922 results match your criteria Human Fertility[Journal]


Oocyte donation disclosure decisions: a longitudinal follow-up at middle childhood.

Hum Fertil (Camb) 2019 Feb 6:1-15. Epub 2019 Feb 6.

e Departments of Obstetrics and Gynecology and Psychiatry and Behavioral Sciences , Northwestern University Feinberg School of Medicine , Chicago , IL , USA.

Few studies have captured oocyte donation (OD) parents' decision processes about intended and actual disclosure over time. Likewise, OD children's perceptions about their family composition during middle childhood are underexplored. To address these gaps, a longitudinally followed cohort of OD recipient families was invited to participate in a qualitative, follow-up study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2019.1567945DOI Listing
February 2019

Association of IL-17 and IL-23 follicular fluid concentrations and gene expression profile in cumulus cells from infertile women at risk for ovarian hyperstimulation syndrome.

Hum Fertil (Camb) 2019 Feb 4:1-7. Epub 2019 Feb 4.

d Department of Immunology , Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences , Yazd , Iran.

This study determined the association between the levels of interleukin (IL)-17 and IL-23 in follicular fluid (FF), as well as their mRNA levels in cumulus cells from infertile women at risk for ovarian hyperstimulation syndrome (OHSS). In this case-controlled study, the control group (n = 40) was infertile women whose partners had male factor infertility, whereas the case group (n = 40) was infertile women at risk of OHSS. IL-17 and IL-23 concentrations in FF were measured using an enzyme-linked immunosorbent assay method, whereas the mRNA expression levels of IL-17 and IL-23 of cumulus cells were determined using RT-PCR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2019.1566648DOI Listing
February 2019
2 Reads

The effects of autologous platelet-rich plasma in repeated implantation failure: a randomized controlled trial.

Hum Fertil (Camb) 2019 Feb 4:1-5. Epub 2019 Feb 4.

a Department of Obstetrics and Gynecology , Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences , Tehran , Iran.

Repeated implantation failure is a major challenge in reproductive medicine and despite several methods that have been described for management, there is little consensus on which is the most effective. This study was conducted to evaluate the effectiveness of autologous platelet-rich plasma in improving the pregnancy rate in repeated implantation failure. Between 2016 and 2017, a total of 138 patients who failed to conceive after 3 or more embryo transfers with high quality embryos and candidate for frozen-thawed embryo transfer were assessed for eligibility to enter the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2019.1569268DOI Listing
February 2019
1 Read

Association of ICAM-1 gene variant rs5498 (1462A>G) with non-obstructive azoospermia.

Hum Fertil (Camb) 2019 Feb 1:1-5. Epub 2019 Feb 1.

c Department of Andrology and Dermatology, Faculty of Medicine , Suez Canal University , Ismailia , Egypt.

The blood testicular barrier (BTB) is a barrier protecting the testes from damage. It also plays an important role in spermatogenesis. The intracellular adhesion molecule-1 (ICAM-1) is a member of the immunoglobulin cell adhesion molecule family and is a constituent component of the BTB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2019.1566646DOI Listing
February 2019

Luteal oestradiol for patients with serum oestradiol levels lower than expected per oocyte.

Hum Fertil (Camb) 2019 Jan 29:1-7. Epub 2019 Jan 29.

a Department of Obstetrics and Gynecology , Uludag University School of Medicine , Bursa , Turkish Republic.

Although the efficiency of progesterone in providing luteal phase support has been established, the role of oestradiol supplementation during the luteal phase remains controversial. We evaluated pregnancy outcomes of patients who had a ratio of serum E2 levels on the hCG day to the number of oocytes retrieved (oestradiol/oocyte ratio - EOR) levels of <100 pg/ml by supporting them with additional oestradiol during the luteal phase. In total, 150 patients with an EOR < 100 pg/ml of oestradiol undergoing antagonist intracytoplasmic sperm injection (ICSI) cycles were randomly assigned into two groups to receive either oral oestradiol (4 mg/d) plus vaginal progesterone (90 mg, 2 × 1/day) (group 1) or vaginal progesterone (90 mg, 2 × 1/d) alone (group 2). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2019.1566647DOI Listing
January 2019

Anonymous Dutch sperm donors releasing their identity.

Hum Fertil (Camb) 2019 Jan 17:1-7. Epub 2019 Jan 17.

a Fiom , 's-Hertogenbosch , the Netherlands.

This study examined the motivations of anonymous Dutch sperm donors to release their identity. It aimed to increase knowledge and encourage donors to become identifiable through a more informed decision, allowing more donor-conceived persons to contact their donors. Since 2010, anonymous sperm donors in the Netherlands can register in the Fiom KID-DNA Database developed by Fiom and Canisius Wilhelmina Hospital (CWZ). Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1564156DOI Listing
January 2019
3 Reads

Can the ethnic differences in IVF cycle outcome be influenced by the impact of BMI?

Hum Fertil (Camb) 2019 Jan 14:1-7. Epub 2019 Jan 14.

a Leeds Fertility, Leeds Teaching Hospital NHS Trust , Leeds , UK.

The objective of this study was to investigate the role of Body Mass Index (BMI) in influencing ethnic variation in IVF outcomes. This retrospective cohort study included women (having BMI between 19 to 30 kg/m) undergoing their first IVF cycle with fresh blastocyst transfer at a single IVF unit between 2010 and 2015. In summary, South Asian women had a lower live birth rate (LBR) (27% vs 44. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1563915DOI Listing
January 2019

Is azoospermia the appropriate standard for post-vasectomy semen analysis? Or an unachievable goal of best practice laboratory guidelines.

Hum Fertil (Camb) 2019 Jan 11:1-7. Epub 2019 Jan 11.

b Vasectomy Provider, Nottingham Road Clinic , Mansfield , UK.

The increasingly stringent laboratory-approach to diagnosing azoospermia for post-vasectomy semen analysis (PVSA) continues to be at odds with the simpler approach desired by clinicians. This study describes the analysis of 10 years of PVSA and discusses the outcome in relation to risk, cost and assesses whether more stringent procedures are required. PVSA was performed on 4788 patients initially using a 2-test strategy (16 and 20 weeks post-surgery), moving to 1 test during 2013-2014. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1562242DOI Listing
January 2019
2 Reads

Altered microRNAs expression levels of sperm and seminal plasma in patients with infertile ejaculates compared with normozoospermic males.

Hum Fertil (Camb) 2019 Jan 11:1-10. Epub 2019 Jan 11.

a Faculty of Medicine, Department of Laboratory Medicine, Division of Clinical Genetics , University of Debrecen , Debrecen , Hungary.

Approximately 15% of couples are unable to conceive after one year of unprotected intercourse. Because sperm can be accessed with ease, it is reasonable to search for non-invasive biomarkers in semen. MicroRNAs are a family of short single-stranded non-coding RNA molecules that are capable of regulating gene expression and causing mRNA degradation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1562241DOI Listing
January 2019

Luteal-phase progesterone supplementation in non-IVF treatment: a survey of physicians providing infertility treatment.

Hum Fertil (Camb) 2019 Jan 10:1-7. Epub 2019 Jan 10.

a Department of Obstetrics and Gynecology , University of Oklahoma Health Sciences Center , Oklahoma City , OK , USA.

We sought to examine current use of, and indications for, progesterone supplementation in the luteal phase of non-in vitro fertilization (non-IVF) infertility treatments among Obstetrician Gynaecologists (OB/GYN) compared to Reproductive Endocrinology and Infertility (REI) Subspecialists. Using a web-based survey, the practices of U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1562240DOI Listing
January 2019
1 Read

Mutation of GALNTL5 gene identified in patients diagnosed with asthenozoospermia.

Hum Fertil (Camb) 2019 Jan 10:1-8. Epub 2019 Jan 10.

a Research Center for Medical Glycoscience , National Institute of Advanced Industrial Science and Technology (AIST) , Tsukuba , Japan.

Asthenozoospermia is commonly observed in infertile men. However, very few causative gene mutations have been identified because an efficient detection method has not been established. We previously identified a patient with asthenozoospermia carrying a heterozygous point deletion in GALNTL5 by detecting an abnormal reduction in the abundance of GALNTL5 and other marker proteins. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1562239DOI Listing
January 2019
5 Reads

Knowledge and decision making about future fertility and oocyte cryopreservation among young women.

Hum Fertil (Camb) 2019 Jan 9:1-10. Epub 2019 Jan 9.

b Duke University Medical Center , Durham , NC , USA.

The objective was to examine what young graduate student women know about preserving fertility/oocyte cryopreservation, and which reproductive resources they use. A prospective, cross-sectional design was used and the study was conducted at a University on the East Coast of the United States. The participants were 278 female graduate students. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1546411DOI Listing
January 2019

The role of stimulation protocol, number of oocytes retrieved with respect to follicular fluid oxidative stress and IVF outcome.

Hum Fertil (Camb) 2019 Jan 8:1-9. Epub 2019 Jan 8.

a Division of Reproductive and Cytotoxicology , ICMR - National Institute of Occupational Health , Ahmedabad , India.

The study was conducted on a population of 203 women attending the IVF clinic, Ahmedabad, India, to explore the role of stimulation protocol and the number of oocytes retrieved on oxidative stress in follicular fluid and IVF outcome. Follicular fluid was collected during ovum pick-up to determine the oxidative stress markers: superoxide dismutase (SOD), malondialdehyde (MDA), glutathione (GSH), total thiols (TT), l-ascorbic acid (AA), total protein, glutathione S-transferase (GST) and glutathione reductase (GRD). The average number of oocytes retrieved was significantly higher in the women receiving a long GnRH agonist protocol compared to GnRH antagonist protocol while the percentage of women with positive IVF outcome was lower in the long agonist protocol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1551630DOI Listing
January 2019
2 Reads
1.018 Impact Factor

High implantation and clinical pregnancy rates with single vitrified-warmed blastocyst transfer and optional aneuploidy testing for all patients.

Hum Fertil (Camb) 2019 Jan 7:1-12. Epub 2019 Jan 7.

a The Bridge Centre , London , UK.

This study reports the results of a 2-year long IVF programme ('One by One') in which all patients (median age 40 years; range 27-45 years) were offered preimplantation genetic testing for aneuploidy (PGT-A) and had all blastocysts vitrified (freeze-only), followed later by single vitrified-warmed blastocyst transfer (vSET) in managed cycles. Between January 2016 and December 2017, a total of 155 patients started 222 treatment cycles and 99 (45%) cycles resulted in one or more vitrified blastocysts (untested or with normal copy number for all chromosomes) available for transfer. Seventeen patients (11%) aged ≤35 years opted out of PGT-A. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1551628DOI Listing
January 2019
4 Reads

Cross-border and domestic surrogacy in the UK context: an exploration of practical and legal decision-making.

Hum Fertil (Camb) 2018 Dec 11:1-12. Epub 2018 Dec 11.

b NGA Law and Brilliant Beginnings , London , UK.

This study aimed to explore UK intending parent's reasons for cross-border and domestic surrogacy, their preparations for the birth and the practical and legal challenges faced after the birth. An online survey was completed by 203 participants, of which 132 had a child born through surrogacy, 33 were in the process of surrogacy and 38 were planning a surrogacy arrangement. The most common reason for pursuing surrogacy in the UK was wanting a relationship with the surrogate (43%; n = 17) and for conducting surrogacy in the USA was because of a better legal framework (97%; n = 60). Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1540801DOI Listing
December 2018
1 Read

Tumour necrosis factor alpha gene polymorphisms in women with recurrent pregnancy loss: a meta-analysis.

Hum Fertil (Camb) 2018 Dec 2:1-11. Epub 2018 Dec 2.

a Korea University College of Medicine , Seoul , Korea.

Tumour necrosis factor alpha (TNF-α) concentration is associated with recurrent pregnancy loss (RPL). Moreover, TNF-α promoter polymorphisms affect cellular TNF-α concentrations. Although several studies on TNF-α polymorphisms have been reported, these studies only define specific loci and result in conflicting conclusions. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1543899DOI Listing
December 2018
8 Reads

Potential effect of inflammation on the failure risk of in vitro fertilization and embryo transfer among infertile women.

Hum Fertil (Camb) 2018 Nov 27:1-9. Epub 2018 Nov 27.

e Reproductive Medical Center , Peking University People's Hospital , Beijing , People's Republic of China.

This study investigated the association between inflammation in infertile women and the risk of IVF-ET failure, as well as the potential effects of various lifestyles on this association. A total of 84 women undergoing IVF-ET in Beijing China were recruited, including 38 women who did not achieve pregnancy after undergoing IVF-ET and 46 women who conceived. Serum samples were collected on the second day of menstruation before the treatment cycle and the inflammatory cytokines (interleukin-1β, interleukin-6, interleukin-8 (IL-8) and monocyte chemotactic protein-1 (MCP-1)) were measured. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1543898DOI Listing
November 2018
6 Reads
1.018 Impact Factor

Assessing the potential of HSPA2 and ADAM2 as two biomarkers for human sperm selection.

Hum Fertil (Camb) 2018 Nov 22:1-11. Epub 2018 Nov 22.

c Monoclonal Antibody Research Center , Avicenna Research Institute (ARI) , ACECR, Tehran , Iran.

Selection of the best sperm, with the least defects, is a critical factor in the success of ART especially in male factor infertility. This study assessed the potential Heat shock protein (HSPA2) and metallopeptidase domain2 (ADAM2) biomarkers for sperm selection. Sperm were obtained from 72 asthenoteratozoospermic and 42 normospermic ejaculates. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1534277DOI Listing
November 2018
9 Reads

No more donor secrets in the genomic age.

Authors:
Allan A Pacey

Hum Fertil (Camb) 2018 Dec;21(4):223-224

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1533065DOI Listing
December 2018

Levels of total antioxidant capacity and 8-hydroxy-2'-deoxyguanosine of serum and follicular fluid in women undergoing in vitro fertilization: focusing on endometriosis.

Hum Fertil (Camb) 2018 Nov 13:1-9. Epub 2018 Nov 13.

a Department of Obstetrics and Gynecology, Faculty of Medicine , University of Pécs , Pécs , Hungary.

This study was designed to evaluate the levels of oxidative stress (OS) markers, total non-enzymatic antioxidant capacity (TAC) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) in the serum and follicular fluid (FF) of patients undergoing in vitro fertilization (IVF). The impact of these biomarkers on IVF outcome was also analysed. Samples were obtained from 61 patients (age: 36. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1535719DOI Listing
November 2018
11 Reads

Ultrasound monitoring during first-cycle treatment with clomifene citrate: a national survey of compliance with NICE.

Hum Fertil (Camb) 2018 Nov 2:1-7. Epub 2018 Nov 2.

a Faculty of Health Sciences & Wellbeing , University of Sunderland , Sunderland , UK.

The National Institute for Health and Care Excellence Clinical Guideline 156 advises that transvaginal ultrasonography (TVUS) should be used in the first cycle of treatment with clomifene citrate, to assess for multifollicular development and hence the risk of multiple pregnancy. This guidance is based on expert opinion rather than research evidence. We conducted a cross-sectional online and postal survey among UK-based consultant gynaecologists and fertility specialists, to explore compliance with this guideline. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1535201DOI Listing
November 2018
1 Read

The interaction between donor-conceived families and their environment: parents' perceptions of societal understanding and attitudes regarding their family-building.

Hum Fertil (Camb) 2018 Nov 2:1-10. Epub 2018 Nov 2.

a Department of Neurobiology Care Sciences and Society , Karolinska Institutet , Huddinge , Sweden.

Disclosure issues in relation to donor conception have mainly been examined in the context of relationships and interaction within donor-conceived families, whilst influences from outside the family, for example societal ones, have been little researched. This study explored the societal experiences of individuals who build their family with the help of donor conception (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1533256DOI Listing
November 2018

Women's experience of social egg freezing: perceptions of success, risks, and 'going it alone'.

Hum Fertil (Camb) 2018 Nov 1:1-7. Epub 2018 Nov 1.

a Centre for Reproduction Research, Faculty of Health and Life Sciences , De Montfort University , Leicester , UK.

Very few studies have explored women's experiences of social egg freezing and the limited primary research on this topic has suggested that users find the process of freezing eggs emotionally challenging. We, therefore, undertook semi-structured interviews with 31 women who identified as undergoing egg freezing for social reasons in order to explore how female users of social egg freezing technology reported their experience of freezing eggs for 'social' reasons. Interviews lasted between 40 minutes and 2 hours, were audio recorded and transcribed verbatim. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1522456DOI Listing
November 2018
3 Reads

CYP1A1 gene (6235T

Hum Fertil (Camb) 2018 Oct 22:1-6. Epub 2018 Oct 22.

c Faculty of Medicine, Department of Obstetrics & Gynecology , Suez Canal University , Ismailia , Egypt.

This case-control study was carried out to examine the association between CYP1A1 gene (6235TRead More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1522455DOI Listing
October 2018
5 Reads

Variations in the inhibin gene in Kashmiri women with primary ovarian insufficiency.

Hum Fertil (Camb) 2018 Oct 19:1-7. Epub 2018 Oct 19.

a Advanced Centre for Human Genetics , Sher-I-Kashmir Institute of Medical Sciences , Srinagar , India.

Inhibin is a glycoprotein produced by granulosa cells and its main function is the negative feedback control of follicle stimulating hormone (FSH) which has an important role in folliculogenesis. Mutation in the INHα gene leading to decreased bioactive inhibin has been associated with primary ovarian insufficiency (POI). The aim of this study was to investigate the role of variations in the INHα gene in increasing the susceptibility to POI in Kashmiri women. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1525502DOI Listing
October 2018
2 Reads

Prevalence of candidate single nucleotide polymorphisms on p53, IL-11, IL-10, VEGF and APOE in patients with repeated implantation failure (RIF) and pregnancy loss (RPL).

Hum Fertil (Camb) 2018 Oct 18:1-6. Epub 2018 Oct 18.

a Molecular Biology, Instituto Bernabeu Biotech , Alicante , Spain.

Recurrent pregnancy loss (RPL; defined as the loss of three or more consecutive pregnancies) and recurrent implantation failure (RIF; when implantation is not achieved after at least three cycles of IVF) are two of the major challenges that reproductive medicine faces. Some polymorphisms have been identified as possible causes of an increased risk of these diseases. This paper studies the prevalence of the polymorphisms in p53, VEGF, IL-10, IL-11 and APOE in RIF and RPL patients that determines the risk for these pathologies. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1524935DOI Listing
October 2018
1 Read

The choice for invasive prenatal tests after subfertility.

Hum Fertil (Camb) 2018 Sep 28:1-8. Epub 2018 Sep 28.

a Department of Obstetrics & Gynaecology, GROW School of Oncology and Developmental Biology , Maastricht University Medical Centre , Maastricht , The Netherlands.

The aim of this study was to test whether women who conceived after a period of subfertility are less likely to undergo invasive prenatal testing (IPT) and determine factors of influence in that decision. We conducted a retrospective study at the Maastricht University Medical Centre (MUMC+) to compare the rates of IPT following abnormal results of combined first trimester screening (cFTS) or second trimester screening (STS), or because of advanced maternal age among women tested for the effect of type and duration of subfertility and history of fertility investigations and/or treatment. We included 977 women who underwent IPT between January 2010 and December 2013. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1517238DOI Listing
September 2018

Failure after fertility treatment: regulation strategies when facing a blocked parenthood goal.

Hum Fertil (Camb) 2018 Sep 26:1-6. Epub 2018 Sep 26.

a School of Psychology , Cardiff University , Cardiff , UK.

Biological parenthood is a central life-goal for many couples that can become blocked when they experience infertility. Many couples who undergo fertility treatment will face failure and consequently have to decide whether to continue with treatment. The present study used the qualitative methodology of Interpretative Phenomenological Analysis to examine self-regulatory approaches that underlie decision-making about continuing treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1510186DOI Listing
September 2018

Female fertility in the cancer setting: availability and quality of online health information.

Hum Fertil (Camb) 2018 Sep 19:1-9. Epub 2018 Sep 19.

b Department of Obstetrics and Gynecology , Northwestern University , Chicago , IL , USA.

As cancer survival rates continue to increase, so does the relevance of starting or expanding a family after cancer, impacting quality of life. However, the option of fertility preservation is not always addressed by physicians before treatment. In the meanwhile, many patients look for health information online. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1506891DOI Listing
September 2018
1 Read

Association between expression of TNF-α, P53 and HIF1α with asthenozoospermia.

Hum Fertil (Camb) 2018 Sep 17:1-7. Epub 2018 Sep 17.

a Department of Reproductive Biotechnology , Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR , Isfahan , Iran.

Reduced sperm motility (asthenozoospermia) accounts for a significant percentage of male infertility and numerous factors have been suggested to explain this phenomenon among which hypoxic and inflammatory markers are the least studied. Therefore, the aim of this study was to assess the main molecular markers involved in hypoxia (P53 and HIF-1α) and inflammation (TNF-α) pathways in infertile men with asthenozoospermia. Expression of these markers were assessed by qRT-PCR, and analysis of data show that mean of hypoxia markers (P53, HIF-1α) and also TNF- α were significantly higher in infertile men with asthenozoospermia compared to fertile men (p < 0. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1493750DOI Listing
September 2018
3 Reads

Influence of body mass index on the relationship between endometrial thickness and pregnancy outcome in single blastocyst frozen embryo transfer cycles.

Hum Fertil (Camb) 2018 Sep 17:1-6. Epub 2018 Sep 17.

a Merrion Fertility Clinic , Dublin , Ireland.

To date there is limited published data assessing whether body mass index (BMI) influences endometrial thickness (ET) and whether this impacts on pregnancy outcomes in single blastocyst FET cycles. The objective of this study, therefore, was to examine the relationship between BMI and ET on the outcome of single blastocyst FET cycles over a five-year period from 2012 until 2016. Patient age, BMI, endometrial pattern and ET prior to FET were recorded. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1504324DOI Listing
September 2018
1 Read

Polymorphisms and haplotypes in VDR gene are associated with female idiopathic infertility.

Hum Fertil (Camb) 2018 Sep 17:1-10. Epub 2018 Sep 17.

a Faculty of Medicine , Institute of Forensic Medicine, University of Belgrade , Belgrade , Serbia.

Unexplained infertility refers to the absence of a definable cause of reproductive failure. Vitamin D receptor (VDR) acts as a transcription factor and regulates a number of vitamin D-responsive genes, including those involved in the immune system. Recent finding that VDR is expressed in reproductive tissues suggests a possible importance of vitamin D in pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1515503DOI Listing
September 2018
5 Reads

Genetic aspects of idiopathic asthenozoospermia as a cause of male infertility.

Hum Fertil (Camb) 2018 Sep 9:1-10. Epub 2018 Sep 9.

a Reproductive Biotechnology Research Centre, Avicenna Research Institute, ACECR , Tehran , Iran.

Infertility is a worldwide problem affecting about 15% of couples trying to conceive. Asthenozoospermia (AZS) is one of the major causes of male infertility, diagnosed by reduced sperm motility, and has no effective therapeutic treatment. To date, a few genes have been found to be associated with AZS in humans and mice, but in most of cases its molecular aetiology remains unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1504325DOI Listing
September 2018
1.020 Impact Factor

Effects of zinc deficiency on impaired spermatogenesis and male infertility: the role of oxidative stress, inflammation and apoptosis.

Hum Fertil (Camb) 2018 Aug 21:1-12. Epub 2018 Aug 21.

a Chemical Injuries Research Center , Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences , Tehran , Iran.

Zinc (Zn) is necessary for the normal function of the male reproductive system and spermatozoa. Although influences of zinc deficiency on impaired spermatogenesis and male infertility have been widely considered, the molecular and cellular mechanisms of these abnormalities are not well understood. General abnormalities, including hypogonadism, Leydig cells damage, deficiency of sex hormone production and impaired spermatogenesis, as well as inflammation, antioxidant depletion, sperm death and male infertility can be observed during zinc deficiency. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1494390DOI Listing
August 2018
1 Read

A pilot study comparing corifollitropin alfa associated with hp-HMG versus high dose rFSH antagonist protocols for ovarian stimulation in poor responders.

Hum Fertil (Camb) 2018 Aug 21:1-8. Epub 2018 Aug 21.

a Service de biologie et médecine de la reproduction CHU de Nantes , Nantes , France.

Does corifollitropin alfa associated with hp-HMG protocol from the beginning of ovarian stimulation perform better than high dose rFSH alone for ovarian stimulation with GnRH antagonist in poor responders? This retrospective, monocentric, case-control pilot study was conducted in 65 poor responders (Bologna criteria) undergoing 2 consecutive IVF cycles. All patients underwent a first ovarian stimulation cycle with high dose rFSH (≥300 IU/day) alone in antagonist protocol, unfortunately leading to poor ovarian response and no pregnancy. The following cycle was performed with 150 μg of corifollitropin alfa associated with daily injections of hp-HMG from the beginning of the cycle. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1504326DOI Listing
August 2018
1 Read

Fertility facts, figures and future plans: an online survey of university students.

Hum Fertil (Camb) 2018 Jul 30:1-8. Epub 2018 Jul 30.

a Victorian Assisted Reproductive Treatment Authority , Melbourne , Australia.

Most people want and expect to have children but lack of awareness about the biological limits of fertility may reduce their chance of achieving their parenthood goals. We surveyed Australian university students' intentions and expectations for future parenthood, knowledge about fertility and preferred sources of fertility information. Male and female students (n = 1215) completed an anonymous 34-item online questionnaire. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1482569DOI Listing

2017 Impact factor.

Authors:
Allan A Pacey

Hum Fertil (Camb) 2018 Sep;21(3):155

a Academic Unit of Reproductive and Developmental Medicine, Department of Oncology and Metabolism , School of Medicine and Biomedical Sciences, University of Sheffield, The Jessop Wing , Sheffield , S10 2SF , UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1494085DOI Listing
September 2018

Fertility-related knowledge and perceptions of fertility education among adolescents and emerging adults: a qualitative study.

Hum Fertil (Camb) 2018 Jul 10:1-9. Epub 2018 Jul 10.

a School of Psychology , Cardiff University , Cardiff, Wales , UK.

Research shows that young people do not know much about their fertility. In the present study, we examined fertility knowledge and perceptions of a fertility educational brochure (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1486514DOI Listing
July 2018
3 Reads

Polycyclic aromatic hydrocarbons exposure and early miscarriage in women undergoing in vitro fertilization-embryo transfer.

Hum Fertil (Camb) 2018 Jun 28:1-6. Epub 2018 Jun 28.

a State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environment and Resources , Guangzhou Institute of Geochemistry, Chinese Academy of Sciences , Guangzhou , China.

Various factors have been reported to be associated with early miscarriages, including microbial infection, chemical toxicity, maternal disorders and genetic abnormalities. In the present study, a prospective cohort study was conducted to investigate whether urinary concentrations of hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) were associated with early pregnancy loss in women undergoing in vitro fertilization-embryo transfer (IVF-ET). Risk of spontaneous pregnancy loss in patients exposed to PAHs was analysed using 40 patients who had experienced early pregnancy loss compared to 40 who had normal live births. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1479888DOI Listing
June 2018
4 Reads
1.020 Impact Factor

Ongoing pregnancies in patients with unexplained recurrent pregnancy loss: adverse obstetric outcomes.

Hum Fertil (Camb) 2018 May 25:1-7. Epub 2018 May 25.

b Department of Biomedical, Experimental and Clinical Sciences, Division of Obstetrics and Gynecology , University of Florence , Florence , Italy.

To investigate the incidence of adverse pregnancy outcomes in couples with an unexplained Recurrent Pregnancy Loss (RPL) history, a retrospective cohort study was conducted between 2014 and 2015. The study group (A) included couples with an unexplained RPL, and the control group (B) was composed of couples who attended the Low-Risk Antenatal Unit during the same period. On the other hand, 53 couples were included in the study group (A) and on the other hand, 65 in the control group (B). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1475754DOI Listing
May 2018
1 Read

Fas and FasL genetic polymorphisms in women with recurrent pregnancy loss: a case-control study.

Hum Fertil (Camb) 2018 May 20:1-6. Epub 2018 May 20.

c Department of Obstetrics and Gynecology , Seoul National University College of Medicine , Seoul , Republic of Korea.

Aberrant apoptosis at the trophoblast-maternal interface and abnormal expression of Fas and Fas ligand (FasL) have been reported in complicated pregnancies with recurrent pregnancy losses (RPL) and preeclampsia. We assessed the prevalence of Fas and FasL genetic polymorphisms in Korean women with RPL and in fertile controls. In total, 306 women with RPL and 298 fertile controls were enrolled. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1467573DOI Listing
May 2018
6 Reads

Psychiatric disorders in women and men up to five years after undergoing assisted reproductive technology treatment - a prospective cohort study.

Hum Fertil (Camb) 2018 May 17:1-6. Epub 2018 May 17.

a Department of Women's and Children's Health , Uppsala University , Uppsala , Sweden.

This is a prospective cohort study with the objective to describe psychiatric disorders, such as any mood and anxiety disorders, in both women and men five years after assisted reproductive technology (ART). The Primary Care Evaluation of Mental Disorders (PRIME-MD) questionnaire, based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), was used as the diagnostic tool to evaluate psychiatric disorders. Logistic regression analysis was used to calculate odds ratios (ORs) and confidence interval (CI) for factors associated with psychiatric disorders at the follow-up. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1474279DOI Listing
May 2018
3 Reads

Cryopreservation of Low Number of Human Spermatozoa; Which is Better: Vapor Phase or Direct Submerging in Liquid Nitrogen?

Hum Fertil (Camb) 2018 May 11:1-7. Epub 2018 May 11.

a Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences , Yazd , Iran.

Cryopreservation and subsequent survival of semen samples with low numbers of human spermatozoa in assisted reproductive technology (ART) facilities can be challenging. The aim of this study was to compare the quality of warmed human spermatozoa following vitrification using direct submerging (DS) in liquid nitrogen (LN) or with LN vapour (V). Normozoospermic ejaculates were prepared by the swim-up technique and the motile sperm fraction was divided into three groups: (i) fresh (control); (ii) DS methods in LN (DS Group); or (iii) cryopreserved in V (Group V). Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14647273.2018.1
Publisher Site
http://dx.doi.org/10.1080/14647273.2018.1456681DOI Listing
May 2018
8 Reads

Reporting on longitudinal live birth rates and cumulative delivery rates are more realistic outcome measures than sperm retrieval rates in couples undergoing mTESE-ICSI.

Hum Fertil (Camb) 2018 May 10:1-6. Epub 2018 May 10.

e Department of Urology , Imperial College NHS Healthcare , London , UK.

The live birth rates (LBRs) in men with non-obstructive azoospermia (NOA) undergoing microdissection TESE (mTESE) are under reported, with surgical sperm retrieval rate often used as the primary outcome measure. We analysed longitudinal and cumulative delivery rates following mTESE- intracytoplasmic sperm injection (ICSI) in NOA. Sperm was retrieved in 45% of patients undergoing mTESE. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1472396DOI Listing

A comparison of the survival and implantation rates of blastocysts that were vitrified on post-fertilization day five, six and seven.

Hum Fertil (Camb) 2018 May 3:1-8. Epub 2018 May 3.

b Department of Gynecology and Obstetric , Uludag University School of Medicine , Bursa , Turkey.

The goal of this retrospective cohort study was to compare survival, implantation, clinical and ongoing pregnancy rates between blastocysts that were vitrified on post-fertilization days 5, 6 and 7. Before vitrification, blastocysts were evaluated in terms of morphology and blastocyst expansion, inner cell mass and trophectoderm quality. They were thawed and transfered in a subsequent artificial cycle. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1468091DOI Listing
May 2018
1 Read

Human charcoal-stripped serum supplementation enhances both the stearoyl-coenzyme a desaturase 1 activity of cumulus cells and the in vitro maturation of oocytes.

Hum Fertil (Camb) 2018 Apr 27:1-7. Epub 2018 Apr 27.

a Department of Medical Biotechnology, Faculty of Advanced Medical Sciences , Tabriz University of Medical Sciences , Tabriz , Iran.

Obtaining a better outcome in assisted reproductive technology remains to be attained. In the case of in vitro fertilization (IVF), oocyte maturity is paramount for achieving a successful pregnancy. Maternal serum supplementation of in vitro maturation (IVM) medium can increase the rate of oocyte IVM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1466400DOI Listing
April 2018
9 Reads

Molecular detection of HHV1-5, AAV and HPV in semen specimens and their impact on male fertility.

Hum Fertil (Camb) 2018 Apr 24:1-6. Epub 2018 Apr 24.

a Virology Department, School of Public Health , Tehran University of Medical Sciences , Tehran , Iran.

Viral infections have been considered as possible destructive factors that influence male fertility. The aim of this study was to determine the prevalence of human herpes viruses 1-5 (HHV1-5), adeno associated virus (AAV) and human papilloma virus (HPV) in semen and whether these influence semen quality. DNA extraction was performed using phenol-chloroform protocol, then three different nested-PCRs were done to detect HHV1-5, AAV and HPV DNAs in the semen samples. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1463570DOI Listing
April 2018
1 Read

IVF's 40th birthday.

Authors:
Allan A Pacey

Hum Fertil (Camb) 2018 06;21(2):85

a Academic Unit of Reproductive and Developmental Medicine, Department of Oncology and Metabolism, School of Medicine and Biomedical Sciences, University of Sheffield, The Jessop Wing , Sheffield , S10 2SF , UK .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1461184DOI Listing

Early outcomes of a municipally funded oocyte cryopreservation programme in Japan.

Hum Fertil (Camb) 2018 Apr 19:1-7. Epub 2018 Apr 19.

a Department of Obstetrics and Gynecology , Juntendo University Urayasu Hospital , Urayasu City , Chiba , Japan.

One factor explaining the declining birth rate in Japan is the social advancement of women. Women are delaying marriage and childbirth, with many then facing so-called 'social infertility'. Advanced infertility treatment options, such as in vitro fertilization, are available, but the costs are high. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1464215DOI Listing
April 2018
1 Read

Non-commercial surrogacy among close relatives in Vietnam: policy and ethical implications.

Authors:
Yuri Hibino

Hum Fertil (Camb) 2018 Apr 19:1-4. Epub 2018 Apr 19.

a Department of Medical Science , Kanazawa University , Kanazawa City , Japan.

Altruistic surrogacy among close relatives has been legal in Vietnam since the beginning of 2015. Following the revision of the Marriage and Family Law, there have been dozens of cases of surrogacy, and instances of successful pregnancy and childbirth have also been reported. Although surrogacy was completely prohibited in 2003, numerous local brokers offered commercial surrogacy services. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14647273.2018.1461936DOI Listing
April 2018
2 Reads