372 results match your criteria Hydrofluoric Acid Burns


Dermal Hydrofluoric Acid Toxicity Case Review: Looks Can Be Deceiving.

J Emerg Nurs 2021 Jan 9;47(1):28-32. Epub 2020 Nov 9.

Hydrofluoric acid is a caustic compound found in a wide variety of items for household and industrial uses. Dermal exposures can be visually unimpressive on presentation but still have fatal complications. This case review includes a description of a patient presenting with a dermal hydrofluoric acid burn that was effectively treated with topical calcium gluconate gel. Read More

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January 2021

[Research advances on the diagnosis and treatment of hydrofluoric acid inhalation injury].

Zhonghua Shao Shang Za Zhi 2020 Oct;36(10):975-978

Department of Burns, Gansu Provincial Hospital, Lanzhou 730000, China.

Hydrofluoric acid inhalation injury is difficult to treat, despite it has low incidence. It could cause mild symptoms such as cough and sore throat, or severe symptom that may develop into life-threatening acute respiratory distress syndrome, and even rare pulmonary diseases such as reactive airway dysfunction syndrome and pulmonary alveolar proteinosis. Currently, there is no specific standard for the diagnosis and treatment of hydrofluoric acid inhalation injury. Read More

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October 2020

Management of Hydrofluoric Acid Burns in the Emergency Department.

Cureus 2020 Mar 1;12(3):e7152. Epub 2020 Mar 1.

Emergency Medicine, Envision Physician Services, Orlando, USA.

Hydrofluoric acid burns are uncommon but unique among chemical burns in that they can cause visually mild burns with significant deep tissue injury and systemic toxicity through multiple mechanisms. We present the case of a patient who presented with bilateral hydrofluoric acid burns to his hands from aluminum brightener. The patient had been using an aluminum brightener with a hydrofluoric acid concentration of 10% for several months at work. Read More

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Application of calcium nebulization for mass exposure to an accidental hydrofluoric acid spill.

Burns 2020 09 21;46(6):1337-1346. Epub 2020 Mar 21.

Department of Emergency Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. Electronic address:

Purpose: To determine the long-term prevalence and characteristics of acute hydrofluoric acid (HF) exposure in 2223 patients during the first 30 months after a mass-casualty exposure, and to confirm the antidotal effect of nebulized calcium on inhalation burns caused by HF.

Methods: This observational cohort study included patients after an HF spill in the Republic of Korea on September 27, 2012; registered patients were followed until April 2015. We assessed toxic effects, distance from spill, degree of acute poisoning, and the effect of nebulized calcium in HF-exposed individuals. Read More

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September 2020

Potentially fatal electrolyte imbalance caused by severe hydrofluoric acid burns combined with inhalation injury: A case report.

World J Clin Cases 2019 Oct;7(20):3341-3346

Department of Burn and Plastic Surgery, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou 215002, Jiangsu Province, China.

Background: Hydrofluoric acid (HF) is one of the most common causes of chemical burns. HF burns can cause wounds that deepen and progress aggressively. As a result, HF burns are often severe even if they involve a small area of the skin. Read More

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October 2019

Hybrid Uranyl-Phosphonate Coordination Nanocage.

Inorg Chem 2019 Oct 12;58(19):12662-12668. Epub 2019 Sep 12.

Department of Chemistry and Biochemistry , St. Mary's University , San Antonio , Texas 78228 , United States.

We report herein a general synthetic approach for designing uranyl coordination cages. Compounds and are constructed through a temperature-dependent and solvent-driven self-assembly. In both cases, the synthetic strategy involves in situ phosphonate ligand condensation into a flexible pyrophosphonate ligand. Read More

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October 2019

Management of a Man With Hydrofluoric Acid Burns: A Case Report and Review.

J Burn Care Res 2020 01;41(1):200-210

Department of Burn and Plastic Surgery, Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, China.

A hydrofluoric acid (HFA) burn is a severe condition with the characteristics of acute onset, rapid progression, and high complication and mortality rates. Emergency and systemic treatments are especially important for major HFA burns. The author presents the case of a 46-year-old man burned by the spillage of HFA at a high concentration (45-50%). Read More

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January 2020

Hydrofluoric acid burn.

CMAJ 2019 03;191(11):E314

Department of Dermatology, Institute of Dermatology and Venereology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.

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Hydrofluoric Acid: Burns and Systemic Toxicity, Protective Measures, Immediate and Hospital Medical Treatment.

Open Access Maced J Med Sci 2018 Nov 20;6(11):2257-2269. Epub 2018 Nov 20.

Faculty of Technology and Metallurgy, "Ss Cyril and Methodius", University of Skopje, Ruger Boskovic 16, 1000 Skopje, Republic of Macedonia.

Background: Hydrofluoric acid is a commonly used chemical in many industrial branches, but it can also be found as an ingredient in household products such as cleaning agents. Possessing high corrosive potential, HF acid causes burns and tissue necrosis, while when absorbed and distributed through the bloodstream, its extremely high toxic potential is expressed. Acute symptoms are often followed by pain, particularly in the case of skin burns, which intensiveness does not often correlate with the expressiveness of the clinical findings. Read More

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November 2018

Rational treatment of hydrofluoric acid burns of the fingers.

Burns 2018 12 30;44(8):2099-2100. Epub 2018 Oct 30.

Department of Burns & Wound Care Center, 2nd Affiliated Hospital of Zhejiang University, College of Medicine, Hangzhou 310009, China. Electronic address:

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December 2018

Clinical significance of urinary fluoride levels in patients with hydrofluoric acid burns.

Burns 2018 12 28;44(8):2074-2079. Epub 2018 Aug 28.

Department of Burns & Wound Care Centre, 2nd Affiliated Hospital of Zhejiang University, College of Medicine, Hangzhou 310009, China. Electronic address:

Objective: We investigated the urinary fluoride level in patients with hydrofluoric acid (HF) burns of different severities and explored the clinical significance of these levels in the diagnosis of acute HF burn.

Methods: Data from 260 patients with HF burns were collected from the Department of Burns, Zhejiang Quhua Hospital, between July 2006 and June 2016. According to burn severity, patients were divided into non-poisoning, mild poisoning, moderate poisoning, and severe poisoning groups. Read More

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December 2018

Associations of fluoride intake with children's cortical bone mineral and strength measures at age 11.

J Public Health Dent 2018 09 29;78(4):352-359. Epub 2018 Aug 29.

Research Consultant, Morro Bay, CA, USA.

Objectives: There is strong affinity between fluoride and calcium, and mineralized tissues. Investigations of fluoride and bone health during childhood and adolescence show inconsistent results. This analysis assessed associations between period-specific and cumulative fluoride intakes from birth to age 11, and age 11 cortical bone measures obtained using peripheral quantitative computed tomography (pQCT) of the radius and tibia (n = 424). Read More

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September 2018

Full-Thickness Chemical Burn From Trifluoroacetic Acid: A Case Report and Review of the Literature.

Ann Plast Surg 2018 11;81(5):528-530

Regional Burn Center, Santa Clara Valley Medical Center, San Jose, CA.

Trifluoroacetic acid (TFA) burns are an ill-defined entity due to a lack of reported sizable burns from this chemical. In this case report of the largest reported burn from TFA, we demonstrate that TFA causes extensive, progressive full-thickness tissue injury that may initially appear superficial. Trifluoroacetic acid does not seem to involve the systemic toxicities that result from hydrofluoric acid burns, and there is no role for calcium gluconate in acute management based on this case. Read More

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November 2018

Fluoride intake and cortical and trabecular bone characteristics in adolescents at age 17: A prospective cohort study.

Community Dent Oral Epidemiol 2018 12 1;46(6):527-534. Epub 2018 Jul 1.

Department of Epidemiology, College of Public Health, Iowa City, IA, USA.

Objective: To investigate the associations between period-specific and cumulative fluoride (F) intakes from birth to age 17 years, and radial and tibial bone measures obtained using peripheral quantitative computed tomography (pQCT).

Methods: Participants (n = 380) were recruited from hospitals at birth and continued their participation in the ongoing Iowa Fluoride Study/Iowa Bone Development Study until age 17. Fluoride intakes from water, other beverages, selected foods, dietary fluoride supplements and dentifrice were determined every 1. Read More

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December 2018

[Analysis on effects of modified dosage of calcium gluconate on patients with hydrofluoric acid burns not in hands or feet].

Zhonghua Shao Shang Za Zhi 2018 May;34(5):277-282

Department of Burns and Plastic Surgery, Zhejiang Quhua Hospital, Quzhou 324004, China.

To retrospectively explore the effects of modified dosage of calcium gluconate (CG) on the patients with hydrofluoric acid burns not in hands or feet. One hundred and sixty patients with hydrofluoric acid burns not in hands or feet were hospitalized in our burn ward from January 2004 to December 2017. Based on the dosage of CG at different admission time, 76 patients hospitalized from January 2004 to December 2012 were included in traditional group, and 84 patients hospitalized from January 2013 to December 2017 were included in modified group. Read More

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[Analysis on clinical characteristics of 316 patients with hydrofluoric acid burns].

Zhonghua Shao Shang Za Zhi 2018 May;34(5):271-276

Department of Burns and Plastic Surgery, Zhejiang Quhua Hospital, Quzhou 324004, China.

To investigate the clinical characteristics of patients with hydrofluoric acid (HF) burns. Clinical data of 316 patients with HF burns admitted to Zhejiang Quhua Hospital from January 2004 to December 2016 were retrospectively analyzed. Patients were divided into non and mild poisoning group (NMP, =157), moderate poisoning group (MP, =120), and severe and fatal poisoning group (SFP, =39) based on the severity of poisoning. Read More

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[New exploration on clinical treatment of injuries caused by uncommon agents or in extraordinary regions].

Authors:
Y Liu

Zhonghua Shao Shang Za Zhi 2018 May;34(5):263-265

Center of Burns and Plastic Surgery of PLA, Lanzhou General Hospital, Lanzhou 730050, China.

Burns caused by uncommon agents means those caused by other agents except heating power, with special characteristics existing in traumatogenesis, pathophysiology, and clinical manifestation. With the development of social economy, various new techniques and new equipments are springing up. In the practical use, improper operations would become traumatogenic agents and cause various special types of trauma. Read More

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F-Sodium Fluoride Uptake in Abdominal Aortic Aneurysms: The SoFIA Study.

J Am Coll Cardiol 2018 02;71(5):513-523

British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Edinburgh Imaging Facility, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom; National Health Service Lothian, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

Background: Fluorine-18-sodium fluoride (F-NaF) uptake is a marker of active vascular calcification associated with high-risk atherosclerotic plaque.

Objectives: In patients with abdominal aortic aneurysm (AAA), the authors assessed whether F-NaF positron emission tomography (PET) and computed tomography (CT) predicts AAA growth and clinical outcomes.

Methods: In prospective case-control (n = 20 per group) and longitudinal cohort (n = 72) studies, patients with AAA (aortic diameter >40 mm) and control subjects (aortic diameter <30 mm) underwent abdominal ultrasound, F-NaF PET-CT, CT angiography, and calcium scoring. Read More

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February 2018

Extracorporeal membrane oxygenation combined with continuous renal replacement therapy in cutaneous burn and inhalation injury caused by hydrofluoric acid and nitric acid.

Medicine (Baltimore) 2017 Dec;96(48):e8972

Department of Critical Care Medicine, Wujiang First People's Hospital Affiliated to Nantong University Department of Critical Care Medicine, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, China.

Rationale: Hydrofluoric acid (HF) is a highly corrosive agent and can cause corrosive burns. HF can penetrate deeply into tissues through intact skin and the lipid barrier, leading to painful liquefactive necrosis, and inducing hypocalcemia and hypomagnesemia. In this study, we hypothesize that continuous renal replacement therapy (CRRT) may be beneficial in addressing hemodynamic instability in cases of HF poisoning. Read More

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December 2017

Trifluoroacetic acid: Three times the fluoride, three times the toxicity?

Am J Emerg Med 2018 Mar 12;36(3):529.e1-529.e2. Epub 2017 Dec 12.

Division of Medical Toxicology, University of California San Diego, San Diego, CA 92103, USA; Department of Emergency Medicine, University of California San Diego, San Diego, CA 92103, USA.

Trifluoroacetic acid (TFAA) is a carboxylic acid, similar to acetic acid, used industrially and in laboratories. There is a paucity of data regarding exposure and the concern is that toxicity may mimic that of hydrofluoric acid (HF), causing electrolyte abnormalities, dysrhythmia, and cardiac arrest. We report a case of a 27-year-old male that presents with a dermal exposure to TFAA. Read More

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Topical dimethyl sulfoxide inhibits corneal neovascularization and stimulates corneal repair in rabbits following acid burn.

Biotech Histochem 2017 13;92(8):619-636. Epub 2017 Dec 13.

c Department of Surgery , Faculty of Veterinary Medicine, Selçuk University , Konya , Turkey.

Neovascularization of the cornea is characterized by the growth of blood vessels caused by imbalances between angiogenic and anti-angiogenic factors. We investigated whether the expression of Vascular endothelial growth factor (VEGF), Vascular endothelial growth factor receptor (VEGF), Vascular endothelial growth inhibitor (VEGI) receptors, as well as topical drug treatments, participate in regulating corneal neovascularization after corneal damage and remodeling. We used 72 mature male New Zealand rabbits. Read More

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February 2019

Management of a Rare Case With Severe Hydrofluoric Acid Burns: Important Roles of Neutralizers and Continuous Renal Replacement Therapy.

Int J Low Extrem Wounds 2017 Dec 13;16(4):289-295. Epub 2017 Nov 13.

2 Second Affiliated Hospital of Zhejiang University, Hangzhou, China.

Hydrofluoric acid (HF), a dangerous inorganic acid, is widely used in various industries and in daily life. Chemical burns caused by HF exposure occur more frequently in some regions worldwide. It has been reported that some cases with HF burns can be lethal due to the hypertoxicity of HF. Read More

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December 2017

Response to Letter to the Editor "Rational treatment of hydrofluoric acid burns of the fingers".

Burns 2018 12 3;44(8):2100-2101. Epub 2017 Aug 3.

Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

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December 2018

Splashed by a clear liquid.

Emerg Med J 2017 Jul;34(7):475

Department of Public Health, Chung Shan Medical University, Taichung, Taiwan.

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Dimethyl sulfoxide but not indomethacin is efficient for healing in hydrofluoric acid eye burns.

Burns 2017 Feb 27;43(1):232-244. Epub 2016 Oct 27.

University of Selçuk, Faculty of Veterinary Medicine, Department of Surgery, 42075 Konya, Turkey.

Introduction: In this study, we aimed to investigate the effect of indomethacin and dimethyl sulfoxide (DMSO), well-known antioxidant and anti-inflammatory agents, to heal eye burns induced with hydrofluoric acid in rabbits.

Methods: After general anesthesia, the right eye of 72 male New Zealand rabbits were burned by instillation of 2% hydrofluoric acid for 60s. Following this, the eyes were irrigated with 500 cc normal saline. Read More

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February 2017

Is it time for a change in the approach to chemical burns? The role of Diphoterine in the management of cutaneous and ocular chemical injuries.

J Plast Reconstr Aesthet Surg 2017 May 27;70(5):563-567. Epub 2017 Feb 27.

Department of Plastic Surgery, James Cook University Hospital, Middlesbrough, UK.

A multitude of household and occupational compounds have the potential to induce chemical burns to the eye and skin. Without prompt intervention, irreversible visual loss and disfigurement may prevail. Diphoterine and Hexafluorine are amphoteric and hypertonic chelating solutions used in the management of general chemical and hydrofluoric acid burns, respectively. Read More

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[Investigation of emergency capacities for occupational hazard accidents in silicon solar cell producing enterprises].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2016 Nov;34(11):819-821

Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.

To investigate and analyze the influential factors of occupational hazard acci-dents, emergency facilities and emergency management in Silicon solar cell producing enterprises, then to pro-vide scientific strategies. The methods of occupationally healthy field investigating, inspecting of ven-tilation effectiveness, setup of emergency program and wearing chemical suit were used. The mainly occupational hazard accidents factors in the process of Silicon solar cell producing included poisoning chemi-cals, high temperature, onizing radiation and some workplaces. Read More

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November 2016