2,182 results match your criteria Human Bite Infections


Lyme neuroborreliosis in children: Report of nine cases and a review of the literature.

Arch Pediatr 2019 Mar 15. Epub 2019 Mar 15.

Service de microbiologie, hôpital Necker-enfants-malades, Assistance publique-hôpitaux de Paris, 149, rue de Sèvres, 75015 Paris, France.

Lyme neuroborreliosis is a bacterial infection caused by the dissemination and proliferation of a Borrelia species in the central nervous system. Neuroborreliosis occurs after transmission of the pathogen from an infected tick to a human host during a tick bite. We report nine cases of pediatric neuroborreliosis collected by the National Observatory of Pediatric Bacterial Meningitis in France between 2001 and 2012. Read More

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http://dx.doi.org/10.1016/j.arcped.2019.02.010DOI Listing

Down-selecting circumsporozoite protein-based malaria vaccine: a comparison of malaria sporozoite challenge model.

Parasite Immunol 2019 Mar 18:e12624. Epub 2019 Mar 18.

Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kakuma-machi, Kanazawa, 920-1192, Japan.

Plasmodium falciparum circumsporozoite protein (PfCSP) is the main target antigen in development of pre-erythrocytic malaria vaccines. To evaluate PfCSP vaccines in animal models, challenge by intravenous sporozoite injection is preferentially used. However, in clinical trials, vaccinated human volunteers are exposed to the bites of malaria-infected mosquitoes. Read More

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http://dx.doi.org/10.1111/pim.12624DOI Listing

Determinants of health seeking behavior of animal bite victims in rabies endemic South Bhutan: a community-based contact-tracing survey.

BMC Public Health 2019 Feb 27;19(1):237. Epub 2019 Feb 27.

Zoonosis Program, Department of Public Health, Ministry of Health, Thimphu, Bhutan.

Background: Dog bites are the main source of rabies infection and death in humans, contributing up to 99% of all cases. We conducted a contact-tracing study to evaluate the health seeking and treatment compliance behaviors of people following potential exposure to rabies in rabies endemic south Bhutan.

Methods: Using information from the rabies post exposure prophylaxis (PEP) register, animal-exposed victims who had visited five hospitals in south Bhutan between January and March 2017 were traced and further data were collected from them using a structured questionnaire. Read More

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http://dx.doi.org/10.1186/s12889-019-6559-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391763PMC
February 2019
2 Reads

Breastfeeding in the time of Zika: a systematic literature review.

PeerJ 2019 19;7:e6452. Epub 2019 Feb 19.

Instituto de Salud Pública, Universidad Veracruzana, Xalapa, Veracruz, México.

Background: The disease Zika is considered as emergent. The infection can be acquired through different routes: a bite from the mosquito, sexual contact, from mother to child during pregnancy and by blood transfusion. The possibility of Zika transmission through human lactation has been considered. Read More

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http://dx.doi.org/10.7717/peerj.6452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385688PMC
February 2019
1 Read

Emerging Viral Infections Causing Anterior Uveitis.

Ocul Immunol Inflamm 2019 Feb 22:1-10. Epub 2019 Feb 22.

d Department of Ophthalmology , California Pacific Medical Center , San Francisco , CA , USA.

Purpose: To review the systemic and ocular manifestations of specific emergent viral infectious diseases relevant to the ophthalmologist with particular emphasis on anterior uveitis Methods: Review of literature.

Results: Arboviral diseases are among the most important emergent and resurgent human infections, occurring mostly in tropical and subtropical zones, but appearing in virtually all regions of the world as a result of climate change, travel, and globalization. Arboviral infections are transmitted to humans by the bite of hematophagous arthropods, mainly mosquitoes. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1562080DOI Listing
February 2019
2 Reads

wound infection transmitted by a pet dog.

Germs 2018 Dec 3;8(4):214-217. Epub 2018 Dec 3.

PhD, Laboratory of Clinical Microbiology and Molecular Microbiology, School of Medicine, University of Crete, 70013 Heraklion, Crete, Greece.

Introduction: Human pasteurellosis is a severe human infection that accounts for 20-30 human deaths annually worldwide. Mucous secretions derived from pets comprise the primary source of infection, which are transmitted through animal scratches or bites.

Case Report: We describe a case of wound infection in an immunocompetent adult with a decubitus ulcer of the lower extremity. Read More

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http://dx.doi.org/10.18683/germs.2018.1149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363398PMC
December 2018

High malaria transmission sustained by s.l. occurring both indoors and outdoors in the city of Yaoundé, Cameroon.

Wellcome Open Res 2018 23;3:164. Epub 2018 Dec 23.

Malaria Research Laboratory, OCEAC, Yaoundé, Cameroon.

Malaria remains a major public health problem in Cameroon; however, despite reports on the adaptation of anopheline species to urban habitats, there is still not enough information on malaria transmission pattern in urban settings. In the frame of a larval control trial in the city of Yaoundé, we conducted baseline surveys to assess malaria transmission dynamics in this city. Adult mosquitoes were collected indoors and outdoors using CDC light traps and human landing catches from March 2017 to March 2018 in 30 districts of Yaoundé, Cameroon. Read More

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http://dx.doi.org/10.12688/wellcomeopenres.14963.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364383PMC
December 2018

Feasibility of feeding Aedes aegypti mosquitoes on dengue virus-infected human volunteers for vector competence studies in Iquitos, Peru.

PLoS Negl Trop Dis 2019 02 12;13(2):e0007116. Epub 2019 Feb 12.

Department of Entomology and Nematology, University of California, Davis, Davis, California, United States of America.

Background: Transmission of dengue virus (DENV) from humans to mosquitoes represents a critical component of dengue epidemiology. Examinations of this process have generally been hampered by a lack of methods that adequately represent natural acquisition of DENV by mosquitoes from humans. In this study, we assessed artificial and natural blood feeding methods based on rates of DENV infection and dissemination within mosquitoes for use in a field-based epidemiological cohort study in Iquitos, Peru. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388938PMC
February 2019
4 Reads

Developments in human rabies prophylaxis.

Authors:
M J Warrell

Rev Sci Tech 2018 Aug;37(2):629-647

Rabies is entirely preventable. All deaths are the result of failed prophylaxis. Rabies encephalomyelitis has never been reported in anyone who received both pre-exposure vaccination and a post-exposure booster. Read More

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http://doc.oie.int/dyn/portal/index.seam?page=alo&aloId=
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http://dx.doi.org/10.20506/rst.37.2.2829DOI Listing
August 2018
6 Reads

Human Tick-Borne Diseases in Australia.

Front Cell Infect Microbiol 2019 28;9. Epub 2019 Jan 28.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

There are 17 human-biting ticks known in Australia. The bites of , and can cause paralysis, inflammation, and severe local and systemic reactions in humans, respectively. Six ticks, including , and may transmit , or subsp. Read More

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http://dx.doi.org/10.3389/fcimb.2019.00003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360175PMC
January 2019
3 Reads

Acceptability of Aedes aegypti blood feeding on dengue virus-infected human volunteers for vector competence studies in Iquitos, Peru.

PLoS Negl Trop Dis 2019 02 11;13(2):e0007090. Epub 2019 Feb 11.

Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America.

As part of a study to investigate drivers of dengue virus (DENV) transmission dynamics, this qualitative study explored whether DENV-infected residents of Iquitos, Peru, considered it acceptable (1) to participate in direct mosquito feeding experiments (lab-reared Aedes aegypti mosquitoes fed directly on human volunteers) and (2) to provide blood meals indirectly (Ae. aegypti fed on blood drawn from participants by venipuncture). Twelve focus group discussions (FGDs; 94 participants: 82 females and 12 males) were conducted in January 2014 to explore six themes: (1) concerns and preferences regarding direct mosquito feeds and blood draws, (2) comprehension of and misconceptions about study procedures, (3) motivating factors for participation, (4) acceptability of children's participation, (5) willingness to provide multiple samples over several days, and (6) preference for direct feedings in homes versus the study laboratory. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386403PMC
February 2019
1 Read

Bats and Viruses: Emergence of Novel Lyssaviruses and Association of Bats with Viral Zoonoses in the EU.

Trop Med Infect Dis 2019 Feb 7;4(1). Epub 2019 Feb 7.

Wildlife Zoonoses and Vector-borne Diseases Research Group, Animal and Plant Health Agency (APHA), KT15 3NB Weybridge-London, UK.

Bats in the EU have been associated with several zoonotic viral pathogens of significance to both human and animal health. Virus discovery continues to expand the existing understating of virus classification, and the increased interest in bats globally as reservoirs or carriers of zoonotic agents has fuelled the continued detection and characterisation of new lyssaviruses and other viral zoonoses. Although the transmission of lyssaviruses from bat species to humans or terrestrial species appears rare, interest in these viruses remains, through their ability to cause the invariably fatal encephalitis-rabies. Read More

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http://dx.doi.org/10.3390/tropicalmed4010031DOI Listing
February 2019
6 Reads

[Lyme nephritis in humans: Physio-pathological bases and spectrum of kidney lesions].

Nephrol Ther 2019 Jan 31. Epub 2019 Jan 31.

Service de néphrologie-dialyse, centre hospitalier de Cahors, 335, rue du président-Wilson, 46000 Cahors, France; Département de néphrologie et transplantation d'organes, CHU Rangueil, 1, avenue du Professeur-Jean-Poulhès, 31400 Toulouse, France; Inserm U563, IFR-BMT, CHU Purpan, 105, avenue de Cassalardit, 31300 Toulouse, France; Université Paul Sabatier, route de Narbonne, 31330 Toulouse, France.

Known in less than half a century, borreliosis, or Lyme disease, is a zoonosis caused by the tick bite. It is the most common vector disease in Europe and the United States. Borrelia burgdorferi sensu lato, the bacterium in question, is fitted with a "cunning device" that allows it to trick the immune system and implant the infection chronically. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17697255183065
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http://dx.doi.org/10.1016/j.nephro.2018.09.004DOI Listing
January 2019
9 Reads

Cutaneous Leishmaniasis: Updates in Diagnosis and Management.

Infect Dis Clin North Am 2019 Mar;33(1):101-117

U.S. Naval Medical Research Unit Number 6, Lima, Peru.

Cutaneous leishmaniasis (CL) is a diverse human disease caused by more than 20 Leishmania species transmitted by the bite of an infected sand fly. Diagnostic testing is recommended to confirm infection and determine the infecting species. Treatment decisions are complex and providers should consider infecting species, patient comorbidities, extent and location of lesions, and previous treatments. Read More

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http://dx.doi.org/10.1016/j.idc.2018.10.004DOI Listing
March 2019
2 Reads

Dissecting Flavivirus Biology in Salivary Gland Cultures from Fed and Unfed (Black-Legged Tick).

MBio 2019 01 29;10(1). Epub 2019 Jan 29.

Biology of Vector-Borne Viruses Section, Laboratory of Virology, Rocky Mountain Laboratories, NIAID/NIH, Hamilton, Montana, USA.

The tick transmits a number of pathogens, including tick-borne flaviviruses (TBFVs). In the United States, confirmed human infections with the Powassan virus (POWV) TBFV have a fatality rate of ∼10% and are increasing in incidence. Tick salivary glands (SGs) serve as an organ barrier to TBFV transmission, and little is known regarding the location of TBFV infection in SGs from fed ticks. Read More

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http://dx.doi.org/10.1128/mBio.02628-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355982PMC
January 2019
2 Reads
6.786 Impact Factor

Wild banana [Ensete superbum (Roxb.) Cheesman.]: Ethnomedicinal, phytochemical and pharmacological overview.

J Ethnopharmacol 2019 Apr 25;233:218-233. Epub 2019 Jan 25.

National Innovation Foundation-India (Autonomous Body of Department of Science and Technology, Govt. of India), Grambharti, Amarapur, Gandhinagar, Gujarat 382650, India. Electronic address:

Ethnopharmacological Relevance: Ensete superbum (Roxb.) Cheesman. (Family: Musaceae), commonly known as "Wild Banana" is well recorded as popular ethnomedicine for medicinal and nutritional uses by different people and communities native to India, Ethiopia, Thailand, Myanmar and Vietnam. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183297
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http://dx.doi.org/10.1016/j.jep.2018.12.048DOI Listing
April 2019
5 Reads

The Controlled Human Malaria Infection Experience at the University of Maryland.

Am J Trop Med Hyg 2019 Mar;100(3):556-565

Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland.

Controlled human malaria infection (CHMI) is a powerful tool to evaluate the efficacy of malaria vaccines and pharmacologics. Investigators at the University of Maryland, Baltimore, Center for Vaccine Development (UMB-CVD) pioneered the technique in the 1970s and continue to advance the frontiers of CHMI research. We reviewed the records of 338 malaria-naive volunteers who underwent CHMI at UMB-CVD with from 1971 until 2017. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0476
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http://dx.doi.org/10.4269/ajtmh.18-0476DOI Listing
March 2019
12 Reads

Human Pasteurellosis Health Risk for Elderly Persons Living with Companion Animals.

Emerg Infect Dis 2019 Feb;25(2):229-235

The necessity for diagnosis and treatment of this infection is emphasized by the high number of complications and death rate. Read More

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http://dx.doi.org/10.3201/eid2502.180641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346445PMC
February 2019
1 Read

Five-year Audit of Infectious Diseases at a Tertiary Care Hospital in Karachi, Pakistan.

Cureus 2018 Nov 5;10(11):e3551. Epub 2018 Nov 5.

Miscellaneous, The Indus Hospital, Karachi, PAK.

Purpose To estimate the burden of infectious diseases and the seasonality of mosquito-borne diseases seen at The Indus Hospital, Karachi (TIH). Methodology We performed a retrospective data analysis of all infectious diseases (ID) cases, retrieved from medical records over a five-year period starting from 1 January 2012 till 31 December 2016 at The Indus Hospital (TIH), which is a 150-bed, charity-based, tertiary-care health facility. The collected data has been categorized into three groups: (A) public health-related diseases, including community and environmental IDs, i. Read More

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http://dx.doi.org/10.7759/cureus.3551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324853PMC
November 2018
5 Reads

Immunological responses to the relapsing fever spirochete in infected Rhesus macaques: implications for pathogenesis and diagnosis.

Infect Immun 2019 Jan 14. Epub 2019 Jan 14.

Department of Pediatrics, National School of Tropical Medicine, and Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas.

The global public health impact of relapsing fever (RF) spirochetosis is significant, as the pathogens exist on five of seven continents. The hallmark sign of infection is episodic fever and the greatest threat is to the unborn. With the goal of better understanding the specificity of B cell responses and the role of immune responses in pathogenicity, we infected Rhesus macaques with (a new world RF spirochete species) by tick bite and monitored the immune responses generated in response to the pathogen. Read More

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http://dx.doi.org/10.1128/IAI.00900-18DOI Listing
January 2019
3 Reads

Mosquito-borne epornitic flaviviruses: an update and review.

J Gen Virol 2019 Feb 22;100(2):119-132. Epub 2019 Jan 22.

1​FARAH Research Center, Department of Pathology, Faculty of Veterinary Medicine, University of Liège, Sart Tilman B43, B-4000 Liège, Belgium.

West Nile Virus, Usutu virus, Bagaza virus, Israel turkey encephalitis virus and Tembusu virus currently constitute the five flaviviruses transmitted by mosquito bites with a marked pathogenicity for birds. They have been identified as the causative agents of severe neurological symptoms, drop in egg production and/or mortalities among avian hosts. They have also recently shown an expansion of their geographic distribution and/or a rise in cases of human infection. Read More

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http://dx.doi.org/10.1099/jgv.0.001203DOI Listing
February 2019
4 Reads

Successful replantation of an amputated helical rim with microvascular anastomosis.

Arch Craniofac Surg 2018 Dec 27;19(4):304-308. Epub 2018 Dec 27.

Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.

Replantation using microvascular anastomosis is considered to be the optimal method in treating the amputated ear in terms of resulting color, texture, and shape. Only a few cases of ear replantation have been reported because it is anatomically difficult to identify suitable vessels for anastomosis. We successfully replanted the amputated helical rim of the ear using single arterial anastomosis. Read More

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http://dx.doi.org/10.7181/acfs.2018.02173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325333PMC
December 2018
1 Read

Host-feeding patterns of Culex mosquitoes in Iran.

Parasit Vectors 2018 Dec 27;11(1):669. Epub 2018 Dec 27.

Bernhard Nocht Institute for Tropical Medicine, WHO Collaborating Centre for Arbovirus and Hemorrhagic Fever Reference and Research, Hamburg, Germany.

Background: Different mosquito-borne pathogens are circulating in Iran including Sindbis virus, West Nile virus, filarioid worms and malaria parasites. However, the local transmission cycles of these pathogenic agents are poorly understood, especially because ecological data on vector species are scarce and there is limited knowledge about the host range; this understanding could help to direct species-specific vector control measurements or to prioritize research.

Methods: In the summers of 2015 and 2016, blood-fed mosquitoes were collected at 13 trapping sites on the coast of the Caspian Sea in northern Iran and at an additional trapping site in western Iran. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3237-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307250PMC
December 2018
8 Reads

Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts.

Cell Microbiol 2019 Feb 7;21(2):e12998. Epub 2019 Jan 7.

Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY, USA.

Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States and Europe. The spirochetes are transmitted from mammalian and avian reservoir hosts to humans via ticks. Following tick bites, spirochetes colonize the host skin and then disseminate haematogenously to various organs, a process that requires this pathogen to evade host complement, an innate immune defence system. Read More

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http://doi.wiley.com/10.1111/cmi.12998
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http://dx.doi.org/10.1111/cmi.12998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336514PMC
February 2019
11 Reads

Mosquito Bite-Induced Controlled Human Malaria Infection with Plasmodium vivax or P. falciparum Generates Immune Responses to Homologous and Heterologous Preerythrocytic and Erythrocytic Antigens.

Infect Immun 2019 Mar 21;87(3). Epub 2019 Feb 21.

Malaria Vaccine Branch, U.S. Military Malaria Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

Seroepidemiological studies on the prevalence of antibodies to malaria antigens are primarily conducted on individuals from regions of endemicity. It is therefore difficult to accurately correlate the antibody responses to the timing and number of prior malaria infections. This study was undertaken to assess the evolution of antibodies to the dominant surface antigens of and following controlled human malaria infection (CHMI) in malaria-naive individuals. Read More

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http://iai.asm.org/lookup/doi/10.1128/IAI.00541-18
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http://dx.doi.org/10.1128/IAI.00541-18DOI Listing
March 2019
4 Reads
3.731 Impact Factor

Human tularaemia associated with exposure to domestic dogs-United States, 2006-2016.

Zoonoses Public Health 2018 Dec 16. Epub 2018 Dec 16.

Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado.

Dogs have been implicated in the zoonotic transmission of numerous pathogens. Whereas cats are known to transmit Francisella tularensis to humans via bite and other routes, the role of dogs in facilitating infection is much less understood. We reviewed tularaemia case investigation records collected through national surveillance during 2006-2016 to summarize those with dog involvement, characterize the nature of dog-related exposure and describe associated clinical characteristics. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/zph.12552
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http://dx.doi.org/10.1111/zph.12552DOI Listing
December 2018
11 Reads

Challenging diagnosis of congenital malaria in non-endemic areas.

Malar J 2018 Dec 14;17(1):470. Epub 2018 Dec 14.

Unit of Parasitology, Bambino Gesù Children's Hospital, Piazza Sant'Onofrio 4, 00165, Rome, Italy.

Background: Congenital malaria is usually defined as the detection of asexual forms of Plasmodium spp. in a blood sample of a neonate during perinatal age if there is no possibility of postpartum infection by a mosquito bite. The incidence of congenital malaria is highly variable and seems related to several factors, such as different diagnostic methods for Plasmodium spp. Read More

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http://dx.doi.org/10.1186/s12936-018-2614-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295090PMC
December 2018
1 Read

Saliva Induces Heme Oxygenase-1 Expression at Bite Sites.

Front Immunol 2018 28;9:2779. Epub 2018 Nov 28.

Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.

Sand flies bite mammalian hosts to obtain a blood meal, driving changes in the host inflammatory response that support the establishment of infection. This effect is partially attributed to components of sand fly saliva, which are able to recruit and activate leukocytes. Our group has shown that heme oxygenase-1 (HO-1) favors survival in infected cells by reducing inflammatory responses. Read More

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http://dx.doi.org/10.3389/fimmu.2018.02779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279893PMC
November 2018
2 Reads

Identification and characterization of the causative triatomine bugs of anaphylactic shock in Zhanjiang, China.

Infect Dis Poverty 2018 Dec 11;7(1):127. Epub 2018 Dec 11.

Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.

Background: Two health concerns primarily related to triatomine bugs are transmission of Trypanosoma cruzi through infective feces, and allergic reactions induced by triatomine bites. In the Southwestern United States, reduviid bugs bites commonly cause insect allergy. In South China, four cases of anaphylactic shock have been reported after this bite exposure. Read More

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http://dx.doi.org/10.1186/s40249-018-0509-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291942PMC
December 2018

West Nile virus in Algeria: a comprehensive overview.

New Microbes New Infect 2019 Jan 21;27:9-13. Epub 2018 Oct 21.

UMR VITROME, Aix-Marseille Université, IRD, Service de Santé des Armées, Assistance Publique-Hôpitaux de Marseille, IHU Méditerranée-Infection, Marseille, France.

West Nile virus (WNV) is a mosquito-borne virus belonging to the genus related to the Japanese encephalitis antigenic complex of family. It is transmitted by the bite of infected mosquitoes. The virus is maintained in a mosquito-bird-mosquito transmission cycle. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S20522975183009
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http://dx.doi.org/10.1016/j.nmni.2018.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260397PMC
January 2019
11 Reads

Fournier's Gangrene of the Penis following a Human Bite Wound.

Case Rep Urol 2018 25;2018:9798607. Epub 2018 Oct 25.

West Virginia University Department of Urology, USA.

Fournier's gangrene isolated to the penis is exceedingly rare. It is an urologic emergency that requires emergent parenteral antibiotics as well as aggressive irrigation and debridement. While human bite wounds can be overlooked as a serious cause of injury and infection, they can result in highly dangerous, polymicrobial infections in affected patients. Read More

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http://dx.doi.org/10.1155/2018/9798607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222233PMC
October 2018

Antibiotic resistant zoonotic bacteria in Irrawaddy squirrel (Callosciurus pygerythrus).

Vet Med Sci 2018 Nov 29. Epub 2018 Nov 29.

Department of Microbiology and Veterinary Public Health, Chittagong Veterinary and Animal Sciences University (CVASU), Chittagong, Bangladesh.

Irrawaddy squirrel (Callosciurus pygerythrus) may play an important role in the transmission of zoonotic bacteria, but little is known about the carriage of zoonotic bacteria in this common frugivorous rodent in Bangladesh. We aimed to investigate the presence of common zoonotic bacterial pathogens in Irrawaddy squirrel in the southeast part of Bangladesh. A total of 27 rectal and 27 oro-nasal swabs were collected from 27 healthy wild Irrawaddy squirrels. Read More

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http://dx.doi.org/10.1002/vms3.138DOI Listing
November 2018
11 Reads

A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells.

Sci Rep 2018 Nov 28;8(1):17453. Epub 2018 Nov 28.

Children's Cancer Research Institute, Vienna, Austria.

Bispecific T cell engager (BiTE) antibody constructs are successfully used as cancer therapeutics. We hypothesized that this treatment strategy could also be applicable for therapy of human cytomegalovirus (HCMV) infection, since HCMV-encoded proteins are abundantly expressed on the surface of infected cells. Here we show that a BiTE antibody construct directed against HCMV glycoprotein B (gB) and CD3 efficiently triggers T cells to secrete IFN-γ and TNF upon co-culture with fibroblasts infected with HCMV strain AD169, Towne or Toledo. Read More

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http://www.nature.com/articles/s41598-018-36055-2
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http://dx.doi.org/10.1038/s41598-018-36055-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261951PMC
November 2018
10 Reads

Epstein-Barr virus and skin.

An Bras Dermatol 2018 Nov/Dec;93(6):786-799

Hospital Cayetano Heredia, Lima, Peru.

Epstein-Barr virus is a DNA virus infecting human beings and could affect 90% of human population. It is crucial to take in account that in Latin America, unlike what happens in developed countries, the exposure to the virus is very early and therefore people have a much longer interaction with the virus. The virus is related to many diseases, mainly the oncological ones, and when the onset is in cutaneous tissue, it can present many clinical variants, as well acute as chronic ones. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20187021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256212PMC
February 2019
10 Reads

Exposure history, post-exposure prophylaxis use, and clinical characteristics of human rabies cases in China, 2006-2012.

Sci Rep 2018 Nov 21;8(1):17188. Epub 2018 Nov 21.

Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Rabies is still a public health threat in China. Evaluating the exposure history, clinical characteristics, and post-exposure prophylaxis (PEP) of the cases could help in identifying approaches to reducing the number of these preventable deaths. We analysed data collected from 10,971 case-investigations conducted in China from 2006 to 2012. Read More

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http://dx.doi.org/10.1038/s41598-018-35158-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249250PMC
November 2018
2 Reads

Capnocytophaga canimorsus Capsular Serovar and Disease Severity, Helsinki Hospital District, Finland, 2000-2017.

Emerg Infect Dis 2018 12;24(12):2195-2201

We assembled a collection of 73 Capnocytophaga canimorsus isolates obtained from blood cultures taken from patients treated at Helsinki University Hospital (Helsinki, Finland) during 2000-2017. We serotyped these isolates by PCR and Western blot and attempted to correlate pathogen serovar with patient characteristics. Our analyses showed, in agreement with previous research, that 3 C. Read More

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http://dx.doi.org/10.3201/eid2412.172060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256374PMC
December 2018
1 Read

Knowledge, attitudes and practices towards dog-bite related rabies in para-medical staff at rural primary health centres in Baramati, western India.

PLoS One 2018 16;13(11):e0207025. Epub 2018 Nov 16.

College of Veterinary Medicine, School of Veterinary and Life Sciences, Murdoch University, Western Australia, Australia.

The lack of awareness regarding rabies amongst rural primary care health staff and their adverse practices towards the management of dog-bite wounds is a major contributor to the high incidence of rabies infection and subsequent human mortality in India. A Knowledge, Attitudes and Practices survey was carried out involving 54 nursing and non-nursing staff working in 18 rural Primary Health centres and sub-centres around Baramati town of Pune district in Western India. Multivariable logistic regression models were constructed to assess factors that influenced knowledge of rabies and practices towards management of dog-bite related wounds. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207025PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239288PMC
November 2018

Avoiding bites and scratches? Understanding the public health implication of human-bat interactions in Ghana.

Zoonoses Public Health 2019 02 14;66(1):108-116. Epub 2018 Nov 14.

Centre for African Wetlands, University of Ghana, Accra, Ghana.

Zoonotic pathogens cause an estimated 70% of emerging and re-emerging infectious diseases in humans, affecting various aspects of human development on a global scale. The significance of bats as a source of emerging infectious diseases is being progressively appreciated. This study was undertaken post-Ebola virus disease in West Africa and assessed the public health implications of human-bat interactions by exploring the reasons for contact between humans and bats, as well as reported actions taken upon experiencing bat bites or scratches. Read More

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http://doi.wiley.com/10.1111/zph.12540
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http://dx.doi.org/10.1111/zph.12540DOI Listing
February 2019
15 Reads

Human rabies control in Lebanon: a call for action.

Epidemiol Infect 2018 Nov 15:1-8. Epub 2018 Nov 15.

Department of Internal Medicine,Division of Infectious Diseases, American University of Beirut Medical Center,Beirut,Lebanon.

The status of rabies as a neglected disease has made its eradication rather challenging in different parts of the world despite the availability of a successful vaccine. Lebanon, in particular, is a country endemic to the disease with several cases of rabies deaths reported over the past 30 years. The risk of rabies, however, has taken a new turn over the past few years in Lebanon with two emerging situations that have made the control of the disease rather challenging: the neighbouring Syrian war and the local garbage crisis. Read More

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http://dx.doi.org/10.1017/S095026881800300XDOI Listing
November 2018
2 Reads

[Dirofilariasis in the head and neck region. Case report].

Orv Hetil 2018 11;159(45):1844-1847

Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Szigony u. 36., 1083.

Dirofilariasis refers to an infection caused by a specific parasitic roundworm. Dirofilaria repens - transmitted by mosquito bites - accounts for most human cases. The parasite forms a subcutaneous mass called cutaneous dirofilariasis near the original site of intrusion. Read More

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https://www.akademiai.com/doi/10.1556/650.2018.31216
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http://dx.doi.org/10.1556/650.2018.31216DOI Listing
November 2018
14 Reads

Ante-mortem Diagnosis of Human Rabies Cases Using SYBR Green Real-Time PCR.

Arch Iran Med 2018 Oct 1;21(10):473-477. Epub 2018 Oct 1.

Virology Department, Pasteur Institute of Iran, Tehran, Iran.

Background: Rabies, as the most important zoonotic disease, is transmitted through a bite or scratch by an infected domestic or wild carnivores and bats or contact of open wound with infected saliva. The fluorescent antibody test (FAT) is the "gold standard" diagnostic method for suspected brain samples. For close monitoring of unknown encephalitis, rabies surveillance, and also the limitations for post-mortem diagnosis of rabies in human and performing fast prophylactic measures for other individuals in contact with rabid patients, ante-mortem diagnosis based on molecular methods such as real-time polymerase chain reaction (PCR) seems to be more reliable. Read More

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October 2018
14 Reads
1.110 Impact Factor

Proteome characterization in various biological fluids of Trypanosoma brucei gambiense-infected subjects.

J Proteomics 2019 Mar 7;196:150-161. Epub 2018 Nov 7.

Institute of Neuroepidemiology and Tropical Neurology, School of Medicine, CNRS FR 3503 GEIST, University of Limoges, INSERM UMR 1094 Tropical Neuroepidemiology, Limoges, France. Electronic address:

Human African trypanosomiasis (HAT) is a neglected tropical disease that is endemic in sub-Saharan Africa. Control of the disease has been recently improved by better screening and treatment strategies, and the disease is on the WHO list of possible elimination. However, some physiopathological aspects of the disease transmission and progression remain unclear. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18743919183039
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http://dx.doi.org/10.1016/j.jprot.2018.11.005DOI Listing
March 2019
14 Reads

Extensive Diversity of RNA Viruses in Australian Ticks.

J Virol 2019 Feb 17;93(3). Epub 2019 Jan 17.

Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, Australia

Understanding the microbiome of ticks in Australia is of considerable interest given the ongoing debate over whether Lyme disease and its causative agent, the bacterium , are present in Australia. The diversity of bacteria infecting Australian ticks has been studied using both culture- and metagenomics-based techniques. However, little is known about the virome of Australian ticks, including whether this includes viruses with the potential to infect mammals. Read More

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http://jvi.asm.org/lookup/doi/10.1128/JVI.01358-18
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http://dx.doi.org/10.1128/JVI.01358-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340049PMC
February 2019
14 Reads

Prophylactic Antibiotics Are Not Needed Following Rattlesnake Bites.

Am J Med 2018 Nov 4;131(11):1367-1371. Epub 2018 Jul 4.

Division of Infectious Diseases, Department of Medicine. Electronic address:

Background: Antibiotics are sometimes administered to victims of rattlesnake bites in the hope of preventing infections. Experts in the field recommend that prophylactic antibiotics not be used because secondary infections are rare. Current recommendations are based on a small number of studies conducted in the United States. Read More

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http://dx.doi.org/10.1016/j.amjmed.2018.06.006DOI Listing
November 2018
2 Reads

High seroprevalence of Babesia antibodies among Borrelia burgdorferi-infected humans in Sweden.

Ticks Tick Borne Dis 2019 01 28;10(1):186-190. Epub 2018 Oct 28.

Department of Laboratory Medicine, Lund University, Skåne University Hospital, Lund, Sweden. Electronic address:

In northern Europe, tick-borne diseases such as Lyme borreliosis (LB) and tick-borne encephalitis (TBE) are well known. The actual incidence of Babesia infections, however, has remained elusive. In this study, the prevalence of antibodies against two Babesia spp. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.10.007DOI Listing
January 2019
2 Reads

Outdoor malaria transmission risks and social life: a qualitative study in South-Eastern Tanzania.

Malar J 2018 Oct 29;17(1):397. Epub 2018 Oct 29.

Environmental Health and Ecological Sciences Department, Ifakara Health Institute, Kiko Avenue, Mikocheni, PO Box 78373, Dar es Salaam, United Republic of Tanzania.

Background: Behaviour changes in mosquitoes from indoor to outdoor biting result in continuing risk of malaria from outdoor activities, including routine household activities and occasional social and cultural practices and gatherings. This study aimed to identify the range of social and cultural gatherings conducted outdoors and their associated risks for mosquito bites.

Methods: A cross-sectional study was conducted in four villages in the Kilombero Valley from November 2015 to March 2016. Read More

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https://malariajournal.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12936-018-2550-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206631PMC
October 2018
6 Reads

First whole genome sequencing of Russian isolate of Capnocytophaga canimorsus, opportunistic pathogen causing lethal sepsis.

Microb Pathog 2018 Dec 18;125:493-496. Epub 2018 Oct 18.

Central Research Institute of Epidemiology, Novogireevskaya str. 3a, Moscow, 111123, Russia. Electronic address:

Capnocytophaga canimorsus is a part of healthy oral flora of dogs and cats. However, when it is transmitted to human subjects via animal bites or scratches, it can cause severe complications like endocarditis or even lethal septic shock, especially in immunocompromised persons. In this study, we performed the first whole-genome sequencing on Illumina HiSeq platform of Russian isolate of C. Read More

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http://dx.doi.org/10.1016/j.micpath.2018.10.020DOI Listing
December 2018
2 Reads

Vector bionomics and malaria transmission in an area of sympatry of An. arabiensis, An. coluzzii and An. gambiae.

Acta Trop 2019 Jan 16;189:129-136. Epub 2018 Oct 16.

Unité d'entomologie médicale, Institut Pasteur de Dakar, BP 220, Dakar, Senegal. Electronic address:

Despite extensive genetic studies on their variability and differentiation, few is known about the specific and relative role of An. coluzzii, An. gambiae and An. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.10.005DOI Listing
January 2019
3 Reads

A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages.

Malar J 2018 Oct 17;17(1):370. Epub 2018 Oct 17.

Center for Infectious Disease Research, Seattle, WA, USA.

Background: Plasmodium vivax is the most geographically widespread of the human malaria parasites, causing 50,000 to 100,000 deaths annually. Plasmodium vivax parasites have the unique feature of forming dormant liver stages (hypnozoites) that can reactivate weeks or months after a parasite-infected mosquito bite, leading to new symptomatic blood stage infections. Efforts to eliminate P. Read More

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http://dx.doi.org/10.1186/s12936-018-2519-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192329PMC
October 2018
3 Reads

Current Status of Tick-Borne Diseases in South Korea.

Vector Borne Zoonotic Dis 2018 Oct 17. Epub 2018 Oct 17.

1 Department of Internal Medicine and Inha University School of Medicine , Incheon, Republic of Korea.

Background: Bites with tick-borne pathogens can cause various bacterial, viral, or parasitic diseases in humans. Tick-transmitted diseases are known as contributing factors to the increasing incidence and burden of diseases. The present article investigated the epidemiology of tick-borne diseases in South Korea. Read More

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http://dx.doi.org/10.1089/vbz.2018.2298DOI Listing
October 2018
4 Reads