536,509 results match your criteria Hospitals & health networks / AHA[Journal]


Preconception Care in the Veterans Health Administration.

Semin Reprod Med 2018 Nov 19;36(6):327-339. Epub 2019 Apr 19.

VA Central Office, Women's Health Services, Washington, District of Columbia.

Preconception care (PCC), defined as a set of interventions to help women optimize their health and well-being prior to pregnancy, can improve pregnancy outcomes and is recommended by national organizations including the Centers for Disease Control and Prevention and the American College of Obstetricians and Gynecologists. Women Veterans who use the Department of Veterans Affairs (VA) health care system may face elevated risks of adverse pregnancy and birth outcomes due to a high prevalence of chronic medical and mental health conditions as well as psychosocial stressors including sexual trauma history and intimate partner violence. Many women Veterans of childbearing age experience poverty and homelessness, which are key social determinants of poor reproductive health outcomes. Read More

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http://dx.doi.org/10.1055/s-0039-1678753DOI Listing
November 2018

Variation in hospital charges in patients with external ventricular drains: comparison between the intensive care and surgical floor settings.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

3Department of Neurosurgery, University of Washington School of Medicine, Seattle, Washington.

OBJECTIVEPlacement of an external ventricular drain (EVD) is a common and potentially life-saving neurosurgical procedure, but the economic aspect of EVD management and the relationship to medical expenditure remain poorly studied. Similarly, interinstitutional practice patterns vary significantly. Whereas some institutions require that patients with EVDs be monitored strictly within the intensive care unit (ICU), other institutions opt primarily for management of EVDs on the surgical floor. Read More

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https://thejns.org/view/journals/j-neurosurg-pediatr/aop/art
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http://dx.doi.org/10.3171/2019.2.PEDS18545DOI Listing
April 2019
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Intraoperative monitoring of olfactory function: a feasibility study.

J Neurosurg 2019 Apr 19:1-6. Epub 2019 Apr 19.

2Faculty of Medicine, University of Geneva, Switzerland.

OBJECTIVEIntraoperative neuromonitoring of the chemical senses (smell and taste) has never been performed. The objective of this study was to determine if olfactory-evoked potentials could be obtained intraoperatively under general anesthesia.METHODSA standard olfactometer was used in the surgical theater with hydrogen sulfide (4 ppm, 200 msec). Read More

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https://thejns.org/view/journals/j-neurosurg/aop/article-10.
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http://dx.doi.org/10.3171/2019.1.JNS182731DOI Listing
April 2019
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Cortisol suppression after memory reactivation impairs later memory performance.

Psychoneuroendocrinology 2019 Apr 9;106:226-232. Epub 2019 Apr 9.

Laboratory for Behavioral Neurology and Imaging of Condition, Department of Basic Neurosciences, University of Geneva, Switzerland; Center for the Interdisciplinary Study of Gerontology and Vulnerability (CIGEV), University of Geneva, Switzerland; Swiss National Center of Competences in Research LIVES - Overcoming vulnerabilities: life course perspective, Lausanne and Geneva, Switzerland. Electronic address:

Experiencing stressful or traumatic events can result in disabling clinical symptoms of maladaptive emotional memory retrieval, which are only partly addressed by the currently proposed treatments. Cortisol modulation has been shown to affect emotional memory retrieval and potentially reconsolidation, offering an opportunity for developing more efficient treatments for disorders with an emotional memory component. Here, we investigated if cortisol suppression after reactivation of emotional memories weakens later memory thereof. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03064530183123
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http://dx.doi.org/10.1016/j.psyneuen.2019.03.035DOI Listing
April 2019
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Motor cortex metabolite alterations in Amyotrophic Lateral Sclerosis assessed in vivo using edited and non-edited magnetic resonance spectroscopy.

Brain Res 2019 Apr 16. Epub 2019 Apr 16.

Biomedical MRI unit/ MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium. Electronic address:

Previous MRI and proton spectroscopy (H-MRS) studies have revealed impaired neuronal integrity and altered neurometabolite concentrations in the motor cortex of patients with amyotrophic lateral sclerosis (ALS). Here, we aim to use MRI with conventional and novel MRS sequences to further investigate neurometabolic changes in the motor cortex of ALS patients and their relation to clinical parameters. We utilized the novel HERMES (Hadamard Encoding and Reconstruction of MEGA-Edited Spectroscopy) MRS sequence to simultaneously quantify the inhibitory neurotransmitter GABA and antioxidant glutathione in ALS patients (n=7) and healthy controls (n=7). Read More

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http://dx.doi.org/10.1016/j.brainres.2019.04.018DOI Listing

Chronic cough and gastroesophageal reflux in children - CHEST Guideline and Expert Panel Report.

Chest 2019 Apr 16. Epub 2019 Apr 16.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, UMass Memorial Medical Center, Worcester, MA, USA.

Background: Whether gastroesophageal reflux (GER) or GER disease (GERD) causes chronic cough in children is controversial. Using the PICO format, we undertook 4 systematic reviews. For children with chronic cough (>4-weeks duration) and without underlying lung disease: (1) who do not have gastrointestinal GER symptoms, should empirical treatment for GERD be used? (2) with gastrointestinal GER symptoms, does treatment for GERD resolve the cough? (3) with or without gastrointestinal GER symptoms, what GER-based therapies should be used and for how long? (4) if GERD is suspected as the cause, what investigations and diagnostic criteria best determine GERD as the cause of the cough?

Methods: We used the CHEST Expert Cough Panel's protocol and American College of Chest Physicians (CHEST) methodological guidelines and GRADE framework. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00123692193083
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http://dx.doi.org/10.1016/j.chest.2019.03.035DOI Listing
April 2019
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Abortion Providers' experiences and views on self-managed medication abortion, an exploratory study.

Contraception 2019 Apr 16. Epub 2019 Apr 16.

University of Iowa Hospitals and Clinics, Department of Obstetrics and Gynecology, 200 Hawkins Drive, Iowa City, IA, 52242.

Objective: Data on the practice of self-managed medication abortion are limited, in part because this practice takes place purposefully outside of established healthcare systems. Given this, we aimed to ascertain abortion providers' familiarity with self-managed medication abortion and associated complications, compare regional differences, and evaluate provider attitudes.

Study Design: We distributed an online survey to members of Society for Family Planning, Association of Reproductive Health Providers, and the Abortion Care Network between July and September 2017 querying experiences with and opinions about self-managed abortion. Read More

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http://dx.doi.org/10.1016/j.contraception.2019.04.006DOI Listing
April 2019
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Productivity growth of skilled nursing facilities in the treatment of post-acute-care-intensive conditions.

PLoS One 2019 19;14(4):e0215876. Epub 2019 Apr 19.

School of Pharmacy, University of Southern California, Los Angeles, California, United States of America.

Background: Health care is believed to be suffered from a "cost disease," in which a heavy reliance on labor limits opportunities for efficiencies stemming from technological improvement. Although recent evidence shows that U.S. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215876PLOS

Negative affectivity and social inhibition are associated with increased cardiac readmission in patients with heart failure: A preliminary observation study.

PLoS One 2019 19;14(4):e0215726. Epub 2019 Apr 19.

Graduate Institute of Long-term Care, Tzu Chi University of Science and Technology, Hualien City, Hualien, Taiwan.

Background: Type D personality was hypothesized to influence clinical and patient-centered outcomes patients with heart failure. The aim of this study was to investigate the association between negative affectivity and social inhibition components of Type D personality and cardiac readmission in patients with heart failure.

Methods: A prospective observational study design was used. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215726PLOS

C1q nephropathy in adults is a form of focal segmental glomerulosclerosis in terms of clinical characteristics.

PLoS One 2019 19;14(4):e0215217. Epub 2019 Apr 19.

Korean GlomeuloNephritis Study Group, Korean Society of Nephrology, Seoul, Republic of Korea.

Although C1q nephropathy (C1qN) was introduced three decades ago, the clinical significance and renal outcomes of C1qN remain unclear. This study aimed to evaluate the clinical characteristics of C1qN, including renal outcomes, by performing a matched comparison within a multicenter cohort. We enrolled 6,413 adult patients who underwent kidney biopsy between January 2000 and January 2018 at three tertiary hospitals in Korea. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215217PLOS

Forward thinking with reverse mentoring.

Authors:
Sam Foster

Br J Nurs 2019 Apr;28(8):539

Chief Nurse, Oxford University Hospitals.

, Chief Nurse, Oxford University Hospitals, has been reading about reverse mentoring and considers its usefulness within the NHS. Read More

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http://dx.doi.org/10.12968/bjon.2019.28.8.539DOI Listing

The myth of the stable pulmonary arterial hypertension patient.

Am J Manag Care 2019 Mar;25(3 Suppl):S47-S52

Kaiser Foundation Health Plan and Hospitals, Downey, CA. Email:

Pulmonary arterial hypertension (PAH) is a rare, progressive disease that often leads to right heart failure and premature death. Despite increased awareness and an expanding treatment landscape in recent decades, long-term prognosis is poor for patients with PAH. Recently, emphasis has evolved from goal-oriented therapy to risk-assessment and achieving low-risk status. Read More

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March 2019
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Closed-loop insulin delivery in end-of-life care: a case report.

Diabet Med 2019 Apr 19. Epub 2019 Apr 19.

Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge, UK.

Background: Glucose management for people with diabetes approaching the end of life can be very challenging. The aim is to balance a minimally invasive approach with avoidance of symptomatic hypo- and hyperglycaemia.

Case Report: We present a case of a hospitalized individual whose glucose was managed with closed-loop insulin delivery within a randomized controlled trial setting during a period of terminal illness. Read More

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http://dx.doi.org/10.1111/dme.13974DOI Listing

A multicenter validation study for the EU-TIRADS using histological diagnosis as a gold standard.

Clin Endocrinol (Oxf) 2019 Apr 19. Epub 2019 Apr 19.

Thyroid Imaging and Cytopathology Centre, Paris, France.

Objective: Many systems for risk stratification of thyroid nodule with ultrasound (US) have been proposed and the EU-TIRADS issued by the ETA in 2017 was the last to have been published. The present study was undertaken to evaluate if the malignancy risk of each category corresponded to the given range of the guidelines and assess the diagnostic value of EU-TIRADS in a multi-institutional trial with histology as gold standard.

Design: Three institutions in Switzerland, France, and United Kingdom shared this retrospective study. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cen.13997
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http://dx.doi.org/10.1111/cen.13997DOI Listing
April 2019
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Factors associated with antibiotic prescribing for adults with acute conditions: an umbrella review across primary care and a systematic review focusing on primary dental care.

J Antimicrob Chemother 2019 Apr 19. Epub 2019 Apr 19.

University of Leeds/Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Introduction: One way to slow the spread of resistant bacteria is by improved stewardship of antibiotics: using them more carefully and reducing the number of prescriptions. With an estimated 7%-10% of antibiotic prescriptions globally originating from dental practices and up to 80% prescribed unnecessarily, dentistry has an important role to play. To support the design of new stewardship interventions through knowledge transfer between contexts, this study aimed to identify factors associated with the decision to prescribe antibiotics to adults presenting with acute conditions across primary care (including dentistry). Read More

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http://dx.doi.org/10.1093/jac/dkz152DOI Listing

US Emergency Department Visits and Hospital Discharges Among Uninsured Patients Before and After Implementation of the Affordable Care Act.

JAMA Netw Open 2019 Apr 5;2(4):e192662. Epub 2019 Apr 5.

US Acute Care Solutions, Canton, Ohio.

Importance: The US Patient Protection and Affordable Care Act of 2010 (ACA) was enacted in 2010 with several provisions that targeted reducing numbers of uninsured Americans.

Objective: To assess the numbers and proportion of emergency department (ED) visits (2006-2016) and hospital discharges (2006-2016) by uninsured patients, focusing on the 2014 ACA insurance reforms (Medicaid expansion, individual mandate, and private insurance exchanges).

Design, Setting, And Participants: Cross-sectional study of visitors to US EDs and patients discharged from US hospitals using National Hospital Ambulatory Care Survey data and Healthcare Cost and Utilization Project data, respectively, from 2006 to 2016. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.2662DOI Listing

Association of Peritumoral Radiomics With Tumor Biology and Pathologic Response to Preoperative Targeted Therapy for HER2 (ERBB2)-Positive Breast Cancer.

JAMA Netw Open 2019 Apr 5;2(4):e192561. Epub 2019 Apr 5.

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio.

Importance: There has been significant recent interest in understanding the utility of quantitative imaging to delineate breast cancer intrinsic biological factors and therapeutic response. No clinically accepted biomarkers are as yet available for estimation of response to human epidermal growth factor receptor 2 (currently known as ERBB2, but referred to as HER2 in this study)-targeted therapy in breast cancer.

Objective: To determine whether imaging signatures on clinical breast magnetic resonance imaging (MRI) could noninvasively characterize HER2-positive tumor biological factors and estimate response to HER2-targeted neoadjuvant therapy. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.2561DOI Listing

Association of Occupational Pesticide Exposure With Immunochemotherapy Response and Survival Among Patients With Diffuse Large B-Cell Lymphoma.

JAMA Netw Open 2019 Apr 5;2(4):e192093. Epub 2019 Apr 5.

Department of Biostatistics, Clinical Epidemiology, Public Health, and Innovation in Methodology, Nîmes University Hospital, University of Montpellier, Montpellier, France.

Importance: Professional use of pesticides is a risk factor for non-Hodgkin lymphoma. The main biological mechanisms of pesticides and chemotherapy are genotoxicity and reactive oxygen species generation. Cellular adaptation among patients exposed to low doses of genotoxic and oxidative compounds might hinder chemotherapy efficiency in patients with lymphoma. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.2093DOI Listing

Comparison of a Potential Hospital Quality Metric With Existing Metrics for Surgical Quality-Associated Readmission.

JAMA Netw Open 2019 Apr 5;2(4):e191313. Epub 2019 Apr 5.

Veterans Affairs, Palo Alto, Veterans Affairs Medical Center, Palo Alto, California.

Importance: The existing readmission quality metric does not meaningfully distinguish readmissions associated with surgical quality from those that are not associated with surgical quality and thus may not reflect the quality of surgical care.

Objective: To compare a quality metric that classifies readmissions associated with surgical quality with the existing metric of any unplanned readmission in a surgical population.

Design, Setting, And Participants: Cohort study using US nationwide administrative data collected on 4 high-volume surgical procedures performed at 103 Veterans Affairs hospitals from October 1, 2007, through September 30, 2014. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.1313DOI Listing

Bedside Rationing Under Resource Constraints-A National Survey of Ethiopian Physicians' Use of Criteria for Priority Setting.

AJOB Empir Bioeth 2019 Apr 19:1-11. Epub 2019 Apr 19.

a Research Group in Global Health Priorities, Department of Global Public Health and Primary Care , University of Bergen , Norway.

In low-income settings resource constraints force clinicians to make harsh choices. We examine the criteria Ethiopian physicians use in their bedside rationing decisions through a national survey at 49 public hospitals in Ethiopia. Substantial variation in weight given to different criteria were reported by the 587 participating physicians (response rate 91. Read More

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http://dx.doi.org/10.1080/23294515.2019.1583691DOI Listing

Idiopathic anaphylaxis.

Clin Exp Allergy 2019 Apr 19. Epub 2019 Apr 19.

Department of Allergy and Immunology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Idiopathic anaphylaxis (IA) or spontaneous anaphylaxis is a diagnosis of exclusion when no cause can be identified. The exact incidence and prevalence of IA is not known. The clinical manifestations of IA are similar to other known causes of anaphylaxis. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cea.13402
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http://dx.doi.org/10.1111/cea.13402DOI Listing
April 2019
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Feasibility of pulmonary valve imaging using transesophageal echocardiography upper esophageal view.

Echocardiography 2019 Apr 19. Epub 2019 Apr 19.

Division of Cardiology, University of Colorado School of Medicine, Aurora, Colorado.

Background: The present study designed to evaluate feasibility of transesophageal echocardiographic (TEE) imaging of the pulmonary valve (PV) at the transaortic upper esophageal (TAUE) window. We hypothesized that patients with larger aorta would be more likely to have visualization of the PV from this TAUE window.

Methods: 2D TEE images of the PV were prospectively acquired by one operator at the TAUE window looking through the aortic arch. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/echo.14332
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http://dx.doi.org/10.1111/echo.14332DOI Listing
April 2019
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Risks of substance uses, alcohol flush response, Helicobacter pylori infection and upper digestive tract diseases-An endoscopy cross-sectional study.

Kaohsiung J Med Sci 2019 Apr 18. Epub 2019 Apr 18.

Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

This study examines the effects of environmental hazards, including tobacco, alcohol/alcohol flush response, areca nut, and Helicobacter pylori (H pylori) infection on upper digestive diseases. This is a multi-hospital-based endoscopy-survey cross-sectional study. Subjects were received upper endoscopies in outpatient clinics at four hospitals in Taiwan between 2008 and 2013. Read More

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http://dx.doi.org/10.1002/kjm2.12071DOI Listing

Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women.

Cancer Med 2019 Apr 18. Epub 2019 Apr 18.

Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia.

An association between genetic variants in the vitamin D receptor (VDR) gene and epithelial ovarian cancer (EOC) was previously reported in women of African ancestry (AA). We sought to examine associations between genetic variants in VDR and additional genes from vitamin D biosynthesis and pathway targets (EGFR, UGT1A, UGT2A1/2, UGT2B, CYP3A4/5, CYP2R1, CYP27B1, CYP24A1, CYP11A1, and GC). Genotyping was performed using the custom-designed 533,631 SNP Illumina OncoArray with imputation to the 1,000 Genomes Phase 3 v5 reference set in 755 EOC cases, including 537 high-grade serous (HGSOC), and 1,235 controls. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.1996
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http://dx.doi.org/10.1002/cam4.1996DOI Listing
April 2019
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Factors associated with spontaneous stone passage in a contemporary cohort of patients presenting with acute ureteric colic. Results from the MIMIC Study (A Multi-centre cohort study evaluating the role of Inflammatory Markers In patients presenting with acute ureteric Colic).

BJU Int 2019 Apr 18. Epub 2019 Apr 18.

British Urology Researchers in Surgical Training (BURST), London, United Kingdom.

Objectives: There is conflicting data on the role of white blood cell count (WBC) and other inflammatory markers in spontaneous stone passage in patients with acute ureteric colic. The aim of the study was to assess the relationship of WBC and other routinely collected inflammatory and clinical markers including stone size, stone position and Medically Expulsive Therapy use (MET) with spontaneous stone passage (SSP) in a large contemporary cohort of patients with acute ureteric colic.

Subjects And Methods: Multi-centre retrospective cohort study coordinated by the British Urology Researchers in Surgical Training (BURST) Research Collaborative at 71 secondary care hospitals across 4 countries (United Kingdom, Republic of Ireland, Australia and New Zealand). Read More

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http://dx.doi.org/10.1111/bju.14777DOI Listing

Diagnostic accuracy of non-specialist versus specialist health workers in diagnosing hearing loss and ear disease in Malawi.

Trop Med Int Health 2019 Apr 18. Epub 2019 Apr 18.

International Centre for Evidence in Disability, London School of Hygiene& Tropical Medicine, UK.

Objective: To determine whether a non-specialist health worker can accurately undertake audiometry and otoscopy, the essential clinical examinations in a survey of hearing loss, instead of a highly skilled specialist (i.e. ENT or audiologist). Read More

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http://dx.doi.org/10.1111/tmi.13238DOI Listing

The clinical presentation caused by truncating CHD8 variants.

Clin Genet 2019 Apr 18. Epub 2019 Apr 18.

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre, United Kingdom.

Variants in the chromodomain helicase DNA-binding protein 8 (CHD8) have been associated with intellectual disability (ID), autism spectrum disorders (ASD) and overgrowth and CHD8 is one of the causative genes for OGID (overgrowth and ID). We investigated 25 individuals with CHD8 protein truncating variants (PTVs), including 10 previously unreported patients and found a male to female ratio of 2.7:1 (19:7) and a pattern of common features: macrocephaly (62. Read More

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http://doi.wiley.com/10.1111/cge.13554
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http://dx.doi.org/10.1111/cge.13554DOI Listing
April 2019
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Shock index thresholds to predict adverse outcomes in maternal hemorrhage and sepsis: a prospective cohort study.

Acta Obstet Gynecol Scand 2019 Apr 18. Epub 2019 Apr 18.

Department of Women and Children's Health, King's College London, London, UK.

Introduction: Shock Index (SI) is a predictor of hemodynamic compromise in obstetric patients. The Shock Index threshold for action is not well understood. We aimed to evaluate Shock Index thresholds as predictors of outcomes in obstetric patients. Read More

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http://dx.doi.org/10.1111/aogs.13626DOI Listing

Identifying the contribution to hospital performance among Chinese regions by an aggregate directional distance function.

Health Care Manag Sci 2019 Apr 19. Epub 2019 Apr 19.

Western Michigan University, Grand Rapids, MI, 49503, USA.

In this paper, we examine efficiency and total factor productivity for hospitals operating in China between the years of 2009-2016. Given reforms in China focusing on the hospital sector, it has been demonstrated that efficiency and productivity are important in meeting the overall objective of meeting more accessibility to hospital care for the population. Measuring an aggregate directional distance function is in itself a non-parametric approach, we report on the decomposition of hospital performance and found that between 2009 and 2010, technical inefficiency (using resources inefficiently) dominated overall inefficiency but beyond 2011-2016, mix inefficiency (misallocation of resources) was higher. Read More

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http://dx.doi.org/10.1007/s10729-019-09482-4DOI Listing

Improving follow up after predictive testing in Huntington's disease: evaluating a genetic counselling narrative group session.

J Community Genet 2019 Apr 18. Epub 2019 Apr 18.

Division of Evolution and Genomic Sciences, School of Biological Science, University of Manchester, Manchester, UK.

Recently updated Huntington's disease (HD) predictive testing guidelines emphasise clinicians' responsibility to facilitate emotional support following testing, regardless of the result. Yet models of post-test counselling support are poorly defined. Moreover, it is unclear how these might be best delivered. Read More

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http://dx.doi.org/10.1007/s12687-019-00416-9DOI Listing

Minimally invasive anterior cervical discectomy and fusion: a valid alternative to open techniques.

Authors:
Marcel Ivanov

Acta Neurochir (Wien) 2019 Apr 18. Epub 2019 Apr 18.

Department of Neurosurgery, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Glossop Rd, Sheffield, South Yorkshire, S10 2JF, UK.

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http://dx.doi.org/10.1007/s00701-019-03905-5DOI Listing

Variables of interest to predict glomerular filtration rate in preterm newborns in the first days of life.

Pediatr Nephrol 2019 Apr 18. Epub 2019 Apr 18.

Pediatric Nephrology Unit, Children and Adolescent Department, Children's Hospital, Geneva University Hospitals, 6 rue Willy Donzé CH-1211, Geneva 14, Switzerland.

Background: Measurement of neonatal renal function is challenging, and accurate, easy-to-use markers to estimate glomerular filtration rate (eGFR) are lacking. This study aimed to evaluate principal determinants of GFR in neonates and develop a predictive equation.

Methods: GFR was measured, using single injection inulin clearance, at median day 3 of life in 48 newborns. Read More

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http://dx.doi.org/10.1007/s00467-019-04257-zDOI Listing

Erratum zu: A case of Hughes-Stovin syndrome (incomplete Behçet’s disease) with extensive arterial involvement.

Z Rheumatol 2019 Apr 18. Epub 2019 Apr 18.

Faculty of Behavioral, Management and Social Sciences, Department Psychology, Health and Technology, University of Twente, Enschede, Niederlande.

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http://dx.doi.org/10.1007/s00393-019-0640-9DOI Listing

Juvenile Papillomatosis: A Case Report.

Eur J Breast Health 2019 Apr 15;15(2):130-134. Epub 2019 Feb 15.

Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium.

Juvenile papillomatosis of the breast, also known as Swiss cheese disease, is a rare and benign proliferative disorder affecting young women. These patients tend to have a strong family history of cancer. The lesion typically presents as a localized mass without sharp borders. Read More

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http://dx.doi.org/10.5152/ejbh.2019.4362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456279PMC

Evaluation of Illness Perception of Women with Breast Cancer in Turkey.

Eur J Breast Health 2019 Apr 1;15(2):98-104. Epub 2019 Apr 1.

Atatürk University School of Nursing, Erzurum, Turkey.

Objective: The aim of this study is to examine the illness perceptions of women with breast cancer and possible relationships between these perceptions and descriptive characteristics such as sociodemographic and clinical characteristics in Turkey.

Materials And Methods: The study was conducted in compliance with correlational, descriptive research principles. Three hundred eighty women with breast cancer who were treated in various hospitals in seven regions of the country were included in the study. Read More

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http://www.eurjbreasthealth.com/eng/makale/684/59/Full-Text
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http://dx.doi.org/10.5152/ejbh.2019.4317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456280PMC
April 2019
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A Systematic Review of Right Ventricular Diastolic Assessment by 4D Flow CMR.

Biomed Res Int 2019 14;2019:6074984. Epub 2019 Mar 14.

Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, UK.

Background: Four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) is a noninvasive novel imaging technology that can be used to visualise and assess right ventricular function. The aim of this systematic review is to summarise the literature available on 4D flow CMR methods used to determine right ventricular diastolic function.

Methods: A systematic review of current literature was carried out to ascertain what is known about right ventricular assessment by quantification of 4D flow CMR. Read More

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http://dx.doi.org/10.1155/2019/6074984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437735PMC

Sleep disturbances in HIV-infected patients associated with depression and high risk of obstructive sleep apnea.

SAGE Open Med 2019 8;7:2050312119842268. Epub 2019 Apr 8.

Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Objective: To evaluate sleep disturbances in a diverse, contemporary HIV-positive patient cohort and to identify demographic, clinical, and immune correlates.

Methods: A convenience sample of 176 patients from a racially and ethnically diverse HIV-positive patient cohort in an urban population. This was a cross-sectional, epidemiologic study. Read More

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http://dx.doi.org/10.1177/2050312119842268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454647PMC
April 2019
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Comparison of the Efficacy between Conventional Moxibustion and Smoke-Free Moxibustion on Knee Osteoarthritis: A Randomized Controlled Trial.

Evid Based Complement Alternat Med 2019 14;2019:1291947. Epub 2019 Mar 14.

School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Objective: The aim of this study was to investigate the difference of efficacy between conventional moxibustion (CM) and smoke-free moxibustion (SM) for patients with osteoarthritis of the knee (KOA).

Methods: This is a multicentre, randomized, single blinded, parallel-group clinical trial. Patients with KOA were randomly allocated to CM group (69) and SM group (69) in 7 hospitals of China. Read More

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http://dx.doi.org/10.1155/2019/1291947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437731PMC

Psychiatry Residents in China: Socio-Demographic Characteristics, Career Satisfaction, and Related Factors.

Front Psychiatry 2019 2;10:177. Epub 2019 Apr 2.

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States.

To study the socio-demographic characteristics, the working environment, and the level of career satisfaction among psychiatry residents in China. This was a part of a large-scale, nation-wide online survey of hospitals, healthcare professionals, and patients. Data, including socio-demographics, work hours, income, job satisfaction, and intention to quit were collected anonymously. Read More

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https://www.frontiersin.org/article/10.3389/fpsyt.2019.00177
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http://dx.doi.org/10.3389/fpsyt.2019.00177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454050PMC
April 2019
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mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR.

Front Cell Neurosci 2019 2;13:115. Epub 2019 Apr 2.

Shriners Hospitals Pediatric Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.

The mechanistic target of rapamycin (mTOR) Complex 1 (mTORC1) controls growth and proliferation of non-neuronal cells, while during neuronal development mTORC1 responds to glutamate and neurotrophins to promote neuronal migration and dendritic arborization. Recent studies reveal that mTORC1 signaling complexes are assembled on lysosomal membranes, but how mTORC1 membrane targeting is regulated is not fully clear. Our examination of palmitoyl-proteomic databases and additional bioinformatic analyses revealed that several mTORC1 proteins are predicted to undergo covalent modification with the lipid palmitate. Read More

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http://dx.doi.org/10.3389/fncel.2019.00115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454084PMC

Acceptability of Mental Health Facilities and De-addiction Centers in India.

J Exp Neurosci 2019 7;13:1179069519839990. Epub 2019 Apr 7.

Department of Pharmacology, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow, India.

Not much is known about disease prevalence, treatment outcomes, trained manpower, programs, and patients' awareness of diseases from South Asia, compared with the Western world. While other aspects are improving, the quantitative evaluation of awareness of diseases is lagging. Compared with other diseases, the situation for mental health disorders and addiction is worse. Read More

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http://dx.doi.org/10.1177/1179069519839990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454643PMC
April 2019
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Ventriculoperitoneal Shunt Disconnection, Shunt Migration, and Silent Bowel Perforation in a 10-Year-Old Boy.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):342-345

Department of Pediatric Surgery, Gandhi Medical College and Associated, Kamla Nehru and Hamidia Hospitals, Bhopal, Madhya Pradesh, India.

A 10-year-old boy was admitted with chest wall infection around the implanted ventriculoperitoneal shunt (VPS) catheter of 5 days. He had received a right-sided, medium pressure, whole-length VPS for hydrocephalus, following tubercular meningitis at the age of 3 years. Seven years, 9 months following VPS implantation, he was admitted with shunt tract infection at the chest area for 5 days. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_329_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454935PMC

Pattern of Emergent Head Computed Tomography Findings in a Tertiary Care Hospital during off Working Hours: Retrospective Analysis.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):207-211

Department of Radiodiagnosis, Indian Naval Hospital Ship Asvini, Mumbai, Maharashtra, India.

Introduction: Emergency head computed tomography (CT) is rising exponentially during off working hours due to evidence-based medicine, patient's expectation and desires, easy availability and apprehension of medico-legal cases, thereby raising health-care cost. There is huge gap in demand and supply of radiologist, especially during off working hours. There is need to know the pattern of emergency head findings. Read More

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http://www.ruralneuropractice.com/text.asp?2019/10/2/207/254
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http://dx.doi.org/10.4103/jnrp.jnrp_362_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454959PMC
April 2019
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Study of Ischemia Modified Albumin as a Biomarker in Acute Ischaemic Stroke.

Ann Neurosci 2018 Dec 28;25(4):187-190. Epub 2018 Jun 28.

Narayana Medical College and Hospitals, Nellore, India.

Background And Purpose: Stroke is one of the leading causes of mortality and long-term disability. Prompt diagnosis and treatment of stroke are crucial for a better outcome. A blood test, which serves as a biomarker in rural areas will help in immediately transferring patients to a hospital for thrombolytic therapy. Read More

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http://dx.doi.org/10.1159/000488188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470340PMC
December 2018

Prevalence, Demographic Profile, and Psychological Aspects of Epilepsy in North-Western India: A Community-Based Observational Study.

Ann Neurosci 2018 Dec 12;25(4):177-186. Epub 2018 Jun 12.

Professor Preventive and Social Medicine, SMS Medical College, Jaipur, India.

Aims: This study was undertaken to determine the prevalence of active epilepsy, assess the sociodemographic profile, and psychological aspects of epilepsy in the Jaipur district of Rajasthan, India.

Methods: We conducted a community-based, cross-sectional observational study covering both rural ( = 165,660) and urban ( = 179,142) populations of Jaipur district using a house-to-house survey. An adapted, pre-designed World Health Organization screening questionnaire was used to identify the cases. Read More

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https://www.karger.com/Article/FullText/487072
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http://dx.doi.org/10.1159/000487072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470329PMC
December 2018
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"Honeycomb" pattern of gallbladder wall thickening - A forward step in early diagnosis of "Severe Dengue Fever".

Indian J Radiol Imaging 2019 Jan-Mar;29(1):14-18

Department of Radiology, Apollo Hospitals International Limited, Gandhinagar, India.

Aims And Objectives: To study "Honeycomb" pattern of gallbladder wall thickening (GBWT) in dengue fever (DF) and to assess its clinical significance in early diagnosis of severe DF.

Materials And Methods: A total 244 patients of DF were studied, 84 patients were classified as severe DF, 61 patients as DF with warning signs, and 99 patients as DF without warning signs. Abdominal ultrasound was performed for assessment of GBWT patterns, hepatomegaly, splenomegaly, pancreatic enlargement, ascites, pleural effusion, and other additional findings were recorded in severe DF cases. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_363_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467033PMC

Turner-Warwick scrotal drop back procedure as a revision perineal urethrostomy.

Indian J Urol 2019 Apr-Jun;35(2):159-160

Department of Urology, KIMS, Amalapuram, Andhra Pradesh, India.

Stomal stenosis post perineal urethrostomy (PU) is a common problem. Management options for patients with PU stomal stenosis include dilatation, buccal mucosal augmentation of stoma, PU revision, and continent catheterizable stoma. In the present case, Turner-Warwick scrotal drop back procedure was performed as revision PU. Read More

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http://dx.doi.org/10.4103/iju.IJU_345_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458805PMC

Assessment of predisposing factors in myofascial pain syndrome and the analgesic effect of trigger point injections - A primary therapeutic interventional clinical trial.

Indian J Anaesth 2019 Apr;63(4):300-303

Department of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, India.

Background And Aims: Myofascial pain syndrome (MPS) is a common cause of chronic musculoskeletal pain, characterised by myofascial trigger points (TPs). TP injection is an established technique for management of MPS. In this study, we analysed the efficacy of myofascial TP injection of lignocaine and the influencing biomechanical factors on MPS. Read More

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http://dx.doi.org/10.4103/ija.IJA_6_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460974PMC

Adenocarcinoma of ileum: a case report.

J Pak Med Assoc 2019 Apr;69(4):580-583

Kulsumbai Valika Social Security S.I.T.E. Hospital, Karachi, Pakistan.

Small bowel cancers are a rare group of cancers of the gastrointestinal tract. Adenocarcinoma of ileum is an even rarer pathology to come across. We had a case of small bowel adenocarcinoma (SBA) who presented with recurrent abdominal pain and vomiting to different local hospitals. Read More

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April 2019
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Women's preferences and factors influencing their obstetric care service utilization in rural Sindh: A Cross sectional Study.

J Pak Med Assoc 2019 Apr;69(4):576-579

Health Services Academy Islamabad.

The objective of this study was to explore women's preferences and factors influencing the obstetric services in a rural setting of Sindh Province. This cross sectional study was conducted on 100 women who were interviewed by using a validated questionnaire. The women who had given birth during the year preceding the study were eligible for inclusion in the study. Read More

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