema: Rare Complications of Spontaneous Pneumomediastinum Due to Refractory Hyperemesis Gravidarum.

Cureus 2022 Apr 4;14(4):e23800. Epub 2022 Apr 4.

Internal Medicine, HCA Florida North Florida Hospital, Gainesville, USA.

Various complications of hyperemesis gravidarum and pneumomediastinum have been documented in the literature. Commonly, these cases resolve spontaneously or with the use of antiemetics and supportive care. In rare instances, these symptoms persist into the second trimester and are associated with an increased risk of complications. Read More

View Article and Full-Text PDF

Ondansetron use in nausea and vomiting during pregnancy: A descriptive analysis of prescription patterns and patient characteristics in UK general practice.

Br J Clin Pharmacol 2022 Apr 28. Epub 2022 Apr 28.

PharmacoEpidemiology and Drug Safety Research Group, Department of Pharmacy, and PharmaTox Strategic Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway.

Aims: The objective of this study was to describe ondansetron drug utilization patterns during pregnancy to treat nausea and vomiting in pregnancy (NVP). Moreover, we aimed to describe the maternal factors associated with NVP and antiemetic use.

Methods: The data consist of pregnancies with a live birth(s) within an IMRD-UK registered GP practice. Read More

View Article and Full-Text PDF

Determinants of hyperemesis gravidarum among pregnant women attending health care service in public hospitals of Southern Ethiopia.

PLoS One 2022 26;17(4):e0266054. Epub 2022 Apr 26.

School of Nursing, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

Background: Hyperemesis gravidarum is severe nausea and excessive vomiting, starting between 4 and 6 gestational weeks, peak at between 8 and 12 weeks and usually improve and subside by 20 weeks of pregnancy. Identifying the determinants of hyperemesis gravidarum has a particular importance for early detection and intervention to reduce the health, psychosocial and economic impact. In Ethiopia there is low information on determinants of hyperemesis gravidarum. Read More

View Article and Full-Text PDF

Hematological Parameters to Predict the Severity of Hyperemesis Gravidarum and Ketonuria.

Rev Bras Ginecol Obstet 2022 Apr 11. Epub 2022 Apr 11.

Sakarya University, School of Medicine, Sakarya Training and Research Hospital, Department of Obstetrics and Gynecology, Sakarya, Turkey.

Objective:  Hyperemesis gravidarum (HG) is a pregnancy complication that can progress with persistent nausea and vomiting. The aim of the present study is to evaluate the relationship between hematological parameters and HG.

Method:  A total of 532 pregnant women with HG who were admitted to the Department of Obstetrics and Gynecology between March 2019 and February 2021, and 534 healthy pregnant women with characteristics similar to those of the case group were included in the study. Read More

View Article and Full-Text PDF

Long-term health outcomes of children born to mothers with hyperemesis gravidarum: a systematic review and meta-analysis.

Am J Obstet Gynecol 2022 Mar 30. Epub 2022 Mar 30.

Department of Obstetrics and Gynecology, Amsterdam Reproduction & Development, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

Objective: Hyperemesis gravidarum is characterized by severe nausea and vomiting in pregnancy, frequently resulting in severe maternal nutritional deficiency. Maternal undernutrition is associated with adverse offspring health outcomes. Whether hyperemesis gravidarum permanently affects offspring health remains unclear. Read More

View Article and Full-Text PDF

Efficacy of group biofeedback treatment on hyperemesis gravidarum with psychosomatic symptoms diagnosed with the revised version of Diagnostic Criteria for Psychosomatic Research (DCPR-R): study protocol for a randomised controlled trial.

BMJ Open 2022 03 31;12(3):e051295. Epub 2022 Mar 31.

Department of Psychology "Renzo Canestrari", University of Bologna, Bologna, Italy.

Introduction: Hyperemesis gravidarum (HG) is a condition characterised by dehydration, electrolyte imbalance, lack of nutrition and at least 5% loss in body weight, occurring in the first half of pregnancy. The aim of this trial is to examine the efficacy of group biofeedback treatment on patients with HG with psychosomatic symptoms, which will be evaluated through the revised version of Diagnostic Criteria for Psychosomatic Research (DCPR-R).

Methods And Analysis: In this single-blinded randomised controlled clinical trial, 68 patients with HG diagnosed with at least one psychosomatic syndrome according to DCPR-R and aged 18-40 years, will be recruited in a Chinese Maternal and Child Health Hospital. Read More

View Article and Full-Text PDF

Wernicke's encephalopathy secondary to hyperemesis gravidarum: A clinical challenge.

J Pak Med Assoc 2022 Mar;72(3):550-553

Department of Internal Medicine, Shifa International Hospital, Islamabad, Pakistan.

Wernicke's encephalopathy (WE) is an acute neurological condition characterized by a triad of ophthalmoplegia, ataxia and altered mental status. The underlying cause is thiamine deficiency, which may be due to multiple aetiologies. Thiamine is essential for carbohydrate and amino acid metabolism. Read More

View Article and Full-Text PDF

The effect of hyperemesis gravidarum on voice and dysphagia: a comparative study.

Authors:
Ö Koçak E Tahir

Eur Rev Med Pharmacol Sci 2022 Mar;26(5):1601-1606

Hitit University, School of Medicine Department of Obstetrics and Gynecology, Çorum, Turkey.

Objective: This study aims to determine the voice and gastrointestinal system changes of patients with hyperemesis gravidarum in the first trimester and to compare them with healthy pregnant women.

Patients And Methods: This study was conducted prospectively. Two groups were defined as hyperemesis and healthy pregnant women. Read More

View Article and Full-Text PDF

The incidence of biliary sludge in first trimester pregnancies with hyperemesis gravidarum and its effect on the course of hyperemesis gravidarum.

J Obstet Gynaecol 2022 Mar 17:1-7. Epub 2022 Mar 17.

Department of General Surgery, Gaziosmanpasa University School of Medicine, Tokat, Turkey.

Pregnancy is one of the risk factors for biliary sludge (BS) formation. In this cross-sectional study, a total of 959 pregnant women were included. Serum aspartate aminotransferase, alanine aminotransferase, sodium, potassium, triglycerides, cholesterol levels and the presence of ketones in urine were determined. Read More

View Article and Full-Text PDF

Lack of catch-up in weight gain may intermediate between pregnancies with hyperemesis gravidarum and reduced fetal growth: the Japan Environment and Children's Study.

BMC Pregnancy Childbirth 2022 Mar 12;22(1):199. Epub 2022 Mar 12.

Japan Environment and Children's Study, UOEH Subunit Center, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan.

Background: Women with nausea and vomiting of pregnancy (NVP) have higher birth weight infants, while those with hyperemesis gravidarum, a severe manifestation of NVP, have lower birth weight infants. We aimed to investigate the associations between maternal weight loss (a consequence of hyperemesis gravidarum), NVP, and infant birth weight.

Methods: This study was a secondary analysis of a nationwide birth cohort in Japan. Read More

View Article and Full-Text PDF

Pregnancy-Associated Liver Diseases.

Gastroenterology 2022 Mar 8. Epub 2022 Mar 8.

Department of Women and Children's Health, King's College London, London, UK.

The liver disorders unique to pregnancy include hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, acute fatty liver of pregnancy, and preeclampsia-associated hepatic impairment, specifically hemolysis, elevated liver enzymes, and low platelet count syndrome (HELLP). Their importance lies in the significant maternal and fetal/neonatal morbidity and mortality. Expeditious diagnosis and clinical evaluation is critical to ensure timely, appropriate care and minimize risks to the pregnant woman and her fetus/baby. Read More

View Article and Full-Text PDF

Anti-Mullerian hormone levels in spontaneous pregnancies with hyperemesis gravidarum.

J Obstet Gynaecol 2022 Mar 9:1-5. Epub 2022 Mar 9.

Obstetrics and Gynecology Department, Veris delli Ponti Hospital, Scorrano, Lecce, Italy.

We investigated the serum anti-Mullerian hormone (AMH), oestrogen and progesterone levels in spontaneously conceiving pregnant women, diagnosed for hyperemesis gravidarum (HG), in the first trimester. Pregnant women admitted at Hospital between 5 and 12 gestational weeks and treated for HG were compared, in this prospective case-control study, to a control group. The serum AMH, oestradiol, and progesterone values of both groups were evaluated and compared, and potential correlations were calculated. Read More

View Article and Full-Text PDF

A potential role for olanzapine in the treatment of hyperemesis gravidarum.

J Matern Fetal Neonatal Med 2022 Mar 3:1-4. Epub 2022 Mar 3.

PGY 1 Family Medicine, University of Calgary, Calgary, Alberta, Canada.

Hyperemesis gravidarum is a rare but potentially serious complication of pregnancy. Some women with severe symptoms and possibly psychiatric comorbidities remain symptomatic despite the use of currently available treatments. Due to its favorable safety profile, antiemetic efficacy in other conditions, and 5-HT3 antagonism, olanzapine may be a potentially useful addition to the armamentarium for management of hyperemesis gravidarum resistant to standard- of-care treatment. Read More

View Article and Full-Text PDF

Readmissions due to hyperemesis gravidarum: a nation-wide Finnish register study.

Arch Gynecol Obstet 2022 Feb 28. Epub 2022 Feb 28.

Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.

Purpose: To evaluate the burden of illness caused by hyperemesis gravidarum (HG) and association of readmissions due to HG with maternal, environmental and pregnancy-related factors, and different pregnancy outcomes.

Methods: Data of women with HG diagnosis in Finland, 2005-2017, were retrieved from health-care registers. Associations between readmissions due to HG and age, gravidity, parity, pre-pregnancy body mass index (BMI), smoking, marital status, socioeconomic status, municipality population, assisted reproductive technology (ART), and number and sex of fetuses were analyzed in pregnancies resulting in delivery. Read More

View Article and Full-Text PDF
February 2022

Whole-exome sequencing uncovers new variants in GDF15 associated with hyperemesis gravidarum.

BJOG 2022 Feb 25. Epub 2022 Feb 25.

Department of Maternal Fetal Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

View Article and Full-Text PDF
February 2022

Hyperemesis gravidarum severity, enteral tube feeding and cardiometabolic markers in offspring cord blood.

Br J Nutr 2022 Feb 24:1-30. Epub 2022 Feb 24.

Amsterdam UMC, University of Amsterdam, Department of Obstetrics and Gynaecology, Amsterdam Reproduction & Development Research Institute, Meibergdreef 9, Amsterdam, the Netherlands.

The present study aimed to investigate the association between hyperemesis gravidarum (HG) severity and the effect of early enteral tube feeding on cardiometabolic markers in offspring cord blood. We included women admitted for HG, who participated in the MOTHER randomized controlled trial (RCT) and observational cohort. The MOTHER RCT showed that early enteral tube feeding in addition to standard care did not affect symptoms or birth outcomes. Read More

View Article and Full-Text PDF
February 2022

Reversible Wernicke encephalopathy caused by hyperemesis gravidarum in the second trimester of pregnancy: a case report.

Pan Afr Med J 2021 20;40:240. Epub 2021 Dec 20.

Department of Gynecology and Obstetrics, University of Medicine of Sfax, Hedi Chaker Hospital, 3029, Sfax, Tunisia.

Wernicke encephalopathy is a potentially life-threatening neurologic syndrome caused by acute thiamine (vitamin B1) deficiency. It is usually associated with excessive alcohol consumption. Less frequently, this syndrome can be caused by persistent vomiting. Read More

View Article and Full-Text PDF
February 2022

Acoustic radiation force impulse to measure liver stiffness and predict hepatic decompensation in pregnancy with cirrhosis: A cohort study.

Arab J Gastroenterol 2022 Feb 10. Epub 2022 Feb 10.

Endemic Medicine and Hepato-gastroenterology Department, Faculty of Medicine, Cairo University, Cairo, Egypt. Electronic address:

Background And Study Aims: Pregnancy in association with cirrhosis is a rather uncommon and highly risky situation for both mother and child. We aim to study all factors and the utility of liver stiffness (LS) measurement by Acoustic Radiation Force Impulse elastography (ARFI) to predict hepatic decompensation in pregnant cirrhotic patients.

Patients And Methods: We prospectively recruited 224 pregnant women at the multidisciplinary clinic of liver disease with pregnancy, Cairo University. Read More

View Article and Full-Text PDF
February 2022

Hyperemesis gravidarum and risks of placental dysfunction disorders.

J Pak Med Assoc 2021 Dec;71(Suppl 9)(12):S24-S28

Department of Obstetrics and Gynaecology, College of Medicine, Mustansiriyah University, Iraq.

Objective: To investigate the association between hospitalisation of cases affected during the first and second trimester of pregnancy with the increased intrapartum complication attributed to placental dysfunction disorders. Additionally to highlight the distinct maternal factors and foetal morbidity patterns for improving the obstetrical outcome.

Methods: An observational study was carried out in Al-Yarmouk Hospital, Baghdad, Iraq from the 1st December 2019 to end December, 2020, recruiting 250 singleton pregnancy of gestational age >10 to >21 completed weeks until delivery. Read More

View Article and Full-Text PDF
December 2021

Wernicke's encephalopathy following hyperemesis gravidarum.

Pract Neurol 2022 Jun 4;22(3):237-238. Epub 2022 Feb 4.

Neurology, Hospital Clinic de Barcelona, Barcelona, Spain

View Article and Full-Text PDF

Emerging Progress in Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum: Challenges and Opportunities.

Front Med (Lausanne) 2021 10;8:809270. Epub 2022 Jan 10.

Institute of Nursing and Health, School of Nursing and Health, Henan University, Kaifeng, China.

Nausea and vomiting of pregnancy (NVP) is a common condition that affects up to 70% of pregnant women. Hyperemesis gravidarum (HG) is considered the serious form of NVP, which is reported in 0.3-10. Read More

View Article and Full-Text PDF
January 2022

Cerebral venous sinus thrombosis in pregnancy: A case report.

World J Clin Cases 2022 Jan;10(1):309-315

Department of Neurology, Shenzhen Longhua District Central Hospital, Shenzhen 518000, Guangdong Province, China.

Background: Cerebral venous thrombosis (CVT) is a rare but life-threatening disease in pregnant women. Anticoagulation is the first-line therapy for CVT management. However, some patients have poor outcomes despite anticoagulation. Read More

View Article and Full-Text PDF
January 2022

Thyroid Disease in Pregnancy: A Descriptive Review of Guidelines.

Obstet Gynecol Surv 2022 Jan;77(1):45-62

Assistant Professor, Third Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Importance: Thyroid disorders represent one of the most frequent complications of pregnancy associated with adverse obstetric, fetal, and neonatal outcomes, especially in case of delayed diagnosis and suboptimal management.

Objective: The aim of this study was to review and compare the recommendations of the most recently published guidelines on the diagnosis and management of these common conditions.

Evidence Acquisition: A descriptive review of guidelines from the Endocrine Society, the European Thyroid Association, the Royal Australian and New Zealand College of Obstetricians and Gynecologists, the American Thyroid Association, and the American College of Obstetricians and Gynecologists on thyroid disease in pregnancy was carried out. Read More

View Article and Full-Text PDF
January 2022

Unmasking of Gitelman Syndrome during Pregnancy in an Adolescent with Thyrotoxic Crisis.

Pediatr Rep 2021 Dec 1;13(4):632-638. Epub 2021 Dec 1.

Division of Pediatric Nephrology, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA.

Background: Gitelman syndrome (GS) is an inherited salt-losing renal tubulopathy characterized by hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria. Patients can be asymptomatic until late adolescence or adulthood, and hence may be discovered incidentally during presentation with other illnesses. GS has been described in association with thyroid disorders and should be considered in patients with hyperthyroidism and persistent hypokalemia, especially in those with associated hypomagnesemia and hypocalciuria. Read More

View Article and Full-Text PDF
December 2021

Eating habits and history of hyperemesis gravidarum as a risk factor of preeclampsia.

Gac Sanit 2021;35 Suppl 2:S501-S505

Department of Midwifery, Graduate School, Hasanuddin University, Indonesia.

Objective: This study aimed to determine the relationship between eating habits and hyperemesis gravidarum with preeclampsia incidence.

Method: This study used a cross-sectional design. The total sample was 48 pregnant women with normal and preeclamptic pregnancies who had a gestational age above 20 weeks, collecting data using a questionnaire and data analysis using the chi-square test and odds ratio (OR). Read More

View Article and Full-Text PDF
January 2022