1,136 results match your criteria Hyperamylasemia


Association between chronic asymptomatic pancreatic hyperenzymemia and pancreatic ductal anomalies: a magnetic resonance cholangiopancreatography study.

Abdom Radiol (NY) 2019 Apr 3. Epub 2019 Apr 3.

Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: Elucidating the association between pancreatic ductal anomalies and chronic asymptomatic pancreatic hyperenzymemia using magnetic resonance cholangiopancreatography.

Methods: We conducted a single-center, retrospective, case-control study. The healthy community group comprised 554 subjects who participated in a paid, whole-body health checkup program. Read More

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http://dx.doi.org/10.1007/s00261-019-02004-4DOI Listing
April 2019
3 Reads

Preventive Effect of Somatostatin on Pancreatitis and Hyperamylasemia after Therapeutic ERCP.

J Coll Physicians Surg Pak 2019 Apr;29(4):400

Department of General Surgery, Pingshan District People's Hospital of Shenzhen, Shenzhen, Guangdong, 518118, China.

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http://dx.doi.org/10.29271/jcpsp.2019.04.400DOI Listing

Risks of Postendoscopic Retrograde Cholangiopancreatography Pancreatitis and Hyperamylasemia After Endoscopic Papillary Balloon Dilation: A Retrospective Analysis.

Surg Laparosc Endosc Percutan Tech 2019 Mar 11. Epub 2019 Mar 11.

Department of Gastroenterology and Hepatology, The Second Affiliated Hospital of Harbin Medical University.

It is currently unclear whether endoscopic papillary balloon dilation (EPBD) is associated with increased severe postendoscopic retrograde cholangiopancreatography pancreatitis (PEP)-related morbidity owing to conflicting reports. This study aimed to investigate whether EPBD increases the risk of PEP and hyperamylasemia. Clinical data of patients with choledocholithiasis, treated at the Second Affiliated Hospital of Harbin Medical University from January 2015 to December 2016 were analyzed. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000644DOI Listing
March 2019
1 Read

Endoscopic Sphincterotomy before Fully Covered Metal Stent Placement Is Not Required for Distal Malignant Biliary Stricture due to a Pancreatic Head Tumor.

Gastroenterol Res Pract 2019 15;2019:9675347. Epub 2019 Jan 15.

Department of Gastroenterology and Hepatology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511, Japan.

Background/aims: Endoscopic sphincterotomy (EST) is often performed before fully covered self-expandable metal stent (FCSEMS) placement in order to prevent pancreatitis. However, it is not clear whether EST prevents pancreatitis or affects other adverse events (AEs). This study is conducted to evaluate the necessity of EST before FCSEMS placement for distal malignant biliary strictures due to a pancreatic head tumor. Read More

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https://www.hindawi.com/journals/grp/2019/9675347/
Publisher Site
http://dx.doi.org/10.1155/2019/9675347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350600PMC
January 2019
13 Reads

A Phase I, Open-Label, Multicenter, Dose-escalation Study of the Oral Selective FGFR Inhibitor Debio 1347 in Patients with Advanced Solid Tumors Harboring Gene Alterations.

Clin Cancer Res 2019 Feb 11. Epub 2019 Feb 11.

Memorial Sloan Kettering Cancer Center, New York, New York.

To investigate tolerability, efficacy, and pharmacokinetics/pharmacodynamics of Debio 1347, a selective FGFR inhibitor. This was a first-in-human, multicenter, open-label study in patients with advanced solid tumors harboring gene alterations. Eligible patients received oral Debio 1347 at escalating doses once daily until disease progression or intolerable toxicity. Read More

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1959DOI Listing
February 2019
2 Reads

Chronic Asymptomatic Pancreatic Hyperenzymemia (CAPH): Meta-analysis of pancreatic findings at second-level imaging.

Pancreatology 2019 Mar 31;19(2):237-244. Epub 2019 Jan 31.

Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Centre, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address:

Background/objectives: Data estimating the prevalence of significant findings during the investigation of patients with Chronic Asymptomatic Pancreatic Hyperenzymemia (CAPH) are scanty and heterogeneous, and the diagnostic approach is therefore uncertain. The aim of this study was to meta-analyze pancreatic abnormalities detected at second-level imaging in patients with CAPH.

Methods: Pubmed database was searched until September 2018 for articles evaluating CAPH patients through MRI-Cholangio-Pancreatography with/without secretin (MRCP or s-MRCP) or Endoscopic Ultrasound (EUS). Read More

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http://dx.doi.org/10.1016/j.pan.2019.01.022DOI Listing
March 2019
3 Reads

[Clinical evaluation of gallbladder and common bile duct stones treated though cholecystostomy tube].

Zhonghua Yi Xue Za Zhi 2019 Jan;99(4):288-290

Department of Biliary Minimally Invasive Surgery, Affilated Zhongshan Hospital of Dalian University, Dalian 116001, China.

To investigate the efficacy, feasibility and safety of treatment of gallbladder and common bile duct stones treated through cholecystostomy tube. The clinical data of 17 patients with gallbladder and common bile duct stones treated through cholecystostomy tube from January 2012 to December 2016 was analyzed retrospectively. Seventeen patients were successfully treated with percutaneous transhepatic gallbladder (PTGD), and 88. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.04.010DOI Listing
January 2019
5 Reads

Can Iodixanol Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis? A Prospective, Randomized, Controlled Trial.

Dig Dis 2019 17;37(3):255-261. Epub 2019 Jan 17.

Second Department of Internal Medicine, Osaka Medical College, Osaka, Japan.

Background: It is yet not clear whether differences in the contrast medium may affect post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).

Aim: The aim of this study was to evaluate the rate of PEP between high osmolality contrast medium (HOCM) and iso osmolar medium (IOCM) in a prospective, randomized, controlled trial.

Methods: Patients who were scheduled to undergo a diagnostic or therapeutic procedure under ERCP guidance were included. Read More

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https://www.karger.com/Article/FullText/496349
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http://dx.doi.org/10.1159/000496349DOI Listing
March 2019
15 Reads

Risk factors for perforation during endoscopic retrograde cholangiopancreatography in post-reconstruction intestinal tract.

World J Clin Cases 2019 Jan;7(1):10-18

First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered anatomy has been a major challenge to gastrointestinal endoscopists with low success rates for reaching the target site as well as high complication rates. The knowledge of ERCP-related risk factors is important for reducing unexpected complications.

Aim: To identify ERCP-related risk factors for perforation in patients with surgically altered anatomy. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i1.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327124PMC
January 2019
2 Reads

Hyperamylasemia may indicate the presence of ovarian carcinoma: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13520

Department of Gynecology and Obstetrics, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China.

Rationale: Reports of malignant ovarian tumor with hyperamylasemia are very rare. We present a patient with hyperamylasemia who was diagnosed with a malignant ovarian tumor.

Patient Concerns: A 46-year-old woman was hospitalized complaining of a 2-day history of abdominal discomfort and fever. Read More

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http://dx.doi.org/10.1097/MD.0000000000013520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310503PMC
December 2018
19 Reads
5.723 Impact Factor

Risk Factors for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: Evidence from 1786 Cases.

Med Sci Monit 2018 Nov 26;24:8544-8552. Epub 2018 Nov 26.

Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China (mainland).

BACKGROUND Postoperative pancreatitis is one of the most serious complications in endoscopic retrograde cholangiopancreatography (ERCP). To detect potential risk factors for post-ERCP hyperamylasemia and pancreatitis. MATERIAL AND METHODS We reviewed 1786 ERCP procedures in Zhongnan Hospital of Wuhan University from January 2015 to April 2018. Read More

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https://www.medscimonit.com/abstract/index/idArt/913314
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http://dx.doi.org/10.12659/MSM.913314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278246PMC
November 2018
14 Reads

Robotic resection of the uncinate process of the pancreas.

J Robot Surg 2018 Nov 23. Epub 2018 Nov 23.

Department of Surgery, University of São Paulo, Hospital Nove de Julho, Rua Dona Adma Jafet 74 cj 102, São Paulo, 01308-050, Brazil.

Since the development of the robotic platform, the number of robotic-assisted surgeries has significantly increased. Robotic surgery has gained growing acceptance in recent years, expanding to pancreatic resection. Here, we report a total robotic resection of the uncinate process of the pancreas performed in a patient with a cystic neuroendocrine tumor. Read More

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http://dx.doi.org/10.1007/s11701-018-0898-yDOI Listing
November 2018
20 Reads

Neutrophilia and hyperamylasemia in patients with immediate food allergy.

Pediatr Int 2019 Jan;61(1):23-30

Department of Allergy and Clinical Immunology, Shizuoka Children's Hospital, Shizuoka City, Shizuoka, Japan.

Background: Presently, little is known about the laboratory data several hours after oral food challenge (OFC) in patients with immunoglobulin (Ig)E-mediated immediate food allergy (FA).

Methods: One hundred and twelve subjects who underwent OFC at the present institute between 1 June 2016 and 31 March 2018, were enrolled in this study. Changes in laboratory data several hours after OFC were examined. Read More

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http://dx.doi.org/10.1111/ped.13728DOI Listing
January 2019
24 Reads

Single-operator cholangioscopy for the treatment of concomitant gallbladder stones and secondary common bile duct stones.

J Gastroenterol Hepatol 2018 Sep 14. Epub 2018 Sep 14.

Department of Gastroenterology and Hepatology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan Province, China.

Background And Aim: This study aims to assess the clinical validity and safety of single-operator cholangioscopy system (SOCS) for the treatment of concomitant gallbladder stones and secondary common bile duct (CBD) stones.

Methods: This retrospective study included 10 consecutive patients who had small-sized stones (< 1 cm) in both the gallbladder and CBD; the patients underwent SOCS treatment from June 2016 to December 2016. The clinical validity of this minimally invasive surgery was determined by the operation success rate, stone removal rate, postoperative hospital stay, hospitalization cost, and contrast images before and after the operation. Read More

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http://doi.wiley.com/10.1111/jgh.14468
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http://dx.doi.org/10.1111/jgh.14468DOI Listing
September 2018
21 Reads
3.504 Impact Factor

Acute Necrotizing Pancreatitis in a Yellow-naped Amazon Parrot ( Amazona auropalliata).

J Avian Med Surg 2018 09;32(3):232-239

A 25-year-old female yellow-naped Amazon parrot ( Amazona auropalliata) was presented for an acute onset of lethargy, ptyalism, and regurgitation. Results of hematologic testing and plasma biochemical analysis revealed severe leukopenia and heteropenia with toxic heterophils and marked hyperamylasemia and hypoproteinemia, consistent with gastrointestinal dysfunction. Survey radiograph findings were suggestive of coelomic effusion. Read More

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http://dx.doi.org/10.1647/2017-268DOI Listing
September 2018
3 Reads

Chronic Use of Statins and Their Effect on Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.

Front Pharmacol 2018 29;9:704. Epub 2018 Jun 29.

Disgestive Diseases Institute Sharee Zedek Medical Center, Jerusalem, Israel.

Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is one of the major complications of ERCP. Thus, several non-invasive as well as invasive strategies have been investigated as preventative therapies for PEP with various efficacy. We enrolled any patients who underwent ERCP both at the Shaare Zedek Medical Center in Jerusalem and EMMS Nazareth hospital. Read More

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http://dx.doi.org/10.3389/fphar.2018.00704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034503PMC
June 2018
32 Reads

The Combination of Pancreas Texture and Postoperative Serum Amylase in Predicting Pancreatic Fistula Risk.

Am Surg 2018 Jun;84(6):889-896

Postoperative pancreatic fistula (PF) remains one of the most significant complications after pancreaticoduodenectomy (PD). Recently, studies have suggested that post-PD serum hyperamylasemia (HA) may be a risk factor. In this study, we evaluate the relationship of pancreas texture and post-operative serum amylase levels in determining PF risk. Read More

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June 2018
10 Reads

Pancreatic stents for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis should be inserted up to the pancreatic body or tail.

World J Gastroenterol 2018 Jun;24(22):2392-2399

Department of Gastroenterology, School of Medicine, Fukushima Medical University, Fukushima 960-1247, Japan.

Aim: To investigate the location to which a pancreatic stent should be inserted to prevent post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).

Methods: Over a ten-year period at our hospital, 296 patients underwent their first ERCP procedure and had a pancreatic stent inserted; this study included 147 patients who had ERCP performed primarily for biliary investigation and had a pancreatic stent inserted to prevent PEP. We divided these patients into two groups: 131 patients with a stent inserted into the pancreatic head (head group) and 16 patients with a stent inserted up to the pancreatic body or tail (body/tail group). Read More

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http://dx.doi.org/10.3748/wjg.v24.i22.2392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000294PMC
June 2018
6 Reads

Aiton Extract Ameliorates Inflammation and Hyperalgesia through Oxidative Stress Inhibition in Experimental Acute Pancreatitis.

Evid Based Complement Alternat Med 2018 14;2018:9646937. Epub 2018 May 14.

Department of Physiology, Federal University of Sergipe, 49100-000 São Cristóvão, SE, Brazil.

We evaluated the effect of the hydroethanolic extract of fruits of (HEVm) in a model of acute pancreatitis (AP) in mice. AP was induced by two injections of L-arginine and animals were treated with HEVm (50, 100, and 200 mg/kg, p.o. Read More

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http://dx.doi.org/10.1155/2018/9646937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976997PMC
May 2018
8 Reads

Typical Kawasaki Disease Presenting With Pancreatitis and Bilateral Parotid Gland Involvement: A Case Report and Literature Review.

Front Pediatr 2018 11;6:90. Epub 2018 Apr 11.

Section of Pediatrics Immunology and Rheumatology, Department of Pediatrics, University of Pisa, Pisa, Italy.

We describe the case of a 3-year child in which pancreatic and parotid gland involvement preceded the development of the classical clinical phenotype of a typical Kawasaki disease (KD). The child was referred to the Emergency Department with a story of 3 days of continuous fever associated with abdominal pain and bilaterally swelling in the parotid regions; laboratory evaluation identified markedly increased levels of total amylase, pancreatic amylase, lipase, and transaminase, and diagnosis of pancreatitis was posed. After 9 days of fever and persistence of the clinical features, the classical signs of KD appeared, and the child was treated with intravenous immunoglobulins (IVIG), showing a dramatic response with complete resolution of the clinical picture. Read More

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http://dx.doi.org/10.3389/fped.2018.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904203PMC
April 2018
8 Reads

Pseudoaneurysm of the gastroduodenal artery: an unusual cause for hyperamylasaemia.

BMJ Case Rep 2018 Apr 11;2018. Epub 2018 Apr 11.

Department of Gastroenterology, Ipswich Hospital NHS Trust, Ipswich, UK.

A 79-year-old man was admitted electively for investigation of weight loss. While he was an inpatient, he developed severe epigastric pain and an initial blood test revealed an acutely raised amylase (>2000) and deranged liver function tests. A contrast CT angiography showed a large haematoma adjacent to the duodenum, spreading in the retroperitoneal space, arising from a 2 cm bleeding pseudoaneurysm in the region of the gastroduodenal artery. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22388
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http://dx.doi.org/10.1136/bcr-2017-223882DOI Listing
April 2018
9 Reads

Impact of intraduodenal acetic acid infusion on pancreatic duct cannulation during endoscopic retrograde cholangiopancreatography: A double-blind, randomized controlled trial.

J Gastroenterol Hepatol 2018 Oct 4;33(10):1804-1810. Epub 2018 May 4.

Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.

Background And Aim: Endoscopic retrograde cholangiopancreatography (ERCP) is associated with risk of complications. Methods to facilitate ductal cannulation may reduce complications. Intraduodenal acid infusion is a physiological approach to stimulate secretin release in human body and may facilitate cannulation. Read More

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http://dx.doi.org/10.1111/jgh.14148DOI Listing
October 2018
12 Reads

Long-Standing Abdominal Complaints and Hyperamylasemia Due to Foreign Body Ingestion.

Clin Gastroenterol Hepatol 2018 Sep 7;16(9):e95-e96. Epub 2018 Apr 7.

Department of Gastroenterology, Reinier de Graaf Gasthuis, Delft, The Netherlands.

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http://dx.doi.org/10.1016/j.cgh.2017.09.039DOI Listing
September 2018
2 Reads

Acute Pancreatitis After Laparoscopic Transcystic Common Bile Duct Exploration: An Analysis of Predisposing Factors in 447 Patients.

World J Surg 2018 10;42(10):3134-3142

Department of General Surgery, Division of HPB Surgery, Hospital Italiano de Buenos Aires, Juan D. Peron 4190, C1181ACH, Buenos Aires, Argentina.

Introduction: In laparoscopic transcystic common bile duct exploration (LTCBDE), the risk of acute pancreatitis (AP) is well recognized. The present study assesses the incidence, risk factors, and clinical impact of AP in patients with choledocholithiasis treated with LTCBDE.

Methods: A retrospective database was completed including patients who underwent LTCBDE between 2007 and 2017. Read More

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http://dx.doi.org/10.1007/s00268-018-4611-0DOI Listing
October 2018
10 Reads

Effect of somatostatin on prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis and hyperamylasemia: A systematic review and meta-analysis.

Pancreatology 2018 Jun 10;18(4):370-378. Epub 2018 Mar 10.

Laboratory of Shock, Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, 410008, People's Republic of China. Electronic address:

Objective: To perform a meta-analysis of all available studies on the effect of prophylactic somatostatin administration on prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) and post-ERCP hyperamylasemia (PEHA).

Methods: Electronic databases, including PubMed, EMBASE, the Cochrane library, and the Science Citation Index were searched to retrieve relevant trials. Randomized, placebo-controlled trials in adult patients that compared somatostatin versus placebo in prevention of PEP were included. Read More

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http://dx.doi.org/10.1016/j.pan.2018.03.002DOI Listing
June 2018
10 Reads

A Rare Finding of Falciform Ligament Thrombosis as a Sequel of Acute Pancreatitis.

Case Rep Radiol 2017 18;2017:2879568. Epub 2017 Dec 18.

Hairmyres Hospital, Glasgow G75 8RG, UK.

Falciform ligament (remnant of umbilical vein) is an anatomical structure that connects the liver to the anterior abdominal wall. This case reports a rare clinical presentation of falciform ligament thrombosis as a consequence of acute gallstone pancreatitis, in a patient with noncirrhotic liver. A 55-year-old female with a history of cholelithiasis was admitted with abdominal pain. Read More

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http://dx.doi.org/10.1155/2017/2879568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748311PMC
December 2017
4 Reads

Rectally administered indomethacin to prevent post-ESWL-pancreatitis (RIPEP): study protocol for a randomized controlled trial.

Trials 2017 Nov 2;18(1):513. Epub 2017 Nov 2.

Department of Gastroenterology, Digestive Endoscopy Center, Changhai Hospital, the Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.

Background: Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is the first-line therapy for large pancreatic duct stones. Although it is a highly effective and safe procedure for the fragmentation of pancreatic stones, it is still not complication-free. Just like endoscopic retrograde cholangiopancreatography (ERCP), pancreatitis is the most common complication. Read More

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http://dx.doi.org/10.1186/s13063-017-2250-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667485PMC
November 2017
28 Reads

Multicenter prospective evaluation study of endoscopic ultrasound-guided hepaticogastrostomy combined with antegrade stenting (with video).

Dig Endosc 2018 Mar 22;30(2):252-259. Epub 2017 Nov 22.

Therapeutic Endoscopic Ultrasound Group: TEUS, Takatuki, Japan.

Background And Aim: Endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS) is often indicated for advanced stage patients. Therefore it is important to prevent adverse events associated with EUS-HGS procedures and obtain long stent patency. EUS-guided antegrade stenting (AS) has been developed as an advanced technique. Read More

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http://dx.doi.org/10.1111/den.12976DOI Listing
March 2018
24 Reads
1.989 Impact Factor

The modified pancreatic stent system for prevention of post-ERCP pancreatitis: a case-control study.

BMC Gastroenterol 2017 Oct 18;17(1):108. Epub 2017 Oct 18.

Department of Biliary Minimally Invasive Surgery, Affiliated Zhongshan Hospital of Dalian University, No, 6. Jiefang Road, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.

Background: Prophylactic pancreatic stents after endoscopic retrograde cholangiopancreatography (ERCP) can help prevent post-ERCP pancreatitis. However most of the pancreatic stents need to be removed by another ERCP. The aim of this observational study was to investigate the feasibility and effectiveness of the modified pancreatic stent system for prevention of post-ERCP pancreatitis. Read More

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http://dx.doi.org/10.1186/s12876-017-0661-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648421PMC
October 2017
10 Reads

Nasobiliary drainage can reduce the incidence of post-ERCP pancreatitis after papillary large balloon dilation plus endoscopic biliary sphincterotomy: a randomized controlled trial.

Scand J Gastroenterol 2018 Jan 18;53(1):114-119. Epub 2017 Oct 18.

b Department of Biliary-Pancreatic Surgery , Anhui Provincial Hospital Affiliated with Anhui Medical University , Hefei , Anhui , China.

Background And Aims: Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis can be reduced following endoscopic papillary balloon dilation with the placement of an endoscopic nasobiliary drainage (ENBD) catheter. The aim of this study was to determine whether the placement of an ENBD reduces the risk of post-ERCP pancreatitis following endoscopic papillary large balloon dilation together with endoscopic biliary sphincterotomy.

Methods: A total of 160 patients with bile duct stones were randomly assigned (1:1) to an ENBD group or no-ENBD group. Read More

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http://dx.doi.org/10.1080/00365521.2017.1391329DOI Listing
January 2018
22 Reads

Interventional endoscopic ultrasound for a symptomatic pseudocyst secondary to gastric heterotopic pancreas.

World J Gastroenterol 2017 Sep;23(34):6365-6370

Department of Gastroenterology, Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou 310000, Zhejiang Province, China.

Heterotopic pancreas (HP) is a relatively uncommon entity that is defined as pancreatic tissue without a true anatomical or vascular connection to the pancreas. HP does not cause symptoms in most cases but can occasionally produce various manifestations, including nausea, vomiting, abdominal pain, and even heterotopic pancreatitis. Here, we report an unusual case in which heterotopic pancreatitis complicated by the formation of a pseudocyst that caused gastric outlet obstruction was diagnosed based on serum hyperamylasemia and findings from endoscopic ultrasonography (EUS)-guided fine needle aspiration (EUS-FNA) cytology. Read More

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http://dx.doi.org/10.3748/wjg.v23.i34.6365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603504PMC
September 2017
51 Reads

Evidences supporting the vascular etiology of post-double balloon enteroscopy pancreatitis: Study in porcine model.

World J Gastroenterol 2017 Sep;23(34):6201-6211

Department of Gastroenterology, Small Bowel Unit, Morales Meseguer Hospital, 3008 Murcia, Spain.

Double balloon enteroscopy (DBE) is an endoscopic technique broadly used to diagnose and treat small bowel diseases. Among the associated complications of the oral DBE, post-procedure pancreatitis has taken the most attention due to its gravity and the thought that it might be associated to the technique itself and anatomical features of the pancreas. However, as the etiology has not been clarified yet, this paper aims to review the published literature and adds new results from a porcine animal model. Read More

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http://dx.doi.org/10.3748/wjg.v23.i34.6201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603486PMC
September 2017
45 Reads

Prophylactic ulinastatin administration for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: A meta-analysis.

Exp Ther Med 2017 Oct 8;14(4):3036-3056. Epub 2017 Aug 8.

Department of Surgery, Shanghai Jiading Central Hospital, Shanghai 201800, P.R. China.

The objective of the present study was to perform a meta-analysis of all available studies on the effect of prophylactic ulinastatin administration on preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). The PubMed, Web of Knowledge and Chinese National Knowledge Infrastructure databases were searched to identify all relevant studies published in English or Chinese prior to April 2016. Cochrane Review Manager was used to calculate the pooled risk ratio (RR) and 95% confidence interval (CI) to determine the effect of prophylactic ulinastatin on PEP, post-ERCP hyperamylasemia (PEHA) and post-ERCP abdominal pain. Read More

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http://dx.doi.org/10.3892/etm.2017.4910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613208PMC
October 2017
10 Reads

Laparoscopic hepatectomy combined with endoscopic papillary balloon dilation for complex bile duct stones.

ANZ J Surg 2018 Jun 13;88(6):E522-E525. Epub 2017 Aug 13.

Department of Hepatobiliary Surgery, Taizhou Hospital of Zhejiang Province, Taizhou, China.

Background: We evaluated the feasibility and efficacy of laparoscopic hepatectomy (LH) combined with endoscopic papillary balloon dilation (EPBD) for removing intra- and extrahepatic bile duct stones.

Methods: A total of 26 patients with intra- and extrahepatic bile duct stones underwent LH and EPBD. Selective hemi-hepatic vascular occlusion was used to complete the LH. Read More

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http://dx.doi.org/10.1111/ans.14132DOI Listing
June 2018
11 Reads

Celecoxib Oral Administration for Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Randomized Prospective Trial.

Pancreas 2017 08;46(7):880-886

From the Department of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka, Japan.

Objectives: Rectal nonsteroidal anti-inflammatory drugs have reported promising prophylactic activity in post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). Conversely, cyclooxygenase-2 enzyme has been suggested to contribute to experimental acute pancreatitis. The aim of this study was to evaluate the efficacy of oral administration of celecoxib, a cyclooxygenase-2 inhibitor, for the prevention of PEP. Read More

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http://dx.doi.org/10.1097/MPA.0000000000000852DOI Listing
August 2017
13 Reads

Classification of pancreaticobiliary maljunction and clinical features in children.

J Hepatobiliary Pancreat Sci 2017 Aug 31;24(8):449-455. Epub 2017 Jul 31.

The Committee on Diagnostic Criteria of the Japanese Study Group on Pancreaticobiliary Maljunction, The Com, The Com.

Background: In 2015, the Committee on Diagnostic Criteria of the Japanese Study Group on Pancreaticobiliary Maljunction (PBM) proposed a classification of PBM into four types: (A) stenotic type, (B) non-stenotic type, (C) dilated channel type, and (D) complex type. To validate this classification and clarify the clinical features of the four types of PBM, a retrospective multicenter study was conducted.

Methods: The study group of 317 children with PBM was divided into the four types of PBM. Read More

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http://dx.doi.org/10.1002/jhbp.485DOI Listing
August 2017
9 Reads

The Efficiency of Aggressive Hydration With Lactated Ringer Solution for the Prevention of Post-ERCP Pancreatitis: A Systematic Review and Meta-analysis.

J Clin Gastroenterol 2017 Sep;51(8):e68-e76

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Jiangxi, P.R. China.

Background: As shown in studies, aggressive hydration during the perioperative period of endoscopic retrograde cholangiopancreatography (ERCP) effectively prevents post-ERCP pancreatitis (PEP). We conducted a systematic review and meta-analysis to evaluate the clinical effectiveness and safety of aggressive hydration with lactated Ringer solution at preventing PEP.

Materials And Methods: We searched all relevant research from PubMed, the Cochrane Library, Embase, the Web of Science, ClinicalTrial. Read More

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http://dx.doi.org/10.1097/MCG.0000000000000856DOI Listing
September 2017
9 Reads

Value of Raw Rhubarb Solution in the Precaution of Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis in Patients with High-Risk Factors: A Predictive Random Compared Research in One Center.

Dig Dis Sci 2017 04 13;62(4):1043-1050. Epub 2017 Feb 13.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.

Background And Aims: Post-ERCP pancreatitis and hyperamylasemia are common complications of endoscopic retrograde cholangiopancreatography (ERCP), especially in high-risk patients. The aim of this study is to evaluate whether a raw rhubarb solution can reduce the incidence of PEP and post-ERCP hyperamylasemia.

Methods: From October 2012 to October 2013, 2100 patients received ERCP in our Endoscopic Center. Read More

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http://dx.doi.org/10.1007/s10620-017-4464-7DOI Listing
April 2017
19 Reads

Hyperamylasaemia and gastrointestinal bleeding as the first manifestation of jejunal ectopic pancreas.

Gastroenterol Hepatol 2018 02 7;41(2):113-114. Epub 2017 Feb 7.

Gastroenterology Department, Hospital de Galdakao, Galdakao, Vizcaya, Spain.

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http://dx.doi.org/10.1016/j.gastrohep.2016.12.004DOI Listing
February 2018
6 Reads

Aggressive Hydration With Lactated Ringer Solution in Prevention of Postendoscopic Retrograde Cholangiopancreatography Pancreatitis: A Meta-analysis of Randomized Controlled Trials.

J Clin Gastroenterol 2017 Mar;51(3):e17-e26

*Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China †Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, Guangdong Province.

Background: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). The results of previous studies evaluating aggressive hydration with lactated Ringer solution for reducing the incidence of post-ERCP pancreatitis (PEP) are inconsistent.

Aim: We performed a meta-analysis to determine whether aggressive hydration with lactated Ringer solution reduced PEP. Read More

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http://dx.doi.org/10.1097/MCG.0000000000000781DOI Listing
March 2017
38 Reads

Role of Somatostatin in Preventing Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis: An Update Meta-analysis.

Front Pharmacol 2016 15;7:489. Epub 2016 Dec 15.

Department of Gastroenterology, Fu Xing Hospital, Capital Medical University Beijing, China.

Acute pancreatitis is the most common serious complication of endoscopic retrograde cholangiopancreatography (ERCP). Although, somatostatin (SOM) has been used in the prevention of post-ERCP pancreatitis (PEP), the efficacy of SOM remains inconsistent. Electronic databases, including PubMed/MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library), and the Science Citation Index were searched to retrieve relevant studies. Read More

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http://journal.frontiersin.org/article/10.3389/fphar.2016.00
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http://dx.doi.org/10.3389/fphar.2016.00489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156829PMC
December 2016
13 Reads

[Value of integrated pancreatic and biliary stents for prevention of post-ERCP pancreatitis].

Zhonghua Yi Xue Za Zhi 2016 Dec;96(46):3710-3714

Department of Biliary Minimally Invasive Surgery, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.

To investigate the value of integrated pancreatic and biliary stents for prevention of post-Endoscopic Retrograde Cholangiopancreatography (ERCP) pancreatitis. The clinical data of patients whom had pancreatic stents for prevention of post-ERCP pancreatitis from December 2013 to October 2015 were retrospectively analyzed. The clinical effect and complication were compared between straight pancreatic stents group and integrated pancreatic and biliary stents group. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2016.46.004DOI Listing
December 2016
5 Reads

Genetic Susceptibility in Acute Pancreatitis: Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants.

Pancreas 2017 01;46(1):71-76

From the *Centro Hospitalar de Lisboa Central, Hospital Santo António dos Capuchos, Alameda de Santo António dos Capuchos; †NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa; and ‡Centre for Toxicogenomics and Human Health, Genetics, Oncology and Human Toxicology, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.

Objectives: Genetic testing could play a critical role in diagnosis and prognosis of acute pancreatitis (AP) and guide effective therapeutic interventions. We hypothesized that genetic polymorphisms in apoptosis and oxidative stress genes could determine incidence or severity in AP.

Methods: We conducted a hospital-based case-control study in a white Portuguese population (133 AP patients and 232 age- and sex-matched healthy controls) to evaluate the role of 15 gene polymorphisms (2 deletions and 13 single nucleotide polymorphisms [SNPs]) in oxidative stress (GSTM1, GSTT1, GSTP1) and apoptosis genes (CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, TP53) in AP. Read More

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http://dx.doi.org/10.1097/MPA.0000000000000707DOI Listing
January 2017
17 Reads
2 Citations
2.960 Impact Factor

Which Mechanism is Effective on the Hyperamylasaemia After Coronary Artery Bypass Surgery?

Heart Lung Circ 2017 May 15;26(5):504-508. Epub 2016 Nov 15.

Dokuz Eylül University Faculty of Medicine, Department of Cardiovascular Surgery, İzmir, Turkey.

Background And Aim: Acute pancreatitis is one of the less frequently diagnosed lethal abdominal complications of cardiac surgery. The incidence of early postoperative period hyperamylasaemia was reported to be 30-70% of patients who underwent coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). The mechanism of pancreatic enzyme elevation after cardiac surgery is not clear. Read More

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http://dx.doi.org/10.1016/j.hlc.2016.09.006DOI Listing
May 2017
50 Reads

Pancreatitis After Pancreatoduodenectomy Predicts Clinically Relevant Postoperative Pancreatic Fistula.

J Gastrointest Surg 2017 02 28;21(2):330-338. Epub 2016 Nov 28.

Clinic for General and Visceral Surgery, Department of Surgery, University of Freiburg, Freiburg, Germany.

Background: Morbidity after pancreas resection is still high with postoperative pancreatic fistulas (POPF) being the most frequent complication. However, exocrine insufficiency seems to protect from POPF. In clinical practice, patients showing increased postoperative systemic amylase concentrations appear to frequently develop POPF. Read More

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http://dx.doi.org/10.1007/s11605-016-3305-xDOI Listing
February 2017
7 Reads

Does the abdominal ultrasonography reliable in the diagnosis of postoperative pancreatic fistula after pancreaticoduodenectomy in the first postoperative week?

Ann Surg Treat Res 2016 Nov 31;91(5):254-259. Epub 2016 Oct 31.

Department of General Surgery, Istanbul Training and Research Hospital, Istanbul, Turkey.

Purpose: We evaluated the efficacy of ultrasonography (US) in the early postoperative period after pancreaticoduodenectomy (PD) to diagnose postoperative-pancreatic-fistula (POPF). Early diagnosis is important to prevent POPF-dependent mortality after PD. The value of radiological modalities for early diagnosing POPF is not clear. Read More

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http://dx.doi.org/10.4174/astr.2016.91.5.254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107420PMC
November 2016
14 Reads

Risk Factors of Acute Pancreatitis in Oral Double Balloon Enteroscopy.

Acta Medica (Hradec Kralove) 2016;59(3):84-90. Epub 2016 Sep 1.

2nd Department of Medicine - Gastroenterology, Charles University, Faculty of Medicine in Hradec Králové, University Teaching Hospital, Hradec Králové, Czech Republic.

Double balloon enteroscopy (DBE) was introduced 15 years ago. The complications of diagnostic DBE are rare, acute pancreatitis is most redoubtable one (incidence about 0.3%). Read More

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http://dx.doi.org/10.14712/18059694.2016.95DOI Listing
June 2017
8 Reads

Intravenous injection of low-dose flurbiprofen axetil for preventing post-ERCP pancreatitis in high-risk patients: An interim analysis of the trial.

Endosc Int Open 2016 Oct 21;4(10):E1078-E1082. Epub 2016 Sep 21.

Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.

Several meta-analyses and randomized control trials have demonstrated the efficacy of rectal nonsteroidal anti-inflammatory drugs for preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). Diclofenac or indomethacin was administered at a dose of 100 mg in those studies, which may be too high for Asian population. In addition, rectal administration can be considered complicated. Read More

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http://dx.doi.org/10.1055/s-0042-115172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063645PMC
October 2016
13 Reads