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J Plast Reconstr Aesthet Surg 2019 Jan 14. Epub 2019 Jan 14.

Department of Dermatology, Ho Wen Tsao Skin Clinic, No.179, Sec.2, Wenhua 3rd Rd., Linkou District, New Taipei City, Taiwan, ROC. Electronic address:

PLoS One 2019 17;14(1):e0210767. Epub 2019 Jan 17.

Department of Cardiothoracic Surgery, Aalborg University Hospital, Aalborg, Denmark.

Introduction: Carbon monoxide (CO) poisoning is frequent worldwide but knowledge regarding the epidemiology is insufficient. The aim of this study was to clarify the extent of this intoxication, its mortality and factors associated with mortality.

Materials And Methods: National databases from Statistics Denmark were used to identify individuals who suffered from CO-poisoning during 1995-2015, as well as information regarding co-morbidities, mortality and manner of death. Read More

Exp Ther Med 2019 Jan 6;17(1):465-471. Epub 2018 Nov 6.

Department of Hyperbaric Oxygen Therapy, Affiliated Hongqi Hospital, Mudanjiang Medical University, Mudanjiang, Heilongjiang 157011, P.R. China.

The present study aimed to investigate the therapeutic effect of combined hyperbaric oxygen and radiation therapy for the treatment of single brain metastasis (SBM), as well as its influence on osteopontin (OPN) and matrix metalloproteinase-9 (MMP-9). A total of 86 patients with SBM were admitted to Hongqi Hospital from January 2013 to January 2016 and those included within the study were randomly divided into two groups. The control group was only treated with whole brain radiotherapy, while the observation group was treated with hyperbaric oxygenation combined with whole brain radiotherapy. Read More

Spinal Cord 2019 Jan 14. Epub 2019 Jan 14.

Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.

Study Design: Animal study.

Objectives: To evaluate the efficacy of hyperbaric oxygen (HBO) therapy for spinal cord injury (SCI) in rats with different treatment course using diffusion tensor imaging (DTI).

Setting: Hospital in Fuzhou, China. Read More

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Nov;43(11):1251-1256

Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Calcific uremic arteriopathy (CUA), termed calciphylaxis, is a rare but highly fatal clinical syndrome. There is no clearly laboratory diagnostic criteria for CUA. The medium and small arterial calcification and microthrombosis discovered by skin biopsy, radiologic imaging，bone scan and the evidence of activation of the bone morphogenetic protein signal (BMPs) transduction pathway are useful for early diagnosis of this disease. Read More

Cochrane Database Syst Rev 2019 Jan 14;1:CD012732. Epub 2019 Jan 14.

Department of Rehabilitation Medicine, Royal Melbourne Hospital, Royal Park Campus, Poplar Road, Parkville, Melbourne, Victoria, Australia, 3052.

Background: Multiple sclerosis (MS) is a major cause of chronic, neurological disability, with a significant long-term disability burden, often requiring comprehensive rehabilitation.

Objectives: To systematically evaluate evidence from published Cochrane Reviews of clinical trials to summarise the evidence regarding the effectiveness and safety of rehabilitation interventions for people with MS (pwMS), to improve patient outcomes, and to highlight current gaps in knowledge.

Methods: We searched the Cochrane Database of Systematic Reviews up to December 2017, to identify Cochrane Reviews that assessed the effectiveness of organised rehabilitation interventions for pwMS. Read More

Oral Dis 2019 Jan 11. Epub 2019 Jan 11.

Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea.

Objective: To determine the synergistic effect of parathyroid hormone (PTH) [1-34] in combination with hyperbaric oxygen (HBO) on bone graft in a rat calvarial bone defect model under impaired osteogenic conditions.

Materials And Methods: Twenty-four rats were divided into 3 groups. Localized radiation with a single 12 Gy dose was administered to the calvaria. Read More

Cancer 2019 Jan 11. Epub 2019 Jan 11.

Survivorship Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.

Background: Existing research suggests that progressive resistance training (PRT) after breast cancer (BC) surgery is safe, but the preventive effect on arm lymphedema has yet to be determined.

Methods: Women aged 18 to 75 years who were undergoing BC surgery with axillary lymph node dissection were eligible for the study. Recruited on the day of surgery, participants were allocated to intervention or usual care by computer randomization. Read More

World J Clin Oncol 2019 Jan;10(1):1-13

University at Buffalo, The State University of New York, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY 14214, United States.

Xerostomia, or dry mouth, is a significant problem affecting quality of life in patients treated with radiation therapy for head and neck cancer. Strategies for reduction of xerostomia burden vary widely, with options including: sialagogue medications, saliva substitutes, acupuncture, vitamins, hyperbaric oxygen, submandibular gland transfer, and acupuncture or associated treatments. In this review, we sought to evaluate long-term outcomes of patients treated with various interventions for radiation-induced xerostomia. Read More

Emerg Med Int 2018 4;2018:2159147. Epub 2018 Dec 4.

Acute and General Medicine, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan.

Background: The aim of this study was to identify practice differences in the treatment of carbon monoxide (CO) poisoning with or without hyperbaric oxygen (HBO) therapy in Japan.

Materials And Methods: Using an online survey website (Google form), we created a questionnaire and invited interested institutions to join the COP-J Study, a prospective observational study of CO poisoning in Japan.

Results: Forty-eight (63%) of 76 institutions replied to the questionnaire. Read More

J Thorac Dis 2018 Nov;10(11):6176-6183

Department of Surgery II, Faculty of Medicine, Yamagata University, Iida-Nishi, Yamagata City, Yamagata Prefecture, Japan.

Background: Hyperbaric oxygen therapy (HBOT) has been used successfully in the treatment of specific ischemic injuries, but has been a little evaluated specifically in postoperative ischemic bronchitis (POIB). The purpose of this study was to evaluate the effect of HBOT when used for POIB after resection of lung cancer.

Methods: From January 1999 to December 2016, 1,100 patients underwent lymph node dissection (LND) and either anatomic pulmonary resection or lung resection with bronchoplasty for lung cancer. Read More

Front Psychol 2018 17;9:2495. Epub 2018 Dec 17.

Sagol Center for Hyperbaric Medicine and Research, Assaf Harofeh Medical Center, Zerifin, Israel.

Fibromyalgia syndrome (FMS), a condition considered to represent a prototype of central sensitization syndrome, can be induced by different triggers including childhood sexual abuse (CSA). Recent studies have demonstrated hyperbaric oxygen therapy (HBOT) can induce neuroplasticity and improve clinical outcome of FMS. The aim of the current study was to evaluate the effect of HBOT on patients suffering from FMS with a history of CSA. Read More

High Alt Med Biol 2019 Jan 7. Epub 2019 Jan 7.

1 IFREMMONT (Institut de Formation et de Recherche en Médecine de Montagne) Hôpital de Chamonix, Hôpital de Chamonix, Chamonix, France.

Savina, Yann, Sandra Leal, Pascal Zellner, François Becker, Monica Piris, and Emmanuel Cauchy. The effect of a 300 mbar increase in barometric pressure on digital microcirculation in healthy subjects exposed to high altitude: Is the use of a portable hyperbaric chamber to treat frostbite and/or hypothermia in the field indicated? (Flow_Pulse Study). High Alt Med Biol. Read More

Cancer Manag Res 2019 21;11:167-177. Epub 2018 Dec 21.

Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China,

Radiotherapy (RT) is a major treatment for malignant tumors. The latest data show that >70% of patients with malignant tumors need RT at different periods. Skin changes can be experienced by up to 95% of patients who underwent RT. Read More

J R Army Med Corps 2019 Jan 5. Epub 2019 Jan 5.

Department of Otorhinolaryngology, Central Military Hospital, Ministry of Defense, Utrecht, The Netherlands.

Introduction: Acute acoustic trauma (AAT) is a sensorineural hearing impairment due to exposure to an intense impulse noise which causes cochlear hypoxia. Hyperbaric oxygen therapy (HBO) could provide an adequate oxygen supply. The aim was to investigate the effectiveness of early treatment with combined HBO and corticosteroid therapy in patients with AAT compared with corticosteroid monotherapy. Read More

Physiol Res 2018 Dec;67(Supplementum 4):S633-S643

Institute of Physiology, Faculty of Medicine in Plzeň, Charles University, Plzeň, Czech Republic.

Hyperbaric oxygen (HBO) therapy, i.e. breathing pure oxygen under increased environmental pressures serves as a treatment for diverse medical conditions. Read More

Dermatology 2019 Jan 3:1-10. Epub 2019 Jan 3.

Department of Nephrology and Organ Transplantation, Center for Rare Renal Disease, University Hospital of Toulouse, Toulouse,

Background: Calciphylaxis (CPX) is a rare and life-threatening disease characterized by vascular calcification and development of painful and necrotizing skin lesions with a challenging management. Mechanisms of CPX are complex and include an imbalance between vascular calcification promoters and inhibitors, and frequently vitamin K deficiency.

Objectives: To describe the various presentations and identify predictive factors of death in patients with CPX. Read More

Physiol Rep 2019 Jan;7(1):e13961

Department of Molecular Pharmacology and Physiology, Laboratory of Metabolic Medicine, University of South Florida, Tampa, Florida.

Central nervous system oxygen toxicity (CNS-OT) manifests as tonic-clonic seizures and is a limitation of hyperbaric oxygen therapy (HBOT), as well as of recreational and technical diving associated with elevated partial pressure of oxygen. A previous study showed that ketone ester (1,3-butanediol acetoacetate diester, KE) administration delayed latency to seizures (LS) in 3-month-old Sprague-Dawley (SD) rats. This study explores the effect of exogenous ketone supplements in additional dosages and formulations on CNS-OT seizures in 18 months old SD rats, an age group correlating to human middle age. Read More

Ann Surg Treat Res 2019 Jan 26;96(1):34-40. Epub 2018 Dec 26.

Department of Histology and Embryology, Recep Tayyip Erdogan University, Faculty of Medicine, Rize, Turkey.

Purpose: To research the effects of iloprost (IL) and hyperbaric oxygen (HBO) combination treatment on lung injury and on tumor necrosis factor alpha (TNF-α), myeloperoxidase (MPO), malondialdehyde (MDA), and soluble intercellular adhesion molecule-1 (sICAM-1) levels after tissue or organ ischemia-reperfusion, and on ischemia-reperfusion induced lung neutrophil sequestration.

Methods: Forty white New Zealand rabbits were assigned randomly into 5 groups: HBO, IL, HBO+IL, control, and sham groups. TNF-α values were checked before ischemia, in the 1st hour of ischemia and in the 1st and 4th hours of reperfusion, also at the end of reperfusion period, plasma and tissue MPO values, MDA values, and sICAM-1 levels were detected. Read More

Z Evid Fortbild Qual Gesundhwes 2018 Dec 28. Epub 2018 Dec 28.

Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Hannover, Deutschland. Electronic address:

Background: Carbon monoxide poisoning (COP) is the most common cause for poisoning by inhalation in Germany. In the past 8 years, a marked increase in the number of COP-related deaths has been registered nationwide. A national German guideline is missing. Read More

J Cancer Res Ther 2018 ;14(7):1650-1654

Department of Neurosurgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China.

Purpose: The objective of the study is to explore the etiology, clinical manifestations, imaging features, diagnosis, treatment, and prognosis of cerebral air embolism complicated computed tomography (CT) scan-guided percutaneous liver biopsy.

Materials And Methods: A case of air embolism was developed in the brain during a CT-guided percutaneous needle biopsy of the liver. In addition, retrospective analysis was performed on the previously reported typical cases of cerebral air embolism secondary to CT-guided percutaneous lung biopsy. Read More

Biol Pharm Bull 2018 Dec 27. Epub 2018 Dec 27.

Department of dermatological, Jinshan Hospital Affiliated to Fudan University.

The photodynamic therapy (PDT) depends on the presence of molecular oxygen. Thus, the efficiency of PDT is limited in anoxic regions of tumor tissue and vascular shutdown. It is reported the use of hyperbaric oxygen (HBO) may enhance the efficiency of PDT. Read More

Clin Exp Emerg Med 2018 Dec 31;5(4):278-281. Epub 2018 Dec 31.

Department of Ophthalmology, Yonsei University Wonju College of Medicine, Wonju, Korea.

Central retinal artery occlusion (CRAO) is considered an ophthalmologic emergency. The prognosis of this disease is very poor. Currently, there is no generally effective therapy available to treat CRAO. Read More

Sao Paulo Med J 2018 Sep-Oct;136(5):421-432

MD. Associate Professor, Department of Intensive Care Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Background: This study aimed to compare the effects on mortality of albumin and crystalloid, used for fluid resuscitation among adult patients with septic shock, through conducting a meta-analysis and trial sequential analysis (TSA).

Design And Setting: Meta-analysis and TSA conducted at Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Methods: Data were collected from several major databases including MEDLINE, EMBASE, Clinical Trials. Read More

Med Chem 2018 Dec 18. Epub 2018 Dec 18.

Department of Respiratory Medicine, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 530021. China.

Hyperbaric Oxygenation Therapy (HBOT) is used as adjunctive method for multiple diseases. The method meets the routine treating and is non-invasive, as well as provides 100% pure oxygen (O2) which is at above-normal atmospheric pressure in a specialized chamber. It is well known that in the condition of O2 deficiency, it will induce a series of adverse events. Read More

BMC Nephrol 2018 Dec 19;19(1):370. Epub 2018 Dec 19.

Division of Nephrology, Department of medicine, the First Affiliated Hospital, Jinan University, Guangzhou, 510630, Guangdong, China.

Background: Uremic encephalopathy (UE), a toxic metabolic encephalopathy, is an uncommon complication resulting from endogenous uremic toxins in patients with severe renal failure. UE syndrome can range from mild inattention to coma. The imaging findings of UE include cortical or subcortical involvement, basal ganglia involvement and white matter involvement. Read More

Arthroplast Today 2018 Dec 1;4(4):510-515. Epub 2018 Sep 1.

TEAMHealth Anesthesia Research Institute, Tampa, FL, USA.

Background: Osteonecrosis of the knee (ONK) is a form of aseptic necrosis resulting from ischemia to subchondral bone tissue. Typically, treatment is invasive. Hyperbaric oxygen therapy (HBOT) may provide a noninvasive alternative by improving oxygenation and reperfusion of ischemic areas. Read More

J Clin Med 2018 Dec 14;7(12). Epub 2018 Dec 14.

Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.

Background: This study tested the hypothesis that hyperbaric oxygen (HBO) therapy enhanced the circulating levels of endothelial progenitor cells (EPCs), soluble angiogenesis factors, and blood flow in ischemic areas in patients with peripheral arterial occlusive disease (PAOD).

Methods: In total, 57 consecutive patients with PAOD undergoing the HBO therapy (3 atmospheres (atm) for 2 h each time) were prospectively enrolled into the present study. Venous blood sampling was performed to assess the circulating levels of EPCs and soluble angiogenesis factors prior to and during five sessions of HBO therapy. Read More

Eur Rev Med Pharmacol Sci 2018 Dec;22(23):8480-8486

Ospedale Civile Urbino - SSD Oncologia Ginecologica, Urbino, Italy.

Objective: This is a pilot study to evaluate the effectiveness of concomitant administration of hyaluronic acid and topical hyperbaric oxygen therapy (THOT) by a specifically designed medical device (vaginal natural oxygenation device, VNOD) in improving the symptomatology of postmenopausal patients with vulvo-vaginal atrophy (VVA).

Patients And Methods: Women with diagnosis of severe VVA from September 2017 to May 2018 were included. Five biweekly administration of THOT and concomitant of hyaluronic acid were performed with a specifically designed medical device. Read More

Hinyokika Kiyo 2018 10;64(10):415-418

Hakodate Goryokaku Hospital.

A 60-year-old man presented at our hospital with gross hematuria. He had been treated for nephrotic syndrome with cyclophosphamide and steroids since he was in his 20s. We detected diffuse hemorrhagic cystitis on cystoscopy and diagnosed him with cyclophosphamide-induced hemorrhagic cystitis. Read More

Exp Ther Med 2018 Dec 26;16(6):4918. Epub 2018 Sep 26.

[This corrects the article DOI: 10.3892/etm.2018. Read More

Int J Gen Med 2018 20;11:431-442. Epub 2018 Nov 20.

Department of Internal Medicine, Graduate Medical Education, St Vincent Charity Medical Center, Cleveland, OH, USA,

Hypoxia causes a cascade of activity from the level of the individual down to the regulation and function of the cell nucleus. Prolonged periods of low oxygen tension are a core feature of several disease states. Advances in the study of molecular biology have begun to bridge the gap between the cellular response to hypoxia and physiology. Read More

Plast Reconstr Surg Glob Open 2018 Oct 2;6(10):e1927. Epub 2018 Oct 2.

Section of Plastic Surgery, Department of Surgery, University of Calgary, Calgary, Alberta.

Mucormycosis is a rare fungal infection caused by ubiquitous fungi in the order Mucorales. It is the most rapidly progressing fulminant fungal infection that mimics necrotizing soft-tissue infections. Overwhelming fungal sepsis develops quickly and mortality rates approach 70%. Read More

Turk J Emerg Med 2018 Dec 13;18(4):176-178. Epub 2018 Apr 13.

Marmara University Pendik Education and Research Hospital, Department of Emergency Medicine, Istanbul, Turkey.

Methemoglobinemia is a rare but clinically important condition that should be considered among differential diagnosis' in cyanosis. The conventional treatments of methemoglobinemia are high flow oxygen and methylene blue therapies. We present a 52-year-old male patient who admitted to emergency room with severe cyanosis and dyspnea after he was exposed to paint thinner and zinc phosphate solution. Read More

Diving Hyperb Med 2018 Dec;48(4):259-261

Department of Pulmonary Medicine, Kameda Medical Centre, Kamogawa, Chiba, Japan.

Immersion pulmonary oedema (IPE) is particularly associated with an excessive reaction to exercise and/or cold stress. IPE usually resolves without recompression therapy within a day or two. Herein we report a diver diagnosed with IPE, in whom symptoms persisted for five days. Read More

Diving Hyperb Med 2018 Dec;48(4):229-234

Department of Diving and Hyperbaric Medicine, Prince of Wales Hospital, Sydney, Australia.

Background: Nutritional assessment and support is essential for wound management. The hyperbaric oxygen clinic is a unique outpatient service where chronically unwell patients present daily for hyperbaric oxygen treatment (HBOT) over several weeks, allowing time for effective nutritional intervention. This is the first study to examine the prevalence of those at risk of malnutrition in a cohort of hyperbaric medical patients. Read More

Diving Hyperb Med 2018 Dec;48(4):209-217

Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Canada.

Introduction: High concentration normobaric oxygen (O₂) is a priority in treating divers with suspected decompression illness. The effect of different O₂ mask configurations on tissue oxygenation when breathing with a demand valve was evaluated.

Methods: Sixteen divers had tissue oxygen partial pressure (PtcO₂) measured at six limb sites. Read More

Diving Hyperb Med 2018 Dec;48(4):206-207

Nutrition Department, Alfred Health, Melbourne.

Outpatients who receive hyperbaric oxygen treatment (HBOT) may represent a group at significant risk of malnutrition owing to the underlying conditions that are often treated with HBOT (e.g., non-healing diabetic wounds and radiation-induced skin injury). Read More

Biomed Res Int 2018 1;2018:4608150. Epub 2018 Nov 1.

Department of Emergency Medicine, Chi Mei Medical Center, Tainan, Taiwan.

High-mountain sickness is characterized by brain and pulmonary edema and cognitive deficits. The definition can be fulfilled by a rat model of high-altitude exposure (HAE) used in the present study. This study aimed to investigate the protective effect of hyperbaric oxygen therapy (HBOT) and to determine the underlying mechanisms. Read More

J Arthroplasty 2019 Feb 11;34(2):338-345.e1. Epub 2018 Oct 11.

Department of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, Chongqing, Republic of China.

Background: Common three-dimensional (3D)-printed anatomic templates have generally been used to reconstruct the pelvis after zone II and III borderline pelvic tumor resection. However, gradual increases in postoperative implant complications and the tumor recurrence rate have been observed. This study aimed to introduce the innovative application of a modified 3D-printed anatomic template with a customized cutting block for pelvic reconstruction and to comparatively analyze the common and modified 3D-printed anatomic templates. Read More

Ann Vasc Surg 2018 Nov 26. Epub 2018 Nov 26.

Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, UK.

Background: Diabetes mellitus is one of the most common chronic diseases worldwide. Diabetic foot ulcers (DFUs) occur in over 10% of diabetic patients and are associated with high morbidity. Clinical trials have shown benefit from extracorporeal shockwave therapy (ESWT) in a DFU healing. Read More

Aerosp Med Hum Perform 2018 Dec;89(12):1085-1088

Decompression sickness is a condition that results from an abrupt change from a higher to a lower pressure. It is described most commonly in divers; however, it can occur in aviation incidents, which this case report will discuss. Following an acute cabin depressurization incident, 36 patients presented to a small outpatient clinic with multiple symptoms, including fatigue, headache, nausea, vomiting, and dizziness. Read More

J Neurol Sci 2019 Jan 22;396:187-192. Epub 2018 Nov 22.

Institute of Environmental and Occupational Health Sciences, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Clinical Toxicology & Occupational Medicine, Department of Medicine, Veterans General Hospital, Taipei, Taiwan. Electronic address:

Objectives: Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide poisoning; neuropsychiatric disorders can occur within a few days of recovery from acute poisoning. Hyperbaric oxygen therapy (HBOT) has been the main treatment of carbon monoxide (CO) poisoning and was recommended as the treatment choice for CO poisoning by the American Undersea and Hyperbaric Medical Society and the Tenth European Consensus Conference on Hyperbaric Medicine of the European Underwater and Baromedical Society. However, the optimal timing for commencing HBOT in patients with CO poisoning remains unknown. Read More

Biochemistry (Mosc) 2018 Oct;83(10):1245-1254

Southern Federal University, Academy of Biology and Biotechnology, Department of Biochemistry and Microbiology, Rostov-on-Don, 344090, Russia.

Here, we studied the effect of the mitochondria-targeted antioxidant SkQ1 (plastoquinone cationic derivative) on the CASP3 gene expression and caspase-3 activity in rat cerebral cortex and brain mitochondria under normal conditions and in oxidative stress induced by hyperbaric oxygenation (HBO). Under physiological conditions, SkQ1 administration (50 nmol/kg, 5 days) did not affect the CASP3 gene expression and caspase-3-like activity in the cortical cells, as well as caspase-3-like activity in brain mitochondria, but caused a moderate decrease in the content of primary products of lipid peroxidation (LPO) and an increase in the reduced glutathione (GSH) level. HBO-induced oxidative stress (0. Read More

Rozhl Chir 2018 ;97(9):432-441

Necrotizing fasciitis is a dangerous bacterial infectious disease that is not commonplace in Czech society. On the other hand, neither is it so rare that the majority of surgeons should not come across it occasionally. In the early stages, pathological changes in fascia, subcutaneous tissue and even skin may run an inconspicuous course. Read More

Scand J Trauma Resusc Emerg Med 2018 Nov 22;26(1):103. Epub 2018 Nov 22.

Department of Cardiothoracic Surgery, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.

Background: Severe intoxication with carbon monoxide (CO) is extremely lethal and causes numerous deaths due to cardiac or respiratory failure. Conventional intensive treatment may not be sufficient. The aim of this study was to investigate the treatment effect of extracorporeal veno-arterial extracorporeal membrane oxygenation (ECMO) following severe CO poisoning in an experimental porcine model. Read More

Asian J Neurosurg 2018 Oct-Dec;13(4):959-970

Department of Neurology, University of New Mexico, Albuquerque, NM, USA.

Skull base osteomyelitis (SBO) is a complex and fatal clinical entity that is often misdiagnosed for malignancy. SBO is commonly a direct complication of otogenic, sinogenic, odontogenic, and rhinogenic infections and can present as central, atypical, or pediatric clival SBO. This review describes the clinical profile, investigational approach, and management techniques for these variants. Read More

Contemp Oncol (Pozn) 2018 30;22(3):202-204. Epub 2018 Sep 30.

Department of Otorhinolaryngology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey.

One of the standard treatments in laryngeal cancer is radiotherapy (RT). Many short- and long-term complications can occur in the region that has received radiotherapy. Definitive treatment of the emerging complications is still debatable, and treatment is challenging for radiation oncologists and ear nose throat specialists. Read More

Clin J Oncol Nurs 2018 Dec;22(6):E146-E151

Scripps MD Anderson Cancer Center, Sanford Burnham Presbys Medical Discovery Institute, and Scripps Research Translational Institute.

Background: Hyperbaric oxygen therapy is a rare treatment modality for hemorrhagic cystitis (HC) following BK virus reactivation in the immunosuppressed population. Clinicians need to be aware of the etiology, preventive measures, complications, and various management techniques in HC while treating patients undergoing bone marrow transplantation.

Objectives: This study details the pathologic progression of HC in a patient with acute lymphoblastic leukemia harboring BK virus after cytotoxic induction chemotherapy and haploidentical marrow transplantation. Read More

Plast Surg (Oakv) 2018 Nov 18;26(4):250-255. Epub 2018 Jan 18.

Department of Plastic Surgery, Assaf Harofeh Medical Center, Tzrifin, Israel.

Background: Phenol chemical peeling (PCP) treatment is associated with prolonged recovery and sustained adverse events. Hyperbaric oxygen therapy (HBOT) is known to accelerate wound healing. The purpose of the current study was to evaluate the effect of HBOT on PCP recovery period and adverse events. Read More