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Sci Rep 2020 Jul 10;10(1):11477. Epub 2020 Jul 10.

Department of Gastroenterological Endoscopy, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan road, Xigang district, Dalian, 116011, Liaoning, China.

In order to evaluate the effectiveness of various methods we applied to decrease the influence of periampullary diverticula (PAD) on the success rate and complications of endoscopic retrograde cholangiopancreatography (ERCP) in the treatment of common bile duct (CBD) stones, we enrolled patients with CBD stones who had been treated by ERCP in our hospital between January 2015 and December 2018. According to the presence of PAD, the patients were divided into a PAD group and a non-PAD group. The rate of complete stone removal in the first session, the rate of overall stone removal, the frequency of application of mechanical lithotripsy, and procedure-related complications, including bleeding, hyperamylasemia, pancreatitis, perforation, and infection of biliary tract were recorded. Read More

Surgery 2020 Jul 5. Epub 2020 Jul 5.

Department of General and Pancreatic Surgery - The Pancreas Institute, University of Verona Hospital Trust, Italy. Electronic address:

Background: Postoperative hyperamylasemia is a frequent finding after pancreatoduodenectomy, but its incidence and clinical implications have not yet been analyzed systematically. The aim of this review is to reappraise the concept of postoperative hyperamylasemia with postoperative acute pancreatitis, including its definition, interpretation, and correlation.

Methods: Online databases were used to search all available relevant literature published through June 2019. Read More

Gastrointest Endosc 2020 Jun 29. Epub 2020 Jun 29.

Senior Professor, Department of Gastroenterology, SMS Medical College and Hospitals, Jaipur, India. Electronic address:

Background And Aims: Precut sphincterotomy, usually performed after prolonged and failed cannulation, is considered as one of the risk factors for post-ERCP pancreatitis (PEP). There are limited studies on primary needle-knife precut for the prevention of PEP. The aim of the study was to assess the safety and efficacy of primary precut. Read More

J Orthop Sci 2020 Jun 25. Epub 2020 Jun 25.

Department of Orthopaedic Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa prefecture, 216-8511, Japan.

Background: Despite the identification of various risk factors for pancreatitis and hyperamylasemia following spinal surgery, no report has investigated the relationship between spinal alignment changes and elevated serum amylase levels. The purpose of this study was to investigate the relationship between spinal alignment changes and hyperamylasemia after spinal fusion.

Methods: A total of 222 patients whose serum pancreatic amylase levels were measured before and after spinal surgery from December 2017 to May 2019 were included. Read More

Cureus 2020 May 21;12(5):e8217. Epub 2020 May 21.

Regional Transplant Unit, Belfast Health and Social Care Trust, Belfast, GBR.

Introduction The aetiology of pain after laparoscopic donor nephrectomy remains unclear. Given the proximity of the left kidney to the tail of the pancreas, we aimed to assess whether mobilisation and retrieval of the left kidney might inflame the pancreas, leading to pain and hyperamylasaemia in the post-operative period. Patient and methods In the present study, 16 consecutive live kidney donors were analysed in the same three months period. Read More

Turk J Pharm Sci 2020 Feb 19;17(1):68-73. Epub 2020 Feb 19.

Gaziantep University, School of Medicine, Department of Endocrinology and Metabolism, Gaziantep, Turkey.

Objectives: In different studies, it has been shown that the use of dipeptidyl peptidase-4 (DPP-4) inhibitors (DPP-4 inh) does not increase the risk of pancreatitis or pancreatic cancer. Although the number of studies involving clinical pancreatitis clinics is sufficient, the number of studies involving clinical non-pancreatitis hyperamylasemia is rare. The aim of the study was to investigate the relationship between DPP-4 inh usage and amylase and lipase increment without clinical pancreatitis symptoms. Read More

J Int Med Res 2020 Mar;48(3):300060520910037

Department of Emergency Medicine, the 5th Medical Center of Chinese PLA General Hospital, Beijing, China.

Surg Endosc 2020 Mar 5. Epub 2020 Mar 5.

Department of Gastrointestinal Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, People's Republic of China.

Background And Aims: Previous studies have suggested that aggressive hydration with lactated ringer solution are one of the protective factors in preventing post endoscopic retrograde cholangiopancreatography (post-ERCP). We conducted a systematic review and meta-analysis to examine the efficacy aggressive hydration with lactated Ringer solution in preventing PEP.

Methods: All published and unpublished articles on aggressive hydration with lactated ringer solution in those underwent ERCP procedure for any reasons were screened for eligibility. Read More

Rev Col Bras Cir 2020 31;46(6):e20192285. Epub 2020 Jan 31.

Universidade do Extremo Sul Catarinense (UNESC), Curso de Medicina, Criciúma, SC, Brasil.

Objective: to establish a correlation between objective data collected at the initial evaluation and the outcomes in cases of acute abdominal pain.

Methods: we conducted a retrospective, case-control study in which we reviewed medical records of patients treated at an emergency room in 2016, diagnosed with abdominal and pelvic pain.

Results: of the 2,352 medical records evaluated, we considered 330 valid for the study. Read More

Can Vet J 2020 02;61(2):147-152

Pathology and Microbiology (Foote, Gilroy, Burton, Horney, Lopez) and Companion Animal Departments (Savidge), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3; Cornwall Veterinary Clinic, 375 Trans-Canada Highway, Cornwall, Prince Edward Island C0A 1H0 (Goff ).

Two cases of canine zinc toxicosis with pancreatic disease are reported. Both dogs had pigmenturia, pallor, regenerative anemia, an inflammatory leukogram, hyperbilirubinemia, hyperamylasemia, and hyperlipasemia. Zinc toxicosis was diagnosed post-mortem in patient 1 based on the discovery of a metallic gastric foreign object, pancreatic necrosis, nephrosis, and high tissue zinc concentrations. Read More

Medicine (Baltimore) 2020 Jan;99(3):e18861

Department of Internal Medicine, College of Medicine, the Catholic University of Korea, Seoul, Korea.

Serum amylase levels in patients with acute pancreatitis often remain or fluctuate above the upper normal limit for over a week. This study investigated the clinical characteristics of patients with prolonged hyperamylasemia and their prognoses, including recurrence.We retrospectively analyzed patients with first attacks of acute pancreatitis in a single center between March 2010 and December 2016. Read More

J Clin Gastroenterol 2020 Apr;54(4):305-313

Department of Gastroenterology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an.

Background: Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most common complication of ERCP procedure. Nonsteroidal anti-inflammatory drugs (NSAIDs) are reported to be one protective pharmacological agent with great efficacy regarding this complication. Recently, more trails have addressed this issue and some inconsistent results appeared. Read More

Surg Case Rep 2020 Jan 9;6(1):11. Epub 2020 Jan 9.

Department of General Surgery, Asamananroku Komoro Medical Center, 3-3-21 Aioicho, Komoro, Nagano, 384-8588, Japan.

Background: Hiatal hernia is defined by the permanent or intermittent prolapse of any abdominal structure into the chest through the diaphragmatic esophageal hiatus. Prolapse of the stomach, intestine, transverse colon, and spleen is relatively common, but herniation of the pancreas is a rare condition. We describe a case of acute pancreatitis and bile duct dilatation secondary to a massive hiatal hernia of pancreatic body and tail. Read More

Clin J Gastroenterol 2020 Jan 8. Epub 2020 Jan 8.

Department of Hematology, Toranomon Hospital, Tokyo, Japan.

We report a case of simultaneous macroamylasemia and macrolipasemia complicated with mucosa-associated lymphoid tissue (MALT) lymphoma. A 78-year-old man presented with hyperamylasemia and hyperlipasemia for 2 years and was misdiagnosed with chronic pancreatitis at another hospital. However, his other pancreatic enzymes were normal, his amylase-creatinine clearance ratio was low, and no definite findings of pancreatic disease were evident. Read More

Ann Pharmacother 2020 Jul 5;54(7):720-721. Epub 2020 Jan 5.

Medicine (Baltimore) 2020 Jan;99(1):e18536

Department of Gastroenterology.

It remains challenging for endoscopists to manage pancreaticobiliary diseases in patients with ectopic papilla of Vater by endoscopic retrograde cholangiopancreatography (ERCP). The present study sought to evaluate the efficacy and safety of ERCP for this issue.Consecutive patients with ectopic papilla of Vater who underwent initial ERCP due to pancreaticobiliary diseases were retrospectively analyzed. Read More

J Hepatobiliary Pancreat Sci 2019 Dec 16;26(12):541-547. Epub 2019 Nov 16.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Omori Medical Center, Tokyo, Japan.

Background: In pancreaticobiliary maljunction (PBM), reflux of pancreatic juice and bile produces various pathological conditions in the biliary tract and pancreas. Clinical features according to the classification of PBM by confluence between the distal bile duct and the main pancreatic duct proposed in 2015 were evaluated in children.

Methods: Clinical features and complicating diseases according to the PBM classification were evaluated in 168 adult PBM patients. Read More

Pancreatology 2019 Sep 30;19(6):819-827. Epub 2019 Jul 30.

Division of Gastroenterology, Department of Internal Medicine, East Tennessee State University, Johnson City, TN, USA.

Background: Periprocedural intravenous hydration is suggested to decrease the risk of post-ERCP pancreatitis (PEP). However, quality of evidence supporting this suggestion remains poor. Here we hypothesized that aggressive hydration(AH) could be an effective preventive measure. Read More

Middle East J Dig Dis 2019 Apr 10;11(2):76-83. Epub 2019 Feb 10.

Department of Critical Care Nursing, Center for Nursing Care Research, Nursing and Midwifery Faculty, Iran University of Medical Sciences, Tehran, Iran.

BACKGROUND Pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ERCP), which may lead to death. The purpose of this study was to evaluate the preventive effect of aggressive fluid therapy on the incidence of post-ERCP pancreatitis. METHODS In double-blind controlled condition, 240 patients were selected and divided into two groups. Read More

Clin Nucl Med 2019 Sep;44(9):e522-e523

From the Radiology Institute.

MR and F-FDG PET/MR images of a 15-year-old boy with recurrent mild abdominal pain and hyperamylasemia demonstrating a pancreatic head lesion hypointense on the T1-weighted and slightly hyperintense on the T2-weighted images, with very small pseudocystic areas, restricted diffusion on the apparent diffusion coefficient map, and focal FDG uptake. No other pathologic findings such as enlarged lymph nodes, vascular invasion, metastases, dilatation of the main pancreatic duct, or pathologic uptake of the parotid glands were detected. The MR features, even if atypical, together with the focal uptake, allowed the diagnosis of pediatric solid pseudopapillary pancreatic tumor, which was then confirmed by histology. Read More

Zhonghua Wai Ke Za Zhi 2019 Jul;57(7):534-539

Department of Hepato-Biliary-Pancreatic Surgery, Changhai Hospital, Navy Medical University, Shanghai 200433, China.

To investigate the prognostic factors of hyperamylasemia following pancreaticoduodenectomy (PD) . Clinical data of 359 patients were collected prospectively who underwent PD by the same group at Changhai Hospital of Navy Medical University from January 2017 to June 2018.There were 212 males and 147 females. Read More

Ann Pharmacother 2019 10 20;53(10):1067-1068. Epub 2019 May 20.

Asian J Endosc Surg 2020 Apr 9;13(2):195-199. Epub 2019 May 9.

Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Introduction: Our aim was to introduce a simple way of making a self-releasing biliary stent for laparoscopic common biliary duct exploration.

Methods: To make a self-releasing biliary stent, an absorbable thread was sutured to a J-shape polyurethane biliary stent. After the evacuation of the calculi, a guide wire was placed into the duodenum antegradely, facilitating the insertion of the biliary stent. Read More

Abdom Radiol (NY) 2019 07;44(7):2494-2500

Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: Elucidating the association between pancreatic ductal anomalies and chronic asymptomatic pancreatic hyperenzymemia using magnetic resonance cholangiopancreatography.

Methods: We conducted a single-center, retrospective, case-control study. The healthy community group comprised 554 subjects who participated in a paid, whole-body health checkup program. Read More

J Coll Physicians Surg Pak 2019 Apr;29(4):400

Department of General Surgery, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong, 518118, China.

Surg Laparosc Endosc Percutan Tech 2019 Aug;29(4):280-284

Department of Gastroenterology and Hepatology, The Second Affiliated Hospital of Harbin Medical University.

It is currently unclear whether endoscopic papillary balloon dilation (EPBD) is associated with increased severe postendoscopic retrograde cholangiopancreatography pancreatitis (PEP)-related morbidity owing to conflicting reports. This study aimed to investigate whether EPBD increases the risk of PEP and hyperamylasemia. Clinical data of patients with choledocholithiasis, treated at the Second Affiliated Hospital of Harbin Medical University from January 2015 to December 2016 were analyzed. Read More

Gastroenterol Res Pract 2019 15;2019:9675347. Epub 2019 Jan 15.

Department of Gastroenterology and Hepatology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511, Japan.

Background/aims: Endoscopic sphincterotomy (EST) is often performed before fully covered self-expandable metal stent (FCSEMS) placement in order to prevent pancreatitis. However, it is not clear whether EST prevents pancreatitis or affects other adverse events (AEs). This study is conducted to evaluate the necessity of EST before FCSEMS placement for distal malignant biliary strictures due to a pancreatic head tumor. Read More

Clin Cancer Res 2019 05 11;25(9):2699-2707. Epub 2019 Feb 11.

Memorial Sloan Kettering Cancer Center, New York, New York.

Purpose: To investigate tolerability, efficacy, and pharmacokinetics/pharmacodynamics of Debio 1347, a selective FGFR inhibitor.

Patients And Methods: This was a first-in-human, multicenter, open-label study in patients with advanced solid tumors harboring gene alterations. Eligible patients received oral Debio 1347 at escalating doses once daily until disease progression or intolerable toxicity. Read More

Pancreatology 2019 Mar 31;19(2):237-244. Epub 2019 Jan 31.

Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Centre, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address:

Background/objectives: Data estimating the prevalence of significant findings during the investigation of patients with Chronic Asymptomatic Pancreatic Hyperenzymemia (CAPH) are scanty and heterogeneous, and the diagnostic approach is therefore uncertain. The aim of this study was to meta-analyze pancreatic abnormalities detected at second-level imaging in patients with CAPH.

Methods: Pubmed database was searched until September 2018 for articles evaluating CAPH patients through MRI-Cholangio-Pancreatography with/without secretin (MRCP or s-MRCP) or Endoscopic Ultrasound (EUS). Read More

Zhonghua Yi Xue Za Zhi 2019 Jan;99(4):288-290

Department of Biliary Minimally Invasive Surgery, Affilated Zhongshan Hospital of Dalian University, Dalian 116001, China.

To investigate the efficacy, feasibility and safety of treatment of gallbladder and common bile duct stones treated through cholecystostomy tube. The clinical data of 17 patients with gallbladder and common bile duct stones treated through cholecystostomy tube from January 2012 to December 2016 was analyzed retrospectively. Seventeen patients were successfully treated with percutaneous transhepatic gallbladder (PTGD), and 88. Read More

Dig Dis 2019 17;37(3):255-261. Epub 2019 Jan 17.

Second Department of Internal Medicine, Osaka Medical College, Osaka, Japan.

Background: It is yet not clear whether differences in the contrast medium may affect post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).

Aim: The aim of this study was to evaluate the rate of PEP between high osmolality contrast medium (HOCM) and iso osmolar medium (IOCM) in a prospective, randomized, controlled trial.

Methods: Patients who were scheduled to undergo a diagnostic or therapeutic procedure under ERCP guidance were included. Read More

World J Clin Cases 2019 Jan;7(1):10-18

First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered anatomy has been a major challenge to gastrointestinal endoscopists with low success rates for reaching the target site as well as high complication rates. The knowledge of ERCP-related risk factors is important for reducing unexpected complications.

Aim: To identify ERCP-related risk factors for perforation in patients with surgically altered anatomy. Read More

Medicine (Baltimore) 2018 Dec;97(49):e13520

Department of Gynecology and Obstetrics, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China.

Rationale: Reports of malignant ovarian tumor with hyperamylasemia are very rare. We present a patient with hyperamylasemia who was diagnosed with a malignant ovarian tumor.

Patient Concerns: A 46-year-old woman was hospitalized complaining of a 2-day history of abdominal discomfort and fever. Read More

Med Sci Monit 2018 Nov 26;24:8544-8552. Epub 2018 Nov 26.

Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China (mainland).

BACKGROUND Postoperative pancreatitis is one of the most serious complications in endoscopic retrograde cholangiopancreatography (ERCP). To detect potential risk factors for post-ERCP hyperamylasemia and pancreatitis. MATERIAL AND METHODS We reviewed 1786 ERCP procedures in Zhongnan Hospital of Wuhan University from January 2015 to April 2018. Read More

J Robot Surg 2019 Oct 23;13(5):699-702. Epub 2018 Nov 23.

Department of Surgery, University of São Paulo, Hospital Nove de Julho, Rua Dona Adma Jafet 74 cj 102, São Paulo, 01308-050, Brazil.

Since the development of the robotic platform, the number of robotic-assisted surgeries has significantly increased. Robotic surgery has gained growing acceptance in recent years, expanding to pancreatic resection. Here, we report a total robotic resection of the uncinate process of the pancreas performed in a patient with a cystic neuroendocrine tumor. Read More

Pediatr Int 2019 Jan;61(1):23-30

Department of Allergy and Clinical Immunology, Shizuoka Children's Hospital, Shizuoka City, Shizuoka, Japan.

Background: Presently, little is known about the laboratory data several hours after oral food challenge (OFC) in patients with immunoglobulin (Ig)E-mediated immediate food allergy (FA).

Methods: One hundred and twelve subjects who underwent OFC at the present institute between 1 June 2016 and 31 March 2018, were enrolled in this study. Changes in laboratory data several hours after OFC were examined. Read More

J Gastroenterol Hepatol 2019 May 3;34(5):929-936. Epub 2018 Oct 3.

Department of Gastroenterology and Hepatology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan Province, China.

Background And Aim: This study aims to assess the clinical validity and safety of single-operator cholangioscopy system (SOCS) for the treatment of concomitant gallbladder stones and secondary common bile duct (CBD) stones.

Methods: This retrospective study included 10 consecutive patients who had small-sized stones (< 1 cm) in both the gallbladder and CBD; the patients underwent SOCS treatment from June 2016 to December 2016. The clinical validity of this minimally invasive surgery was determined by the operation success rate, stone removal rate, postoperative hospital stay, hospitalization cost, and contrast images before and after the operation. Read More

J Avian Med Surg 2018 09;32(3):232-239

A 25-year-old female yellow-naped Amazon parrot ( Amazona auropalliata) was presented for an acute onset of lethargy, ptyalism, and regurgitation. Results of hematologic testing and plasma biochemical analysis revealed severe leukopenia and heteropenia with toxic heterophils and marked hyperamylasemia and hypoproteinemia, consistent with gastrointestinal dysfunction. Survey radiograph findings were suggestive of coelomic effusion. Read More

Front Pharmacol 2018 29;9:704. Epub 2018 Jun 29.

Disgestive Diseases Institute Sharee Zedek Medical Center, Jerusalem, Israel.

Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is one of the major complications of ERCP. Thus, several non-invasive as well as invasive strategies have been investigated as preventative therapies for PEP with various efficacy. We enrolled any patients who underwent ERCP both at the Shaare Zedek Medical Center in Jerusalem and EMMS Nazareth hospital. Read More

Am Surg 2018 Jun;84(6):889-896

Postoperative pancreatic fistula (PF) remains one of the most significant complications after pancreaticoduodenectomy (PD). Recently, studies have suggested that post-PD serum hyperamylasemia (HA) may be a risk factor. In this study, we evaluate the relationship of pancreas texture and post-operative serum amylase levels in determining PF risk. Read More

World J Gastroenterol 2018 Jun;24(22):2392-2399

Department of Gastroenterology, School of Medicine, Fukushima Medical University, Fukushima 960-1247, Japan.

Aim: To investigate the location to which a pancreatic stent should be inserted to prevent post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).

Methods: Over a ten-year period at our hospital, 296 patients underwent their first ERCP procedure and had a pancreatic stent inserted; this study included 147 patients who had ERCP performed primarily for biliary investigation and had a pancreatic stent inserted to prevent PEP. We divided these patients into two groups: 131 patients with a stent inserted into the pancreatic head (head group) and 16 patients with a stent inserted up to the pancreatic body or tail (body/tail group). Read More

Evid Based Complement Alternat Med 2018 14;2018:9646937. Epub 2018 May 14.

Department of Physiology, Federal University of Sergipe, 49100-000 São Cristóvão, SE, Brazil.

We evaluated the effect of the hydroethanolic extract of fruits of (HEVm) in a model of acute pancreatitis (AP) in mice. AP was induced by two injections of L-arginine and animals were treated with HEVm (50, 100, and 200 mg/kg, p.o. Read More

Front Pediatr 2018 11;6:90. Epub 2018 Apr 11.

Section of Pediatrics Immunology and Rheumatology, Department of Pediatrics, University of Pisa, Pisa, Italy.

We describe the case of a 3-year child in which pancreatic and parotid gland involvement preceded the development of the classical clinical phenotype of a typical Kawasaki disease (KD). The child was referred to the Emergency Department with a story of 3 days of continuous fever associated with abdominal pain and bilaterally swelling in the parotid regions; laboratory evaluation identified markedly increased levels of total amylase, pancreatic amylase, lipase, and transaminase, and diagnosis of pancreatitis was posed. After 9 days of fever and persistence of the clinical features, the classical signs of KD appeared, and the child was treated with intravenous immunoglobulins (IVIG), showing a dramatic response with complete resolution of the clinical picture. Read More

BMJ Case Rep 2018 Apr 11;2018. Epub 2018 Apr 11.

Department of Gastroenterology, Ipswich Hospital NHS Trust, Ipswich, UK.

A 79-year-old man was admitted electively for investigation of weight loss. While he was an inpatient, he developed severe epigastric pain and an initial blood test revealed an acutely raised amylase (>2000) and deranged liver function tests. A contrast CT angiography showed a large haematoma adjacent to the duodenum, spreading in the retroperitoneal space, arising from a 2 cm bleeding pseudoaneurysm in the region of the gastroduodenal artery. Read More

J Gastroenterol Hepatol 2018 Oct 4;33(10):1804-1810. Epub 2018 May 4.

Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.

Background And Aim: Endoscopic retrograde cholangiopancreatography (ERCP) is associated with risk of complications. Methods to facilitate ductal cannulation may reduce complications. Intraduodenal acid infusion is a physiological approach to stimulate secretin release in human body and may facilitate cannulation. Read More

Clin Gastroenterol Hepatol 2018 09 7;16(9):e95-e96. Epub 2018 Apr 7.

Department of Gastroenterology, Reinier de Graaf Gasthuis, Delft, The Netherlands.

World J Surg 2018 10;42(10):3134-3142

Department of General Surgery, Division of HPB Surgery, Hospital Italiano de Buenos Aires, Juan D. Peron 4190, C1181ACH, Buenos Aires, Argentina.

Introduction: In laparoscopic transcystic common bile duct exploration (LTCBDE), the risk of acute pancreatitis (AP) is well recognized. The present study assesses the incidence, risk factors, and clinical impact of AP in patients with choledocholithiasis treated with LTCBDE.

Methods: A retrospective database was completed including patients who underwent LTCBDE between 2007 and 2017. Read More

Pancreatology 2018 Jun 10;18(4):370-378. Epub 2018 Mar 10.

Laboratory of Shock, Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, 410008, People's Republic of China. Electronic address:

Objective: To perform a meta-analysis of all available studies on the effect of prophylactic somatostatin administration on prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) and post-ERCP hyperamylasemia (PEHA).

Methods: Electronic databases, including PubMed, EMBASE, the Cochrane library, and the Science Citation Index were searched to retrieve relevant trials. Randomized, placebo-controlled trials in adult patients that compared somatostatin versus placebo in prevention of PEP were included. Read More

Case Rep Radiol 2017 18;2017:2879568. Epub 2017 Dec 18.

Hairmyres Hospital, Glasgow G75 8RG, UK.

Falciform ligament (remnant of umbilical vein) is an anatomical structure that connects the liver to the anterior abdominal wall. This case reports a rare clinical presentation of falciform ligament thrombosis as a consequence of acute gallstone pancreatitis, in a patient with noncirrhotic liver. A 55-year-old female with a history of cholelithiasis was admitted with abdominal pain. Read More