Balanced Fluid Versus Saline-Based Fluid in Post-operative Severe Traumatic Brain Injury Patients: Acid-Base and Electrolytes Assessment.
- Mohamad Hasyizan Hassan,
- Wan Mohd Nazaruddin Wan Hassan,
- Rhendra Hardy Mohd Zaini,
- Wan Fadzlina Wan Muhd Shukeri,
- Huda Zainal Abidin,
- Chong Soon Eu
Malays J Med Sci 2017 Oct 26;24(5):83-93. Epub 2017 Oct 26.
Department of Anaesthesiology and Intensive Care, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Background: Normal saline (NS) is a common fluid of choice in neurosurgery and neuro-intensive care unit (ICU), but it does not contain other electrolytes and has the potential to cause hyperchloremic metabolic acidosis with prolonged infusion. These problems may be reduced with the availability of balanced fluid (BF), which becomes a more physiological isotonic solution with the presence of complete electrolyte content. This study aimed to compare the changes in electrolytes and acid-base between NS and BF (Sterofundin® ISO) therapy for post-operative severe traumatic brain injury (TBI) patients in neuro-ICU. Read More