4,256 results match your criteria Human Brain Mapping[Journal]


Perfusion weighted imaging using combined gradient/spin echo EPIK: Brain tumour applications in hybrid MR-PET.

Hum Brain Mapp 2019 Feb 13. Epub 2019 Feb 13.

Institute of Neuroscience and Medicine - 4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, Jülich, Germany.

Advanced perfusion-weighted imaging (PWI) methods that combine gradient echo (GE) and spin echo (SE) data are important tools for the study of brain tumours. In PWI, single-shot, EPI-based methods have been widely used due to their relatively high imaging speed. However, when used with increasing spatial resolution, single-shot EPI methods often show limitations in whole-brain coverage for multi-contrast applications. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24537
Publisher Site
http://dx.doi.org/10.1002/hbm.24537DOI Listing
February 2019
2 Reads

Parts-based representations of perceived face movements in the superior temporal sulcus.

Hum Brain Mapp 2019 Feb 13. Epub 2019 Feb 13.

Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.

Facial motion is a primary source of social information about other humans. Prior fMRI studies have identified regions of the superior temporal sulcus (STS) that respond specifically to perceived face movements (termed fSTS), but little is known about the nature of motion representations in these regions. Here we use fMRI and multivoxel pattern analysis to characterize the representational content of the fSTS. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24540
Publisher Site
http://dx.doi.org/10.1002/hbm.24540DOI Listing
February 2019
2 Reads

Resting state connectivity differences in eyes open versus eyes closed conditions.

Hum Brain Mapp 2019 Feb 5. Epub 2019 Feb 5.

The Mind Research Network, Albuquerque, New Mexico.

Functional magnetic resonance imaging data are commonly collected during the resting state. Resting state functional magnetic resonance imaging (rs-fMRI) is very practical and applicable for a wide range of study populations. Rs-fMRI is usually collected in at least one of three different conditions/tasks, eyes closed (EC), eyes open (EO), or eyes fixated on an object (EO-F). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24539DOI Listing
February 2019

Recreational use of GHB is associated with alterations of resting state functional connectivity of the central executive and default mode networks.

Hum Brain Mapp 2019 Feb 5. Epub 2019 Feb 5.

Department of Psychiatry, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

Gamma-hydroxybutyrate acid (GHB) is a recreational drug with a high addictive potential. Severe side effects such as GHB-induced coma are common and linked to increased emergency room attendances. Task-based functional-imaging studies have revealed an association between the regular use of GHB and multiple GHB-induced comas, and altered neurocognitive function. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24532DOI Listing
February 2019

Cortical pattern of reduced perfusion in hearing loss revealed by ASL-MRI.

Hum Brain Mapp 2019 Feb 4. Epub 2019 Feb 4.

Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Salerno, Italy.

Age-related hearing loss (HL) can be related to brain dysfunction or structural damage and may result in cerebral metabolic/perfusion abnormalities. Arterial spin labeling (ASL) magnetic resonance imaging (MRI) allows investigating noninvasively brain perfusion changes. Pseudocontinuous ASL and T1-weighted MRI (at 3 T) and neuropsychological testing (Montreal Cognitive Assessment) were performed in 31 HL (age range = 47-77 years, mean age ± SD = 63. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24538DOI Listing
February 2019

The dynamic contribution of the high-level visual cortex to imagery and perception.

Hum Brain Mapp 2019 Jan 31. Epub 2019 Jan 31.

Cognitive and Motor Rehabilitation and Neuroimaging Unit, IRCCS Fondazione Santa Lucia, Rome, Italy.

Mental imagery and visual perception rely on the same content-dependent brain areas in the high-level visual cortex (HVC). However, little is known about dynamic mechanisms in these areas during imagery and perception. Here we disentangled local and inter-regional dynamic mechanisms underlying imagery and perception in the HVC and the hippocampus (HC), a key region for memory retrieval during imagery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24535DOI Listing
January 2019

Frequency of alpha oscillation predicts individual differences in perceptual stability during binocular rivalry.

Hum Brain Mapp 2019 Jan 31. Epub 2019 Jan 31.

Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota.

When ambiguous visual stimuli have multiple interpretations, human perception can alternate between them, producing perceptual multistability. There is a large variation between individuals in how long stable percepts endure, on average, between switches, but the underlying neural basis of this individual difference in perceptual dynamics remains obscure. Here, we show that in one widely studied multistable paradigm-binocular rivalry-perceptual stability in individuals is predicted by the frequency of their neural oscillations within the alpha range (7-13 Hz). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24533DOI Listing
January 2019
1 Read

Near-infrared spectroscopy reveals neural perception of vocal emotions in human neonates.

Hum Brain Mapp 2019 Jan 30. Epub 2019 Jan 30.

Faculty of Foreign Languages, Ningbo University, Ningbo, China.

Processing affective prosody, that is the emotional tone of a speaker, is fundamental to human communication and adaptive behaviors. Previous studies have mainly focused on adults and infants; thus the neural mechanisms underlying the processing of affective prosody in newborns remain unclear. Here, we used near-infrared spectroscopy to examine the ability of 0-to-4-day-old neonates to discriminate emotions conveyed by speech prosody in their maternal language and a foreign language. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24534
Publisher Site
http://dx.doi.org/10.1002/hbm.24534DOI Listing
January 2019
6 Reads

Private but not social information validity modulates social conformity bias.

Hum Brain Mapp 2019 Jan 30. Epub 2019 Jan 30.

School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.

It is well established that human behaviors are susceptible to others' opinions. However, optimal decision theory mandates choices be made upon the estimated validities of different information sources and little is known about whether and how people could wean themselves off social conformity bias, especially when the social signals are uninformative. Here, we asked subjects to participate in a probabilistic urn guessing task based on their private information as well as observed choices from their partners. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24536DOI Listing
January 2019
5.969 Impact Factor

Effective connectivity in the default mode network is distinctively disrupted in Alzheimer's disease-A simultaneous resting-state FDG-PET/fMRI study.

Hum Brain Mapp 2019 Jan 30. Epub 2019 Jan 30.

TUM-Neuroimaging Center (TUM-NIC), Klinikum Rechts der Isar, München, Germany.

A prominent finding of postmortem and molecular imaging studies on Alzheimer's disease (AD) is the accumulation of neuropathological proteins in brain regions of the default mode network (DMN). Molecular models suggest that the progression of disease proteins depends on the directionality of signaling pathways. At network level, effective connectivity (EC) reflects directionality of signaling pathways. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24517DOI Listing
January 2019
2 Reads

Neural mechanisms of training an auditory event-related potential task in a brain-computer interface context.

Hum Brain Mapp 2019 Jan 28. Epub 2019 Jan 28.

Institute of Psychology, University of Würzburg, Würzburg, Germany.

Effective use of brain-computer interfaces (BCIs) typically requires training. Improved understanding of the neural mechanisms underlying BCI training will facilitate optimisation of BCIs. The current study examined the neural mechanisms related to training for electroencephalography (EEG)-based communication with an auditory event-related potential (ERP) BCI. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24531
Publisher Site
http://dx.doi.org/10.1002/hbm.24531DOI Listing
January 2019
5 Reads
5.969 Impact Factor

Neural networks for sentence comprehension and production: An ALE-based meta-analysis of neuroimaging studies.

Hum Brain Mapp 2019 Jan 28. Epub 2019 Jan 28.

Center for the Neurobiology of Language Recovery, Northwestern University, Evanston, Illinois.

Comprehending and producing sentences is a complex endeavor requiring the coordinated activity of multiple brain regions. We examined three issues related to the brain networks underlying sentence comprehension and production in healthy individuals: First, which regions are recruited for sentence comprehension and sentence production? Second, are there differences for auditory sentence comprehension vs. visual sentence comprehension? Third, which regions are specifically recruited for the comprehension of syntactically complex sentences? Results from activation likelihood estimation (ALE) analyses (from 45 studies) implicated a sentence comprehension network occupying bilateral frontal and temporal lobe regions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24523DOI Listing
January 2019
1 Read

Transient states of network connectivity are atypical in autism: A dynamic functional connectivity study.

Hum Brain Mapp 2019 Jan 25. Epub 2019 Jan 25.

Brain Development Imaging Laboratories, Department of Psychology, San Diego State University, San Diego, California.

There is ample evidence of atypical functional connectivity (FC) in autism spectrum disorders (ASDs). However, transient relationships between neural networks cannot be captured by conventional static FC analyses. Dynamic FC (dFC) approaches have been used to identify repeating, transient connectivity patterns ("states"), revealing spatiotemporal network properties not observable in static FC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24529DOI Listing
January 2019
1 Read

Evolution of white matter tract microstructure across the life span.

Hum Brain Mapp 2019 Jan 23. Epub 2019 Jan 23.

Laboratory of Research in Neuroimaging (LREN) - Department of Clinical Neurosciences - CHUV, University of Lausanne, Lausanne, Switzerland.

The human brain undergoes dramatic structural change over the life span. In a large imaging cohort of 801 individuals aged 7-84 years, we applied quantitative relaxometry and diffusion microstructure imaging in combination with diffusion tractography to investigate tissue property dynamics across the human life span. Significant nonlinear aging effects were consistently observed across tracts and tissue measures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24522DOI Listing
January 2019

Cortical and structural-connectivity damage correlated with impaired syntactic processing in aphasia.

Hum Brain Mapp 2019 Jan 22. Epub 2019 Jan 22.

Department of Communication Sciences and Disorders, University of South Carolina, Columbia, South Carolina.

Agrammatism in aphasia is not a homogeneous syndrome, but a characterization of a nonuniform set of language behaviors in which grammatical markers and complex syntactic structures are omitted, simplified, or misinterpreted. In a sample of 71 left-hemisphere stroke survivors, syntactic processing was quantified with the Northwestern Assessment of Verbs and Sentences (NAVS). Classification analyses were used to assess the relation between NAVS performance and morphosyntactically reduced speech in picture descriptions. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24514
Publisher Site
http://dx.doi.org/10.1002/hbm.24514DOI Listing
January 2019
13 Reads

Generalizing age effects on brain structure and cognition: A two-study comparison approach.

Hum Brain Mapp 2019 Jan 22. Epub 2019 Jan 22.

University Research Priority Program Dynamics of Healthy Aging, University of Zurich, Zurich, Switzerland.

Normal aging is accompanied by an interindividually variable decline in cognitive abilities and brain structure. This variability, in combination with methodical differences and differences in sample characteristics across studies, pose a major challenge for generalizability of results from different studies. Therefore, the current study aimed at cross-validating age-related differences in cognitive abilities and brain structure (measured using cortical thickness [CT]) in two large independent samples, each consisting of 228 healthy older adults aged between 65 and 85 years: the Longitudinal Healthy Aging Brain (LHAB) database (University of Zurich, Switzerland) and the 1000BRAINS (Research Centre Jülich, Germany). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24524DOI Listing
January 2019

Structural and functional asymmetry of medial temporal subregions in unilateral temporal lobe epilepsy: A 7T MRI study.

Hum Brain Mapp 2019 Jan 21. Epub 2019 Jan 21.

Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.

Mesial temporal lobe epilepsy (TLE) is a common neurological disorder affecting the hippocampus and surrounding medial temporal lobe (MTL). Although prior studies have analyzed whole-brain network distortions in TLE patients, the functional network architecture of the MTL at the subregion level has not been examined. In this study, we utilized high-resolution 7T T2-weighted magnetic resonance imaging (MRI) and resting-state BOLD-fMRI to characterize volumetric asymmetry and functional network asymmetry of MTL subregions in unilateral medically refractory TLE patients and healthy controls. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24530
Publisher Site
http://dx.doi.org/10.1002/hbm.24530DOI Listing
January 2019
3 Reads

Modular preprocessing pipelines can reintroduce artifacts into fMRI data.

Hum Brain Mapp 2019 Jan 21. Epub 2019 Jan 21.

Biostatistics, Johns Hopkins School of Public Health, Baltimore, Maryland.

The preprocessing pipelines typically used in both task and resting-state functional magnetic resonance imaging (rs-fMRI) analysis are modular in nature: They are composed of a number of separate filtering/regression steps, including removal of head motion covariates and band-pass filtering, performed sequentially and in a flexible order. In this article, we illustrate the shortcomings of this approach, as we show how later preprocessing steps can reintroduce artifacts previously removed from the data in prior preprocessing steps. We show that each regression step is a geometric projection of data onto a subspace, and that performing a sequence of projections can move the data into subspaces no longer orthogonal to those previously removed, reintroducing signal related to nuisance covariates. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24528
Publisher Site
http://dx.doi.org/10.1002/hbm.24528DOI Listing
January 2019
3 Reads

Intermittent theta burst stimulation over right somatosensory larynx cortex enhances vocal pitch-regulation in nonsingers.

Hum Brain Mapp 2019 Jan 21. Epub 2019 Jan 21.

Institute of Medical Psychology and Behavioral Neurobiology, Eberhard Karls University Tübingen, Tübingen, Germany.

While the significance of auditory cortical regions for the development and maintenance of speech motor coordination is well established, the contribution of somatosensory brain areas to learned vocalizations such as singing is less well understood. To address these mechanisms, we applied intermittent theta burst stimulation (iTBS), a facilitatory repetitive transcranial magnetic stimulation (rTMS) protocol, over right somatosensory larynx cortex (S1) and a nonvocal dorsal S1 control area in participants without singing experience. A pitch-matching singing task was performed before and after iTBS to assess corresponding effects on vocal pitch regulation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24515DOI Listing
January 2019
1 Read

Brain network dynamics in schizophrenia: Reduced dynamism of the default mode network.

Hum Brain Mapp 2019 Jan 21. Epub 2019 Jan 21.

Department of Biomedical Engineering, The University of Melbourne, Victoria, Australia.

Complex human behavior emerges from dynamic patterns of neural activity that transiently synchronize between distributed brain networks. This study aims to model the dynamics of neural activity in individuals with schizophrenia and to investigate whether the attributes of these dynamics associate with the disorder's behavioral and cognitive deficits. A hidden Markov model (HMM) was inferred from resting-state functional magnetic resonance imaging (fMRI) data that was temporally concatenated across individuals with schizophrenia (n = 41) and healthy comparison individuals (n = 41). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24519DOI Listing
January 2019
3 Reads

Gray matter volume covariance networks associated with dual-task cost during walking-while-talking.

Hum Brain Mapp 2019 Jan 21. Epub 2019 Jan 21.

Departments of Medicine, Albert Einstein College of Medicine, Bronx, New York.

We studied gray matter volume covariance networks associated with normal pace walking (NPW) speed and dual-task costs (DTCs) during walking-while-talking (WWT)-a mobility stress test that involves walking while reciting alternate letters of the alphabet. Using a multivariate covariance-based analytic approach, we identified gray matter networks associated with NPW speed (mean 102.1 cm/s ±22. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24520DOI Listing
January 2019
2 Reads

Classification of schizophrenia by intersubject correlation in functional connectome.

Hum Brain Mapp 2019 Jan 21. Epub 2019 Jan 21.

Laboratory of Cognitive Neuropsychology, Collaborative Innovation Centre of Neuropsychiatric Disorder and Mental Health, Hefei, China.

Functional connectomes have been suggested as fingerprinting for individual identification. Accordingly, we hypothesized that subjects in the same phenotypic group have similar functional connectome features, which could help to discriminate schizophrenia (SCH) patients from healthy controls (HCs) and from depression patients. To this end, we included resting-state functional magnetic resonance imaging data of SCH, depression patients, and HCs from three centers. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24527
Publisher Site
http://dx.doi.org/10.1002/hbm.24527DOI Listing
January 2019
5 Reads

Pregnancy and adolescence entail similar neuroanatomical adaptations: A comparative analysis of cerebral morphometric changes.

Hum Brain Mapp 2019 Jan 20. Epub 2019 Jan 20.

Brain and Development Laboratory, Leiden University, Leiden, The Netherlands.

Mapping the impact of pregnancy on the human brain is essential for understanding the neurobiology of maternal caregiving. Recently, we found that pregnancy leads to a long-lasting reduction in cerebral gray matter volume. However, the morphometric features behind the volumetric reductions remain unexplored. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24513
Publisher Site
http://dx.doi.org/10.1002/hbm.24513DOI Listing
January 2019
4 Reads
5.969 Impact Factor

An average sliding window correlation method for dynamic functional connectivity.

Hum Brain Mapp 2019 Jan 19. Epub 2019 Jan 19.

The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, New Mexico.

Sliding window correlation (SWC) is utilized in many studies to analyze the temporal characteristics of brain connectivity. However, spurious artifacts have been reported in simulated data using this technique. Several suggestions have been made through the development of the SWC technique. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24509
Publisher Site
http://dx.doi.org/10.1002/hbm.24509DOI Listing
January 2019
4 Reads

The supplementary motor area modulates interhemispheric interactions during movement preparation.

Hum Brain Mapp 2019 Jan 17. Epub 2019 Jan 17.

Faculté de Médecine, INSERM U 1127, CNRS UMR 7225, Institut du Cerveau et de la Moelle épinière, Sorbonne Université, Paris, France.

The execution of coordinated hand movements requires complex interactions between premotor and primary motor areas in the two hemispheres. The supplementary motor area (SMA) is involved in movement preparation and bimanual coordination. How the SMA controls bimanual coordination remains unclear, although there is evidence suggesting that the SMA could modulate interhemispheric interactions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24512DOI Listing
January 2019

Differences in theta coherence between spatial and nonspatial attention using intracranial electroencephalographic signals in humans.

Hum Brain Mapp 2019 Jan 15. Epub 2019 Jan 15.

Department of Biomedical Engineering, Hanyang University, Seoul, Korea.

A number of previous studies revealed the importance of the frontoparietal network for attention and preparatory top-down control. Here, we investigated the theta (7-9 Hz) coherence of the right frontoparietal networks to explore the differences in connectivity changes for the right frontoparietal regions during spatial attention (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24526DOI Listing
January 2019

Characterization of brain network supporting episodic memory in the absence of one medial temporal lobe.

Hum Brain Mapp 2019 Jan 15. Epub 2019 Jan 15.

Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, Korea.

How the brain supports normal episodic memory function without medial temporal lobe (MTL) structures has not been well characterized, which could provide clues for new therapeutic targets for people with MTL dysfunction-related memory impairment. To characterize brain network supporting effective episodic memory function in the absence of unilateral MTL, we investigated the whole-brain cortical interactions during functional magnetic resonance imaging memory encoding paradigms of words and figures in patients who showed a normal range of memory capacity following unilateral MTL resection and healthy controls (HC). Compared to the HC, the patients showed less activation in the left inferior frontal areas and right thalamus together with greater activation in the many cortical areas including the medial prefrontal cortex (mPFC). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24516DOI Listing
January 2019

Frontostriatal network dysfunction as a domain-general mechanism underlying phantom perception.

Hum Brain Mapp 2019 Jan 15. Epub 2019 Jan 15.

School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas.

In the present study, we use resting state fMRI to investigate whether nucleus accumbens (NAc) and extended frontostriatal networks are involved in the pathology of auditory phantom perception, i.e., tinnitus, through a study of functional connectivity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24521DOI Listing
January 2019

Maturation changes the excitability and effective connectivity of the frontal lobe: A developmental TMS-EEG study.

Hum Brain Mapp 2019 Jan 15. Epub 2019 Jan 15.

Department of Clinical Neurophysiology, Kuopio University Hospital, Kuopio, Finland.

The combination of transcranial magnetic stimulation with simultaneous electroencephalography (TMS-EEG) offers direct neurophysiological insight into excitability and connectivity within neural circuits. However, there have been few developmental TMS-EEG studies to date, and they all have focused on primary motor cortex stimulation. In the present study, we used navigated high-density TMS-EEG to investigate the maturation of the superior frontal cortex (dorsal premotor cortex [PMd]), which is involved in a broad range of motor and cognitive functions known to develop with age. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24525DOI Listing
January 2019
1 Read

Dynamic changes of functional segregation and integration in vulnerability and resilience to schizophrenia.

Hum Brain Mapp 2019 Jan 15. Epub 2019 Jan 15.

Department of Psychiatry, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.

Schizophrenia (SZ) is a highly heritable disease with neurodevelopmental origins and significant functional brain network dysfunction. Functional network is heavily influenced by neurodevelopment processes and can be characterized by the degree of segregation and integration. This study examines functional segregation and integration in SZ and their first-degree relatives (high risk [HR]) to better understand the dynamic changes in vulnerability and resiliency, and disease markers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24518DOI Listing
January 2019
6 Reads

Quantitative neuroimaging measures of myelin in the healthy brain and in multiple sclerosis.

Hum Brain Mapp 2019 Jan 15. Epub 2019 Jan 15.

Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.

Quantitative magnetic resonance imaging (MRI) techniques have been developed as imaging biomarkers, aiming to improve the specificity of MRI to underlying pathology compared to conventional weighted MRI. For assessing the integrity of white matter (WM), myelin, in particular, several techniques have been proposed and investigated individually. However, comparisons between these methods are lacking. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24510DOI Listing
January 2019

Identifying the neural correlates of doorway freezing in Parkinson's disease.

Hum Brain Mapp 2019 Jan 13. Epub 2019 Jan 13.

Parkinson's Disease Research Clinic, Brain and Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.

Freezing of gait (FOG) in Parkinson's disease (PD) is frequently triggered upon passing through narrow spaces such as doorways. However, despite being common the neural mechanisms underlying this phenomenon are poorly understood. In our study, 19 patients who routinely experience FOG performed a previously validated virtual reality (VR) gait paradigm where they used foot-pedals to navigate a series of doorways. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24506DOI Listing
January 2019
5 Reads

Trait Openness and serotonin 2A receptors in healthy volunteers: A positron emission tomography study.

Hum Brain Mapp 2019 Jan 11. Epub 2019 Jan 11.

Neurobiology Research Unit, Rigshospitalet, Copenhagen, Denmark.

Recent research found lasting increases in personality trait Openness in healthy individuals and patients after administration of the serotonin 2A receptor (5-HT R) agonist psilocybin. However, no studies have investigated whether 5-HT R availability as imaged using positron emission tomography (PET) is associated with this trait. In 159 healthy individuals (53 females), the association between 5-HT R binding in neocortex imaged with [ F]altanserin or [ C]Cimbi-36 PET and personality trait Openness was investigated using linear regression models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24511DOI Listing
January 2019

Connectome-based model predicts individual differences in propensity to trust.

Hum Brain Mapp 2019 Jan 11. Epub 2019 Jan 11.

School of Systems Biology, George Mason University, Fairfax, Virginia.

Trust constitutes a fundamental basis of human society and plays a pivotal role in almost every aspect of human relationships. Although enormous interest exists in determining the neuropsychological underpinnings of a person's propensity to trust utilizing task-based fMRI; however, little progress has been made in predicting its variations by task-free fMRI based on whole-brain resting-state functional connectivity (RSFC). Here, we combined a one-shot trust game with a connectome-based predictive modeling approach to predict propensity to trust from whole-brain RSFC. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24503
Publisher Site
http://dx.doi.org/10.1002/hbm.24503DOI Listing
January 2019
6 Reads
5.969 Impact Factor

Moral contagion: Devaluation effect of immorality on hypothetical judgments of economic value.

Hum Brain Mapp 2019 Jan 9. Epub 2019 Jan 9.

Department of Psychology, College of Psychology and Sociology, Shenzhen University, Shenzhen, China.

Moral contagion is a phenomenon in which individuals or objects take on the moral essence of the people who are associated with them. Previous studies have found that individuals value objects associated with moral and likable people more than those associated with immoral and dislikable people. However, the neural mechanisms underlying this "moral contagion effect" have not yet been explored. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24508DOI Listing
January 2019

Dynamic functional network connectivity in Huntington's disease and its associations with motor and cognitive measures.

Hum Brain Mapp 2019 Jan 7. Epub 2019 Jan 7.

Department of Translational Neuroscience, The Mind Research Network, Albuquerque, New Mexico.

Dynamic functional network connectivity (dFNC) is an expansion of traditional, static FNC that measures connectivity variation among brain networks throughout scan duration. We used a large resting-state fMRI (rs-fMRI) sample from the PREDICT-HD study (N = 183 Huntington disease gene mutation carriers [HDgmc] and N = 78 healthy control [HC] participants) to examine whole-brain dFNC and its associations with CAG repeat length as well as the product of scaled CAG length and age, a variable representing disease burden. We also tested for relationships between functional connectivity and motor and cognitive measurements. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24504DOI Listing
January 2019
2 Reads

EEG-based age-prediction models as stable and heritable indicators of brain maturational level in children and adolescents.

Hum Brain Mapp 2019 Jan 4. Epub 2019 Jan 4.

Department of Psychiatry, Amsterdam Universitair Medisch Centrum, Amsterdam Neuroscience, Amsterdam, The Netherlands.

The human brain shows remarkable development of functional brain activity from childhood to adolescence. Here, we investigated whether electroencephalogram (EEG) recordings are suitable for predicting the age of children and adolescents. Moreover, we investigated whether overestimation or underestimation of age was stable over longer time periods, as stable prediction error can be interpreted as reflecting individual brain maturational level. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24501DOI Listing
January 2019
1 Read

Amyloid burden accelerates white matter degradation in cognitively normal elderly individuals.

Hum Brain Mapp 2019 Jan 3. Epub 2019 Jan 3.

Center for Cognitive Neuroscience, Neuroscience and Behavioural Disorders Program, Duke-National University of Singapore Graduate Medical School, Singapore.

Alterations in parietal and temporal white matter microstructure derived from diffusion tensor imaging occur in preclinical and clinical Alzheimer's disease. Amyloid beta (Aβ) deposition and such white matter alterations are two pathological hallmarks of Alzheimer's disease. However, the relationship between these pathologies is not yet understood, partly since conventional diffusion MRI methods cannot distinguish between cellular and extracellular processes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24507DOI Listing
January 2019

MR-PET head motion correction based on co-registration of multicontrast MR images.

Hum Brain Mapp 2019 Jan 3. Epub 2019 Jan 3.

Monash Biomedical Imaging, Monash University, Melbourne, Australia.

Head motion is a major source of image artefacts in neuroimaging studies and can lead to degradation of the quantitative accuracy of reconstructed PET images. Simultaneous magnetic resonance-positron emission tomography (MR-PET) makes it possible to estimate head motion information from high-resolution MR images and then correct motion artefacts in PET images. In this article, we introduce a fully automated PET motion correction method, MR-guided MAF, based on the co-registration of multicontrast MR images. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24497DOI Listing
January 2019

Discovering heritable modes of MEG spectral power.

Hum Brain Mapp 2019 Jan 1. Epub 2019 Jan 1.

Department of Computer Science, Helsinki Institute for Information Technology HIIT, Aalto University, Helsinki, Finland.

Brain structure and many brain functions are known to be genetically controlled, but direct links between neuroimaging measures and their underlying cellular-level determinants remain largely undiscovered. Here, we adopt a novel computational method for examining potential similarities in high-dimensional brain imaging data between siblings. We examine oscillatory brain activity measured with magnetoencephalography (MEG) in 201 healthy siblings and apply Bayesian reduced-rank regression to extract a low-dimensional representation of familial features in the participants' spectral power structure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24454DOI Listing
January 2019
1 Read

Critical role of glutamatergic and GABAergic neurotransmission in the central mechanisms of theta-burst stimulation.

Hum Brain Mapp 2019 Jan 1. Epub 2019 Jan 1.

Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.

Theta-burst stimulation (TBS) is a varied form of repetitive transcranial magnetic stimulation (rTMS) and has more rapid and powerful effects than rTMS. Experiments on the human motor cortex have demonstrated that intermittent TBS has facilitatory effects, whereas continuous TBS has inhibitory effects. Huang's simplified model provides a solid basis for elucidating such after-effects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24485DOI Listing
January 2019
1 Read

Where is the "where" in the brain? A meta-analysis of neuroimaging studies on spatial cognition.

Hum Brain Mapp 2019 Jan 1. Epub 2019 Jan 1.

Department of General Psychology, University of Padua, Padua, Italy.

Spatial representations are processed in the service of several different cognitive functions. The present study capitalizes on the Activation Likelihood Estimation (ALE) method of meta-analysis to identify: (a) the shared neural activations among spatial functions to reveal the "core" network of spatial processing; (b) the specific neural activations associated with each of these functions. Following PRISMA guidelines, a total of 133 fMRI and PET studies were included in the meta-analysis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24496DOI Listing
January 2019

Transforming brain signals related to value evaluation and self-control into behavioral choices.

Hum Brain Mapp 2019 Mar 28;40(4):1049-1061. Epub 2018 Dec 28.

Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science & Technology of China, Hefei, China.

The processes involved in value evaluation and self-control are critical when making behavioral choices. However, the evidence linking these two types of processes to behavioral choices in intertemporal decision-making remains elusive. As the ventromedial prefrontal cortex (vmPFC), striatum, and dorsolateral prefrontal cortex (dlPFC) have been associated with these two processes, we focused on these three regions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24379DOI Listing
March 2019
2 Reads
5.969 Impact Factor

A combined diffusion-weighted and electroencephalography study on age-related differences in connectivity in the motor network during bimanual performance.

Hum Brain Mapp 2018 Dec 26. Epub 2018 Dec 26.

Amsterdam Movement Science Institute (AMS) and Institute for Brain and Behaviour Amsterdam (iBBA), Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, The Netherlands.

We studied the relationship between age-related differences in inter- and intra-hemispheric structural and functional connectivity in the bilateral motor network. Our focus was on the correlation between connectivity and declined motor performance in older adults. Structural and functional connectivity were estimated using diffusion weighted imaging and resting-state electro-encephalography, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24491DOI Listing
December 2018

Spatial dynamics within and between brain functional domains: A hierarchical approach to study time-varying brain function.

Hum Brain Mapp 2018 Dec 26. Epub 2018 Dec 26.

The Mind Research Network, Albuquerque, New Mexico.

The analysis of time-varying activity and connectivity patterns (i.e., the chronnectome) using resting-state magnetic resonance imaging has become an important part of ongoing neuroscience discussions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24505DOI Listing
December 2018
2 Reads
5.969 Impact Factor

White matter during concussion recovery: Comparing diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI).

Hum Brain Mapp 2018 Dec 26. Epub 2018 Dec 26.

Neuroscience Research Program, St. Michael's Hospital, Toronto, Ontario, Canada.

Concussion pathophysiology in humans remains incompletely understood. Diffusion tensor imaging (DTI) has identified microstructural abnormalities in otherwise normal appearing brain tissue, using measures of fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD). The results of prior DTI studies suggest that acute alterations in microstructure persist beyond medical clearance to return to play (RTP), but these measures lack specificity. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.24500
Publisher Site
http://dx.doi.org/10.1002/hbm.24500DOI Listing
December 2018
11 Reads

Acute tryptophan loading decreases functional connectivity between the default mode network and emotion-related brain regions.

Hum Brain Mapp 2018 Dec 25. Epub 2018 Dec 25.

Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany.

It has been shown that the functional architecture of the default mode network (DMN) can be affected by serotonergic challenges and these effects may provide insights on the neurobiological bases of depressive symptomatology. To deepen our understanding of this possible interplay, we used a double-blind, randomized, cross-over design, with a control condition and two interventions to decrease (tryptophan depletion) and increase (tryptophan loading) brain serotonin synthesis. Resting-state fMRI from 85 healthy subjects was acquired for all conditions 3 hr after the ingestion of an amino acid mixture containing different amounts of tryptophan, the dietary precursor of serotonin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24494DOI Listing
December 2018
2 Reads

Developmental changes in functional brain networks from birth through adolescence.

Hum Brain Mapp 2018 Dec 23. Epub 2018 Dec 23.

Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Investigation of the brain connectome using functional magnetic resonance imaging (fMRI) and measures derived from graph theory analysis has emerged as a new approach to study brain development, cognitive function, and neurophysiological disorders. Here we use graph theory analysis to examine the influence of age, sex, and neurocognitive measures on developmental changes to the global and regional topology of functional brain networks derived from fMRI data recorded in 189 healthy subjects from the age of 0-18 years during rest. We observed that Global Efficiency and Rich-Club coefficient increased with age and Local Efficiency and Small-Worldness decreased with age, while Modularity at the global level showed an inverted U-shaped trajectory during development. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24457DOI Listing
December 2018

fMRI evidence of aberrant neural adaptation for objects in schizophrenia and bipolar disorder.

Hum Brain Mapp 2018 Dec 21. Epub 2018 Dec 21.

Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California.

Functional magnetic resonance imaging (fMRI) adaptation (also known as fMRI repetition suppression) has been widely used to characterize stimulus selectivity in vivo, a fundamental feature of neuronal processing in the brain. We investigated whether SZ patients and BD patients show aberrant fMRI adaptation for object perception. About 52 SZ patients, 55 BD patients, and 53 community controls completed an object discrimination task with three conditions: the same object presented twice, two exemplars from the same category, and two exemplars from different categories. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24472DOI Listing
December 2018

Distinct roles of brain activity and somatotopic representation in pathophysiology of focal dystonia.

Hum Brain Mapp 2018 Dec 20. Epub 2018 Dec 20.

Department of Advanced Neuroimaging, Integrative Brain Imaging Center (IBIC), National Center of Neurology and Psychiatry, Tokyo, Japan.

Two main neural mechanisms including loss of cortical inhibition and maladaptive plasticity have been thought to be involved in the pathophysiology of focal task-specific dystonia. Such loss of inhibition and maladaptive plasticity likely correspond to cortical overactivity and disorganized somatotopy, respectively. However, the most plausible mechanism of focal task-specific dystonia remains unclear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24486DOI Listing
December 2018