443 results match your criteria Hydronephrosis and Hydroureter


Complete Erosion of an Aortobifemoral Bypass Graft Limb into Duodenum.

Ann Vasc Surg 2020 Mar 20. Epub 2020 Mar 20.

Department of Vascular Surgery, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

A 67-year-old male with a history of aortobifemoral bypass graft (ABF) for critical limb ischemia 10 months prior at a regional hospital was transferred to our center with 1 week history of rigors and 3 months of a chronic discharging left groin sinus. Two months prior he had a right-sided ureteric stent inserted for ureteric obstruction. Routine bloods revealed an acute-on-chronic renal injury and subsequent noncontrast computed tomography (CT) demonstrated left-sided hydroureter and hydronephrosis suggestive of extrinsic compression by the left bypass graft limb. Read More

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http://dx.doi.org/10.1016/j.avsg.2020.02.029DOI Listing

Massive Bilateral Hydroureteronephrosis and End-Stage Renal Disease Ensuing From Chronic Schistosomiasis: A Case Report.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620910912

Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania.

Globally, schistosomal infections affect over 200 million people resulting in the loss of 70 million disability-adjusted life years. In the sub-Saharan Africa region, where over 85% of the global schistosomal infections are found, it is estimated that about 120 million people become symptomatic, over 20 million have severe disease, and nearly 200 000 die every year. Renal impairment is a severe consequence of schistosomiasis occurring in about 6% of all infected individuals and in 15% of those with the hepatosplenic form. Read More

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http://dx.doi.org/10.1177/2324709620910912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059228PMC

Ureteral Triplication- Laparoscopic Partial Nephrectomy With Highly Selective Arterial Dissection: Description of Surgical Technique.

Urology 2020 May 19;139:214. Epub 2020 Feb 19.

Department of Urology, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Background/objective: Ureteral triplication is a rare congenital malformation with a wide spectrum of presentation that requires a high index of suspicion in order to diagnose. To date, only about 100 cases have been published in medical literature. Smith et al proposed a classification for ureteral triplication that describes it as three separate ureters and three separate ureteral orifices with no interconnection between ureters. Read More

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http://dx.doi.org/10.1016/j.urology.2020.02.010DOI Listing

Cloacal Malformation in Female Children: Outcome of Initial Management.

Authors:
Naima Zamir

Pak J Med Sci 2020 Jan-Feb;36(2):187-191

Dr. Naima Zamir, Associate Professor, National Institute of Child Health, Karachi, Pakistan.

Objective: To document our experience of initial management of Cloacal malformation in female patients.

Methods: A descriptive retrospective study was conducted in the Department of Pediatric Surgery of the National Institute of Child Health Karachi from January 2010 to September 2018. Female patients with diagnosis of Cloacal malformation were included in this study. Read More

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http://dx.doi.org/10.12669/pjms.36.2.1095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994881PMC
February 2020

Congenital vaginal obstruction in a newborn.

Sudan J Paediatr 2019 ;19(2):145-148

Soba university Hospital, Khartoum, Sudan.

A transverse vaginal septum is a horizontal wall of tissue that has formed during embryologic development and essentially creates a blockage of the vagina. It can occur at different levels of the vagina. We report a neonate who was diagnosed antenatally with an enlarged lower abdominal mass suggestive of an enlarged urinary bladder with hydronephrosis and hydroureter. Read More

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http://dx.doi.org/10.24911/SJP.106-1543747330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962264PMC
January 2019

Gross Hematuria as a Presenting Feature of Posterior Urethral Valves in a Neonate with Normal Antenatal Sonograms.

Medicines (Basel) 2020 Jan 8;7(1). Epub 2020 Jan 8.

Department of Pediatrics, Division of Pediatric Nephrology, University of Florida, Gainesville, FL 32610, USA.

Posterior urethral valves (PUVs) are usually suspected during antenatal sonograms or by postnatal evidence of bilateral hydronephrosis with enlarged bladder. Gross hematuria as an initial manifestation of PUV with a history of normal antenatal sonogram is very rare. This is a retrospective chart study. Read More

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http://dx.doi.org/10.3390/medicines7010005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168229PMC
January 2020

Retrocaval ureter: a rare cause of intermittent right flank pain in a 37 years old lady.

Authors:
Shoaib Rafique

J Pak Med Assoc 2019 Nov;69(11):1734-1736

Bakhtawar Amin Trust Teaching Hospital, Multan, Punjab.

A 37 years old female presented with 6 months history of intermittent right flank pain. She was otherwise fit and had no other complaints. Her lab investigations were normal. Read More

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http://dx.doi.org/10.5455/JPMA.3081.DOI Listing
November 2019

A Cadaveric Report on a Giant Ureteric Stone Led Right Hydro Ureter and Severe Hydronephrosis.

Ethiop J Health Sci 2019 Sep;29(5):649-652

Department of Anatomy, Kasturba Medical College Manipal, Manipal Academy of Higher Education.

Background: The ureter shows natural constrictions in its course, and these are the potential site for the impaction of the renal calculus. Giant ureteral stones are associated with insidious growth and late presentation, often leading to renal failure.

Case Presentation: In the present case, we observed a huge ureteric stone obstructing the right ureterovesical junction in a 58 year-old male cadaver. Read More

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http://dx.doi.org/10.4314/ejhs.v29i5.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813267PMC
September 2019
1 Read

Does the presence of non-refluxing hydroureter impact the management and outcome of high-grade hydronephrosis?

Can Urol Assoc J 2020 Mar 27;14(3):E94-E100. Epub 2019 Sep 27.

Department Pediatric Surgery, Montreal Children's Hospital, McGill University, Montreal, QC, Canada.

Introduction: We aimed to evaluate the impact of non-refluxing hydroureter on the initial management of high-grade hydronephrosis (HGH) management. Moreover, we evaluated the occurrence of febrile urinary tract infection (fUTI) and surgical intervention for conservatively managed units.

Methods: Patients' charts with postnatal hydronephrosis from 2008-2014 were retrospectively reviewed. Read More

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http://dx.doi.org/10.5489/cuaj.6080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053371PMC
March 2020
1 Read

Urogenital tuberculosis - epidemiology, pathogenesis and clinical features.

Nat Rev Urol 2019 10 23;16(10):573-598. Epub 2019 Sep 23.

Department of Clinical Microbiology, University College London Hospitals NHS Foundation Trust, London, UK.

Tuberculosis (TB) is the most common cause of death from infectious disease worldwide. A substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG-TB), which can easily be overlooked owing to non-specific symptoms, chronic and cryptic protean clinical manifestations, and lack of clinician awareness of the possibility of TB. Delay in diagnosis results in disease progression, irreversible tissue and organ damage and chronic renal failure. Read More

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http://dx.doi.org/10.1038/s41585-019-0228-9DOI Listing
October 2019
3 Reads

Bilateral hydronephrosis and hydroureter associated with 21-22 weeks gestational age of cervical ectopic pregnancy: a case report.

Int Med Case Rep J 2019 11;12:217-222. Epub 2019 Jul 11.

Division of Reproductive, Endocrinology and Infertility, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Cervical ectopic pregnancy is a rare form of ectopic pregnancy. This incidence represents less than 1% of all ectopic pregnancies with reported incidence rates varying from 1:1,000 to 1:95,000 pregnancies. Cervical ectopic pregnancy is difficult to diagnose. Read More

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http://dx.doi.org/10.2147/IMCRJ.S199683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630720PMC
July 2019
3 Reads

Primary Non-refluxing Megaureter: Analysis of Risk Factors for Spontaneous Resolution and Surgical Intervention.

Front Pediatr 2019 9;7:126. Epub 2019 Apr 9.

McMaster Pediatric Surgery Research Collaborative, McMaster University, Hamilton, ON, Canada.

The risk of febrile urinary tract infection (fUTI) in children with primary non-refluxing megaureter (PM) has been extensively studied in the literature, however, a paucity of information exists regarding risk factors for surgical intervention and spontaneous resolution. We sought to analyze data from our prospectively collected PM cohort to determine risk factors that would predict surgery and resolution in this population. Patients with PM were identified from our prospectively-collected prenatal hydronephrosis (HN) database from 2008 to 2017. Read More

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https://www.frontiersin.org/article/10.3389/fped.2019.00126/
Publisher Site
http://dx.doi.org/10.3389/fped.2019.00126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499225PMC
April 2019
5 Reads

Homozygous noncanonical splice variant in in two siblings with multiple congenital anomalies and global developmental delay.

Cold Spring Harb Mol Case Stud 2019 06 3;5(3). Epub 2019 Jun 3.

Department of Pediatrics, Columbia University, New York, New York 10032, USA.

Two siblings, one male and one female, ages 6 and 13 yr old, have similar clinical features of global developmental delay, multiple congenital anomalies affecting the cardiac, genitourinary, and skeletal systems, and abnormal eye movements. Whole-genome sequencing revealed a homozygous splice variant (NM_014462.3:c. Read More

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http://dx.doi.org/10.1101/mcs.a004101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549555PMC
June 2019
12 Reads

Diuresis renography in the evaluation and management of pediatric hydronephrosis: What have we learned?

J Pediatr Urol 2019 Apr 28;15(2):128-137. Epub 2019 Jan 28.

Division of Pediatric Urology, Children's National Health System, Washington, DC, USA. Electronic address:

Diuresis renography (DR) is widely used in the evaluation of hydronephrosis and hydroureter in infants and children. The goal of this provocative nuclear imaging examination should be to detect the hydronephrotic kidneys at risk for loss of function and development of pain, hematuria, and urinary tract infection. The reliability of DR is dependent on the acquisition and processing of the data as well as interpretation and utilization of the results. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14775131183061
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http://dx.doi.org/10.1016/j.jpurol.2019.01.011DOI Listing
April 2019
11 Reads

Endovascular Repair of Inflammatory Aortic Aneurysms: Experience in a Single Center.

Ann Vasc Surg 2019 Jul 6;58:255-260. Epub 2019 Feb 6.

Department of General, Vascular and Thoracic Surgery, Centre Hospitalière Regional du Val de Sambre Rue Chère-Voie, Sambreville, Belgium.

Background: Inflammatory abdominal aortic aneurysm (IAAA) remained a rare cause of aneurysmal aortic disease, with incidences between 5% and 10%. The current treatment for IAAA consists of open surgical repair and endovascular aneurysm repair (EVAR). Avoiding an inflamed, fibrotic retroperitoneum is the driving force behind the desire to repair IAAA endovascularly. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.10.046DOI Listing
July 2019
41 Reads

Urinary tract anomalies and urinary tract dysfunction in children with Hirschsprung disease-Is follow-up indicated?

J Pediatr Surg 2019 Oct 27;54(10):2012-2016. Epub 2018 Dec 27.

Department of Pediatric surgery, Skane University Hospital Lund, Institution of Clinical Sciences, Department of Pediatrics, 221 85 Lund, Sweden.

Background/purpose: Urinary tract function in children with Hirschsprung disease (HD) is rarely considered.

Aim: to evaluate the prevalence of urinary tract anomalies and dysfunction in children with HD compared to controls.

Methods: This was an observational cross sectional case-control study. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.12.006DOI Listing
October 2019
8 Reads

Unusual bilateral ureter strangulation by fibrous tissue after perineal hernia repair in a dog.

Open Vet J 2018 19;8(4):441-444. Epub 2018 Nov 19.

Hokkaido University Veterinary Teaching Hospital, Kita 19, Nishi 10, Kita-ku, Sapporo, Hokkaido 060-0819, Japan.

A 10-year-old castrated male cross-breed dog was referred for the repair of perineal hernia with bladder retroflexion and a mass lesion in the hernial sac. Surgical treatment was performed and the mass was identified as degenerated adipose tissue that was suspected to be derived from the omentum. The hernial contents were reduced without difficulty, and the dog exhibited a normal recovery. Read More

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http://dx.doi.org/10.4314/ovj.v8i4.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258517PMC
November 2018
6 Reads

Subcutaneous ureteral bypass for treatment of bilateral ureteral obstruction in a cat with retroperitoneal paraganglioma.

J Am Vet Med Assoc 2018 Nov;253(9):1169-1176

CASE DESCRIPTION A 7-year-old female domestic shorthair cat was referred for evaluation of azotemia and unilateral hydronephrosis. CLINICAL FINDINGS Abdominal ultrasonography revealed right-sided hydronephrosis and dilation of the proximal aspect of the ureter; the left kidney was small with irregular margins. A highly vascular, irregular retroperitoneal mass, not clearly associated with the ureteral obstruction, was also visualized. Read More

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https://avmajournals.avma.org/doi/10.2460/javma.253.9.1169
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http://dx.doi.org/10.2460/javma.253.9.1169DOI Listing
November 2018
11 Reads

Acute synchronous appendicitis and obstructing ureterolithiasis.

Radiol Case Rep 2018 Oct 3;13(5):952-954. Epub 2018 Aug 3.

Icahn School of Medicine at Mount Sinai, Mount Sinai Services - Queens Hospital Center, Department of Radiology, Queens, NY 11432, USA.

This is an unusual case of a patient presenting to the Emergency Room with right-sided abdominal pain and subsequently 2 acute diagnoses were made. The patient had both acute appendicitis and acute ureterolithiasis. Read More

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http://dx.doi.org/10.1016/j.radcr.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083375PMC
October 2018
14 Reads

Clinical characteristics of lupus enteritis in Japanese patients: the large intestine-dominant type has features of intestinal pseudo-obstruction.

Lupus 2018 Sep 20;27(10):1661-1669. Epub 2018 Jul 20.

Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.

This study was performed to investigate the clinical characteristics of lupus enteritis in Japanese patients with systemic lupus erythematosus (SLE). A total of 481 patients with SLE admitted to our hospital between 2001 and 2015 were retrospectively reviewed. Diagnosis of lupus enteritis was based on the following three criteria: (1) abdominal symptoms, (2) diffuse long-segment bowel thickening and (3) a requirement for glucocorticoid therapy. Read More

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http://dx.doi.org/10.1177/0961203318785770DOI Listing
September 2018
48 Reads

Bladder metastasis from primary breast cancer: a case report.

Surg Case Rep 2018 Jul 9;4(1):73. Epub 2018 Jul 9.

Department of Breast Surgery, Hiratsuka City Hospital, 1-19-1 Minamihara, Hiratsuka-shi, Kanagawa, 254-0065, Japan.

Background: Breast cancer frequently metastasizes to the bone, lung, and liver. However, metastasis to the bladder is uncommon. Bladder metastasis due to direct infiltration from peripheral organs, such as the colon and rectum, prostate, and cervix, occurs more frequently than metastasis from distant organs, such as the breast. Read More

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https://surgicalcasereports.springeropen.com/articles/10.118
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http://dx.doi.org/10.1186/s40792-018-0484-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037656PMC
July 2018
50 Reads

Evaluating Neonates With Antenatal Hyderonephrosis Using a Standard Protocol: An Audit of Hospital Records.

Indian Pediatr 2018 Nov 2;55(11):966-968. Epub 2018 Jun 2.

Department of Radiology, Sri Ramachandra University, Porur, Chennai, India.

Aims: To audit the extent of evaluation of neonates with antenatal hydronephrosis.

Methods: Records of all neonates with antenatal hydronephrosis between January 2013 and December 2016 were audited to look for patient factors and investigation results.

Results: 290 records were evaluated, 93 (32%) of which had abnormalities detected on voiding cystourethrogram. Read More

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November 2018
30 Reads

Use of radiography, ultrasonography, and computed tomography in the diagnosis of a pyogranulomatous ureteral mass in a cat.

Vet Radiol Ultrasound 2018 Jun 25. Epub 2018 Jun 25.

Veterinary Specialty Hospital of the Carolinas, Cary, NC, 27518.

An 8-year-old, spayed female, domestic short haired cat, with diabetes mellitus, was presented to the University of Florida Veterinary Medical Center for an acute onset of vomiting and inappetence. Abdominal radiographs showed mild retroperitoneal effusion and asymmetric left-sided renomegaly. Subsequently, on abdominal ultrasound, a hypoechoic left ureteral mass with left hydronephrosis and hydroureter was identified. Read More

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http://doi.wiley.com/10.1111/vru.12660
Publisher Site
http://dx.doi.org/10.1111/vru.12660DOI Listing
June 2018
16 Reads
1.453 Impact Factor

Influence of postnatal hydroureter in determining the need for voiding cystourethrogram in children with high-grade hydronephrosis.

Arab J Urol 2018 Jun 13;16(2):238-244. Epub 2017 Dec 13.

Departments of Surgery and Pediatric Surgery, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada.

Objective: To evaluate the utility of hydroureter (HU) to identify high-grade vesico-ureteric reflux (VUR) in patients with high-grade postnatal hydronephrosis (PH).

Patients And Methods: We retrospectively reviewed patients' charts that had antenatal hydronephrosis from 2008 to 2014. Patients were excluded if they presented with febrile urinary tract infection (fUTI), neurogenic bladder, posterior urethral valve, multi-cystic dysplastic kidney, and multiple congenital malformations. Read More

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http://dx.doi.org/10.1016/j.aju.2017.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992681PMC
June 2018
36 Reads

Late presentation of ectopia vesica with malignant transformation. A case report and review.

Int J Surg Case Rep 2018 10;48:43-46. Epub 2018 May 10.

Ibrahim Malik Hospital, Sudan.

Introduction: Exstrophy of the bladder is a rare congenital anomaly usually treated in neonatal or childhood period. When combined with renal agenesis and presents for the first time in the adulthood with malignant transformation, is an extreme rarity.

Case Presentation: We present a case of 65 years single male who presented with a right irreducible inguinal hernia and an unreconstructed Ectopia Vesicae with fungating tumor. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.04.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028663PMC
May 2018
29 Reads

Active surveillance for antenatally detected ureteroceles: Predictors of success.

J Pediatr Urol 2018 06 13;14(3):243.e1-243.e6. Epub 2018 Mar 13.

Division of Urology, Department of Surgery, Children's Hospital of Eastern Ontario, Ottawa, Canada; Faculty of Medicine, University of Ottawa, Ottawa, Canada; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Canada. Electronic address:

Introduction: Historically, ureteroceles were surgically treated, as patients were diagnosed after developing symptoms. However, with the advance of fetal medicine, antenatal detection has provided an opportunity to look at the natural history of ureteroceles.

Objectives: With data derived from a retrospective chart review of patients with ureteroceles that were detected antenatally, the current study aimed to determine which group of children would be at risk for failure on active surveillance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14775131183009
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http://dx.doi.org/10.1016/j.jpurol.2018.02.012DOI Listing
June 2018
20 Reads

Encrusted Cystitis with Suspected Ureteral Obstruction Following Cystoscopic-Guided Laser Ablation of Ectopic Ureters in a Dog.

J Am Anim Hosp Assoc 2018 Mar/Apr;54(2):117-123. Epub 2018 Jan 26.

From the Small Animal Hospital, College of Veterinary Medicine, University of Florida, Gainesville, Florida.

A 1 yr old 30 kg spayed female Labrador retriever presented for stranguria and hematuria 3 wk after cystoscopic laser ablation for ectopic ureters. Encrusted cystitis was diagnosed based on ultrasonography, cystoscopy, urinalysis, and culture of Corynebacterium urealyticum from the urine. Unilateral hydronephrosis and hydroureter were suspected to be secondary to obstruction at the trigone. Read More

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http://dx.doi.org/10.5326/JAAHA-MS-6392DOI Listing
January 2019
5 Reads

Nephrotic syndrome in primary myelofibrosis with renal extramedullary hematopoiesis and glomerulopathy in the JAK inhibitor era.

Clin Nephrol Case Stud 2017 24;5:70-77. Epub 2017 Jul 24.

Department of Experimental Medicine-Section of Pathological Anatomy and Histology, Medical School, University of Perugia.

Primary myelofibrosis (PMF) is an uncommon form of myeloproliferative neoplasm (MPN) characterized by a proliferation of predominantly megakaryocytes and granulocytes in the bone marrow that, in fully-developed disease, is associated with reactive deposition of fibrous connective tissue, extramedullary hematopoiesis (EMH), and splenomegaly. Kidney involvement is rare and clinically presents with proteinuria, nephrotic syndrome, and renal insufficiency. Renal damage can be due to EMH and glomerulopathy. Read More

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http://dx.doi.org/10.5414/CNCS109100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715205PMC
July 2017
23 Reads

Ureteric entrapment in sacroiliac joint causing hydroureter and ipsilateral kidney hypertrophy.

Anat Sci Int 2018 Jun 8;93(3):394-399. Epub 2017 Dec 8.

Department of Anatomy, Dokkyo Medical University, Mibu, Tochigi, 321-0293, Japan.

A unilateral megaureter was found in an elderly female cadaver during routine dissection. The left proximal ureter, which was thick and convolute, descended and entered into the pelvic cavity, where the distal ureter was attached to the posterior pelvic wall at the inlet level. Removal of connective tissue surrounding the attached region revealed ureteric entrapment in the sacroiliac joint. Read More

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http://dx.doi.org/10.1007/s12565-017-0425-7DOI Listing
June 2018
13 Reads

Prune belly syndrome: A report of 15 cases from Sudan.

Sudan J Paediatr 2017 ;17(1):42-48

Department of Paediatrics, Soba university hospital, Khartoum, Sudan.

Prune belly syndrome is a rare congenital malformation of unknown aetiology, composed of a triad of deficient abdominal wall muscle, cryptorchidism and urinary tract anomalies. The majority of patients have associated pulmonary, skeletal, cardiac, and gastrointestinal defects. This was a prospective, case finding study that was conducted in the main paediatric hospitals in Khartoum state, during the period December 2015 to September 2016. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621858PMC
January 2017
25 Reads

Transurethral incision of ureteroceles in paediatric age group.

Turk J Urol 2017 Dec 1;43(4):530-535. Epub 2017 Dec 1.

TNMC & BYL Nair Hospital, Mumbai, Maharashtra, India.

Objective: Ureteroceles are a great clinical challenge because of variations in anatomy and clinical presentations. We present our experience with primary transurethral incision of ureteroceles in children.

Material And Methods: Data of thirteen children managed for ureterocele from 2009 to 2016 was retrospectively analyzed with respect to age, sex, clinical presentation and symptomatology, type and localization of ureterocele, investigations, surgical management and follow-up. Read More

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http://turkishjournalofurology.com/eng/makale/3126/168/Full-
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http://dx.doi.org/10.5152/tud.2017.57514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687220PMC
December 2017
160 Reads

Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10 and Wnt5a.

Hum Mol Genet 2018 01;27(1):107-119

Department of Orofacial Sciences, University of California, San Francisco, CA 94143, USA.

Genital malformations are among the most common human birth defects, and both genetic and environmental factors can contribute to these malformations. Development of the external genitalia in mammals relies on complex signaling networks, and disruption of these signaling pathways can lead to genital defects. Islet-1 (ISL1), a member of the LIM/Homeobox family of transcription factors, has been identified as a major susceptibility gene for classic bladder exstrophy in humans, a common form of the bladder exstrophy-epispadias complex (BEEC), and is implicated in a role in urinary tract development. Read More

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http://dx.doi.org/10.1093/hmg/ddx388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886284PMC
January 2018
36 Reads

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection.

Authors:
Kangsun Yun

J Vis Exp 2017 10 12(128). Epub 2017 Oct 12.

Cancer and Developmental Biology Laboratory, National Cancer Institute, National Institutes of Health;

Urinary tract junction obstruction defects are congenital anomalies inducing hydronephrosis and hydroureter. Murine urinary tract junction obstruction defects can be assessed by tracking methylene blue dye flow within the urinary system. Methylene blue dye is injected into the renal pelvis of perinatal embryonic kidneys and dye flow is monitored from the renal pelvis of the kidney through the ureter and into the bladder lumen after applying hydrostatic pressure. Read More

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http://dx.doi.org/10.3791/56247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752404PMC
October 2017
32 Reads

Predictive value of secondary signs of obstruction in follow-up computed tomography of ureteral stones: a study with dynamic computed tomography.

Scand J Urol 2018 Feb 16;52(1):59-64. Epub 2017 Oct 16.

a Department of Surgical Sciences, Section of Radiology , Uppsala University Hospital , Uppsala , Sweden.

Objectives: This study aimed to determine the ratio of obstruction and predictive values of secondary signs in follow-up computed tomography (CT) of ureterolithiasis patients; to correlate stone characteristics with obstruction; to compare enhancement of obstructed and non-obstructed kidneys; and to compare radiation dose of the dynamic CT protocol to an excretory-phase protocol.

Materials And Methods: This retrospective study assessed 49 follow-up CT scans of patients with remaining ureterolithiasis after a renal colic episode. Obstruction was measured as time taken to excretion of contrast medium in dynamic CT. Read More

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http://dx.doi.org/10.1080/21681805.2017.1386232DOI Listing
February 2018
17 Reads

Extrarenal pelvis mimicking hydronephrosis: a case for caution.

Clin Case Rep 2017 10 24;5(10):1720-1721. Epub 2017 Aug 24.

Division of Nephrology, Hypertension and Renal Transplantation University of Florida Gainesville Florida.

Extrarenal pelvis is an anatomical variant that appears as a large hypoechoic mass just outside the renal sinus and can be confused with hydronephrosis, especially on a point-of-care renal ultrasound. Unlike hydronephrosis, it is not associated with dilated calyces, parenchymal thinning, hydroureter, or enlarged kidney per se. Read More

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http://dx.doi.org/10.1002/ccr3.1143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628238PMC
October 2017
21 Reads

Ureter metastatic castration-resistant prostate cancer: a case report.

J Med Case Rep 2017 Sep 6;11(1):215. Epub 2017 Sep 6.

Departments of Urology and Renal Transplantation, Yokohama City University Medical Center, Yokohama, Japan.

Background: In most cases, prostate cancer metastasizes to the lymph nodes, bone, and liver. In very rare cases, it metastasizes to the ureter. Due to the difficulty in making a preoperative diagnosis, ureteral metastasis from prostate cancer is typically diagnosed after nephroureterectomy. Read More

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http://dx.doi.org/10.1186/s13256-017-1379-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585961PMC
September 2017
24 Reads

Multimodality imaging of primary ureteral hemangiosarcoma with thoracic metastasis in an adult dog.

Vet Radiol Ultrasound 2019 Jul 27;60(4):E38-E41. Epub 2017 Jul 27.

North Downs Specialist Referrals, Bletchingley, United Kingdom of Great Britain and Northern Ireland.

A 12-year-old spayed female standard Poodle was presented for investigation of severe hematuria. Abdominal ultrasound and thoracic and abdominal computed tomography identified severe hydronephrosis due to an obstructive ureteral mass with no evidence of metastasis. Histological examination after nephrectomy and ureterectomy confirmed an obstructive ureteral hemangiosarcoma. Read More

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http://doi.wiley.com/10.1111/vru.12537
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http://dx.doi.org/10.1111/vru.12537DOI Listing
July 2019
67 Reads

MYCOBACTERIUM INTRACELLULARE INFECTION CAUSING A RETROPERITONEAL MASS IN A BINTURONG (ARCTICTIS BINTURONG).

J Zoo Wildl Med 2017 Jun;48(2):544-548

A 19-yr-old castrated male binturong ( Arctictis binturong ) with a history of recurrent pyogranulomatous panniculitis, lymphangitis, and dermatitis was presented for evaluation of hyporexia and tenesmus. A large caudal abdominal mass was palpated on physical examination. On ultrasound, the mass encircled and obstructed the left ureter, resulting in hydroureter and hydronephrosis. Read More

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http://dx.doi.org/10.1638/2016-0117R.1DOI Listing
June 2017
30 Reads

Computed tomographic characteristics for patients with unresectable gastric cancer harboring low-volume peritoneal carcinomatosis.

Med Oncol 2017 Aug 19;34(8):143. Epub 2017 Jul 19.

Department of Oncology, National Taiwan University Hospital, Taipei City, Taiwan.

Although current staging workups could differentiate most patients with operable from inoperable advanced gastric cancers, there are still some patients with low-volume peritoneal carcinomatosis, defined as only metastasis with multiple subcentimeter lesions in peritoneum, receiving unnecessary open-close procedures. The computed tomography (CT) of the patients with unresectable advanced gastric cancer harboring low-volume peritoneal carcinomatosis was retrospectively identified and then thoroughly reviewed by two independent radiologists unaware of the peritoneal carcinomatosis status. Of the 798 patients with newly diagnosed gastric cancer between January 2007 and December 2010, 52 patients harboring advanced gastric cancer with low-volume peritoneal carcinomatosis receiving surgery with curative intent were identified. Read More

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http://dx.doi.org/10.1007/s12032-017-1004-4DOI Listing
August 2017
18 Reads

BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter.

Hum Mol Genet 2017 09;26(18):3553-3563

Institut für Molekularbiologie, OE5250, Medizinische Hochschule Hannover, 30625 Hannover, Germany.

Heterozygous loss of Bmp4 results both in humans and mice in severe malformation of the urinary tract. These defects have at least partially been attributed to loss of expression of Bmp4 in the ureteric mesenchyme, yet the cellular and molecular function of this signal as well as its effector pathways in this tissue have remained incompletely resolved. Here, we show that mice with a conditional deletion of Bmp4 in the ureteric mesenchyme exhibited hydroureter and hydronephrosis at newborn stages due to functional and physical ureter obstruction. Read More

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http://dx.doi.org/10.1093/hmg/ddx242DOI Listing
September 2017
38 Reads

Resolution of nonurine transudative pleural effusion in a cat after removal of a hydronephrotic kidney.

J Am Vet Med Assoc 2017 Jul;251(1):80-83

CASE DESCRIPTION A 3-year-old spayed female Bengal cat was evaluated because of a history of bilateral pleural effusion and hydronephrosis of the right kidney. CLINICAL FINDINGS Cytologic analysis of a pleural fluid sample revealed characteristics of a pure transudate with a high percentage of lymphocytes. Results of fluid biochemical testing were not consistent with urine or chyle. Read More

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http://dx.doi.org/10.2460/javma.251.1.80DOI Listing
July 2017
24 Reads

[Spontaneous renal rupture of fornix due to obstructing urethral stone].

Ugeskr Laeger 2017 Jun;179(24)

A 53-year-old man was hospitalized due to acute right-sided flank pain. The pain went from right flank to right fossa. A non-contrast computed tomography (CT) of the abdomen showed pronounced stranding, hydronephrosis and proximal hydroureter. Read More

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June 2017
22 Reads

Computed tomographic features of urinary bladder torsion in two dogs.

J Small Anim Pract 2018 03 9;59(3):188-195. Epub 2017 Jun 9.

Pingry Veterinary Hospital, via Medaglie d'Oro 5, Bari, 70126, Italy.

Urinary bladder torsion is rare in dogs. It is characterised by rotation of the organ along its longitudinal axis and is potentially life-threatening because of urinary flow obstruction with subsequent urine retention, hydroureter, hydronephrosis and azotaemia. This report describes the computed tomographic features of urinary bladder torsion in two dogs. Read More

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http://dx.doi.org/10.1111/jsap.12694DOI Listing
March 2018
35 Reads

Constitutive Activation of Smoothened in the Renal Collecting Ducts Leads to Renal Hypoplasia, Hydronephrosis, and Hydroureter.

Cells Tissues Organs 2017 1;204(1):38-48. Epub 2017 Jun 1.

Department of Anatomy, Chonbuk National University Medical School and Institute for Medical Sciences, Chonbuk National University, Jeonju, Republic of Korea.

Sonic Hedgehog (Shh) signaling plays a major role in and is essential for regulation, patterning, and proliferation during renal development. Smoothened (Smo) plays a pivot role in transducing the Shh-glioma-associated oncogene Kruppel family member. However, the cellular and molecular mechanism underlying the role of sustained Smo activation in postnatal kidney development is still not clearly understood. Read More

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http://dx.doi.org/10.1159/000464460DOI Listing
March 2018
29 Reads

Evaluation of the Effect of Meatal Stenosis on the Urinary Tract by using Ultrasonography.

Urol J 2017 May 23;14(3):3071-3074. Epub 2017 May 23.

Assistant professor of Urology, Mashhad University of Medical Science, Mashhad, Iran.

Purpose: Circumcision is one of the oldest surgical procedures that originated for religious purposes. Circumcision in infancy is a common procedure in our country and secondary meatal stenosis due to circumcision is a common complication. The aim of our study is to determine the effect of meatal stenosis on the lower and upperurinary tract of circumcised boys by using ultrasonography. Read More

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May 2017
37 Reads

Novel de novo variant in is likely to impact DNA binding in a patient with a neurodevelopmental disorder and expanded phenotypes: patient report, in silico functional assessment, and review of published cases.

Cold Spring Harb Mol Case Stud 2017 05;3(3):a001743

Department of Clinical Genomics, Mayo Clinic, Rochester, Minnesota 55905, USA.

Pathogenic variants in were recently described in three back-to-back publications in association with a novel neurodevelopmental disorder characterized by intellectual disability, speech delay, ataxia, and facial dysmorphisms. In this report, we describe an additional patient carrying a de novo missense variant in (c.487C>T, p. Read More

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http://molecularcasestudies.cshlp.org/lookup/doi/10.1101/mcs
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http://dx.doi.org/10.1101/mcs.a001743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411688PMC
May 2017
89 Reads

Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia.

Dev Biol 2017 07 3;427(1):121-130. Epub 2017 May 3.

Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan. Electronic address:

In kidney development, connection of the nephric duct (ND) to the cloaca and subsequent sprouting of the ureteric bud (UB) from the ND are important for urinary exit tract formation. Although the roles of Ret signaling are well established, it remains unclear how intracellular cytoskeletal proteins regulate these morphogenetic processes. Myh9 and Myh10 encode two different non-muscle myosin II heavy chains, and Myh9 mutations in humans are implicated in congenital kidney diseases. Read More

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http://dx.doi.org/10.1016/j.ydbio.2017.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447305PMC
July 2017
34 Reads

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.

Hum Mol Genet 2017 05;26(9):1716-1731

Department of Human Genetics.

Congenital anomalies of the kidneys and urinary tract (CAKUT) are the most common cause of chronic kidney disease in children. As CAKUT is a genetically heterogeneous disorder and most cases are genetically unexplained, we aimed to identify new CAKUT causing genes. Using whole-exome sequencing and trio-based de novo analysis, we identified a novel heterozygous de novo frameshift variant in the leukemia inhibitory factor receptor (LIFR) gene causing instability of the mRNA in a patient presenting with bilateral CAKUT and requiring kidney transplantation at one year of age. Read More

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http://dx.doi.org/10.1093/hmg/ddx086DOI Listing
May 2017
71 Reads