21,210 results match your criteria Hydatid Cysts


[Management of massive hemoptysis secondary to pulmonary hydatidosis: Special features].

Rev Mal Respir 2020 Jul 9. Epub 2020 Jul 9.

Service de chirurgie thoracique et cardio vasculaire, CHU Habib-Bourguiba, Sfax, Tunisie.

Introduction: Massive hemoptysis is a rare but serious presentation of pulmonary hydatid cysts. The literature reporting this clinical phenomenon is limited to sporadic cases.

Material And Methods: We undertook a retrospective study considering patients who had undergone lung surgery because of hydatid cyst from January 2000 o December 2015 and examined features associated with massive hemoptysis. Read More

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http://dx.doi.org/10.1016/j.rmr.2020.06.005DOI Listing

Pulmonary Echinococcosis in the Terminal Disease of Ferdinand II de' Medici (1610-1670).

Chest 2020 Jul 2;158(1):53-54. Epub 2020 Jul 2.

Institut für Pathologie, Klinikum München-Bogenhausen und München-Schwabing, München, Germany.

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http://dx.doi.org/10.1016/j.chest.2020.01.054DOI Listing

Four pathways for hydatid pulmonary embolism.

J Card Surg 2020 Jul 11. Epub 2020 Jul 11.

Department of Cardiovascular and Thoracic Surgery, Sahloul University Hospital, Sousse, Tunisia.

Introduction: Hydatid pulmonary embolism (HPE) is rare but remains an etiology that needs to be considered and kept in mind, especially in endemic areas, as regards nonthrombotic embolism.

Methods: Between 2000 and 2014, 10 patients were treated in our department for the presence of hydatid material in the pulmonary arterial circulation. Through these 10 cases, we try to assess the radioclinical characteristics and results of the surgical treatment. Read More

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http://dx.doi.org/10.1111/jocs.14754DOI Listing

Nomogram Analysis and Internal Validation to Predict the Risk of Cystobiliary Communication in Patients Undergoing Hydatid Liver Cyst Surgery.

World J Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.

Purpose: Biliary leakage caused by cystobiliary communication (CBC) is a common clinical concern. This study sought to identify predictors of CBC in hepatic cystic echinococcosis (HCE) patients undergoing hydatid liver cyst surgery and establish nomograms to predict CBC.

Methods: A predictive model was established in a training cohort of 310 HCE patients diagnosed between January 2013 and May 2017. Read More

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http://dx.doi.org/10.1007/s00268-020-05661-5DOI Listing

Cardiac hydatid cyst in the right ventricle: An unusual case at a rare site.

J Taibah Univ Med Sci 2020 Jun 25;15(3):249-252. Epub 2020 Mar 25.

Department of Radiology, Faculty of Medicine, Taibah University, Almadinah Almunawwarah, KSA.

Hydatid disease is a parasitic infection by the larval stage of the tapeworm . It affects liver, lungs and rarely other organs. Medical imaging provide the basis for diagnosis. Read More

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http://dx.doi.org/10.1016/j.jtumed.2020.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336018PMC

Primary multiple cerebral hydatid cysts in an immunocompetent, low-risk patient.

IDCases 2020 20;21:e00882. Epub 2020 Jun 20.

Biomedical and Experimental Department, Faculty of Medicine, University of Medicine in Tirana, Address: Rr. Dibres 371, Tirana Albania.

Cystic echinococcosis is a zoonotic infection that occurs worldwide. Humans are infected through ingestion of parasite eggs in contaminated food, water or through direct contact with infected dogs, which are the definite host. Humans serve accidentally as intermediate host, and occurrences are common in children and young adults. Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334456PMC

Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis.

Int J Parasitol Drugs Drug Resist 2020 Jul 2. Epub 2020 Jul 2.

Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Längggassstrasse 122, 3012, Bern, Switzerland.

The current chemotherapeutical treatment against alveolar echinococcosis relies exclusively on benzimidazoles, which are not parasiticidal and can induce severe toxicity. There are no alternative treatment options. To identify novel drugs with activity against Echinococcus multilocularis metacestodes, researchers have studied potentially interesting drug targets (e. Read More

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http://dx.doi.org/10.1016/j.ijpddr.2020.06.002DOI Listing

Thoracoscopic Transdiaphragmatic Excision of Hepatic Hydatid in Patients with Synchronous Pulmonary Hydatid: A Novel Operative Approach.

J Laparoendosc Adv Surg Tech A 2020 Jul 7. Epub 2020 Jul 7.

Department of Pediatric Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

We wish to describe a novel technique of transdiaphragmatic excision of hepatic hydatid in patients with synchronous ipsilateral lung hydatid. Two patients, aged 11 and 6 years, presented with large synchronous hydatid cyst in right lung and liver. Second patient had two large cysts in right lobe of liver in posterior-superior segment of VII and VIII. Read More

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http://dx.doi.org/10.1089/lap.2020.0228DOI Listing

The fox tapeworm, , in grey wolves and dogs in Slovakia: epidemiology and genetic analysis.

J Helminthol 2020 Jul 6;94:e168. Epub 2020 Jul 6.

Institute of Parasitology, Slovak Academy of Sciences, 040 01Košice, Slovakia.

Echinococcus multilocularis, the causative agent of human alveolar echinococcosis, is an important emerging parasite in the northern hemisphere. In epidemiological studies, the highest attention is being paid to foxes as the main reservoir hosts responsible for geographic expansion from multiple focal populations and the invasion of urban habitats, but little information is available on the parasite distribution in other carnivores. Hence, the study was designed to obtain updated information about the occurrence and genetic diversity of E. Read More

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http://dx.doi.org/10.1017/S0022149X20000528DOI Listing

Laboratory results and clinical findings of children with hydatid cyst disease.

Niger J Clin Pract 2020 Jul;23(7):1008-1012

Department of Pediatric Surgery, Firat University School of Medicine, Elazig, Turkey.

Objectives: The relationship hydatid cyst (HC) is a parasitic disease that is endemic worldwide.

Aims: To study the clinical findings and laboratory results of patients with hydatid disease.

Materials And Methods: Total number of patients (n = 78) who underwent surgery for HC disease from 2000 to 2017 were retrospectively evaluated. Read More

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http://dx.doi.org/10.4103/njcp.njcp_531_19DOI Listing

Transcriptomic Features of Echinococcus granulosus Protoscolex during the Encystation Process.

Korean J Parasitol 2020 Jun 26;58(3):287-299. Epub 2020 Jun 26.

Department of Pathogenic Biology, Chongqing Medical University, Chongqing 400016, China.

Cystic echinococcosis (CE) is a zoonotic infection caused by Echinococcus granulosus larvae. It seriously affects the development of animal husbandry and endangers human health. Due to a poor understanding of the cystic fluid formation pathway, there is currently a lack of innovative methods for the prevention and treatment of CE. Read More

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http://dx.doi.org/10.3347/kjp.2020.58.3.287DOI Listing

Prevalence and risk factors associated with human cystic echinococcosis in rural areas, Mongolia.

PLoS One 2020 2;15(7):e0235399. Epub 2020 Jul 2.

Department of Biology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.

Cystic echinococcosis is a chronic, complex and neglected zoonotic disease with considerable socio-economic impact on the affected population. Even though Mongolia is included in the list of high cystic echinococcosis risk countries, there has been very limited research and evidence on the prevalence or prevention of cystic echinococcosis. This field-based cross-sectional study to investigate the prevalence of cystic echinococcosis and its potential risk factors in Mongolia was conducted from April 2016 to March 2018. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235399PLOS
July 2020
3.234 Impact Factor

Cysts and parasites in an abattoir in Northwest Ethiopia; an urgent call for action on "one health".

J Infect Dev Ctries 2020 Jun 29;14(6.1):53S-57S. Epub 2020 Jun 29.

Department of Internal Medicine, University of Gondar, Gondar, Ethiopia.

Introduction: Zoonotic parasitic infections such as echinococcosis affect cattle, sheep and goats by lowering quality of meat and hides as well as decreasing milk production. The burden of such diseases among humans is usually underestimated as they are difficult to diagnose. We used abattoir data to estimate the prevalence of zoonotic parasitic infections in animals. Read More

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http://dx.doi.org/10.3855/jidc.11713DOI Listing

Pulmonary Hydatidosis - An Abandoned Surgical Approach.

Chirurgia (Bucur) 2020 May-Jun;115(3):394-403

Over the years, hydatidosis as a medical-surgical problem, has been researched by many surgeons, trying to find an optimal treatment method that produces as few as possible lung parenchyma lesions and that has as many benefits as possible for the patient. In this article, the authors are bringing to attention, an abandoned surgical method due to its possible complications but which has adapted perfectly to the case describe bellow. We present the case of a 59-year-old patient, with no significant personal pathological history for the underlying disease, who presented with minimal nonspecific symptomatology and with whom the surgical treatment performed was successful practicing the Perez-Fontana technique. Read More

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http://dx.doi.org/10.21614//chirurgia.115.3.394DOI Listing

Abdominal Aortic Occlusion by Hydatid Cysts.

Aorta (Stamford) 2020 Feb 29;8(1):21-22. Epub 2020 Jun 29.

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India.

Hydatid disease is a parasitic infestation caused by the larval stage of . It can infest any part of the body; however, aortic hydatid disease is rare. Involvement of the abdominal aorta is usually due to embolization from cardiac hydatid cysts or direct invasion and can be present at intravascular or intramural locations. Read More

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http://dx.doi.org/10.1055/s-0039-3401994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324249PMC
February 2020

Identification of hydatidosis-related modules and key regulatory genes.

PeerJ 2020 18;8:e9280. Epub 2020 Jun 18.

College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China.

Background: caused by larval of is prevalent all over the world. Although clinical experience showed that the presence of tapeworms could not be found in liver lesions, the repeated infection and aggravation of lesions still occur in the host. Here, this study constructed a multifactor-driven disease-related dysfunction network to explore the potential molecular pathogenesis mechanism in different hosts after infection. Read More

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http://dx.doi.org/10.7717/peerj.9280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306218PMC

Genotyping of Fresh and Parafinized Human Hydatid Cysts Using and Genes in Hamadan Province, West of Iran.

Iran J Parasitol 2020 Apr-Jun;15(2):259-265

Department of Medical Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Hydatidosis is a cosmopolitan zoonotic infection and Hamadan Province in the west of Iran is one of the most important foci of human hydatidosis in Iran. The aim of the current study was the genetic characterization of hydatid cysts operated from humans in Hamadan Province.

Methods: Seventy-two hydatid cysts samples including 50 paraffinized and 22 fresh human hydatid cysts collected from different hospitals in Hamadan Province, western Iran. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311807PMC
June 2020
0.872 Impact Factor

Prevalence of hydatid cyst, Fasciola spp. and Dicrocoelium dendriticum in cattle and sheep slaughtered in Sabzevar abattoir, Iran.

Ann Parasitol 2020 ;66(2):211-216

Faculty of Veterinary Medicine, Ahvaz University, Ahvaz, Iran.

Hydatid cyst, Dicrocoelium dendriticum, and Fasciola spp. are common parasites among ruminants. The current study was conducted to assess the prevalence of these parasites in cattle and sheep slaughtered in Sabzevar abattoir, from April 2014 to March 2016. Read More

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January 2020

Analyzing Signal Peptides for Secretory Production of Recombinant Diagnostic Antigen B8/1 from : An Approach.

Mol Biol Res Commun 2020 Apr;9(1):1-10

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Recombinant AgB8/1 as the most evaluated antigen for serological diagnosis of Cystic Echinococcosis (CE) can provide early and accurate diagnosis for proper management and treatment of the disease. Thus, the secretory production of this recombinant protein is the main goal and the application of signal peptides at the N terminus of the desired protein can help to achieve this goal. The present study applied few bioinformatics tools to evaluate several signal peptides to offer the best candidate for extracellular production of AgB8/1 of in . Read More

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http://dx.doi.org/10.22099/mbrc.2019.35429.1457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275822PMC

Massive hydatid cysts in the lung and liver of a 4-year-old boy.

Clin Case Rep 2020 Jun 9;8(6):1107-1108. Epub 2020 Mar 9.

Department of Hematology and Oncology Shenzhen Children's Hospital Shenzhen China.

Hydatids may persist for years if left undiagnosed. Early identification is challenging, especially in patients from nonendemic regions. It is crucial for clinicians to be aware of the presence of the disease to avoid devastating outcomes. Read More

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http://dx.doi.org/10.1002/ccr3.2763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303846PMC

Human cystic echinococcosis in southwest Iran: a 15-year retrospective epidemiological study of hospitalized cases.

Trop Med Health 2020 19;48:49. Epub 2020 Jun 19.

Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Cystic echinococcosis (CE) is considered as a neglected disease with significant mortality and morbidity in most of the developing countries. The current study aimed to retrospectively assess the demographic and epidemiologic features of human CE surgical cases in a 15-year period in Fars province, southwestern Iran.

Methods: A 15-year (2004-2018) retrospective study was conducted to find out the epidemiological and clinical picture of CE in patients who undergone surgeries for CE in two main hospitals in Fars Province, southwestern Iran. Read More

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http://dx.doi.org/10.1186/s41182-020-00238-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304208PMC

Current status of ex-vivo liver resection and autologous liver transplantation for end-stage hepatic alveolar echinococcosis.

Ann Palliat Med 2020 Jun 12. Epub 2020 Jun 12.

Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province & Organ Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Hepatic alveolar echinococcosis (HAE) is a cosmopolitan zoonosis distribute widely in the northern hemisphere with high estimated 10-year mortality. Radical resection combined with oral albendazole administration are the major methods for HAE treatment, whereas most patients delayed diagnosis and treatment because which was considered as benign disease. For the cases with end-stage HAE could not be treated through conventional hepatectomy, allograft liver transplantation (LT) was regarded as a life-saving technique previously. Read More

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http://dx.doi.org/10.21037/apm-20-184DOI Listing

Comment on Retrospective Study of Cystic Echinococcosis in a Recent Cohort of a Referral Center for Liver Surgery.

J Gastrointest Surg 2020 Jun 22. Epub 2020 Jun 22.

Department of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Elazig Yolu 10. Km, 44280, Malatya, Turkey.

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http://dx.doi.org/10.1007/s11605-020-04690-8DOI Listing

Source attribution of human echinococcosis: A systematic review and meta-analysis.

PLoS Negl Trop Dis 2020 Jun 22;14(6):e0008382. Epub 2020 Jun 22.

Department of Biomedical Science, Institute of Tropical Medicine, Belgium.

Background: A substantial proportion of echinococcosis transmission to humans via contamination of food has been assumed. However, the relative importance of food as a transmission vehicle has previously been estimated through expert opinion rather than empirical data.

Objective: To find and evaluate empirical data that could be used to estimate the source attribution of echinococcosis, in particular the proportion that is transmitted through contaminated food. Read More

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http://dx.doi.org/10.1371/journal.pntd.0008382DOI Listing

Transmission ways of Echinococcus granulosus in rare muscular locations of hydatid disease.

Ann Med Surg (Lond) 2020 Jul 22;55:332-333. Epub 2020 May 22.

Department of General Surgery and Medico, Surgical Specialties, University of Catania, Policlinico Vittorio Emanuele Hospital, Via S. Sofia 78, 95123, Catania, Italy.

The most common modality of transmission of the Echinococcus granulosus is through the alimentary tract. Other ways of infestation are questionable. Airborne penetration of bronchial venules to reach the heart and the systemic circulation has been advocated, but never demonstrated. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.04.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296182PMC

In vitro Scolicidal effects of (Olivier, 1807) venom against the protoscolices of .

Saudi J Biol Sci 2020 Jul 11;27(7):1760-1765. Epub 2020 May 11.

Zoology Department, Faculty of Science, Al-Azhar University, Assuit 71524, Egypt.

Hydatidosis is a zoonotic disease that commonly occurs in several places around the world, especially in the Middle East, due to infection by the larval stage of . This disease impacts an immense effect on the economic and public health of both humans and animals. Despite their effectiveness, the unacceptable side effects and progressive resistance to scolicidal agents may limit their use. Read More

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http://dx.doi.org/10.1016/j.sjbs.2020.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296479PMC

Giant pancreatic mucinous cystadenoma masquerading as renal hydatid disease.

Urol Ann 2020 Apr-Jun;12(2):184-186. Epub 2020 Apr 14.

Department of Urology, MIOT International, Chennai, Tamil Nadu, India.

Mucinous cystic neoplasms of the pancreas are the most common pancreatic cystic neoplasms. A 54-year-old female presented with an abdominal mass and was diagnosed to have a multilocular hydatid cyst from the left kidney by imaging. During surgery, a large thick-walled cyst with multiple loculi was seen arising from the upper pole of the left kidney and adherent to the distal pancreas and splenic vessels. Read More

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http://dx.doi.org/10.4103/UA.UA_51_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292442PMC

Contribution of NIPD-CTDR to the parasitic diseases control and elimination in China: Memory of the 70th anniversary for NIPD-CTDR.

Adv Parasitol 2020 6;110:401-427. Epub 2020 May 6.

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; Key Laboratory of Parasite and Vector Biology, Ministry of Health; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; WHO Collaborating Centre for Tropical Diseases, Shanghai, People's Republic of China. Electronic address:

China has achieved a great success in control and elimination of key parasitic diseases. In 2007, the elimination of lymphatic filariasis was verified by WHO. The schistosomiasis incidence and snail-distributed areas have reduced to the lowest level in the history. Read More

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http://dx.doi.org/10.1016/bs.apar.2020.02.003DOI Listing
May 2020
6.226 Impact Factor

Contribution to the echinococcosis control programme in China by NIPD-CTDR.

Adv Parasitol 2020 3;110:107-144. Epub 2020 Jun 3.

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China; Chinese Center for Tropical Diseases Research, Shanghai, People's Republic of China; WHO Collaborating Centre for Tropical Diseases, Shanghai, People's Republic of China; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, People's Republic of China; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, People's Republic of China. Electronic address:

As a zoonotic parasitosis caused by the parasitism of Echinococcus larvae, echinococcosis imposes serious disease and economic burdens on human beings and society, and is thus a global public health issue. Its complex life history, wide distribution, the combined influence of various epidemic factors, coupled with the unique natural environment, customs, and religious beliefs in endemic areas, pose a huge challenge to the national echinococcosis control programme in China. Accurate early detection and confirmation of diagnosis of echinococcosis, the use of effective drugs, real-time surveillance of the infection status of populations and various hosts, controlling the source of infection, and blocking the route of transmission are of enormous significance for control. Read More

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http://dx.doi.org/10.1016/bs.apar.2020.04.010DOI Listing
June 2020
6.226 Impact Factor

Diagnostic performance of protoscolices antigens in the serodiagnosis of human cystic echinococcosis.

J Immunoassay Immunochem 2020 Jun 18:1-8. Epub 2020 Jun 18.

Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences , Shiraz, Iran.

The development of suitable serological tests for the diagnosis of CE is still necessary. This study aimed to evaluate the efficacy of ELISA in the diagnosis of human cystic echinococcosis (CE), using parasite protoscolices antigens. Liver hydatid cysts were isolated from sheep infected with hydatid cysts and the protoscolices were isolated from the hydatid cyst fluid. Read More

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http://dx.doi.org/10.1080/15321819.2020.1781653DOI Listing

Investigating the effect of gold nanoparticles on hydatid cyst protoscolices under low-power green laser irradiation.

Turk J Surg 2019 Dec 16;35(4):314-320. Epub 2019 Dec 16.

Department of Medical Microbiyology, Necmettin Erbakan University School of Medicine, Konya, Turkey.

Objectives: Various scolicidal agents are applied for the destruction of protoscolices in cysts media. Undesirable complications of the scolicidal agents limit the techniques to treat the cyst disease. Therefore, new non-toxic scolicidal agents are needed. Read More

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http://dx.doi.org/10.5578/turkjsurg.4354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282459PMC
December 2019

Successful robotic radical resection of hepatic echinococcosis located in posterosuperior liver segments.

World J Gastroenterol 2020 Jun;26(21):2831-2838

The Second Department of Hepatopancreatobiliary Surgery, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.

Background: Radical resection is an important treatment method for hepatic echinococcosis. The posterosuperior segments of the liver remain the most challenging region for laparoscopic or robotic hepatectomy.

Aim: To demonstrate the safety and preliminary experience of robotic radical resection of cystic and alveolar echinococcosis in posterosuperior liver segments. Read More

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http://dx.doi.org/10.3748/wjg.v26.i21.2831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284188PMC

Primary Thoracic Wall Hydatid Cyst Extended to the Abdominal wall: A Case Report.

Iran J Med Sci 2020 May;45(3):220-223

Department of Health Care, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran.

Hydatid disease (HD) is an infectious disease caused by echinococcosis. Hydatid cyst (HC) most commonly invades the liver (60-70%) and the lungs (20-25%). However, other parts of the body and even unusual locations can be infected, mimicking a benign lesion that could be easily missed. Read More

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http://dx.doi.org/10.30476/ijms.2019.82036.DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253488PMC

Cholecysto-Hydatid Cyst Fistula: A Rare Cause of Cholangitis.

Am J Case Rep 2020 Jun 17;21:e921914. Epub 2020 Jun 17.

Department of General Surgery, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.

BACKGROUND Cholecysto-hydatid fistula is a rare complication of liver echinococcosis; suppurative cholangitis due to cholecysto-hydatid fistula is even rarer. A multidisciplinary approach is required by radiology and surgery departments during the preoperative diagnosis and treatment processes of these cases. In this paper, a patient treated with suppurative cholangitis due to cholecysto-hydatid fistula is presented. Read More

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http://dx.doi.org/10.12659/AJCR.921914DOI Listing

Prediction and Identification of Epitopes in the Emy162 Antigen of Echinococcus multilocularis.

Acta Parasitol 2020 Jun 15. Epub 2020 Jun 15.

Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, No. 29 Tongren Road, Xining, 810001, China.

Introduction: Alveolar echinococcosis (AE) is a zoonotic disease caused by the parasitism of Echinococcus multilocularis larvae in the intermediate host or the final host. This study aims to identify and analyze the B-cell and T-cell (Th1, Th2 and Th17) epitopes of E. multilocularis antigen Emy162. Read More

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http://dx.doi.org/10.2478/s11686-020-00231-0DOI Listing

Metformin suppresses development of the larval stage targeting the TOR pathway.

Antimicrob Agents Chemother 2020 Jun 15. Epub 2020 Jun 15.

Laboratorio de Zoonosis Parasitarias, Departamento de Biología, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata (UNMdP), Funes 3350, Nivel Cero, (7600) Mar del Plata, Argentina

Alveolar echinococcosis (AE) is a severe disease caused by the larval stage of the tapeworm Current chemotherapeutic treatment options based on benzimidazoles are of limited effectiveness, which underlines the need to find new anti-echinococcosis drugs. Metformin is an anti-hyperglycemic and anti-proliferative agent that shows activity against the related parasite Hence, we assessed the and effects of the drug on Meformin exerted significant dose-dependent killing effects on cultured parasite stem cells and protoscoleces and significantly reduced the de-differentiation of protoscoleces into metacestodes. Likewise, oral administration of metformin (50 mg/kg/day for 8 weeks) was effective in achieving a significant reduction of parasite weight in a secondary murine AE model. Read More

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http://dx.doi.org/10.1128/AAC.01808-19DOI Listing

The correlations between Th1 and Th2 cytokines in human alveolar echinococcosis.

BMC Infect Dis 2020 Jun 15;20(1):414. Epub 2020 Jun 15.

Qinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.

Background: Alveolar echinococcosis (AE) is a zoonotic parasitic disease caused by Echinococcus multilocularis larval tapeworm infections in humans that severely impairs the health of affected patients in the northern hemisphere.

Methods: The expression levels of 20 cytokines associated with AE infection were measured by enzyme-linked immunosorbent assay, and the correlations between these cytokines were analysed in the R programming language.

Results: Serum cytokine levels differed among individuals in both the AE patient and healthy control groups. Read More

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http://dx.doi.org/10.1186/s12879-020-05135-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294603PMC

The immunotherapy with hMASP-2 DNA nanolipoplexes against echinococcosis in experimentally protoscolex-infected mice.

Acta Trop 2020 Jun 12;210:105579. Epub 2020 Jun 12.

Department of Immunology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, China; Key Lab of Preclinical Study for New Drugs of Gansu Province, Lanzhou, 730000, China. Electronic address:

Cystic echinococcosis (CE), a complex and neglected zoonotic infectious disease, is mainly caused by larval tapeworm Echinococcus granulosus with a worldwide distribution. For CE, an effective drug treatment is not yet available. The present study was conducted to evaluate the efficacy of hMASP-2-based immunotherapy against hydatid cysts by using murine model. Read More

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http://dx.doi.org/10.1016/j.actatropica.2020.105579DOI Listing

[Our clinical experience and follow-up results in hydatid cyst cases: a review of 393 patients from a single center].

Rev Bras Anestesiol 2020 May 18. Epub 2020 May 18.

Harran University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Sanliurfa, Turquia.

Background And Objectives: Hydatid cyst is a zoonotic disease caused by Echinococcus granulosus. The aim of our study is to present the clinical features of the patients who were treated for hydatid cyst, determine the interventional techniques and anesthesia methods used and review the occurred complications in detail.

Methods: This study included 393 patients who were followed up and/or treated with the diagnosis of hydatid cyst between January 2013 and November 2018. Read More

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http://dx.doi.org/10.1016/j.bjan.2019.12.013DOI Listing

Robotic resection of hepatic echinococcal cysts: A video vignette.

Asian J Surg 2020 Jun 8. Epub 2020 Jun 8.

Westchester Medical Center, New York Medical College, Department of Surgery, 100 Woods Rd Taylor Pavilion D362 Valhalla, NY, 10595, USA.

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http://dx.doi.org/10.1016/j.asjsur.2020.04.014DOI Listing
June 2020
0.758 Impact Factor

Renal echinococcosis; the parasite, host immune response, diagnosis and management.

J Infect Dev Ctries 2020 May 31;14(5):420-427. Epub 2020 May 31.

Department of Medical Parasitology and Mycology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Renal echinococcosis is a rare parasite-caused disease of humans and animals; it makes up about 4% of confirmed cases of cystic echinococcosis. It is a zoonotic disease that occurs in the intermediate hosts harboring the larval stage, the hydatid cyst, of Echinococcus spp. The renal involvement is often asymptomatic or with unspecific signs. Read More

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http://dx.doi.org/10.3855/jidc.11496DOI Listing

Atypical Presentation of Gastrointestinal Stromal Tumor as Multiple Intra-Abdominal Cysts: A Case Report.

Cureus 2020 May 6;12(5):e7999. Epub 2020 May 6.

Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, IND.

Gastrointestinal stromal tumors (GISTs) are the most common nonepithelial solid neoplasms involving the alimentary tract. We report a case of cystic GIST with multiple cystic metastases. A 61-year-old man presented with upper abdominal pain for two months. Read More

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http://dx.doi.org/10.7759/cureus.7999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274504PMC

The Molecular Epidemiology of Infections.

Pathogens 2020 Jun 8;9(6). Epub 2020 Jun 8.

School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia.

Molecular epidemiology (ME) is the application of molecular tools to determine the causation of disease. With infectious diseases, such as echinococcosis, this applies to identifying and characterising the aetiological agents and elucidating host range. Such an approach has been very successful with the causative agents of echinococcosis, species of , initially by providing a workable and practical taxonomy and subsequently determining transmission patterns in endemic areas. Read More

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http://dx.doi.org/10.3390/pathogens9060453DOI Listing

A Pilot Comparative Study Between Serological and Genetic Investigations in Relationship to Clinical Outcomes on Patients with Cystic Echinococcosis.

Helminthologia 2020 Jun 23;57(2):91-99. Epub 2020 May 23.

Ege University, Faculty of Medicine, Department of Parasitology, 35100 Izmir, Turkey.

The aim of this study was to investigate whether Enzyme-Linked Immunosorbent Assays (ELISA) and Western Blotting (WB) methods could contribute to the assessment of clinical outcomes in genotype-defined cystic echinococcosis (CE) patients. Twenty-nine human isolates and blood samples have been taken from patients who underwent surgery or percutaneous aspiration (PAIR) for therapeutic purposes at Ege University and Manisa Celal Bayar University Hospitals. All sera of patients were screened for the presence of IgG antibodies using in-house approved ELISA and WB methods. Read More

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http://dx.doi.org/10.2478/helm-2020-0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261030PMC

Microsatellite Investigations of Multiple Sensu Stricto Cysts in Single Hosts Reveal Different Patterns of Infection Events between Livestock and Humans.

Pathogens 2020 Jun 5;9(6). Epub 2020 Jun 5.

Anses LRFSN, Wildlife Surveillance and Eco-Epidemiology Unit, National Reference Laboratory for Echinococcus spp.,54220 Malzéville, France.

Cystic echinococcosis (CE) caused by the cestode sensu lato (s.l.) is a worldwide zoonosis and sensu stricto (s. Read More

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http://dx.doi.org/10.3390/pathogens9060444DOI Listing

Screening of Cystic Echinococcosis and Toxocariasis in Urmia Municipal Workers, Northwest Iran.

Infect Disord Drug Targets 2020 Jun 9. Epub 2020 Jun 9.

Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia. Iran.

Background: Echinococcus granulosus and Toxocara spp. the causative agents of hydatid cyst and toxocariasis in human and animals, are zoonotic infection with medical and veterinary significance respectively.

Aim: Herein, we aimed to investigate the seroprevalence of toxocariasis and cystic echinococcosis in Urmia municipal workers (gardeners and sweepers) in 2018 using ELISA assay. Read More

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http://dx.doi.org/10.2174/1871526520666200609121400DOI Listing

[An Update on the Epidemiological Situation of Alveolar Echinococcosis: Recording and Reporting Structures in Austria, Switzerland and Germany].

Gesundheitswesen 2020 Jun 8. Epub 2020 Jun 8.

Klinische Abteilung für Infektionen und Tropenmedizin, Medizinische Universität Wien Universitätsklinik für Innere Medizin I, Wien, Austria.

Objective:  Alveolar echinococcosis (AE) is a rare disease in Austria, Switzerland and Germany (DACh) caused by an infection with the parasite Echinococcus multilocularis. The aim of the study was to describe differences in the detection and reporting systems of alveolar echinococcosis in Austria, Switzerland and Germany and to describe epidemiological trends.

Methodology:  As part of an epidemiological update on 6 September 2019 in Ulm, Germany, experts and representatives discussed differences in the reporting and recording systems as well as the current epidemiological situation. Read More

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http://dx.doi.org/10.1055/a-1138-0692DOI Listing

Autochthonous liver cystic hydatid: Past or actual French shepherd's disease?

IDCases 2020 26;21:e00843. Epub 2020 May 26.

IHU-Méditerranée Infection, Marseille, France.

Autochthonous hydatidosis in France and western Europa are uncommon since the beginning of the 21st century. We report here an authentic indigenous cystic echinococcosis case in a French shepherd. The risk of remerging pathology should not be neglected and measures to interrupt parasite transmission are still relevant. Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264046PMC

Retraction Note to: Antigen based detection of cystic echinococcosis in buffaloes using ELISA and Dot-EIA.

J Parasit Dis 2020 06 29;44(2):496. Epub 2020 Apr 29.

Department of Veterinary Parasitology, Madras Veterinary College, Tamilnadu Veterinary and Animal Sciences University, Chennai, 600 007 India.

[This retracts the article DOI: 10.1007/s12639-016-0762-9.]. Read More

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http://dx.doi.org/10.1007/s12639-020-01225-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244688PMC