Ann Epidemiol 2021 Mar 30;59:10-15. Epub 2021 Mar 30.
Institut national de santé publique du Québec, Montreal, QC, Canada; University of Montreal Hospital Research Centre, Montreal, QC, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, QC, Canada. Electronic address:
Purpose: We assessed whether the protective association between hyperemesis gravidarum and birth defects could be due to selection bias from exclusion of pregnancy terminations.
Methods: We designed a cohort study of 2,115,581 live births in Canada, 1990-2016. The main exposure measure was hyperemesis gravidarum. Read More