148,615 results match your criteria Hydrops Fetalis


Atypical Prenatal Ultrasound Presentation and Neuropathological Findings in a Neonate With Alpha Thalassemia Major: A Case Report.

Pediatr Dev Pathol 2018 Dec 14:1093526618817655. Epub 2018 Dec 14.

1 Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada.

Alpha thalassemia major is a hemoglobinopathy caused by the inactivation or deletion of all 4 α-globin alleles. We describe a case of α-thalassemia major with atypical ultrasound and neuropathological findings. The mother had her first prenatal visit at 27 4/7 gestational weeks. Read More

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December 2018

NEW PROPOSAL FOR THE PATHOPHYSIOLOGY OF TYPE 3 NEOVASCULARIZATION AS BASED ON MULTIMODAL IMAGING FINDINGS.

Authors:
Richard F Spaide

Retina 2018 Dec 6. Epub 2018 Dec 6.

Vitreous, Retina, Macula Consultants of New York, New York.

Purpose: To investigate the imaging characteristics of early Type 3 neovascularization and propose a new pathophysiologic sequence for early disease.

Methods: Patients were evaluated with a comprehensive ophthalmologic examination to include fundus photography, optical coherence tomography, optical coherence tomography angiography, fluorescein angiography, and volume-rendered optical coherence tomography angiography. Relevant literature was also reviewed. Read More

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December 2018

Diagnostic Value of the Magnetic Resonance Imaging With Intratympanic Gadolinium Administration (IT-Gd MRI) Versus Audio-Vestibular Tests in Menière's Disease: IT-Gd MRI Makes the Difference.

Otol Neurotol 2018 Dec 13. Epub 2018 Dec 13.

Albers-Schönberg Institute for Radiology in Hamburg, Germany.

Objective: Our aim was to evaluate the validity and reliability of clinically relevant tests in the diagnosis of Menière's disease (MD) according to the criteria formulated during 2015 as well as their efficacy in detecting endolymphatic hydrops (EH). The focus was on: three-dimensional fluid-attenuated inversion recovery-SPectral Attenuated Inversion Recovery (3D-FLAIR-SPAIR) sequences using 3 Tesla magnetic resonance imaging (3T MRI) performed 24 hours after intratympanic Gadolinium injection (IT-Gd) in comparison with the functional tests pure tone audiometry (PTA), caloric test, video head impulse test (vHIT), and cervical-vestibular-evoked-myogenic-potentials (cVEMP).

Study Design: Retrospective study. Read More

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December 2018

The impact of anti-vascular endothelial growth factor agents on visual impairment/blindness prevention in patients with diabetic macular edema and on associated patient and caregiver burden in Japan.

J Med Econ 2018 Dec 14:1-28. Epub 2018 Dec 14.

e Market Access, Health Economics and Outcomes Research , Bayer Yakuhin, Ltd , Tokyo , Japan.

Aims: To estimate the impact of anti-vascular endothelial growth factor (VEGF) agents on visual impairment and blindness avoided in patients with diabetic macular edema (DME) and on associated patient and caregiver productivity loss in Japan.

Methods: We compared the impact of current care (estimated at 53.8% utilization of anti-VEGF agents using current data) with that of hypothetical care (characterized by a higher utilization of anti-VEGF agents [80. Read More

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December 2018
1 Read

A case of severe hypothyroidism causing cardiac tamponade associated with lithium intoxication.

J Cardiol Cases 2013 Jul 24;8(1):e42-e45. Epub 2013 Apr 24.

Department of Internal Medicine, Tokushima Prefectural Central Hospital, 1-10-3 Kuramoto, Tokushima 770-8539, Japan.

A 70-year-old man was referred to our emergency department for shortness of breath on exertion and systemic edema. He had been taking lithium carbonate for 2 years (500 mg/day over previous 3 months) for bipolar disorder diagnosed at age 60. He was diagnosed with hypothyroidism accompanied by Hashimoto's disease 2 weeks before hospitalization. Read More

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Effect of vasodilators in patient with pulmonary hypertension associated with hemolytic anemia.

J Cardiol Cases 2012 Sep 5;6(3):e75-e77. Epub 2012 Jun 5.

Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Pulmonary arterial hypertension (PAH) has been described to associate with hemolytic anemia in updated clinical classification of pulmonary hypertension. A 56-year-old woman, diagnosed with warm antibody autoimmune hemolytic anemia (AIHA), was treated with oral corticosteroids at the Department of Hematology, Osaka University Hospital for 30 years. Her AIHA worsened 3 months before the admission, and she was treated with rituximab and cyclosporine in combination with prednisolone. Read More

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September 2012
1 Read

Successful adaptive servo-ventilation for patients with acute cardiogenic pulmonary edema due to severe aortic stenosis.

J Cardiol Cases 2010 Oct 12;2(2):e115-e118. Epub 2010 Jun 12.

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan.

A 60-year-old woman with severe aortic stenosis (AS) and congenital bicuspid aortic valve was admitted to our hospital due to cardiogenic pulmonary edema. Noninvasive adaptive servo-ventilation (ASV) improved her symptoms and respiratory status. It was associated with favorable hemodynamic effects including an increase in cardiac output and a decrease in pulmonary vascular resistance without alternating systemic blood pressure. Read More

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October 2010

Acute pulmonary edema secondary to a hidden hypertensive emergency.

J Cardiol Cases 2016 Aug 20;14(2):56-58. Epub 2016 Apr 20.

Cardiology Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain.

Severe stenosis of the subclavian artery is a rare clinical finding, even more so for bilateral existence of the condition. Subclavian artery stenosis leads to erroneously normal or even low blood pressure values when measured at the brachial artery on the ipsilateral side. The poor control of blood pressure may cause cardiovascular complications such as heart failure and acute pulmonary edema without the patient having high blood pressure in the arms. Read More

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Complete atrioventricular block improved by balloon aortic valvuloplasty for severe aortic stenosis: Usefulness of sheathless technique in the retrograde approach.

J Cardiol Cases 2016 Jun 10;13(6):181-184. Epub 2016 Mar 10.

Division of Cardiology, Matsuyama Red Cross Hospital, Matsuyama, Japan.

An 86-year-old man was admitted to our hospital for treatment of congestive heart failure with severe aortic stenosis and advanced atrioventricular (AV) block. Despite pharmacological therapy, he developed complete AV block and resultant acute pulmonary edema requiring temporary pacing and tracheal intubation. We urgently performed retrograde balloon aortic valvuloplasty (BAV) with a sheathless technique. Read More

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Worsening of proteinuria caused by combination therapy of hypertonic saline and low-dose furosemide for treatment of acute decompensated heart failure with overt diabetic nephropathy.

J Cardiol Cases 2015 Dec 28;12(6):188-191. Epub 2015 Aug 28.

Cardiovascular Division, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.

A combination of hypertonic saline and furosemide has been proposed as a new therapeutic approach for treating acute decompensated heart failure (ADHF). The advantages of this combination have not only been demonstrated in ADHF but also in refractory ascites due to liver cirrhosis. However, the therapeutic effects of this regimen have never been evaluated in ADHF with overt diabetic nephropathy (ODN). Read More

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December 2015

Transient acute left ventricular dysfunction post-pericardiocentesis for cardiac tamponade.

J Cardiol Cases 2015 Oct 27;12(4):133-137. Epub 2015 Jul 27.

National Heart Centre, Singapore.

A rare but serious complication of pericardiocentesis is the development of transient left ventricular dysfunction. In this report, we present a case of a 65-year-old male patient with cardiac tamponade who suffered from acute left ventricular heart failure post-pericardiocentesis. < Acute left ventricular dysfunction is a rare but serious complication of pericardiocentesis. Read More

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October 2015

Budd-Chiari syndrome after liver transplantation resulting from inferior vena cava occlusion at the suture line.

J Cardiol Cases 2015 Mar 6;11(3):73-77. Epub 2015 Jan 6.

Ochsner Medical Center, John Ochsner Heart and Vascular Institute, New Orleans, LA, USA.

A 64-year-old male with Budd-Chiari syndrome (BCS) due to inferior vena cava (IVC) occlusion after liver transplant presented with massive ascites and lower extremity edema. He was found to have chronic total occlusion of the supra-hepatic IVC with thrombosis in the infra-hepatic IVC, hepatic, renal, and iliac veins. Attempts to recanalize the occlusion by multiple operators failed. Read More

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A case of massive pericardial effusion associated with hypocalcemic cardiomyopathy.

J Cardiol Cases 2014 Aug 11;10(2):58-61. Epub 2014 Jun 11.

Department of Cardiology and Hematology, Fukushima Medical University, Fukushima, Japan.

A 60-year-old woman with a 6-year history of numbness in her hands was admitted to hospital with dyspnea. Laboratory findings showed the elevation of creatine kinase (creatine kinase MB isoenzyme was less than 4 IU/l). Chest X-ray revealed cardiomegaly and pulmonary edema. Read More

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A rare case of pericardial hemangioma with bloody pericardial effusion.

J Cardiol Cases 2010 Aug 1;2(1):e15-e19. Epub 2010 Mar 1.

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Hyogo, Japan.

A 78-year-old woman presented with leg edema and exertional dyspnea. Echocardiography revealed a smooth-surfaced mass adjacent to the left atrium in the pericardial cavity with a massive pericardial effusion. Pericardiocentesis resulted in the drainage of a bloody effusion. Read More

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A case of transient apical hypertrophy associated with coronary vasospasm.

J Cardiol Cases 2017 Jan 17;15(1):14-17. Epub 2016 Oct 17.

Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.

A 49-year-old woman was admitted to our hospital because of repeated loss of consciousness. On arrival, she was in cardiopulmonary arrest associated with arrhythmia of Torsades de pointes, and recovered from it after cardiopulmonary resuscitation and defibrillation. The administration of a β-blocker and amiodarone was initiated to prevent ventricular tachycardia. Read More

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January 2017

Acute myocarditis in bodybuilder from coxsackievirus and thyrotoxicosis.

J Cardiol Cases 2016 Oct 20;14(4):123-126. Epub 2016 Jul 20.

Department of Cardiology, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.

A 25-year-old male with no past medical history presented with 1 day of chest pain. The patient had exercised with high intensity for a bodybuilding competition. He had fever, malaise, sore throat, and cough 1 week before presentation. Read More

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October 2016

Impact of low-dose prednisolone on refractory pitting edema manifesting remitting seronegative symmetrical synovitis with pitting edema syndrome.

J Cardiol Cases 2016 Oct 15;14(4):119-122. Epub 2016 Jul 15.

Department of Cardiology, Nishinomiya Municipal Central Hospital, Nishinomiya, Japan.

We encountered an elderly male patient who after cardiac surgery for mitral stenosis had refractory pitting edema in both legs involving painful leg joints after a 1-month history of waxing and waning arthralgia. His family doctor had prescribed a combination of diuretics, 40 mg furosemide and 25 mg spironolactone; however, pitting edema in his lower legs persisted. He was diagnosed with worsening of congestive heart failure because of a previous cardiac surgery and was transferred to our hospital. Read More

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October 2016

Interferon-α-induced retinopathy in chronic hepatitis C treatment: summary, considerations, and recommendations.

Graefes Arch Clin Exp Ophthalmol 2018 Dec 13. Epub 2018 Dec 13.

Department of Ophthalmology and Vision Sciences, Princess Margaret Hospital/University Health Network, University of Toronto, 610 University Avenue, Toronto, ON, M5G 2M9, Canada.

Interferons are cytokines that regulate the host's response to viral infection, particularly in the setting of the immunologic response to the hepatitis C virus (HCV). While the virus has the ability to evade the host's innate and specific immunity, exogenous interferon-α with combined ribavirin, treatments have been found to achieve a significant sustained viral response in subgroups of patients with chronic HCV. One of the major side effects of interferon-α is an ocular retinopathy characterized by flame-shaped hemorrhages and cotton wool spots visualized on funduscopic examination. Read More

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December 2018

Efficacy of SMTP-7, a small-molecule anti-inflammatory thrombolytic, in embolic stroke in monkeys.

Pharmacol Res Perspect 2018 Dec 5;6(6):e00448. Epub 2018 Dec 5.

Department of Applied Biological Science Tokyo Noko University (Tokyo University of Agriculture and Technology) Tokyo Japan.

SMTP-7 ( triprenyl phenol-7) is a small molecule that promotes thrombolysis and suppresses inflammation possibly through plasminogen modulation and soluble epoxide hydrolase (sEH) inhibition, respectively. Here, we demonstrate an efficacy of SMTP-7 in a severe embolic stroke model in monkeys. The middle cerebral artery was embolized by an autologous blood clot. Read More

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December 2018

Posterior fossa choroid plexus papilloma with focal ependymal differentiation in an adult patient: A case report and literature review.

Radiol Case Rep 2019 Mar 4;14(3):304-308. Epub 2018 Dec 4.

Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.

Choroid plexus papillomas (CPPs) are rare neoplasms classified as World Health Organization grade I tumors. CPPs containing other tissues have occasionally been documented in the literature. However, few of these previous reports have provided clinical and radiological information. Read More

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Deletion of macro domain containing 2(MACRO D2) associated with transient hydrops fetalis.

Taiwan J Obstet Gynecol 2018 Dec;57(6):897-898

Trakya University, Faculty of Medicine, Department of Perinatology, Turkey.

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December 2018
2 Reads

Cardiovascular Magnetic Resonance in Nonischemic Myocardial Inflammation: Expert Recommendations.

J Am Coll Cardiol 2018 Dec;72(24):3158-3176

Heidelberg University Hospital, Heidelberg, Germany; Department of Cardiology, McGill University Health Centre, Montreal, Canada; Department of Diagnostic Radiology, McGill University Health Centre, Montreal, Canada. Electronic address:

This JACC Scientific Expert Panel provides consensus recommendations for an update of the cardiovascular magnetic resonance (CMR) diagnostic criteria for myocardial inflammation in patients with suspected acute or active myocardial inflammation (Lake Louise Criteria) that include options to use parametric mapping techniques. While each parameter may indicate myocardial inflammation, the authors propose that CMR provides strong evidence for myocardial inflammation, with increasing specificity, if the CMR scan demonstrates the combination of myocardial edema with other CMR markers of inflammatory myocardial injury. This is based on at least one T2-based criterion (global or regional increase of myocardial T2 relaxation time or an increased signal intensity in T2-weighted CMR images), with at least one T1-based criterion (increased myocardial T1, extracellular volume, or late gadolinium enhancement). Read More

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December 2018

HPLC-ESI-MS/MS Profiling of Polyphenolics of a Leaf Extract from (Zingiberaceae) and Its Anti-Inflammatory, Anti-Nociceptive, and Antipyretic Activities In Vivo.

Molecules 2018 Dec 7;23(12). Epub 2018 Dec 7.

Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, 44883-2462 Heidelberg, Germany.

Reactive oxygen species (ROS) have been linked to several health conditions, among them inflammation. Natural antioxidants may attenuate this damage. Our study aimed to investigate the chemical composition of a methanol leaf extract from and its possible antioxidant, anti-inflammatory, anti-nociceptive, and antipyretic effects. Read More

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December 2018

Perforation of small intestine secondary to metastatic lung adenocarcinoma: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13469

Department of Emergency Surgery, Union Hospital.

Rationale: About 50% of patients with a diagnosis of nonsmall cell lung carcinoma exhibit metastatic disease at the time of diagnosis. The preferential sites of extrapulmonary spread are the lymph nodes, liver, brain, adrenal glands, and bones; gastrointestinal tract perforation secondary to metastatic lung cancer is extremely rare.

Patient Concerns: A 60-year-old male nonsmoker patient presented with a 20-day history of facial, neck, and right upper limb edema. Read More

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December 2018

Secondary lymphedema after high ligation of the great saphenous vein surgery: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13379

Department of Vascular Surgery, Yuhuangding Hospital, Qingdao University.

A 56-year-old male patient with secondary lymphedema in a single lower extremity presented to our hospital.He received high ligation of great saphenous vein 3 years ago. Severe infection was observed in affected limb on postoperative day 10, and rapidly progressive pain and erythema spreading to inguinal region. Read More

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December 2018
1 Read

Inflammatory demyelinating neuropathies with focal segmental glomerulosclerosis: Two case reports.

Medicine (Baltimore) 2018 Dec;97(49):e13304

Department of Nephrology, Huashan Hospital, Fudan University, Shanghai, China.

Rationale: Inflammatory demyelinating neuropathies such as Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and focal segmental glomerulosclerosis (FSGS) are autoimmune disorders that may have a common pathogenesis. Here, we describe 2 unique cases of FSGS, 1 with GBS and the other with CIPD. We believe that reviewing these multisystemic diseases will help in better understanding of FSGS pathogenesis. Read More

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December 2018

Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report.

Authors:

J Neurosurg 2018 Dec 1:1-7. Epub 2018 Dec 1.

The authors report on a 57-year-old woman in whom progression to brain death occurred on day 9 after aneurysmal subarachnoid hemorrhage without evidence of significant brain edema or vasospasm. Neuromonitoring demonstrated that brain death was preceded by a series of cortical spreading depolarizations that occurred in association with progressive hypoxic episodes. The depolarizations induced final electrical silence in the cortex and ended with a terminal depolarization that persisted > 7 hours. Read More

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December 2018

Volume-staged Gamma Knife radiosurgery for orbital venous malformations.

Authors:

J Neurosurg 2018 Dec;129(Suppl1):26-30

OBJECTIVEThis article is a preliminary evaluation of the efficacy of volume-staged Gamma Knife radiosurgery (GKRS) in the treatment of patients with orbital venous malformations (OVMs).METHODSTwenty patients with moderate to large OVMs were treated with volume-staged GKRS between March 2005 and October 2015. The series included 8 male and 12 female patients with an average age of 22. Read More

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December 2018

The Surgical Treatment of Adult Acquired Buried Penis Syndrome: A New Classification System.

Aesthet Surg J 2018 Dec 13. Epub 2018 Dec 13.

Departments of Surgery and Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Background: Adult acquired buried penis (AABP) syndrome may be associated with an inability to void, sexual dysfunction, and recurrent infection. Previously published classification systems rely on intraoperative findings, such as penile skin quality.

Objectives: The purpose of this study was to evaluate outcomes after AABP repair and to develop a classification system based on preoperative assessment. Read More

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December 2018
2 Reads

Field ultrasound evaluation of some gestational parameters in jennies.

Theriogenology 2018 Nov 22;126:95-105. Epub 2018 Nov 22.

Department of Veterinary Science, University of Torino, Largo Braccini 2/4, 10095, Grugliasco, TO, Italy.

The aim of this study was to collect and analyze ultrasound measurements of fetal-maternal structures during normal and pathological pregnancies in jennies, a livestock species of growing interest. For two breeding seasons, 38 jennies of different breeds and crossbreeds aged between 3 and 18 years were monitored weekly by transrectal examination using a portable Esaote ultrasound (MyLab™ 30 GOLD VET) with a 5-7.5 MHz probe. Read More

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November 2018

Comparison of different treatment schemes in 5-ALA interstitial photodynamic therapy for high-grade glioma in a preclinical model: An MRI study.

Photodiagnosis Photodyn Ther 2018 Dec 10. Epub 2018 Dec 10.

Univ. Lille, INSERM, CHU Lille, U1189, ONCO-THAI, Image-Assisted Laser Therapy for Oncology, F-59000, Lille, France; Department of Neurosurgery, University Hospital, F-59000, Lille, France.

Background: There is currently no therapy that prevents high-grade glioma recurrence. Thus, these primary brain tumors have unfavorable outcomes. Recently, 5-ALA photodynamic therapy (PDT) has been proposed to delay relapse and is highly expected to have potential synergistic effects with the current standard of care. Read More

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December 2018

Limitations of Cerebral Oximetry in a Patient With an Intracerebral Hemorrhage and Brain Edema on Extracorporeal Membrane Oxygenation: A Case Report.

A A Pract 2018 Dec 11. Epub 2018 Dec 11.

From the Division of Cardiothoracic and Vascular Anesthesia and Intensive Care Medicine, Department of Anesthesia, Intensive Care Medicine and Pain Medicine, General Hospital Vienna, Medical University of Vienna, Vienna, Austria.

Regional cerebral tissue saturation monitoring is frequently used in patients on mechanical cardiac assist devices with the intention to promptly detect critical imbalances between cerebral oxygen delivery and oxygen extraction and ultimately circumvent permanent brain injury. We report a case where an intraparenchymal bleed in the supply zone of the middle cerebral artery-followed by severe hemispherical brain edema, leading to life-threatening intracranial hypertension-escaped cerebral oximetry monitoring using near-infrared spectroscopy. Potential explanations for our observation, as well as the specific limitations of these devices, are discussed. Read More

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December 2018

Evaluation of the histopathological effects of salbutamol inhaler treatment in an experimentally induced rat model of pulmonary contusion

Turk J Med Sci 2018 12 12;48(6):1285-1292. Epub 2018 Dec 12.

Division of Pediatric Urology, Department of Pediatric Surgery, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey

Background/aim: This study aimed to evaluate the effects of salbutamol inhaler treatment in an experimentally induced model of pulmonary contusion.

Materials And Methods: Thirty-two male Wistar albino rats were randomly divided into four groups: the control group (CG), sham group (SG), treatment group 1 (TG1), and treatment group 2 (TG2). Experimental contusion was established by targeting the right lung tissue. Read More

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December 2018

Multiparametric Magnetic Resonance Imaging in the Assessment of Primary Brain Tumors Through Radiomic Features: A Metric for Guided Radiation Treatment Planning.

Cureus 2018 Oct 8;10(10):e3426. Epub 2018 Oct 8.

Radiation Oncology, University of Mississippi Medical Center, Jackson, USA.

Purpose The definition of radiotherapy target volume is a critical step in treatment planning for all tumor sites. Conventional magnetic resonance imaging (MRI) pulse sequences are used for the definition of the gross target volume (GTV) and the contouring of glioblastoma multiforme (GBM) and meningioma. We propose the use of multiparametric MRI combined with radiomic features to improve the texture-based differentiation of tumor from edema for GTV definition and to differentiate vasogenic from tumor cell infiltration edema. Read More

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October 2018

Immunosuppression-associated posterior reversible encephalopathy syndrome in an acute leukemia case.

Hematol Rep 2018 Nov 6;10(4):7257. Epub 2018 Nov 6.

Department of Hematology, Hacettepe University School of Medicine, Ankara, Turkey.

Posterior reversible encephalopathy syndrome (PRES) was described in 1996. Herein, we aimed to report an immunosuppression- related PRES case. A 34-year-old woman was diagnosed as t-cell acute lymphoblastic leukemia and allogeneic hematopoietic stem cell transplantation (HSCT) was performed. Read More

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November 2018

Prediction of brain invasion in patients with meningiomas using preoperative magnetic resonance imaging.

Oncotarget 2018 Nov 13;9(89):35974-35982. Epub 2018 Nov 13.

Department of Neurosurgery, University Hospital Münster, Münster, North Rhine-Westphalia, Germany.

Brain invasion (BI) in meningiomas impacts WHO grading and therefore adjuvant treatment. However, BI is rare and neurosurgical sampling and neuropathological analyses are not standardised. Moreover, associations with imaging findings are sparsely known. Read More

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November 2018

A case of incomplete Kawasaki disease with extremely high serum ferritin and interleukin-18 levels.

BMC Pediatr 2018 Dec 12;18(1):386. Epub 2018 Dec 12.

Department of Pediatrics and Child Health, Nihon University School of Medicine, 30-1, Oyaguchi, Kami-cho, Itabashi-ku, Tokyo, 173-8610, Japan.

Background: The clinical features and laboratory parameters of patients with Kawasaki disease (KD) and systemic juvenile idiopathic arthritis (sJIA) occasionally overlap. Therefore, serum levels of cytokine and ferritin are used as markers to distinguish between KD and sJIA. KD patients have a high level of interleukin (IL)-6, low level of IL-18, and no elevation of the level of serum ferritin. Read More

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December 2018

Combination of Intravitreal Corticosteroid with Anti-vegf in Macular Edema Secondary to Retinal Vein Occlusion.

Cesk Slov Oftalmol 2018 ;73(5-6):183-188

Purpose: functional and anatomical results after combination of intravitreal dexamethasone implant with anti-VEGF bevacizumab in macular edema secondary to retinal vein occlusion.

Methods: Retrospective analysis of 50 patients, average age 72 years, 15 men and 35 women. Inclusion criteria for treatment were retinal vein occlusion, best corrected visual acuity (BCVA) more than 20/200 and macular edema more than 250 μm. Read More

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January 2018

Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation.

J Ophthalmol 2018 4;2018:8463569. Epub 2018 Nov 4.

Ophthalmology Unit, University Hospital of Parma, Parma, Italy.

Purpose: To compare the functional and clinical outcomes of the iris-claw intraocular lens (IOL) placed on the anterior versus posterior surface of the iris.

Patients And Methods: A multicenter, retrospective study. Data on eyes that underwent anterior or retropupillary iris-claw IOL implantation because of inadequate capsular support secondary to complicated cataract surgery, trauma, and dislocated/opacified IOLs since January 2015 were analyzed. Read More

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November 2018

Lingual Abscess: Predisposing Factors, Pathophysiology, Clinical Manifestations, Diagnosis, and Management.

Int J Otolaryngol 2018 7;2018:4504270. Epub 2018 Nov 7.

Otolaryngology Unit, Phayao Hospital, Phayao, Thailand.

Lingual abscess is a rare disorder, and current knowledge regarding clinical manifestations and treatment modalities has not been well established. This study presented 6 cases of lingual abscess patients between January 2012 and December 2017. There were three men and three women. Read More

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November 2018

Baseline Gastrointestinal Eosinophilia Is Common in Oral Immunotherapy Subjects With IgE-Mediated Peanut Allergy.

Front Immunol 2018 22;9:2624. Epub 2018 Nov 22.

Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA, United States.

Oral immunotherapy (OIT) is an emerging treatment for food allergy. While desensitization is achieved in most subjects, many experience gastrointestinal symptoms and few develop eosinophilic gastrointestinal disease. It is unclear whether these subjects have subclinical gastrointestinal eosinophilia (GE) at baseline. Read More

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November 2018

Involvement of CYP2E1 in the Course of Brain Edema Induced by Subacute Poisoning With 1,2-Dichloroethane in Mice.

Front Pharmacol 2018 15;9:1317. Epub 2018 Nov 15.

Department of Environmental and Occupational Health, School of Public Health, China Medical University, Shenyang, China.

This study was designed to explore the role of cytochrome P4502E1 (CYP2E1) expression in the course of brain edema induced by subacute poisoning with 1,2-dichloroethane (1,2-DCE). Mice were randomly divided into five groups: the control group, the 1,2-DCE poisoned group, and the low-, medium- and high-dose diallyl sulfide (DAS) intervention groups. The present study found that CYP2E1 expression levels in the brains of the 1,2-DCE-poisoned group were upregulated transcriptionally; in contrast, the levels were suppressed by DAS pretreatment in the intervention groups. Read More

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November 2018

[Magnetic resonance imaging features for primary brain lymphoma].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Oct;43(10):1118-1122

Department of Diagnostic Radiology, Hunan Cancer Hospital, Changsha 410013, China.

Objective: To investigate the magnetic resonance imaging (MRI) features for primary brain lymphoma and improve its diagnosis and differential diagnosis.
 Methods: The clinical and MRI data from 14 patients with primary brain lymphoma were retrospectively reviewed.
 Results: Fourteen patients, including 5 males and 9 females, were (55±8) years old. Read More

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October 2018

Intraocular pressure change after injection of intravitreal dexamethasone (Ozurdex) implant in Korean patients.

Br J Ophthalmol 2018 Dec 6. Epub 2018 Dec 6.

Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea

Background/aims: To analyse intraocular pressure (IOP) changes over a period of 1 year after intravitreal dexamethasone (DEX, Ozurdex) implant injection and to compare the results with those of previously published studies that involved non-Asian populations.

Methods: A retrospective observational study was conducted. A total of 540 eyes of 503 patients who received DEX implant injection and were diagnosed with macular oedema (ME) due to various retinal diseases were examined. Read More

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December 2018

Retinopathy and RAAS Activation: Results From the Canadian Study of Longevity in Type 1 Diabetes.

Diabetes Care 2018 Dec 6. Epub 2018 Dec 6.

Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Objective: The importance of renin-angiotensin-aldosterone system (RAAS) activation in retinopathy for long-standing diabetes is not well understood. We determined retinopathy stage and evaluated associations with other vascular complications before and after physiological RAAS activation in adults with long-standing (≥50 years duration) type 1 diabetes.

Research Design And Methods: Participants underwent retinal examination by digital funduscopic photography and optical coherence tomography and were classified as having nonproliferative diabetic retinopathy (NPDR), proliferative diabetic retinopathy (PDR), or no diabetic retinopathy (NDR) with or without diabetic macular edema (DME). Read More

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December 2018
8.420 Impact Factor

Multimodal Imaging of the Initial Stages of Diabetic Retinopathy. Different Disease Pathways in Different Patients.

Diabetes 2018 Dec 6. Epub 2018 Dec 6.

AIBILI - Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal

To evaluate the prevalence of different disease pathways (ischemia, neurodegeneration and edema) in the initial stages of diabetic retinopathy (DR).In this retrospective cross-sectional study, eyes were grouped by DR severity using the 7-field ETDRS protocol (levels 10-20, 35 and 43-47). Neurodegeneration was identified by thinning of the retinal nerve fiber layer (RNFL) and/or ganglion cell layer (GCL). Read More

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December 2018

Venous perfusion assist system has no additional effect compared to simple elevation on post-operative edema in patients with distal radial fracture treated with volar locking plate fixation: A randomized controlled trial.

J Orthop Sci 2018 Dec 3. Epub 2018 Dec 3.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621, Japan.

Background: While limb elevation and other methods for reducing hand edema are commonly used in clinical practice, alternative methods, such as compression and venous perfusion assist system (VPAS), have emerged. This study compared the efficacy of VPAS to limb elevation in decreasing hand edema after surgery for distal radial fracture (DRF) treated by a volar locking plate (VLP).

Methods: A randomized controlled trial was conducted in 102 patients to compare VPAS and elevation methods for edema reduction following VLP fixation for DRF. Read More

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December 2018

Fulminant acute disseminated encephalomyelitis in children.

Brain Dev 2018 Dec 3. Epub 2018 Dec 3.

Department of Pediatrics, St Mary's Hospital, 422 Tsubukuhonmachi, Kurume, Fukuoka 830-8543, Japan; Research Centre for Children and Research Centre for Rett Syndrome, St Mary's Hospital, 422 Tsubukuhonmachi, Kurume, Fukuoka 830-8543, Japan. Electronic address:

Acute disseminated encephalomyelitis (ADEM) is a typically monophasic inflammatory demyelinating disease of the central nervous system with a favorable outcome. However, 2% of ADEM involves acute hemorrhagic leukoencephalitis (AHLE), which is a fulminant and hyperacute variant of ADEM with a poor outcome and high mortality. There are limited case reports of fulminant ADEM including AHLE in children. Read More

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December 2018

Cardiac Magnetic Resonance Fingerprinting: Technical Overview and Initial Results.

JACC Cardiovasc Imaging 2018 Dec;11(12):1837-1853

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio; Department of Cardiovascular Medicine, University Hospitals, Harrington Heart and Vascular Institute, Cleveland Medical Center and Case Western Reserve School of Medicine, Cleveland, Ohio; Department of Radiology, Case Western Reserve University, Cleveland, Ohio. Electronic address:

Cardiovascular magnetic resonance is a versatile tool that enables noninvasive characterization of cardiac tissue structure and function. Parametric mapping techniques have allowed unparalleled differentiation of pathophysiological differences in the myocardium such as the delineation of myocardial fibrosis, hemorrhage, and edema. These methods are increasingly used as part of a tool kit to characterize disease states such as cardiomyopathies and coronary artery disease more accurately. Read More

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December 2018

Effects of acidic and nonacidic reflux on the eustachian tube: An animal experiment.

Ear Nose Throat J 2018 Dec;97(12):E21-E27

MediENT Ear Nose and Throat Hospital, Halk Sokak no:50/1, Istanbul, Turkey.

We investigated the effects of pepsin/hydrochloric acid and bile acids on eustachian tube function and eustachian tube mucosa in 40 Sprague-Dawley rats. The animals were randomly assigned to groups of 10: one group received pepsin/hydrochloric acid (pepsin/HCl group), another received human bile (human bile group), a third received a mixture of pepsin/HCl and human bile (combination group), and the fourth received isotonic saline solution (control group). Test solutions were applied transnasally three times a day for 10 days. Read More

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December 2018
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